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Prostate Cancer

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February 2025
1. ZHANG C, Ding J, Lim KS, Zhou W, et al
   JMJD6 Rewires ATF4-Dependent Glutathione Metabolism to Confer Ferroptosis Resistance in SPOP-Mutated Prostate Cancer.
   Cancer Res. 2025 Feb 4. doi: 10.1158/0008-5472.CAN-23-2796.
   PubMed     Abstract available
   
   
   December 2024
2. SIPOLA J, Munzur AD, Kwan EM, Seo CCY, et al
   Plasma cell-free DNA chromatin immunoprecipitation profiling depicts phenotypic and clinical heterogeneity in advanced prostate cancer.
   Cancer Res. 2024 Dec 9. doi: 10.1158/0008-5472.CAN-24-2052.
   PubMed     Abstract available
   
   
   November 2024
3. BAE TH, Sung KW, Pham TM, Najy AJ, et al
   An Autophagy-Targeting Chimera Induces Degradation of Androgen Receptor Mutants and AR-v7 in Castration-Resistant Prostate Cancer.
   Cancer Res. 2024 Nov 12. doi: 10.1158/0008-5472.CAN-24-0591.
   PubMed     Abstract available
   
   
   
4. MCQUILLEN CN, Brady NJ
   ASCL1 Drives the Development of Neuroendocrine Prostate Cancer.
   Cancer Res. 2024;84:3499-3501.
   PubMed     Abstract available
   
   
   October 2024
5. ZHANG L, Troccoli CI, Mateo-Victoriano B, Misiara Lincheta L, et al
   Stimulating Soluble Guanylyl Cyclase with the Clinical Agonist Riociguat Restrains the Development and Progression of Castration-Resistant Prostate Cancer.
   Cancer Res. 2024 Oct 10. doi: 10.1158/0008-5472.CAN-24-0133.
   PubMed     Abstract available
   
   
   September 2024
6. RODARTE KE, Nir Heyman S, Guo L, Flores L, et al
   Neuroendocrine Differentiation in Prostate Cancer Requires ASCL1.
   Cancer Res. 2024 Sep 12. doi: 10.1158/0008-5472.CAN-24-1388.
   PubMed     Abstract available
   
   
   August 2024
7. SONG H, Lu T, Han D, Zhang J, et al
   YAP1 Inhibition Induces Phenotype Switching of Cancer-Associated Fibroblasts to Tumor Suppressive in Prostate Cancer.
   Cancer Res. 2024 Aug 13. doi: 10.1158/0008-5472.CAN-24-0932.
   PubMed     Abstract available
   
   
   
8. NING S, Armstrong CM, Xing E, Leslie AR, et al
   LX1 Targets Androgen Receptor Variants and AKR1C3 to overcome Therapy Resistance in Advanced Prostate Cancer.
   Cancer Res. 2024 Aug 1. doi: 10.1158/0008-5472.CAN-24-0440.
   PubMed     Abstract available
   
   
   July 2024
9. SHRESTHA R, Chesner LN, Zhang M, Zhou S, et al
   An Atlas of Accessible Chromatin in Advanced Prostate Cancer Reveals the Epigenetic Evolution during Tumor Progression.
   Cancer Res. 2024 Jul 11. doi: 10.1158/0008-5472.CAN-24-0890.
   PubMed     Abstract available
   
   
   
10. YOO YA, Quan S, Yang W, Guo Q, et al
    Asparagine Dependency is a Targetable Metabolic Vulnerability in TP53-Altered Castration-Resistant Prostate Cancer.
    Cancer Res. 2024 Jul 3. doi: 10.1158/0008-5472.CAN-23-2910.
    PubMed     Abstract available
    
    
    June 2024
11. ZHANG W, Maeser D, Lee A, Huang Y, et al
    Integration of Pan-Cancer Cell Line and Single-Cell Transcriptomic Profiles Enables Inference of Therapeutic Vulnerabilities in Heterogeneous Tumors.
    Cancer Res. 2024;84:2021-2033.
    PubMed     Abstract available
    
    
    
12. LI W, Guo F, Zeng R, Liang H, et al
    CDK4/6 Alters TBK1 Phosphorylation to Inhibit the STING Signaling Pathway in Prostate Cancer.
    Cancer Res. 2024 Jun 11. doi: 10.1158/0008-5472.CAN-23-3704.
    PubMed     Abstract available
    
    
    
13. BOUFAIED N, Chetta P, Hallal T, Cacciatore S, et al
    Obesogenic High-Fat Diet and MYC Cooperate to Promote Lactate Accumulation and Tumor Microenvironment Remodeling in Prostate Cancer.
    Cancer Res. 2024;84:1834-1855.
    PubMed     Abstract available
    
    
    
14. FRIGO DE
    Diet and Tumor Genetics Conspire to Promote Prostate Cancer Metabolism and Shape the Tumor Microenvironment.
    Cancer Res. 2024;84:1742-1744.
    PubMed     Abstract available
    
    
    
15. GALLAGHER K, Strobl MAR, Park DS, Spoendlin FC, et al
    Mathematical Model-Driven Deep Learning Enables Personalized Adaptive Therapy.
    Cancer Res. 2024;84:1929-1941.
    PubMed     Abstract available
    
    
    April 2024
16. SHRESTHA RK, Nassar ZD, Hanson AR, Iggo R, et al
    ACSM1 and ACSM3 regulate fatty acid metabolism to support prostate cancer growth and constrain ferroptosis.
    Cancer Res. 2024 Apr 24. doi: 10.1158/0008-5472.CAN-23-1489.
    PubMed     Abstract available
    
    
    
17. CUNNINGHAM M, Schiewer MJ
    PARP-ish: Gaps in Molecular Understanding and Clinical Trials Targeting PARP Exacerbate Racial Disparities in Prostate Cancer.
    Cancer Res. 2024 Apr 18. doi: 10.1158/0008-5472.CAN-23-3458.
    PubMed     Abstract available
    
    
    
18. MURPHY S, Rahmy S, Gan D, Liu G, et al
    Ketogenic diet alters the epigenetic and immune landscape of prostate cancer to overcome resistance to immune checkpoint blockade therapy.
    Cancer Res. 2024 Apr 8. doi: 10.1158/0008-5472.CAN-23-2742.
    PubMed     Abstract available
    
    
    March 2024
19. SHU F, Liu H, Chen X, Liu Y, et al
    m6A modification promotes EMT and metastasis of castration-resistant prostate cancer by upregulating NFIB.
    Cancer Res. 2024 Mar 27. doi: 10.1158/0008-5472.CAN-23-1954.
    PubMed     Abstract available
    
    
    January 2024
20. ZHAO J, Xu N, Zhu S, Nie L, et al
    Genomic and Evolutionary Characterization of Concurrent Intraductal Carcinoma and Adenocarcinoma of the Prostate.
    Cancer Res. 2024;84:154-167.
    PubMed     Abstract available
    
    
    December 2023
21. MISHRA R, Blinka S, Hsieh AC
    Citron Kinase Is a Druggable Target in Treatment-Resistant Prostate Cancer.
    Cancer Res. 2023;83:4008-4009.
    PubMed     Abstract available
    
    
    
22. AWAD D, Cao PHA, Pulliam TL, Spradlin M, et al
    Adipose triglyceride lipase is a therapeutic target in advanced prostate cancer that promotes metabolic plasticity.
    Cancer Res. 2023 Dec 1. doi: 10.1158/0008-5472.CAN-23-0555.
    PubMed     Abstract available
    
    
    October 2023
23. RAWAT C, Ben-Salem S, Singh N, Chauhan G, et al
    Prostate cancer progression relies on the mitotic kinase citron kinase.
    Cancer Res. 2023 Oct 6. doi: 10.1158/0008-5472.CAN-23-0883.
    PubMed     Abstract available
    
    
    September 2023
24. LI Z, Ning K, Zhao D, Zhou Z, et al
    Targeting the metabolic enzyme PGAM2 overcomes enzalutamide resistance in castration-resistant prostate cancer by inhibiting BCL2 signaling.
    Cancer Res. 2023 Sep 7. doi: 10.1158/0008-5472.CAN-23-0308.
    PubMed     Abstract available
    
    
    
25. BORDELEAU F
    Using Machine Learning to Predict TP53 Mutation Status and Aggressiveness of Prostate Cancer from Routine Histology Images.
    Cancer Res. 2023;83:2809-2810.
    PubMed     Abstract available
    
    
    
26. NYQUIST MD, Coleman IM, Lucas JM, Li D, et al
    Supraphysiological Androgens Promote the Tumor Suppressive Activity of the Androgen Receptor through cMYC Repression and Recruitment of the DREAM Complex.
    Cancer Res. 2023;83:2938-2951.
    PubMed     Abstract available
    
    
    August 2023
27. GALLAHER J, Strobl M, West J, Gatenby R, et al
    Intermetastatic and Intrametastatic Heterogeneity Shapes Adaptive Therapy Cycling Dynamics.
    Cancer Res. 2023;83:2775-2789.
    PubMed     Abstract available
    
    
    
28. SUN R, Yan B, Li H, Ding D, et al
    Androgen receptor variants confer castration resistance in prostate cancer by counteracting antiandrogen-induced ferroptosis.
    Cancer Res. 2023 Aug 1:CAN-23-0285. doi: 10.1158/0008-5472.CAN-23-0285.
    PubMed     Abstract available
    
    
    July 2023
29. LI X, Mu P
    The Critical Interplay of CAF Plasticity and Resistance in Prostate Cancer.
    Cancer Res. 2023 Jul 28:CAN-23-2260. doi: 10.1158/0008-5472.CAN-23-2260.
    PubMed     Abstract available
    
    
    June 2023
30. PIZURICA M, Larmuseau M, Van der Eecken K, de Schaetzen van Brienen L, et al
    Whole slide imaging-based prediction of TP53 mutations identifies an aggressive disease phenotype in prostate cancer.
    Cancer Res. 2023 Jun 23:CAN-22-3113. doi: 10.1158/0008-5472.CAN-22-3113.
    PubMed     Abstract available
    
    
    
31. LUNDBERG A, Zhang M, Aggarwal R, Li H, et al
    The genomic and epigenomic landscape of double-negative metastatic prostate cancer.
    Cancer Res. 2023 Jun 8:CAN-23-0593. doi: 10.1158/0008-5472.CAN-23-0593.
    PubMed     Abstract available
    
    
    April 2023
32. FLOC'H N, Kinkade CW, Kobayashi T, Aytes A, et al
    Editor's Note: Dual Targeting of the Akt/mTOR Signaling Pathway Inhibits Castration-Resistant Prostate Cancer in a Genetically Engineered Mouse Model.
    Cancer Res. 2023;83:1160.
    PubMed    
    
    
    
33. OUYANG X, Jessen WJ, Al-Ahmadie H, Serio AM, et al
    Editor's Note: Activator Protein-1 Transcription Factors Are Associated with Progression and Recurrence of Prostate Cancer.
    Cancer Res. 2023;83:1161.
    PubMed    
    
    
    
34. WANG K, Ma F, Arai S, Wang Y, et al
    WNT5a Signaling through ROR2 Activates the Hippo Pathway to Suppress YAP1 Activity and Tumor Growth.
    Cancer Res. 2023;83:1016-1030.
    PubMed     Abstract available
    
    
    March 2023
35. ZHANG X, Cheng L, Gao C, Chen J, et al
    Androgen Signaling Contributes to Sex Differences in Cancer by Inhibiting NF-kappaB Activation in T Cells and Suppressing Antitumor Immunity.
    Cancer Res. 2023;83:906-921.
    PubMed     Abstract available
    
    
    
36. LI M, Liu M, Han W, Wang Z, et al
    LSD1 inhibition disrupts super-enhancer driven oncogenic transcriptional programs in castration-resistant prostate cancer.
    Cancer Res. 2023 Mar 6:CAN-22-2433. doi: 10.1158/0008-5472.CAN-22-2433.
    PubMed     Abstract available
    
    
    February 2023
37. AO J, Shao X, Liu Z, Liu Q, et al
    Stimulated Raman Scattering Microscopy Enables Gleason Scoring of Prostate Core Needle Biopsy by a Convolutional Neural Network.
    Cancer Res. 2023;83:641-651.
    PubMed     Abstract available
    
    
    
38. ZHANG H, Jin X, Huang H
    Deregulation of SPOP in Cancer.
    Cancer Res. 2023;83:489-499.
    PubMed     Abstract available
    
    
    
39. BLATTI C, de la Fuente Cedeno J, Gao H, Marin-Goni I, et al
    Bayesian machine learning enables identification of transcriptional network disruptions associated with drug-resistant prostate cancer.
    Cancer Res. 2023 Feb 13:CAN-22-1910. doi: 10.1158/0008-5472.CAN-22-1910.
    PubMed     Abstract available
    
    
    
40. GALLON J, Rodriguez-Calero A, Benjak A, Akhoundova D, et al
    DNA methylation landscapes of prostate cancer brain metastasis are shaped by early driver genetic alterations.
    Cancer Res. 2023 Feb 7:CAN-22-2236. doi: 10.1158/0008-5472.CAN-22-2236.
    PubMed     Abstract available
    
    
    January 2023
41. PATTERSON JC, Varkaris A, Croucher PJP, Ridinger M, et al
    Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling.
    Cancer Res. 2023;83:219-238.
    PubMed     Abstract available
    
    
    November 2022
42. CHOU J, Egusa EA, Wang S, Badura ML, et al
    Immunotherapeutic targeting and PET imaging of DLL3 in small cell neuroendocrine prostate cancer.
    Cancer Res. 2022 Nov 9. pii: 710533. doi: 10.1158/0008-5472.CAN-22-1433.
    PubMed     Abstract available
    
    
    
43. WU A, Attard G
    Accidentals of the DNA Symphony.
    Cancer Res. 2022;82:3880-3881.
    PubMed     Abstract available
    
    
    October 2022
44. SJOSTROM M, Zhao SG, Levy S, Zhang M, et al
    The 5-Hydroxymethylcytosine Landscape of Prostate Cancer.
    Cancer Res. 2022 Oct 17:OF1-OF15. doi: 10.1158/0008-5472.CAN-22-1123.
    PubMed     Abstract available
    
    
    September 2022
45. WANG J, Ying G, Wang J, Jung Y, et al
    Retraction: Characterization of Phosphoglycerate Kinase-1 Expression of Stromal Cells Derived from Tumor Microenvironment in Prostate Cancer Progression.
    Cancer Res. 2022;82:3405.
    PubMed    
    
    
    
46. WANG J, Lu Y, Wang J, Koch AE, et al
    Retraction: CXCR6 Induces Prostate Cancer Progression by the AKT/Mammalian Target of Rapamycin Signaling Pathway.
    Cancer Res. 2022;82:3406.
    PubMed    
    
    
    
47. BHOWMICK S, Bhowmick NA
    RARgamma: The Bone of Contention for Endothelial Cells in Prostate Cancer Metastasis.
    Cancer Res. 2022;82:2975-2976.
    PubMed     Abstract available
    
    
    
48. LI H, Wang Y, Lin K, Venkadakrishnan VB, et al
    CHD1 Promotes Sensitivity to Aurora Kinase Inhibitors by Suppressing Interaction of AURKA with Its Coactivator TPX2.
    Cancer Res. 2022;82:3088-3101.
    PubMed     Abstract available
    
    
    July 2022
49. YU G, Corn PG, Shen PF, Song JH, et al
    Retinoic acid receptor activation reduces metastatic prostate cancer bone lesions by blocking the endothelial-to-osteoblast transition.
    Cancer Res. 2022 Jul 8. pii: 706930. doi: 10.1158/0008-5472.CAN-22-0170.
    PubMed     Abstract available
    
    
    
50. DAVIDSON SM, Schmidt DR, Heyman JE, O'Brien JP, et al
    Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma.
    Cancer Res. 2022;82:2403-2416.
    PubMed     Abstract available
    
    
    June 2022
51. SHANGGUAN X, Ma Z, Yu M, Ding J, et al
    Squalene epoxidase metabolic dependency is a targetable vulnerability in castration-resistant prostate cancer.
    Cancer Res. 2022 Jun 29. pii: 705311. doi: 10.1158/0008-5472.CAN-21-3822.
    PubMed     Abstract available
    
    
    
52. BERCHUCK JE, Adib E, Abou Alaiwi S, Dash AK, et al
    The prostate cancer androgen receptor cistrome in African American men associates with upregulation of lipid metabolism and immune response.
    Cancer Res. 2022 Jun 22. pii: 705059. doi: 10.1158/0008-5472.CAN-21-3552.
    PubMed     Abstract available
    
    
    
53. PATEL R, Ford CA, Rodgers L, Rushworth LK, et al
    Cyclocreatine suppresses creatine metabolism and impairs prostate cancer progression.
    Cancer Res. 2022 Jun 8. pii: 704813. doi: 10.1158/0008-5472.CAN-21-1301.
    PubMed     Abstract available
    
    
    May 2022
54. QIN L, Chung YM, Berk M, Naelitz B, et al
    Hypoxia-reoxygenation couples 3betaHSD1 enzyme and cofactor upregulation to facilitate androgen biosynthesis and hormone therapy resistance in prostate cancer.
    Cancer Res. 2022 May 10. pii: 696493. doi: 10.1158/0008-5472.CAN-21-4256.
    PubMed     Abstract available
    
    
    
55. ABATE-SHEN C, Nunes de Almeida F
    Establishment of the LNCaP Cell Line - The Dawn of an Era for Prostate Cancer Research.
    Cancer Res. 2022;82:1689-1691.
    PubMed     Abstract available
    
    
    April 2022
56. RODRIGUEZ Y, Unno K, Truica MI, Chalmers ZR, et al
    A genome-wide CRISPR activation screen identifies PRRX2 as a regulator of enzalutamide resistance in prostate cancer.
    Cancer Res. 2022 Apr 11. pii: 694256. doi: 10.1158/0008-5472.CAN-21-3565.
    PubMed     Abstract available
    
    
    March 2022
57. LI R, Zhu J, Zhong W, Jia Z, et al
    Comprehensive evaluation of machine learning models and gene expression signatures for prostate cancer prognosis using large population cohorts.
    Cancer Res. 2022 Mar 31. pii: 682141. doi: 10.1158/0008-5472.CAN-21-3074.
    PubMed     Abstract available
    
    
    
58. KARABACAK NM, Zheng Y, Dubash TD, Burr R, et al
    Differential Kinase Activity Across Prostate Tumor Compartments Defines Sensitivity to Target Inhibition.
    Cancer Res. 2022;82:1084-1097.
    PubMed     Abstract available
    
    
    February 2022
59. BOONEN RACM, Wiegant WW, Celosse N, Vroling B, et al
    Functional Analysis Identifies Damaging CHEK2 Missense Variants Associated with Increased Cancer Risk.
    Cancer Res. 2022;82:615-631.
    PubMed     Abstract available
    
    
    
60. IPPOLITO L, Comito G, Parri M, Iozzo M, et al
    Lactate rewires lipid metabolism and sustains a metabolic-epigenetic axis in prostate cancer.
    Cancer Res. 2022 Feb 8. pii: 0008-5472.CAN-21-0914.
    PubMed     Abstract available
    
    
    
61. MA F, Arai S, Wang K, Calagua C, et al
    Autocrine canonical Wnt signaling primes noncanonical signaling through ROR1 in metastatic castration-resistant prostate cancer.
    Cancer Res. 2022 Feb 7. pii: 0008-5472.CAN-21-1807.
    PubMed     Abstract available
    
    
    January 2022
62. MANDIGO AC, Shafi AA, McCann JJ, Yuan W, et al
    Novel Oncogenic Transcription Factor Cooperation in RB-Deficient Cancer.
    Cancer Res. 2022;82:221-234.
    PubMed     Abstract available
    
    
    December 2021
63. JIANG X, Guo S, Wang S, Zhang Y, et al
    EIF4A3-induced circARHGAP29 promotes aerobic glycolysis in docetaxel-resistant prostate cancer through IGF2BP2/c-Myc/LDHA signaling.
    Cancer Res. 2021 Dec 28. pii: 0008-5472.CAN-21-2988.
    PubMed     Abstract available
    
    
    
64. XIE W, Reder NP, Koyuncu CF, Leo P, et al
    Prostate cancer risk stratification via non-destructive 3D pathology with deep learning-assisted gland analysis.
    Cancer Res. 2021 Dec 1. pii: 0008-5472.CAN-21-2843.
    PubMed     Abstract available
    
    
    
65. HAWLEY JR, Zhou S, Arlidge C, Grillo G, et al
    Reorganization of the 3D Genome Pinpoints Noncoding Drivers of Primary Prostate Tumors.
    Cancer Res. 2021;81:5833-5848.
    PubMed     Abstract available
    
    
    November 2021
66. JUNG Y, Cackowski FC, Yumoto K, Decker AM, et al
    Correction: CXCL12gamma Promotes Metastatic Castration-Resistant Prostate Cancer by Inducing Cancer Stem Cell and Neuroendocrine Phenotypes.
    Cancer Res. 2021;81:5777.
    PubMed    
    
    
    
67. GIL V, Miranda S, Riisnaes R, Gurel B, et al
    HER3 is an Actionable Target in Advanced Prostate Cancer.
    Cancer Res. 2021 Nov 9. pii: 0008-5472.CAN-21-3360.
    PubMed     Abstract available
    
    
    
68. GHILDIYAL R, Sawant M, Renganathan A, Mahajan K, et al
    Loss of long non-coding RNA NXTAR in prostate cancer augments androgen receptor expression and enzalutamide resistance.
    Cancer Res. 2021 Nov 5. pii: 0008-5472.CAN-20-3845.
    PubMed     Abstract available
    
    
    
69. AL-JANABI H, Lewis CE
    Macrophage Regulation of the Development of Castration-Resistant Prostate Cancer.
    Cancer Res. 2021;81:5399-5400.
    PubMed     Abstract available
    
    
    October 2021
70. KUMAR R, Mendonca J, Owoyemi O, Boyapati K, et al
    Supraphysiological testosterone induces ferroptosis and activates immune pathways through nucleophagy in prostate cancer.
    Cancer Res. 2021 Oct 13. pii: 0008-5472.CAN-20-3607.
    PubMed     Abstract available
    
    
    August 2021
71. BUTLER LM, Mah CY, Machiels J, Vincent AD, et al
    Lipidomic profiling of clinical prostate cancer reveals targetable alterations in membrane lipid composition.
    Cancer Res. 2021 Aug 6. pii: 0008-5472.CAN-20-3863.
    PubMed     Abstract available
    
    
    July 2021
72. LABRECQUE MP, Brown LG, Coleman IM, Lakely B, et al
    RNA splicing factors SRRM3 and SRRM4 distinguish molecular phenotypes of castration-resistant neuroendocrine prostate cancer.
    Cancer Res. 2021 Jul 26. pii: 0008-5472.CAN-21-0307.
    PubMed     Abstract available
    
    
    
73. EL-KENAWI A, Dominguez-Viqueira W, Liu M, Awasthi S, et al
    Macrophage-derived cholesterol contributes to therapeutic resistance in prostate cancer.
    Cancer Res. 2021 Jul 23. pii: 0008-5472.CAN-20-4028.
    PubMed     Abstract available
    
    
    
74. MAVURA MY, Huang FW
    How Cancer Risk SNPs May Contribute to Prostate Cancer Disparities.
    Cancer Res. 2021;81:3764-3765.
    PubMed     Abstract available
    
    
    
75. TAKAYAMA KI, Honma T, Suzuki T, Kondoh Y, et al
    Targeting Epigenetic and Posttranscriptional Gene Regulation by PSF Impairs Hormone Therapy-Refractory Cancer Growth.
    Cancer Res. 2021;81:3495-3508.
    PubMed     Abstract available
    
    
    
76. STEINER MC, Marston JL, Iniguez LP, Bendall ML, et al
    Locus-Specific Characterization of Human Endogenous Retrovirus Expression in Prostate, Breast, and Colon Cancers.
    Cancer Res. 2021;81:3449-3460.
    PubMed     Abstract available
    
    
    June 2021
77. PALLMANN N, Deng K, Livgard M, Tesikova M, et al
    Stress mediated reprogramming of prostate cancer one-carbon cycle drives disease progression.
    Cancer Res. 2021 Jun 28. pii: 0008-5472.CAN-20-3956.
    PubMed     Abstract available
    
    
    
78. WEI J, Yin L, Li J, Wang J, et al
    Bidirectional Crosstalk between MAOA and AR Promotes Hormone-Dependent and Castration-Resistant Prostate Cancer.
    Cancer Res. 2021 Jun 24. pii: 0008-5472.CAN-21-0198.
    PubMed     Abstract available
    
    
    
79. HUANG Z, Tang B, Yang Y, Yang Z, et al
    MAP3K7-IKK inflammatory signaling modulates AR protein degradation and prostate cancer progression.
    Cancer Res. 2021 Jun 22. pii: 0008-5472.CAN-20-4194.
    PubMed     Abstract available
    
    
    
80. ENRIQUEZ C, Cancila V, Ferri R, Sulsenti R, et al
    Castration-induced down-regulation of SPARC in stromal cells drives neuroendocrine differentiation of prostate cancer.
    Cancer Res. 2021 Jun 21. pii: 0008-5472.CAN-21-0163.
    PubMed     Abstract available
    
    
    
81. SENA LA, Denmeade SR
    Fatty acid synthesis in prostate cancer: vulnerability or epiphenomenon?
    Cancer Res. 2021 Jun 18. pii: 0008-5472.CAN-21-1392.
    PubMed     Abstract available
    
    
    May 2021
82. OSMULSKI PA, Cunsolo A, Chen M, Qian Y, et al
    Contacts with macrophages promote an aggressive nanomechanical phenotype of circulating tumor cells in prostate cancer.
    Cancer Res. 2021 May 27. pii: 0008-5472.CAN-20-3595.
    PubMed     Abstract available
    
    
    
83. MATSUSHITA M, Fujita K, Hayashi T, Kayama H, et al
    Gut microbiota-derived short-chain fatty acids promote prostate cancer growth via IGF-1 signaling.
    Cancer Res. 2021 May 26. pii: 0008-5472.CAN-20-4090.
    PubMed     Abstract available
    
    
    
84. MARTINEZ RS, Salji MJ, Rushworth L, Ntala C, et al
    SLFN5 regulates LAT1-mediated mTOR activation in castration-resistant prostate cancer.
    Cancer Res. 2021 May 13. pii: 0008-5472.CAN-20-3694.
    PubMed     Abstract available
    
    
    
85. RAHMAN NIA, Sato A, Tsevelnorov K, Shimizu A, et al
    Stomatin-Mediated Inhibition of the Akt Signaling Axis Suppresses Tumor Growth.
    Cancer Res. 2021;81:2318-2331.
    PubMed     Abstract available
    
    
    
86. LIU Z, Guo C, Das SK, Yu X, et al
    Engineering T Cells to Express Tumoricidal MDA-7/IL24 Enhances Cancer Immunotherapy.
    Cancer Res. 2021;81:2429-2441.
    PubMed     Abstract available
    
    
    April 2021
87. MATTHIAS J, Engelhardt J, Schafer M, Bauder-Wust U, et al
    Cytoplasmic Localization of Prostate-Specific Membrane Antigen Inhibitors May Confer Advantages for Targeted Cancer Therapies.
    Cancer Res. 2021;81:2234-2245.
    PubMed     Abstract available
    
    
    
88. LACHANCE J
    Beyond Stamp Collecting: Evolutionary and Functional Genomics Advance Our Understanding of Cancer Biology.
    Cancer Res. 2021;81:1637-1638.
    PubMed     Abstract available
    
    
    March 2021
89. ZHOU Y, Jin X, Ma J, Ding D, et al
    HDAC5 Loss Impairs RB Repression of Pro-Oncogenic Genes and Confers CDK4/6 Inhibitor Resistance in Cancer.
    Cancer Res. 2021;81:1486-1499.
    PubMed     Abstract available
    
    
    February 2021
90. PASCHALIS A, Welti J, Neeb AJ, Yuan W, et al
    JMJD6 Is a Druggable Oxygenase That Regulates AR-V7 Expression in Prostate Cancer.
    Cancer Res. 2021;81:1087-1100.
    PubMed     Abstract available
    
    
    
91. STROBL MAR, West J, Viossat Y, Damaghi M, et al
    Turnover Modulates the Need for a Cost of Resistance in Adaptive Therapy.
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