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  Schizophrenia

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Articles published in Am J Psychiatry

Retrieve available abstracts of 71 articles:
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Single Articles


    November 2025
  1. KANTROWITZ JT, Mayer MR, Choo TH, Liu K, et al
    Effect Size Deflation With Increasing Sample Size in Adjunctive Trials for Negative Symptoms in Schizophrenia: A Meta-Analysis and Meta-Regression Across Mechanisms of Action.
    Am J Psychiatry. 2025 Nov 19:appiajp20250034. doi: 10.1176/appi.ajp.20250034.
    PubMed     Abstract available


  2. LANG U, Metsala J, Ramsay H, Boland F, et al
    Doxycycline Use in Adolescent Psychiatric Patients and Risk of Schizophrenia: An Emulated Target Trial.
    Am J Psychiatry. 2025 Nov 5:appiajp20240958. doi: 10.1176/appi.ajp.20240958.
    PubMed     Abstract available


  3. KALIN NH
    Schizophrenia, Alcohol Use Disorder, and Stimulant Use Disorder.
    Am J Psychiatry. 2025;182:957-959.
    PubMed    


  4. YALCINBAS EA, Ajanaku B, Nelson ED, Garcia-Flores R, et al
    Transcriptomic Analysis of the Human Habenula in Schizophrenia.
    Am J Psychiatry. 2025;182:991-1006.
    PubMed     Abstract available


  5. GUR RE
    Pathways to Psychosis: Factors Associated With Risk for Psychosis Spectrum Disorders.
    Am J Psychiatry. 2025;182:984-990.
    PubMed    


    October 2025
  6. ZHAO G, Sun Y, Zhang Y, Lu T, et al
    Efficacy and Tolerability of Seven Antipsychotic Drugs in Acutely Ill Patients With Schizophrenia: A Randomized, Multicenter, Assessor-Blinded Trial.
    Am J Psychiatry. 2025 Oct 29:appiajp20250111. doi: 10.1176/appi.ajp.20250111.
    PubMed     Abstract available


  7. HOWES OD, Bukala BR, Chen EYH, Correll CU, et al
    Relapse in Schizophrenia: A Systematic Review of Criteria for Clinical Studies and International Consensus Guidelines to Improve Them.
    Am J Psychiatry. 2025 Oct 8:appiajp20241040. doi: 10.1176/appi.ajp.20241040.
    PubMed     Abstract available


    September 2025
  8. KALIN NH
    Scientific Advances Relevant to Schizophrenia, Psychosis, and the Treatment of Methamphetamine Use Disorder.
    Am J Psychiatry. 2025;182:797-800.
    PubMed    


  9. HORAN WP, Harvey PD, Brannan SK
    Does Xanomeline/Trospium Have Unique Benefits for Cognitive Impairment Associated With Schizophrenia? Response to Tandon.
    Am J Psychiatry. 2025;182:878-879.
    PubMed    


  10. CASSIDY C, Wang Y, Abi-Dargham A
    Forging a Role for Iron in the Dopamine Dysfunction of Schizophrenia.
    Am J Psychiatry. 2025;182:804-806.
    PubMed    


  11. VANO LJ, McCutcheon RA, Sedlacik J, Kaar SJ, et al
    Reduced Brain Iron and Striatal Hyperdopaminergia in Schizophrenia: A Quantitative Susceptibility Mapping MRI and PET Study.
    Am J Psychiatry. 2025;182:830-839.
    PubMed     Abstract available


  12. TANDON R
    Does Xanomeline/Trospium Have Unique Benefits for Cognitive Impairment Associated With Schizophrenia?
    Am J Psychiatry. 2025;182:878.
    PubMed    


  13. ANGLIN DM, Olfson M, van der Ven E, Oh H, et al
    Neighborhood Social Vulnerability and Racial Disparities in Schizophrenia Spectrum Disorder Prevalence.
    Am J Psychiatry. 2025;182:850-860.
    PubMed     Abstract available


    July 2025
  14. AHN Y, Kim J, Jung K, Lee DJ, et al
    Relationship Between Problematic Alcohol Use and Various Psychiatric Disorders: A Genetically Informed Study.
    Am J Psychiatry. 2025;182:671-682.
    PubMed     Abstract available


    June 2025
  15. WARD HB, Beermann A, Manzanarez Felix K, Narisetti L, et al
    Grip Strength as a Marker of Resting-State Network Integrity and Well-Being in Early Psychosis.
    Am J Psychiatry. 2025 Jun 25:appiajp20240780. doi: 10.1176/appi.ajp.20240780.
    PubMed     Abstract available


  16. KALIN NH
    Depression, Inflammation, and Postpartum Psychosis.
    Am J Psychiatry. 2025;182:501-503.
    PubMed    


  17. DAZZAN P
    A Step Closer to Understanding Familial Risk for Postpartum Psychosis.
    Am J Psychiatry. 2025;182:504-505.
    PubMed    


    May 2025
  18. ZHANG L, Ivleva EI, Parker DA, Hill SK, et al
    Impact of Polygenic Interactions With Anticholinergic Burden on Cognition and Brain Structure in Psychosis Spectrum Disorders.
    Am J Psychiatry. 2025 May 28:appiajp20240709. doi: 10.1176/appi.ajp.20240709.
    PubMed     Abstract available


  19. KEPINSKA AP, Robakis TK, Humphreys K, Liu X, et al
    Familial Risk of Postpartum Psychosis.
    Am J Psychiatry. 2025 May 19:appiajp20230576. doi: 10.1176/appi.ajp.20230576.
    PubMed     Abstract available


    April 2025
  20. CHENGAPPA KNR, Gannon JM, Joshi YB
    A Call to Psychiatrists: Deprescription of Unnecessary Anticholinergic Medications in Schizophrenia Must Start Now.
    Am J Psychiatry. 2025;182:319-321.
    PubMed    


  21. PERLIS RH
    Targeting Schizophrenia.
    Am J Psychiatry. 2025;182:329-331.
    PubMed    


  22. ORHAN F, Malwade S, Khanlarkhani N, Gkogka A, et al
    Kynurenic Acid and Promotion of Activity-Dependent Synapse Elimination in Schizophrenia.
    Am J Psychiatry. 2025;182:389-400.
    PubMed     Abstract available


  23. ZHOU L, Sommer IEC, Yang P, Sikirin L, et al
    What Do Four Decades of Research Tell Us About the Association Between Childhood Adversity and Psychosis: An Updated and Extended Multi-Level Meta-Analysis.
    Am J Psychiatry. 2025;182:360-372.
    PubMed     Abstract available


  24. KALIN NH
    Psychotic Disorders and Schizophrenia: Treatment, Risk, Brain Alterations, and Mechanisms.
    Am J Psychiatry. 2025;182:313-315.
    PubMed    


  25. NEUFELD NH, Blumberger DM
    An Update on the Use of Neuromodulation Strategies in the Treatment of Schizophrenia.
    Am J Psychiatry. 2025;182:332-340.
    PubMed     Abstract available


    March 2025
  26. CORLETT PR, Fraser KM
    20 Years of Aberrant Salience in Psychosis: What Have We Learned?
    Am J Psychiatry. 2025 Mar 26:appiajp20240556. doi: 10.1176/appi.ajp.20240556.
    PubMed     Abstract available


  27. KALIN NH
    New Developments in the Treatment of Depression, OCD, and Schizophrenia.
    Am J Psychiatry. 2025;182:223-226.
    PubMed    


  28. JAVITT DC
    Xanomeline-Trospium Treatment of Cognitive Impairments of Schizophrenia: Hope for Some, or Hope for All?
    Am J Psychiatry. 2025;182:237-239.
    PubMed    


    February 2025
  29. OMLOR W, Rabe F, Fuchs S, Surbeck W, et al
    Estimating Multimodal Structural Brain Variability in Schizophrenia Spectrum Disorders: A Worldwide ENIGMA Study.
    Am J Psychiatry. 2025 Feb 26:appiajp20230806. doi: 10.1176/appi.ajp.20230806.
    PubMed     Abstract available


  30. MANCINI V, Latreche C, Fanshawe JB, Varvari I, et al
    Anticholinergic Burden and Cognitive Function in Psychosis: A Systematic Review and Meta-Analysis.
    Am J Psychiatry. 2025 Feb 26:appiajp20240260. doi: 10.1176/appi.ajp.20240260.
    PubMed     Abstract available


  31. TIIHONEN J, Tanskanen A, Solmi M, Rubio JM, et al
    Continuous Dopamine D(2) Receptor Blockade and Long-Term Outcome in First-Episode Schizophrenia.
    Am J Psychiatry. 2025 Feb 19:0. doi: 10.1176/appi.ajp.20240321.
    PubMed     Abstract available


    December 2024
  32. HORAN WP, Sauder C, Harvey PD, Ramsay IS, et al
    The Impact of Xanomeline and Trospium Chloride on Cognitive Impairment in Acute Schizophrenia: Replication in Pooled Data From Two Phase 3 Trials.
    Am J Psychiatry. 2024 Dec 11. doi: 10.1176/appi.ajp.20240076.
    PubMed     Abstract available


    October 2024
  33. GALLUCCI J, Yu JC, Oliver LD, Nakua H, et al
    Neural Circuitry and Therapeutic Targeting of Depressive Symptoms in Schizophrenia Spectrum Disorders.
    Am J Psychiatry. 2024;181:910-919.
    PubMed     Abstract available


  34. REILLY TJ, McCutcheon RA
    Menopausal Hormone Therapy for Women With Schizophrenia: What's Stopping Us?
    Am J Psychiatry. 2024;181:854-855.
    PubMed    


  35. KRAMER EN, Velicu V
    Aripiprazole Augmentation as a Treatment for Clozapine-Induced Weight Gain.
    Am J Psychiatry. 2024;181:935-936.
    PubMed    


  36. CHENGAPPA KNR, Cotes RO
    Clozapine's High Incidence of Ileus and Pneumonia Demand Better Clinical Strategies-How Do We Get There?
    Am J Psychiatry. 2024;181:851-853.
    PubMed    


  37. MCINTYRE RS, Kwan ATH, Rosenblat JD, Teopiz KM, et al
    Aripiprazole Augmentation as a Treatment for Clozapine-Induced Weight Gain: Response to Kramer and Velicu.
    Am J Psychiatry. 2024;181:936-937.
    PubMed    


  38. HWANG M, Brady R
    Neural Circuitry and Therapeutic Targeting of Depressive Symptoms in Schizophrenia Spectrum Disorders.
    Am J Psychiatry. 2024;181:858-860.
    PubMed    


  39. ARNSTEN AFT, Datta D
    Characterizing the Most Vulnerable Prefrontal Cortical Neurons in Schizophrenia.
    Am J Psychiatry. 2024;181:861-864.
    PubMed    


  40. TAMMINGA CA
    Psychosis Risk With Prescription Amphetamine.
    Am J Psychiatry. 2024;181:856-857.
    PubMed    


  41. KALIN NH
    Schizophrenia Spectrum Disorders and Psychosis.
    Am J Psychiatry. 2024;181:847-850.
    PubMed    


  42. LEUCHT S, Priller J, Davis JM
    Antipsychotic Drugs: A Concise Review of History, Classification, Indications, Mechanism, Efficacy, Side Effects, Dosing, and Clinical Application.
    Am J Psychiatry. 2024;181:865-878.
    PubMed     Abstract available


  43. ARION D, Enwright JF 3rd, Gonzalez-Burgos G, Lewis DA, et al
    Cell Type-Specific Profiles and Developmental Trajectories of Transcriptomes in Primate Prefrontal Layer 3 Pyramidal Neurons: Implications for Schizophrenia.
    Am J Psychiatry. 2024;181:920-934.
    PubMed     Abstract available


    September 2024
  44. PARTANEN JJ, Happola P, Kampe A, Ahola-Olli A, et al
    High Burden of Ileus and Pneumonia in Clozapine-Treated Individuals With Schizophrenia: A Finnish 25-Year Follow-Up Register Study.
    Am J Psychiatry. 2024 Sep 12:appiajp20230744. doi: 10.1176/appi.ajp.20230744.
    PubMed     Abstract available


  45. MORAN LV, Skinner JP, Shinn AK, Nielsen K, et al
    Risk of Incident Psychosis and Mania With Prescription Amphetamines.
    Am J Psychiatry. 2024 Sep 12:appiajp20230329. doi: 10.1176/appi.ajp.20230329.
    PubMed     Abstract available


  46. BRAND BA, Sommer IE, Gangadin SS, Tanskanen A, et al
    Real-World Effectiveness of Menopausal Hormone Therapy in Preventing Relapse in Women With Schizophrenia or Schizoaffective Disorder.
    Am J Psychiatry. 2024 Sep 12:appiajp20230850. doi: 10.1176/appi.ajp.20230850.
    PubMed     Abstract available


    July 2024
  47. JONSSON L, Horbeck E, Primerano A, Song J, et al
    Association of Occupational Dysfunction and Hospital Admissions With Different Polygenic Profiles in Bipolar Disorder.
    Am J Psychiatry. 2024;181:620-629.
    PubMed     Abstract available


    June 2024
  48. KURTZ MM
    Cognitive Remediation in Schizophrenia Spectrum Illness: Evidence for Treatment Persistence.
    Am J Psychiatry. 2024;181:471-473.
    PubMed    


  49. VANO LJ, Veronese M, McCutcheon RA, Howes OD, et al
    Neuromelanin-Sensitive MRI: A Biomarker for Treatment-Resistant Schizophrenia?
    Am J Psychiatry. 2024;181:468-470.
    PubMed    


  50. BRENNAND KJ
    Aligning Stem Cell Models and Postmortem Studies to Query Striatal Neurodevelopment in Schizophrenia.
    Am J Psychiatry. 2024;181:465-467.
    PubMed    


  51. BIRNBAUM R, Weinberger DR
    The Genesis of Schizophrenia: An Origin Story.
    Am J Psychiatry. 2024;181:482-492.
    PubMed     Abstract available


  52. KALIN NH
    Advances in Understanding Schizophrenia, ADHD, and ASD.
    Am J Psychiatry. 2024;181:461-464.
    PubMed    


  53. TRAMAZZO S, Lian W, Ajnakina O, Carlson G, et al
    Long-Term Course of Remission and Recovery in Psychotic Disorders.
    Am J Psychiatry. 2024;181:532-540.
    PubMed     Abstract available


    May 2024
  54. KANG J, Castro VM, Ripperger M, Venkatesh S, et al
    Genome-Wide Association Study of Treatment-Resistant Depression: Shared Biology With Metabolic Traits.
    Am J Psychiatry. 2024 May 15:appiajp20230247. doi: 10.1176/appi.ajp.20230247.
    PubMed     Abstract available


    April 2024
  55. LIGHT GA, Swerdlow NR
    Predicting Conversion to Psychosis: What Lies Beyond the Biomarkers?
    Am J Psychiatry. 2024;181:272-274.
    PubMed    


    March 2024
  56. VAN DER PLUIJM M, Wengler K, Reijers PN, Cassidy CM, et al
    Neuromelanin-Sensitive MRI as Candidate Marker for Treatment Resistance in First-Episode Schizophrenia.
    Am J Psychiatry. 2024 Mar 13:appiajp20220780. doi: 10.1176/appi.ajp.20220780.
    PubMed     Abstract available


  57. VITA A, Barlati S, Ceraso A, Nibbio G, et al
    Durability of Effects of Cognitive Remediation on Cognition and Psychosocial Functioning in Schizophrenia: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
    Am J Psychiatry. 2024 Mar 13:appiajp20230396. doi: 10.1176/appi.ajp.20230396.
    PubMed     Abstract available


    February 2024
  58. HOU Y, Xia H, He T, Zhang B, et al
    N2 Responses in Youths With Psychosis Risk Syndrome and Their Association With Clinical Outcomes: A Cohort Follow-Up Study Based on the Three-Stimulus Visual Oddball Paradigm.
    Am J Psychiatry. 2024 Feb 29:appiajp20221013. doi: 10.1176/appi.ajp.20221013.
    PubMed     Abstract available


  59. ROGNLI EB, Hoye A, Bramness JG
    Methamphetamine-Induced Psychosis and Schizophrenia: A Call for Special Attention: Response to Zhu et al.
    Am J Psychiatry. 2024;181:168-169.
    PubMed    


  60. ZHU L, Ni T, Guan F
    Methamphetamine-Induced Psychosis and Schizophrenia: A Call for Special Attention.
    Am J Psychiatry. 2024;181:168.
    PubMed    


    November 2023
  61. SAWADA T, Barbosa AR, Araujo B, McCord AE, et al
    Recapitulation of Perturbed Striatal Gene Expression Dynamics of Donor's Brains With Ventral Forebrain Organoids Derived From the Same Individuals With Schizophrenia.
    Am J Psychiatry. 2023 Nov 2:appiajp20220723. doi: 10.1176/appi.ajp.20220723.
    PubMed     Abstract available


  62. KALIN NH
    New Insights Into Psychotic Disorders.
    Am J Psychiatry. 2023;180:779-781.
    PubMed    


  63. VAN DER VEN E, Susser E
    Structural Racism and Risk of Schizophrenia.
    Am J Psychiatry. 2023;180:782-784.
    PubMed    


  64. CANNON TD
    Predicting Conversion to Psychosis Using Machine Learning: Are We There Yet?
    Am J Psychiatry. 2023;180:789-791.
    PubMed    


  65. GOFF DC, Roffman J, Holt DJ
    Another Step Toward the Prediction of Antipsychotic Treatment Response Using Functional Connectivity.
    Am J Psychiatry. 2023;180:787-788.
    PubMed    


  66. FORSYTH JK, Bearden CE
    Rethinking the First Episode of Schizophrenia: Identifying Convergent Mechanisms During Development and Moving Toward Prediction.
    Am J Psychiatry. 2023;180:792-804.
    PubMed    


  67. STRAWBRIDGE RJ, Graham N
    Dissecting the Genetic Relationship Between Schizophrenia and Cardiovascular Disease.
    Am J Psychiatry. 2023;180:785-786.
    PubMed    


  68. JOSHI Y, Swerdlow N, Light G
    Points that Need Attention in Early Auditory Information Processing Research in Schizophrenia: Response to Lin and Hsieh.
    Am J Psychiatry. 2023;180:841-842.
    PubMed    


    October 2023
  69. SMUCNY J, Davidson I, Carter CS
    Are We There Yet? Predicting Conversion to Psychosis Using Machine Learning.
    Am J Psychiatry. 2023 Oct 4:appiajp20220973. doi: 10.1176/appi.ajp.20220973.
    PubMed    


    September 2023
  70. RODEVAND L, Rahman Z, Hindley GFL, Smeland OB, et al
    Characterizing the Shared Genetic Underpinnings of Schizophrenia and Cardiovascular Disease Risk Factors.
    Am J Psychiatry. 2023 Sep 27:appiajp20220660. doi: 10.1176/appi.ajp.20220660.
    PubMed     Abstract available


  71. KUMAR K, Modenato C, Moreau C, Ching CRK, et al
    Subcortical Brain Alterations in Carriers of Genomic Copy Number Variants.
    Am J Psychiatry. 2023;180:685-698.
    PubMed     Abstract available


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