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Articles published in Mol Psychiatry

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Single Articles


    March 2019
  1. DEMICHELE-SWEET MAA, Weamer EA, Klei L, Vrana DT, et al
    Correction: Genetic risk for schizophrenia and psychosis in Alzheimer disease.
    Mol Psychiatry. 2019 Mar 12. pii: 10.1038/s41380-019-0373.
    PubMed     Text format     Abstract available


  2. ORLOVSKA-WAAST S, Kohler-Forsberg O, Brix SW, Nordentoft M, et al
    Correction: Cerebrospinal fluid markers of inflammation and infections in schizophrenia and affective disorders: a systematic review and meta-analysis.
    Mol Psychiatry. 2019 Mar 12. pii: 10.1038/s41380-019-0381.
    PubMed     Text format     Abstract available


    February 2019
  3. COLIZZI M, Weltens N, McGuire P, Lythgoe D, et al
    Delta-9-tetrahydrocannabinol increases striatal glutamate levels in healthy individuals: implications for psychosis.
    Mol Psychiatry. 2019 Feb 15. pii: 10.1038/s41380-019-0374.
    PubMed     Text format     Abstract available


  4. ROALF DR, de la Garza AG, Rosen A, Calkins ME, et al
    Alterations in white matter microstructure in individuals at persistent risk for psychosis.
    Mol Psychiatry. 2019 Feb 5. pii: 10.1038/s41380-019-0360.
    PubMed     Text format     Abstract available


    January 2019
  5. HADAR R, Winter R, Edemann-Callesen H, Wieske F, et al
    Prevention of schizophrenia deficits via non-invasive adolescent frontal cortex stimulation in rats.
    Mol Psychiatry. 2019 Jan 28. pii: 10.1038/s41380-019-0356.
    PubMed     Text format     Abstract available


  6. SCOTT MR, Meador-Woodruff JH
    Intracellular compartment-specific proteasome dysfunction in postmortem cortex in schizophrenia subjects.
    Mol Psychiatry. 2019 Jan 25. pii: 10.1038/s41380-019-0359.
    PubMed     Text format     Abstract available


  7. WARLAND A, Kendall KM, Rees E, Kirov G, et al
    Schizophrenia-associated genomic copy number variants and subcortical brain volumes in the UK Biobank.
    Mol Psychiatry. 2019 Jan 24. pii: 10.1038/s41380-019-0355.
    PubMed     Text format     Abstract available


  8. MA L, Semick SA, Chen Q, Li C, et al
    Schizophrenia risk variants influence multiple classes of transcripts of sorting nexin 19 (SNX19).
    Mol Psychiatry. 2019 Jan 11. pii: 10.1038/s41380-018-0293.
    PubMed     Text format     Abstract available


  9. AMARE AT, Vaez A, Hsu YH, Direk N, et al
    Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression.
    Mol Psychiatry. 2019 Jan 9. pii: 10.1038/s41380-018-0336.
    PubMed     Text format     Abstract available


  10. ESCOTT-PRICE V, Bracher-Smith M, Menzies G, Walters J, et al
    Genetic liability to schizophrenia is negatively associated with educational attainment in UK Biobank.
    Mol Psychiatry. 2019 Jan 4. pii: 10.1038/s41380-018-0328.
    PubMed     Text format    


  11. SMELAND OB, Bahrami S, Frei O, Shadrin A, et al
    Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence.
    Mol Psychiatry. 2019 Jan 4. pii: 10.1038/s41380-018-0332.
    PubMed     Text format     Abstract available


    December 2018
  12. BERGMAN O, Karry R, Milhem J, Ben-Shachar D, et al
    NDUFV2 pseudogene (NDUFV2P1) contributes to mitochondrial complex I deficits in schizophrenia.
    Mol Psychiatry. 2018 Dec 10. pii: 10.1038/s41380-018-0309.
    PubMed     Text format     Abstract available


  13. REAY WR, Atkins JR, Quide Y, Carr VJ, et al
    Polygenic disruption of retinoid signalling in schizophrenia and a severe cognitive deficit subtype.
    Mol Psychiatry. 2018 Dec 7. pii: 10.1038/s41380-018-0305.
    PubMed     Text format     Abstract available


    November 2018
  14. RADULESCU E, Jaffe AE, Straub RE, Chen Q, et al
    Identification and prioritization of gene sets associated with schizophrenia risk by co-expression network analysis in human brain.
    Mol Psychiatry. 2018 Nov 26. pii: 10.1038/s41380-018-0304.
    PubMed     Text format     Abstract available


  15. COLLIN G, Seidman LJ, Keshavan MS, Stone WS, et al
    Functional connectome organization predicts conversion to psychosis in clinical high-risk youth from the SHARP program.
    Mol Psychiatry. 2018 Nov 8. pii: 10.1038/s41380-018-0288.
    PubMed     Text format     Abstract available


    October 2018
  16. PILLINGER T, D'Ambrosio E, McCutcheon R, Howes OD, et al
    Correction to: Is psychosis a multisystem disorder? A meta-review of central nervous system, immune, cardiometabolic, and endocrine alterations in first-episode psychosis and perspective on potential models.
    Mol Psychiatry. 2018 Oct 18. pii: 10.1038/s41380-018-0275.
    PubMed     Text format     Abstract available


  17. DOUCET GE, Moser DA, Luber MJ, Leibu E, et al
    Baseline brain structural and functional predictors of clinical outcome in the early course of schizophrenia.
    Mol Psychiatry. 2018 Oct 3. pii: 10.1038/s41380-018-0269.
    PubMed     Text format     Abstract available


    September 2018
  18. GUO JY, Ragland JD, Carter CS
    Memory and cognition in schizophrenia.
    Mol Psychiatry. 2018 Sep 21. pii: 10.1038/s41380-018-0231.
    PubMed     Text format     Abstract available


  19. WANG HY, MacDonald ML, Borgmann-Winter KE, Banerjee A, et al
    mGluR5 hypofunction is integral to glutamatergic dysregulation in schizophrenia.
    Mol Psychiatry. 2018 Sep 13. pii: 10.1038/s41380-018-0234.
    PubMed     Text format     Abstract available


  20. CAI HQ, Catts VS, Webster MJ, Galletly C, et al
    Increased macrophages and changed brain endothelial cell gene expression in the frontal cortex of people with schizophrenia displaying inflammation.
    Mol Psychiatry. 2018 Sep 13. pii: 10.1038/s41380-018-0235.
    PubMed     Text format     Abstract available


    August 2018
  21. ORLOVSKA-WAAST S, Kohler-Forsberg O, Brix SW, Nordentoft M, et al
    Cerebrospinal fluid markers of inflammation and infections in schizophrenia and affective disorders: a systematic review and meta-analysis.
    Mol Psychiatry. 2018 Aug 16. pii: 10.1038/s41380-018-0220.
    PubMed     Text format     Abstract available


    July 2018
  22. SEGEV A, Yanagi M, Scott D, Southcott SA, et al
    Reduced GluN1 in mouse dentate gyrus is associated with CA3 hyperactivity and psychosis-like behaviors.
    Mol Psychiatry. 2018 Jul 23. pii: 10.1038/s41380-018-0124.
    PubMed     Text format     Abstract available


    June 2018
  23. KUMAR J, Liddle EB, Fernandes CC, Palaniyappan L, et al
    Glutathione and glutamate in schizophrenia: a 7T MRS study.
    Mol Psychiatry. 2018 Jun 22. pii: 10.1038/s41380-018-0104.
    PubMed     Text format     Abstract available


  24. CAO B, Cho RY, Chen D, Xiu M, et al
    Treatment response prediction and individualized identification of first-episode drug-naive schizophrenia using brain functional connectivity.
    Mol Psychiatry. 2018 Jun 19. pii: 10.1038/s41380-018-0106.
    PubMed     Text format     Abstract available


  25. SUN D, Ching CRK, Lin A, Forsyth JK, et al
    Large-scale mapping of cortical alterations in 22q11.2 deletion syndrome: Convergence with idiopathic psychosis and effects of deletion size.
    Mol Psychiatry. 2018 Jun 13. pii: 10.1038/s41380-018-0078.
    PubMed     Text format     Abstract available


  26. CHAUMETTE B, Ferrafiat V, Ambalavanan A, Goldenberg A, et al
    Missense variants in ATP1A3 and FXYD gene family are associated with childhood-onset schizophrenia.
    Mol Psychiatry. 2018 Jun 12. pii: 10.1038/s41380-018-0103.
    PubMed     Text format     Abstract available


  27. EGERTON A, Broberg BV, Van Haren N, Merritt K, et al
    Response to initial antipsychotic treatment in first episode psychosis is related to anterior cingulate glutamate levels: a multicentre (1)H-MRS study (OPTiMiSE).
    Mol Psychiatry. 2018 Jun 7. pii: 10.1038/s41380-018-0082.
    PubMed     Text format     Abstract available


    May 2018
  28. PILLINGER T, D'Ambrosio E, McCutcheon R, D Howes O, et al
    Is psychosis a multisystem disorder? A meta-review of central nervous system, immune, cardiometabolic, and endocrine alterations in first-episode psychosis and perspective on potential models.
    Mol Psychiatry. 2018 May 9. pii: 10.1038/s41380-018-0058.
    PubMed     Text format     Abstract available


  29. HAUBERG ME, Fullard JF, Zhu L, Cohain AT, et al
    Differential activity of transcribed enhancers in the prefrontal cortex of 537 cases with schizophrenia and controls.
    Mol Psychiatry. 2018 May 8. pii: 10.1038/s41380-018-0059.
    PubMed     Text format     Abstract available


    April 2018
  30. JAUHAR S, Veronese M, Nour MM, Rogdaki M, et al
    Determinants of treatment response in first-episode psychosis: an (18)F-DOPA PET study.
    Mol Psychiatry. 2018 Apr 20. pii: 10.1038/s41380-018-0042.
    PubMed     Text format     Abstract available


    March 2018
  31. CHOUINARD VA, Henderson DC, Dalla Man C, Valeri L, et al
    Impaired insulin signaling in unaffected siblings and patients with first-episode psychosis.
    Mol Psychiatry. 2018 Mar 9. pii: 10.1038/s41380-018-0045.
    PubMed     Text format     Abstract available


  32. OSIMO EF, Beck K, Reis Marques T, Howes OD, et al
    Synaptic loss in schizophrenia: a meta-analysis and systematic review of synaptic protein and mRNA measures.
    Mol Psychiatry. 2018 Mar 6. pii: 10.1038/s41380-018-0041.
    PubMed     Text format     Abstract available


  33. SULLIVAN CR, Koene RH, Hasselfeld K, O'Donovan SM, et al
    Neuron-specific deficits of bioenergetic processes in the dorsolateral prefrontal cortex in schizophrenia.
    Mol Psychiatry. 2018 Mar 1. pii: 10.1038/s41380-018-0035.
    PubMed     Text format     Abstract available


    February 2018
  34. KIM DD, Barr AM, Honer WG, Procyshyn RM, et al
    Exercise-induced hippocampal neurogenesis: 5-HT3 receptor antagonism by antipsychotics as a potential limiting factor in Schizophrenia.
    Mol Psychiatry. 2018 Feb 8. pii: 10.1038/s41380-018-0022.
    PubMed     Text format    


  35. ZILHAO NR, Abdellaoui A, Smit DJA, Cath DC, et al
    Polygenic prediction of obsessive compulsive symptoms.
    Mol Psychiatry. 2018;23:168-169.
    PubMed     Text format    


  36. PAGE SC, Hamersky GR, Gallo RA, Rannals MD, et al
    The schizophrenia- and autism-associated gene, transcription factor 4 regulates the columnar distribution of layer 2/3 prefrontal pyramidal neurons in an activity-dependent manner.
    Mol Psychiatry. 2018;23:304-315.
    PubMed     Text format     Abstract available


  37. ROFFMAN JL, Petruzzi LJ, Tanner AS, Brown HE, et al
    Biochemical, physiological and clinical effects of l-methylfolate in schizophrenia: a randomized controlled trial.
    Mol Psychiatry. 2018;23:316-322.
    PubMed     Text format     Abstract available


  38. NOTTER T, Coughlin JM, Gschwind T, Weber-Stadlbauer U, et al
    Translational evaluation of translocator protein as a marker of neuroinflammation in schizophrenia.
    Mol Psychiatry. 2018;23:323-334.
    PubMed     Text format     Abstract available


  39. ST POURCAIN B, Robinson EB, Anttila V, Sullivan BB, et al
    ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties.
    Mol Psychiatry. 2018;23:263-270.
    PubMed     Text format     Abstract available


  40. EHRENREICH H, Mitjans M, Van der Auwera S, Centeno TP, et al
    OTTO: a new strategy to extract mental disease-relevant combinations of GWAS hits from individuals.
    Mol Psychiatry. 2018;23:476-486.
    PubMed     Text format     Abstract available


  41. SCARR E, Udawela M, Thomas EA, Dean B, et al
    Changed gene expression in subjects with schizophrenia and low cortical muscarinic M1 receptors predicts disrupted upstream pathways interacting with that receptor.
    Mol Psychiatry. 2018;23:295-303.
    PubMed     Text format     Abstract available


  42. XU J, Hartley BJ, Kurup P, Phillips A, et al
    Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models.
    Mol Psychiatry. 2018;23:271-281.
    PubMed     Text format     Abstract available


    January 2018
  43. LIEBERMAN JA, Girgis RR, Brucato G, Moore H, et al
    Hippocampal dysfunction in the pathophysiology of schizophrenia: a selective review and hypothesis for early detection and intervention.
    Mol Psychiatry. 2018 Jan 9. pii: mp2017249. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


  44. DE VRIJ FM, Bouwkamp CG, Gunhanlar N, Shpak G, et al
    Candidate CSPG4 mutations and induced pluripotent stem cell modeling implicate oligodendrocyte progenitor cell dysfunction in familial schizophrenia.
    Mol Psychiatry. 2018 Jan 4. pii: 10.1038/s41380-017-0004.
    PubMed     Text format     Abstract available


  45. MITCHELL AC, Javidfar B, Pothula V, Ibi D, et al
    MEF2C transcription factor is associated with the genetic and epigenetic risk architecture of schizophrenia and improves cognition in mice.
    Mol Psychiatry. 2018;23:123-132.
    PubMed     Text format     Abstract available


    November 2017
  46. STEULLET P, Cabungcal JH, Bukhari SA, Ardelt MI, et al
    The thalamic reticular nucleus in schizophrenia and bipolar disorder: role of parvalbumin-expressing neuron networks and oxidative stress.
    Mol Psychiatry. 2017 Nov 28. pii: mp2017230. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


  47. CHENG CM, Chang WH, Chen MH, Tsai CF, et al
    Co-aggregation of major psychiatric disorders in individuals with first-degree relatives with schizophrenia: a nationwide population-based study.
    Mol Psychiatry. 2017 Nov 7. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


  48. ENWRIGHT III JF, Huo Z, Arion D, Corradi JP, et al
    Transcriptome alterations of prefrontal cortical parvalbumin neurons in schizophrenia.
    Mol Psychiatry. 2017 Nov 7. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


  49. KENDLER KS
    The genealogy of major depression: symptoms and signs of melancholia from 1880 to 1900.
    Mol Psychiatry. 2017;22:1539-1553.
    PubMed     Text format     Abstract available


    October 2017
  50. KELLY S, Jahanshad N, Zalesky A, Kochunov P, et al
    Widespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group.
    Mol Psychiatry. 2017 Oct 17. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


  51. GREENE C, Kealy J, Humphries MM, Gong Y, et al
    Dose-dependent expression of claudin-5 is a modifying factor in schizophrenia.
    Mol Psychiatry. 2017 Oct 10. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


  52. LEGGE SE, Hamshere ML, Ripke S, Pardinas AF, et al
    Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia.
    Mol Psychiatry. 2017;22:1502-1508.
    PubMed     Text format     Abstract available


    September 2017
  53. ZHOU Y, Dong F, Lanz TA, Reinhart V, et al
    Interactome analysis reveals ZNF804A, a schizophrenia risk gene, as a novel component of protein translational machinery critical for embryonic neurodevelopment.
    Mol Psychiatry. 2017 Sep 19. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


  54. SOLIMAN MA, Aboharb F, Zeltner N, Studer L, et al
    Pluripotent stem cells in neuropsychiatric disorders.
    Mol Psychiatry. 2017;22:1241-1249.
    PubMed     Text format     Abstract available


    August 2017
  55. ALACHKAR A, Wang L, Yoshimura R, Hamzeh AR, et al
    Prenatal one-carbon metabolism dysregulation programs schizophrenia-like deficits.
    Mol Psychiatry. 2017 Aug 15. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


  56. GUR RE, Bassett AS, McDonald-McGinn DM, Bearden CE, et al
    A neurogenetic model for the study of schizophrenia spectrum disorders: the International 22q11.2 Deletion Syndrome Brain Behavior Consortium.
    Mol Psychiatry. 2017 Aug 1. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


  57. NIMGAONKAR VL, Prasad KM, Chowdari KV, Severance EG, et al
    The complement system: a gateway to gene-environment interactions in schizophrenia pathogenesis.
    Mol Psychiatry. 2017 Aug 1. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


    July 2017
  58. WEINSTEIN JJ, van de Giessen E, Rosengard RJ, Xu X, et al
    PET imaging of dopamine-D2 receptor internalization in schizophrenia.
    Mol Psychiatry. 2017 Jul 25. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


  59. BENAMER N, Marti F, Lujan R, Hepp R, et al
    GluD1, linked to schizophrenia, controls the burst firing of dopamine neurons.
    Mol Psychiatry. 2017 Jul 11. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


  60. RAO AR, Yourshaw M, Christensen B, Nelson SF, et al
    Rare deleterious mutations are associated with disease in bipolar disorder families.
    Mol Psychiatry. 2017;22:1009-1014.
    PubMed     Text format     Abstract available


    June 2017
  61. TENG S, Thomson PA, McCarthy S, Kramer M, et al
    Rare disruptive variants in the DISC1 Interactome and Regulome: association with cognitive ability and schizophrenia.
    Mol Psychiatry. 2017 Jun 20. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


    May 2017
  62. KIM Y, Giusti-Rodriguez P, Crowley JJ, Bryois J, et al
    Comparative genomic evidence for the involvement of schizophrenia risk genes in antipsychotic effects.
    Mol Psychiatry. 2017 May 30. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


  63. WEINSTEIN JJ, van de Giessen E, Rosengard RJ, Xu X, et al
    PET imaging of dopamine-D2 receptor internalization in schizophrenia.
    Mol Psychiatry. 2017 May 16. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


  64. MOBERGET T, Doan NT, Alnaes D, Kaufmann T, et al
    Cerebellar volume and cerebellocerebral structural covariance in schizophrenia: a multisite mega-analysis of 983 patients and 1349 healthy controls.
    Mol Psychiatry. 2017 May 16. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


  65. BIRNBAUM R, Jaffe AE, Chen Q, Shin JH, et al
    Investigating the neuroimmunogenic architecture of schizophrenia.
    Mol Psychiatry. 2017 May 9. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


  66. TAO R, Davis KN, Li C, Shin JH, et al
    GAD1 alternative transcripts and DNA methylation in human prefrontal cortex and hippocampus in brain development, schizophrenia.
    Mol Psychiatry. 2017 May 9. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


  67. DEMICHELE-SWEET MAA, Weamer EA, Klei L, Vrana DT, et al
    Genetic risk for schizophrenia and psychosis in Alzheimer disease.
    Mol Psychiatry. 2017 May 2. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


    April 2017
  68. DUNCAN LE, Ratanatharathorn A, Aiello AE, Almli LM, et al
    Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability.
    Mol Psychiatry. 2017 Apr 25. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


  69. HADAR R, Bikovski L, Soto-Montenegro ML, Schimke J, et al
    Early neuromodulation prevents the development of brain and behavioral abnormalities in a rodent model of schizophrenia.
    Mol Psychiatry. 2017 Apr 4. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


    March 2017
  70. NOTTER T, Meyer U
    Microglia and schizophrenia: where next?
    Mol Psychiatry. 2017 Mar 28. doi: 10.1038/mp.2017.
    PubMed     Text format    


  71. PARKER KL, Kim YC, Kelley RM, Nessler AJ, et al
    Delta-frequency stimulation of cerebellar projections can compensate for schizophrenia-related medial frontal dysfunction.
    Mol Psychiatry. 2017 Mar 28. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


  72. LYALL AE, Pasternak O, Robinson DG, Newell D, et al
    Greater extracellular free-water in first-episode psychosis predicts better neurocognitive functioning.
    Mol Psychiatry. 2017 Mar 28. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


  73. DEVOR A, Andreassen OA, Wang Y, Maki-Marttunen T, et al
    Genetic evidence for role of integration of fast and slow neurotransmission in schizophrenia.
    Mol Psychiatry. 2017 Mar 28. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


  74. STEULLET P, Cabungcal JH, Coyle J, Didriksen M, et al
    Oxidative stress-driven parvalbumin interneuron impairment as a common mechanism in models of schizophrenia.
    Mol Psychiatry. 2017 Mar 21. doi: 10.1038/mp.2017.
    PubMed     Text format     Abstract available


  75. WESSELING H, Xu B, Want EJ, Holmes E, et al
    System-based proteomic and metabonomic analysis of the Df(16)A+/- mouse identifies potential miR-185 targets and molecular pathway alterations.
    Mol Psychiatry. 2017;22:384-395.
    PubMed     Text format     Abstract available


    January 2017
  76. WEBER-STADLBAUER U, Richetto J, Labouesse MA, Bohacek J, et al
    Transgenerational transmission and modification of pathological traits induced by prenatal immune activation.
    Mol Psychiatry. 2017;22:102-112.
    PubMed     Text format     Abstract available


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