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  Schizophrenia

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Articles published in Mol Psychiatry

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Single Articles


    April 2024
  1. SUPEKAR K, de Los Angeles C, Ryali S, Kushan L, et al
    Robust and replicable functional brain signatures of 22q11.2 deletion syndrome and associated psychosis: a deep neural network-based multi-cohort study.
    Mol Psychiatry. 2024 Apr 12. doi: 10.1038/s41380-024-02495.
    PubMed     Abstract available


  2. TOTZEK JF, Chakravarty MM, Joober R, Malla A, et al
    Longitudinal inference of multiscale markers in psychosis: from hippocampal centrality to functional outcome.
    Mol Psychiatry. 2024 Apr 11. doi: 10.1038/s41380-024-02549.
    PubMed     Abstract available


    March 2024
  3. CHEN S, Tan Y, Tian L
    Immunophenotypes in psychosis: is it a premature inflamm-aging disorder?
    Mol Psychiatry. 2024 Mar 26. doi: 10.1038/s41380-024-02539.
    PubMed     Abstract available


  4. KOSKUVI M, Porsti E, Hewitt T, Rasanen N, et al
    Genetic contribution to microglial activation in schizophrenia.
    Mol Psychiatry. 2024 Mar 22. doi: 10.1038/s41380-024-02529.
    PubMed     Abstract available


  5. TESFAYE M, Spindola LM, Stavrum AK, Shadrin A, et al
    Sex effects on DNA methylation affect discovery in epigenome-wide association study of schizophrenia.
    Mol Psychiatry. 2024 Mar 19. doi: 10.1038/s41380-024-02513.
    PubMed     Abstract available


  6. FEOLA B, Beermann A, Manzanarez Felix K, Coleman M, et al
    Data-driven, connectome-wide analysis identifies psychosis-specific brain correlates of fear and anxiety.
    Mol Psychiatry. 2024 Mar 19. doi: 10.1038/s41380-024-02512.
    PubMed     Abstract available


  7. BIGDELI TB, Barr PB, Rajeevan N, Graham DP, et al
    Correlates of suicidal behaviors and genetic risk among United States veterans with schizophrenia or bipolar I disorder.
    Mol Psychiatry. 2024 Mar 15. doi: 10.1038/s41380-024-02472.
    PubMed     Abstract available


  8. WARREN TL, Tubbs JD, Lesh TA, Corona MB, et al
    Association of neurotransmitter pathway polygenic risk with specific symptom profiles in psychosis.
    Mol Psychiatry. 2024 Mar 15. doi: 10.1038/s41380-024-02457.
    PubMed     Abstract available


    February 2024
  9. FOUNTOULAKIS KN, Tsapakis EM
    Neither serotonin disorder is at the core of depression nor dopamine at the core of schizophrenia; still these are biologically based mental disorders.
    Mol Psychiatry. 2024 Feb 19. doi: 10.1038/s41380-024-02458.
    PubMed    


  10. SONG J, Jonsson L, Lu Y, Bergen SE, et al
    Key subphenotypes of bipolar disorder are differentially associated with polygenic liabilities for bipolar disorder, schizophrenia, and major depressive disorder.
    Mol Psychiatry. 2024 Feb 14. doi: 10.1038/s41380-024-02448.
    PubMed     Abstract available


  11. BENRIMOH D, Dlugunovych V, Wright AC, Phalen P, et al
    Correction: On the proportion of patients who experience a prodrome prior to psychosis onset: a systematic review and meta-analysis.
    Mol Psychiatry. 2024 Feb 14. doi: 10.1038/s41380-024-02481.
    PubMed    


  12. KOTOV R, Carpenter WT, Cicero DC, Correll CU, et al
    Psychosis superspectrum II: neurobiology, treatment, and implications.
    Mol Psychiatry. 2024 Feb 14. doi: 10.1038/s41380-024-02410.
    PubMed     Abstract available


  13. ZHU Y, Maikusa N, Radua J, Samann PG, et al
    Using brain structural neuroimaging measures to predict psychosis onset for individuals at clinical high-risk.
    Mol Psychiatry. 2024 Feb 9. doi: 10.1038/s41380-024-02426.
    PubMed     Abstract available


  14. GEORGIADIS F, Lariviere S, Glahn D, Hong LE, et al
    Connectome architecture shapes large-scale cortical alterations in schizophrenia: a worldwide ENIGMA study.
    Mol Psychiatry. 2024 Feb 9. doi: 10.1038/s41380-024-02442.
    PubMed     Abstract available


  15. BENRIMOH D, Dlugunovych V, Wright AC, Phalen P, et al
    On the proportion of patients who experience a prodrome prior to psychosis onset: A systematic review and meta-analysis.
    Mol Psychiatry. 2024 Feb 2. doi: 10.1038/s41380-024-02415.
    PubMed     Abstract available


  16. PODVIN S, Jones J, Kang A, Goodman R, et al
    Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures.
    Mol Psychiatry. 2024 Feb 2. doi: 10.1038/s41380-024-02422.
    PubMed     Abstract available


    January 2024
  17. CHUNG Y, Dienel SJ, Belch MJ, Fish KN, et al
    Altered Rbfox1-Vamp1 pathway and prefrontal cortical dysfunction in schizophrenia.
    Mol Psychiatry. 2024 Jan 25. doi: 10.1038/s41380-024-02417.
    PubMed     Abstract available


  18. CHEN H, Lei Y, Li R, Xia X, et al
    Resting-state EEG dynamic functional connectivity distinguishes non-psychotic major depression, psychotic major depression and schizophrenia.
    Mol Psychiatry. 2024 Jan 24. doi: 10.1038/s41380-023-02395.
    PubMed     Abstract available


  19. DAVIES C, Martins D, Dipasquale O, McCutcheon RA, et al
    Connectome dysfunction in patients at clinical high risk for psychosis and modulation by oxytocin.
    Mol Psychiatry. 2024 Jan 19. doi: 10.1038/s41380-024-02406.
    PubMed     Abstract available


  20. WOLFF A, Northoff G
    Temporal imprecision of phase coherence in schizophrenia and psychosis-dynamic mechanisms and diagnostic marker.
    Mol Psychiatry. 2024 Jan 16. doi: 10.1038/s41380-023-02337.
    PubMed     Abstract available


  21. JONAS KG, Cannon TD, Docherty AR, Dwyer D, et al
    Psychosis superspectrum I: Nosology, etiology, and lifespan development.
    Mol Psychiatry. 2024 Jan 10. doi: 10.1038/s41380-023-02388.
    PubMed     Abstract available


  22. SI S, Bi A, Yu Z, See C, et al
    Mapping gray and white matter volume abnormalities in early-onset psychosis: an ENIGMA multicenter voxel-based morphometry study.
    Mol Psychiatry. 2024 Jan 10. doi: 10.1038/s41380-023-02343.
    PubMed     Abstract available


  23. RUBIO JM, Lencz T, Cao H, Kraguljac N, et al
    Replication of a neuroimaging biomarker for striatal dysfunction in psychosis.
    Mol Psychiatry. 2024 Jan 4. doi: 10.1038/s41380-023-02381.
    PubMed     Abstract available


    December 2023
  24. DONG P, Voloudakis G, Fullard JF, Hoffman GE, et al
    Convergence of the dysregulated regulome in schizophrenia with polygenic risk and evolutionarily constrained enhancers.
    Mol Psychiatry. 2023 Dec 25. doi: 10.1038/s41380-023-02370.
    PubMed     Abstract available


  25. KENDLER KS, Ohlsson H, Sundquist J, Sundquist K, et al
    The relationship between familial-genetic risk and pharmacological treatment in a Swedish national sample of patients with major depression, bipolar disorder, and schizophrenia.
    Mol Psychiatry. 2023 Dec 20. doi: 10.1038/s41380-023-02365.
    PubMed     Abstract available


  26. KOMATSU H, Onoguchi G, Silverstein SM, Jerotic S, et al
    Retina as a potential biomarker in schizophrenia spectrum disorders: a systematic review and meta-analysis of optical coherence tomography and electroretinography.
    Mol Psychiatry. 2023 Dec 11. doi: 10.1038/s41380-023-02340.
    PubMed     Abstract available


    November 2023
  27. NORTHOFF G, Daub J, Hirjak D
    Overcoming the translational crisis of contemporary psychiatry - converging phenomenological and spatiotemporal psychopathology.
    Mol Psychiatry. 2023;28:4492-4499.
    PubMed     Abstract available


    October 2023
  28. OWEN MJ, Legge SE, Rees E, Walters JTR, et al
    Genomic findings in schizophrenia and their implications.
    Mol Psychiatry. 2023 Oct 18. doi: 10.1038/s41380-023-02293.
    PubMed     Abstract available


  29. LESH TA, Iosif AM, Tanase C, Vlasova RM, et al
    Extracellular free water elevations are associated with brain volume and maternal cytokine response in a longitudinal nonhuman primate maternal immune activation model.
    Mol Psychiatry. 2023;28:4185-4194.
    PubMed     Abstract available


  30. ARNATKEVICIUTE A, Lemire M, Morrison C, Mooney M, et al
    Trans-ancestry meta-analysis of genome wide association studies of inhibitory control.
    Mol Psychiatry. 2023;28:4175-4184.
    PubMed     Abstract available


  31. RAVEN EP, Veraart J, Kievit RA, Genc S, et al
    In vivo evidence of microstructural hypo-connectivity of brain white matter in 22q11.2 deletion syndrome.
    Mol Psychiatry. 2023;28:4342-4352.
    PubMed     Abstract available


    September 2023
  32. ODKHUU S, Kim WS, Tsogt U, Shen J, et al
    Network biomarkers in recovered psychosis patients who discontinued antipsychotics.
    Mol Psychiatry. 2023 Sep 29. doi: 10.1038/s41380-023-02279.
    PubMed     Abstract available


  33. HARRISON PJ, Bannerman DM
    GRIN2A (NR2A): a gene contributing to glutamatergic involvement in schizophrenia.
    Mol Psychiatry. 2023 Sep 22. doi: 10.1038/s41380-023-02265.
    PubMed     Abstract available


  34. ZHOU J, Xia Y, Li M, Chen Y, et al
    A higher dysregulation burden of brain DNA methylation in female patients implicated in the sex bias of Schizophrenia.
    Mol Psychiatry. 2023 Sep 11. doi: 10.1038/s41380-023-02243.
    PubMed     Abstract available


  35. FLYNN LT, Gao WJ
    DNA methylation and the opposing NMDAR dysfunction in schizophrenia and major depression disorders: a converging model for the therapeutic effects of psychedelic compounds in the treatment of psychiatric illness.
    Mol Psychiatry. 2023 Sep 7. doi: 10.1038/s41380-023-02235.
    PubMed     Abstract available


  36. SOLMI M, Cortese S, Vita G, De Prisco M, et al
    An umbrella review of candidate predictors of response, remission, recovery, and relapse across mental disorders.
    Mol Psychiatry. 2023;28:3671-3687.
    PubMed     Abstract available


  37. MERRITT K, Luque Laguna P, Sethi A, Drakesmith M, et al
    The impact of cumulative obstetric complications and childhood trauma on brain volume in young people with psychotic experiences.
    Mol Psychiatry. 2023;28:3688-3697.
    PubMed     Abstract available


  38. WOOTTON O, Shadrin AA, Mohn C, Susser E, et al
    Genome-wide association study in 404,302 individuals identifies 7 significant loci for reaction time variability.
    Mol Psychiatry. 2023;28:4011-4019.
    PubMed     Abstract available


  39. CAMPBELL PD, Lee I, Thyme S, Granato M, et al
    Mitochondrial proteins encoded by the 22q11.2 neurodevelopmental locus regulate neural stem and progenitor cell proliferation.
    Mol Psychiatry. 2023;28:3769-3781.
    PubMed     Abstract available


    August 2023
  40. BANAJ N, Vecchio D, Piras F, De Rossi P, et al
    Cortical morphology in patients with the deficit and non-deficit syndrome of schizophrenia: a worldwide meta- and mega-analyses.
    Mol Psychiatry. 2023 Aug 29. doi: 10.1038/s41380-023-02221.
    PubMed     Abstract available


  41. SALEH Y, Jarratt-Barnham I, Petitet P, Fernandez-Egea E, et al
    Negative symptoms and cognitive impairment are associated with distinct motivational deficits in treatment resistant schizophrenia.
    Mol Psychiatry. 2023 Aug 25. doi: 10.1038/s41380-023-02232.
    PubMed     Abstract available


  42. LIU L, Qi X, Cheng S, Meng P, et al
    Epigenetic analysis suggests aberrant cerebellum brain aging in old-aged adults with autism spectrum disorder and schizophrenia.
    Mol Psychiatry. 2023 Aug 24. doi: 10.1038/s41380-023-02233.
    PubMed     Abstract available


  43. PORTER A, Fei S, Damme KSF, Nusslock R, et al
    A meta-analysis and systematic review of single vs. multimodal neuroimaging techniques in the classification of psychosis.
    Mol Psychiatry. 2023 Aug 10. doi: 10.1038/s41380-023-02195.
    PubMed     Abstract available


  44. NURMI EL, Laughlin CP, de Wit H, Palmer AA, et al
    Polygenic contributions to performance on the Balloon Analogue Risk Task.
    Mol Psychiatry. 2023;28:3524-3530.
    PubMed     Abstract available


  45. HETTEMA JM, van den Oord EJCG, Zhao M, Xie LY, et al
    Methylome-wide association study of anxiety disorders.
    Mol Psychiatry. 2023;28:3484-3492.
    PubMed     Abstract available


    July 2023
  46. MYRAN DT, Pugliese M, Roberts RL, Solmi M, et al
    Association between non-medical cannabis legalization and emergency department visits for cannabis-induced psychosis.
    Mol Psychiatry. 2023 Jul 27. doi: 10.1038/s41380-023-02185.
    PubMed     Abstract available


  47. SOLMI M, Seitidis G, Mavridis D, Correll CU, et al
    Incidence, prevalence, and global burden of schizophrenia - data, with critical appraisal, from the Global Burden of Disease (GBD) 2019.
    Mol Psychiatry. 2023 Jul 27. doi: 10.1038/s41380-023-02138.
    PubMed     Abstract available


  48. MOON SY, Park H, Lee W, Lee S, et al
    Magnetic resonance texture analysis reveals stagewise nonlinear alterations of the frontal gray matter in patients with early psychosis.
    Mol Psychiatry. 2023 Jul 27. doi: 10.1038/s41380-023-02163.
    PubMed     Abstract available


  49. FOND G, Falissard B, Nuss P, Collin C, et al
    How can we improve the care of patients with schizophrenia in the real-world? A population-based cohort study of 456,003 patients.
    Mol Psychiatry. 2023 Jul 21. doi: 10.1038/s41380-023-02154.
    PubMed     Abstract available


  50. BOYER L, Falissard B, Nuss P, Collin C, et al
    Real-world effectiveness of long-acting injectable antipsychotic treatments in a nationwide cohort of 12,373 patients with schizophrenia-spectrum disorders.
    Mol Psychiatry. 2023 Jul 21. doi: 10.1038/s41380-023-02175.
    PubMed     Abstract available


    June 2023
  51. MAHADEVAN AS, Cornblath EJ, Lydon-Staley DM, Zhou D, et al
    Alprazolam modulates persistence energy during emotion processing in first-degree relatives of individuals with schizophrenia: a network control study.
    Mol Psychiatry. 2023 Jun 23. doi: 10.1038/s41380-023-02121.
    PubMed     Abstract available


  52. SOLMI M, Soardo L, Kaur S, Azis M, et al
    Meta-analytic prevalence of comorbid mental disorders in individuals at clinical high risk of psychosis: the case for transdiagnostic assessment.
    Mol Psychiatry. 2023 Jun 9. doi: 10.1038/s41380-023-02029.
    PubMed     Abstract available


    May 2023
  53. YU Y, Fu Y, Yu Y, Tang M, et al
    Investigating the shared genetic architecture between schizophrenia and body mass index.
    Mol Psychiatry. 2023 May 18. doi: 10.1038/s41380-023-02104.
    PubMed     Abstract available


  54. LEVITT JJ, Zhang F, Vangel M, Nestor PG, et al
    The organization of frontostriatal brain wiring in non-affective early psychosis compared with healthy subjects using a novel diffusion imaging fiber cluster analysis.
    Mol Psychiatry. 2023 May 12. doi: 10.1038/s41380-023-02031.
    PubMed     Abstract available


  55. DWYER DB, Chand GB, Pigoni A, Khuntia A, et al
    Psychosis brain subtypes validated in first-episode cohorts and related to illness remission: results from the PHENOM consortium.
    Mol Psychiatry. 2023 May 5. doi: 10.1038/s41380-023-02069.
    PubMed     Abstract available


  56. LICINIO J, Wong ML
    Psychosis and autism spectrum disorder: a special issue of Molecular Psychiatry.
    Mol Psychiatry. 2023;28:1830-1832.
    PubMed    


    April 2023
  57. VAN DEN OORD EJCG, Xie LY, Zhao M, Campbell TL, et al
    Genes implicated by a methylome-wide schizophrenia study in neonatal blood show differential expression in adult brain samples.
    Mol Psychiatry. 2023 Apr 27. doi: 10.1038/s41380-023-02080.
    PubMed     Abstract available


  58. CETIN-KARAYUMAK S, Lyall AE, Di Biase MA, Seitz-Holland J, et al
    Characterization of the extracellular free water signal in schizophrenia using multi-site diffusion MRI harmonization.
    Mol Psychiatry. 2023 Apr 24. doi: 10.1038/s41380-023-02068.
    PubMed     Abstract available


  59. DE BARTOLOMEIS A, De Simone G, De Prisco M, Barone A, et al
    Insulin effects on core neurotransmitter pathways involved in schizophrenia neurobiology: a meta-analysis of preclinical studies. Implications for the treatment.
    Mol Psychiatry. 2023 Apr 21. doi: 10.1038/s41380-023-02065.
    PubMed     Abstract available


  60. ALAMEDA L, Liu Z, Sham PC, Aas M, et al
    Exploring the mediation of DNA methylation across the epigenome between childhood adversity and First Episode of Psychosis-findings from the EU-GEI study.
    Mol Psychiatry. 2023 Apr 17. doi: 10.1038/s41380-023-02044.
    PubMed     Abstract available


  61. MAYELI A, LaGoy AD, Smagula SF, Wilson JD, et al
    Shared and distinct abnormalities in sleep-wake patterns and their relationship with the negative symptoms of Schizophrenia Spectrum Disorder patients.
    Mol Psychiatry. 2023 Apr 14. doi: 10.1038/s41380-023-02050.
    PubMed     Abstract available


  62. HOWES OD, Onwordi EC
    The synaptic hypothesis of schizophrenia version III: a master mechanism.
    Mol Psychiatry. 2023 Apr 11. doi: 10.1038/s41380-023-02043.
    PubMed     Abstract available


  63. MCWHINNEY SR, Brosch K, Calhoun VD, Crespo-Facorro B, et al
    Correction: Obesity and brain structure in schizophrenia - ENIGMA study in 3021 individuals.
    Mol Psychiatry. 2023 Apr 4. doi: 10.1038/s41380-023-02055.
    PubMed    


  64. ZWIR I, Arnedo J, Mesa A, Del Val C, et al
    Temperament & Character account for brain functional connectivity at rest: A diathesis-stress model of functional dysregulation in psychosis.
    Mol Psychiatry. 2023 Apr 4. doi: 10.1038/s41380-023-02039.
    PubMed     Abstract available


  65. MOLLON J, Almasy L, Jacquemont S, Glahn DC, et al
    The contribution of copy number variants to psychiatric symptoms and cognitive ability.
    Mol Psychiatry. 2023;28:1480-1493.
    PubMed     Abstract available


    March 2023
  66. GIANGRECO B, Dwir D, Klauser P, Jenni R, et al
    Characterization of early psychosis patients carrying a genetic vulnerability to redox dysregulation: a computational analysis of mechanism-based gene expression profile in fibroblasts.
    Mol Psychiatry. 2023 Mar 31. doi: 10.1038/s41380-023-02034.
    PubMed     Abstract available


  67. RAMMOS A, Kirov G, Hubbard L, Walters JTR, et al
    Family-based analysis of the contribution of rare and common genetic variants to school performance in schizophrenia.
    Mol Psychiatry. 2023 Mar 13. doi: 10.1038/s41380-023-02013.
    PubMed     Abstract available


  68. FOND G, Vidal M, Joseph M, Etchecopar-Etchart D, et al
    Self-stigma in schizophrenia: a systematic review and meta-analysis of 37 studies from 25 high- and low-to-middle income countries.
    Mol Psychiatry. 2023 Mar 8. doi: 10.1038/s41380-023-02003.
    PubMed     Abstract available


  69. NAKAMURA T, Takata A
    The molecular pathology of schizophrenia: an overview of existing knowledge and new directions for future research.
    Mol Psychiatry. 2023 Mar 6. doi: 10.1038/s41380-023-02005.
    PubMed     Abstract available


  70. LIN JR, Zhao Y, Jabalameli MR, Nguyen N, et al
    Rare coding variants as risk modifiers of the 22q11.2 deletion implicate postnatal cortical development in syndromic schizophrenia.
    Mol Psychiatry. 2023 Mar 3. doi: 10.1038/s41380-023-02009.
    PubMed     Abstract available


  71. LICINIO J, Wong ML
    Advances in Molecular Psychiatry - March 2023: mitochondrial function, stress, neuroinflammation - bipolar disorder, psychosis, and Alzheimer's disease.
    Mol Psychiatry. 2023;28:968-971.
    PubMed    


  72. SAETHER LS, Ueland T, Haatveit B, Maglanoc LA, et al
    Inflammation and cognition in severe mental illness: patterns of covariation and subgroups.
    Mol Psychiatry. 2023;28:1284-1292.
    PubMed     Abstract available


    February 2023
  73. MERRITT K, McCutcheon RA, Aleman A, Ashley S, et al
    Variability and magnitude of brain glutamate levels in schizophrenia: a meta and mega-analysis.
    Mol Psychiatry. 2023 Feb 17. doi: 10.1038/s41380-023-01991.
    PubMed     Abstract available


  74. KOMATSU H, Onoguchi G, Jerotic S, Kanahara N, et al
    Correction: Retinal layers and associated clinical factors in schizophrenia spectrum disorders: a systematic review and meta-analysis.
    Mol Psychiatry. 2023 Feb 9. doi: 10.1038/s41380-023-01983.
    PubMed    


  75. LOTAN A, Luza S, Opazo CM, Ayton S, et al
    Perturbed iron biology in the prefrontal cortex of people with schizophrenia.
    Mol Psychiatry. 2023 Feb 7. doi: 10.1038/s41380-023-01979.
    PubMed     Abstract available


  76. MCCUTCHEON RA, Keefe RSE, McGuire PK
    Correction: Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment.
    Mol Psychiatry. 2023 Feb 2. doi: 10.1038/s41380-023-01984.
    PubMed    


  77. WANG M, Barker PB, Cascella NG, Coughlin JM, et al
    Longitudinal changes in brain metabolites in healthy controls and patients with first episode psychosis: a 7-Tesla MRS study.
    Mol Psychiatry. 2023 Feb 2. doi: 10.1038/s41380-023-01969.
    PubMed     Abstract available


    January 2023
  78. MCCUTCHEON RA, Keefe RSE, McGuire PK
    Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment.
    Mol Psychiatry. 2023 Jan 23. doi: 10.1038/s41380-023-01949.
    PubMed     Abstract available


  79. ENRICO P, Delvecchio G, Turtulici N, Aronica R, et al
    A machine learning approach on whole blood immunomarkers to identify an inflammation-associated psychosis onset subgroup.
    Mol Psychiatry. 2023 Jan 6. doi: 10.1038/s41380-022-01911.
    PubMed     Abstract available


  80. FRISTON K
    Computational psychiatry: from synapses to sentience.
    Mol Psychiatry. 2023;28:256-268.
    PubMed     Abstract available


    December 2022
  81. BARTH C, Kelly S, Nerland S, Jahanshad N, et al
    In vivo white matter microstructure in adolescents with early-onset psychosis: a multi-site mega-analysis.
    Mol Psychiatry. 2022 Dec 12. doi: 10.1038/s41380-022-01901.
    PubMed     Abstract available


  82. CONSTANTINIDES C, Han LKM, Alloza C, Antonucci LA, et al
    Brain ageing in schizophrenia: evidence from 26 international cohorts via the ENIGMA Schizophrenia consortium.
    Mol Psychiatry. 2022 Dec 9. doi: 10.1038/s41380-022-01897.
    PubMed     Abstract available


    November 2022
  83. COLLINS MA, Ji JL, Chung Y, Lympus CA, et al
    Accelerated cortical thinning precedes and predicts conversion to psychosis: The NAPLS3 longitudinal study of youth at clinical high-risk.
    Mol Psychiatry. 2022 Nov 25. doi: 10.1038/s41380-022-01870.
    PubMed     Abstract available


  84. TAYLOR J, de Vries YA, van Loo HM, Kendler KS, et al
    Clinical characteristics indexing genetic differences in schizophrenia: a systematic review.
    Mol Psychiatry. 2022 Nov 18. doi: 10.1038/s41380-022-01850.
    PubMed     Abstract available


  85. WEN J, Trost B, Engchuan W, Halvorsen M, et al
    Rare tandem repeat expansions associate with genes involved in synaptic and neuronal signaling functions in schizophrenia.
    Mol Psychiatry. 2022 Nov 16. pii: 10.1038/s41380-022-01857.
    PubMed     Abstract available


  86. ENE HM, Karry R, Farfara D, Ben-Shachar D, et al
    Mitochondria play an essential role in the trajectory of adolescent neurodevelopment and behavior in adulthood: evidence from a schizophrenia rat model.
    Mol Psychiatry. 2022 Nov 15. pii: 10.1038/s41380-022-01865.
    PubMed     Abstract available


  87. GOO BS, Mun DJ, Kim S, Nhung TTM, et al
    Schizophrenia-associated Mitotic Arrest Deficient-1 (MAD1) regulates the polarity of migrating neurons in the developing neocortex.
    Mol Psychiatry. 2022 Nov 10. pii: 10.1038/s41380-022-01856.
    PubMed     Abstract available


  88. YEO IJ, Yun J, Son DJ, Han SB, et al
    Overexpression of transmembrane TNFalpha in brain endothelial cells induces schizophrenia-relevant behaviors.
    Mol Psychiatry. 2022 Nov 4. pii: 10.1038/s41380-022-01846.
    PubMed     Abstract available


    October 2022
  89. WOLF G, Singh S, Blakolmer K, Lerer L, et al
    Could psychedelic drugs have a role in the treatment of schizophrenia? Rationale and strategy for safe implementation.
    Mol Psychiatry. 2022 Oct 24. pii: 10.1038/s41380-022-01832.
    PubMed     Abstract available


  90. TRINDADE P, Nascimento JM, Casas BS, Monteverde T, et al
    Induced pluripotent stem cell-derived astrocytes from patients with schizophrenia exhibit an inflammatory phenotype that affects vascularization.
    Mol Psychiatry. 2022 Oct 24. pii: 10.1038/s41380-022-01830.
    PubMed     Abstract available


  91. MERIKANGAS AK, Almasy L
    Reply to "Comment on: What genes are differentially expressed in individuals with schizophrenia? A systematic review".
    Mol Psychiatry. 2022 Oct 12. pii: 10.1038/s41380-022-01821.
    PubMed    


  92. BOYER L, Fond G, Pauly V, Orleans V, et al
    Impact of the COVID-19 pandemic on non-COVID-19 hospital mortality in patients with schizophrenia: a nationwide population-based cohort study.
    Mol Psychiatry. 2022 Oct 7. pii: 10.1038/s41380-022-01803.
    PubMed     Abstract available


  93. PUVOGEL S, Alsema A, Kracht L, Webster MJ, et al
    Single-nucleus RNA sequencing of midbrain blood-brain barrier cells in schizophrenia reveals subtle transcriptional changes with overall preservation of cellular proportions and phenotypes.
    Mol Psychiatry. 2022 Oct 3. pii: 10.1038/s41380-022-01796.
    PubMed     Abstract available


  94. FIKSINSKI AM, Hoftman GD, Vorstman JAS, Bearden CE, et al
    A genetics-first approach to understanding autism and schizophrenia spectrum disorders: the 22q11.2 deletion syndrome.
    Mol Psychiatry. 2022 Oct 3. pii: 10.1038/s41380-022-01783.
    PubMed     Abstract available


    September 2022
  95. LENNOX B, Xiong W, Waters P, Coles A, et al
    The serum metabolomic profile of a distinct, inflammatory subtype of acute psychosis.
    Mol Psychiatry. 2022 Sep 21. pii: 10.1038/s41380-022-01784.
    PubMed     Abstract available


  96. PISTIS G, Vazquez-Bourgon J, Fournier M, Jenni R, et al
    Gene set enrichment analysis of pathophysiological pathways highlights oxidative stress in psychosis.
    Mol Psychiatry. 2022 Sep 21. pii: 10.1038/s41380-022-01779.
    PubMed     Abstract available


  97. YU G, Su Y, Guo C, Yi C, et al
    Pathological oligodendrocyte precursor cells revealed in human schizophrenic brains and trigger schizophrenia-like behaviors and synaptic defects in genetic animal model.
    Mol Psychiatry. 2022 Sep 21. pii: 10.1038/s41380-022-01777.
    PubMed     Abstract available


  98. HOFFMAN GE, Jaffe AE, Gandal MJ, Collado-Torres L, et al
    Comment on: What genes are differentially expressed in individuals with schizophrenia? A systematic review.
    Mol Psychiatry. 2022 Sep 19. pii: 10.1038/s41380-022-01781.
    PubMed    


  99. ALVER M, Lykoskoufis N, Ramisch A, Dermitzakis ET, et al
    Leveraging interindividual variability of regulatory activity for refining genetic regulation of gene expression in schizophrenia.
    Mol Psychiatry. 2022 Sep 16. pii: 10.1038/s41380-022-01768.
    PubMed     Abstract available


  100. CHENG W, van der Meer D, Parker N, Hindley G, et al
    Shared genetic architecture between schizophrenia and subcortical brain volumes implicates early neurodevelopmental processes and brain development in childhood.
    Mol Psychiatry. 2022 Sep 13. pii: 10.1038/s41380-022-01751.
    PubMed     Abstract available


    August 2022
  101. SOLMI M, Croatto G, Piva G, Rosson S, et al
    Efficacy and acceptability of psychosocial interventions in schizophrenia: systematic overview and quality appraisal of the meta-analytic evidence.
    Mol Psychiatry. 2022 Aug 23. pii: 10.1038/s41380-022-01727.
    PubMed     Abstract available


  102. SEITZ-HOLLAND J, Wojcik JD, Cetin-Karayumak S, Lyall AE, et al
    Cognitive deficits, clinical variables, and white matter microstructure in schizophrenia: a multisite harmonization study.
    Mol Psychiatry. 2022 Aug 18. pii: 10.1038/s41380-022-01731.
    PubMed     Abstract available


  103. ZOGHBI AW, Lieberman JA, Girgis RR
    The neurobiology of duration of untreated psychosis: a comprehensive review.
    Mol Psychiatry. 2022 Aug 5. pii: 10.1038/s41380-022-01718.
    PubMed     Abstract available


  104. SAPIENZA J, Bosia M, Spangaro M, Martini F, et al
    Schizophrenia and psychedelic state: Dysconnection versus hyper-connection. A perspective on two different models of psychosis stemming from dysfunctional integration processes.
    Mol Psychiatry. 2022 Aug 5. pii: 10.1038/s41380-022-01721.
    PubMed     Abstract available


    July 2022
  105. MCWHINNEY SR, Brosch K, Calhoun VD, Crespo-Facorro B, et al
    Correction: Obesity and brain structure in schizophrenia - ENIGMA study in 3021 individuals.
    Mol Psychiatry. 2022 Jul 20. pii: 10.1038/s41380-022-01696.
    PubMed    


  106. BROSCH K, Stein F, Schmitt S, Pfarr JK, et al
    Reduced hippocampal gray matter volume is a common feature of patients with major depression, bipolar disorder, and schizophrenia spectrum disorders.
    Mol Psychiatry. 2022 Jul 15. pii: 10.1038/s41380-022-01687.
    PubMed     Abstract available


  107. MASTROGIACOMO R, Trigilio G, Devroye C, Dautan D, et al
    Dysbindin-1A modulation of astrocytic dopamine and basal ganglia dependent behaviors relevant to schizophrenia.
    Mol Psychiatry. 2022 Jul 11. pii: 10.1038/s41380-022-01683.
    PubMed     Abstract available


  108. ETCHECOPAR-ETCHART D, Mignon R, Boyer L, Fond G, et al
    Schizophrenia pregnancies should be given greater health priority in the global health agenda: results from a large-scale meta-analysis of 43,611 deliveries of women with schizophrenia and 40,948,272 controls.
    Mol Psychiatry. 2022 Jul 8. pii: 10.1038/s41380-022-01593.
    PubMed     Abstract available


  109. CHIEN YL, Lin HY, Tung YH, Hwang TJ, et al
    Neurodevelopmental model of schizophrenia revisited: similarity in individual deviation and idiosyncrasy from the normative model of whole-brain white matter tracts and shared brain-cognition covariation with ADHD and ASD.
    Mol Psychiatry. 2022 Jul 6. pii: 10.1038/s41380-022-01636.
    PubMed     Abstract available


    June 2022
  110. ALVER M, Mancini V, Lall K, Schneider M, et al
    Contribution of schizophrenia polygenic burden to longitudinal phenotypic variance in 22q11.2 deletion syndrome.
    Mol Psychiatry. 2022 Jun 29. pii: 10.1038/s41380-022-01674.
    PubMed     Abstract available


  111. NI T, Zhu L, Wang S, Zhu W, et al
    Medial prefrontal cortex Notch1 signalling mediates methamphetamine-induced psychosis via Hes1-dependent suppression of GABAB1 receptor expression.
    Mol Psychiatry. 2022 Jun 22. pii: 10.1038/s41380-022-01662.
    PubMed     Abstract available


  112. CASAS BS, Vitoria G, Prieto CP, Casas M, et al
    Schizophrenia-derived hiPSC brain microvascular endothelial-like cells show impairments in angiogenesis and blood-brain barrier function.
    Mol Psychiatry. 2022 Jun 15. pii: 10.1038/s41380-022-01653.
    PubMed     Abstract available


  113. LIU D, Zinski A, Mishra A, Noh H, et al
    Impact of schizophrenia GWAS loci converge onto distinct pathways in cortical interneurons vs glutamatergic neurons during development.
    Mol Psychiatry. 2022 Jun 14. pii: 10.1038/s41380-022-01654.
    PubMed     Abstract available


  114. MCWHINNEY SR, Brosch K, Calhoun VD, Crespo-Facorro B, et al
    Obesity and brain structure in schizophrenia - ENIGMA study in 3021 individuals.
    Mol Psychiatry. 2022 Jun 14. pii: 10.1038/s41380-022-01616.
    PubMed     Abstract available


  115. BUCK SA, Quincy Erickson-Oberg M, Logan RW, Freyberg Z, et al
    Relevance of interactions between dopamine and glutamate neurotransmission in schizophrenia.
    Mol Psychiatry. 2022 Jun 10. pii: 10.1038/s41380-022-01649.
    PubMed     Abstract available


  116. AKINGBUWA WA, Hammerschlag AR, Bartels M, Nivard MG, et al
    Ultra-rare and common genetic variant analysis converge to implicate negative selection and neuronal processes in the aetiology of schizophrenia.
    Mol Psychiatry. 2022 Jun 3. pii: 10.1038/s41380-022-01621.
    PubMed     Abstract available


  117. OLIVER D, Arribas M, Radua J, Salazar de Pablo G, et al
    Prognostic accuracy and clinical utility of psychometric instruments for individuals at clinical high-risk of psychosis: a systematic review and meta-analysis.
    Mol Psychiatry. 2022 Jun 3. pii: 10.1038/s41380-022-01611.
    PubMed     Abstract available


  118. HYDE J, Carr H, Kelley N, Seneviratne R, et al
    Efficacy of neurostimulation across mental disorders: systematic review and meta-analysis of 208 randomized controlled trials.
    Mol Psychiatry. 2022;27:2709-2719.
    PubMed     Abstract available


    May 2022
  119. KOMATSU H, Onoguchi G, Jerotic S, Kanahara N, et al
    Correction: Retinal layers and associated clinical factors in schizophrenia spectrum disorders: a systematic review and meta-analysis.
    Mol Psychiatry. 2022 May 27. pii: 10.1038/s41380-022-01620.
    PubMed    


  120. MATLIK K, Garton DR, Montano-Rodriguez AR, Olfat S, et al
    Elevated endogenous GDNF induces altered dopamine signalling in mice and correlates with clinical severity in schizophrenia.
    Mol Psychiatry. 2022 May 26. pii: 10.1038/s41380-022-01554.
    PubMed     Abstract available


  121. MOJARAD BA, Engchuan W, Trost B, Backstrom I, et al
    Genome-wide tandem repeat expansions contribute to schizophrenia risk.
    Mol Psychiatry. 2022 May 12. pii: 10.1038/s41380-022-01575.
    PubMed     Abstract available


  122. FASS DM, Lewis MC, Ahmad R, Szucs MJ, et al
    Brain-specific deletion of GIT1 impairs cognition and alters phosphorylation of synaptic protein networks implicated in schizophrenia susceptibility.
    Mol Psychiatry. 2022 May 3. pii: 10.1038/s41380-022-01557.
    PubMed     Abstract available


  123. SAARINEN A, Lyytikainen LP, Hietala J, Dobewall H, et al
    Magical thinking in individuals with high polygenic risk for schizophrenia but no non-affective psychoses-a general population study.
    Mol Psychiatry. 2022 May 3. pii: 10.1038/s41380-022-01581.
    PubMed     Abstract available


  124. KOMATSU H, Onoguchi G, Jerotic S, Kanahara N, et al
    Retinal layers and associated clinical factors in schizophrenia spectrum disorders: a systematic review and meta-analysis.
    Mol Psychiatry. 2022 May 2. pii: 10.1038/s41380-022-01591.
    PubMed     Abstract available


    April 2022
  125. CUENOD M, Steullet P, Cabungcal JH, Dwir D, et al
    Caught in vicious circles: a perspective on dynamic feed-forward loops driving oxidative stress in schizophrenia; Response to "Adaptive changes to oxidative stress in schizophrenia by Lena Palaniyappan".
    Mol Psychiatry. 2022 Apr 28. pii: 10.1038/s41380-022-01553.
    PubMed    


  126. WADA M, Noda Y, Iwata Y, Tsugawa S, et al
    Dopaminergic dysfunction and excitatory/inhibitory imbalance in treatment-resistant schizophrenia and novel neuromodulatory treatment.
    Mol Psychiatry. 2022 Apr 20. pii: 10.1038/s41380-022-01572.
    PubMed     Abstract available


  127. ABU-AKEL A, Wood SJ, Upthegrove R, Chisholm K, et al
    Psychosocial functioning in the balance between autism and psychosis: evidence from three populations.
    Mol Psychiatry. 2022 Apr 14. pii: 10.1038/s41380-022-01543.
    PubMed     Abstract available


  128. ABRAM SV, Roach BJ, Fryer SL, Calhoun VD, et al
    Validation of ketamine as a pharmacological model of thalamic dysconnectivity across the illness course of schizophrenia.
    Mol Psychiatry. 2022 Apr 14. pii: 10.1038/s41380-022-01502.
    PubMed     Abstract available


  129. ALMULLA AF, Vasupanrajit A, Tunvirachaisakul C, Al-Hakeim HK, et al
    The tryptophan catabolite or kynurenine pathway in schizophrenia: meta-analysis reveals dissociations between central, serum, and plasma compartments.
    Mol Psychiatry. 2022 Apr 14. pii: 10.1038/s41380-022-01552.
    PubMed     Abstract available


  130. PALANIYAPPAN L
    Adaptive changes to oxidative stress in schizophrenia.
    Mol Psychiatry. 2022 Apr 8. pii: 10.1038/s41380-022-01550.
    PubMed    


  131. AYORA M, Fraguas D, Abregu-Crespo R, Recio S, et al
    Leukocyte telomere length in patients with schizophrenia and related disorders: a meta-analysis of case-control studies.
    Mol Psychiatry. 2022 Apr 7. pii: 10.1038/s41380-022-01541.
    PubMed     Abstract available


  132. SONG J, Yao S, Kowalec K, Lu Y, et al
    The impact of educational attainment, intelligence and intellectual disability on schizophrenia: a Swedish population-based register and genetic study.
    Mol Psychiatry. 2022 Apr 5. pii: 10.1038/s41380-022-01500.
    PubMed     Abstract available


  133. BELLON A, Feuillet V, Cortez-Resendiz A, Mouaffak F, et al
    Dopamine-induced pruning in monocyte-derived-neuronal-like cells (MDNCs) from patients with schizophrenia.
    Mol Psychiatry. 2022 Apr 1. pii: 10.1038/s41380-022-01514.
    PubMed     Abstract available


  134. REN D, Wei X, Lin L, Yuan F, et al
    A novel heterozygous missense variant of the ARID4A gene identified in Han Chinese families with schizophrenia-diagnosed siblings that interferes with DNA-binding activity.
    Mol Psychiatry. 2022 Apr 1. pii: 10.1038/s41380-022-01530.
    PubMed     Abstract available


  135. PERZEL MANDELL KA, Eagles NJ, Deep-Soboslay A, Tao R, et al
    Molecular phenotypes associated with antipsychotic drugs in the human caudate nucleus.
    Mol Psychiatry. 2022;27:2061-2067.
    PubMed     Abstract available


    March 2022
  136. HENKEL ND, Wu X, O'Donovan SM, Devine EA, et al
    Schizophrenia: a disorder of broken brain bioenergetics.
    Mol Psychiatry. 2022 Mar 9. pii: 10.1038/s41380-022-01494.
    PubMed     Abstract available


  137. MEALER RG, Williams SE, Noel M, Yang B, et al
    The schizophrenia-associated variant in SLC39A8 alters protein glycosylation in the mouse brain.
    Mol Psychiatry. 2022 Mar 8. pii: 10.1038/s41380-022-01490.
    PubMed     Abstract available


    February 2022
  138. MCGUINNESS AJ, Davis JA, Dawson SL, Loughman A, et al
    A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophrenia.
    Mol Psychiatry. 2022 Feb 22. pii: 10.1038/s41380-022-01456.
    PubMed     Abstract available


  139. HWANG I, Kim BS, Ko HR, Cho S, et al
    Cerebellar dysfunction and schizophrenia-like behavior in Ebp1-deficient mice.
    Mol Psychiatry. 2022 Feb 15. pii: 10.1038/s41380-022-01458.
    PubMed     Abstract available


  140. DI BIASE MA, Geaghan MP, Reay WR, Seidlitz J, et al
    Cell type-specific manifestations of cortical thickness heterogeneity in schizophrenia.
    Mol Psychiatry. 2022 Feb 10. pii: 10.1038/s41380-022-01460.
    PubMed     Abstract available


  141. OLISLAGERS M, Rademaker K, Adan RAH, Lin BD, et al
    Comprehensive analyses of RNA-seq and genome-wide data point to enrichment of neuronal cell type subsets in neuropsychiatric disorders.
    Mol Psychiatry. 2022;27:947-955.
    PubMed     Abstract available


  142. KIRSCHNER M, Hodzic-Santor B, Antoniades M, Nenadic I, et al
    Cortical and subcortical neuroanatomical signatures of schizotypy in 3004 individuals assessed in a worldwide ENIGMA study.
    Mol Psychiatry. 2022;27:1167-1176.
    PubMed     Abstract available


    January 2022
  143. MERIKANGAS AK, Shelly M, Knighton A, Kotler N, et al
    What genes are differentially expressed in individuals with schizophrenia? A systematic review.
    Mol Psychiatry. 2022 Jan 28. pii: 10.1038/s41380-021-01420.
    PubMed     Abstract available


  144. EL KHOUEIRY C, Cabungcal JH, Rovo Z, Fournier M, et al
    Developmental oxidative stress leads to T-type Ca(2+) channel hypofunction in thalamic reticular nucleus of mouse models pertinent to schizophrenia.
    Mol Psychiatry. 2022 Jan 25. pii: 10.1038/s41380-021-01425.
    PubMed     Abstract available


  145. LI W, Lv L, Luo XJ
    In vivo study sheds new light on the dendritic spine pathology hypothesis of schizophrenia.
    Mol Psychiatry. 2022 Jan 25. pii: 10.1038/s41380-022-01449.
    PubMed    


  146. SIMPSON EH, Gallo EF, Balsam PD, Javitch JA, et al
    How changes in dopamine D2 receptor levels alter striatal circuit function and motivation.
    Mol Psychiatry. 2022;27:436-444.
    PubMed     Abstract available


  147. NAIR PC, Miners JO, McKinnon RA, Langmead CJ, et al
    Binding of SEP-363856 within TAAR1 and the 5HT1A receptor: implications for the design of novel antipsychotic drugs.
    Mol Psychiatry. 2022;27:88-94.
    PubMed     Abstract available


    December 2021
  148. ERADY C, Amin K, Onilogbo TOAE, Tomasik J, et al
    Novel open reading frames in human accelerated regions and transposable elements reveal new leads to understand schizophrenia and bipolar disorder.
    Mol Psychiatry. 2021 Dec 23. pii: 10.1038/s41380-021-01405.
    PubMed     Abstract available


  149. HASSAN L, Peek N, Lovell K, Carvalho AF, et al
    Disparities in COVID-19 infection, hospitalisation and death in people with schizophrenia, bipolar disorder, and major depressive disorder: a cohort study of the UK Biobank.
    Mol Psychiatry. 2021 Dec 7. pii: 10.1038/s41380-021-01344.
    PubMed     Abstract available


  150. BAGAUTDINOVA J, Zoller D, Schaer M, Padula MC, et al
    Altered cortical thickness development in 22q11.2 deletion syndrome and association with psychotic symptoms.
    Mol Psychiatry. 2021;26:7671-7678.
    PubMed     Abstract available


    November 2021
  151. ALKELAI A, Greenbaum L, Docherty AR, Shabalin AA, et al
    The benefit of diagnostic whole genome sequencing in schizophrenia and other psychotic disorders.
    Mol Psychiatry. 2021 Nov 19. pii: 10.1038/s41380-021-01383.
    PubMed     Abstract available


  152. ZHANG R, Sjolander A, Ploner A, Lu D, et al
    Novel disease associations with schizophrenia genetic risk revealed in ~400,000 UK Biobank participants.
    Mol Psychiatry. 2021 Nov 19. pii: 10.1038/s41380-021-01387.
    PubMed     Abstract available


  153. NOTARAS M, Lodhi A, Dundar F, Collier P, et al
    Schizophrenia is defined by cell-specific neuropathology and multiple neurodevelopmental mechanisms in patient-derived cerebral organoids.
    Mol Psychiatry. 2021 Nov 17. pii: 10.1038/s41380-021-01316.
    PubMed     Abstract available


  154. EISENBERG DP, Kohn PD, Hegarty CE, Smith NR, et al
    Clinical correlation but no elevation of striatal dopamine synthesis capacity in two independent cohorts of medication-free individuals with schizophrenia.
    Mol Psychiatry. 2021 Nov 17. pii: 10.1038/s41380-021-01337.
    PubMed     Abstract available


  155. PLAVEN-SIGRAY P, Ikonen Victorsson P, Santillo A, Matheson GJ, et al
    Thalamic dopamine D2-receptor availability in schizophrenia: a study on antipsychotic-naive patients with first-episode psychosis and a meta-analysis.
    Mol Psychiatry. 2021 Nov 10. pii: 10.1038/s41380-021-01349.
    PubMed     Abstract available


  156. CUENOD M, Steullet P, Cabungcal JH, Dwir D, et al
    Caught in vicious circles: a perspective on dynamic feed-forward loops driving oxidative stress in schizophrenia.
    Mol Psychiatry. 2021 Nov 10. pii: 10.1038/s41380-021-01374.
    PubMed     Abstract available


  157. ZHOU X
    Over-representation of potential SP4 target genes within schizophrenia-risk genes.
    Mol Psychiatry. 2021 Nov 8. pii: 10.1038/s41380-021-01376.
    PubMed     Abstract available


  158. SELLGREN CM, Imbeault S, Larsson MK, Oliveros A, et al
    Correction: GRK3 deficiency elicits brain immune activation and psychosis.
    Mol Psychiatry. 2021 Nov 8. pii: 10.1038/s41380-021-01371.
    PubMed    


  159. CAMPEAU A, Mills RH, Stevens T, Rossitto LA, et al
    Multi-omics of human plasma reveals molecular features of dysregulated inflammation and accelerated aging in schizophrenia.
    Mol Psychiatry. 2021 Nov 5. pii: 10.1038/s41380-021-01339.
    PubMed     Abstract available


  160. GAO Y, Fan Y, Yang Z, Ma Q, et al
    Systems biological assessment of altered cytokine responses to bacteria and fungi reveals impaired immune functionality in schizophrenia.
    Mol Psychiatry. 2021 Nov 2. pii: 10.1038/s41380-021-01362.
    PubMed     Abstract available


  161. LI Q, Wang Z, Zong L, Ye L, et al
    Allele-specific DNA methylation maps in monozygotic twins discordant for psychiatric disorders reveal that disease-associated switching at the EIPR1 regulatory loci modulates neural function.
    Mol Psychiatry. 2021;26:6630-6642.
    PubMed     Abstract available


    October 2021
  162. CHAN SY, Brady RO, Lewandowski KE, Higgins A, et al
    Dynamic and progressive changes in thalamic functional connectivity over the first five years of psychosis.
    Mol Psychiatry. 2021 Oct 25. pii: 10.1038/s41380-021-01319.
    PubMed     Abstract available


  163. KHADIMALLAH I, Jenni R, Cabungcal JH, Cleusix M, et al
    Mitochondrial, exosomal miR137-COX6A2 and gamma synchrony as biomarkers of parvalbumin interneurons, psychopathology, and neurocognition in schizophrenia.
    Mol Psychiatry. 2021 Oct 22. pii: 10.1038/s41380-021-01313.
    PubMed     Abstract available


  164. WOLF DH, Zheng D, Kohler C, Turetsky BI, et al
    Effect of mGluR2 positive allosteric modulation on frontostriatal working memory activation in schizophrenia.
    Mol Psychiatry. 2021 Oct 20. pii: 10.1038/s41380-021-01320.
    PubMed     Abstract available


  165. YANG K, Longo L, Narita Z, Cascella N, et al
    A multimodal study of a first episode psychosis cohort: potential markers of antipsychotic treatment resistance.
    Mol Psychiatry. 2021 Oct 12. pii: 10.1038/s41380-021-01331.
    PubMed     Abstract available


    September 2021
  166. LUO C, Pi X, Hu N, Wang X, et al
    Subtypes of schizophrenia identified by multi-omic measures associated with dysregulated immune function.
    Mol Psychiatry. 2021 Sep 29. pii: 10.1038/s41380-021-01308.
    PubMed     Abstract available


  167. NAKAHARA T, Tsugawa S, Noda Y, Ueno F, et al
    Glutamatergic and GABAergic metabolite levels in schizophrenia-spectrum disorders: a meta-analysis of (1)H-magnetic resonance spectroscopy studies.
    Mol Psychiatry. 2021 Sep 28. pii: 10.1038/s41380-021-01297.
    PubMed     Abstract available


  168. SAARENTAUS EC, Havulinna AS, Mars N, Ahola-Olli A, et al
    Polygenic burden has broader impact on health, cognition, and socioeconomic outcomes than most rare and high-risk copy number variants.
    Mol Psychiatry. 2021;26:4884-4895.
    PubMed     Abstract available


  169. JIA X, Goes FS, Locke AE, Palmer D, et al
    Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder.
    Mol Psychiatry. 2021;26:5239-5250.
    PubMed     Abstract available


    August 2021
  170. STAUFFER EM, Bethlehem RAI, Warrier V, Murray GK, et al
    Grey and white matter microstructure is associated with polygenic risk for schizophrenia.
    Mol Psychiatry. 2021 Aug 30. pii: 10.1038/s41380-021-01260.
    PubMed     Abstract available


  171. LI Y, Li S, Liu J, Huo Y, et al
    The schizophrenia susceptibility gene NAGA regulates dendritic spine density: further evidence for the dendritic spine pathology of schizophrenia.
    Mol Psychiatry. 2021 Aug 10. pii: 10.1038/s41380-021-01261.
    PubMed    


  172. RAUBER S, Heming M, Repple J, Ruland T, et al
    Cerebrospinal fluid flow cytometry distinguishes psychosis spectrum disorders from differential diagnoses.
    Mol Psychiatry. 2021 Aug 6. pii: 10.1038/s41380-021-01244.
    PubMed     Abstract available


  173. TAKAYANAGI Y, Ishizuka K, Laursen TM, Yukitake H, et al
    From population to neuron: exploring common mediators for metabolic problems and mental illnesses.
    Mol Psychiatry. 2021;26:3931-3942.
    PubMed     Abstract available


  174. NI C, Jiang W, Wang Z, Wang Z, et al
    LncRNA-AC006129.1 reactivates a SOCS3-mediated anti-inflammatory response through DNA methylation-mediated CIC downregulation in schizophrenia.
    Mol Psychiatry. 2021;26:4511-4528.
    PubMed     Abstract available


  175. CLEYNEN I, Engchuan W, Hestand MS, Heung T, et al
    Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion.
    Mol Psychiatry. 2021;26:4496-4510.
    PubMed     Abstract available


  176. GOBSHTIS N, Tfilin M, Fraifeld VE, Turgeman G, et al
    Transplantation of mesenchymal stem cells causes long-term alleviation of schizophrenia-like behaviour coupled with increased neurogenesis.
    Mol Psychiatry. 2021;26:4448-4463.
    PubMed     Abstract available


  177. GREENING DW, Notaras M, Chen M, Xu R, et al
    Chronic methamphetamine interacts with BDNF Val66Met to remodel psychosis pathways in the mesocorticolimbic proteome.
    Mol Psychiatry. 2021;26:4431-4447.
    PubMed     Abstract available


  178. HARRISON PJ, Hall N, Mould A, Al-Juffali N, et al
    Cellular calcium in bipolar disorder: systematic review and meta-analysis.
    Mol Psychiatry. 2021;26:4106-4116.
    PubMed     Abstract available


  179. BORGAN F, O'Daly O, Veronese M, Reis Marques T, et al
    The neural and molecular basis of working memory function in psychosis: a multimodal PET-fMRI study.
    Mol Psychiatry. 2021;26:4464-4474.
    PubMed     Abstract available


  180. KOWALEC K, Lu Y, Sariaslan A, Song J, et al
    Increased schizophrenia family history burden and reduced premorbid IQ in treatment-resistant schizophrenia: a Swedish National Register and Genomic Study.
    Mol Psychiatry. 2021;26:4487-4495.
    PubMed     Abstract available


    July 2021
  181. LIU Z, Palaniyappan L, Wu X, Zhang K, et al
    Resolving heterogeneity in schizophrenia through a novel systems approach to brain structure: individualized structural covariance network analysis.
    Mol Psychiatry. 2021 Jul 28. pii: 10.1038/s41380-021-01229.
    PubMed     Abstract available


  182. MURPHY CE, Weickert CS
    A new suspect in the unsolved case of neuroinflammation in schizophrenia.
    Mol Psychiatry. 2021 Jul 20. pii: 10.1038/s41380-021-01225.
    PubMed    


  183. WU X, Shukla R, Alganem K, Zhang X, et al
    Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity.
    Mol Psychiatry. 2021 Jul 16. pii: 10.1038/s41380-021-01205.
    PubMed     Abstract available


  184. HEURICH M, Focking M, Mongan D, Cagney G, et al
    Dysregulation of complement and coagulation pathways: emerging mechanisms in the development of psychosis.
    Mol Psychiatry. 2021 Jul 5. pii: 10.1038/s41380-021-01197.
    PubMed     Abstract available


  185. SHA Z, Schijven D, Francks C
    Patterns of brain asymmetry associated with polygenic risks for autism and schizophrenia implicate language and executive functions but not brain masculinization.
    Mol Psychiatry. 2021 Jul 1. pii: 10.1038/s41380-021-01204.
    PubMed     Abstract available


  186. STEIXNER-KUMAR AA, Daguano Gastaldi V, Seidel J, Rosenberger A, et al
    Preadult polytoxicomania-strong environmental underpinnings and first genetic hints.
    Mol Psychiatry. 2021;26:3211-3222.
    PubMed     Abstract available


  187. CLIFTON NE, Rees E, Holmans PA, Pardinas AF, et al
    Genetic association of FMRP targets with psychiatric disorders.
    Mol Psychiatry. 2021;26:2977-2990.
    PubMed     Abstract available


    June 2021
  188. ZHU X, Cabungcal JH, Cuenod M, Uliana DL, et al
    Thalamic reticular nucleus impairments and abnormal prefrontal control of dopamine system in a developmental model of schizophrenia: prevention by N-acetylcysteine.
    Mol Psychiatry. 2021 Jun 30. pii: 10.1038/s41380-021-01198.
    PubMed     Abstract available


  189. GUAN F, Ni T, Zhu W, Williams LK, et al
    Integrative omics of schizophrenia: from genetic determinants to clinical classification and risk prediction.
    Mol Psychiatry. 2021 Jun 30. pii: 10.1038/s41380-021-01201.
    PubMed     Abstract available


  190. GAO WJ, Yang SS, Mack NR, Chamberlin LA, et al
    Aberrant maturation and connectivity of prefrontal cortex in schizophrenia-contribution of NMDA receptor development and hypofunction.
    Mol Psychiatry. 2021 Jun 23. pii: 10.1038/s41380-021-01196.
    PubMed     Abstract available


  191. ROGDAKI M, Devroye C, Ciampoli M, Veronese M, et al
    Correction: Striatal dopaminergic alterations in individuals with copy number variants at the 22q11.2 genetic locus and their implications for psychosis risk: a [18F]-DOPA PET study.
    Mol Psychiatry. 2021 Jun 22. pii: 10.1038/s41380-021-01192.
    PubMed    


  192. RADHAKRISHNAN R, Skosnik PD, Ranganathan M, Naganawa M, et al
    In vivo evidence of lower synaptic vesicle density in schizophrenia.
    Mol Psychiatry. 2021 Jun 16. pii: 10.1038/s41380-021-01184.
    PubMed     Abstract available


  193. DEMICHELE-SWEET MAA, Klei L, Creese B, Harwood JC, et al
    Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease.
    Mol Psychiatry. 2021 Jun 10. pii: 10.1038/s41380-021-01152.
    PubMed     Abstract available


  194. TIGARET CM, Lin TE, Morrell ER, Sykes L, et al
    Neurotrophin receptor activation rescues cognitive and synaptic abnormalities caused by hemizygosity of the psychiatric risk gene Cacna1c.
    Mol Psychiatry. 2021;26:1748-1760.
    PubMed     Abstract available


  195. BYRNE EM, Zhu Z, Qi T, Skene NG, et al
    Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders.
    Mol Psychiatry. 2021;26:2070-2081.
    PubMed     Abstract available


  196. PEREZ JM, Berto S, Gleason K, Ghose S, et al
    Hippocampal subfield transcriptome analysis in schizophrenia psychosis.
    Mol Psychiatry. 2021;26:2577-2589.
    PubMed     Abstract available


  197. CAO H, Zhou H, Cannon TD
    Functional connectome-wide associations of schizophrenia polygenic risk.
    Mol Psychiatry. 2021;26:2553-2561.
    PubMed     Abstract available


  198. MA L, Shcherbina A, Chetty S
    Variations and expression features of CYP2D6 contribute to schizophrenia risk.
    Mol Psychiatry. 2021;26:2605-2615.
    PubMed     Abstract available


    May 2021
  199. WEISSLEDER C, North HF, Bitar M, Fullerton JM, et al
    Reduced adult neurogenesis is associated with increased macrophages in the subependymal zone in schizophrenia.
    Mol Psychiatry. 2021 May 31. pii: 10.1038/s41380-021-01149.
    PubMed     Abstract available


  200. DI BIASE MA, Cetin-Karayumak S, Lyall AE, Zalesky A, et al
    White matter changes in psychosis risk relate to development and are not impacted by the transition to psychosis.
    Mol Psychiatry. 2021 May 24. pii: 10.1038/s41380-021-01128.
    PubMed     Abstract available


  201. CHADHA R, Alganem K, Mccullumsmith RE, Meador-Woodruff JH, et al
    mTOR kinase activity disrupts a phosphorylation signaling network in schizophrenia brain.
    Mol Psychiatry. 2021 May 14. pii: 10.1038/s41380-021-01135.
    PubMed     Abstract available


  202. KARIMI B, Silwal P, Booth S, Padmanabhan N, et al
    Schizophrenia-associated LRRTM1 regulates cognitive behavior through controlling synaptic function in the mediodorsal thalamus.
    Mol Psychiatry. 2021 May 12. pii: 10.1038/s41380-021-01146.
    PubMed     Abstract available


  203. ROGDAKI M, Devroye C, Ciampoli M, Veronese M, et al
    Striatal dopaminergic alterations in individuals with copy number variants at the 22q11.2 genetic locus and their implications for psychosis risk: a [18F]-DOPA PET study.
    Mol Psychiatry. 2021 May 12. pii: 10.1038/s41380-021-01108.
    PubMed     Abstract available


  204. SELLGREN CM, Imbeault S, Larsson MK, Oliveros A, et al
    GRK3 deficiency elicits brain immune activation and psychosis.
    Mol Psychiatry. 2021 May 12. pii: 10.1038/s41380-021-01106.
    PubMed     Abstract available


    April 2021
  205. LI Y, Ma C, Li W, Yang Y, et al
    A missense variant in NDUFA6 confers schizophrenia risk by affecting YY1 binding and NAGA expression.
    Mol Psychiatry. 2021 Apr 30. pii: 10.1038/s41380-021-01125.
    PubMed     Abstract available


  206. SHEN M, Guo Y, Dong Q, Gao Y, et al
    FXR1 regulation of parvalbumin interneurons in the prefrontal cortex is critical for schizophrenia-like behaviors.
    Mol Psychiatry. 2021 Apr 16. pii: 10.1038/s41380-021-01096.
    PubMed     Abstract available


  207. DRUART M, Nosten-Bertrand M, Poll S, Crux S, et al
    Elevated expression of complement C4 in the mouse prefrontal cortex causes schizophrenia-associated phenotypes.
    Mol Psychiatry. 2021 Apr 9. pii: 10.1038/s41380-021-01081.
    PubMed     Abstract available


  208. ANDLAUER TFM, Guzman-Parra J, Streit F, Strohmaier J, et al
    Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders.
    Mol Psychiatry. 2021;26:1286-1298.
    PubMed     Abstract available


  209. LEGGIO GM, Torrisi SA, Mastrogiacomo R, Mauro D, et al
    The epistatic interaction between the dopamine D3 receptor and dysbindin-1 modulates higher-order cognitive functions in mice and humans.
    Mol Psychiatry. 2021;26:1272-1285.
    PubMed     Abstract available


    March 2021
  210. SINHA V, Ukkola-Vuoti L, Ortega-Alonso A, Torniainen-Holm M, et al
    Variants in regulatory elements of PDE4D associate with major mental illness in the Finnish population.
    Mol Psychiatry. 2021;26:816-824.
    PubMed     Abstract available


    February 2021
  211. RATHJE M, Waxman H, Benoit M, Tammineni P, et al
    Genetic variants in the bipolar disorder risk locus SYNE1 that affect CPG2 expression and protein function.
    Mol Psychiatry. 2021;26:508-523.
    PubMed     Abstract available


    January 2021
  212. NORTHOFF G, Hirjak D, Wolf RC, Magioncalda P, et al
    All roads lead to the motor cortex: psychomotor mechanisms and their biochemical modulation in psychiatric disorders.
    Mol Psychiatry. 2021;26:92-102.
    PubMed     Abstract available


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