Home The Word Brain My Amedeo FAQ Privacy About Flying Publisher   


The Angels Initiative

Stroke prevention


  Schizophrenia

  Free Subscription


Articles published in Mol Psychiatry

Retrieve available abstracts of 129 articles:
HTML format



Single Articles


    November 2022
  1. TAYLOR J, de Vries YA, van Loo HM, Kendler KS, et al
    Clinical characteristics indexing genetic differences in schizophrenia: a systematic review.
    Mol Psychiatry. 2022 Nov 18. doi: 10.1038/s41380-022-01850.
    PubMed     Abstract available


  2. WEN J, Trost B, Engchuan W, Halvorsen M, et al
    Rare tandem repeat expansions associate with genes involved in synaptic and neuronal signaling functions in schizophrenia.
    Mol Psychiatry. 2022 Nov 16. pii: 10.1038/s41380-022-01857.
    PubMed     Abstract available


  3. ENE HM, Karry R, Farfara D, Ben-Shachar D, et al
    Mitochondria play an essential role in the trajectory of adolescent neurodevelopment and behavior in adulthood: evidence from a schizophrenia rat model.
    Mol Psychiatry. 2022 Nov 15. pii: 10.1038/s41380-022-01865.
    PubMed     Abstract available


  4. GOO BS, Mun DJ, Kim S, Nhung TTM, et al
    Schizophrenia-associated Mitotic Arrest Deficient-1 (MAD1) regulates the polarity of migrating neurons in the developing neocortex.
    Mol Psychiatry. 2022 Nov 10. pii: 10.1038/s41380-022-01856.
    PubMed     Abstract available


  5. YEO IJ, Yun J, Son DJ, Han SB, et al
    Overexpression of transmembrane TNFalpha in brain endothelial cells induces schizophrenia-relevant behaviors.
    Mol Psychiatry. 2022 Nov 4. pii: 10.1038/s41380-022-01846.
    PubMed     Abstract available


    October 2022
  6. WOLF G, Singh S, Blakolmer K, Lerer L, et al
    Could psychedelic drugs have a role in the treatment of schizophrenia? Rationale and strategy for safe implementation.
    Mol Psychiatry. 2022 Oct 24. pii: 10.1038/s41380-022-01832.
    PubMed     Abstract available


  7. TRINDADE P, Nascimento JM, Casas BS, Monteverde T, et al
    Induced pluripotent stem cell-derived astrocytes from patients with schizophrenia exhibit an inflammatory phenotype that affects vascularization.
    Mol Psychiatry. 2022 Oct 24. pii: 10.1038/s41380-022-01830.
    PubMed     Abstract available


  8. MERIKANGAS AK, Almasy L
    Reply to "Comment on: What genes are differentially expressed in individuals with schizophrenia? A systematic review".
    Mol Psychiatry. 2022 Oct 12. pii: 10.1038/s41380-022-01821.
    PubMed    


  9. BOYER L, Fond G, Pauly V, Orleans V, et al
    Impact of the COVID-19 pandemic on non-COVID-19 hospital mortality in patients with schizophrenia: a nationwide population-based cohort study.
    Mol Psychiatry. 2022 Oct 7. pii: 10.1038/s41380-022-01803.
    PubMed     Abstract available


  10. PUVOGEL S, Alsema A, Kracht L, Webster MJ, et al
    Single-nucleus RNA sequencing of midbrain blood-brain barrier cells in schizophrenia reveals subtle transcriptional changes with overall preservation of cellular proportions and phenotypes.
    Mol Psychiatry. 2022 Oct 3. pii: 10.1038/s41380-022-01796.
    PubMed     Abstract available


  11. FIKSINSKI AM, Hoftman GD, Vorstman JAS, Bearden CE, et al
    A genetics-first approach to understanding autism and schizophrenia spectrum disorders: the 22q11.2 deletion syndrome.
    Mol Psychiatry. 2022 Oct 3. pii: 10.1038/s41380-022-01783.
    PubMed     Abstract available


    September 2022
  12. LENNOX B, Xiong W, Waters P, Coles A, et al
    The serum metabolomic profile of a distinct, inflammatory subtype of acute psychosis.
    Mol Psychiatry. 2022 Sep 21. pii: 10.1038/s41380-022-01784.
    PubMed     Abstract available


  13. PISTIS G, Vazquez-Bourgon J, Fournier M, Jenni R, et al
    Gene set enrichment analysis of pathophysiological pathways highlights oxidative stress in psychosis.
    Mol Psychiatry. 2022 Sep 21. pii: 10.1038/s41380-022-01779.
    PubMed     Abstract available


  14. YU G, Su Y, Guo C, Yi C, et al
    Pathological oligodendrocyte precursor cells revealed in human schizophrenic brains and trigger schizophrenia-like behaviors and synaptic defects in genetic animal model.
    Mol Psychiatry. 2022 Sep 21. pii: 10.1038/s41380-022-01777.
    PubMed     Abstract available


  15. HOFFMAN GE, Jaffe AE, Gandal MJ, Collado-Torres L, et al
    Comment on: What genes are differentially expressed in individuals with schizophrenia? A systematic review.
    Mol Psychiatry. 2022 Sep 19. pii: 10.1038/s41380-022-01781.
    PubMed    


  16. ALVER M, Lykoskoufis N, Ramisch A, Dermitzakis ET, et al
    Leveraging interindividual variability of regulatory activity for refining genetic regulation of gene expression in schizophrenia.
    Mol Psychiatry. 2022 Sep 16. pii: 10.1038/s41380-022-01768.
    PubMed     Abstract available


  17. CHENG W, van der Meer D, Parker N, Hindley G, et al
    Shared genetic architecture between schizophrenia and subcortical brain volumes implicates early neurodevelopmental processes and brain development in childhood.
    Mol Psychiatry. 2022 Sep 13. pii: 10.1038/s41380-022-01751.
    PubMed     Abstract available


    August 2022
  18. SOLMI M, Croatto G, Piva G, Rosson S, et al
    Efficacy and acceptability of psychosocial interventions in schizophrenia: systematic overview and quality appraisal of the meta-analytic evidence.
    Mol Psychiatry. 2022 Aug 23. pii: 10.1038/s41380-022-01727.
    PubMed     Abstract available


  19. SEITZ-HOLLAND J, Wojcik JD, Cetin-Karayumak S, Lyall AE, et al
    Cognitive deficits, clinical variables, and white matter microstructure in schizophrenia: a multisite harmonization study.
    Mol Psychiatry. 2022 Aug 18. pii: 10.1038/s41380-022-01731.
    PubMed     Abstract available


  20. ZOGHBI AW, Lieberman JA, Girgis RR
    The neurobiology of duration of untreated psychosis: a comprehensive review.
    Mol Psychiatry. 2022 Aug 5. pii: 10.1038/s41380-022-01718.
    PubMed     Abstract available


  21. SAPIENZA J, Bosia M, Spangaro M, Martini F, et al
    Schizophrenia and psychedelic state: Dysconnection versus hyper-connection. A perspective on two different models of psychosis stemming from dysfunctional integration processes.
    Mol Psychiatry. 2022 Aug 5. pii: 10.1038/s41380-022-01721.
    PubMed     Abstract available


    July 2022
  22. MCWHINNEY SR, Brosch K, Calhoun VD, Crespo-Facorro B, et al
    Correction: Obesity and brain structure in schizophrenia - ENIGMA study in 3021 individuals.
    Mol Psychiatry. 2022 Jul 20. pii: 10.1038/s41380-022-01696.
    PubMed    


  23. BROSCH K, Stein F, Schmitt S, Pfarr JK, et al
    Reduced hippocampal gray matter volume is a common feature of patients with major depression, bipolar disorder, and schizophrenia spectrum disorders.
    Mol Psychiatry. 2022 Jul 15. pii: 10.1038/s41380-022-01687.
    PubMed     Abstract available


  24. MASTROGIACOMO R, Trigilio G, Devroye C, Dautan D, et al
    Dysbindin-1A modulation of astrocytic dopamine and basal ganglia dependent behaviors relevant to schizophrenia.
    Mol Psychiatry. 2022 Jul 11. pii: 10.1038/s41380-022-01683.
    PubMed     Abstract available


  25. ETCHECOPAR-ETCHART D, Mignon R, Boyer L, Fond G, et al
    Schizophrenia pregnancies should be given greater health priority in the global health agenda: results from a large-scale meta-analysis of 43,611 deliveries of women with schizophrenia and 40,948,272 controls.
    Mol Psychiatry. 2022 Jul 8. pii: 10.1038/s41380-022-01593.
    PubMed     Abstract available


  26. CHIEN YL, Lin HY, Tung YH, Hwang TJ, et al
    Neurodevelopmental model of schizophrenia revisited: similarity in individual deviation and idiosyncrasy from the normative model of whole-brain white matter tracts and shared brain-cognition covariation with ADHD and ASD.
    Mol Psychiatry. 2022 Jul 6. pii: 10.1038/s41380-022-01636.
    PubMed     Abstract available


    June 2022
  27. ALVER M, Mancini V, Lall K, Schneider M, et al
    Contribution of schizophrenia polygenic burden to longitudinal phenotypic variance in 22q11.2 deletion syndrome.
    Mol Psychiatry. 2022 Jun 29. pii: 10.1038/s41380-022-01674.
    PubMed     Abstract available


  28. NI T, Zhu L, Wang S, Zhu W, et al
    Medial prefrontal cortex Notch1 signalling mediates methamphetamine-induced psychosis via Hes1-dependent suppression of GABAB1 receptor expression.
    Mol Psychiatry. 2022 Jun 22. pii: 10.1038/s41380-022-01662.
    PubMed     Abstract available


  29. CASAS BS, Vitoria G, Prieto CP, Casas M, et al
    Schizophrenia-derived hiPSC brain microvascular endothelial-like cells show impairments in angiogenesis and blood-brain barrier function.
    Mol Psychiatry. 2022 Jun 15. pii: 10.1038/s41380-022-01653.
    PubMed     Abstract available


  30. LIU D, Zinski A, Mishra A, Noh H, et al
    Impact of schizophrenia GWAS loci converge onto distinct pathways in cortical interneurons vs glutamatergic neurons during development.
    Mol Psychiatry. 2022 Jun 14. pii: 10.1038/s41380-022-01654.
    PubMed     Abstract available


  31. MCWHINNEY SR, Brosch K, Calhoun VD, Crespo-Facorro B, et al
    Obesity and brain structure in schizophrenia - ENIGMA study in 3021 individuals.
    Mol Psychiatry. 2022 Jun 14. pii: 10.1038/s41380-022-01616.
    PubMed     Abstract available


  32. BUCK SA, Quincy Erickson-Oberg M, Logan RW, Freyberg Z, et al
    Relevance of interactions between dopamine and glutamate neurotransmission in schizophrenia.
    Mol Psychiatry. 2022 Jun 10. pii: 10.1038/s41380-022-01649.
    PubMed     Abstract available


  33. AKINGBUWA WA, Hammerschlag AR, Bartels M, Nivard MG, et al
    Ultra-rare and common genetic variant analysis converge to implicate negative selection and neuronal processes in the aetiology of schizophrenia.
    Mol Psychiatry. 2022 Jun 3. pii: 10.1038/s41380-022-01621.
    PubMed     Abstract available


  34. OLIVER D, Arribas M, Radua J, Salazar de Pablo G, et al
    Prognostic accuracy and clinical utility of psychometric instruments for individuals at clinical high-risk of psychosis: a systematic review and meta-analysis.
    Mol Psychiatry. 2022 Jun 3. pii: 10.1038/s41380-022-01611.
    PubMed     Abstract available


  35. HYDE J, Carr H, Kelley N, Seneviratne R, et al
    Efficacy of neurostimulation across mental disorders: systematic review and meta-analysis of 208 randomized controlled trials.
    Mol Psychiatry. 2022;27:2709-2719.
    PubMed     Abstract available


    May 2022
  36. KOMATSU H, Onoguchi G, Jerotic S, Kanahara N, et al
    Correction: Retinal layers and associated clinical factors in schizophrenia spectrum disorders: a systematic review and meta-analysis.
    Mol Psychiatry. 2022 May 27. pii: 10.1038/s41380-022-01620.
    PubMed    


  37. MATLIK K, Garton DR, Montano-Rodriguez AR, Olfat S, et al
    Elevated endogenous GDNF induces altered dopamine signalling in mice and correlates with clinical severity in schizophrenia.
    Mol Psychiatry. 2022 May 26. pii: 10.1038/s41380-022-01554.
    PubMed     Abstract available


  38. MOJARAD BA, Engchuan W, Trost B, Backstrom I, et al
    Genome-wide tandem repeat expansions contribute to schizophrenia risk.
    Mol Psychiatry. 2022 May 12. pii: 10.1038/s41380-022-01575.
    PubMed     Abstract available


  39. FASS DM, Lewis MC, Ahmad R, Szucs MJ, et al
    Brain-specific deletion of GIT1 impairs cognition and alters phosphorylation of synaptic protein networks implicated in schizophrenia susceptibility.
    Mol Psychiatry. 2022 May 3. pii: 10.1038/s41380-022-01557.
    PubMed     Abstract available


  40. SAARINEN A, Lyytikainen LP, Hietala J, Dobewall H, et al
    Magical thinking in individuals with high polygenic risk for schizophrenia but no non-affective psychoses-a general population study.
    Mol Psychiatry. 2022 May 3. pii: 10.1038/s41380-022-01581.
    PubMed     Abstract available


  41. KOMATSU H, Onoguchi G, Jerotic S, Kanahara N, et al
    Retinal layers and associated clinical factors in schizophrenia spectrum disorders: a systematic review and meta-analysis.
    Mol Psychiatry. 2022 May 2. pii: 10.1038/s41380-022-01591.
    PubMed     Abstract available


    April 2022
  42. CUENOD M, Steullet P, Cabungcal JH, Dwir D, et al
    Caught in vicious circles: a perspective on dynamic feed-forward loops driving oxidative stress in schizophrenia; Response to "Adaptive changes to oxidative stress in schizophrenia by Lena Palaniyappan".
    Mol Psychiatry. 2022 Apr 28. pii: 10.1038/s41380-022-01553.
    PubMed    


  43. WADA M, Noda Y, Iwata Y, Tsugawa S, et al
    Dopaminergic dysfunction and excitatory/inhibitory imbalance in treatment-resistant schizophrenia and novel neuromodulatory treatment.
    Mol Psychiatry. 2022 Apr 20. pii: 10.1038/s41380-022-01572.
    PubMed     Abstract available


  44. ABU-AKEL A, Wood SJ, Upthegrove R, Chisholm K, et al
    Psychosocial functioning in the balance between autism and psychosis: evidence from three populations.
    Mol Psychiatry. 2022 Apr 14. pii: 10.1038/s41380-022-01543.
    PubMed     Abstract available


  45. ABRAM SV, Roach BJ, Fryer SL, Calhoun VD, et al
    Validation of ketamine as a pharmacological model of thalamic dysconnectivity across the illness course of schizophrenia.
    Mol Psychiatry. 2022 Apr 14. pii: 10.1038/s41380-022-01502.
    PubMed     Abstract available


  46. ALMULLA AF, Vasupanrajit A, Tunvirachaisakul C, Al-Hakeim HK, et al
    The tryptophan catabolite or kynurenine pathway in schizophrenia: meta-analysis reveals dissociations between central, serum, and plasma compartments.
    Mol Psychiatry. 2022 Apr 14. pii: 10.1038/s41380-022-01552.
    PubMed     Abstract available


  47. PALANIYAPPAN L
    Adaptive changes to oxidative stress in schizophrenia.
    Mol Psychiatry. 2022 Apr 8. pii: 10.1038/s41380-022-01550.
    PubMed    


  48. AYORA M, Fraguas D, Abregu-Crespo R, Recio S, et al
    Leukocyte telomere length in patients with schizophrenia and related disorders: a meta-analysis of case-control studies.
    Mol Psychiatry. 2022 Apr 7. pii: 10.1038/s41380-022-01541.
    PubMed     Abstract available


  49. SONG J, Yao S, Kowalec K, Lu Y, et al
    The impact of educational attainment, intelligence and intellectual disability on schizophrenia: a Swedish population-based register and genetic study.
    Mol Psychiatry. 2022 Apr 5. pii: 10.1038/s41380-022-01500.
    PubMed     Abstract available


  50. BELLON A, Feuillet V, Cortez-Resendiz A, Mouaffak F, et al
    Dopamine-induced pruning in monocyte-derived-neuronal-like cells (MDNCs) from patients with schizophrenia.
    Mol Psychiatry. 2022 Apr 1. pii: 10.1038/s41380-022-01514.
    PubMed     Abstract available


  51. REN D, Wei X, Lin L, Yuan F, et al
    A novel heterozygous missense variant of the ARID4A gene identified in Han Chinese families with schizophrenia-diagnosed siblings that interferes with DNA-binding activity.
    Mol Psychiatry. 2022 Apr 1. pii: 10.1038/s41380-022-01530.
    PubMed     Abstract available


  52. PERZEL MANDELL KA, Eagles NJ, Deep-Soboslay A, Tao R, et al
    Molecular phenotypes associated with antipsychotic drugs in the human caudate nucleus.
    Mol Psychiatry. 2022;27:2061-2067.
    PubMed     Abstract available


    March 2022
  53. HENKEL ND, Wu X, O'Donovan SM, Devine EA, et al
    Schizophrenia: a disorder of broken brain bioenergetics.
    Mol Psychiatry. 2022 Mar 9. pii: 10.1038/s41380-022-01494.
    PubMed     Abstract available


  54. MEALER RG, Williams SE, Noel M, Yang B, et al
    The schizophrenia-associated variant in SLC39A8 alters protein glycosylation in the mouse brain.
    Mol Psychiatry. 2022 Mar 8. pii: 10.1038/s41380-022-01490.
    PubMed     Abstract available


    February 2022
  55. MCGUINNESS AJ, Davis JA, Dawson SL, Loughman A, et al
    A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophrenia.
    Mol Psychiatry. 2022 Feb 22. pii: 10.1038/s41380-022-01456.
    PubMed     Abstract available


  56. HWANG I, Kim BS, Ko HR, Cho S, et al
    Cerebellar dysfunction and schizophrenia-like behavior in Ebp1-deficient mice.
    Mol Psychiatry. 2022 Feb 15. pii: 10.1038/s41380-022-01458.
    PubMed     Abstract available


  57. DI BIASE MA, Geaghan MP, Reay WR, Seidlitz J, et al
    Cell type-specific manifestations of cortical thickness heterogeneity in schizophrenia.
    Mol Psychiatry. 2022 Feb 10. pii: 10.1038/s41380-022-01460.
    PubMed     Abstract available


  58. OLISLAGERS M, Rademaker K, Adan RAH, Lin BD, et al
    Comprehensive analyses of RNA-seq and genome-wide data point to enrichment of neuronal cell type subsets in neuropsychiatric disorders.
    Mol Psychiatry. 2022;27:947-955.
    PubMed     Abstract available


  59. KIRSCHNER M, Hodzic-Santor B, Antoniades M, Nenadic I, et al
    Cortical and subcortical neuroanatomical signatures of schizotypy in 3004 individuals assessed in a worldwide ENIGMA study.
    Mol Psychiatry. 2022;27:1167-1176.
    PubMed     Abstract available


    January 2022
  60. MERIKANGAS AK, Shelly M, Knighton A, Kotler N, et al
    What genes are differentially expressed in individuals with schizophrenia? A systematic review.
    Mol Psychiatry. 2022 Jan 28. pii: 10.1038/s41380-021-01420.
    PubMed     Abstract available


  61. EL KHOUEIRY C, Cabungcal JH, Rovo Z, Fournier M, et al
    Developmental oxidative stress leads to T-type Ca(2+) channel hypofunction in thalamic reticular nucleus of mouse models pertinent to schizophrenia.
    Mol Psychiatry. 2022 Jan 25. pii: 10.1038/s41380-021-01425.
    PubMed     Abstract available


  62. LI W, Lv L, Luo XJ
    In vivo study sheds new light on the dendritic spine pathology hypothesis of schizophrenia.
    Mol Psychiatry. 2022 Jan 25. pii: 10.1038/s41380-022-01449.
    PubMed    


  63. SIMPSON EH, Gallo EF, Balsam PD, Javitch JA, et al
    How changes in dopamine D2 receptor levels alter striatal circuit function and motivation.
    Mol Psychiatry. 2022;27:436-444.
    PubMed     Abstract available


  64. NAIR PC, Miners JO, McKinnon RA, Langmead CJ, et al
    Binding of SEP-363856 within TAAR1 and the 5HT1A receptor: implications for the design of novel antipsychotic drugs.
    Mol Psychiatry. 2022;27:88-94.
    PubMed     Abstract available


    December 2021
  65. ERADY C, Amin K, Onilogbo TOAE, Tomasik J, et al
    Novel open reading frames in human accelerated regions and transposable elements reveal new leads to understand schizophrenia and bipolar disorder.
    Mol Psychiatry. 2021 Dec 23. pii: 10.1038/s41380-021-01405.
    PubMed     Abstract available


  66. HASSAN L, Peek N, Lovell K, Carvalho AF, et al
    Disparities in COVID-19 infection, hospitalisation and death in people with schizophrenia, bipolar disorder, and major depressive disorder: a cohort study of the UK Biobank.
    Mol Psychiatry. 2021 Dec 7. pii: 10.1038/s41380-021-01344.
    PubMed     Abstract available


  67. BAGAUTDINOVA J, Zoller D, Schaer M, Padula MC, et al
    Altered cortical thickness development in 22q11.2 deletion syndrome and association with psychotic symptoms.
    Mol Psychiatry. 2021;26:7671-7678.
    PubMed     Abstract available


    November 2021
  68. ALKELAI A, Greenbaum L, Docherty AR, Shabalin AA, et al
    The benefit of diagnostic whole genome sequencing in schizophrenia and other psychotic disorders.
    Mol Psychiatry. 2021 Nov 19. pii: 10.1038/s41380-021-01383.
    PubMed     Abstract available


  69. ZHANG R, Sjolander A, Ploner A, Lu D, et al
    Novel disease associations with schizophrenia genetic risk revealed in ~400,000 UK Biobank participants.
    Mol Psychiatry. 2021 Nov 19. pii: 10.1038/s41380-021-01387.
    PubMed     Abstract available


  70. NOTARAS M, Lodhi A, Dundar F, Collier P, et al
    Schizophrenia is defined by cell-specific neuropathology and multiple neurodevelopmental mechanisms in patient-derived cerebral organoids.
    Mol Psychiatry. 2021 Nov 17. pii: 10.1038/s41380-021-01316.
    PubMed     Abstract available


  71. EISENBERG DP, Kohn PD, Hegarty CE, Smith NR, et al
    Clinical correlation but no elevation of striatal dopamine synthesis capacity in two independent cohorts of medication-free individuals with schizophrenia.
    Mol Psychiatry. 2021 Nov 17. pii: 10.1038/s41380-021-01337.
    PubMed     Abstract available


  72. PLAVEN-SIGRAY P, Ikonen Victorsson P, Santillo A, Matheson GJ, et al
    Thalamic dopamine D2-receptor availability in schizophrenia: a study on antipsychotic-naive patients with first-episode psychosis and a meta-analysis.
    Mol Psychiatry. 2021 Nov 10. pii: 10.1038/s41380-021-01349.
    PubMed     Abstract available


  73. CUENOD M, Steullet P, Cabungcal JH, Dwir D, et al
    Caught in vicious circles: a perspective on dynamic feed-forward loops driving oxidative stress in schizophrenia.
    Mol Psychiatry. 2021 Nov 10. pii: 10.1038/s41380-021-01374.
    PubMed     Abstract available


  74. ZHOU X
    Over-representation of potential SP4 target genes within schizophrenia-risk genes.
    Mol Psychiatry. 2021 Nov 8. pii: 10.1038/s41380-021-01376.
    PubMed     Abstract available


  75. SELLGREN CM, Imbeault S, Larsson MK, Oliveros A, et al
    Correction: GRK3 deficiency elicits brain immune activation and psychosis.
    Mol Psychiatry. 2021 Nov 8. pii: 10.1038/s41380-021-01371.
    PubMed    


  76. CAMPEAU A, Mills RH, Stevens T, Rossitto LA, et al
    Multi-omics of human plasma reveals molecular features of dysregulated inflammation and accelerated aging in schizophrenia.
    Mol Psychiatry. 2021 Nov 5. pii: 10.1038/s41380-021-01339.
    PubMed     Abstract available


  77. GAO Y, Fan Y, Yang Z, Ma Q, et al
    Systems biological assessment of altered cytokine responses to bacteria and fungi reveals impaired immune functionality in schizophrenia.
    Mol Psychiatry. 2021 Nov 2. pii: 10.1038/s41380-021-01362.
    PubMed     Abstract available


  78. LI Q, Wang Z, Zong L, Ye L, et al
    Allele-specific DNA methylation maps in monozygotic twins discordant for psychiatric disorders reveal that disease-associated switching at the EIPR1 regulatory loci modulates neural function.
    Mol Psychiatry. 2021;26:6630-6642.
    PubMed     Abstract available


    October 2021
  79. CHAN SY, Brady RO, Lewandowski KE, Higgins A, et al
    Dynamic and progressive changes in thalamic functional connectivity over the first five years of psychosis.
    Mol Psychiatry. 2021 Oct 25. pii: 10.1038/s41380-021-01319.
    PubMed     Abstract available


  80. KHADIMALLAH I, Jenni R, Cabungcal JH, Cleusix M, et al
    Mitochondrial, exosomal miR137-COX6A2 and gamma synchrony as biomarkers of parvalbumin interneurons, psychopathology, and neurocognition in schizophrenia.
    Mol Psychiatry. 2021 Oct 22. pii: 10.1038/s41380-021-01313.
    PubMed     Abstract available


  81. WOLF DH, Zheng D, Kohler C, Turetsky BI, et al
    Effect of mGluR2 positive allosteric modulation on frontostriatal working memory activation in schizophrenia.
    Mol Psychiatry. 2021 Oct 20. pii: 10.1038/s41380-021-01320.
    PubMed     Abstract available


  82. YANG K, Longo L, Narita Z, Cascella N, et al
    A multimodal study of a first episode psychosis cohort: potential markers of antipsychotic treatment resistance.
    Mol Psychiatry. 2021 Oct 12. pii: 10.1038/s41380-021-01331.
    PubMed     Abstract available


    September 2021
  83. LUO C, Pi X, Hu N, Wang X, et al
    Subtypes of schizophrenia identified by multi-omic measures associated with dysregulated immune function.
    Mol Psychiatry. 2021 Sep 29. pii: 10.1038/s41380-021-01308.
    PubMed     Abstract available


  84. NAKAHARA T, Tsugawa S, Noda Y, Ueno F, et al
    Glutamatergic and GABAergic metabolite levels in schizophrenia-spectrum disorders: a meta-analysis of (1)H-magnetic resonance spectroscopy studies.
    Mol Psychiatry. 2021 Sep 28. pii: 10.1038/s41380-021-01297.
    PubMed     Abstract available


  85. SAARENTAUS EC, Havulinna AS, Mars N, Ahola-Olli A, et al
    Polygenic burden has broader impact on health, cognition, and socioeconomic outcomes than most rare and high-risk copy number variants.
    Mol Psychiatry. 2021;26:4884-4895.
    PubMed     Abstract available


  86. JIA X, Goes FS, Locke AE, Palmer D, et al
    Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder.
    Mol Psychiatry. 2021;26:5239-5250.
    PubMed     Abstract available


    August 2021
  87. STAUFFER EM, Bethlehem RAI, Warrier V, Murray GK, et al
    Grey and white matter microstructure is associated with polygenic risk for schizophrenia.
    Mol Psychiatry. 2021 Aug 30. pii: 10.1038/s41380-021-01260.
    PubMed     Abstract available


  88. LI Y, Li S, Liu J, Huo Y, et al
    The schizophrenia susceptibility gene NAGA regulates dendritic spine density: further evidence for the dendritic spine pathology of schizophrenia.
    Mol Psychiatry. 2021 Aug 10. pii: 10.1038/s41380-021-01261.
    PubMed    


  89. RAUBER S, Heming M, Repple J, Ruland T, et al
    Cerebrospinal fluid flow cytometry distinguishes psychosis spectrum disorders from differential diagnoses.
    Mol Psychiatry. 2021 Aug 6. pii: 10.1038/s41380-021-01244.
    PubMed     Abstract available


  90. TAKAYANAGI Y, Ishizuka K, Laursen TM, Yukitake H, et al
    From population to neuron: exploring common mediators for metabolic problems and mental illnesses.
    Mol Psychiatry. 2021;26:3931-3942.
    PubMed     Abstract available


  91. NI C, Jiang W, Wang Z, Wang Z, et al
    LncRNA-AC006129.1 reactivates a SOCS3-mediated anti-inflammatory response through DNA methylation-mediated CIC downregulation in schizophrenia.
    Mol Psychiatry. 2021;26:4511-4528.
    PubMed     Abstract available


  92. CLEYNEN I, Engchuan W, Hestand MS, Heung T, et al
    Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion.
    Mol Psychiatry. 2021;26:4496-4510.
    PubMed     Abstract available


  93. GOBSHTIS N, Tfilin M, Fraifeld VE, Turgeman G, et al
    Transplantation of mesenchymal stem cells causes long-term alleviation of schizophrenia-like behaviour coupled with increased neurogenesis.
    Mol Psychiatry. 2021;26:4448-4463.
    PubMed     Abstract available


  94. GREENING DW, Notaras M, Chen M, Xu R, et al
    Chronic methamphetamine interacts with BDNF Val66Met to remodel psychosis pathways in the mesocorticolimbic proteome.
    Mol Psychiatry. 2021;26:4431-4447.
    PubMed     Abstract available


  95. HARRISON PJ, Hall N, Mould A, Al-Juffali N, et al
    Cellular calcium in bipolar disorder: systematic review and meta-analysis.
    Mol Psychiatry. 2021;26:4106-4116.
    PubMed     Abstract available


  96. BORGAN F, O'Daly O, Veronese M, Reis Marques T, et al
    The neural and molecular basis of working memory function in psychosis: a multimodal PET-fMRI study.
    Mol Psychiatry. 2021;26:4464-4474.
    PubMed     Abstract available


  97. KOWALEC K, Lu Y, Sariaslan A, Song J, et al
    Increased schizophrenia family history burden and reduced premorbid IQ in treatment-resistant schizophrenia: a Swedish National Register and Genomic Study.
    Mol Psychiatry. 2021;26:4487-4495.
    PubMed     Abstract available


    July 2021
  98. LIU Z, Palaniyappan L, Wu X, Zhang K, et al
    Resolving heterogeneity in schizophrenia through a novel systems approach to brain structure: individualized structural covariance network analysis.
    Mol Psychiatry. 2021 Jul 28. pii: 10.1038/s41380-021-01229.
    PubMed     Abstract available


  99. MURPHY CE, Weickert CS
    A new suspect in the unsolved case of neuroinflammation in schizophrenia.
    Mol Psychiatry. 2021 Jul 20. pii: 10.1038/s41380-021-01225.
    PubMed    


  100. WU X, Shukla R, Alganem K, Zhang X, et al
    Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity.
    Mol Psychiatry. 2021 Jul 16. pii: 10.1038/s41380-021-01205.
    PubMed     Abstract available


  101. HEURICH M, Focking M, Mongan D, Cagney G, et al
    Dysregulation of complement and coagulation pathways: emerging mechanisms in the development of psychosis.
    Mol Psychiatry. 2021 Jul 5. pii: 10.1038/s41380-021-01197.
    PubMed     Abstract available


  102. SHA Z, Schijven D, Francks C
    Patterns of brain asymmetry associated with polygenic risks for autism and schizophrenia implicate language and executive functions but not brain masculinization.
    Mol Psychiatry. 2021 Jul 1. pii: 10.1038/s41380-021-01204.
    PubMed     Abstract available


  103. STEIXNER-KUMAR AA, Daguano Gastaldi V, Seidel J, Rosenberger A, et al
    Preadult polytoxicomania-strong environmental underpinnings and first genetic hints.
    Mol Psychiatry. 2021;26:3211-3222.
    PubMed     Abstract available


  104. CLIFTON NE, Rees E, Holmans PA, Pardinas AF, et al
    Genetic association of FMRP targets with psychiatric disorders.
    Mol Psychiatry. 2021;26:2977-2990.
    PubMed     Abstract available


    June 2021
  105. ZHU X, Cabungcal JH, Cuenod M, Uliana DL, et al
    Thalamic reticular nucleus impairments and abnormal prefrontal control of dopamine system in a developmental model of schizophrenia: prevention by N-acetylcysteine.
    Mol Psychiatry. 2021 Jun 30. pii: 10.1038/s41380-021-01198.
    PubMed     Abstract available


  106. GUAN F, Ni T, Zhu W, Williams LK, et al
    Integrative omics of schizophrenia: from genetic determinants to clinical classification and risk prediction.
    Mol Psychiatry. 2021 Jun 30. pii: 10.1038/s41380-021-01201.
    PubMed     Abstract available


  107. GAO WJ, Yang SS, Mack NR, Chamberlin LA, et al
    Aberrant maturation and connectivity of prefrontal cortex in schizophrenia-contribution of NMDA receptor development and hypofunction.
    Mol Psychiatry. 2021 Jun 23. pii: 10.1038/s41380-021-01196.
    PubMed     Abstract available


  108. ROGDAKI M, Devroye C, Ciampoli M, Veronese M, et al
    Correction: Striatal dopaminergic alterations in individuals with copy number variants at the 22q11.2 genetic locus and their implications for psychosis risk: a [18F]-DOPA PET study.
    Mol Psychiatry. 2021 Jun 22. pii: 10.1038/s41380-021-01192.
    PubMed    


  109. RADHAKRISHNAN R, Skosnik PD, Ranganathan M, Naganawa M, et al
    In vivo evidence of lower synaptic vesicle density in schizophrenia.
    Mol Psychiatry. 2021 Jun 16. pii: 10.1038/s41380-021-01184.
    PubMed     Abstract available


  110. DEMICHELE-SWEET MAA, Klei L, Creese B, Harwood JC, et al
    Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease.
    Mol Psychiatry. 2021 Jun 10. pii: 10.1038/s41380-021-01152.
    PubMed     Abstract available


  111. TIGARET CM, Lin TE, Morrell ER, Sykes L, et al
    Neurotrophin receptor activation rescues cognitive and synaptic abnormalities caused by hemizygosity of the psychiatric risk gene Cacna1c.
    Mol Psychiatry. 2021;26:1748-1760.
    PubMed     Abstract available


  112. BYRNE EM, Zhu Z, Qi T, Skene NG, et al
    Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders.
    Mol Psychiatry. 2021;26:2070-2081.
    PubMed     Abstract available


  113. PEREZ JM, Berto S, Gleason K, Ghose S, et al
    Hippocampal subfield transcriptome analysis in schizophrenia psychosis.
    Mol Psychiatry. 2021;26:2577-2589.
    PubMed     Abstract available


  114. CAO H, Zhou H, Cannon TD
    Functional connectome-wide associations of schizophrenia polygenic risk.
    Mol Psychiatry. 2021;26:2553-2561.
    PubMed     Abstract available


  115. MA L, Shcherbina A, Chetty S
    Variations and expression features of CYP2D6 contribute to schizophrenia risk.
    Mol Psychiatry. 2021;26:2605-2615.
    PubMed     Abstract available


    May 2021
  116. WEISSLEDER C, North HF, Bitar M, Fullerton JM, et al
    Reduced adult neurogenesis is associated with increased macrophages in the subependymal zone in schizophrenia.
    Mol Psychiatry. 2021 May 31. pii: 10.1038/s41380-021-01149.
    PubMed     Abstract available


  117. DI BIASE MA, Cetin-Karayumak S, Lyall AE, Zalesky A, et al
    White matter changes in psychosis risk relate to development and are not impacted by the transition to psychosis.
    Mol Psychiatry. 2021 May 24. pii: 10.1038/s41380-021-01128.
    PubMed     Abstract available


  118. CHADHA R, Alganem K, Mccullumsmith RE, Meador-Woodruff JH, et al
    mTOR kinase activity disrupts a phosphorylation signaling network in schizophrenia brain.
    Mol Psychiatry. 2021 May 14. pii: 10.1038/s41380-021-01135.
    PubMed     Abstract available


  119. KARIMI B, Silwal P, Booth S, Padmanabhan N, et al
    Schizophrenia-associated LRRTM1 regulates cognitive behavior through controlling synaptic function in the mediodorsal thalamus.
    Mol Psychiatry. 2021 May 12. pii: 10.1038/s41380-021-01146.
    PubMed     Abstract available


  120. ROGDAKI M, Devroye C, Ciampoli M, Veronese M, et al
    Striatal dopaminergic alterations in individuals with copy number variants at the 22q11.2 genetic locus and their implications for psychosis risk: a [18F]-DOPA PET study.
    Mol Psychiatry. 2021 May 12. pii: 10.1038/s41380-021-01108.
    PubMed     Abstract available


  121. SELLGREN CM, Imbeault S, Larsson MK, Oliveros A, et al
    GRK3 deficiency elicits brain immune activation and psychosis.
    Mol Psychiatry. 2021 May 12. pii: 10.1038/s41380-021-01106.
    PubMed     Abstract available


    April 2021
  122. LI Y, Ma C, Li W, Yang Y, et al
    A missense variant in NDUFA6 confers schizophrenia risk by affecting YY1 binding and NAGA expression.
    Mol Psychiatry. 2021 Apr 30. pii: 10.1038/s41380-021-01125.
    PubMed     Abstract available


  123. SHEN M, Guo Y, Dong Q, Gao Y, et al
    FXR1 regulation of parvalbumin interneurons in the prefrontal cortex is critical for schizophrenia-like behaviors.
    Mol Psychiatry. 2021 Apr 16. pii: 10.1038/s41380-021-01096.
    PubMed     Abstract available


  124. DRUART M, Nosten-Bertrand M, Poll S, Crux S, et al
    Elevated expression of complement C4 in the mouse prefrontal cortex causes schizophrenia-associated phenotypes.
    Mol Psychiatry. 2021 Apr 9. pii: 10.1038/s41380-021-01081.
    PubMed     Abstract available


  125. ANDLAUER TFM, Guzman-Parra J, Streit F, Strohmaier J, et al
    Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders.
    Mol Psychiatry. 2021;26:1286-1298.
    PubMed     Abstract available


  126. LEGGIO GM, Torrisi SA, Mastrogiacomo R, Mauro D, et al
    The epistatic interaction between the dopamine D3 receptor and dysbindin-1 modulates higher-order cognitive functions in mice and humans.
    Mol Psychiatry. 2021;26:1272-1285.
    PubMed     Abstract available


    March 2021
  127. SINHA V, Ukkola-Vuoti L, Ortega-Alonso A, Torniainen-Holm M, et al
    Variants in regulatory elements of PDE4D associate with major mental illness in the Finnish population.
    Mol Psychiatry. 2021;26:816-824.
    PubMed     Abstract available


    February 2021
  128. RATHJE M, Waxman H, Benoit M, Tammineni P, et al
    Genetic variants in the bipolar disorder risk locus SYNE1 that affect CPG2 expression and protein function.
    Mol Psychiatry. 2021;26:508-523.
    PubMed     Abstract available


    January 2021
  129. NORTHOFF G, Hirjak D, Wolf RC, Magioncalda P, et al
    All roads lead to the motor cortex: psychomotor mechanisms and their biochemical modulation in psychiatric disorders.
    Mol Psychiatry. 2021;26:92-102.
    PubMed     Abstract available


Thank you for your interest in scientific medicine.


AMEDEO Schizophrenia is free of charge.
This policy is made possible thanks to a media sponsorship by Boehringer Ingelheim.

Design: