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  Sepsis

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Articles published in Crit Care Med

Retrieve available abstracts of 204 articles:
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Single Articles


    February 2024
  1. SHIME N, Inagawa T, MacLaren G
    Time to Reexamine the Definition of Sepsis?
    Crit Care Med. 2024;52:e107-e108.
    PubMed    


  2. MASLOVE DM
    Echocardiography in the Management of Sepsis: Not All Black and White.
    Crit Care Med. 2024;52:348-350.
    PubMed    


  3. BHAVANI SV, Mohr N
    Saved by the Bell-Automated Paging Alerts to Improve Sepsis Bundle Compliance.
    Crit Care Med. 2024;52:340-342.
    PubMed    


  4. DE BACKER D, Deutschman CS, Hellman J, Myatra SN, et al
    Surviving Sepsis Campaign Research Priorities 2023.
    Crit Care Med. 2024;52:268-296.
    PubMed     Abstract available


  5. BLANK SP, Blank RM
    Echocardiography Does not Reduce Mortality in Sepsis: A Re-Evaluation Using the Medical Information Mart for Intensive Care IV Dataset.
    Crit Care Med. 2024;52:248-257.
    PubMed     Abstract available


    January 2024
  6. CHAUDHURI D, Nei AM, Rochwerg B, Balk RA, et al
    2024 Focused Update: Guidelines on Use of Corticosteroids in Sepsis, Acute Respiratory Distress Syndrome, and Community-Acquired Pneumonia.
    Crit Care Med. 2024 Jan 19. doi: 10.1097/CCM.0000000000006172.
    PubMed     Abstract available


  7. CHAUDHURI D, Nei AM, Rochwerg B, Balk RA, et al
    Executive Summary: Guidelines on Use of Corticosteroids in Critically Ill Patients With Sepsis, Acute Respiratory Distress Syndrome, and Community-Acquired Pneumonia Focused Update 2024.
    Crit Care Med. 2024 Jan 19. doi: 10.1097/CCM.0000000000006171.
    PubMed    


    December 2023
  8. LEISMAN DE, Deng H, Lee AH, Flynn MH, et al
    Effect of Automated Real-Time Feedback on Early-Sepsis Care: A Pragmatic Clinical Trial.
    Crit Care Med. 2023 Dec 13. doi: 10.1097/CCM.0000000000006057.
    PubMed     Abstract available


  9. JHA AK
    Immediate Fluid Bolus or Norepinephrine in Endotoxic Shock.
    Crit Care Med. 2023;51:e279-e280.
    PubMed    


  10. ZHAO JO, Patel BK, Krishack P, Stutz MR, et al
    Identification of Clinically Significant Cytokine Signature Clusters in Patients With Septic Shock.
    Crit Care Med. 2023;51:e253-e263.
    PubMed     Abstract available


  11. DONY CA, Illipparambil LC, Maeda T, Mroczek SK, et al
    Plasma Nitric Oxide Consumption Is Elevated and Associated With Adverse Outcomes in Critically Ill Patients.
    Crit Care Med. 2023;51:1706-1715.
    PubMed     Abstract available


  12. PODD BS, Banks RK, Reeder R, Telford R, et al
    Early, Persistent Lymphopenia Is Associated With Prolonged Multiple Organ Failure and Mortality in Septic Children.
    Crit Care Med. 2023;51:1766-1776.
    PubMed     Abstract available


    November 2023
  13. BUSSE LW, Schaich CL, Chappell MC, McCurdy MT, et al
    Association of Active Renin Content With Mortality in Critically Ill Patients: A Post hoc Analysis of the Vitamin C, Thiamine, and Steroids in Sepsis Trial.
    Crit Care Med. 2023 Nov 10. doi: 10.1097/CCM.0000000000006095.
    PubMed     Abstract available


  14. FAN TH, Premraj L, Roberts J, Lydston M, et al
    In-Hospital Neurologic Complications, Neuromonitoring, and Long-Term Neurologic Outcomes in Patients With Sepsis: A Systematic Review and Meta-Analysis.
    Crit Care Med. 2023 Nov 3. doi: 10.1097/CCM.0000000000006096.
    PubMed     Abstract available


  15. RUAN H, Zhang Q, Ran X
    Unraveling the Obesity Paradox in Sepsis Patients: Insights Into the Role of Body Composition and Adipose Distribution.
    Crit Care Med. 2023;51:e249-e250.
    PubMed    


  16. ANESI GL, Admon AJ
    Unpacking Regionalization of Sepsis Care Using Hospital Capability Assessments.
    Crit Care Med. 2023;51:1594-1596.
    PubMed    


  17. PALMER ES, Agus MSD
    Running Wide Open: Strong Evidence for Bolus Fluids Selection in Pediatric Sepsis.
    Crit Care Med. 2023;51:1587-1589.
    PubMed    


  18. SANKAR J, Muralidharan J, Lalitha AV, Rameshkumar R, et al
    Multiple Electrolytes Solution Versus Saline as Bolus Fluid for Resuscitation in Pediatric Septic Shock: A Multicenter Randomized Clinical Trial.
    Crit Care Med. 2023;51:1449-1460.
    PubMed     Abstract available


  19. MAYER S, Bonhag C, Jenkins P, Cornett B, et al
    Probiotic-Associated Central Venous Catheter Bloodstream Infections Lead to Increased Mortality in the ICU.
    Crit Care Med. 2023;51:1469-1478.
    PubMed     Abstract available


    October 2023
  20. HONORE PM, Bousbiat I, Perriens E, Orman A, et al
    Potential Confounders in Study Stating That Levels of Prokineticin-2 Were Significantly Higher in Septic Shock Than Sepsis.
    Crit Care Med. 2023;51:e206-e207.
    PubMed    


  21. SCRUTH E
    Life After Sepsis: The Journey Continues.
    Crit Care Med. 2023;51:1439-1441.
    PubMed    


    September 2023
  22. BARLETTA JF
    Empiric Carbapenem Therapy for Sepsis: Are We Winning the Battle at the Expense of the War?
    Crit Care Med. 2023;51:1275-1277.
    PubMed    


  23. LAWANDI A
    Bloodstream Infections in Sepsis: Better the Devil You Know.
    Crit Care Med. 2023;51:1261-1263.
    PubMed    


    August 2023
  24. CUMMINGS MJ, Bakamutumaho B, Tomoiaga AS, Owor N, et al
    A Transcriptomic Classifier Model Identifies High-Risk Endotypes in a Prospective Study of Sepsis in Uganda.
    Crit Care Med. 2023 Aug 7. doi: 10.1097/CCM.0000000000006023.
    PubMed     Abstract available


  25. LEE DH
    Obesity Paradox in Sepsis: Role of Adipose Tissue in Storing Mitochondrial Toxins.
    Crit Care Med. 2023;51:e172-e174.
    PubMed    


  26. LYONS NB, Proctor KG
    Are the Outcomes of a Pig Endotoxemia Model Applicable to Human Sepsis?
    Crit Care Med. 2023;51:1102-1104.
    PubMed    


  27. KALIL AC, Simpson SQ
    Vitamin C and Sepsis: Is Bayesian Reanalysis Useful to Translate the Results of Frequentist Randomized Trials?
    Crit Care Med. 2023;51:1100-1102.
    PubMed    


  28. OSPINA-TASCON GA, Aldana JL, Garcia Marin AF, Calderon-Tapia LE, et al
    Immediate Norepinephrine in Endotoxic Shock: Effects on Regional and Microcirculatory Flow.
    Crit Care Med. 2023;51:e157-e168.
    PubMed     Abstract available


    July 2023
  29. CHEN JJ, Lai PC, Lee TH, Huang YT, et al
    Blood Purification for Adult Patients With Severe Infection or Sepsis/Septic Shock: A Network Meta-Analysis of Randomized Controlled Trials.
    Crit Care Med. 2023 Jul 20. doi: 10.1097/CCM.0000000000005991.
    PubMed     Abstract available


  30. LAWANDI A, Oshiro M, Warner S, Diao G, et al
    Reliability of Admission Procalcitonin Testing for Capturing Bacteremia Across the Sepsis Spectrum: Real-World Utilization and Performance Characteristics, 65 U.S. Hospitals, 2008-2017.
    Crit Care Med. 2023 Jul 3. doi: 10.1097/CCM.0000000000005968.
    PubMed     Abstract available


    June 2023
  31. OFOMA UR, Deych E, Mohr NM, Walkey A, et al
    The Relationship Between Hospital Capability and Mortality in Sepsis: Development of a Sepsis-Related Hospital Capability Index.
    Crit Care Med. 2023 Jun 20. doi: 10.1097/CCM.0000000000005973.
    PubMed     Abstract available


  32. KUREMATSU K, Ikematsu Y
    Quality of Life of Sepsis Survivors.
    Crit Care Med. 2023 Jun 14. doi: 10.1097/CCM.0000000000005944.
    PubMed     Abstract available


  33. WARD A, Chemparathy A, Seneviratne M, Gaskari S, et al
    The Association Between Central Line-Associated Bloodstream Infection and Central Line Access.
    Crit Care Med. 2023;51:787-796.
    PubMed     Abstract available


    May 2023
  34. UMEMURA Y, Yamakawa K, Tanaka Y, Yoshimura J, et al
    Efficacy of Carbapenems Compared With Noncarbapenem Broad-Spectrum Beta-Lactam Antibiotics as Initial Antibiotic Therapy Against Sepsis: A Nationwide Observational Study.
    Crit Care Med. 2023 May 26. doi: 10.1097/CCM.0000000000005932.
    PubMed     Abstract available


    April 2023
  35. OHBE H, Sasabuchi Y, Doi K, Matsui H, et al
    Association Between Levels of Intensive Care and In-Hospital Mortality in Patients Hospitalized for Sepsis Stratified by Sequential Organ Failure Assessment Scores.
    Crit Care Med. 2023 Apr 28. doi: 10.1097/CCM.0000000000005886.
    PubMed     Abstract available


  36. WARDI G, Owens R, Josef C, Malhotra A, et al
    Bringing the Promise of Artificial Intelligence to Critical Care: What the Experience With Sepsis Analytics Can Teach Us.
    Crit Care Med. 2023 Apr 26. doi: 10.1097/CCM.0000000000005894.
    PubMed    


  37. ANGRIMAN F, Muttalib F, Lamontagne F, Adhikari NKJ, et al
    IV Vitamin C in Adults With Sepsis: A Bayesian Reanalysis of a Randomized Controlled Trial.
    Crit Care Med. 2023 Apr 7. doi: 10.1097/CCM.0000000000005871.
    PubMed     Abstract available


  38. OHNUMA T, Chihara S, Costin B, Treggiari M, et al
    Epidemiology, Resistance Profiles, and Outcomes of Bloodstream Infections in Community-Onset Sepsis in the United States.
    Crit Care Med. 2023 Apr 5. doi: 10.1097/CCM.0000000000005870.
    PubMed     Abstract available


  39. BHAVANI SV
    A Need for Prospective Long-Term Data to Characterize Cardiovascular Risk Factors in Sepsis Survivors.
    Crit Care Med. 2023;51:549-550.
    PubMed    


  40. DELLINGER RP, Rhodes A, Evans L, Alhazzani W, et al
    Surviving Sepsis Campaign.
    Crit Care Med. 2023;51:431-444.
    PubMed    


  41. JOUFFROY R, Gueye P, Vivien B
    Turning Back the Clock: Prehospital Antibiotics for Patients With Septic Shock: Let Us Act at the Right Time.
    Crit Care Med. 2023;51:e97-e98.
    PubMed    


    March 2023
  42. HUANG YH, Chen CJ, Shao SC, Li CH, et al
    Comparison of the Diagnostic Accuracies of Monocyte Distribution Width, Procalcitonin, and C-Reactive Protein for Sepsis: A Systematic Review and Meta-Analysis.
    Crit Care Med. 2023 Mar 6. doi: 10.1097/CCM.0000000000005820.
    PubMed     Abstract available


    February 2023
  43. ANGRIMAN F, Rosella LC, Lawler PR, Ko DT, et al
    Risk Factors for Major Cardiovascular Events in Adult Sepsis Survivors: A Population-Based Cohort Study.
    Crit Care Med. 2023 Feb 15. doi: 10.1097/CCM.0000000000005793.
    PubMed     Abstract available


  44. YEO HJ, Kim TH, Jang JH, Jeon K, et al
    Obesity Paradox and Functional Outcomes in Sepsis: A Multicenter Prospective Study.
    Crit Care Med. 2023 Feb 10. doi: 10.1097/CCM.0000000000005801.
    PubMed     Abstract available


  45. MONTOYA C
    Clarification of Key Points in a Study Evaluating the Association of Metformin and Mortality in Patients With Sepsis and Type 2 Diabetes.
    Crit Care Med. 2023;51:e60.
    PubMed    


  46. HONORE PM, Redant S, Djimafo P, Blackman S, et al
    After the Rebranding and Cost Increase, the Use of Vasopressin Continues to Increase Yearly Especially in Case of Acute Kidney Injury With Septic Shock: Is There Recent Data Justifying It?
    Crit Care Med. 2023;51:e68-e69.
    PubMed    


    December 2022
  47. ZHOU X, Weng J, Xu Z, Yang J, et al
    Effect of Admission and Discharge Times on Hospital Mortality in Patients With Sepsis.
    Crit Care Med. 2022 Dec 26. doi: 10.1097/CCM.0000000000005767.
    PubMed     Abstract available


  48. HAGIYA H
    Clinical Utility of Therapeutic Hyperthermia for Patients With Sepsis Needs Further Investigation.
    Crit Care Med. 2022;50:e811-e812.
    PubMed    



  49. Prehospital Bundle of Care Based on Antibiotic Therapy and Hemodynamic Optimization Is Associated With a 30-Day Mortality Decrease in Patients With Septic Shock: Erratum.
    Crit Care Med. 2022;50:e819.
    PubMed    


  50. RYDER JH, Kalil AC
    Of Granularity and Generality: ICU-Onset Bloodstream Infections and the Need for Antimicrobial Stewardship and Infection Prevention.
    Crit Care Med. 2022;50:1828-1830.
    PubMed    


  51. GOUEL-CHERON A, Swihart BJ, Warner S, Mathew L, et al
    Epidemiology of ICU-Onset Bloodstream Infection: Prevalence, Pathogens, and Risk Factors Among 150,948 ICU Patients at 85 U.S. Hospitals.
    Crit Care Med. 2022;50:1725-1736.
    PubMed     Abstract available


    October 2022
  52. HONORE PM, Redant S, Djimafo P, Blackman S, et al
    Potential Confounders in Study Concluding Higher Lactate at Vasopressin Initiation Is Associated With Higher Mortality in Septic Shock.
    Crit Care Med. 2022;50:e775-e776.
    PubMed    


  53. KLOMPAS M, Goldberg SA
    Turning Back the Clock: Prehospital Antibiotics for Patients With Septic Shock.
    Crit Care Med. 2022;50:1537-1540.
    PubMed    


  54. JOUFFROY R, Gilbert B, Tourtier JP, Bloch-Laine E, et al
    Prehospital Bundle of Care Based on Antibiotic Therapy and Hemodynamic Optimization Is Associated With a 30-Day Mortality Decrease in Patients With Septic Shock.
    Crit Care Med. 2022;50:1440-1448.
    PubMed     Abstract available


    September 2022
  55. FIORINO C, Liu Y, Henao R, Ko ER, et al
    Host Gene Expression to Predict Sepsis Progression.
    Crit Care Med. 2022 Sep 30. pii: 00003246-990000000-00045.
    PubMed     Abstract available


  56. HONORE PM, Redant S, Djimafo P, Preseau T, et al
    Therapeutic Hyperthermia Leads to Improved Sepsis Survival: Beware of Potential Confounders!
    Crit Care Med. 2022;50:e734-e735.
    PubMed    


    August 2022
  57. KULA R
    Therapeutic Hyperthermia Is Associated With Improved Survival in Afebrile Critically Ill Patients With Sepsis: A Pilot Randomized Trial.
    Crit Care Med. 2022;50:e693-e694.
    PubMed    


  58. MENDELSOHN SA, Dellinger RP
    Sepsis Awareness Is Good, Please Do Not Let It Be Misunderstood.
    Crit Care Med. 2022;50:1277-1279.
    PubMed    


    July 2022
  59. NATH SS, Nachimuthu N
    Oversight in Executive Summary of Sepsis Guidelines 2021.
    Crit Care Med. 2022;50:e649.
    PubMed    


    June 2022
  60. FEICHTINGER S, de Man A, Dalia AA, Groose MK, et al
    Sepsis and Resuscitation: The Importance of Time.
    Crit Care Med. 2022;50:e615-e616.
    PubMed    


  61. VEZZA T, Victor VM
    Metformin: An Intriguing Protective Agent in Hospitalized Diabetic Patients With Sepsis.
    Crit Care Med. 2022;50:1018-1020.
    PubMed    


  62. SWEENEY DA, Kalil AC
    From Syphilis to Sepsis: Pilot Studies and the Importance of Staying Grounded.
    Crit Care Med. 2022;50:1015-1018.
    PubMed    


  63. HONORE PM, Redant S, Djimafo P, Preseau T, et al
    Wacker et al, Who Conclude That Vitamin C Monotherapy Failed to Significantly Reduce Mortality in Septic Shock Patients: Beware of Potential Confounding Factors!
    Crit Care Med. 2022;50:e611-e612.
    PubMed    


  64. DUGAR S, Khanna AK, Duggal A
    Is Early Vasopressor Safe in Septic Shock?
    Crit Care Med. 2022;50:e599-e600.
    PubMed    


  65. BRUBAKER LS, Saini A, Nguyen TC, Martinez-Vargas M, et al
    Aberrant Fibrin Clot Structure Visualized Ex Vivo in Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection.
    Crit Care Med. 2022;50:e557-e568.
    PubMed     Abstract available


  66. MUKHERJEE R, Tompkins CA, Ostberg NP, Joshi AU, et al
    Drp1/Fis1-Dependent Pathologic Fission and Associated Damaged Extracellular Mitochondria Contribute to Macrophage Dysfunction in Endotoxin Tolerance.
    Crit Care Med. 2022;50:e504-e515.
    PubMed     Abstract available


    May 2022
  67. AGARWAL A, Oczkowski S, Sevransky J
    Phase 2 Vitamin C Sepsis Trials: Another Brick in the (Evidence) Wall?
    Crit Care Med. 2022;50:897-899.
    PubMed    


  68. RHEE C, Septimus EJ
    Heterogeneity in Clinical Presentations of Sepsis: Challenges and Implications for "One-Size-Fits-All" Time-to-Antibiotic Measures.
    Crit Care Med. 2022;50:886-889.
    PubMed    


  69. BARBASH IJ
    Moving Forward: Frailty and Adverse Sepsis Outcomes.
    Crit Care Med. 2022;50:880-882.
    PubMed    


  70. XU R, Miao L, Yang C, Zhu B, et al
    Key Role of Gut Microbiota in Neuroinflammation of Septic Patients.
    Crit Care Med. 2022;50:e500-e502.
    PubMed    


  71. WACKER DA, Burton SL, Berger JP, Hegg AJ, et al
    Evaluating Vitamin C in Septic Shock: A Randomized Controlled Trial of Vitamin C Monotherapy.
    Crit Care Med. 2022;50:e458-e467.
    PubMed     Abstract available


  72. USHER MG, Tourani R, Webber B, Tignanelli CJ, et al
    Patient Heterogeneity and the J-Curve Relationship Between Time-to-Antibiotics and the Outcomes of Patients Admitted With Bacterial Infection.
    Crit Care Med. 2022;50:799-809.
    PubMed     Abstract available


    April 2022
  73. FIEST KM, Krewulak KD, Brundin-Mather R, Leia MP, et al
    Patient, Public, and Healthcare Professional's Sepsis Awareness, Knowledge, and Information Seeking Behaviors: A Scoping Review.
    Crit Care Med. 2022 Apr 29. pii: 00003246-990000000-00008.
    PubMed     Abstract available


  74. DREWRY A, Mohr NM
    Temperature Management in the ICU.
    Crit Care Med. 2022 Apr 15. pii: 00003246-990000000-00005.
    PubMed     Abstract available



  75. Executive Summary: Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic Shock 2021: Erratum.
    Crit Care Med. 2022;50:e413-e414.
    PubMed    


  76. MATSUDA W, Yamamoto M
    How Should We Use Frailty Evaluation for Patients With Sepsis in the Clinical Practice?
    Crit Care Med. 2022;50:e399-e400.
    PubMed    


  77. CONWAY MORRIS A
    New Movement in Sepsis Immunotherapeutics-A Role for Prokineticin 2?
    Crit Care Med. 2022;50:714-716.
    PubMed    


  78. RIMAWI RH, Jacob JT
    Sepsis: The Gift That Keeps Giving.
    Crit Care Med. 2022;50:689-691.
    PubMed    


  79. WANG H, He H, Shen F
    Early Vasopressor Initiation Increases Mortality in Patients With Septic Shock: Less Intensive Intervention or More Critically Ill Patients?
    Crit Care Med. 2022;50:e402-e403.
    PubMed    


  80. CHALFIN DB
    Vasopressor Therapy Early, or Vasopressors Later? Still an Important Question in Septic Shock.
    Crit Care Med. 2022;50:717-718.
    PubMed    


  81. YEO HJ, Lee YS, Kim TH, Jang JH, et al
    Vasopressor Initiation Within 1 Hour of Fluid Loading Is Associated With Increased Mortality in Septic Shock Patients: Analysis of National Registry Data.
    Crit Care Med. 2022;50:e351-e360.
    PubMed     Abstract available


  82. SACHA GL, Kiser TH, Wright GC, Vandivier RW, et al
    Association Between Vasopressin Rebranding and Utilization in Patients With Septic Shock.
    Crit Care Med. 2022;50:644-654.
    PubMed     Abstract available


  83. SACHA GL, Lam SW, Wang L, Duggal A, et al
    Association of Catecholamine Dose, Lactate, and Shock Duration at Vasopressin Initiation With Mortality in Patients With Septic Shock.
    Crit Care Med. 2022;50:614-623.
    PubMed     Abstract available


  84. VENET F, Textoris J, Blein S, Rol ML, et al
    Immune Profiling Demonstrates a Common Immune Signature of Delayed Acquired Immunodeficiency in Patients With Various Etiologies of Severe Injury.
    Crit Care Med. 2022;50:565-575.
    PubMed     Abstract available


  85. PETERS VAN TON AM, Meijer-van Leijsen EMC, Bergkamp MI, Bronkhorst EM, et al
    Risk of Dementia and Structural Brain Changes Following Nonneurological Infections During 9-Year Follow-Up.
    Crit Care Med. 2022;50:554-564.
    PubMed     Abstract available


    March 2022
  86. CHATTERJEE AB
    The IMPACT of Transitional Care Management in Sepsis.
    Crit Care Med. 2022;50:525-527.
    PubMed    


  87. GREEN JM, Taylor HA
    Improving Sepsis Care: Is It Research? Promoting Clarity in a Zone of Confusion.
    Crit Care Med. 2022;50:516-519.
    PubMed    


  88. PATEL JJ, Ortiz-Reyes A, Dhaliwal R, Clarke J, et al
    IV Vitamin C in Critically Ill Patients: A Systematic Review and Meta-Analysis.
    Crit Care Med. 2022;50:e304-e312.
    PubMed     Abstract available


  89. BARICHELLO T, Generoso JS, Dominguini D, Corneo E, et al
    Postmortem Evidence of Brain Inflammatory Markers and Injury in Septic Patients: A Systematic Review.
    Crit Care Med. 2022;50:e241-e252.
    PubMed     Abstract available


    February 2022
  90. DURAND M, Hagimont E, Louis H, Asfar P, et al
    The beta1-Adrenergic Receptor Contributes to Sepsis-Induced Immunosuppression Through Modulation of Regulatory T-Cell Inhibitory Function.
    Crit Care Med. 2022 Feb 18. pii: 00003246-900000000-94984.
    PubMed     Abstract available


  91. GOMEZ H, Del Rio-Pertuz G, Priyanka P, Manrique-Caballero CL, et al
    Association of Metformin Use During Hospitalization and Mortality in Critically Ill Adults With Type 2 Diabetes Mellitus and Sepsis.
    Crit Care Med. 2022 Feb 7. pii: 00003246-900000000-95003.
    PubMed     Abstract available


  92. DREWRY AM, Mohr NM, Ablordeppey EA, Dalton CM, et al
    Therapeutic Hyperthermia Is Associated With Improved Survival in Afebrile Critically Ill Patients With Sepsis: A Pilot Randomized Trial.
    Crit Care Med. 2022 Feb 7. pii: 00003246-900000000-95002.
    PubMed     Abstract available


    January 2022
  93. INAGAWA T, Ohshimo S, Shime N
    Concerning the Association Between Delayed Administration of Antibiotics and Mortality in Patients With Suspected Sepsis.
    Crit Care Med. 2022;50:e87-e88.
    PubMed    


  94. PARKER MM
    Sepsis Definitions: I Know It When I See It.
    Crit Care Med. 2022;50:148-150.
    PubMed    


  95. YANG Y, Lu X, Xiao Z
    Insights on Blood Product Transfusions on ICU-Acquired Infections in Septic Shock.
    Crit Care Med. 2022;50:e102.
    PubMed    


    December 2021
  96. HONORE PM, Redant S, Preseau T, Kaefer K, et al
    Procalcitonin as a Mediator in Sepsis: Are We Reinventing the Wheel?
    Crit Care Med. 2021;49:e1255-e1256.
    PubMed    


  97. KIMBALL SL, Levy MM
    Sepsis and the Opioid Crisis: Integrating Treatment for Two Public Health Emergencies.
    Crit Care Med. 2021;49:2151-2153.
    PubMed    


  98. BIBAN P, Marlow N, Te Pas AB, Fanaroff AA, et al
    Advances in Neonatal Critical Care: Pushing at the Boundaries and Connecting to Long-Term Outcomes.
    Crit Care Med. 2021;49:2003-2016.
    PubMed    


    November 2021
  99. RHEE C, Klompas M
    Conducting Sepsis Surveillance by Applying Sepsis-3 Criteria to Electronic Health Record Data: Promises and Potential Pitfalls.
    Crit Care Med. 2021;49:1983-1986.
    PubMed    


  100. EVANS L, Rhodes A, Alhazzani W, Antonelli M, et al
    Executive Summary: Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic Shock 2021.
    Crit Care Med. 2021;49:1974-1982.
    PubMed    


  101. MARTIN GS, Kane-Gill SL, Nadkarni V, Sorce LR, et al
    The Evolution of Toolkits and Bundles to Improve the Care of Sepsis Patients.
    Crit Care Med. 2021;49:1849-1850.
    PubMed    


  102. SHAPPELL CN, Klompas M, Ochoa A, Rhee C, et al
    Likelihood of Bacterial Infection in Patients Treated With Broad-Spectrum IV Antibiotics in the Emergency Department.
    Crit Care Med. 2021;49:e1144-e1150.
    PubMed     Abstract available


    October 2021
  103. LEE HY, Lee J, Jung YS, Kwon WY, et al
    Preexisting Clinical Frailty Is Associated With Worse Clinical Outcomes in Patients With Sepsis.
    Crit Care Med. 2021 Oct 6. pii: 00003246-900000000-95052.
    PubMed     Abstract available


  104. MENON K, Schlapbach LJ, Akech S, Argent A, et al
    Criteria for Pediatric Sepsis-A Systematic Review and Meta-Analysis by the Pediatric Sepsis Definition Taskforce.
    Crit Care Med. 2021 Oct 6. pii: 00003246-900000000-95050.
    PubMed     Abstract available


  105. EVANS L, Rhodes A, Alhazzani W, Antonelli M, et al
    Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.
    Crit Care Med. 2021 Oct 4. pii: 00003246-900000000-95059.
    PubMed    


  106. CHOTALIA M, Ali M, Hebballi R, Singh H, et al
    Hyperdynamic Left Ventricular Ejection Fraction in ICU Patients With Sepsis.
    Crit Care Med. 2021 Oct 4. pii: 00003246-900000000-95057.
    PubMed     Abstract available


  107. HAN X, Spicer A, Carey KA, Gilbert ER, et al
    Identifying High-Risk Subphenotypes and Associated Harms From Delayed Antibiotic Orders and Delivery.
    Crit Care Med. 2021;49:1694-1705.
    PubMed     Abstract available


    September 2021
  108. KHOWAJA AR, Willms AJ, Krause C, Carriere S, et al
    The Return on Investment of a Province-Wide Quality Improvement Initiative for Reducing In-Hospital Sepsis Rates and Mortality in British Columbia, Canada.
    Crit Care Med. 2021 Sep 29. pii: 00003246-900000000-95060.
    PubMed     Abstract available


  109. YU X, Chen J, Tang H, Tu Q, et al
    Identifying Prokineticin2 as a Novel Immunomodulatory Factor in Diagnosis and Treatment of Sepsis.
    Crit Care Med. 2021 Sep 27. pii: 00003246-900000000-95065.
    PubMed     Abstract available


  110. FRANK CE, Buchman TG, Simpson SQ, Sciarretta KL, et al
    Sepsis Among Medicare Beneficiaries: 4. Precoronavirus Disease 2019 Update January 2012-February 2020.
    Crit Care Med. 2021 Sep 27. pii: 00003246-900000000-95064.
    PubMed     Abstract available


  111. ASSOULINE B, Faivre A, Verissimo T, Sangla F, et al
    Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis.
    Crit Care Med. 2021 Sep 27. pii: 00003246-900000000-95063.
    PubMed     Abstract available


  112. TAYLOR SP, Murphy S, Rios A, McWilliams A, et al
    Effect of a Multicomponent Sepsis Transition and Recovery Program on Mortality and Readmissions After Sepsis: The Improving Morbidity During Post-Acute Care Transitions for Sepsis Randomized Clinical Trial.
    Crit Care Med. 2021 Sep 16. pii: 00003246-900000000-95096.
    PubMed     Abstract available


  113. SATO R, Hasegawa D, Prasitlumkum N, Ueoka M, et al
    Effect of IV High-Dose Vitamin C on Mortality in Patients With Sepsis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Crit Care Med. 2021 Sep 8. pii: 00003246-900000000-95105.
    PubMed     Abstract available


  114. YASUHARA S, Alston TA, Martyn JAJ
    Freshly Isolated Mitochondria as Therapeutic Agents in Sepsis: Can They Go Home Again?
    Crit Care Med. 2021;49:1584-1587.
    PubMed    


  115. KANTH SM, Torabi-Parizi P
    Personalized Sepsis Treatment: Are We There Yet?
    Crit Care Med. 2021;49:1576-1582.
    PubMed    


  116. GUINAULT D, Nicolau-Travers ML, Silva S, Cointault O, et al
    Expression of Exhaustion Markers on CD8+ T-Cell Patterns Predict Outcomes in Septic Patients Admitted to the ICU.
    Crit Care Med. 2021;49:1513-1523.
    PubMed     Abstract available


    August 2021
  117. TARABICHI Y, Cheng A, Bar-Shain D, McCrate BM, et al
    Improving Timeliness of Antibiotic Administration Using a Provider and Pharmacist Facing Sepsis Early Warning System in the Emergency Department Setting: A Randomized Controlled Quality Improvement Initiative.
    Crit Care Med. 2021 Aug 20. pii: 00003246-900000000-95111.
    PubMed     Abstract available


  118. VALIK JK, Mellhammar L, Sunden-Cullberg J, Ward L, et al
    Peripheral Oxygen Saturation Facilitates Assessment of Respiratory Dysfunction in the Sequential Organ Failure Assessment Score With Implications for the Sepsis-3 Criteria.
    Crit Care Med. 2021 Aug 18. pii: 00003246-900000000-95113.
    PubMed     Abstract available


  119. TAKAYAMA W, Endo A, Morishita K, Otomo Y, et al
    Dielectric Blood Coagulometry for the Early Detection of Sepsis-Induced Disseminated Intravascular Coagulation: A Prospective Observational Study.
    Crit Care Med. 2021 Aug 9. pii: 00003246-900000000-95128.
    PubMed     Abstract available


  120. DELLINGER RP, Levy MM, Schorr CA, Townsend SR, et al
    50 Years of Sepsis Investigation/Enlightenment Among Adults-The Long and Winding Road.
    Crit Care Med. 2021 Aug 4. pii: 00003246-900000000-95133.
    PubMed    


  121. HONORE PM, Redant S, Kaefer K, Barreto Gutierrez L, et al
    Serum Agmatine Levels Were Negatively Correlated With the Severity of Sepsis: Beware of Potential Confounders!
    Crit Care Med. 2021;49:e810-e811.
    PubMed    


  122. PLOPPER GE, Sciarretta KL, Buchman TG
    Disparities in Sepsis Outcomes May Be Attributable to Access to Care.
    Crit Care Med. 2021;49:1358-1360.
    PubMed    


  123. PREST J, Sathananthan M, Jeganathan N
    Current Trends in Sepsis-Related Mortality in the United States.
    Crit Care Med. 2021;49:1276-1284.
    PubMed     Abstract available


  124. SHAH PK, Ginestra JC, Ungar LH, Junker P, et al
    A Simulated Prospective Evaluation of a Deep Learning Model for Real-Time Prediction of Clinical Deterioration Among Ward Patients.
    Crit Care Med. 2021;49:1312-1321.
    PubMed     Abstract available


  125. DESGROUAS M, Merdji H, Bretagnol A, Barin-Le Guellec C, et al
    Kinetic Glomerular Filtration Rate Equations in Patients With Shock: Comparison With the Iohexol-Based Gold-Standard Method.
    Crit Care Med. 2021;49:e761-e770.
    PubMed     Abstract available


    July 2021
  126. VAZQUEZ GUILLAMET MC, Dodda S, Liu L, Kollef MH, et al
    Race Does Not Impact Sepsis Outcomes When Considering Socioeconomic Factors in Multilevel Modeling.
    Crit Care Med. 2021 Jul 13. pii: 00003246-900000000-95151.
    PubMed     Abstract available


  127. SHAPPELL CN, Klompas M, Rhee C
    Quantifying the Burden of Viral Sepsis During the Coronavirus Disease 2019 Pandemic and Beyond.
    Crit Care Med. 2021 Jul 12. pii: 00003246-900000000-95161.
    PubMed    


  128. KARAKIKE E, Giamarellos-Bourboulis EJ, Kyprianou M, Fleischmann-Struzek C, et al
    Coronavirus Disease 2019 as Cause of Viral Sepsis: A Systematic Review and Meta-Analysis.
    Crit Care Med. 2021 Jul 12. pii: 00003246-900000000-95156.
    PubMed     Abstract available



  129. Toward More Rational Time-to-Antibiotic Metrics for Suspected Sepsis: Erratum.
    Crit Care Med. 2021;49:e740.
    PubMed    


  130. HONORE PM, Redant S, Kaefer K, Barreto Gutierrez L, et al
    Higher Levels of S-100beta-a Biomarker of Astrocyte and Glial Activation Were Associated With a Greater Delirium Duration in Sepsis and Traumatic Brain Injury Patients: Beware of Some Confounders!
    Crit Care Med. 2021;49:e736-e737.
    PubMed    


  131. HONORE PM, Redant S, Preseau T, Kaefer K, et al
    Heparin-Binding Protein Performs Better for Detecting Sepsis Among Patients Presenting With Signs of Systemic Infection Compared With Procalcitonin, C-Reactive Protein, and Lactate Level, and Heparin-Binding Protein Is Sufficient for Both Ruling in an
    Crit Care Med. 2021;49:e733-e734.
    PubMed    


  132. STAUNTON O, Staunton C
    We Are Not Waiting for a Cure for Sepsis-We Are Waiting for Leadership.
    Crit Care Med. 2021;49:1192-1193.
    PubMed    


  133. SHAH AD, MacCallum NS, Harris S, Brealey DA, et al
    Descriptors of Sepsis Using the Sepsis-3 Criteria: A Cohort Study in Critical Care Units Within the U.K. National Institute for Health Research Critical Care Health Informatics Collaborative.
    Crit Care Med. 2021 Jul 1. doi: 10.1097/CCM.0000000000005169.
    PubMed     Abstract available


  134. HOLDER AL, Shashikumar SP, Wardi G, Buchman TG, et al
    A Locally Optimized Data-Driven Tool to Predict Sepsis-Associated Vasopressor Use in the ICU.
    Crit Care Med. 2021 Jul 1. doi: 10.1097/CCM.0000000000005175.
    PubMed     Abstract available


  135. CHURPEK MM, Dumanian J, Dussault N, Bhavani SV, et al
    Determining the Electronic Signature of Infection in Electronic Health Record Data.
    Crit Care Med. 2021;49:e673-e682.
    PubMed     Abstract available


  136. YEHYA N, Fazelinia H, Lawrence GG, Spruce LA, et al
    Plasma Nucleosomes Are Associated With Mortality in Pediatric Acute Respiratory Distress Syndrome.
    Crit Care Med. 2021;49:1149-1158.
    PubMed     Abstract available


    June 2021
  137. ALRAWASHDEH M, Klompas M, Kimmel S, Larochelle MR, et al
    Epidemiology, Outcomes, and Trends of Patients With Sepsis and Opioid-Related Hospitalizations in U.S. Hospitals.
    Crit Care Med. 2021 Jun 23. pii: 00003246-900000000-95191.
    PubMed     Abstract available


  138. HONORE PM, Redant S, Kaefer K, Barreto Gutierrez L, et al
    Procalcitonin Is Useful for Antibiotic Deescalation in Sepsis and Septic Shock: Beware of Some Confounders!
    Crit Care Med. 2021;49:e659.
    PubMed    


  139. OXMAN DA
    Less Lumping and More Splitting: Why We Should Not Call COVID Sepsis.
    Crit Care Med. 2021;49:e656-e657.
    PubMed    


  140. PEJU E, Llitjos JF, Charpentier J, Francois A, et al
    Impact of Blood Product Transfusions on the Risk of ICU-Acquired Infections in Septic Shock.
    Crit Care Med. 2021;49:912-922.
    PubMed     Abstract available


    May 2021
  141. DE ROQUETAILLADE C, Mansouri S, Brumpt C, Neuwirth M, et al
    Comparison of Circulating Immune Cells Profiles and Kinetics Between Coronavirus Disease 2019 and Bacterial Sepsis.
    Crit Care Med. 2021 May 18. pii: 00003246-900000000-95220.
    PubMed     Abstract available


  142. GOETZ G, Hawlik K, Wild C
    Extracorporeal Cytokine Adsorption Therapy As a Preventive Measure in Cardiac Surgery and As a Therapeutic Add-On Treatment in Sepsis: An Update Systematic Review of Comparative Efficacy and Safety.
    Crit Care Med. 2021 May 3. pii: 00003246-900000000-95226.
    PubMed     Abstract available


  143. ABRAHAM E
    Moving Forward With Refinement of Definitions for Sepsis.
    Crit Care Med. 2021;49:861-863.
    PubMed    


  144. RHEE C, Heil EL
    Toward More Rational Time-to-Antibiotic Metrics for Suspected Sepsis.
    Crit Care Med. 2021;49:858-860.
    PubMed    


    April 2021
  145. MOLINARI L, Heskia F, Peerapornratana S, Ronco C, et al
    Limiting Acute Kidney Injury Progression In Sepsis: Study Protocol and Trial Simulation.
    Crit Care Med. 2021 Apr 30. pii: 00003246-900000000-95233.
    PubMed     Abstract available


  146. TAN K, Harazim M, Simpson A, Tan YC, et al
    Association Between Premorbid Beta-Blocker Exposure and Sepsis Outcomes-The Beta-Blockers in European and Australian/American Septic Patients (BEAST) Study.
    Crit Care Med. 2021 Apr 28. doi: 10.1097/CCM.0000000000005034.
    PubMed     Abstract available


  147. DE CARVALHO LRP, Abreu SC, de Castro LL, Andrade da Silva LH, et al
    Mitochondria-Rich Fraction Isolated From Mesenchymal Stromal Cells Reduces Lung and Distal Organ Injury in Experimental Sepsis.
    Crit Care Med. 2021 Apr 19. pii: 00003246-900000000-95254.
    PubMed     Abstract available


  148. OH TK, Park HY, Song IA
    Depression and Long-Term Survival Among South Korean Sepsis Survivors: A Nationwide Cohort Study From 2011 to 2014.
    Crit Care Med. 2021 Apr 8. pii: 00003246-900000000-95275.
    PubMed     Abstract available


  149. LAT I, Coopersmith CM, De Backer D
    The Surviving Sepsis Campaign: Fluid Resuscitation and Vasopressor Therapy Research Priorities in Adult Patients.
    Crit Care Med. 2021;49:623-635.
    PubMed     Abstract available


  150. CARR AC
    Is "Mega-Dose" IV Vitamin C Required for Septic and Critical Coronavirus Disease 2019 Patients?
    Crit Care Med. 2021;49:e477-e478.
    PubMed    


  151. JORRES A
    Initial Arterial Blood Pressure Targets in Patients With Septic Shock: One Size Fits All or Made to Measure?
    Crit Care Med. 2021;49:719-721.
    PubMed    


  152. DEMISELLE J, Seegers V, Lemerle M, Meziani F, et al
    Prior Exposure to Angiotensin II Receptor Blockers in Patients With Septic Shock to Individualize Mean Arterial Pressure Target? A Post Hoc Analysis of the Sepsis and Mean Arterial Pressure (SEPSISPAM) Trial.
    Crit Care Med. 2021;49:e412-e422.
    PubMed     Abstract available


  153. HARIRI G, Urbina T, Lavillegrand JR, Gasperment M, et al
    Exaggerated Microvascular Vasodilating Responses in Cirrhotic Patients With Septic Shock.
    Crit Care Med. 2021;49:e404-e411.
    PubMed     Abstract available


    March 2021
  154. REN X
    Potential Endotype Transition for Coronavirus Disease 2019-Related Sepsis With Longitudinal Transcriptome Profiling.
    Crit Care Med. 2021 Mar 16. pii: 00003246-900000000-95304.
    PubMed    


  155. JONES TW, Azimi H, Scott C, Newsome AS, et al
    Does Norepinephrine Exhibit a Time-Dose Relationship in Septic Shock?
    Crit Care Med. 2021;49:e345-e346.
    PubMed    


    February 2021
  156. BORN S, Dame C, Matthaus-Kramer C, Schlapbach LJ, et al
    Epidemiology of Sepsis Among Children and Neonates in Germany: Results From an Observational Study Based on Nationwide Diagnosis-Related Groups Data Between 2010 and 2016.
    Crit Care Med. 2021 Feb 23. doi: 10.1097/CCM.0000000000004919.
    PubMed     Abstract available


  157. WANG HE, Kabeto MM, Gray M, Wadley VG, et al
    Trajectory of Cognitive Decline After Sepsis.
    Crit Care Med. 2021 Feb 18. doi: 10.1097/CCM.0000000000004897.
    PubMed     Abstract available


  158. TAYLOR SP, Anderson WE, Beam K, Taylor B, et al
    The Association Between Antibiotic Delay Intervals and Hospital Mortality Among Patients Treated in the Emergency Department for Suspected Sepsis.
    Crit Care Med. 2021 Feb 15. pii: 00003246-900000000-95342.
    PubMed     Abstract available


  159. DEMERLE KM, Angus DC, Baillie JK, Brant E, et al
    Sepsis Subclasses: A Framework for Development and Interpretation.
    Crit Care Med. 2021 Feb 15. pii: 00003246-900000000-95341.
    PubMed     Abstract available


  160. YU SC, Betthauser KD, Gupta A, Lyons PG, et al
    Comparison of Sepsis Definitions as Automated Criteria.
    Crit Care Med. 2021 Feb 12. pii: 00003246-900000000-95354.
    PubMed     Abstract available


  161. COOPERSMITH CM, Antonelli M, Bauer SR, Deutschman CS, et al
    Surviving Sepsis Campaign: Research Priorities for Coronavirus Disease 2019 in Critical Illness.
    Crit Care Med. 2021 Feb 12. pii: 00003246-900000000-95348.
    PubMed     Abstract available


  162. BEESLEY SJ, Sorensen J, Walkey AJ, Tonna JE, et al
    Long-Term Implications of Abnormal Left Ventricular Strain During Sepsis.
    Crit Care Med. 2021 Feb 12. pii: 00003246-900000000-95347.
    PubMed     Abstract available


  163. JACQUEMET PL, Schweizer R, Ruste M, Pozzi M, et al
    Venoarterial Extracorporeal Membranous Oxygenation Should Be Considered as an Appropriate Rescue Therapy for Sepsis-Induced Refractory Cardiogenic Shock.
    Crit Care Med. 2021;49:e210-e211.
    PubMed    


  164. MUNROE E, Prescott HC
    Late Mortality From Sepsis: What We Know and What It Means.
    Crit Care Med. 2021;49:353-355.
    PubMed    


  165. ROURKE EM, Kuttab HI, Lykins JD, Hughes MD, et al
    Fluid Resuscitation in Septic Patients With Comorbid Heart Failure.
    Crit Care Med. 2021;49:e201-e204.
    PubMed    


  166. TRIPATHI S, Kumar S, Kaushik S
    The Practice and Complications of Midline Catheters: A Systematic Review.
    Crit Care Med. 2021;49:e140-e150.
    PubMed     Abstract available


    January 2021
  167. ALHAZZANI W, Evans L, Alshamsi F, Moller MH, et al
    Surviving Sepsis Campaign Guidelines on the Management of Adults With Coronavirus Disease 2019 (COVID-19) in the ICU: First Update.
    Crit Care Med. 2021 Jan 28. doi: 10.1097/CCM.0000000000004899.
    PubMed     Abstract available


  168. KELLUM JA, Artigas A, Gunnerson KJ, Honore PM, et al
    Use of Biomarkers to Identify Acute Kidney Injury to Help Detect Sepsis in Patients With Infection.
    Crit Care Med. 2021 Jan 20. doi: 10.1097/CCM.0000000000004845.
    PubMed     Abstract available


  169. LIZZA BD, Betthauser KD, Juang PH, Hampton NB, et al
    Racial Disparities in Readmissions Following Initial Hospitalization for Sepsis.
    Crit Care Med. 2021 Jan 20. doi: 10.1097/CCM.0000000000004809.
    PubMed     Abstract available


  170. BONAZZETTI C, Morena V, Giacomelli A, Oreni L, et al
    Unexpectedly High Frequency of Enterococcal Bloodstream Infections in Coronavirus Disease 2019 Patients Admitted to an Italian ICU: An Observational Study.
    Crit Care Med. 2021;49:e31-e40.
    PubMed     Abstract available


  171. HANSON SJ, Patel N, Petersen TL, Feng M, et al
    The authors reply.
    Crit Care Med. 2021;49:e111-e112.
    PubMed    


  172. ARCOVERDE DE SOUSA D, Spessoto AB
    Peripherally Inserted Central Catheter Versus Central Venous Catheter: It Is Time to Use Different Approaches and Metrics for a More Useful Comparison.
    Crit Care Med. 2021;49:e109-e110.
    PubMed    


  173. BARANOWSKY A, Appelt J, Kleber C, Lange T, et al
    Procalcitonin Exerts a Mediator Role in Septic Shock Through the Calcitonin Gene-Related Peptide Receptor.
    Crit Care Med. 2021;49:e41-e52.
    PubMed     Abstract available


  174. VERBOOM DM, van de Groep K, Boel CHE, Haas PJA, et al
    The Diagnostic Yield of Routine Admission Blood Cultures in Critically Ill Patients.
    Crit Care Med. 2021;49:60-69.
    PubMed     Abstract available


  175. WONG HR, Hart KW, Lindsell CJ, Sweeney TE, et al
    External Corroboration That Corticosteroids May Be Harmful to Septic Shock Endotype A Patients.
    Crit Care Med. 2021;49:e98-e101.
    PubMed     Abstract available


  176. SEVRANSKY JE, Agarwal A, Jabaley CS, Rochwerg B, et al
    Standardized Care Is Better Than Individualized Care for the Majority of Critically Ill Patients.
    Crit Care Med. 2021;49:151-155.
    PubMed    


    December 2020
  177. FARRAH K, McIntyre L, Doig CJ, Talarico R, et al
    Sepsis-Associated Mortality, Resource Use, and Healthcare Costs: A Propensity-Matched Cohort Study.
    Crit Care Med. 2020 Dec 17. doi: 10.1097/CCM.0000000000004777.
    PubMed     Abstract available


  178. PLATA-MENCHACA EP, Ferrer R
    Procalcitonin Is Useful for Antibiotic Deescalation in Sepsis.
    Crit Care Med. 2020 Dec 8. doi: 10.1097/CCM.0000000000004776.
    PubMed    


  179. ROWE S, Alcheikh A
    Harm or Benefit of High-Dose Vitamin C in Adult Patients With Sepsis and Glucose-6-Phosphate Dehydrogenase Deficiency?
    Crit Care Med. 2020;48:e1356.
    PubMed    


  180. KADRI SS
    The Sepsis Proxy Pageant: Seeking Beauty in Imperfection.
    Crit Care Med. 2020;48:1917-1919.
    PubMed    


    November 2020
  181. LANKADEVA YR, Peiris RM, Okazaki N, Birchall IE, et al
    Reversal of the Pathophysiological Responses to Gram-Negative Sepsis by Megadose Vitamin C.
    Crit Care Med. 2020 Nov 25. doi: 10.1097/CCM.0000000000004770.
    PubMed     Abstract available


  182. SWEENEY TE, Liesenfeld O, Wacker J, He YD, et al
    Validation of Inflammopathic, Adaptive, and Coagulopathic Sepsis Endotypes in Coronavirus Disease 2019.
    Crit Care Med. 2020 Nov 17. doi: 10.1097/CCM.0000000000004786.
    PubMed     Abstract available


  183. WU YL, Yo CH, Hsu WT, Qian F, et al
    Accuracy of Heparin-Binding Protein in Diagnosing Sepsis: A Systematic Review and Meta-Analysis.
    Crit Care Med. 2020 Nov 16. doi: 10.1097/CCM.0000000000004738.
    PubMed     Abstract available


  184. BANIASADI A, Rezaeirad S, Zare H, Ghassemi MM, et al
    Two-Step Imputation and AdaBoost-Based Classification for Early Prediction of Sepsis on Imbalanced Clinical Data.
    Crit Care Med. 2020 Nov 5. doi: 10.1097/CCM.0000000000004705.
    PubMed     Abstract available


    October 2020
  185. NESARAGI N, Patidar S
    Early Prediction of Sepsis From Clinical Data Using Ratio and Power-Based Features.
    Crit Care Med. 2020 Oct 13. doi: 10.1097/CCM.0000000000004691.
    PubMed     Abstract available


  186. HE Z, Du L, Zhang P, Zhao R, et al
    Early Sepsis Prediction Using Ensemble Learning With Deep Features and Artificial Features Extracted From Clinical Electronic Health Records.
    Crit Care Med. 2020 Oct 12. doi: 10.1097/CCM.0000000000004644.
    PubMed     Abstract available


  187. KEMPKER JA, Rudd KE, Wang HE, Martin GS, et al
    Sepsis Epidemiology Across the International Classification of Diseases, 9th Edition, to International Classification of Diseases, 10th Edition, Chasm-A Direct Application of the Institute for Health Metrics and Evaluation Case Definition to Hospital
    Crit Care Med. 2020 Oct 2. doi: 10.1097/CCM.0000000000004577.
    PubMed     Abstract available


    April 2020
  188. MATSUDA W
    Should We Restrict ICU Admission for Frail Septic Patients?
    Crit Care Med. 2020;48:e342-e343.
    PubMed    


  189. CARLTON EF, Prescott HC
    The authors reply.
    Crit Care Med. 2020;48:e334-e335.
    PubMed    


  190. PATEL S, Katanga JA, Burman S, Said H, et al
    Making Sense of Readmissions.
    Crit Care Med. 2020;48:e333-e334.
    PubMed    


  191. SWEENEY DA, Kalil AC
    Be Quick But Don't Hurry: Septic Shock, Staphylococcus aureus Bacteremia, and the Timing of Appropriate Antibiotics.
    Crit Care Med. 2020;48:608-609.
    PubMed    


  192. SILVA AYO, Amorim EA, Barbosa-Silva MC, Lima MN, et al
    Mesenchymal Stromal Cells Protect the Blood-Brain Barrier, Reduce Astrogliosis, and Prevent Cognitive and Behavioral Alterations in Surviving Septic Mice.
    Crit Care Med. 2020;48:e290-e298.
    PubMed     Abstract available


  193. CORL KA, Zeba F, Caffrey AR, Hermenau M, et al
    Delay in Antibiotic Administration Is Associated With Mortality Among Septic Shock Patients With Staphylococcus aureus Bacteremia.
    Crit Care Med. 2020;48:525-532.
    PubMed     Abstract available


  194. LACHMANN G, Knaak C, Vorderwulbecke G, La Rosee P, et al
    Hyperferritinemia in Critically Ill Patients.
    Crit Care Med. 2020;48:459-465.
    PubMed     Abstract available


    March 2020
  195. KUTTAB HI, Ward MA
    The authors reply.
    Crit Care Med. 2020;48:e260-e261.
    PubMed    


  196. JONES TW, Finder S, Newsome AS, Smith SE, et al
    Getting to the Heart of the Matter: What We Know About Fluid Resuscitation in Septic Heart Failure Patients.
    Crit Care Med. 2020;48:e259-e260.
    PubMed    


  197. LAW AC, Stevens JP, Walkey AJ
    The authors reply.
    Crit Care Med. 2020;48:e249-e250.
    PubMed    


  198. OUD L
    Trends of Time to Hospital Mortality Versus Timing of Death Among Patients With Septic Shock in Administrative Data.
    Crit Care Med. 2020;48:e249.
    PubMed    


  199. MARRARO GA, Spada C, Zeng Y
    Administrative Database and Empiric Therapy Are Always Useful for Appropriate Treatment of Pediatric Patients?
    Crit Care Med. 2020;48:438-440.
    PubMed    


  200. JILANI SM, Giroir BP
    Septic Shock in Children: When Should Prevention Start and Treatment End?
    Crit Care Med. 2020;48:426-428.
    PubMed    


  201. ZADOR Z, Landry A, Balas M, Marshall JC, et al
    Data Driven Analysis Reveals Shared Transcriptome Response, Immune Cell Composition, and Distinct Mortality Rates Across Differing Etiologies of Critical Illness.
    Crit Care Med. 2020;48:338-343.
    PubMed     Abstract available


  202. ZIMMERMAN JJ, Banks R, Berg RA, Zuppa A, et al
    Trajectory of Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock.
    Crit Care Med. 2020;48:329-337.
    PubMed     Abstract available


  203. ZIMMERMAN JJ, Banks R, Berg RA, Zuppa A, et al
    Critical Illness Factors Associated With Long-Term Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock.
    Crit Care Med. 2020;48:319-328.
    PubMed     Abstract available


  204. BELLETTI A, Nagy A, Sartorelli M, Mucchetti M, et al
    Effect of Continuous Epinephrine Infusion on Survival in Critically Ill Patients: A Meta-Analysis of Randomized Trials.
    Crit Care Med. 2020;48:398-405.
    PubMed     Abstract available


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