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Sepsis

Free Subscription Articles published in Crit Care Med Retrieve available abstracts of 135 articles: HTML format

Single Articles

November 2025
1. NAZER L, Kalil AC
   What Impacts Sepsis Outcomes in Low- and Middle-Income Countries: Antibiotic Timing, Presence of Shock, or Supportive Care?
   Crit Care Med. 2025 Nov 21. doi: 10.1097/CCM.0000000000006973.
   PubMed    
   
   
   
2. FLICK RJ, Kamphuis LA, Valley TS, Armstrong-Hough M, et al
   Association of Sepsis Survivor Subtypes With Long-Term Mortality and Disability After Discharge: A Retrospective Cohort Study.
   Crit Care Med. 2025 Nov 13. doi: 10.1097/CCM.0000000000006933.
   PubMed     Abstract available
   
   
   
3. COSTON TD, Wright SW, Hantrakun V, Rudd KE, et al
   Pre-referral Antibiotics and Mortality Among Adults With Sepsis in Southeast Asia: A Secondary Analysis of a Prospective Cohort Study.
   Crit Care Med. 2025 Nov 6. doi: 10.1097/CCM.0000000000006932.
   PubMed     Abstract available
   
   
   
4. CHEN SC
   Reevaluating Mega-Dose Esomeprazole in Sepsis: Implications of Comparator Exposure and Comorbidity Imbalance.
   Crit Care Med. 2025;53:e2372-e2373.
   PubMed    
   
   
   
5. MOURY J, Gennart T, Oueslati I, De Lissnyder N, et al
   Initial Fluid Resuscitation With Lactated Ringer's Versus Normal Saline in Sepsis: Uncertain Evidence for a Survival Benefit.
   Crit Care Med. 2025;53:e2369-e2370.
   PubMed    
   
   
   
6. SANCHEZ E C, Taha A, Tolba Y, Hernandez G, et al
   Assessment of Tissue Perfusion Pressure in Patients With Septic Shock: Beyond Mean Arterial Pressure.
   Crit Care Med. 2025;53:e2305-e2317.
   PubMed     Abstract available
   
   
   October 2025
7. WEINGART MF, Willmore A, Zhuo H, Magee L, et al
   Prognostic Relevance of Inflammatory Subphenotypes in Immunocompromised Patients With Sepsis.
   Crit Care Med. 2025 Oct 28. doi: 10.1097/CCM.0000000000006920.
   PubMed     Abstract available
   
   
   
8. SIM JOHNSTON MW, Lorimer AJ, Haines KJ, Litton E, et al
   Experiencing Sepsis: A Meta-Ethnography.
   Crit Care Med. 2025 Oct 22. doi: 10.1097/CCM.0000000000006913.
   PubMed     Abstract available
   
   
   
9. SONG MJ, Seo WI, Jang Y, Park S, et al
   RBC Transfusion Practices in Critically Ill Patients With Sepsis.
   Crit Care Med. 2025 Oct 15. doi: 10.1097/CCM.0000000000006892.
   PubMed     Abstract available
   
   
   
10. LEE KE, Lee J, Lee SM, Oh DK, et al
    Hyperosmolar Dehydration in Sepsis: Implications for Initial Fluid Management.
    Crit Care Med. 2025 Oct 8. doi: 10.1097/CCM.0000000000006891.
    PubMed     Abstract available
    
    
    
11. PATEL JJ, Jasti J, Hu K
    Lactated Ringer's or Normal Saline for Initial Fluid Resuscitation in Sepsis-Induced Hypotension.
    Crit Care Med. 2025;53:e2120-e2121.
    PubMed    
    
    
    
12. CHEN SC, Chen CC
    Enhancing Sepsis Outcomes: Prioritizing Local Over Regional Solutions.
    Crit Care Med. 2025;53:e2112-e2113.
    PubMed    
    
    
    
13. TAKAHASHI N, Campbell KR, Nakada TA, Walley KR, et al
    Decreased Clearance of Low-Density Lipoprotein Cholesterol is Causally Associated With Increased Mortality of Septic Shock.
    Crit Care Med. 2025;53:e2033-e2042.
    PubMed     Abstract available
    
    
    September 2025
14. AOKI Y, Shimizu M, Nakajima M, Ota K, et al
    Association Between Activation of a Rapid Response Team and Outcomes of Sepsis in General Wards: A Nationwide Observational Study Using the Japanese Intensive Care Patient Database.
    Crit Care Med. 2025 Sep 12. doi: 10.1097/CCM.0000000000006857.
    PubMed     Abstract available
    
    
    
15. ZOU LJ, Ruan H
    The Impact of Obesity on Sepsis Mediated by Omega-3 Status.
    Crit Care Med. 2025;53:e1865-e1866.
    PubMed    
    
    
    August 2025
16. WANG J, Tong Z, Wang X, Wang G, et al
    Time Course of Morbidity and Mortality Across Echocardiographic Phenotypes in Patients With Sepsis: A Systematic Review and Meta-Analysis.
    Crit Care Med. 2025 Aug 25. doi: 10.1097/CCM.0000000000006844.
    PubMed     Abstract available
    
    
    
17. CAMPBELL KR, Takahashi N, Shimada T, Nakada TA, et al
    Obesity- and Lipid-Related Traits May Causally Contribute to Sepsis-Associated Acute Kidney Injury.
    Crit Care Med. 2025 Aug 14. doi: 10.1097/CCM.0000000000006812.
    PubMed     Abstract available
    
    
    
18. PONTES AZEVEDO LC
    Surviving Sepsis: Don't Break the Chain.
    Crit Care Med. 2025 Aug 12. doi: 10.1097/CCM.0000000000006832.
    PubMed    
    
    
    
19. FOX-ROBICHAUD AE
    Supplemental Prevention of Sepsis?
    Crit Care Med. 2025 Aug 6. doi: 10.1097/CCM.0000000000006823.
    PubMed    
    
    
    
20. BOUSQUET G, Parzy G, Barrau D, Gragueb-Chatti I, et al
    Effects of Sevoflurane Inhalation on Pulmonary Hemodynamics in Moderate to Severe Acute Respiratory Distress Syndrome Patients With Septic Shock: A Prospective Cohort Study.
    Crit Care Med. 2025;53:e1659-e1665.
    PubMed     Abstract available
    
    
    
21. SHAH S, Kaul A, Shiwarkar G, Nare R, et al
    Fifth Centile Versus 50th Centile Mean Blood Pressure Targets in Pediatric Septic Shock: A Randomized Controlled Trial.
    Crit Care Med. 2025;53:e1581-e1589.
    PubMed     Abstract available
    
    
    
22. PATANWALA AE, Erstad BL
    Epidemiology of Septic Shock Associated Acute Kidney Injury: A National Retrospective Cohort Study.
    Crit Care Med. 2025;53:e1601-e1609.
    PubMed     Abstract available
    
    
    July 2025
23. ASHANA DC, Parker WF
    Consideration of Sociodemographics in Sepsis Risk Prediction: Implications and Next Steps.
    Crit Care Med. 2025 Jul 17. doi: 10.1097/CCM.0000000000006777.
    PubMed    
    
    
    
24. HIDALGO JL, Kumar VK, Akech SO, Myatra SN, et al
    The Sepsis Chain of Survival: A Comprehensive Framework for Improving Sepsis Outcomes.
    Crit Care Med. 2025 Jul 16. doi: 10.1097/CCM.0000000000006796.
    PubMed     Abstract available
    
    
    
25. WARD MA, Kuttab HI, Badgett RG
    The Effect of Early Fluid Resuscitation on Mortality in Sepsis: A Systematic Review and Meta-Analysis.
    Crit Care Med. 2025 Jul 10. doi: 10.1097/CCM.0000000000006769.
    PubMed     Abstract available
    
    
    
26. RONNER L, Giannini HM, Miano TA, Ittner CAG, et al
    Parsimonious Subphenotyping Algorithms Perform Differently in Patients With Sepsis and Hematologic Malignancy.
    Crit Care Med. 2025 Jul 10. doi: 10.1097/CCM.0000000000006774.
    PubMed     Abstract available
    
    
    
27. NADEL S, Inwald D
    How Low Should We Go?-Blood Pressure Targets in Pediatric Sepsis.
    Crit Care Med. 2025 Jul 2. doi: 10.1097/CCM.0000000000006751.
    PubMed    
    
    
    
28. NAM H, Cha JH, Choi KH, Chung CR, et al
    Association Between Initial Left Ventricular Systolic Dysfunction and Clinical Outcome in Sepsis: A Multicenter Cohort Study.
    Crit Care Med. 2025 Jul 2. doi: 10.1097/CCM.0000000000006771.
    PubMed     Abstract available
    
    
    
29. HE J, Liu Y
    Protective Effect of Omega-3 in Sepsis.
    Crit Care Med. 2025;53:e1526.
    PubMed    
    
    
    June 2025
30. MANSOUR M, Mancebo JG, Dezfulian C
    Shock and Awe: Hemodynamics Scratch the Surface of Surviving In-Hospital Cardiac Arrest Following Pediatric Sepsis.
    Crit Care Med. 2025 Jun 26. doi: 10.1097/CCM.0000000000006754.
    PubMed    
    
    
    
31. MORGAN RW, Reeder RW, Carcillo JA, Carpenter TC, et al
    Outcomes, Characteristics, and Physiology of In-Hospital Cardiac Arrest in Children With Sepsis.
    Crit Care Med. 2025 Jun 25. doi: 10.1097/CCM.0000000000006739.
    PubMed     Abstract available
    
    
    
32. XU S, Kong X, Shi J, Tang Y, et al
    Habitual Glucosamine Use and Risk of Sepsis: A 16-Year Follow-Up Study.
    Crit Care Med. 2025 Jun 12. doi: 10.1097/CCM.0000000000006742.
    PubMed     Abstract available
    
    
    
33. HAUSCHILDT KE, Pan A, Bernstein T, Admon AJ, et al
    Consideration of Sociodemographics in Machine Learning-Driven Sepsis Risk Prediction.
    Crit Care Med. 2025 Jun 9. doi: 10.1097/CCM.0000000000006741.
    PubMed     Abstract available
    
    
    May 2025
34. MONTI G, Carta S, Kotani Y, Bruni A, et al
    A Multinational Randomized Trial of Mega-Dose Esomeprazole As Anti-Inflammatory Agent in Sepsis.
    Crit Care Med. 2025 May 29. doi: 10.1097/CCM.0000000000006720.
    PubMed     Abstract available
    
    
    
35. WALLACE DJ
    Algorithmic Centralization of Sepsis Care Is Not a Promising Public Health Strategy.
    Crit Care Med. 2025 May 9. doi: 10.1097/CCM.0000000000006697.
    PubMed    
    
    
    
36. MCCHESNEY C, Orozco N, Fiorini K, Wong MYS, et al
    Impact of Short-Acting Beta-Blockers on the Outcomes of Patients With Septic Shock: A Systematic Review and Meta-Analysis.
    Crit Care Med. 2025;53:e1125-e1139.
    PubMed     Abstract available
    
    
    April 2025
37. MOHR NM, Tang Y, Gaieski DF, Buckler DG, et al
    Geographic Clusters in Sepsis Hospital Mortality and the Role of Targeted Regionalization.
    Crit Care Med. 2025 Apr 24. doi: 10.1097/CCM.0000000000006678.
    PubMed     Abstract available
    
    
    
38. SIVAPALAN P, Kaas-Hansen BS, Meyhoff TS, Hjortrup PB, et al
    Effects of IV Fluid Restriction According to Standard Fluid Treatment Intensity Across Conservative Versus Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care (CLASSIC) Trial Sites.
    Crit Care Med. 2025 Apr 24. doi: 10.1097/CCM.0000000000006679.
    PubMed     Abstract available
    
    
    
39. LI R, Li B, Dong M, Chen H, et al
    Discharge Is Not the End: Exploring Recovery Strategies and Needs of Pediatric Sepsis Survivors.
    Crit Care Med. 2025;53:e1031-e1032.
    PubMed    
    
    
    
40. WU Y, Xu W
    Enhancing Understanding of the Impact of IV Fluid Volume on Sepsis Mortality.
    Crit Care Med. 2025;53:e1025-e1026.
    PubMed    
    
    
    
41. DARGENT A, Bourredjem A, Jacquier M, Bohe J, et al
    Dexmedetomidine to Reduce Vasopressor Resistance in Refractory Septic Shock: alpha2 Agonist Dexmedetomidine for REfractory Septic Shock (ADRESS): A Double-Blind Randomized Controlled Pilot Trial.
    Crit Care Med. 2025;53:e884-e896.
    PubMed     Abstract available
    
    
    March 2025
42. GIAMARELLOS-BOURBOULIS EJ
    Omega-3 Polyunsaturated Fatty Acids in Sepsis: From Prevention to Early Treatment.
    Crit Care Med. 2025 Mar 3. doi: 10.1097/CCM.0000000000006626.
    PubMed    
    
    
    
43. SHIRAISHI T, Hosokawa K
    We Need a Clinically Relevant Sepsis Screening Tool.
    Crit Care Med. 2025;53:e755-e756.
    PubMed    
    
    
    
44. ELEUTERI D, Montini L, Grieco DL
    A Word of Caution on the Danger of Noninvasive Respiratory Support During Sepsis.
    Crit Care Med. 2025;53:e751-e752.
    PubMed    
    
    
    February 2025
45. LIU K, Nakashima T, Goto T, Nakamura K, et al
    Phenotypes of Functional Decline or Recovery in Sepsis ICU Survivors: Insights From a 1-Year Follow-Up Multicenter Cohort Analysis.
    Crit Care Med. 2025 Feb 24. doi: 10.1097/CCM.0000000000006621.
    PubMed     Abstract available
    
    
    
46. GELBENEGGER G, Shapiro NI, Zeitlinger M, Jilma B, et al
    Lactated Ringer's or Normal Saline for Initial Fluid Resuscitation in Sepsis-Induced Hypotension.
    Crit Care Med. 2025 Feb 19. doi: 10.1097/CCM.0000000000006601.
    PubMed     Abstract available
    
    
    
47. PELTAN ID, Rahmati K, Bledsoe JR, Yoneoka Y, et al
    Performance Evaluation of Prehospital Sepsis Prediction Models.
    Crit Care Med. 2025 Feb 12. doi: 10.1097/CCM.0000000000006586.
    PubMed     Abstract available
    
    
    
48. CUMMINGS MJ, Lutwama JJ, Owor N, Tomoiaga AS, et al
    Host Response Stratification in Malarial and Non-malarial Sepsis: A Prospective, Multicenter Analysis From Uganda.
    Crit Care Med. 2025 Feb 12. doi: 10.1097/CCM.0000000000006591.
    PubMed     Abstract available
    
    
    
49. NARAYAN D, Vlasschaert C, Day AG, Norman P, et al
    Association of Omega-3 Status With Long-Term Risk of Hospitalization for Sepsis.
    Crit Care Med. 2025 Feb 3. doi: 10.1097/CCM.0000000000006593.
    PubMed     Abstract available
    
    
    
50. ROBERT A, Perriens E, Blackman S, Honore PM, et al
    In Sepsis, Procalcitonin-Guided Antibiotic Discontinuation Strategies May Be Beneficial and Safe: Beware of Potential Confounders.
    Crit Care Med. 2025;53:e523-e524.
    PubMed    
    
    
    
51. HUANG L, Shan D
    Refining Outcome Interpretations in Pediatric Sepsis: Mortality, Fluid Management, and Renal Recovery.
    Crit Care Med. 2025;53:e515-e516.
    PubMed    
    
    
    
52. ALMEIDA TML, Freitas FGR, Figueiredo RC, Houly SG, et al
    Acetylsalicylic Acid Treatment in Patients With Sepsis and Septic Shock: A Phase 2, Placebo-Controlled, Randomized Clinical Trial.
    Crit Care Med. 2025;53:e269-e281.
    PubMed     Abstract available
    
    
    January 2025
53. FAN Y, Zhao C, Fan S
    Bridging the Rural-Urban Healthcare Gap: A Multidisciplinary Approach Leveraging Artificial Intelligence and Sociological Analysis in Sepsis Survivorship.
    Crit Care Med. 2025;53:e254-e255.
    PubMed    
    
    
    
54. SHAH FA, Talisa VB, Chang CH, Triantafyllou S, et al
    Heterogeneity in the Effect of Early Goal-Directed Therapy for Septic Shock: A Secondary Analysis of Two Multicenter International Trials.
    Crit Care Med. 2025;53:e4-e14.
    PubMed     Abstract available
    
    
    December 2024
55. ZIMMERMANN T, Brealey D, Singer M
    The Search for Sepsis Biomarkers: A Tale of Promises, Pitfalls, and Potential.
    Crit Care Med. 2024 Dec 18. doi: 10.1097/CCM.0000000000006560.
    PubMed    
    
    
    
56. ANDERSON-SHAW LK
    Assessment of Racial, Ethnic, and Sex-Based Disparities in Time-to-Antibiotics and Sepsis Outcomes in a Large Multihospital Cohort.
    Crit Care Med. 2024;52:1985-1986.
    PubMed    
    
    
    
57. GUPTA S, Rhee C
    Improving Administrative Code-Based Algorithms for Sepsis Surveillance.
    Crit Care Med. 2024;52:1967-1970.
    PubMed    
    
    
    
58. GARLAND A, Li N, Sligl W, Lane A, et al
    Adjudication of Codes for Identifying Sepsis in Hospital Administrative Data by Expert Consensus.
    Crit Care Med. 2024;52:1845-1855.
    PubMed     Abstract available
    
    
    November 2024
59. LIUFU R, Chen Y, Wang JY, Wang YY, et al
    ABO Blood Group and Risk Associated With Sepsis-Associated Thrombocytopenia: A Single-Center Retrospective Study.
    Crit Care Med. 2024 Nov 15. doi: 10.1097/CCM.0000000000006523.
    PubMed     Abstract available
    
    
    
60. KRANIDIOTI E, Ricano-Ponce I, Antonakos N, Kyriazopoulou E, et al
    Modulation of Metabolomic Profile in Sepsis According to the State of Immune Activation.
    Crit Care Med. 2024;52:e536-e544.
    PubMed     Abstract available
    
    
    
61. SCRUTH EA, Liu VX
    The Geographic Puzzle of Sepsis Recovery: Patterns in U.S. Rural and Urban Sepsis Survivors.
    Crit Care Med. 2024;52:1804-1806.
    PubMed    
    
    
    
62. PROUT A
    Are We Out of the Woods Yet? Children Continue to Have Significant Medical Needs After "Recovery" From Sepsis.
    Crit Care Med. 2024;52:1799-1801.
    PubMed    
    
    
    
63. FITZGERALD JC, Weiss SL
    "Rocking" Continuous Renal Replacement Therapy Management in Children and Young Adults With Sepsis: Impact of Hemodynamic Support on Outcomes.
    Crit Care Med. 2024;52:1796-1799.
    PubMed    
    
    
    
64. ROCKENSCHAUB P, Hilbert A, Kossen T, Elbers P, et al
    The Impact of Multi-Institution Datasets on the Generalizability of Machine Learning Prediction Models in the ICU.
    Crit Care Med. 2024;52:1710-1721.
    PubMed     Abstract available
    
    
    October 2024
65. LING RR, Somani J, Ramanathan K
    Biomarker-Guided Antibiotic Discontinuation in Adults Critically Ill With Sepsis: Harnessing Network Meta-Analysis to Guide Clinical Therapy.
    Crit Care Med. 2024;52:1658-1660.
    PubMed    
    
    
    
66. HUANG D, Chen JT
    Early Choices, Lasting Impact: The Colloid Versus Crystalloid Decision in Early Sepsis.
    Crit Care Med. 2024;52:1646-1648.
    PubMed    
    
    
    September 2024
67. CARLTON EF, Rahman M, Maddux AB, Weiss SL, et al
    Frequency of and Risk Factors for Increased Healthcare Utilization After Pediatric Sepsis Hospitalization.
    Crit Care Med. 2024 Sep 19. doi: 10.1097/CCM.0000000000006406.
    PubMed     Abstract available
    
    
    
68. PAK TR, Sanchez SM, McKenna CS, Rhee C, et al
    Assessment of Racial, Ethnic, and Sex-Based Disparities in Time-to-Antibiotics and Sepsis Outcomes in a Large Multihospital Cohort.
    Crit Care Med. 2024 Sep 16. doi: 10.1097/CCM.0000000000006428.
    PubMed     Abstract available
    
    
    
69. STANSKI NL, Gist KM, Hasson D, Stenson EK, et al
    Characteristics and Outcomes of Children and Young Adults With Sepsis Requiring Continuous Renal Replacement Therapy: A Comparative Analysis From the Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease (WE-ROCK).
    Crit Care Med. 2024 Sep 11. doi: 10.1097/CCM.0000000000006405.
    PubMed     Abstract available
    
    
    August 2024
70. CORL KA, Levy MM, Holder AL, Douglas IS, et al
    Moderate IV Fluid Resuscitation Is Associated With Decreased Sepsis Mortality.
    Crit Care Med. 2024 Aug 23. doi: 10.1097/CCM.0000000000006394.
    PubMed     Abstract available
    
    
    
71. KRANIDIOTI E, Ricano-Ponce I, Antonakos N, Kyriazopoulou E, et al
    Modulation of Metabolomic Profile in Sepsis According to the State of Immune Activation.
    Crit Care Med. 2024 Aug 23. doi: 10.1097/CCM.0000000000006391.
    PubMed     Abstract available
    
    
    
72. XU Y, Wang YF, Liu YW, Dong R, et al
    The Impact of Delayed Transition From Noninvasive to Invasive Mechanical Ventilation on Hospital Mortality in Immunocompromised Patients With Sepsis.
    Crit Care Med. 2024 Aug 21. doi: 10.1097/CCM.0000000000006400.
    PubMed     Abstract available
    
    
    
73. STINEHART KR, Hyer JM, Joshi S, Brummel NE, et al
    Healthcare Use and Expenditures in Rural Survivors of Hospitalization for Sepsis.
    Crit Care Med. 2024 Aug 13. doi: 10.1097/CCM.0000000000006397.
    PubMed     Abstract available
    
    
    
74. WALLEY KR
    Lessons From the LIPid Intensive Drug therapy for Sepsis Pilot (LIPIDS-P) Trial.
    Crit Care Med. 2024;52:1303-1306.
    PubMed    
    
    
    
75. POLITO CC, Klompas M, Rhee C
    Advancing Global Validation and Implementation of Adult Sepsis Event Surveillance.
    Crit Care Med. 2024;52:1300-1303.
    PubMed    
    
    
    July 2024
76. 
    Machine Learning Models for Predicting Mortality in Sepsis: A Systematic Review: Erratum.
    Crit Care Med. 2024;52:e420.
    PubMed    
    
    
    
77. KLOMPAS M, Rhee C
    Victories and Opportunities in the Surviving Sepsis Campaign's Antibiotic Timing Guidance.
    Crit Care Med. 2024;52:1138-1141.
    PubMed    
    
    
    
78. KUBO K, Sakuraya M, Sugimoto H, Takahashi N, et al
    Benefits and Harms of Procalcitonin- or C-Reactive Protein-Guided Antimicrobial Discontinuation in Critically Ill Adults With Sepsis: A Systematic Review and Network Meta-Analysis.
    Crit Care Med. 2024 Jul 1. doi: 10.1097/CCM.0000000000006366.
    PubMed     Abstract available
    
    
    June 2024
79. GRAY AJ, Oatey K, Grahamslaw J, Irvine S, et al
    Albumin Versus Balanced Crystalloid for the Early Resuscitation of Sepsis: An Open Parallel-Group Randomized Feasibility Trial. The ABC-Sepsis Trial.
    Crit Care Med. 2024 Jun 24. doi: 10.1097/CCM.0000000000006348.
    PubMed     Abstract available
    
    
    
80. RHEE C, Filbin MR
    Can Procalcitonin and Other Biomarkers Help Rapidly Identify Sepsis Among Undifferentiated High-Risk Patients in the Emergency Department?
    Crit Care Med. 2024;52:979-982.
    PubMed    
    
    
    May 2024
81. ALRAWASHDEH M, Klompas M, Rhee C
    The Impact of Common Variations in Sequential Organ Failure Assessment Score Calculation on Sepsis Measurement Using Sepsis-3 Criteria: A Retrospective Analysis Using Electronic Health Record Data.
    Crit Care Med. 2024 May 23. doi: 10.1097/CCM.0000000000006338.
    PubMed     Abstract available
    
    
    April 2024
82. BOSCH NA, Pereira TV, Teja B
    Should Fludrocortisone be Added to Hydrocortisone in Septic Shock? Probably Yes, Based on Available Evidence.
    Crit Care Med. 2024;52:678-682.
    PubMed    
    
    
    
83. MILLER M, Melis MJ, Miller JRC, Kleyman A, et al
    Antibiotics, Sedatives, and Catecholamines Further Compromise Sepsis-Induced Immune Suppression in Peripheral Blood Mononuclear Cells.
    Crit Care Med. 2024;52:596-606.
    PubMed     Abstract available
    
    
    
84. LAI PC, Lai CH, Lai EC, Huang YT, et al
    Do We Need to Administer Fludrocortisone in Addition to Hydrocortisone in Adult Patients With Septic Shock? An Updated Systematic Review With Bayesian Network Meta-Analysis of Randomized Controlled Trials and an Observational Study With Target Trial E
    Crit Care Med. 2024;52:e193-e202.
    PubMed     Abstract available
    
    
    
85. DONALDSON LH, Vlok R, Sakurai K, Burrows M, et al
    Quantifying the Impact of Alternative Definitions of Sepsis-Associated Acute Kidney Injury on its Incidence and Outcomes: A Systematic Review and Meta-Analysis.
    Crit Care Med. 2024 Apr 1. doi: 10.1097/CCM.0000000000006284.
    PubMed     Abstract available
    
    
    March 2024
86. LEE SY, Park MH, Oh DK, Lim CM, et al
    Validation of Adult Sepsis Event and Epidemiologic Analysis of Sepsis Prevalence and Mortality Using Adult Sepsis Event's Electronic Health Records-Based Sequential Organ Failure Assessment Criteria: A Single-Center Study in South Korea.
    Crit Care Med. 2024 Mar 26. doi: 10.1097/CCM.0000000000006270.
    PubMed     Abstract available
    
    
    
87. GUIRGIS FW, Black LP, Henson M, Bertrand A, et al
    The Lipid Intensive Drug Therapy for Sepsis Phase II Pilot Clinical Trial.
    Crit Care Med. 2024 Mar 15. doi: 10.1097/CCM.0000000000006268.
    PubMed     Abstract available
    
    
    
88. NEYTON L, Spottiswoode N
    Advancing Sepsis Endotyping Globally: Lessons From a Prospective Study in Uganda.
    Crit Care Med. 2024;52:515-517.
    PubMed    
    
    
    
89. SEE EJ, Russell JA, Bellomo R, Lawler PR, et al
    Renin as a Prognostic and Predictive Biomarker in Sepsis: More Questions Than Answers?
    Crit Care Med. 2024;52:509-512.
    PubMed    
    
    
    
90. SOPIRALA MM, Estelle CD, Houston L
    Central Line-Associated Bloodstream Infection Misclassifications-Rethinking the Centers for Disease Control and Prevention's Central Line-Associated Bloodstream Infection Definition and Its Implications.
    Crit Care Med. 2024;52:357-361.
    PubMed     Abstract available
    
    
    February 2024
91. TAYLOR SP, Kowalkowski MA, Skewes S, Chou SH, et al
    Real-World Implications of Updated Surviving Sepsis Campaign Antibiotic Timing Recommendations.
    Crit Care Med. 2024 Feb 22. doi: 10.1097/CCM.0000000000006240.
    PubMed     Abstract available
    
    
    
92. BOLANAKI M, Winning J, Slagman A, Lehmann T, et al
    Biomarkers Improve Diagnostics of Sepsis in Adult Patients With Suspected Organ Dysfunction Based on the Quick Sepsis-Related Organ Failure Assessment (qSOFA) Score in the Emergency Department.
    Crit Care Med. 2024 Feb 7. doi: 10.1097/CCM.0000000000006216.
    PubMed     Abstract available
    
    
    
93. SHIME N, Inagawa T, MacLaren G
    Time to Reexamine the Definition of Sepsis?
    Crit Care Med. 2024;52:e107-e108.
    PubMed    
    
    
    
94. MASLOVE DM
    Echocardiography in the Management of Sepsis: Not All Black and White.
    Crit Care Med. 2024;52:348-350.
    PubMed    
    
    
    
95. BHAVANI SV, Mohr N
    Saved by the Bell-Automated Paging Alerts to Improve Sepsis Bundle Compliance.
    Crit Care Med. 2024;52:340-342.
    PubMed    
    
    
    
96. DE BACKER D, Deutschman CS, Hellman J, Myatra SN, et al
    Surviving Sepsis Campaign Research Priorities 2023.
    Crit Care Med. 2024;52:268-296.
    PubMed     Abstract available
    
    
    
97. BLANK SP, Blank RM
    Echocardiography Does not Reduce Mortality in Sepsis: A Re-Evaluation Using the Medical Information Mart for Intensive Care IV Dataset.
    Crit Care Med. 2024;52:248-257.
    PubMed     Abstract available
    
    
    January 2024
98. CHAUDHURI D, Nei AM, Rochwerg B, Balk RA, et al
    2024 Focused Update: Guidelines on Use of Corticosteroids in Sepsis, Acute Respiratory Distress Syndrome, and Community-Acquired Pneumonia.
    Crit Care Med. 2024 Jan 19. doi: 10.1097/CCM.0000000000006172.
    PubMed     Abstract available
    
    
    
99. CHAUDHURI D, Nei AM, Rochwerg B, Balk RA, et al
    Executive Summary: Guidelines on Use of Corticosteroids in Critically Ill Patients With Sepsis, Acute Respiratory Distress Syndrome, and Community-Acquired Pneumonia Focused Update 2024.
    Crit Care Med. 2024 Jan 19. doi: 10.1097/CCM.0000000000006171.
    PubMed    
    
    
    December 2023
100. BRONICKI RA, Tume S, Gomez H, Dezfulian C, et al
     Application of Cardiovascular Physiology to the Critically Ill Patient.
     Crit Care Med. 2023 Dec 21. doi: 10.1097/CCM.0000000000006136.
     PubMed     Abstract available
     
     
     
101. LEISMAN DE, Deng H, Lee AH, Flynn MH, et al
     Effect of Automated Real-Time Feedback on Early-Sepsis Care: A Pragmatic Clinical Trial.
     Crit Care Med. 2023 Dec 13. doi: 10.1097/CCM.0000000000006057.
     PubMed     Abstract available
     
     
     
102. JHA AK
     Immediate Fluid Bolus or Norepinephrine in Endotoxic Shock.
     Crit Care Med. 2023;51:e279-e280.
     PubMed    
     
     
     
103. ZHAO JO, Patel BK, Krishack P, Stutz MR, et al
     Identification of Clinically Significant Cytokine Signature Clusters in Patients With Septic Shock.
     Crit Care Med. 2023;51:e253-e263.
     PubMed     Abstract available
     
     
     
104. DONY CA, Illipparambil LC, Maeda T, Mroczek SK, et al
     Plasma Nitric Oxide Consumption Is Elevated and Associated With Adverse Outcomes in Critically Ill Patients.
     Crit Care Med. 2023;51:1706-1715.
     PubMed     Abstract available
     
     
     
105. PODD BS, Banks RK, Reeder R, Telford R, et al
     Early, Persistent Lymphopenia Is Associated With Prolonged Multiple Organ Failure and Mortality in Septic Children.
     Crit Care Med. 2023;51:1766-1776.
     PubMed     Abstract available
     
     
     November 2023
106. BUSSE LW, Schaich CL, Chappell MC, McCurdy MT, et al
     Association of Active Renin Content With Mortality in Critically Ill Patients: A Post hoc Analysis of the Vitamin C, Thiamine, and Steroids in Sepsis Trial.
     Crit Care Med. 2023 Nov 10. doi: 10.1097/CCM.0000000000006095.
     PubMed     Abstract available
     
     
     
107. FAN TH, Premraj L, Roberts J, Lydston M, et al
     In-Hospital Neurologic Complications, Neuromonitoring, and Long-Term Neurologic Outcomes in Patients With Sepsis: A Systematic Review and Meta-Analysis.
     Crit Care Med. 2023 Nov 3. doi: 10.1097/CCM.0000000000006096.
     PubMed     Abstract available
     
     
     
108. RUAN H, Zhang Q, Ran X
     Unraveling the Obesity Paradox in Sepsis Patients: Insights Into the Role of Body Composition and Adipose Distribution.
     Crit Care Med. 2023;51:e249-e250.
     PubMed    
     
     
     
109. ANESI GL, Admon AJ
     Unpacking Regionalization of Sepsis Care Using Hospital Capability Assessments.
     Crit Care Med. 2023;51:1594-1596.
     PubMed    
     
     
     
110. PALMER ES, Agus MSD
     Running Wide Open: Strong Evidence for Bolus Fluids Selection in Pediatric Sepsis.
     Crit Care Med. 2023;51:1587-1589.
     PubMed    
     
     
     
111. SANKAR J, Muralidharan J, Lalitha AV, Rameshkumar R, et al
     Multiple Electrolytes Solution Versus Saline as Bolus Fluid for Resuscitation in Pediatric Septic Shock: A Multicenter Randomized Clinical Trial.
     Crit Care Med. 2023;51:1449-1460.
     PubMed     Abstract available
     
     
     
112. MAYER S, Bonhag C, Jenkins P, Cornett B, et al
     Probiotic-Associated Central Venous Catheter Bloodstream Infections Lead to Increased Mortality in the ICU.
     Crit Care Med. 2023;51:1469-1478.
     PubMed     Abstract available
     
     
     October 2023
113. HONORE PM, Bousbiat I, Perriens E, Orman A, et al
     Potential Confounders in Study Stating That Levels of Prokineticin-2 Were Significantly Higher in Septic Shock Than Sepsis.
     Crit Care Med. 2023;51:e206-e207.
     PubMed    
     
     
     
114. SCRUTH E
     Life After Sepsis: The Journey Continues.
     Crit Care Med. 2023;51:1439-1441.
     PubMed    
     
     
     September 2023
115. BARLETTA JF
     Empiric Carbapenem Therapy for Sepsis: Are We Winning the Battle at the Expense of the War?
     Crit Care Med. 2023;51:1275-1277.
     PubMed    
     
     
     
116. LAWANDI A
     Bloodstream Infections in Sepsis: Better the Devil You Know.
     Crit Care Med. 2023;51:1261-1263.
     PubMed    
     
     
     August 2023
117. CUMMINGS MJ, Bakamutumaho B, Tomoiaga AS, Owor N, et al
     A Transcriptomic Classifier Model Identifies High-Risk Endotypes in a Prospective Study of Sepsis in Uganda.
     Crit Care Med. 2023 Aug 7. doi: 10.1097/CCM.0000000000006023.
     PubMed     Abstract available
     
     
     
118. LEE DH
     Obesity Paradox in Sepsis: Role of Adipose Tissue in Storing Mitochondrial Toxins.
     Crit Care Med. 2023;51:e172-e174.
     PubMed    
     
     
     
119. LYONS NB, Proctor KG
     Are the Outcomes of a Pig Endotoxemia Model Applicable to Human Sepsis?
     Crit Care Med. 2023;51:1102-1104.
     PubMed    
     
     
     
120. KALIL AC, Simpson SQ
     Vitamin C and Sepsis: Is Bayesian Reanalysis Useful to Translate the Results of Frequentist Randomized Trials?
     Crit Care Med. 2023;51:1100-1102.
     PubMed    
     
     
     
121. OSPINA-TASCON GA, Aldana JL, Garcia Marin AF, Calderon-Tapia LE, et al
     Immediate Norepinephrine in Endotoxic Shock: Effects on Regional and Microcirculatory Flow.
     Crit Care Med. 2023;51:e157-e168.
     PubMed     Abstract available
     
     
     July 2023
122. CHEN JJ, Lai PC, Lee TH, Huang YT, et al
     Blood Purification for Adult Patients With Severe Infection or Sepsis/Septic Shock: A Network Meta-Analysis of Randomized Controlled Trials.
     Crit Care Med. 2023 Jul 20. doi: 10.1097/CCM.0000000000005991.
     PubMed     Abstract available
     
     
     
123. LAWANDI A, Oshiro M, Warner S, Diao G, et al
     Reliability of Admission Procalcitonin Testing for Capturing Bacteremia Across the Sepsis Spectrum: Real-World Utilization and Performance Characteristics, 65 U.S. Hospitals, 2008-2017.
     Crit Care Med. 2023 Jul 3. doi: 10.1097/CCM.0000000000005968.
     PubMed     Abstract available
     
     
     June 2023
124. OFOMA UR, Deych E, Mohr NM, Walkey A, et al
     The Relationship Between Hospital Capability and Mortality in Sepsis: Development of a Sepsis-Related Hospital Capability Index.
     Crit Care Med. 2023 Jun 20. doi: 10.1097/CCM.0000000000005973.
     PubMed     Abstract available
     
     
     
125. KUREMATSU K, Ikematsu Y
     Quality of Life of Sepsis Survivors.
     Crit Care Med. 2023 Jun 14. doi: 10.1097/CCM.0000000000005944.
     PubMed     Abstract available
     
     
     
126. WARD A, Chemparathy A, Seneviratne M, Gaskari S, et al
     The Association Between Central Line-Associated Bloodstream Infection and Central Line Access.
     Crit Care Med. 2023;51:787-796.
     PubMed     Abstract available
     
     
     May 2023
127. UMEMURA Y, Yamakawa K, Tanaka Y, Yoshimura J, et al
     Efficacy of Carbapenems Compared With Noncarbapenem Broad-Spectrum Beta-Lactam Antibiotics as Initial Antibiotic Therapy Against Sepsis: A Nationwide Observational Study.
     Crit Care Med. 2023 May 26. doi: 10.1097/CCM.0000000000005932.
     PubMed     Abstract available
     
     
     April 2023
128. OHBE H, Sasabuchi Y, Doi K, Matsui H, et al
     Association Between Levels of Intensive Care and In-Hospital Mortality in Patients Hospitalized for Sepsis Stratified by Sequential Organ Failure Assessment Scores.
     Crit Care Med. 2023 Apr 28. doi: 10.1097/CCM.0000000000005886.
     PubMed     Abstract available
     
     
     
129. WARDI G, Owens R, Josef C, Malhotra A, et al
     Bringing the Promise of Artificial Intelligence to Critical Care: What the Experience With Sepsis Analytics Can Teach Us.
     Crit Care Med. 2023 Apr 26. doi: 10.1097/CCM.0000000000005894.
     PubMed    
     
     
     
130. ANGRIMAN F, Muttalib F, Lamontagne F, Adhikari NKJ, et al
     IV Vitamin C in Adults With Sepsis: A Bayesian Reanalysis of a Randomized Controlled Trial.
     Crit Care Med. 2023 Apr 7. doi: 10.1097/CCM.0000000000005871.
     PubMed     Abstract available
     
     
     
131. OHNUMA T, Chihara S, Costin B, Treggiari M, et al
     Epidemiology, Resistance Profiles, and Outcomes of Bloodstream Infections in Community-Onset Sepsis in the United States.
     Crit Care Med. 2023 Apr 5. doi: 10.1097/CCM.0000000000005870.
     PubMed     Abstract available
     
     
     
132. BHAVANI SV
     A Need for Prospective Long-Term Data to Characterize Cardiovascular Risk Factors in Sepsis Survivors.
     Crit Care Med. 2023;51:549-550.
     PubMed    
     
     
     
133. DELLINGER RP, Rhodes A, Evans L, Alhazzani W, et al
     Surviving Sepsis Campaign.
     Crit Care Med. 2023;51:431-444.
     PubMed    
     
     
     
134. JOUFFROY R, Gueye P, Vivien B
     Turning Back the Clock: Prehospital Antibiotics for Patients With Septic Shock: Let Us Act at the Right Time.
     Crit Care Med. 2023;51:e97-e98.
     PubMed    
     
     
     March 2023
135. HUANG YH, Chen CJ, Shao SC, Li CH, et al
     Comparison of the Diagnostic Accuracies of Monocyte Distribution Width, Procalcitonin, and C-Reactive Protein for Sepsis: A Systematic Review and Meta-Analysis.
     Crit Care Med. 2023 Mar 6. doi: 10.1097/CCM.0000000000005820.
     PubMed     Abstract available
     
     

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