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  Sepsis

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Articles published in Crit Care Med

Retrieve available abstracts of 491 articles:
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Single Articles


    June 2020
  1. CAWCUTT KA, Beachy M, Peitz GJ
    Antibiotic Delivery in Sepsis: How Do We Improve?
    Crit Care Med. 2020;48:e540-e541.
    PubMed    


  2. COOKSLEY T, Haji-Michael P
    Oncologic Sepsis on the ICU: Two Decades of Improving Outcomes.
    Crit Care Med. 2020;48:925-926.
    PubMed    


  3. SEE H, Slonim AD
    Evaluating the Effect of Policy Changes on Sepsis Outcomes.
    Crit Care Med. 2020;48:919-920.
    PubMed    


  4. RHEE C, Strich JR, Klompas M, Yealy DM, et al
    SEP-1 Has Brought Much Needed Attention to Improving Sepsis Care...But Now Is the Time to Improve SEP-1.
    Crit Care Med. 2020;48:779-782.
    PubMed    


    May 2020
  5. EHLER J, Petzold A, Sharshar T, Ely EW, et al
    Biomarker Panel to Differentiate Brain Injury From Brain Dysfunction in Patients With Sepsis-Associated Encephalopathy.
    Crit Care Med. 2020;48:e436-e437.
    PubMed    


    April 2020
  6. RUSH B, Danziger J, Walley KR, Kumar A, et al
    Treatment in Disproportionately Minority Hospitals Is Associated With Increased Risk of Mortality in Sepsis: A National Analysis.
    Crit Care Med. 2020 Apr 28. doi: 10.1097/CCM.0000000000004375.
    PubMed     Abstract available


  7. OSBORN TM
    Sepsis Mandates Help Clinicians and Patients.
    Crit Care Med. 2020 Apr 17. doi: 10.1097/CCM.0000000000004342.
    PubMed    


  8. LEMIALE V, Pons S, Mirouse A, Tudesq JJ, et al
    Sepsis and Septic Shock in Patients With Malignancies: A Groupe de Recherche Respiratoire en Reanimation Onco-Hematologique Study.
    Crit Care Med. 2020 Apr 17. doi: 10.1097/CCM.0000000000004322.
    PubMed     Abstract available


  9. LINDELL RB, Nishisaki A, Weiss SL, Traynor DM, et al
    Risk of Mortality in Immunocompromised Children With Severe Sepsis and Septic Shock.
    Crit Care Med. 2020 Apr 14. doi: 10.1097/CCM.0000000000004329.
    PubMed     Abstract available


  10. CHINAI B, Gaughan J, Schorr C
    Implementation of the Affordable Care Act: A Comparison of Outcomes in Patients With Severe Sepsis and Septic Shock Using the National Inpatient Sample.
    Crit Care Med. 2020 Apr 9. doi: 10.1097/CCM.0000000000004310.
    PubMed     Abstract available


  11. GALIATSATOS P, Follin A, Alghanim F, Sherry M, et al
    The Association Between Neighborhood Socioeconomic Disadvantage and Readmissions for Patients Hospitalized With Sepsis.
    Crit Care Med. 2020 Apr 8. doi: 10.1097/CCM.0000000000004307.
    PubMed     Abstract available


  12. STRICH JR, Wang J, Eichacker PQ
    Sepsis Bundles That Focus on Clinician Judgment and Proven Interventions Are Needed to Increase Bundle Compliance and Effectiveness.
    Crit Care Med. 2020;48:602-605.
    PubMed    


  13. ROSENQVIST M, Bengtsson-Toni M, Tham J, Lanbeck P, et al
    Improved Outcomes After Regional Implementation of Sepsis Alert: A Novel Triage Model.
    Crit Care Med. 2020;48:484-490.
    PubMed     Abstract available


    March 2020
  14. ALHAZZANI W, Moller MH, Arabi YM, Loeb M, et al
    Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19).
    Crit Care Med. 2020 Mar 27. doi: 10.1097/CCM.0000000000004363.
    PubMed     Abstract available


  15. HENDRICKSON CM, Matthay MA
    Potential Value of Biomarker Signatures in Sepsis and Acute Respiratory Distress Syndrome in Children and Adults.
    Crit Care Med. 2020;48:428-430.
    PubMed    


  16. BUSCH LM, Kalil AC, Kadri SS
    Predicting Sepsis Mortality and Costs Using Medicare Claims: A Method to the Madness.
    Crit Care Med. 2020;48:424-426.
    PubMed    


  17. LEVY MM
    Identifying the Burden of Sepsis With Big Data.
    Crit Care Med. 2020;48:422-423.
    PubMed    


  18. RHEE C, Klompas M
    The Eye-Popping Costs Associated With Sepsis Diagnoses Among Medicare Beneficiaries.
    Crit Care Med. 2020;48:420-422.
    PubMed    


  19. WHITNEY JE, Zhang B, Koterba N, Chen F, et al
    Systemic Endothelial Activation Is Associated With Early Acute Respiratory Distress Syndrome in Children With Extrapulmonary Sepsis.
    Crit Care Med. 2020;48:344-352.
    PubMed     Abstract available


  20. BUCHMAN TG, Simpson SQ, Sciarretta KL, Finne KP, et al
    Sepsis Among Medicare Beneficiaries: 3. The Methods, Models, and Forecasts of Sepsis, 2012-2018.
    Crit Care Med. 2020;48:302-318.
    PubMed     Abstract available


  21. BUCHMAN TG, Simpson SQ, Sciarretta KL, Finne KP, et al
    Sepsis Among Medicare Beneficiaries: 2. The Trajectories of Sepsis, 2012-2018.
    Crit Care Med. 2020;48:289-301.
    PubMed     Abstract available


  22. BUCHMAN TG, Simpson SQ, Sciarretta KL, Finne KP, et al
    Sepsis Among Medicare Beneficiaries: 1. The Burdens of Sepsis, 2012-2018.
    Crit Care Med. 2020;48:276-288.
    PubMed     Abstract available


    February 2020
  23. CARLTON EF, Donnelly JP, Hensley MK, Cornell TT, et al
    New Medical Device Acquisition During Pediatric Severe Sepsis Hospitalizations.
    Crit Care Med. 2020 Feb 27. doi: 10.1097/CCM.0000000000004272.
    PubMed     Abstract available


  24. BINNIE A, Tsang JLY, Hu P, Carrasqueiro G, et al
    Epigenetics of Sepsis.
    Crit Care Med. 2020 Feb 20. doi: 10.1097/CCM.0000000000004247.
    PubMed     Abstract available


  25. KWON MY, Ghanta S, Ng J, Tsoyi K, et al
    Expression of Stromal Cell-Derived Factor-1 by Mesenchymal Stromal Cells Impacts Neutrophil Function During Sepsis.
    Crit Care Med. 2020 Feb 20. doi: 10.1097/CCM.0000000000004244.
    PubMed     Abstract available


  26. ISHII J, Ohshimo S, Shime N
    Potential Confounders for Applying a Novel Sepsis Care Quality Improvement Program.
    Crit Care Med. 2020;48:e161-e162.
    PubMed    


  27. BUCHMAN TG, Zehnbauer BA
    Exploring the Epigenetics of Severe Sepsis: First Step in a Long Journey.
    Crit Care Med. 2020;48:254-255.
    PubMed    


  28. REYNA MA, Josef CS, Jeter R, Shashikumar SP, et al
    Early Prediction of Sepsis From Clinical Data: The PhysioNet/Computing in Cardiology Challenge 2019.
    Crit Care Med. 2020;48:210-217.
    PubMed     Abstract available


  29. PRASAD PA, Fang MC, Abe-Jones Y, Calfee CS, et al
    Time to Recognition of Sepsis in the Emergency Department Using Electronic Health Record Data: A Comparative Analysis of Systemic Inflammatory Response Syndrome, Sequential Organ Failure Assessment, and Quick Sequential Organ Failure Assessment.
    Crit Care Med. 2020;48:200-209.
    PubMed     Abstract available


  30. BINNIE A, Walsh CJ, Hu P, Dwivedi DJ, et al
    Epigenetic Profiling in Severe Sepsis: A Pilot Study of DNA Methylation Profiles in Critical Illness.
    Crit Care Med. 2020;48:142-150.
    PubMed     Abstract available


  31. SARIA S, Henry KE
    Too Many Definitions of Sepsis: Can Machine Learning Leverage the Electronic Health Record to Increase Accuracy and Bring Consensus?
    Crit Care Med. 2020;48:137-141.
    PubMed    


    January 2020
  32. ROSENQVIST M, Bengtsson-Toni M, Tham J, Lanbeck P, et al
    Improved Outcomes After Regional Implementation of Sepsis Alert: A Novel Triage Model.
    Crit Care Med. 2020 Jan 13. doi: 10.1097/CCM.0000000000004179.
    PubMed     Abstract available


    December 2019
  33. REYNA MA, Josef CS, Jeter R, Shashikumar SP, et al
    Early Prediction of Sepsis From Clinical Data: The PhysioNet/Computing in Cardiology Challenge 2019.
    Crit Care Med. 2019 Dec 17. doi: 10.1097/CCM.0000000000004145.
    PubMed     Abstract available


  34. BINNIE A, Walsh CJ, Hu P, Dwivedi DJ, et al
    Epigenetic Profiling in Severe Sepsis: A Pilot Study of DNA Methylation Profiles in Critical Illness.
    Crit Care Med. 2019 Dec 11. doi: 10.1097/CCM.0000000000004097.
    PubMed     Abstract available


  35. XIE J, Wang H, Kang Y, Zhou L, et al
    The Epidemiology of Sepsis in Chinese ICUs: A National Cross-Sectional Survey.
    Crit Care Med. 2019 Dec 5. doi: 10.1097/CCM.0000000000004155.
    PubMed     Abstract available


  36. PRASAD PA, Fang MC, Abe-Jones Y, Calfee CS, et al
    Time to Recognition of Sepsis in the Emergency Department Using Electronic Health Record Data: A Comparative Analysis of Systemic Inflammatory Response Syndrome, Sequential Organ Failure Assessment, and Quick Sequential Organ Failure Assessment.
    Crit Care Med. 2019 Dec 3. doi: 10.1097/CCM.0000000000004132.
    PubMed     Abstract available


  37. OUD L
    The Impact of Atrial Fibrillation on Short-Term Mortality and Resource Utilization in Sepsis.
    Crit Care Med. 2019;47:e1032.
    PubMed    


    November 2019
  38. PROUT AJ, Talisa VB, Carcillo JA, Decker BK, et al
    Bacterial and Fungal Etiology of Sepsis in Children in the United States: Reconsidering Empiric Therapy.
    Crit Care Med. 2019 Nov 27. doi: 10.1097/CCM.0000000000004140.
    PubMed     Abstract available


  39. SHUBIN NJ, Navalkar K, Sampson D, Yager TD, et al
    Serum Protein Changes in Pediatric Sepsis Patients Identified With an Aptamer-Based Multiplexed Proteomic Approach.
    Crit Care Med. 2019 Nov 8. doi: 10.1097/CCM.0000000000004083.
    PubMed     Abstract available


  40. OSUCHOWSKI MF, Rosengart MR
    Change Is the Only Constant: How to Adopt the New Trends in Sepsis Modeling?
    Crit Care Med. 2019;47:1673-1675.
    PubMed    


  41. HOPKINS RO
    Acquired Brain Injury Following Sepsis.
    Crit Care Med. 2019;47:1658-1659.
    PubMed    


  42. SIMPSON SQ
    Sepsis Biomarkers and Physician Judgment in the Emergency Room.
    Crit Care Med. 2019;47:1656-1657.
    PubMed    


    October 2019
  43. SHIMADA T, Topchiy E, Leung AKK, Kong HJ, et al
    Very Low Density Lipoprotein Receptor Sequesters Lipopolysaccharide Into Adipose Tissue During Sepsis.
    Crit Care Med. 2019 Oct 23. doi: 10.1097/CCM.0000000000004064.
    PubMed     Abstract available


  44. LI X, Zhu J, Tian L, Ma X, et al
    Agmatine Protects Against the Progression of Sepsis Through the Imidazoline I2 Receptor-Ribosomal S6 Kinase 2-Nuclear Factor-kappaB Signaling Pathway.
    Crit Care Med. 2019 Oct 21. doi: 10.1097/CCM.0000000000004065.
    PubMed     Abstract available


  45. YAN X, Tu H, Liu Y, Chen T, et al
    Interleukin-17D Aggravates Sepsis by Inhibiting Macrophage Phagocytosis.
    Crit Care Med. 2019 Oct 17. doi: 10.1097/CCM.0000000000004070.
    PubMed     Abstract available


  46. NUSSHAG C, Rupp C, Schmitt F, Krautkramer E, et al
    Cell Cycle Biomarkers and Soluble Urokinase-Type Plasminogen Activator Receptor for the Prediction of Sepsis-Induced Acute Kidney Injury Requiring Renal Replacement Therapy: A Prospective, Exploratory Study.
    Crit Care Med. 2019 Oct 4. doi: 10.1097/CCM.0000000000004042.
    PubMed     Abstract available


  47. PELTAN ID, Liu VX
    More Than We Bargained For: The "Dominating" Cost Effectiveness of Sepsis Quality Improvement?
    Crit Care Med. 2019;47:1464-1467.
    PubMed    


  48. PARKER RI
    Cancer and Sepsis: Adding Insult to Injury-As if Either Alone Were Not Enough?
    Crit Care Med. 2019;47:1452-1453.
    PubMed    


  49. LEVY MM
    Implementation of Sepsis Bundles: Just Do It!!
    Crit Care Med. 2019;47:1450-1451.
    PubMed    


    September 2019
  50. OH SY, Cho S, Kim GH, Jang EJ, et al
    Incidence and Outcomes of Sepsis in Korea: A Nationwide Cohort Study From 2007 to 2016.
    Crit Care Med. 2019 Sep 30. doi: 10.1097/CCM.0000000000004041.
    PubMed     Abstract available


  51. GOULDEN R
    Alternative Explanations for the Obesity Paradox in Sepsis.
    Crit Care Med. 2019;47:e790.
    PubMed    


  52. PITTA MR, Campos FM
    Comment on "Does Obesity Protect Against Death in Sepsis? A Retrospective Cohort Study of 55,038 Adult Patients".
    Crit Care Med. 2019;47:e789-e790.
    PubMed    


  53. SURESH K, D'Alessio F
    Immune Checkpoint Inhibitor Use in Sepsis: Monitoring Immune Checkpoint Inhibitor Toxicity.
    Crit Care Med. 2019;47:e788.
    PubMed    


  54. OUD L
    Reporting Epidemiologic Studies in Sepsis Combining the International Classification of Diseases, 9th Edition and International Classification of Diseases, 10th Edition Codes.
    Crit Care Med. 2019;47:e785.
    PubMed    


    August 2019
  55. KUTTAB HI, Lykins JD, Hughes MD, Wroblewski K, et al
    Evaluation and Predictors of Fluid Resuscitation in Patients With Severe Sepsis and Septic Shock.
    Crit Care Med. 2019 Aug 7. doi: 10.1097/CCM.0000000000003960.
    PubMed     Abstract available


  56. STORTZ JA, Hollen MK, Nacionales DC, Horiguchi H, et al
    Old Mice Demonstrate Organ Dysfunction as well as Prolonged Inflammation, Immunosuppression, and Weight Loss in a Modified Surgical Sepsis Model.
    Crit Care Med. 2019 Aug 5. doi: 10.1097/CCM.0000000000003926.
    PubMed     Abstract available


  57. GIANNINI HM, Ginestra JC, Chivers C, Draugelis M, et al
    A Machine Learning Algorithm to Predict Severe Sepsis and Septic Shock: Development, Implementation, and Impact on Clinical Practice.
    Crit Care Med. 2019 Aug 5. doi: 10.1097/CCM.0000000000003891.
    PubMed     Abstract available


  58. EHLENBACH WJ, Sonnen JA, Montine TJ, Larson EB, et al
    Association Between Sepsis and Microvascular Brain Injury.
    Crit Care Med. 2019 Aug 5. doi: 10.1097/CCM.0000000000003924.
    PubMed     Abstract available


  59. WEISS SL, Zhang D, Bush J, Graham K, et al
    Persistent Mitochondrial Dysfunction Linked to Prolonged Organ Dysfunction in Pediatric Sepsis.
    Crit Care Med. 2019 Aug 2. doi: 10.1097/CCM.0000000000003931.
    PubMed     Abstract available


  60. SAMUELS DC, Hulgan T, Fessel JP, Billings FT 4th, et al
    Mitochondrial DNA Haplogroups and Delirium During Sepsis.
    Crit Care Med. 2019;47:1065-1071.
    PubMed     Abstract available


  61. GAZMURI RJ, Anez de Gomez CI, Siddiqui M, Schechtman J, et al
    Severe Sepsis and Septic Shock Early Management Bundle Risks Aiding Vasopressor Misuse.
    Crit Care Med. 2019;47:e717.
    PubMed    


  62. LEE JT, Mikkelsen ME
    Risk Stratification Tools in Sepsis: From Acute Physiology and Chronic Health Evaluation to Quick Sequential Organ Failure Assessment.
    Crit Care Med. 2019;47:1159-1161.
    PubMed    


  63. PARKER RI
    Sepsis: From Little Findings Big Ideas Grow.
    Crit Care Med. 2019;47:1152-1153.
    PubMed    


    July 2019
  64. MIAO H, Shi J, Wang C, Lu G, et al
    Continuous Renal Replacement Therapy in Pediatric Severe Sepsis: A Propensity Score-Matched Prospective Multicenter Cohort Study in the PICU.
    Crit Care Med. 2019 Jul 31. doi: 10.1097/CCM.0000000000003901.
    PubMed     Abstract available


  65. PEPPER DJ, Sun J, Cui X, Welsh J, et al
    Antibiotic- and Fluid-Focused Bundles Potentially Improve Sepsis Management, but High-Quality Evidence Is Lacking for the Specificity Required in the Centers for Medicare and Medicaid Service's Sepsis Bundle (SEP-1).
    Crit Care Med. 2019 Jul 31. doi: 10.1097/CCM.0000000000003892.
    PubMed     Abstract available


  66. HENSLEY MK, Donnelly JP, Carlton EF, Prescott HC, et al
    Epidemiology and Outcomes of Cancer-Related Versus Non-Cancer-Related Sepsis Hospitalizations.
    Crit Care Med. 2019 Jul 25. doi: 10.1097/CCM.0000000000003896.
    PubMed     Abstract available


  67. PARK CHL, de Almeida JP, de Oliveira GQ, Rizk SI, et al
    Lactated Ringer's Versus 4% Albumin on Lactated Ringer's in Early Sepsis Therapy in Cancer Patients: A Pilot Single-Center Randomized Trial.
    Crit Care Med. 2019 Jul 25. doi: 10.1097/CCM.0000000000003900.
    PubMed     Abstract available


  68. KASHIOURIS MG, Zemore Z, Kimball Z, Stefanou C, et al
    Supply Chain Delays in Antimicrobial Administration After the Initial Clinician Order and Mortality in Patients With Sepsis.
    Crit Care Med. 2019 Jul 24. doi: 10.1097/CCM.0000000000003921.
    PubMed     Abstract available


  69. AFSHAR M, Arain E, Ye C, Gilbert E, et al
    Patient Outcomes and Cost-Effectiveness of a Sepsis Care Quality Improvement Program in a Health System.
    Crit Care Med. 2019 Jul 15. doi: 10.1097/CCM.0000000000003919.
    PubMed     Abstract available


  70. BEALE R
    Enough Is As Good As a Feast.
    Crit Care Med. 2019;47:1004-1006.
    PubMed    


  71. MUTHUMALAIAPPAN K
    Efficacy of Mesenchymal Stem/Stromal Cell Infusion in Septic Patients Is a Puzzle Worthy of Attention.
    Crit Care Med. 2019;47:1001-1002.
    PubMed    


  72. TAPIA P, Gatica S, Cortes-Rivera C, Otero C, et al
    Circulating Endothelial Cells From Septic Shock Patients Convert to Fibroblasts Are Associated With the Resuscitation Fluid Dose and Are Biomarkers for Survival Prediction.
    Crit Care Med. 2019;47:942-950.
    PubMed     Abstract available


  73. SCHLOSSER K, Wang JP, Dos Santos C, Walley KR, et al
    Effects of Mesenchymal Stem Cell Treatment on Systemic Cytokine Levels in a Phase 1 Dose Escalation Safety Trial of Septic Shock Patients.
    Crit Care Med. 2019;47:918-925.
    PubMed     Abstract available


    June 2019
  74. ANTCLIFFE DB, Gordon AC
    Why Understanding Sepsis Endotypes Is Important for Steroid Trials in Septic Shock?
    Crit Care Med. 2019 Jun 3. doi: 10.1097/CCM.0000000000003833.
    PubMed    


  75. DORNAS W
    Damaging Effects of Oxygen in Induced Sepsis-Like Condition.
    Crit Care Med. 2019;47:e535-e536.
    PubMed    


  76. JOFFE AR, deCaen A
    Not Enough Evidence to Use Plasma Exchange for Sepsis or Thrombocytopenia-Associated Multiple Organ Failure in Children.
    Crit Care Med. 2019;47:e533-e534.
    PubMed    


  77. BERG RMG, Asghar MS
    Luxury Perfusion in Patients With Sepsis?
    Crit Care Med. 2019;47:e533.
    PubMed    


  78. LI S, Wang S, Priyanka P, Kellum JA, et al
    Acute Kidney Injury in Critically Ill Patients After Noncardiac Major Surgery: Early Versus Late Onset.
    Crit Care Med. 2019;47:e437-e444.
    PubMed     Abstract available


    May 2019
  79. RHEE C, Wang R, Zhang Z, Fram D, et al
    Epidemiology of Hospital-Onset Versus Community-Onset Sepsis in U.S. Hospitals and Association With Mortality: A Retrospective Analysis Using Electronic Clinical Data.
    Crit Care Med. 2019 May 24. doi: 10.1097/CCM.0000000000003817.
    PubMed     Abstract available


  80. GINESTRA JC, Giannini HM, Schweickert WD, Meadows L, et al
    Clinician Perception of a Machine Learning-Based Early Warning System Designed to Predict Severe Sepsis and Septic Shock.
    Crit Care Med. 2019 May 24. doi: 10.1097/CCM.0000000000003803.
    PubMed     Abstract available


  81. CROUSER ED, Parrillo JE, Seymour CW, Angus DC, et al
    Monocyte Distribution Width: A Novel Indicator of Sepsis-2 and Sepsis-3 in High-Risk Emergency Department Patients.
    Crit Care Med. 2019 May 17. doi: 10.1097/CCM.0000000000003799.
    PubMed     Abstract available


  82. DESAI R, Hanna B, Singh S, Omar A, et al
    Trends and Outcomes in Sepsis Hospitalizations With and Without Atrial Fibrillation: A Nationwide Inpatient Analysis.
    Crit Care Med. 2019 May 13. doi: 10.1097/CCM.0000000000003806.
    PubMed     Abstract available


  83. SIMPSON SQ
    Sepsis Epidemiology From Administrative Data: Going, Going....
    Crit Care Med. 2019;47:739-740.
    PubMed    


  84. CROUSER ED, Caldwell CC, Hotchkiss RS
    What Is the Skinny on Obesity During Sepsis?
    Crit Care Med. 2019;47:735-736.
    PubMed    


  85. CAWCUTT KA, Kalil AC
    Saved From Sepsis: Can Immunotherapy Improve Acute and Postacute Outcomes?
    Crit Care Med. 2019;47:733-735.
    PubMed    


  86. WOOLUM JA, Flannery AH
    The authors reply.
    Crit Care Med. 2019;47:e435-e436.
    PubMed    


  87. PATEL JJ, Bergl P
    Thiamine and Difficulties in Differentiating Type A From B Lactic Acidosis.
    Crit Care Med. 2019;47:e434-e435.
    PubMed    


  88. MORELLI A, Sanfilippo F, Rehberg S, Ertmer C, et al
    The authors reply.
    Crit Care Med. 2019;47:e432-e433.
    PubMed    


  89. PETITJEANS F, Leroy S, Geloen A, Pichot C, et al
    On the Right Track, Finally?
    Crit Care Med. 2019;47:e431-e432.
    PubMed    


  90. ROSSAINT J, Zarbock A
    A Novel Approach for the Targeted Inhibition of Platelet Activation-Separating the Good From the Bad.
    Crit Care Med. 2019;47:741-743.
    PubMed    


  91. GRUMAZ S, Grumaz C, Vainshtein Y, Stevens P, et al
    Enhanced Performance of Next-Generation Sequencing Diagnostics Compared With Standard of Care Microbiological Diagnostics in Patients Suffering From Septic Shock.
    Crit Care Med. 2019;47:e394-e402.
    PubMed     Abstract available


    April 2019
  92. CORL KA, Prodromou M, Merchant RC, Gareen I, et al
    The Restrictive IV Fluid Trial in Severe Sepsis and Septic Shock (RIFTS): A Randomized Pilot Study.
    Crit Care Med. 2019 Apr 12. doi: 10.1097/CCM.0000000000003779.
    PubMed     Abstract available


  93. HIGGINS AM, Peake SL, Bellomo R, Cooper DJ, et al
    Quality of Life and 1-Year Survival in Patients With Early Septic Shock: Long-Term Follow-Up of the Australasian Resuscitation in Sepsis Evaluation Trial.
    Crit Care Med. 2019 Apr 8. doi: 10.1097/CCM.0000000000003762.
    PubMed     Abstract available


  94. WIEDERMANN CJ
    Hypoalbuminemia and the Risk of Acute Kidney Injury in Sepsis.
    Crit Care Med. 2019;47:e377-e378.
    PubMed    


  95. ARGENT AC
    Readmission After Hospitalization for Pediatric Severe Sepsis-Data From a U.S. Database.
    Crit Care Med. 2019;47:612-613.
    PubMed    


  96. BAUER PR
    The Sicker Are Sicker: A Tale of Late Outcome After Sepsis.
    Crit Care Med. 2019;47:610-611.
    PubMed    


  97. HURST SD, Coopersmith CM
    Can We Compare Sepsis Outcomes on a Hospital Level If Documentation Is Variable (or Inaccurate)?
    Crit Care Med. 2019;47:599-600.
    PubMed    


  98. FISHER J, Linder A, Caironi P, Russell JA, et al
    The authors reply.
    Crit Care Med. 2019;47:e378-e379.
    PubMed    


  99. MENARD CE, Kumar A, Houston DS, Turgeon AF, et al
    Evolution and Impact of Thrombocytopenia in Septic Shock: A Retrospective Cohort Study.
    Crit Care Med. 2019;47:558-565.
    PubMed     Abstract available


  100. LEIJTE GP, Kiers D, van der Heijden W, Jansen A, et al
    Treatment With Acetylsalicylic Acid Reverses Endotoxin Tolerance in Humans In Vivo: A Randomized Placebo-Controlled Study.
    Crit Care Med. 2019;47:508-516.
    PubMed     Abstract available


    March 2019
  101. KOHOUTOVA M, Horak J, Jarkovska D, Martinkova V, et al
    Vagus Nerve Stimulation Attenuates Multiple Organ Dysfunction in Resuscitated Porcine Progressive Sepsis.
    Crit Care Med. 2019 Mar 25. doi: 10.1097/CCM.0000000000003714.
    PubMed     Abstract available


  102. BOURCIER S, Hindlet P, Guidet B, Dechartres A, et al
    Reporting of Organ Support Outcomes in Septic Shock Randomized Controlled Trials: A Methodologic Review-The Sepsis Organ Support Study.
    Crit Care Med. 2019 Mar 19. doi: 10.1097/CCM.0000000000003746.
    PubMed     Abstract available


  103. CHANG EY, Stevens ES, Bakinde N
    Sepsis in Non-ICU Patients: A Call for Guideline Reassessment.
    Crit Care Med. 2019;47:e266.
    PubMed    


  104. SKLAR MC, Dos Santos CC, Lawler PR
    Proprotein Convertase Subtilisin/Kexin Type 9 Inhibition and Survival in Sepsis: Causal Inference Through Human Genetics.
    Crit Care Med. 2019;47:489-491.
    PubMed    


  105. SIMPSON SQ
    Surveillance for Adult Sepsis Events: An Idea Whose Time Has Come.
    Crit Care Med. 2019;47:467-468.
    PubMed    


  106. RHEE C, Zhang Z, Kadri SS, Murphy DJ, et al
    Sepsis Surveillance Using Adult Sepsis Events Simplified eSOFA Criteria Versus Sepsis-3 Sequential Organ Failure Assessment Criteria.
    Crit Care Med. 2019;47:307-314.
    PubMed     Abstract available


  107. KELLY BJ, Lautenbach E, Han JH
    The authors reply.
    Crit Care Med. 2019;47:e275-e276.
    PubMed    


  108. PATNAIK R, Gurjar M
    Is Combined Biomarkers a Future Tool for Early Prediction of Mortality Among Septic Patients?
    Crit Care Med. 2019;47:e275.
    PubMed    


  109. REDFERN OC, Smith GB, Prytherch DR, Meredith P, et al
    The authors reply.
    Crit Care Med. 2019;47:e266-e267.
    PubMed    


    February 2019
  110. PEPPER DJ, Demirkale CY, Sun J, Rhee C, et al
    Does Obesity Protect Against Death in Sepsis? A Retrospective Cohort Study of 55,038 Adult Patients.
    Crit Care Med. 2019 Feb 14. doi: 10.1097/CCM.0000000000003692.
    PubMed     Abstract available


  111. KUSHIMOTO S, Abe T, Ogura H, Shiraishi A, et al
    Impact of Body Temperature Abnormalities on the Implementation of Sepsis Bundles and Outcomes in Patients With Severe Sepsis: A Retrospective Sub-Analysis of the Focused Outcome Research on Emergency Care for Acute Respiratory Distress Syndrome, Sepsi
    Crit Care Med. 2019 Feb 14. doi: 10.1097/CCM.0000000000003688.
    PubMed     Abstract available


  112. HOTCHKISS RS, Colston E, Yende S, Angus DC, et al
    Immune Checkpoint Inhibition in Sepsis: A Phase 1b Randomized, Placebo-Controlled, Single Ascending Dose Study of Antiprogrammed Cell Death-Ligand 1 (BMS-936559).
    Crit Care Med. 2019 Feb 8. doi: 10.1097/CCM.0000000000003685.
    PubMed     Abstract available


  113. ILKO SA, Vakkalanka JP, Ahmed A, Harland KK, et al
    Central Venous Access Capability and Critical Care Telemedicine Decreases Inter-Hospital Transfer Among Severe Sepsis Patients: A Mixed Methods Design.
    Crit Care Med. 2019 Feb 5. doi: 10.1097/CCM.0000000000003686.
    PubMed     Abstract available


  114. GRANJA T, Korner A, Gluck C, Hohmann JD, et al
    Targeting CD39 Toward Activated Platelets Reduces Systemic Inflammation and Improves Survival in Sepsis: A Preclinical Pilot Study.
    Crit Care Med. 2019 Feb 5. doi: 10.1097/CCM.0000000000003682.
    PubMed     Abstract available


  115. KRAFT BD, Chen L, Suliman HB, Piantadosi CA, et al
    Peripheral Blood Mononuclear Cells Demonstrate Mitochondrial Damage Clearance During Sepsis.
    Crit Care Med. 2019 Feb 5. doi: 10.1097/CCM.0000000000003681.
    PubMed     Abstract available


  116. BOSCH NA, Cohen DM, Walkey AJ
    Risk Factors for New-Onset Atrial Fibrillation in Patients With Sepsis: A Systematic Review and Meta-Analysis.
    Crit Care Med. 2019;47:280-287.
    PubMed     Abstract available


  117. DE GROOTH HJ, Girbes AR
    Corticosteroids in Sepsis: Clouded by Heterogeneity.
    Crit Care Med. 2019;47:e163-e164.
    PubMed    


  118. SCHURR JW, McLaughlin KC, Szumita PM
    Defining the Role of Corticosteroids in Sepsis: Adjunctive Therapy for Shock Reversal.
    Crit Care Med. 2019;47:e157-e158.
    PubMed    


  119. MARTIN B, Bennett TD
    Sepsis Computable Phenotypes in the Service of Observational Research.
    Crit Care Med. 2019;47:303-305.
    PubMed    


  120. OCZKOWSKI SJ, Rochwerg B, Alhazzani W, Siemieniuk RAC, et al
    The authors reply.
    Crit Care Med. 2019;47:e158-e159.
    PubMed    


  121. WOOLUM JA, Flannery AH
    The authors reply.
    Crit Care Med. 2019;47:e154.
    PubMed    


  122. OLANIPEKUN TO, Bakinde N, Effoe VS, Snyder R, et al
    Further Considerations on the Benefits of Thiamine Administration in Patients With Septic Shock.
    Crit Care Med. 2019;47:e153-e154.
    PubMed    


  123. MORELLI A, Sanfilippo F, Arnemann P, Hessler M, et al
    The Effect of Propofol and Dexmedetomidine Sedation on Norepinephrine Requirements in Septic Shock Patients: A Crossover Trial.
    Crit Care Med. 2019;47:e89-e95.
    PubMed     Abstract available


    January 2019
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    Effect of Antihypertensive Medications on Sepsis-Related Outcomes: A Population-Based Cohort Study.
    Crit Care Med. 2019 Jan 24. doi: 10.1097/CCM.0000000000003654.
    PubMed     Abstract available


  125. CARLTON EF, Kohne JG, Shankar-Hari M, Prescott HC, et al
    Readmission Diagnoses After Pediatric Severe Sepsis Hospitalization.
    Crit Care Med. 2019 Jan 22. doi: 10.1097/CCM.0000000000003646.
    PubMed     Abstract available


  126. GARDNER AK, Ghita GL, Wang Z, Ozrazgat-Baslanti T, et al
    The Development of Chronic Critical Illness Determines Physical Function, Quality of Life, and Long-Term Survival Among Early Survivors of Sepsis in Surgical ICUs.
    Crit Care Med. 2019 Jan 18. doi: 10.1097/CCM.0000000000003655.
    PubMed     Abstract available


  127. DAHABA AA
    Can We Improve Long-Term Survival of Patients With Severe Sepsis at ICU Admission?
    Crit Care Med. 2019;47:e71.
    PubMed    


  128. WALKEY AJ
    Exploring the Pathways Revealed by International Sepsis Benchmarking.
    Crit Care Med. 2019;47:135-137.
    PubMed    


  129. LANKADEVA YR, Kosaka J, Iguchi N, Evans RG, et al
    Effects of Fluid Bolus Therapy on Renal Perfusion, Oxygenation, and Function in Early Experimental Septic Kidney Injury.
    Crit Care Med. 2019;47:e36-e43.
    PubMed     Abstract available


  130. LU C, Liu Q, Yuan H, Wang L, et al
    Implementation of the Smart Use of Antibiotics Program to Reduce Unnecessary Antibiotic Use in a Neonatal ICU: A Prospective Interrupted Time-Series Study in a Developing Country.
    Crit Care Med. 2019;47:e1-e7.
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    December 2018
  131. BARBASH IJ, Davis B, Kahn JM
    National Performance on the Medicare SEP-1 Sepsis Quality Measure.
    Crit Care Med. 2018 Dec 21. doi: 10.1097/CCM.0000000000003613.
    PubMed     Abstract available


  132. KLOMPAS M, Rhee C
    Current Sepsis Mandates Are Overly Prescriptive, and Some Aspects May Be Harmful.
    Crit Care Med. 2018 Dec 4. doi: 10.1097/CCM.0000000000003579.
    PubMed    


  133. VARGAS M, Servillo G
    The End of Corticosteroid in Sepsis: Fragile Results From Fragile Trials.
    Crit Care Med. 2018;46:e1228.
    PubMed    


  134. GOODWIN AJ
    Can Serial Quick Sequential (Sepsis-Related) Organ Failure Assessment Measurement Aid in Sepsis Identification and Triage Decisions?
    Crit Care Med. 2018;46:2046-2048.
    PubMed    


  135. KEMPKER JA, Martin GS
    Severity and Timing of Onset Drive Economic Costs and Clinical Outcomes With Sepsis.
    Crit Care Med. 2018;46:2043-2044.
    PubMed    


    November 2018
  136. RHEE C, Jentzsch MS, Kadri SS, Seymour CW, et al
    Variation in Identifying Sepsis and Organ Dysfunction Using Administrative Versus Electronic Clinical Data and Impact on Hospital Outcome Comparisons.
    Crit Care Med. 2018 Nov 13. doi: 10.1097/CCM.0000000000003554.
    PubMed     Abstract available


  137. MEHTA NM
    Nutritional Status and Outcomes in Pediatric Severe Sepsis-Size Matters.
    Crit Care Med. 2018;46:1886-1887.
    PubMed    


  138. CARLTON EF, Prescott HC
    Variation in Sepsis-Related Mortality; Implications for Performance Improvement.
    Crit Care Med. 2018;46:1871-1873.
    PubMed    


  139. WALLEY KR, Boyd JH, Kong HJ, Russell JA, et al
    Low Low-Density Lipoprotein Levels Are Associated With, But Do Not Causally Contribute to, Increased Mortality in Sepsis.
    Crit Care Med. 2018 Nov 1. doi: 10.1097/CCM.0000000000003551.
    PubMed     Abstract available


    October 2018
  140. LINDELL RB, Nishisaki A, Weiss SL, Balamuth F, et al
    Comparison of Methods for Identification of Pediatric Severe Sepsis and Septic Shock in the Virtual Pediatric Systems Database.
    Crit Care Med. 2018 Oct 31. doi: 10.1097/CCM.0000000000003541.
    PubMed     Abstract available


  141. CHUNG KP, Chen GY, Chuang TY, Huang YT, et al
    Increased Plasma Acetylcarnitine in Sepsis Is Associated With Multiple Organ Dysfunction and Mortality: A Multicenter Cohort Study.
    Crit Care Med. 2018 Oct 30. doi: 10.1097/CCM.0000000000003517.
    PubMed     Abstract available


  142. LAI CC, Wang YH, Wang CY, Wang HC, et al
    Risk of Sepsis and Mortality Among Patients With Chronic Obstructive Pulmonary Disease Treated With Angiotensin-Converting Enzyme Inhibitors or Angiotensin Receptor Blockers.
    Crit Care Med. 2018 Oct 9. doi: 10.1097/CCM.0000000000003475.
    PubMed     Abstract available


  143. SRINIVASAN V
    Probiotics in Pediatric Severe Sepsis: The Time Has Come to Trust Our 'Gut'!
    Crit Care Med. 2018;46:1707-1708.
    PubMed    


  144. MARIK PE, Farkas JD
    The Changing Paradigm of Sepsis: Early Diagnosis, Early Antibiotics, Early Pressors, and Early Adjuvant Treatment.
    Crit Care Med. 2018;46:1690-1692.
    PubMed    


  145. KANJILAL S, Kalil AC, Klompas M
    What Is the Best Treatment for Vancomycin-Resistant Enterococcal Bloodstream Infections?
    Crit Care Med. 2018;46:1700-1703.
    PubMed    


    September 2018
  146. RANZANI OT, Shankar-Hari M, Harrison DA, Rabello LS, et al
    A Comparison of Mortality From Sepsis in Brazil and England: The Impact of Heterogeneity in General and Sepsis-Specific Patient Characteristics.
    Crit Care Med. 2018 Sep 20. doi: 10.1097/CCM.0000000000003438.
    PubMed     Abstract available


  147. HASSLACHER J, Joannidis M
    Secretoneurin in Sepsis: Is It the Brain?
    Crit Care Med. 2018;46:e959.
    PubMed    


  148. CLAXTON AJ, Thompson-Leduc P, Kirson NY, Rice B, et al
    Efficacy and Safety of Procalcitonin Guidance in Patients With Suspected or Confirmed Sepsis: A Systematic Review and Meta-Analysis: Author Correction.
    Crit Care Med. 2018;46:1560.
    PubMed    


  149. EVANS LE
    Progress Toward "Ruling Out" Sepsis.
    Crit Care Med. 2018;46:1553-1554.
    PubMed    


  150. LEWIS AJ, Lee JS, Rosengart MR
    Translational Sepsis Research: Spanning the Divide.
    Crit Care Med. 2018;46:1497-1505.
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    August 2018
  151. REDFERN OC, Smith GB, Prytherch DR, Meredith P, et al
    A Comparison of the Quick Sequential (Sepsis-Related) Organ Failure Assessment Score and the National Early Warning Score in Non-ICU Patients With/Without Infection.
    Crit Care Med. 2018 Aug 20. doi: 10.1097/CCM.0000000000003359.
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  152. KIEVLAN DR, Zhang LA, Chang CH, Angus DC, et al
    Evaluation of Repeated Quick Sepsis-Related Organ Failure Assessment Measurements Among Patients With Suspected Infection.
    Crit Care Med. 2018 Aug 20. doi: 10.1097/CCM.0000000000003360.
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  153. KIDSON KM, Henderson WR, Hutcheon JA
    Case Fatality and Adverse Outcomes Are Reduced in Pregnant Women With Severe Sepsis or Septic Shock Compared With Age-Matched Comorbid-Matched Nonpregnant Women.
    Crit Care Med. 2018 Aug 9. doi: 10.1097/CCM.0000000000003348.
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  154. IRVING SY, Daly B, Verger J, Typpo KV, et al
    The Association of Nutrition Status Expressed as Body Mass Index z Score With Outcomes in Children With Severe Sepsis: A Secondary Analysis From the Sepsis Prevalence, Outcomes, and Therapies (SPROUT) Study.
    Crit Care Med. 2018 Aug 7. doi: 10.1097/CCM.0000000000003351.
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  155. HANIFFA R, Beane A, Dondorp AM
    Is the Tail Wagging the Dog in Sepsis?
    Crit Care Med. 2018;46:e818.
    PubMed    


  156. PANNU S, Crouser ED
    Blue Light Illuminates a Novel Sepsis Treatment.
    Crit Care Med. 2018;46:1381-1382.
    PubMed    


  157. SIMPSON SQ
    Sepsis-The "Gift" That Keeps on Giving, Regardless of Age.
    Crit Care Med. 2018;46:1378-1380.
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  158. GAUGHAN J
    Sepsis Redefined...Again.
    Crit Care Med. 2018;46:1378.
    PubMed    


    July 2018
  159. PAOLI CJ, Reynolds MA, Sinha M, Gitlin M, et al
    Epidemiology and Costs of Sepsis in the United States-An Analysis Based on Timing of Diagnosis and Severity Level.
    Crit Care Med. 2018 Jul 25. doi: 10.1097/CCM.0000000000003342.
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  160. HATFIELD KM, Dantes RB, Baggs J, Sapiano MRP, et al
    Assessing Variability in Hospital-Level Mortality Among U.S. Medicare Beneficiaries With Hospitalizations for Severe Sepsis and Septic Shock.
    Crit Care Med. 2018 Jul 17. doi: 10.1097/CCM.0000000000003324.
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  161. WU J, Han B, Fanelli V, Wen X, et al
    Distinctive Roles and Mechanisms of Human Neutrophil Peptides in Experimental Sepsis and Acute Respiratory Distress Syndrome.
    Crit Care Med. 2018 Jul 2. doi: 10.1097/CCM.0000000000003265.
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  162. ROCHWERG B, Oczkowski SJ, Siemieniuk RAC, Agoritsas T, et al
    Corticosteroids in Sepsis: An Updated Systematic Review and Meta-Analysis.
    Crit Care Med. 2018 Jul 2. doi: 10.1097/CCM.0000000000003262.
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  163. THAMM K, Schrimpf C, Retzlaff J, Idowu TO, et al
    Molecular Regulation of Acute Tie2 Suppression in Sepsis.
    Crit Care Med. 2018 Jul 2. doi: 10.1097/CCM.0000000000003269.
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  164. AKYOL BEYOGLU C, Koksal GM, Esquinas AM
    Association Between PaCO2 and Survival to Hospital Discharge Among Patients Diagnosed With Sepsis in the Emergency Department-Is PaCO2 a Predictive Parameter for Hospital Discharge?
    Crit Care Med. 2018;46:e718.
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  165. GERLACH AT
    Sepsis Biomarkers...The Long and Winding Road.
    Crit Care Med. 2018;46:1194-1195.
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  166. KELLY BJ, Lautenbach E, Nachamkin I, Coffin SE, et al
    Combined Biomarkers Predict Acute Mortality Among Critically Ill Patients With Suspected Sepsis.
    Crit Care Med. 2018;46:1106-1113.
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    June 2018
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    Compliance With the National SEP-1 Quality Measure and Association With Sepsis Outcomes: A Multicenter Retrospective Cohort Study.
    Crit Care Med. 2018 Jun 28. doi: 10.1097/CCM.0000000000003261.
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  168. COOPERSMITH CM, De Backer D, Deutschman CS, Ferrer R, et al
    Surviving Sepsis Campaign: Research Priorities for Sepsis and Septic Shock.
    Crit Care Med. 2018 Jun 27. doi: 10.1097/CCM.0000000000003225.
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  169. ANGURANA SK, Bansal A, Singhi S, Aggarwal R, et al
    Evaluation of Effect of Probiotics on Cytokine Levels in Critically Ill Children With Severe Sepsis: A Double-Blind, Placebo-Controlled Trial.
    Crit Care Med. 2018 Jun 27. doi: 10.1097/CCM.0000000000003279.
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  170. CHUANG YC, Lin HY, Chen PY, Lin CY, et al
    Survival of Patients With Vancomycin-Resistant Enterococcus faecium Bacteremia Treated With Conventional or High Doses of Daptomycin or Linezolid Is Associated With the Rate of Bacterial Clearance.
    Crit Care Med. 2018 Jun 27. doi: 10.1097/CCM.0000000000003264.
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  171. LEVY MM, Evans LE, Rhodes A
    The Surviving Sepsis Campaign Bundle: 2018 Update.
    Crit Care Med. 2018;46:997-1000.
    PubMed    


  172. JACOBS MC, Wiersinga WJ
    Interleukin-34: A New Player in the Sepsis Arena.
    Crit Care Med. 2018;46:1032-1033.
    PubMed    


  173. PROWLE JR
    Renal Blood Flow Measurement in Early Clinical Sepsis-Can You Catch a Shadow?
    Crit Care Med. 2018;46:1028-1030.
    PubMed    


  174. SHANKAR-HARI M, Rubenfeld GD
    Race, Ethnicity, and Sepsis: Beyond Adjusted Odds Ratios.
    Crit Care Med. 2018;46:1009-1010.
    PubMed    


  175. HENSLEY MK, Prescott HC
    Bad Brains, Bad Outcomes: Acute Neurologic Dysfunction and Late Death After Sepsis.
    Crit Care Med. 2018;46:1001-1002.
    PubMed    


    May 2018
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    Inhibition of Vascular Endothelial Cell Leak Following Escherichia coli Attachment in an Experimental Model of Sepsis.
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  177. LIMA A, van Rooij T, Ergin B, Sorelli M, et al
    Dynamic Contrast-Enhanced Ultrasound Identifies Microcirculatory Alterations in Sepsis-Induced Acute Kidney Injury.
    Crit Care Med. 2018 May 15. doi: 10.1097/CCM.0000000000003209.
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  178. ESTENSSORO E, Kanoore Edul VS, Loudet CI, Osatnik J, et al
    Predictive Validity of Sepsis-3 Definitions and Sepsis Outcomes in Critically Ill Patients: A Cohort Study in 49 ICUs in Argentina.
    Crit Care Med. 2018 May 8. doi: 10.1097/CCM.0000000000003208.
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  179. MEARELLI F, Fiotti N, Giansante C, Casarsa C, et al
    Derivation and Validation of a Biomarker-Based Clinical Algorithm to Rule Out Sepsis From Noninfectious Systemic Inflammatory Response Syndrome at Emergency Department Admission: A Multicenter Prospective Study.
    Crit Care Med. 2018 May 7. doi: 10.1097/CCM.0000000000003206.
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  180. ABU-KAF H, Mizrakli Y, Novack V, Dreiher J, et al
    Long-Term Survival of Young Patients Surviving ICU Admission With Severe Sepsis.
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  181. LEWIS AJ, Zhang X, Griepentrog JE, Yuan D, et al
    Blue Light Enhances Bacterial Clearance and Reduces Organ Injury During Sepsis.
    Crit Care Med. 2018 May 4. doi: 10.1097/CCM.0000000000003190.
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  182. KALIL AC, Van Schooneveld TC
    Is Procalcitonin-Guided Therapy Associated With Beneficial Outcomes in Critically Ill Patients With Sepsis?
    Crit Care Med. 2018;46:811-812.
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  183. STAUNTON O, Staunton C
    The Urgency of Now: Attacking the Sepsis Crisis.
    Crit Care Med. 2018;46:809-810.
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    April 2018
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    Sex-Mediated Response to the Beta-Blocker Landiolol in Sepsis: An Experimental, Randomized Study.
    Crit Care Med. 2018 Apr 7. doi: 10.1097/CCM.0000000000003146.
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  185. MASSE MH, Richard MA, D'Aragon F, St-Arnaud C, et al
    Early Evidence of Sepsis-Associated Hyperperfusion-A Study of Cerebral Blood Flow Measured With MRI Arterial Spin Labeling in Critically Ill Septic Patients and Control Subjects.
    Crit Care Med. 2018 Apr 6. doi: 10.1097/CCM.0000000000003147.
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    Comparative Usefulness of Sepsis-3, Burn Sepsis, and Conventional Sepsis Criteria in Patients With Major Burns.
    Crit Care Med. 2018 Apr 3. doi: 10.1097/CCM.0000000000003144.
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  187. CROUSER ED
    Sepsis-Induced Renal Failure: Ischemia or Toxemia?
    Crit Care Med. 2018;46:658-660.
    PubMed    


  188. KLOMPAS M, Rhee C
    Missed Opportunities for Better Sepsis Care or Misplaced Blame? Deconstructing Patients' Encounters in the Week Before Sepsis Hospitalizations.
    Crit Care Med. 2018;46:644-645.
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  189. NATHANSON BH
    First, Most, and Best: The Implications of Delays in Implementing Surviving Sepsis Campaign Guidelines.
    Crit Care Med. 2018;46:642-643.
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  190. SAVEL RH, Shiloh AL, Simon RJ, Kupfer Y, et al
    Using Big Data to See the Big Picture in Sepsis.
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    March 2018
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    Dynamics of Endotoxin, Inflammatory Variables, and Organ Dysfunction After Treatment With Antibiotics in an Escherichia coli Porcine Intensive Care Sepsis Model.
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    Unsupervised Analysis of Transcriptomics in Bacterial Sepsis Across Multiple Datasets Reveals Three Robust Clusters.
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    Nationwide Trend of Sepsis: A Comparison Among Octogenarians, Elderly, and Young Adults.
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  194. SCHEER CS, Kuhn SO, Rehberg S
    Sepsis-3 Is a Positive Evolution in Discrimination Between Septic and Nonseptic Patients As Well As Sepsis Entities, Not a Step Backward.
    Crit Care Med. 2018;46:e273.
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  195. MACHADO FR, Azevedo LCP
    Sepsis: A Threat That Needs a Global Solution.
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    Temporal Trends in Incidence, Sepsis-Related Mortality, and Hospital-Based Acute Care After Sepsis.
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    February 2018
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    Prognostic Value of Secretoneurin in Patients With Severe Sepsis and Septic Shock: Data From the Albumin Italian Outcome Sepsis Study.
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    Racial Differences in Sepsis Mortality at U.S. Academic Medical Center-Affiliated Hospitals.
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    The Impact of Acute Organ Dysfunction on Long-Term Survival in Sepsis.
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    Lactate Level Versus Lactate Clearance for Predicting Mortality in Patients With Septic Shock Defined by Sepsis-3.
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    Reporting of Sepsis Cases for Performance Measurement Versus for Reimbursement in New York State.
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    Early Fluid Management in Sepsis: Yes.
    Crit Care Med. 2018;46:327-328.
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    January 2018
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    Interleukin-34 Ameliorates Survival and Bacterial Clearance in Polymicrobial Sepsis.
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    Urgent Chemotherapy in Sepsis-Like Shock Related to Hematologic Malignancies.
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    Sepsis-Associated Coagulopathy Severity Predicts Hospital Mortality.
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    Development and External Validation of an Automated Computer-Aided Risk Score for Predicting Sepsis in Emergency Medical Admissions Using the Patient's First Electronically Recorded Vital Signs and Blood Test Results.
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    Prompt Administration of Antibiotics and Fluids in the Treatment of Sepsis: A Murine Trial.
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    Decrease in Histidine-Rich Glycoprotein as a Novel Biomarker to Predict Sepsis Among Systemic Inflammatory Response Syndrome.
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    A Comparative Analysis of Sepsis Identification Methods in an Electronic Database.
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    Delay Within the 3-Hour Surviving Sepsis Campaign Guideline on Mortality for Patients With Severe Sepsis and Septic Shock.
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  212. DOTSON B
    Calcium Channel Blockers and Sepsis Outcomes.
    Crit Care Med. 2018;46:e97-e98.
    PubMed    


  213. DELMAS B, Jabot J, Chanareille P, Ferdynus C, et al
    Leptospirosis in ICU: A Retrospective Study of 134 Consecutive Admissions.
    Crit Care Med. 2018;46:93-99.
    PubMed     Abstract available


  214. LANKADEVA YR, Kosaka J, Evans RG, Bellomo R, et al
    Urinary Oxygenation as a Surrogate Measure of Medullary Oxygenation During Angiotensin II Therapy in Septic Acute Kidney Injury.
    Crit Care Med. 2018;46:e41-e48.
    PubMed     Abstract available


  215. TYLER PD, Stone DJ, Geisler BP, McLennan S, et al
    Racial and Geographic Disparities in Interhospital ICU Transfers.
    Crit Care Med. 2018;46:e76-e80.
    PubMed     Abstract available


  216. MIANO TA, Lam S
    The Healthy User Effect in Studies of Statins in the Critically Ill.
    Crit Care Med. 2018;46:e95.
    PubMed    


  217. KRAMER AA
    A Self-Fulfilling Hypothesis.
    Crit Care Med. 2018;46:158-159.
    PubMed    


    December 2017
  218. NEMATI S, Holder A, Razmi F, Stanley MD, et al
    An Interpretable Machine Learning Model for Accurate Prediction of Sepsis in the ICU.
    Crit Care Med. 2017 Dec 26. doi: 10.1097/CCM.0000000000002936.
    PubMed     Abstract available


  219. IANKOVA I, Thompson-Leduc P, Kirson NY, Rice B, et al
    Efficacy and Safety of Procalcitonin Guidance in Patients With Suspected or Confirmed Sepsis: A Systematic Review and Meta-Analysis.
    Crit Care Med. 2017 Dec 21. doi: 10.1097/CCM.0000000000002928.
    PubMed     Abstract available


  220. SEMERARO F, Colucci M, Caironi P, Masson S, et al
    Platelet Drop and Fibrinolytic Shutdown in Patients With Sepsis.
    Crit Care Med. 2017 Dec 19. doi: 10.1097/CCM.0000000000002919.
    PubMed     Abstract available


  221. ROBERTS BW, Mohr NM, Ablordeppey E, Drewry AM, et al
    Association Between Partial Pressure of Arterial Carbon Dioxide and Survival to Hospital Discharge Among Patients Diagnosed With Sepsis in the Emergency Department.
    Crit Care Med. 2017 Dec 19. doi: 10.1097/CCM.0000000000002918.
    PubMed     Abstract available


  222. VALLEY TS, Nallamothu BK, Heung M, Iwashyna TJ, et al
    Hospital Variation in Renal Replacement Therapy for Sepsis in the United States.
    Crit Care Med. 2017 Dec 4. doi: 10.1097/CCM.0000000000002878.
    PubMed     Abstract available


  223. PHILLIPS GS, Osborn TM, Terry KM, Gesten F, et al
    The New York Sepsis Severity Score: Development of a Risk-Adjusted Severity Model for Sepsis.
    Crit Care Med. 2017 Dec 4. doi: 10.1097/CCM.0000000000002824.
    PubMed     Abstract available


  224. KIKUTANI K, Ohshimo S, Shime N
    Potential Confounders of Procalcitonin-Guided Antibiotic Therapy for Sepsis.
    Crit Care Med. 2017;45:e1310-e1311.
    PubMed    


  225. KRAMER AH
    Is A Hemoglobin Concentration As Low As 7 g/dL Adequate For All Critically Ill Patients With Sepsis? Legitimate Doubts Remain!
    Crit Care Med. 2017;45:2101-2102.
    PubMed    


  226. ERWIN BL, Denaburg MA, Barker AB, McArdle PJ, et al
    Evaluation of Vasopressin for Septic Shock in Patients on Chronic Renin-Angiotensin-Aldosterone System Inhibitors.
    Crit Care Med. 2017;45:e1226-e1232.
    PubMed     Abstract available


  227. DU W, Liu D, Long Y, Wang X, et al
    The beta-Blocker Esmolol Restores the Vascular Waterfall Phenomenon After Acute Endotoxemia.
    Crit Care Med. 2017;45:e1247-e1253.
    PubMed     Abstract available


  228. JAMME M, Daviaud F, Charpentier J, Marin N, et al
    Time Course of Septic Shock in Immunocompromised and Nonimmunocompromised Patients.
    Crit Care Med. 2017;45:2031-2039.
    PubMed     Abstract available


  229. DUPUIS C, Garrouste-Orgeas M, Bailly S, Adrie C, et al
    Effect of Transfusion on Mortality and Other Adverse Events Among Critically Ill Septic Patients: An Observational Study Using a Marginal Structural Cox Model.
    Crit Care Med. 2017;45:1972-1980.
    PubMed     Abstract available


    November 2017
  230. LEISMAN DE, Doerfler ME, Schneider SM, Masick KD, et al
    Predictors, Prevalence, and Outcomes of Early Crystalloid Responsiveness Among Initially Hypotensive Patients With Sepsis and Septic Shock.
    Crit Care Med. 2017 Nov 3. doi: 10.1097/CCM.0000000000002834.
    PubMed     Abstract available


  231. CASEY JD, Semler MW, Bastarache JA
    Aspirin for Sepsis Prophylaxis: An Ounce of Prevention?
    Crit Care Med. 2017;45:1959-1960.
    PubMed    


  232. JAWA RS, Kew RR
    Sepsis in the Critically Ill-Does Gender Matter?
    Crit Care Med. 2017;45:1957-1959.
    PubMed    


  233. SPOLARICS Z
    Victims or Culprits, B Cells May Serve as Markers for Mortality Risk and Targeted Therapy in Sepsis.
    Crit Care Med. 2017;45:1951-1952.
    PubMed    


  234. LIU VX, Walkey AJ
    Machine Learning and Sepsis: On the Road to Revolution.
    Crit Care Med. 2017;45:1946-1947.
    PubMed    


  235. COQUEREL D, Chagnon F, Sainsily X, Dumont L, et al
    ELABELA Improves Cardio-Renal Outcome in Fatal Experimental Septic Shock.
    Crit Care Med. 2017;45:e1139-e1148.
    PubMed     Abstract available


  236. MOSKOWITZ A, Patel PV, Grossestreuer AV, Chase M, et al
    Quick Sequential Organ Failure Assessment and Systemic Inflammatory Response Syndrome Criteria as Predictors of Critical Care Intervention Among Patients With Suspected Infection.
    Crit Care Med. 2017;45:1813-1819.
    PubMed     Abstract available


    October 2017
  237. STEELAND S, Van Ryckeghem S, Vandewalle J, Ballegeer M, et al
    Simultaneous Inhibition of Tumor Necrosis Factor Receptor 1 and Matrix Metalloproteinase 8 Completely Protects Against Acute Inflammation and Sepsis.
    Crit Care Med. 2017 Oct 31. doi: 10.1097/CCM.0000000000002813.
    PubMed     Abstract available


  238. RUSH B, Tyler PD, Stone DJ, Geisler BP, et al
    Outcomes of Ventilated Patients With Sepsis Who Undergo Interhospital Transfer: A Nationwide Linked Analysis.
    Crit Care Med. 2017 Oct 24. doi: 10.1097/CCM.0000000000002777.
    PubMed     Abstract available


  239. YEHYA N, Wong HR
    Adaptation of a Biomarker-Based Sepsis Mortality Risk Stratification Tool for Pediatric Acute Respiratory Distress Syndrome.
    Crit Care Med. 2017 Oct 6. doi: 10.1097/CCM.0000000000002754.
    PubMed     Abstract available


  240. PUTHUCHEARY ZA, Sun Y, Zeng K, Vu LH, et al
    Sepsis Reduces Bone Strength Before Morphologic Changes Are Identifiable.
    Crit Care Med. 2017 Oct 6. doi: 10.1097/CCM.0000000000002732.
    PubMed     Abstract available


  241. WONG HR, Sweeney TE, Hart KW, Khatri P, et al
    Pediatric Sepsis Endotypes Among Adults With Sepsis.
    Crit Care Med. 2017 Oct 6. doi: 10.1097/CCM.0000000000002733.
    PubMed     Abstract available


  242. EHLENBACH WJ, Gilmore-Bykovskyi A, Repplinger MD, Westergaard RP, et al
    Sepsis Survivors Admitted to Skilled Nursing Facilities: Cognitive Impairment, Activities of Daily Living Dependence, and Survival.
    Crit Care Med. 2017 Oct 6. doi: 10.1097/CCM.0000000000002755.
    PubMed     Abstract available


  243. MEYER NJ, Reilly JP, Anderson BJ, Palakshappa JA, et al
    Mortality Benefit of Recombinant Human Interleukin-1 Receptor Antagonist for Sepsis Varies by Initial Interleukin-1 Receptor Antagonist Plasma Concentration.
    Crit Care Med. 2017 Oct 6. doi: 10.1097/CCM.0000000000002749.
    PubMed     Abstract available


  244. VITORIO D, Nassar AP Jr, Caruso P
    Procalcitonin Clearance and Prognosis in Sepsis: Are There Really an Optimal Cutoff and Time Interval?
    Crit Care Med. 2017;45:e1097-e1098.
    PubMed    


  245. PFORTMUELLER CA, Meisel C, Schefold JC
    Interpreting Immune Mediator Dysbalance in Sepsis.
    Crit Care Med. 2017;45:e1094-e1095.
    PubMed    


  246. RIMAWI RH
    Bad Response or Bad Luck? A New Versus Recrudescent Sepsis Readmission.
    Crit Care Med. 2017;45:1788-1789.
    PubMed    


  247. LANSPA MJ, Morris AH
    The Importance of Clinical Context on Assessing Outcomes in Sepsis.
    Crit Care Med. 2017;45:1783-1785.
    PubMed    


  248. NUGENT KL, Coopersmith CM
    Fluid Management in Sepsis-Is There a Golden Hour (or Two)?
    Crit Care Med. 2017;45:1773-1775.
    PubMed    


  249. GRASSELLI G, Scaravilli V, Di Bella S, Biffi S, et al
    Nosocomial Infections During Extracorporeal Membrane Oxygenation: Incidence, Etiology, and Impact on Patients' Outcome.
    Crit Care Med. 2017;45:1726-1733.
    PubMed     Abstract available


    September 2017
  250. ANNANE D, Pastores SM, Rochwerg B, Arlt W, et al
    Guidelines for the Diagnosis and Management of Critical Illness-Related Corticosteroid Insufficiency (CIRCI) in Critically Ill Patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017.
    Crit Care Med. 2017 Sep 21. doi: 10.1097/CCM.0000000000002737.
    PubMed     Abstract available


  251. JONES JM, Fingar KR, Miller MA, Coffey R, et al
    Racial Disparities in Sepsis-Related In-Hospital Mortality: Using a Broad Case Capture Method and Multivariate Controls for Clinical and Hospital Variables, 2004-2013.
    Crit Care Med. 2017 Sep 12. doi: 10.1097/CCM.0000000000002699.
    PubMed     Abstract available


  252. WANG HE, Jones AR, Donnelly JP
    Revised National Estimates of Emergency Department Visits for Sepsis in the United States.
    Crit Care Med. 2017;45:1443-1449.
    PubMed     Abstract available


  253. AGAROSSI A, Pintaudi G
    Antimicrobials and Progression to Septic Shock in Severe Sepsis Patients: Is Delay the Only Thing That Matters?
    Crit Care Med. 2017;45:e988-e989.
    PubMed    


  254. MARSHALL JC
    Steroids Redux: Targeting the Mineralocorticoid Axis in Sepsis.
    Crit Care Med. 2017;45:1582-1583.
    PubMed    


  255. GAUDILLIERE B, Angst MS, Hotchkiss RS
    Deep Immune Profiling in Trauma and Sepsis: Flow Is the Way to Go!
    Crit Care Med. 2017;45:1577-1578.
    PubMed    


  256. RHEE C, Klompas M
    What Is the National Burden of Sepsis in U.S. Emergency Departments? It Depends on the Definition.
    Crit Care Med. 2017;45:1569-1571.
    PubMed    


  257. DEUTSCHMAN CS
    Sepsis-3: Seeing the Entire Picture.
    Crit Care Med. 2017;45:1567-1569.
    PubMed    


  258. SPRUNG CL, Trahtemberg U
    What Definition Should We Use for Sepsis and Septic Shock?
    Crit Care Med. 2017;45:1564-1567.
    PubMed    


  259. FADEL F, Andre-Gregoire G, Gravez B, Bauvois B, et al
    Aldosterone and Vascular Mineralocorticoid Receptors in Murine Endotoxic and Human Septic Shock.
    Crit Care Med. 2017;45:e954-e962.
    PubMed     Abstract available


    August 2017
  260. VAN VUGHT LA, Scicluna BP, Wiewel MA, Hoogendijk AJ, et al
    Association of Gender With Outcome and Host Response in Critically Ill Sepsis Patients.
    Crit Care Med. 2017 Aug 11. doi: 10.1097/CCM.0000000000002649.
    PubMed     Abstract available


  261. ZHAI Q, Lai D, Cui P, Zhou R, et al
    Selective Activation of Basal Forebrain Cholinergic Neurons Attenuates Polymicrobial Sepsis-Induced Inflammation via the Cholinergic Anti-Inflammatory Pathway.
    Crit Care Med. 2017 Aug 10. doi: 10.1097/CCM.0000000000002646.
    PubMed     Abstract available


  262. TRAUER J, Muhi S, McBryde ES, Al Harbi SA, et al
    Quantifying the Effects of Prior Acetyl-Salicylic Acid on Sepsis-Related Deaths: An Individual Patient Data Meta-Analysis Using Propensity Matching.
    Crit Care Med. 2017 Aug 9. doi: 10.1097/CCM.0000000000002654.
    PubMed     Abstract available


  263. KALIL AC, Kellum JA
    Is Early Goal-Directed Therapy Harmful to Patients With Sepsis and High Disease Severity?
    Crit Care Med. 2017;45:1265-1267.
    PubMed    


    July 2017
  264. SHANKAR-HARI M, Singer M, Spencer J
    Can Concurrent Abnormalities in Free Light Chains and Immunoglobulin Concentrations Identify a Target Population for Immunoglobulin Trials in Sepsis?
    Crit Care Med. 2017 Jul 22. doi: 10.1097/CCM.0000000000002627.
    PubMed     Abstract available


  265. DEMERLE KM, Royer SC, Mikkelsen ME, Prescott HC, et al
    Readmissions for Recurrent Sepsis: New or Relapsed Infection?
    Crit Care Med. 2017 Jul 22. doi: 10.1097/CCM.0000000000002626.
    PubMed     Abstract available


  266. VAN VUGHT LA, Holman R, de Jonge E, de Keizer NF, et al
    Diabetes Is Not Associated With Increased 90-Day Mortality Risk in Critically Ill Patients With Sepsis.
    Crit Care Med. 2017 Jul 21. doi: 10.1097/CCM.0000000000002590.
    PubMed     Abstract available


  267. CHURPEK MM, Snyder A, Sokol S, Pettit NN, et al
    Investigating the Impact of Different Suspicion of Infection Criteria on the Accuracy of Quick Sepsis-Related Organ Failure Assessment, Systemic Inflammatory Response Syndrome, and Early Warning Scores.
    Crit Care Med. 2017 Jul 21. doi: 10.1097/CCM.0000000000002648.
    PubMed     Abstract available


  268. MACHADO FR, Ferreira EM, Sousa JL, Silva C, et al
    Quality Improvement Initiatives in Sepsis in an Emerging Country: Does the Institution's Main Source of Income Influence the Results? An Analysis of 21,103 Patients.
    Crit Care Med. 2017 Jul 6. doi: 10.1097/CCM.0000000000002585.
    PubMed     Abstract available


  269. NI CHEALLAIGH C, Sheedy FJ
    Shields Up-Systemic Protection Provided by microRNA-21 During Sepsis?
    Crit Care Med. 2017;45:1261-1263.
    PubMed    


  270. MARRARO GA, Genovese U, Spada C, Piga MA, et al
    Can the Treatment Approach of Sepsis With Balanced Crystalloid Fluids Translate Into Therapy for Acute Respiratory Distress Syndrome if Considered as "Lung-Limited Sepsis"?
    Crit Care Med. 2017;45:1246-1248.
    PubMed    


  271. PRESCOTT HC, Donnelly JP
    Penalizing Readmissions After Sepsis Could Do More Harm Than Good.
    Crit Care Med. 2017;45:1243-1244.
    PubMed    


    June 2017
  272. LEISMAN DE, Goldman C, Doerfler ME, Masick KD, et al
    Patterns and Outcomes Associated With Timeliness of Initial Crystalloid Resuscitation in a Prospective Sepsis and Septic Shock Cohort.
    Crit Care Med. 2017 Jun 30. doi: 10.1097/CCM.0000000000002574.
    PubMed     Abstract available


  273. LEE CC, Lee MG, Lee WC, Lai CC, et al
    Preadmission Use of Calcium Channel Blocking Agents Is Associated With Improved Outcomes in Patients With Sepsis: A Population-Based Propensity Score-Matched Cohort Study.
    Crit Care Med. 2017 Jun 27. doi: 10.1097/CCM.0000000000002550.
    PubMed     Abstract available


  274. HE X, Su F, Xie K, Taccone FS, et al
    Should Hyperoxia Be Avoided During Sepsis? An Experimental Study in Ovine Peritonitis.
    Crit Care Med. 2017 Jun 14. doi: 10.1097/CCM.0000000000002524.
    PubMed     Abstract available


  275. LEISMAN DE, Sethna CB
    Renin-Angiotensin-Aldosterone System Blockade Use in Sepsis Patients: Did It Impact Renal Outcomes?
    Crit Care Med. 2017;45:e624.
    PubMed    


  276. GAINES S, Alverdy JC
    Fecal Micobiota Transplantation to Treat Sepsis of Unclear Etiology.
    Crit Care Med. 2017;45:1106-1107.
    PubMed    


  277. FRAIMOW HS
    Safe at First, But Not Reaching Second: Implications of Delayed Second Doses of Antimicrobials in Patients Presenting to Emergency Departments With Sepsis.
    Crit Care Med. 2017;45:1097-1098.
    PubMed    


  278. DAVIS AL, Carcillo JA, Aneja RK, Deymann AJ, et al
    American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock.
    Crit Care Med. 2017;45:1061-1093.
    PubMed     Abstract available


  279. PELTAN ID, Mitchell KH, Rudd KE, Mann BA, et al
    Physician Variation in Time to Antimicrobial Treatment for Septic Patients Presenting to the Emergency Department.
    Crit Care Med. 2017;45:1011-1018.
    PubMed     Abstract available


  280. HENNING DJ, Carey JR, Oedorf K, Day DE, et al
    The Absence of Fever Is Associated With Higher Mortality and Decreased Antibiotic and IV Fluid Administration in Emergency Department Patients With Suspected Septic Shock.
    Crit Care Med. 2017;45:e575-e582.
    PubMed     Abstract available


  281. RUSSELL JA, Lee T, Singer J, Boyd JH, et al
    The Septic Shock 3.0 Definition and Trials: A Vasopressin and Septic Shock Trial Experience.
    Crit Care Med. 2017;45:940-948.
    PubMed     Abstract available


  282. TERRASINI N, Lionetti V
    Exosomes in Critical Illness.
    Crit Care Med. 2017;45:1054-1060.
    PubMed     Abstract available


    May 2017
  283. STERLING SA, Puskarich MA, Glass AF, Guirgis F, et al
    The Impact of the Sepsis-3 Septic Shock Definition on Previously Defined Septic Shock Patients.
    Crit Care Med. 2017 May 24. doi: 10.1097/CCM.0000000000002512.
    PubMed     Abstract available


  284. STANA F, Vujovic M, Mayaki D, Leduc-Gaudet JP, et al
    Differential Regulation of the Autophagy and Proteasome Pathways in Skeletal Muscles in Sepsis.
    Crit Care Med. 2017 May 22. doi: 10.1097/CCM.0000000000002520.
    PubMed     Abstract available


  285. DEUTSCHMAN CS
    "Defining" Sepsis: Moving Toward Measuring the "Dysregulated Host Response".
    Crit Care Med. 2017;45:927-930.
    PubMed    


  286. MARIK PE
    Glucocorticosteroids as Adjunctive Therapy for Acute Respiratory Distress Syndrome and Sepsis? Yes, But Not as Monotherapy.
    Crit Care Med. 2017;45:910-911.
    PubMed    


  287. LEVY MM
    Antibiotics in Sepsis: The New Frontier.
    Crit Care Med. 2017;45:907-908.
    PubMed    


  288. JUNG B, Mahul M, Breilh D, Legeron R, et al
    Repeated Piperacillin-Tazobactam Plasma Concentration Measurements in Severely Obese Versus Nonobese Critically Ill Septic Patients and the Risk of Under- and Overdosing.
    Crit Care Med. 2017;45:e470-e478.
    PubMed     Abstract available


  289. BERGAMIN FS, Almeida JP, Landoni G, Galas FRBG, et al
    Liberal Versus Restrictive Transfusion Strategy in Critically Ill Oncologic Patients: The Transfusion Requirements in Critically Ill Oncologic Patients Randomized Controlled Trial.
    Crit Care Med. 2017;45:766-773.
    PubMed     Abstract available


  290. DREWRY AM, Ablordeppey EA, Murray ET, Stoll CRT, et al
    Antipyretic Therapy in Critically Ill Septic Patients: A Systematic Review and Meta-Analysis.
    Crit Care Med. 2017;45:806-813.
    PubMed     Abstract available


    April 2017
  291. NORMAN BC, Cooke CR, Ely EW, Graves JA, et al
    Sepsis-Associated 30-Day Risk-Standardized Readmissions: Analysis of a Nationwide Medicare Sample.
    Crit Care Med. 2017 Apr 29. doi: 10.1097/CCM.0000000000002476.
    PubMed     Abstract available


  292. CHANG T, Tu YK, Lee CT, Chao A, et al
    Effects of Polymyxin B Hemoperfusion on Mortality in Patients With Severe Sepsis and Septic Shock: A Systemic Review, Meta-Analysis Update, and Disease Severity Subgroup Meta-Analysis.
    Crit Care Med. 2017 Apr 25. doi: 10.1097/CCM.0000000000002362.
    PubMed     Abstract available


  293. JIA P, Wu X, Dai Y, Teng J, et al
    MicroRNA-21 Is Required for Local and Remote Ischemic Preconditioning in Multiple Organ Protection Against Sepsis.
    Crit Care Med. 2017 Apr 21. doi: 10.1097/CCM.0000000000002363.
    PubMed     Abstract available


  294. EMRATH ET, Fortenberry JD, Travers C, McCracken CE, et al
    Resuscitation With Balanced Fluids Is Associated With Improved Survival in Pediatric Severe Sepsis.
    Crit Care Med. 2017 Apr 21. doi: 10.1097/CCM.0000000000002365.
    PubMed     Abstract available


  295. ARULKUMARAN N, Sixma ML, Jentho E, Ceravola E, et al
    Sequential Analysis of a Panel of Biomarkers and Pathologic Findings in a Resuscitated Rat Model of Sepsis and Recovery.
    Crit Care Med. 2017 Apr 20. doi: 10.1097/CCM.0000000000002381.
    PubMed     Abstract available


  296. ZHOU J, Tian H, Du X, Xi X, et al
    Population-Based Epidemiology of Sepsis in a Subdistrict of Beijing.
    Crit Care Med. 2017 Apr 18. doi: 10.1097/CCM.0000000000002414.
    PubMed     Abstract available


  297. PINTO BB, Dyson A, Umbrello M, Carre JE, et al
    Improved Survival in a Long-Term Rat Model of Sepsis Is Associated With Reduced Mitochondrial Calcium Uptake Despite Increased Energetic Demand.
    Crit Care Med. 2017 Apr 13. doi: 10.1097/CCM.0000000000002448.
    PubMed     Abstract available


  298. SCICLUNA BP, van der Poll T
    Turning a New Page in Sepsis Molecular Diagnostics Necessitates Context-Specific Biomarkers.
    Crit Care Med. 2017;45:e457.
    PubMed    


  299. WALLEY KR
    New Approaches to Modifying Inotropy in Sepsis-Induced Myocardial Dysfunction.
    Crit Care Med. 2017;45:754-756.
    PubMed    


  300. SIMPSON SQ
    Surviving Transfer for Sepsis: Size Matters-Or Does It?
    Crit Care Med. 2017;45:749-750.
    PubMed    


  301. LAUPLAND KB, Niven DJ
    The Normal Abnormal Vital Sign of Sepsis.
    Crit Care Med. 2017;45:747-748.
    PubMed    


  302. DEUTSCHMAN CS
    Sepsis-3: Of Love and Bliss.
    Crit Care Med. 2017;45:739-740.
    PubMed    


  303. ALDER MN, Opoka AM, Lahni P, Hildeman DA, et al
    Olfactomedin-4 Is a Candidate Marker for a Pathogenic Neutrophil Subset in Septic Shock.
    Crit Care Med. 2017;45:e426-e432.
    PubMed     Abstract available


  304. ARVANITI K, Lathyris D, Blot S, Apostolidou-Kiouti F, et al
    Cumulative Evidence of Randomized Controlled and Observational Studies on Catheter-Related Infection Risk of Central Venous Catheter Insertion Site in ICU Patients: A Pairwise and Network Meta-Analysis.
    Crit Care Med. 2017;45:e437-e448.
    PubMed     Abstract available


    March 2017
  305. FAWZY A, Walkey AJ
    Association Between Hospital Case Volume of Sepsis, Adherence to Evidence-Based Processes of Care and Patient Outcomes.
    Crit Care Med. 2017 Mar 27. doi: 10.1097/CCM.0000000000002409.
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  306. LEISMAN D, Huang V, Zhou Q, Gribben J, et al
    Delayed Second Dose Antibiotics for Patients Admitted From the Emergency Department With Sepsis: Prevalence, Risk Factors, and Outcomes.
    Crit Care Med. 2017 Mar 21. doi: 10.1097/CCM.0000000000002377.
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  307. SHANKAR-HARI M, Fear D, Lavender P, Mare T, et al
    Activation-Associated Accelerated Apoptosis of Memory B Cells in Critically Ill Patients With Sepsis.
    Crit Care Med. 2017 Mar 14. doi: 10.1097/CCM.0000000000002380.
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  308. MOSS TJ, Calland JF, Enfield KB, Gomez-Manjarres DC, et al
    New-Onset Atrial Fibrillation in the Critically Ill.
    Crit Care Med. 2017 Mar 14. doi: 10.1097/CCM.0000000000002325.
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  309. MCKOWN AC, McGuinn EM, Ware LB, Wang L, et al
    Preadmission Oral Corticosteroids Are Associated With Reduced Risk of Acute Respiratory Distress Syndrome in Critically Ill Adults With Sepsis.
    Crit Care Med. 2017 Mar 2. doi: 10.1097/CCM.0000000000002286.
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  310. SCHUETZ P, Birkhahn R, Sherwin R, Jones AE, et al
    Serial Procalcitonin Predicts Mortality in Severe Sepsis Patients: Results From the Multicenter Procalcitonin MOnitoring SEpsis (MOSES) Study.
    Crit Care Med. 2017 Mar 2. doi: 10.1097/CCM.0000000000002321.
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  311. FRENCKEN JF, van Vught LA, Peelen LM, Ong DS, et al
    An Unbalanced Inflammatory Cytokine Response Is Not Associated With Mortality Following Sepsis: A Prospective Cohort Study.
    Crit Care Med. 2017 Mar 2. doi: 10.1097/CCM.0000000000002292.
    PubMed     Abstract available


  312. PEPPER DJ
    Adipose Tissue Measurements in Patients With Sepsis.
    Crit Care Med. 2017;45:e331.
    PubMed    


  313. KUHN SO, Meissner K, Rehberg S
    Fluid Resuscitation in Sepsis: "Get the Balance Right".
    Crit Care Med. 2017;45:555-556.
    PubMed    


  314. MOROWITZ MJ, Di Caro V, Pang D, Cummings J, et al
    Dietary Supplementation With Nonfermentable Fiber Alters the Gut Microbiota and Confers Protection in Murine Models of Sepsis.
    Crit Care Med. 2017 Mar 1. doi: 10.1097/CCM.0000000000002291.
    PubMed     Abstract available


  315. KELLUM JA, Pike F, Yealy DM, Huang DT, et al
    Relationship Between Alternative Resuscitation Strategies, Host Response and Injury Biomarkers, and Outcome in Septic Shock: Analysis of the Protocol-Based Care for Early Septic Shock Study.
    Crit Care Med. 2017;45:438-445.
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  316. MYATRA SN, Prabu NR, Divatia JV, Monnet X, et al
    The Changes in Pulse Pressure Variation or Stroke Volume Variation After a "Tidal Volume Challenge" Reliably Predict Fluid Responsiveness During Low Tidal Volume Ventilation.
    Crit Care Med. 2017;45:415-421.
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    Vitamin D Deficiency in Sepsis: "Body Humors" Imbalance or Sepsis "Epiphenomenon"?
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    Sepsis Quality Improvement Initiatives: Prepare for the Marathon, Not the Sprint.
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    Desperate Times Call for Desperate Measures: Self-Cannibalism Is Protective During Sepsis.
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    Source Control in Sepsis Urgent or Not So Fast?
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  382. LEISMAN D, D'Amore J, Gribben J, Ward M, et al
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    1406: IMPACT OF THE EMERGENCY DEPARTMENT SEPSIS SCREENING TOOL ON OUTCOMES IN PATIENTS WITH SEPSIS.
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    1390: PEROXYNITRITE DECOMPOSITION CATALYST REDUCES NOREPINEPHRINE REQUIREMENT DURING SEPSIS IN OVINE MODEL.
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    1388: ASSOCIATION OF WEEKEND ADMISSION WITH SEPSIS MORTALITY IN THE UNITED STATES.
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    1387: FLECAINIDE ATTENUATES SEPSIS-INDUCED ACUTE LUNG INJURY BY CONTROLLING INFLAMMATORY RESPONSE.
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    1380: TIME-MOTION ANALYSIS AND ECONOMIC IMPACT OF SOFA SCORE INTEGRATION INTO THE NEW SEPSIS-3 DEFINITION.
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    1379: BLUE LIGHT THERAPY MODULATES THE SYSTEMIC RESPONSE TO SEPSIS IN MICE AND HUMANS.
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    PubMed    


  419. TAYLOR B, Gunn E, Templin M, Karvestski C, et al
    1370: VOLUME ADMINISTRATION AND OUTCOMES IN OBESE PATIENTS WITH SEPSIS IN THE ERA OF PROTOCOLIZED CARE.
    Crit Care Med. 2016;44.
    PubMed    


  420. LI X, Guo L, Yuan Y, Zhan CG, et al
    1368: SYNTHETIC HDL AS AN EFFECTIVE THERAPY FOR SEPSIS.
    Crit Care Med. 2016;44.
    PubMed    


  421. CHUNG KS, Kim CY, Lee SH, Kim SK, et al
    1366: CLINICAL IMPLICATIONS OF THE PLASMA EPHA2 RECEPTOR LEVEL IN PATIENTS WITH SEPSIS.
    Crit Care Med. 2016;44.
    PubMed    


  422. TANNEHILL D, Sharpe B, Miller M, Saifo A, et al
    1365: SEPSIS-3 APPLIED TO A HISTORICAL COHORT OF SEVERE SEPSIS PATIENTS TREATED OUTSIDE THE ICU.
    Crit Care Med. 2016;44.
    PubMed    


  423. GASPERINO J, Gabriel-Jocson E, Perez E, Levy R, et al
    1364: COMPARISON OF THE QSOFA SCORE AND SIRS CRITERIA IN PATIENTS WITH KNOWN OR SUSPECTED SEPSIS.
    Crit Care Med. 2016;44.
    PubMed    


  424. ZHAI X, Jiang L, Yang Z, Yu T, et al
    1363: EFFECT OF ULINASTATIN ON MICROCIRCULATION DURING SEPSIS IN A RAT CECAL LIGATION AND PUNCTURE MODEL.
    Crit Care Med. 2016;44.
    PubMed    


  425. VALLABHAJOSYULA S, Jentzer J, Geske J, Kashani K, et al
    1362: LONG-TERM NEW-ONSET HEART FAILURE IN PATIENTS WITH MYOCARDIAL DYSFUNCTION IN SEPSIS AND SEPTIC SHOCK.
    Crit Care Med. 2016;44.
    PubMed    


  426. WALSH M, Hobbs B, Giancarelli A, Bhullar I, et al
    1357: THE EFFECT OF OBESITY ON MORTALITY IN TRAUMA PATIENTS WITH SEPSIS.
    Crit Care Med. 2016;44.
    PubMed    


  427. TAYLOR B, Alexander M, Karvestski C, Templin M, et al
    1354: AN AGGRESSIVE SEPSIS IDENTIFICATION INITIATIVE INCREASES FALSE-POSITIVE DIAGNOSES.
    Crit Care Med. 2016;44.
    PubMed    


  428. LANTRY J, April M
    1353: SEPSIS CLINICAL CRITERIA IN ED PATIENTS ADMITTED TO AN ICU: AN EXTERNAL VALIDATION STUDY OF QSOFA.
    Crit Care Med. 2016;44.
    PubMed    


  429. HAILESELASSIE B, Su E, Nino D, Liu H, et al
    1352: IMPACT OF MITOCHONDRIAL ROS SCAVENGERS ON CARDIAC MECHANICS IN A MURINE MODEL OF SEPSIS.
    Crit Care Med. 2016;44.
    PubMed    


  430. KAWANO Y, Hoshino K, Irie Y, Izutani Y, et al
    1347: USEFULNESS OF SEPSIS BIOMARKERS ACCORDING TO THE NEW DEFINITIONS OF SEPSIS.
    Crit Care Med. 2016;44.
    PubMed    


  431. REILLY J, Shashaty M, Anderson B, Palakshappa J, et al
    1344: PLASMA RIP3, A REGULATOR OF NECROPTOSIS, IS ASSOCIATED WITH MORTALITY & ORGAN DYSFUNCTION IN SEPSIS.
    Crit Care Med. 2016;44.
    PubMed    


  432. WEST A, Mangubat PM, Giles K, Guynn A, et al
    1343: ANALYZING ACCURACY AND EARLY DETERMINANTS OF SEVERE SEPSIS USING REAL-TIME EMR INTEGRATED ALGORITHM.
    Crit Care Med. 2016;44.
    PubMed    


  433. TYLER P, Celi LA, Rush B
    1342: INTERHOSPITAL TRANSFER OF PATIENTS WITH SEPSIS ACROSS THE UNITED STATES.
    Crit Care Med. 2016;44.
    PubMed    


  434. MARIK P, Bittner E, Hansell D, Sahatjian J, et al
    1341: FLUID ADMINISTRATION IN SEPSIS/SEPTIC SHOCK, PATTERNS AND OUTCOMES: LARGE NATIONAL DATABASE ANALYSIS.
    Crit Care Med. 2016;44.
    PubMed    


  435. AMES S, Davis B, Carcillo J, Angus D, et al
    1338: HOSPITAL-LEVEL VARIATION IN RISK-ADJUSTED MORTALITY FOR PEDIATRIC SEPSIS.
    Crit Care Med. 2016;44.
    PubMed    


  436. MAYR F, Balakumar V, Talisa V, Fine M, et al
    1336: UNDERSTANDING THE BURDEN OF UNPLANNED SEPSIS READMISSIONS.
    Crit Care Med. 2016;44.
    PubMed    


  437. SALOMON J, Serrao K, Guardiola J, Bonura A, et al
    1335: EARLY DETECTION OF PEDIATRIC SEPSIS USING AN ELECTRONIC MEDICAL RECORD-BASED SCREENING TOOL.
    Crit Care Med. 2016;44.
    PubMed    


  438. LU M, Chen E
    1334: MMF PROTECTS AGAINST LIVER INJURY DURING SEPSIS VIA REGULATION OF MAPK AND NF-KappaB PATHWAYS.
    Crit Care Med. 2016;44.
    PubMed    


  439. PROUT A, Talisa V, Mayr F, Yende S, et al
    1333: PEDIATRIC SEPSIS AND SEPTIC SHOCK: RISK FACTORS AND COMORBID CONDITIONS.
    Crit Care Med. 2016;44.
    PubMed    


  440. KASAL J, Stoll B, Katyal A, Tannehill D, et al
    1331: ASSESSMENT OF QSOFA AND OTHER CRITERIA IN SEPSIS WITH NORMAL BLOOD PRESSURE AND INTERMEDIATE LACTATE.
    Crit Care Med. 2016;44.
    PubMed    


  441. ZHANG LA, Parker R, Banerjee I, Clermont G, et al
    1330: SEPSIS ENDOTYPES AND THEIR PHYSIOLOGIC CHARACTERIZATION USING VITAL SIGNS.
    Crit Care Med. 2016;44.
    PubMed    


  442. FAY K, Klingensmith N, Lyons J, Ramonell K, et al
    1329: CD43 SIGNALING CONTROLS SURVIVAL, TH2 SKEWING, AND MEMORY T CELL APOPTOSIS DURING SEPSIS.
    Crit Care Med. 2016;44.
    PubMed    


  443. KILLIEN E, Farris R, Watson R, Flanagin M, et al
    1328: DETERIORATION IN HEALTH-RELATED QUALITY OF LIFE IS COMMON AMONG CHILDREN SURVIVING SEPSIS.
    Crit Care Med. 2016;44.
    PubMed    


  444. MENG X, Zhai Y, Ao L, Hui H, et al
    1326: AGING ELEVATES MYOCARDIAL TLR2 LEVELS TO AUGMENT CARDIAC DYSFUNCTION AND MORTALITY DURING SEPSIS.
    Crit Care Med. 2016;44.
    PubMed    


  445. SUZUKI K, Okada H, Takada C, Oda K, et al
    1325: HYDROCORTISONE THERAPY WITH CAR PEPTIDE PROTECTS THE INJURED ENDOTHELIAL GLYCOCALYX IN SEPSIS.
    Crit Care Med. 2016;44.
    PubMed    


  446. FOUNTAIN S, Perry J 3rd, Stoffer B, Raschke R, et al
    1278: DESIGN OF AN ELECTRONIC MEDICAL RECORD-BASED ALERT SYSTEM TO DETECT THE ONSET OF SEVERE SEPSIS.
    Crit Care Med. 2016;44.
    PubMed    


  447. PENOYER D, Snyder J, Inderwiesen P, Geddie P, et al
    1229: SEPSIS CORE MEASURES AND BLOOD CULTURE DOCUMENTATION: TIMING IS EVERYTHING!
    Crit Care Med. 2016;44.
    PubMed    


  448. BORGES N, Bavare A, Cruz A, Patel B, et al
    1204: RAPID RESPONSE TO PEDIATRIC SEPSIS IN A TERTIARY CHILDREN'S HOSPITAL: BATTLING COMPLEXITY.
    Crit Care Med. 2016;44.
    PubMed    


  449. BALDAWI M, Al-Jubouri M, Watson J, Kathrin Jaehne A, et al
    1104: THE POTENTIAL FINANCIAL CONSEQUENCE OF THE NEW SEPSIS-3 SEPSIS DEFINITIONS.
    Crit Care Med. 2016;44.
    PubMed    


  450. BLAHA K, Diaz F, Quilodran J, Medina T, et al
    934: SAFETY AND EFFICACY OF A PREVENTIVE STRATEGY FOR FLUID OVERLOAD IN CHILDREN WITH SEPSIS AND PARDS.
    Crit Care Med. 2016;44.
    PubMed    


  451. PANG D, Wu Y, Cummings J, Panigrahy A, et al
    721: MICROGLIAL ACTIVATION CORRELATES WITH CYTOTOXIC EDEMA IN A MURINE MODEL OF SEPSIS.
    Crit Care Med. 2016;44.
    PubMed    


  452. SADAKA F, Korobey M, Dumm A, Wegener G, et al
    692: PRACTICE PATTERNS FOR ANTIBIOTIC DE-ESCALATION IN MRSA CULTURE-NEGATIVE SEPSIS.
    Crit Care Med. 2016;44.
    PubMed    


  453. ZILBERBERG M, Nathanson B, Sulham K, Fan W, et al
    645: HOSPITAL RESOURCE USE ASSOCIATED WITH TREATMENT OF ACINETOBACTER BAUMANNII PNEUMONIA AND SEPSIS.
    Crit Care Med. 2016;44.
    PubMed    


  454. ALCAMO A, Alessi L, Noona Vehovic S, Pang D, et al
    626: MULTIDRUG-RESISTANT ORGANISM SEPSIS IN PEDIATRIC LIVER TRANSPLANT RECIPIENTS: A BURGEONING PROBLEM.
    Crit Care Med. 2016;44.
    PubMed    


  455. GUL F, Kemal Arslantas M, Bilgili B, Besir A, et al
    482: SERUM VITAMIN D LEVEL VARIATION IN SIRS, SEPSIS, AND SEPTIC SHOCK.
    Crit Care Med. 2016;44.
    PubMed    


  456. HASSINGER A, Breuer R
    434: SEPSIS DRILLS: A MULTIDISCIPLINARY SEPSIS EDUCATIONAL PROGRAM IN A PEDIATRIC HOSPITAL.
    Crit Care Med. 2016;44.
    PubMed    


  457. VILLAR J, Lighthall G
    333: SERUM LACTATE LEVEL PREDICTS 3-DAY, 30-DAY, AND 1-YEAR MORTALITY IN PATIENTS WITH AND WITHOUT SEPSIS.
    Crit Care Med. 2016;44.
    PubMed    


  458. MORGAN R, Sutton R, Kilbaugh T, Lautz A, et al
    287: PULMONARY VASODILATOR THERAPY IN A SWINE MODEL OF PEDIATRIC SEPSIS-ASSOCIATED CARDIAC ARREST.
    Crit Care Med. 2016;44.
    PubMed    


  459. VALLABHAJOSYULA S, Kashyap R, Geske J, Sakhuja A, et al
    185: DOPPLER-DEFINED ACUTE PULMONARY HYPERTENSION IN SEPSIS AND SEPTIC SHOCK.
    Crit Care Med. 2016;44.
    PubMed    


  460. HIRATA JI, Ohya M
    107: OXIDANT/ANTIOXIDANT TREATMENT INFLUENCES PULMONARY DNA VIA MTH1 MODIFICATIONS IN SEPSIS-INDUCED ALI.
    Crit Care Med. 2016;44.
    PubMed    


  461. VALLABHAJOSYULA S, Kashyap R, Geske J, Kumar M, et al
    28: RIGHT VENTRICULAR DYSFUNCTION IN SEPSIS AND SEPTIC SHOCK: AN EIGHT-YEAR ANALYSIS.
    Crit Care Med. 2016;44.
    PubMed    


  462. VALLABHAJOSYULA S, Jentzer J, Geske J, Sakhuja A, et al
    23: CARDIORENAL SYNDROME IN SEPSIS AND SEPTIC SHOCK: THE MAYO CLINIC EXPERIENCE.
    Crit Care Med. 2016;44.
    PubMed    


  463. KATSIOS C, Doumouras A, Shaefi S, Novack V, et al
    22: CONSERVATIVE FLUID STRATEGIES DECREASE MORTALITY IN SEPSIS: A SYSTEMATIC REVIEW AND META-ANALYSIS.
    Crit Care Med. 2016;44.
    PubMed    


  464. HIRANO Y, Aziz M, Weng-Lang Y, Ochani M, et al
    21: THE ROLE OF JUNCTIONAL ADHESION MOLECULE C IN THE AGING PHENOTYPE OF NEUTROPHILS DURING SEPSIS.
    Crit Care Med. 2016;44.
    PubMed    


  465. JOHNSON A, Celi LA, Raffa J, Pollard T, et al
    18: EXTERNAL VALIDATION OF THE SEPSIS-3 GUIDELINES.
    Crit Care Med. 2016;44.
    PubMed    


  466. ENKHBAATAR P
    Cellular Therapy for Sepsis: A New Hope?
    Crit Care Med. 2016;44:2296-2298.
    PubMed    


  467. KEMPKER JA, Martin GS
    Does Sepsis Case Mix Heterogeneity Prevent Outcome Comparisons?
    Crit Care Med. 2016;44:2288-2289.
    PubMed    


  468. TOWNSEND SR
    Collaborating for Success in Sepsis Quality Improvement.
    Crit Care Med. 2016;44:2275-2277.
    PubMed    


    November 2016
  469. ZHANG Z, Li Q
    Identifying Sepsis in Clinical Database With Sepsis-3 Definition.
    Crit Care Med. 2016;44:e1145-e1146.
    PubMed    


  470. ZIMMERMAN JJ, Davis R
    Imprecise (Sepsis) Medicine Can Become Precise.
    Crit Care Med. 2016;44:e1143-e1144.
    PubMed    


  471. SAVEL RH, Simon RJ, Kupfer Y
    Unraveling the Mysterious Relationship Between Obesity and Outcomes in Patients With Sepsis.
    Crit Care Med. 2016;44:2104-2105.
    PubMed    


  472. COHEN M, Falcone P, Kusnezov D, Paragas J, et al
    Sepsis and Presidential Initiatives.
    Crit Care Med. 2016;44:1963-1965.
    PubMed    


    October 2016
  473. JAEHNE AK, Rivers EP
    Early Liberal Fluid Therapy for Sepsis Patients Is Not Harmful: Hydrophobia Is Unwarranted but Drink Responsibly.
    Crit Care Med. 2016.
    PubMed    


  474. YOUKEE D, Hulme W, Roberts T, Daniels R, et al
    Time Matters: Antibiotic Timing in Sepsis and Septic Shock.
    Crit Care Med. 2016;44:e1016-e1017.
    PubMed    


  475. SHIRAKURA Y, Kuriyama A
    Timing of Antibiotic Administration in Sepsis and Septic Shock: The Impact That a Meta-Analysis Does Not Depict.
    Crit Care Med. 2016;44:e1004.
    PubMed    


  476. MARRARO GA, Genovese U
    The Treatment of Severe Sepsis in the Pediatric Age: Long-Awaited Prospects and New Challenges Are Looming.
    Crit Care Med. 2016;44:1960-1962.
    PubMed    


    September 2016
  477. PREAU S, Bortolotti P, Colling D, Dewavrin F, et al
    Diagnostic Accuracy of the Inferior Vena Cava Collapsibility to Predict Fluid Responsiveness in Spontaneously Breathing Patients With Sepsis and Acute Circulatory Failure.
    Crit Care Med. 2016.
    PubMed     Abstract available


  478. SWEENEY TE, Khatri P
    Benchmarking Sepsis Gene Expression Diagnostics Using Public Data.
    Crit Care Med. 2016.
    PubMed     Abstract available


  479. SCHEER CS, Fuchs C, Kuhn SO, Vollmer M, et al
    Quality Improvement Initiative for Severe Sepsis and Septic Shock Reduces 90-Day Mortality: A 7.5-Year Observational Study.
    Crit Care Med. 2016.
    PubMed     Abstract available


  480. ZIMMERMAN JJ, Sullivan E, Yager TD, Cheng C, et al
    Diagnostic Accuracy of a Host Gene Expression Signature That Discriminates Clinical Severe Sepsis Syndrome and Infection-Negative Systemic Inflammation Among Critically Ill Children.
    Crit Care Med. 2016.
    PubMed     Abstract available


  481. SEPULVEDA M, Gonano LA, Viotti M, Morell M, et al
    Calcium/Calmodulin Protein Kinase II-Dependent Ryanodine Receptor Phosphorylation Mediates Cardiac Contractile Dysfunction Associated With Sepsis.
    Crit Care Med. 2016.
    PubMed     Abstract available


  482. MIRA JC, Gentile LF, Mathias BJ, Efron PA, et al
    Sepsis Pathophysiology, Chronic Critical Illness, and Persistent Inflammation-Immunosuppression and Catabolism Syndrome.
    Crit Care Med. 2016.
    PubMed     Abstract available


  483. DALLI J, Colas RA, Quintana C, Barragan-Bradford D, et al
    Human Sepsis Eicosanoid and Proresolving Lipid Mediator Temporal Profiles: Correlations With Survival and Clinical Outcomes.
    Crit Care Med. 2016.
    PubMed     Abstract available


  484. MELLA JR, Chiswick E, Stepien D, Moitra R, et al
    Antagonism of the Neurokinin-1 Receptor Improves Survival in a Mouse Model of Sepsis by Decreasing Inflammation and Increasing Early Cardiovascular Function.
    Crit Care Med. 2016.
    PubMed     Abstract available


  485. PAREKH D, Patel JM, Scott A, Lax S, et al
    Vitamin D Deficiency in Human and Murine Sepsis.
    Crit Care Med. 2016.
    PubMed     Abstract available


  486. AARVOLD AB, Ryan HM, Magee LA, von Dadelszen P, et al
    Multiple Organ Dysfunction Score Is Superior to the Obstetric-Specific Sepsis in Obstetrics Score in Predicting Mortality in Septic Obstetric Patients.
    Crit Care Med. 2016.
    PubMed     Abstract available


  487. OAMI T, Watanabe E, Hatano M, Sunahara S, et al
    Suppression of T Cell Autophagy Results in Decreased Viability and Function of T Cells Through Accelerated Apoptosis in a Murine Sepsis Model.
    Crit Care Med. 2016.
    PubMed     Abstract available


  488. BEESLEY SJ, Wilson EL, Lanspa MJ, Grissom CK, et al
    Relative Bradycardia in Patients With Septic Shock Requiring Vasopressor Therapy.
    Crit Care Med. 2016.
    PubMed     Abstract available


  489. MOHR NM, Harland KK, Shane DM, Ahmed A, et al
    Rural Patients With Severe Sepsis or Septic Shock who Bypass Rural Hospitals Have Increased Mortality: An Instrumental Variables Approach.
    Crit Care Med. 2016.
    PubMed     Abstract available


  490. MARTINEZ ML, Ferrer R, Torrents E, Guillamat-Prats R, et al
    Impact of Source Control in Patients With Severe Sepsis and Septic Shock.
    Crit Care Med. 2016.
    PubMed     Abstract available


    April 2016
  491. RHEE C
    Cytokine Imbalance Predicts Poor Outcomes in Staphylococcus aureus Bacteremia--But What Can We Do About It?
    Crit Care Med. 2016;44:846-7.
    PubMed    


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