Retrieve available abstracts of 80 articles: HTML format
Single Articles
August 2025
HALVORSEN P, Marks-Hultstrom M, Wallin E, Ahlstrom B, et al Post-sepsis recovery: perspectives on measuring what matters. Author's reply.
Intensive Care Med. 2025 Aug 28. doi: 10.1007/s00134-025-08096. PubMed
HALVORSEN P, Marks-Hultstrom M, Wallin E, Ahlstrom B, et al Challenges in assessing HRQoL after ICU sepsis: Author's reply.
Intensive Care Med. 2025 Aug 19. doi: 10.1007/s00134-025-08083. PubMed
July 2025
CUMMINGS MJ, Lutwama JJ, Tomoiaga AS, Zhao M, et al Identification of transcriptomic sepsis endotypes in sub-Saharan Africa:
derivation, validation, and global alignment in two Ugandan cohorts.
Intensive Care Med. 2025 Jul 29. doi: 10.1007/s00134-025-08047. PubMedAbstract available
WANG J, Wang Y, Guo J Challenges in assessing HRQoL after ICU sepsis.
Intensive Care Med. 2025 Jul 28. doi: 10.1007/s00134-025-08051. PubMed
SZARPAK L, Rybczynski B, Krupa A, Pruc M, et al Post-sepsis recovery: perspectives on measuring what matters.
Intensive Care Med. 2025 Jul 24. doi: 10.1007/s00134-025-08055. PubMed
ANNANE D, Briegel J, Seymour CW Corticosteroids in sepsis: certainties and shadows.
Intensive Care Med. 2025 Jul 23. doi: 10.1007/s00134-025-08044. PubMed
VAIDIE J, Demiselle J, Gabriel A, Guillon A, et al Effect of temporary suspension of chronic immunosuppressive drugs on day-90
mortality and ICU-acquired infections among critically Ill patients with solid
organ transplant: a retrospective multicenter study.
Intensive Care Med. 2025 Jul 16. doi: 10.1007/s00134-025-08024. PubMedAbstract available
TABAH A, De Waele J, Ssi Yan Kai N, Aslan AT, et al Source control in bloodstream infections in patients with sepsis, septic shock,
or requiring ICU admission: a scoping review with recommendations for
standardizing research.
Intensive Care Med. 2025 Jul 14. doi: 10.1007/s00134-025-08026. PubMedAbstract available
DEMISELLE J, Ferrer R, Besen B Hemodynamic targets in the initial resuscitation of older patients with sepsis:
time for a reappraisal?
Intensive Care Med. 2025 Jul 3. doi: 10.1007/s00134-025-08010. PubMed
June 2025
HALVORSEN P, Marks-Hultstrom M, Wallin E, Ahlstrom B, et al Health-related quality of life and functional recovery after intensive care for
sepsis in a national cohort.
Intensive Care Med. 2025 Jun 23. doi: 10.1007/s00134-025-07998. PubMedAbstract available
PAYEN D, Velho TR, Moita LF Beyond inflammation: the role of metabolic dysregulation in sepsis diagnosis and
treatment.
Intensive Care Med. 2025 Jun 3. doi: 10.1007/s00134-025-07948. PubMed
May 2025
KLOMPAS M, Lapao LV, Taylor SP Antibiotics for suspected sepsis: who and when?
Intensive Care Med. 2025 May 19. doi: 10.1007/s00134-025-07940. PubMed
ENDO A, Yamakawa K, Tagami T, Umemura Y, et al Efficacy of targeting high mean arterial pressure for older patients with septic
shock (OPTPRESS): a multicentre, pragmatic, open-label, randomised controlled
trial.
Intensive Care Med. 2025;51:883-892. PubMedAbstract available
April 2025
HILL TM, Kerivan LT, Vilain KA, Windham S, et al Decision analysis model of rapid versus deferred antibiotic initiation in
patients with suspected sepsis in the emergency department.
Intensive Care Med. 2025 Apr 29. doi: 10.1007/s00134-025-07899. PubMedAbstract available
DOUGLAS AO, Shelton KT Correspondence on "Management of adult sepsis in resource-limited settings:
global expert consensus statements using a Delphi method".
Intensive Care Med. 2025 Apr 3. doi: 10.1007/s00134-025-07858. PubMed
March 2025
ANTCLIFFE DB, Burrell A, Boyle AJ, Gordon AC, et al Sepsis subphenotypes, theragnostics and personalized sepsis care.
Intensive Care Med. 2025 Mar 31. doi: 10.1007/s00134-025-07873. PubMedAbstract available
MEKONTSO DESSAP A, AlShamsi F, Belletti A, De Backer D, et al European Society of Intensive Care Medicine (ESICM) 2025 clinical practice
guideline on fluid therapy in adult critically ill patients: part 2-the volume of
resuscitation fluids.
Intensive Care Med. 2025 Mar 31. doi: 10.1007/s00134-025-07840. PubMedAbstract available
KALIL AC, Povoa P, Leone M Subphenotypes and phenotypes to resolve sepsis heterogeneity: hype or hope?
Intensive Care Med. 2025 Mar 6. doi: 10.1007/s00134-025-07828. PubMed
GAJDOS L, Buetti N, Tabah A, Ruckly S, et al Shortening antibiotic therapy duration for hospital-acquired bloodstream
infections in critically ill patients: a causal inference model from the
international EUROBACT-2 database.
Intensive Care Med. 2025;51:518-528. PubMedAbstract available
ANTCLIFFE DB, Harte E, Hussain H, Jimenez B, et al Metabolic septic shock sub-phenotypes, stability over time and association with
clinical outcome.
Intensive Care Med. 2025;51:529-541. PubMedAbstract available
February 2025
SPRIET I, Gijsen M, Peetermans M, Debaveye Y, et al Continuous infusion of beta-lactam antibiotics in critically ill patients with
sepsis: insights from daily clinical practice.
Intensive Care Med. 2025 Feb 17. doi: 10.1007/s00134-025-07819. PubMed
January 2025
RYNNE J, Mosavie M, Masse MH, Menard J, et al Sepsis subtypes and differential treatment response to vitamin C: biological
sub-study of the LOVIT trial.
Intensive Care Med. 2025 Jan 7. doi: 10.1007/s00134-024-07733. PubMedAbstract available
VIGNON P, Charron C, Legras A, Musset F, et al Left ventricular diastolic dysfunction is prevalent but not associated with
mortality in patients with septic shock.
Intensive Care Med. 2025;51:94-105. PubMedAbstract available
December 2024
THWAITES L, Nasa P, Abbenbroek B, Dat VQ, et al Management of adult sepsis in resource-limited settings: global expert consensus
statements using a Delphi method.
Intensive Care Med. 2024 Dec 23. doi: 10.1007/s00134-024-07735. PubMedAbstract available
BLOOS F, Bogatsch H, Netea MG, Giamarellos-Bourboulis EJ, et al Effects of delayed consent on patient characteristics in adult patients with
sepsis.
Intensive Care Med. 2024 Dec 12. doi: 10.1007/s00134-024-07718. PubMed
SCHAUMBURG T, Kohler N, Breitenstein Y, Kolbe-Busch S, et al EFFECT of daily antiseptic bathing with octenidine on ICU-acquired bacteremia and
ICU-acquired multidrug-resistant organisms: a multicenter, cluster-randomized,
double-blind, placebo-controlled, cross-over study.
Intensive Care Med. 2024;50:2073-2082. PubMedAbstract available
WALSHAM J, Hammond N, Blumenthal A, Cohen J, et al Fludrocortisone dose-response relationship in septic shock: a randomised phase II
trial.
Intensive Care Med. 2024;50:2050-2060. PubMedAbstract available
November 2024
MARTIN-LOECHES I, Singer M, Leone M Sepsis: key insights, future directions, and immediate goals. A review and expert
opinion.
Intensive Care Med. 2024 Nov 12. doi: 10.1007/s00134-024-07694. PubMedAbstract available
RANZANI O, Annane D, Singer M Fludrocortisone with hydrocortisone in sepsis: new evidence in an ongoing debate.
Intensive Care Med. 2024 Nov 12. doi: 10.1007/s00134-024-07699. PubMed
October 2024
BAILLIE JK, Angus D, Burnham K, Calandra T, et al Causal inference can lead us to modifiable mechanisms and informative archetypes
in sepsis.
Intensive Care Med. 2024 Oct 21. doi: 10.1007/s00134-024-07665. PubMedAbstract available
BHAVANI SV, Spicer A, Sinha P, Malik A, et al Distinct immune profiles and clinical outcomes in sepsis subphenotypes based on
temperature trajectories.
Intensive Care Med. 2024 Oct 9. doi: 10.1007/s00134-024-07669. PubMedAbstract available
REHBERG S, Frank S, Cerny V, Cihlar R, et al Landiolol for heart rate control in patients with septic shock and persistent
tachycardia. A multicenter randomized clinical trial (Landi-SEP).
Intensive Care Med. 2024;50:1622-1634. PubMedAbstract available
September 2024
BARTON G, Rickard CM, Roberts JA Continuous infusion of beta-lactam antibiotics in critically ill patients with
sepsis: implementation considerations.
Intensive Care Med. 2024 Sep 23. doi: 10.1007/s00134-024-07650. PubMed
FREUND Y, Cancella de Abreu M, Bloom B Effect of the 1-h bundle on mortality in patients with suspected sepsis in the
emergency department: faster is better for the sicker ones! Author's reply.
Intensive Care Med. 2024 Sep 4. doi: 10.1007/s00134-024-07605. PubMed
JOUFFROY R, Vivien B, Gueye P Effect of the 1-h bundle on mortality in patients with suspected sepsis in the
emergency department: faster is better for the sicker ones!
Intensive Care Med. 2024 Sep 4. doi: 10.1007/s00134-024-07594. PubMed
GIRARDIS M, David S, Ferrer R, Helms J, et al Understanding, assessing and treating immune, endothelial and haemostasis
dysfunctions in bacterial sepsis.
Intensive Care Med. 2024 Sep 2. doi: 10.1007/s00134-024-07586. PubMedAbstract available
AHLSTEDT C, Sivapalan P, Rooyackers O, Perner A, et al Complex interaction of infusion volumes and confounding factors with lactate
clearance in septic shock. Author's reply.
Intensive Care Med. 2024;50:1547-1548. PubMed
TEJA B, Pereira TV, Law AC, Mazer CD, et al Effectiveness of fludrocortisone and hydrocortisone versus hydrocortisone alone
in septic shock with and without pneumonia.
Intensive Care Med. 2024;50:1535-1537. PubMed
ISHII J, Ohshimo S, Nishikimi M, Kyo M, et al Complex interaction of infusion volumes and confounding factors with lactate
clearance in septic shock.
Intensive Care Med. 2024;50:1545-1546. PubMed
August 2024
FREUND Y, Cancella de Abreu M, Lebal S, Rousseau A, et al Correction: Effect of the 1-h bundle on mortality in patients with suspected
sepsis in the emergency department: a stepped wedge cluster randomized clinical
trial.
Intensive Care Med. 2024 Aug 12. doi: 10.1007/s00134-024-07600. PubMed
June 2024
HELMS J, Povoa P, Jaber S Refining trial design in sepsis management: balancing realism with ideal
outcomes.
Intensive Care Med. 2024 Jun 26. doi: 10.1007/s00134-024-07521. PubMed
FREUND Y, de Abreu MC, Lebal S, Rousseau A, et al Effect of the 1-h bundle on mortality in patients with suspected sepsis in the
emergency department: a stepped wedge cluster randomized clinical trial.
Intensive Care Med. 2024 Jun 24. doi: 10.1007/s00134-024-07509. PubMedAbstract available
MEZIANI F, Iba T, Levy JH, Helms J, et al Sepsis-induced coagulopathy: a matter of timeline.
Intensive Care Med. 2024 Jun 10. doi: 10.1007/s00134-024-07507. PubMed
MONGARDON N, Vincent JL Outcome of hospital-acquired bloodstream infection: interplay between bacteria,
host, and healthcare system organization.
Intensive Care Med. 2024;50:925-927. PubMed
BUETTI N, Tabah A, Setti N, Ruckly S, et al The role of centre and country factors on process and outcome indicators in
critically ill patients with hospital-acquired bloodstream infections.
Intensive Care Med. 2024;50:873-889. PubMedAbstract available
May 2024
NEDEL WL, Portela LV Lactate levels in sepsis: don't forget the mitochondria.
Intensive Care Med. 2024 May 23. doi: 10.1007/s00134-024-07475. PubMed
ARABI YM, Belley-Cote E, Carsetti A, De Backer D, et al European Society of Intensive Care Medicine clinical practice guideline on fluid
therapy in adult critically ill patients. Part 1: the choice of resuscitation
fluids.
Intensive Care Med. 2024 May 21. doi: 10.1007/s00134-024-07369. PubMedAbstract available
LEONE M, Nielsen ND, Russell L Ten tips on sepsis-induced thrombocytopenia.
Intensive Care Med. 2024 May 13. doi: 10.1007/s00134-024-07478. PubMed
ZIMMERMANN T, Brealey D, Singer M Diagnosing sepsis: where we're at and where we're going.
Intensive Care Med. 2024 May 2. doi: 10.1007/s00134-024-07428. PubMed
AHLSTEDT C, Sivapalan P, Kriz M, Jacobson G, et al Effects of restrictive fluid therapy on the time to resolution of hyperlactatemia
in ICU patients with septic shock. A secondary post hoc analysis of the CLASSIC
randomized trial.
Intensive Care Med. 2024;50:678-686. PubMedAbstract available
April 2024
CHAI MG, Tu Q, Cotta MO, Bauer MJ, et al Correction: Achievement of therapeutic antibiotic exposures using Bayesian dosing
software in critically unwell children and adults with sepsis.
Intensive Care Med. 2024 Apr 2. doi: 10.1007/s00134-024-07393. PubMed
ZHAO Y, Zang B, Wang Q The effectiveness of alkaline phosphatase in sepsis-associated acute kidney
injury.
Intensive Care Med. 2024 Apr 2. doi: 10.1007/s00134-024-07392. PubMed
HERNANDEZ G, Carmona P, Ait-Oufella H Monitoring capillary refill time in septic shock.
Intensive Care Med. 2024;50:580-582. PubMed
KATTAN E, Ibarra-Estrada M, Jung C Knowing the ropes of vasopressor dosing: a focus on norepinephrine.
Intensive Care Med. 2024;50:587-589. PubMed
March 2024
CHAI GG, Tu Q, Cotta MO, Bauer MJ, et al Achievement of therapeutic antibiotic exposures using Bayesian dosing software in
critically unwell children and adults with sepsis.
Intensive Care Med. 2024 Mar 13. doi: 10.1007/s00134-024-07353. PubMedAbstract available
PICKKERS P, Angus DC, Bass K, Bellomo R, et al Correction: Phase-3 trial of recombinant human alkaline phosphatase for patients
with sepsis-associated acute kidney injury (REVIVAL).
Intensive Care Med. 2024 Mar 4. doi: 10.1007/s00134-024-07357. PubMed
AHLSTROM B, Larsson IM, Strandberg G, Lipcsey M, et al Association of sepsis with long-term mortality and causes of death in the Swedish
intensive care cohort.
Intensive Care Med. 2024 Mar 4. doi: 10.1007/s00134-024-07370. PubMed
DE BACKER D, Hajjar L, Monnet X Vasoconstriction in septic shock.
Intensive Care Med. 2024;50:459-462. PubMed
KREITMANN L, Helms J, Martin-Loeches I, Salluh J, et al ICU-acquired infections in immunocompromised patients.
Intensive Care Med. 2024;50:332-349. PubMedAbstract available
January 2024
PROWLE JR, Bagshaw SM, Forni LG Tackling sepsis-associated AKI: are there any chances of REVIVAL with new
approaches?
Intensive Care Med. 2024 Jan 10. doi: 10.1007/s00134-023-07294. PubMed
PICKKERS P, Angus DC, Bass K, Bellomo R, et al Phase-3 trial of recombinant human alkaline phosphatase for patients with
sepsis-associated acute kidney injury (REVIVAL).
Intensive Care Med. 2024 Jan 3. doi: 10.1007/s00134-023-07271. PubMedAbstract available
ZAMPIERI FG, Machado FR, Veiga VC, Azevedo LCP, et al Determinants of fluid use and the association between volume of fluid used and
effect of balanced solutions on mortality in critically ill patients: a secondary
analysis of the BaSICS trial.
Intensive Care Med. 2024;50:79-89. PubMedAbstract available
November 2023
BALIK M, Maly M, Brozek T, Rulisek J, et al Propafenone versus amiodarone for supraventricular arrhythmias in septic shock: a
randomised controlled trial.
Intensive Care Med. 2023;49:1283-1292. PubMedAbstract available
October 2023
FOWLER C, Scordo M, Chawla S The EAS(E)IX of predicting sepsis after allogeneic hematopoietic cell
transplantation.
Intensive Care Med. 2023 Oct 24. doi: 10.1007/s00134-023-07242. PubMed
VAN AMSTEL RBE, Kennedy JN, Scicluna BP, Bos LDJ, et al Uncovering heterogeneity in sepsis: a comparative analysis of subphenotypes.
Intensive Care Med. 2023 Oct 18. doi: 10.1007/s00134-023-07239. PubMedAbstract available
ZHANG Z, Chen L, Liu X, Yang J, et al Exploring disease axes as an alternative to distinct clusters for characterizing
sepsis heterogeneity.
Intensive Care Med. 2023 Oct 4. doi: 10.1007/s00134-023-07226. PubMedAbstract available
September 2023
WHITE KC, Laupland KB, Tabah A, Ramanan M, et al Details and the devil within: the case of sepsis associated AKI. Author's reply.
Intensive Care Med. 2023 Sep 10. doi: 10.1007/s00134-023-07209. PubMed
August 2023
GOMEZ H, Zarbock A Details and the devil within - the case of sepsis associated acute kidney injury.
Intensive Care Med. 2023 Aug 31. doi: 10.1007/s00134-023-07204. PubMed
WHITE KC, Laupland KB, Tabah A, Ramanan M, et al Clinical implications of urine output-based sepsis-associated acute kidney
injury. Author's reply.
Intensive Care Med. 2023 Aug 28. doi: 10.1007/s00134-023-07205. PubMed
CLAURE-DEL GRANADO R, James MT, Legrand M Tackling sepsis-associated acute kidney injury using routinely collected data.
Intensive Care Med. 2023 Aug 28. doi: 10.1007/s00134-023-07200. PubMed
GIAMARELLOS-BOURBOULIS EJ, Zinkernagel AS, De Robertis E, Azoulay E, et al Correction: Sepsis, a call for inclusion in the work plan of the European Center
for Disease Prevention and Control.
Intensive Care Med. 2023 Aug 24. doi: 10.1007/s00134-023-07197. PubMed
KORELL F, DeFilipp Z, Schreck N, Luft T, et al Validation of pre-conditioning EASIX for prediction of sepsis after allogeneic
stem cell transplantation.
Intensive Care Med. 2023 Aug 23. doi: 10.1007/s00134-023-07193. PubMed
KASUGAI D, Nakashima T, Goto T Clinical implications of urine output-based sepsis-associated acute kidney
injury.
Intensive Care Med. 2023 Aug 21. doi: 10.1007/s00134-023-07190. PubMed
GIAMARELLOS-BOURBOULIS EJ, Zinkernagel AS, De Robertis E, Azoulay E, et al Sepsis, a call for inclusion in the work plan of the European Center for Disease
Prevention and Control.
Intensive Care Med. 2023 Aug 1. doi: 10.1007/s00134-023-07127. PubMed
July 2023
REILLY JP, Zhao Z, Shashaty MGS, Koyama T, et al Exposure to ambient air pollutants and acute respiratory distress syndrome risk
in sepsis.
Intensive Care Med. 2023 Jul 20. doi: 10.1007/s00134-023-07148. PubMedAbstract available
WHITE KC, Serpa-Neto A, Hurford R, Clement P, et al Sepsis-associated acute kidney injury in the intensive care unit: incidence,
patient characteristics, timing, trajectory, treatment, and associated outcomes.
A multicenter, observational study.
Intensive Care Med. 2023 Jul 11. doi: 10.1007/s00134-023-07138. PubMedAbstract available
KJAER MN, Meyhoff TS, Sivapalan P, Granholm A, et al Long-term effects of restriction of intravenous fluid in adult ICU patients with
septic shock.
Intensive Care Med. 2023;49:820-830. PubMedAbstract available
June 2023
ZHANG C, Zhang X, Sun Z, Liu X, et al MetaSepsisBase: a biomarker database for systems biological analysis and
personalized diagnosis of heterogeneous human sepsis.
Intensive Care Med. 2023 Jun 17. doi: 10.1007/s00134-023-07126. PubMed
BRUNO RR, Wollborn J, Fengler K, Flick M, et al Direct assessment of microcirculation in shock: a randomized-controlled
multicenter study.
Intensive Care Med. 2023;49:645-655. PubMedAbstract available
April 2023
BOLDT J, Muller M, Kuhn D, Linke LC, et al Retraction Note: Circulating adhesion molecules in the critically ill: A
comparison between trauma and sepsis patients.
Intensive Care Med. 2023 Apr 4. doi: 10.1007/s00134-023-07055. PubMed