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Sepsis

Free Subscription Articles published in Intensive Care Med Retrieve available abstracts of 82 articles: HTML format

Single Articles

October 2025
1. MONNERET G, Lafon T, Gossez M, Evrard B, et al
   Monocyte HLA-DR expression in septic shock patients: insights from a 20-year real-world cohort of 1023 cases.
   Intensive Care Med. 2025;51:1820-1832.
   PubMed     Abstract available
   
   
   
2. PIRRACCHIO R, Fong N, Legrand M
   Heterogeneity in the response to a high vs low mean arterial pressure target in patients with septic shock a post hoc analysis of a randomized controlled trial.
   Intensive Care Med. 2025;51:1775-1783.
   PubMed     Abstract available
   
   
   August 2025
3. HALVORSEN P, Marks-Hultstrom M, Wallin E, Ahlstrom B, et al
   Post-sepsis recovery: perspectives on measuring what matters. Author's reply.
   Intensive Care Med. 2025 Aug 28. doi: 10.1007/s00134-025-08096.
   PubMed    
   
   
   
4. HALVORSEN P, Marks-Hultstrom M, Wallin E, Ahlstrom B, et al
   Challenges in assessing HRQoL after ICU sepsis: Author's reply.
   Intensive Care Med. 2025 Aug 19. doi: 10.1007/s00134-025-08083.
   PubMed    
   
   
   July 2025
5. CUMMINGS MJ, Lutwama JJ, Tomoiaga AS, Zhao M, et al
   Identification of transcriptomic sepsis endotypes in sub-Saharan Africa: derivation, validation, and global alignment in two Ugandan cohorts.
   Intensive Care Med. 2025 Jul 29. doi: 10.1007/s00134-025-08047.
   PubMed     Abstract available
   
   
   
6. WANG J, Wang Y, Guo J
   Challenges in assessing HRQoL after ICU sepsis.
   Intensive Care Med. 2025 Jul 28. doi: 10.1007/s00134-025-08051.
   PubMed    
   
   
   
7. SZARPAK L, Rybczynski B, Krupa A, Pruc M, et al
   Post-sepsis recovery: perspectives on measuring what matters.
   Intensive Care Med. 2025 Jul 24. doi: 10.1007/s00134-025-08055.
   PubMed    
   
   
   
8. ANNANE D, Briegel J, Seymour CW
   Corticosteroids in sepsis: certainties and shadows.
   Intensive Care Med. 2025 Jul 23. doi: 10.1007/s00134-025-08044.
   PubMed    
   
   
   
9. VAIDIE J, Demiselle J, Gabriel A, Guillon A, et al
   Effect of temporary suspension of chronic immunosuppressive drugs on day-90 mortality and ICU-acquired infections among critically Ill patients with solid organ transplant: a retrospective multicenter study.
   Intensive Care Med. 2025 Jul 16. doi: 10.1007/s00134-025-08024.
   PubMed     Abstract available
   
   
   
10. TABAH A, De Waele J, Ssi Yan Kai N, Aslan AT, et al
    Source control in bloodstream infections in patients with sepsis, septic shock, or requiring ICU admission: a scoping review with recommendations for standardizing research.
    Intensive Care Med. 2025 Jul 14. doi: 10.1007/s00134-025-08026.
    PubMed     Abstract available
    
    
    
11. DEMISELLE J, Ferrer R, Besen B
    Hemodynamic targets in the initial resuscitation of older patients with sepsis: time for a reappraisal?
    Intensive Care Med. 2025 Jul 3. doi: 10.1007/s00134-025-08010.
    PubMed    
    
    
    June 2025
12. HALVORSEN P, Marks-Hultstrom M, Wallin E, Ahlstrom B, et al
    Health-related quality of life and functional recovery after intensive care for sepsis in a national cohort.
    Intensive Care Med. 2025 Jun 23. doi: 10.1007/s00134-025-07998.
    PubMed     Abstract available
    
    
    
13. PAYEN D, Velho TR, Moita LF
    Beyond inflammation: the role of metabolic dysregulation in sepsis diagnosis and treatment.
    Intensive Care Med. 2025 Jun 3. doi: 10.1007/s00134-025-07948.
    PubMed    
    
    
    May 2025
14. KLOMPAS M, Lapao LV, Taylor SP
    Antibiotics for suspected sepsis: who and when?
    Intensive Care Med. 2025 May 19. doi: 10.1007/s00134-025-07940.
    PubMed    
    
    
    
15. ENDO A, Yamakawa K, Tagami T, Umemura Y, et al
    Efficacy of targeting high mean arterial pressure for older patients with septic shock (OPTPRESS): a multicentre, pragmatic, open-label, randomised controlled trial.
    Intensive Care Med. 2025;51:883-892.
    PubMed     Abstract available
    
    
    April 2025
16. HILL TM, Kerivan LT, Vilain KA, Windham S, et al
    Decision analysis model of rapid versus deferred antibiotic initiation in patients with suspected sepsis in the emergency department.
    Intensive Care Med. 2025 Apr 29. doi: 10.1007/s00134-025-07899.
    PubMed     Abstract available
    
    
    
17. DOUGLAS AO, Shelton KT
    Correspondence on "Management of adult sepsis in resource-limited settings: global expert consensus statements using a Delphi method".
    Intensive Care Med. 2025 Apr 3. doi: 10.1007/s00134-025-07858.
    PubMed    
    
    
    March 2025
18. ANTCLIFFE DB, Burrell A, Boyle AJ, Gordon AC, et al
    Sepsis subphenotypes, theragnostics and personalized sepsis care.
    Intensive Care Med. 2025 Mar 31. doi: 10.1007/s00134-025-07873.
    PubMed     Abstract available
    
    
    
19. MEKONTSO DESSAP A, AlShamsi F, Belletti A, De Backer D, et al
    European Society of Intensive Care Medicine (ESICM) 2025 clinical practice guideline on fluid therapy in adult critically ill patients: part 2-the volume of resuscitation fluids.
    Intensive Care Med. 2025 Mar 31. doi: 10.1007/s00134-025-07840.
    PubMed     Abstract available
    
    
    
20. KALIL AC, Povoa P, Leone M
    Subphenotypes and phenotypes to resolve sepsis heterogeneity: hype or hope?
    Intensive Care Med. 2025 Mar 6. doi: 10.1007/s00134-025-07828.
    PubMed    
    
    
    
21. GAJDOS L, Buetti N, Tabah A, Ruckly S, et al
    Shortening antibiotic therapy duration for hospital-acquired bloodstream infections in critically ill patients: a causal inference model from the international EUROBACT-2 database.
    Intensive Care Med. 2025;51:518-528.
    PubMed     Abstract available
    
    
    
22. ANTCLIFFE DB, Harte E, Hussain H, Jimenez B, et al
    Metabolic septic shock sub-phenotypes, stability over time and association with clinical outcome.
    Intensive Care Med. 2025;51:529-541.
    PubMed     Abstract available
    
    
    February 2025
23. SPRIET I, Gijsen M, Peetermans M, Debaveye Y, et al
    Continuous infusion of beta-lactam antibiotics in critically ill patients with sepsis: insights from daily clinical practice.
    Intensive Care Med. 2025 Feb 17. doi: 10.1007/s00134-025-07819.
    PubMed    
    
    
    January 2025
24. RYNNE J, Mosavie M, Masse MH, Menard J, et al
    Sepsis subtypes and differential treatment response to vitamin C: biological sub-study of the LOVIT trial.
    Intensive Care Med. 2025 Jan 7. doi: 10.1007/s00134-024-07733.
    PubMed     Abstract available
    
    
    
25. VIGNON P, Charron C, Legras A, Musset F, et al
    Left ventricular diastolic dysfunction is prevalent but not associated with mortality in patients with septic shock.
    Intensive Care Med. 2025;51:94-105.
    PubMed     Abstract available
    
    
    December 2024
26. THWAITES L, Nasa P, Abbenbroek B, Dat VQ, et al
    Management of adult sepsis in resource-limited settings: global expert consensus statements using a Delphi method.
    Intensive Care Med. 2024 Dec 23. doi: 10.1007/s00134-024-07735.
    PubMed     Abstract available
    
    
    
27. BLOOS F, Bogatsch H, Netea MG, Giamarellos-Bourboulis EJ, et al
    Effects of delayed consent on patient characteristics in adult patients with sepsis.
    Intensive Care Med. 2024 Dec 12. doi: 10.1007/s00134-024-07718.
    PubMed    
    
    
    
28. SCHAUMBURG T, Kohler N, Breitenstein Y, Kolbe-Busch S, et al
    EFFECT of daily antiseptic bathing with octenidine on ICU-acquired bacteremia and ICU-acquired multidrug-resistant organisms: a multicenter, cluster-randomized, double-blind, placebo-controlled, cross-over study.
    Intensive Care Med. 2024;50:2073-2082.
    PubMed     Abstract available
    
    
    
29. WALSHAM J, Hammond N, Blumenthal A, Cohen J, et al
    Fludrocortisone dose-response relationship in septic shock: a randomised phase II trial.
    Intensive Care Med. 2024;50:2050-2060.
    PubMed     Abstract available
    
    
    November 2024
30. MARTIN-LOECHES I, Singer M, Leone M
    Sepsis: key insights, future directions, and immediate goals. A review and expert opinion.
    Intensive Care Med. 2024 Nov 12. doi: 10.1007/s00134-024-07694.
    PubMed     Abstract available
    
    
    
31. RANZANI O, Annane D, Singer M
    Fludrocortisone with hydrocortisone in sepsis: new evidence in an ongoing debate.
    Intensive Care Med. 2024 Nov 12. doi: 10.1007/s00134-024-07699.
    PubMed    
    
    
    October 2024
32. BAILLIE JK, Angus D, Burnham K, Calandra T, et al
    Causal inference can lead us to modifiable mechanisms and informative archetypes in sepsis.
    Intensive Care Med. 2024 Oct 21. doi: 10.1007/s00134-024-07665.
    PubMed     Abstract available
    
    
    
33. BHAVANI SV, Spicer A, Sinha P, Malik A, et al
    Distinct immune profiles and clinical outcomes in sepsis subphenotypes based on temperature trajectories.
    Intensive Care Med. 2024 Oct 9. doi: 10.1007/s00134-024-07669.
    PubMed     Abstract available
    
    
    
34. REHBERG S, Frank S, Cerny V, Cihlar R, et al
    Landiolol for heart rate control in patients with septic shock and persistent tachycardia. A multicenter randomized clinical trial (Landi-SEP).
    Intensive Care Med. 2024;50:1622-1634.
    PubMed     Abstract available
    
    
    September 2024
35. BARTON G, Rickard CM, Roberts JA
    Continuous infusion of beta-lactam antibiotics in critically ill patients with sepsis: implementation considerations.
    Intensive Care Med. 2024 Sep 23. doi: 10.1007/s00134-024-07650.
    PubMed    
    
    
    
36. FREUND Y, Cancella de Abreu M, Bloom B
    Effect of the 1-h bundle on mortality in patients with suspected sepsis in the emergency department: faster is better for the sicker ones! Author's reply.
    Intensive Care Med. 2024 Sep 4. doi: 10.1007/s00134-024-07605.
    PubMed    
    
    
    
37. JOUFFROY R, Vivien B, Gueye P
    Effect of the 1-h bundle on mortality in patients with suspected sepsis in the emergency department: faster is better for the sicker ones!
    Intensive Care Med. 2024 Sep 4. doi: 10.1007/s00134-024-07594.
    PubMed    
    
    
    
38. GIRARDIS M, David S, Ferrer R, Helms J, et al
    Understanding, assessing and treating immune, endothelial and haemostasis dysfunctions in bacterial sepsis.
    Intensive Care Med. 2024 Sep 2. doi: 10.1007/s00134-024-07586.
    PubMed     Abstract available
    
    
    
39. AHLSTEDT C, Sivapalan P, Rooyackers O, Perner A, et al
    Complex interaction of infusion volumes and confounding factors with lactate clearance in septic shock. Author's reply.
    Intensive Care Med. 2024;50:1547-1548.
    PubMed    
    
    
    
40. TEJA B, Pereira TV, Law AC, Mazer CD, et al
    Effectiveness of fludrocortisone and hydrocortisone versus hydrocortisone alone in septic shock with and without pneumonia.
    Intensive Care Med. 2024;50:1535-1537.
    PubMed    
    
    
    
41. ISHII J, Ohshimo S, Nishikimi M, Kyo M, et al
    Complex interaction of infusion volumes and confounding factors with lactate clearance in septic shock.
    Intensive Care Med. 2024;50:1545-1546.
    PubMed    
    
    
    August 2024
42. FREUND Y, Cancella de Abreu M, Lebal S, Rousseau A, et al
    Correction: Effect of the 1-h bundle on mortality in patients with suspected sepsis in the emergency department: a stepped wedge cluster randomized clinical trial.
    Intensive Care Med. 2024 Aug 12. doi: 10.1007/s00134-024-07600.
    PubMed    
    
    
    June 2024
43. HELMS J, Povoa P, Jaber S
    Refining trial design in sepsis management: balancing realism with ideal outcomes.
    Intensive Care Med. 2024 Jun 26. doi: 10.1007/s00134-024-07521.
    PubMed    
    
    
    
44. FREUND Y, de Abreu MC, Lebal S, Rousseau A, et al
    Effect of the 1-h bundle on mortality in patients with suspected sepsis in the emergency department: a stepped wedge cluster randomized clinical trial.
    Intensive Care Med. 2024 Jun 24. doi: 10.1007/s00134-024-07509.
    PubMed     Abstract available
    
    
    
45. MEZIANI F, Iba T, Levy JH, Helms J, et al
    Sepsis-induced coagulopathy: a matter of timeline.
    Intensive Care Med. 2024 Jun 10. doi: 10.1007/s00134-024-07507.
    PubMed    
    
    
    
46. MONGARDON N, Vincent JL
    Outcome of hospital-acquired bloodstream infection: interplay between bacteria, host, and healthcare system organization.
    Intensive Care Med. 2024;50:925-927.
    PubMed    
    
    
    
47. BUETTI N, Tabah A, Setti N, Ruckly S, et al
    The role of centre and country factors on process and outcome indicators in critically ill patients with hospital-acquired bloodstream infections.
    Intensive Care Med. 2024;50:873-889.
    PubMed     Abstract available
    
    
    May 2024
48. NEDEL WL, Portela LV
    Lactate levels in sepsis: don't forget the mitochondria.
    Intensive Care Med. 2024 May 23. doi: 10.1007/s00134-024-07475.
    PubMed    
    
    
    
49. ARABI YM, Belley-Cote E, Carsetti A, De Backer D, et al
    European Society of Intensive Care Medicine clinical practice guideline on fluid therapy in adult critically ill patients. Part 1: the choice of resuscitation fluids.
    Intensive Care Med. 2024 May 21. doi: 10.1007/s00134-024-07369.
    PubMed     Abstract available
    
    
    
50. LEONE M, Nielsen ND, Russell L
    Ten tips on sepsis-induced thrombocytopenia.
    Intensive Care Med. 2024 May 13. doi: 10.1007/s00134-024-07478.
    PubMed    
    
    
    
51. ZIMMERMANN T, Brealey D, Singer M
    Diagnosing sepsis: where we're at and where we're going.
    Intensive Care Med. 2024 May 2. doi: 10.1007/s00134-024-07428.
    PubMed    
    
    
    
52. AHLSTEDT C, Sivapalan P, Kriz M, Jacobson G, et al
    Effects of restrictive fluid therapy on the time to resolution of hyperlactatemia in ICU patients with septic shock. A secondary post hoc analysis of the CLASSIC randomized trial.
    Intensive Care Med. 2024;50:678-686.
    PubMed     Abstract available
    
    
    April 2024
53. CHAI MG, Tu Q, Cotta MO, Bauer MJ, et al
    Correction: Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis.
    Intensive Care Med. 2024 Apr 2. doi: 10.1007/s00134-024-07393.
    PubMed    
    
    
    
54. ZHAO Y, Zang B, Wang Q
    The effectiveness of alkaline phosphatase in sepsis-associated acute kidney injury.
    Intensive Care Med. 2024 Apr 2. doi: 10.1007/s00134-024-07392.
    PubMed    
    
    
    
55. HERNANDEZ G, Carmona P, Ait-Oufella H
    Monitoring capillary refill time in septic shock.
    Intensive Care Med. 2024;50:580-582.
    PubMed    
    
    
    
56. KATTAN E, Ibarra-Estrada M, Jung C
    Knowing the ropes of vasopressor dosing: a focus on norepinephrine.
    Intensive Care Med. 2024;50:587-589.
    PubMed    
    
    
    March 2024
57. CHAI GG, Tu Q, Cotta MO, Bauer MJ, et al
    Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis.
    Intensive Care Med. 2024 Mar 13. doi: 10.1007/s00134-024-07353.
    PubMed     Abstract available
    
    
    
58. PICKKERS P, Angus DC, Bass K, Bellomo R, et al
    Correction: Phase-3 trial of recombinant human alkaline phosphatase for patients with sepsis-associated acute kidney injury (REVIVAL).
    Intensive Care Med. 2024 Mar 4. doi: 10.1007/s00134-024-07357.
    PubMed    
    
    
    
59. AHLSTROM B, Larsson IM, Strandberg G, Lipcsey M, et al
    Association of sepsis with long-term mortality and causes of death in the Swedish intensive care cohort.
    Intensive Care Med. 2024 Mar 4. doi: 10.1007/s00134-024-07370.
    PubMed    
    
    
    
60. DE BACKER D, Hajjar L, Monnet X
    Vasoconstriction in septic shock.
    Intensive Care Med. 2024;50:459-462.
    PubMed    
    
    
    
61. KREITMANN L, Helms J, Martin-Loeches I, Salluh J, et al
    ICU-acquired infections in immunocompromised patients.
    Intensive Care Med. 2024;50:332-349.
    PubMed     Abstract available
    
    
    January 2024
62. PROWLE JR, Bagshaw SM, Forni LG
    Tackling sepsis-associated AKI: are there any chances of REVIVAL with new approaches?
    Intensive Care Med. 2024 Jan 10. doi: 10.1007/s00134-023-07294.
    PubMed    
    
    
    
63. PICKKERS P, Angus DC, Bass K, Bellomo R, et al
    Phase-3 trial of recombinant human alkaline phosphatase for patients with sepsis-associated acute kidney injury (REVIVAL).
    Intensive Care Med. 2024 Jan 3. doi: 10.1007/s00134-023-07271.
    PubMed     Abstract available
    
    
    
64. ZAMPIERI FG, Machado FR, Veiga VC, Azevedo LCP, et al
    Determinants of fluid use and the association between volume of fluid used and effect of balanced solutions on mortality in critically ill patients: a secondary analysis of the BaSICS trial.
    Intensive Care Med. 2024;50:79-89.
    PubMed     Abstract available
    
    
    November 2023
65. BALIK M, Maly M, Brozek T, Rulisek J, et al
    Propafenone versus amiodarone for supraventricular arrhythmias in septic shock: a randomised controlled trial.
    Intensive Care Med. 2023;49:1283-1292.
    PubMed     Abstract available
    
    
    October 2023
66. FOWLER C, Scordo M, Chawla S
    The EAS(E)IX of predicting sepsis after allogeneic hematopoietic cell transplantation.
    Intensive Care Med. 2023 Oct 24. doi: 10.1007/s00134-023-07242.
    PubMed    
    
    
    
67. VAN AMSTEL RBE, Kennedy JN, Scicluna BP, Bos LDJ, et al
    Uncovering heterogeneity in sepsis: a comparative analysis of subphenotypes.
    Intensive Care Med. 2023 Oct 18. doi: 10.1007/s00134-023-07239.
    PubMed     Abstract available
    
    
    
68. ZHANG Z, Chen L, Liu X, Yang J, et al
    Exploring disease axes as an alternative to distinct clusters for characterizing sepsis heterogeneity.
    Intensive Care Med. 2023 Oct 4. doi: 10.1007/s00134-023-07226.
    PubMed     Abstract available
    
    
    September 2023
69. WHITE KC, Laupland KB, Tabah A, Ramanan M, et al
    Details and the devil within: the case of sepsis associated AKI. Author's reply.
    Intensive Care Med. 2023 Sep 10. doi: 10.1007/s00134-023-07209.
    PubMed    
    
    
    August 2023
70. GOMEZ H, Zarbock A
    Details and the devil within - the case of sepsis associated acute kidney injury.
    Intensive Care Med. 2023 Aug 31. doi: 10.1007/s00134-023-07204.
    PubMed    
    
    
    
71. WHITE KC, Laupland KB, Tabah A, Ramanan M, et al
    Clinical implications of urine output-based sepsis-associated acute kidney injury. Author's reply.
    Intensive Care Med. 2023 Aug 28. doi: 10.1007/s00134-023-07205.
    PubMed    
    
    
    
72. CLAURE-DEL GRANADO R, James MT, Legrand M
    Tackling sepsis-associated acute kidney injury using routinely collected data.
    Intensive Care Med. 2023 Aug 28. doi: 10.1007/s00134-023-07200.
    PubMed    
    
    
    
73. GIAMARELLOS-BOURBOULIS EJ, Zinkernagel AS, De Robertis E, Azoulay E, et al
    Correction: Sepsis, a call for inclusion in the work plan of the European Center for Disease Prevention and Control.
    Intensive Care Med. 2023 Aug 24. doi: 10.1007/s00134-023-07197.
    PubMed    
    
    
    
74. KORELL F, DeFilipp Z, Schreck N, Luft T, et al
    Validation of pre-conditioning EASIX for prediction of sepsis after allogeneic stem cell transplantation.
    Intensive Care Med. 2023 Aug 23. doi: 10.1007/s00134-023-07193.
    PubMed    
    
    
    
75. KASUGAI D, Nakashima T, Goto T
    Clinical implications of urine output-based sepsis-associated acute kidney injury.
    Intensive Care Med. 2023 Aug 21. doi: 10.1007/s00134-023-07190.
    PubMed    
    
    
    
76. GIAMARELLOS-BOURBOULIS EJ, Zinkernagel AS, De Robertis E, Azoulay E, et al
    Sepsis, a call for inclusion in the work plan of the European Center for Disease Prevention and Control.
    Intensive Care Med. 2023 Aug 1. doi: 10.1007/s00134-023-07127.
    PubMed    
    
    
    July 2023
77. REILLY JP, Zhao Z, Shashaty MGS, Koyama T, et al
    Exposure to ambient air pollutants and acute respiratory distress syndrome risk in sepsis.
    Intensive Care Med. 2023 Jul 20. doi: 10.1007/s00134-023-07148.
    PubMed     Abstract available
    
    
    
78. WHITE KC, Serpa-Neto A, Hurford R, Clement P, et al
    Sepsis-associated acute kidney injury in the intensive care unit: incidence, patient characteristics, timing, trajectory, treatment, and associated outcomes. A multicenter, observational study.
    Intensive Care Med. 2023 Jul 11. doi: 10.1007/s00134-023-07138.
    PubMed     Abstract available
    
    
    
79. KJAER MN, Meyhoff TS, Sivapalan P, Granholm A, et al
    Long-term effects of restriction of intravenous fluid in adult ICU patients with septic shock.
    Intensive Care Med. 2023;49:820-830.
    PubMed     Abstract available
    
    
    June 2023
80. ZHANG C, Zhang X, Sun Z, Liu X, et al
    MetaSepsisBase: a biomarker database for systems biological analysis and personalized diagnosis of heterogeneous human sepsis.
    Intensive Care Med. 2023 Jun 17. doi: 10.1007/s00134-023-07126.
    PubMed    
    
    
    
81. BRUNO RR, Wollborn J, Fengler K, Flick M, et al
    Direct assessment of microcirculation in shock: a randomized-controlled multicenter study.
    Intensive Care Med. 2023;49:645-655.
    PubMed     Abstract available
    
    
    April 2023
82. BOLDT J, Muller M, Kuhn D, Linke LC, et al
    Retraction Note: Circulating adhesion molecules in the critically ill: A comparison between trauma and sepsis patients.
    Intensive Care Med. 2023 Apr 4. doi: 10.1007/s00134-023-07055.
    PubMed    
    
    

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