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COVID-19: Daily Top 10 Papers


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Articles published in Intensive Care Med

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Single Articles


    March 2021
  1. PELLEGRINI JAS, Schwarz P, Parolo E, Cremonese RV, et al
    All that glitters is not gold: an unusual presentation of S. aureus sepsis during ECMO.
    Intensive Care Med. 2021 Mar 21. pii: 10.1007/s00134-021-06366.
    PubMed    


  2. DAVID S, Bode C, Putensen C, Welte T, et al
    Adjuvant therapeutic plasma exchange in septic shock.
    Intensive Care Med. 2021;47:352-354.
    PubMed    


    January 2021
  3. BUETTI N, Ruckly S, de Montmollin E, Reignier J, et al
    COVID-19 increased the risk of ICU-acquired bloodstream infections: a case-cohort study from the multicentric OUTCOMEREA network.
    Intensive Care Med. 2021 Jan 27. pii: 10.1007/s00134-021-06346.
    PubMed     Abstract available


    September 2020
  4. FUJII T, Fowler R, Vincent JL
    Vitamin C and thiamine for sepsis: time to go back to fundamental principles.
    Intensive Care Med. 2020 Sep 18. pii: 10.1007/s00134-020-06242.
    PubMed    


    August 2020

  5. Could lung bacterial dysbiosis predict ICU mortality in patients with extra-pulmonary sepsis? A proof-of-concept study.
    Intensive Care Med. 2020 Aug 7. pii: 10.1007/s00134-020-06190.
    PubMed    


    July 2020
  6. AURIEMMA CL, Delucchi K, Liu KD, Calfee CS, et al
    The attributable mortality of acute respiratory distress syndrome.
    Intensive Care Med. 2020;46:1510-1511.
    PubMed    


  7. DE GROOTH HJ, Tuinman PR, Girbes ARJ
    The attributable mortality of acute respiratory distress syndrome.
    Intensive Care Med. 2020;46:1508-1509.
    PubMed    


    June 2020
  8. LANE DJ, Wunsch H, Saskin R, Cheskes S, et al
    Correction to: Epidemiology and patient predictors of infection and sepsis in the prehospital setting.
    Intensive Care Med. 2020 Jun 30. pii: 10.1007/s00134-020-06164.
    PubMed     Abstract available


  9. MARKWART R, Saito H, Harder T, Tomczyk S, et al
    Epidemiology and burden of sepsis acquired in hospitals and intensive care units: a systematic review and meta-analysis.
    Intensive Care Med. 2020 Jun 26. pii: 10.1007/s00134-020-06106.
    PubMed     Abstract available


  10. FLEISCHMANN-STRUZEK C, Mellhammar L, Rose N, Cassini A, et al
    Incidence and mortality of hospital- and ICU-treated sepsis: results from an updated and expanded systematic review and meta-analysis.
    Intensive Care Med. 2020 Jun 22. pii: 10.1007/s00134-020-06151.
    PubMed     Abstract available


  11. TISSIERES P, Peters MJ, Kissoon N, Weiss SL, et al
    Might the surviving sepsis campaign international guidelines be less confusing? Authors' reply.
    Intensive Care Med. 2020 Jun 22. pii: 10.1007/s00134-020-06158.
    PubMed    


  12. UHEL F, Peters-Sengers H, Falahi F, Scicluna BP, et al
    Mortality and host response aberrations associated with transient and persistent acute kidney injury in critically ill patients with sepsis: a prospective cohort study.
    Intensive Care Med. 2020 Jun 8. pii: 10.1007/s00134-020-06119.
    PubMed     Abstract available


  13. MONNERET G, Cour M, Viel S, Venet F, et al
    Coronavirus disease 2019 as a particular sepsis: a 2-week follow-up of standard immunological parameters in critically ill patients.
    Intensive Care Med. 2020 Jun 2. pii: 10.1007/s00134-020-06123.
    PubMed    


    May 2020
  14. LANE DJ, Wunsch H, Saskin R, Cheskes S, et al
    Epidemiology and patient predictors of infection and sepsis in the prehospital setting.
    Intensive Care Med. 2020 May 28. pii: 10.1007/s00134-020-06093.
    PubMed     Abstract available


  15. BRIASSOULIS G, Briassoulis P, Miliaraki M, Ilia S, et al
    Might the pediatric surviving sepsis campaign international guidelines be less confusing?
    Intensive Care Med. 2020 May 25. pii: 10.1007/s00134-020-06108.
    PubMed    


  16. REN D, Ren C, Yao RQ, Feng YW, et al
    Clinical features and development of sepsis in patients infected with SARS-CoV-2: a retrospective analysis of 150 cases outside Wuhan, China.
    Intensive Care Med. 2020 May 15. pii: 10.1007/s00134-020-06084.
    PubMed    


  17. REINHART K, Daniels RD, Schwarzkopf D, Kissoon N, et al
    Sepsis hysteria: facts versus fiction.
    Intensive Care Med. 2020 May 4. pii: 10.1007/s00134-020-06001.
    PubMed    


    April 2020
  18. HELMS J, Perner A
    Focus on sepsis.
    Intensive Care Med. 2020 Apr 23. pii: 10.1007/s00134-020-06038.
    PubMed    


  19. STOLK RF, Kox M, Pickkers P
    Noradrenaline drives immunosuppression in sepsis: clinical consequences.
    Intensive Care Med. 2020 Apr 8. pii: 10.1007/s00134-020-06025.
    PubMed    


    March 2020
  20. ALHAZZANI W, Moller MH, Arabi YM, Loeb M, et al
    Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID-19).
    Intensive Care Med. 2020 Mar 28. pii: 10.1007/s00134-020-06022.
    PubMed     Abstract available


  21. AURIEMMA CL, Zhuo H, Delucchi K, Deiss T, et al
    Acute respiratory distress syndrome-attributable mortality in critically ill patients with sepsis.
    Intensive Care Med. 2020 Mar 23. pii: 10.1007/s00134-020-06010.
    PubMed     Abstract available


  22. ELIZABETH WILCOX M, Donnelly JP, Lone NI
    Correction to: Understanding gender disparities in outcomes after sepsis.
    Intensive Care Med. 2020 Mar 13. pii: 10.1007/s00134-020-06006.
    PubMed     Abstract available


  23. ZHANG W
    Imaging changes in severe COVID-19 pneumonia.
    Intensive Care Med. 2020 Mar 3. pii: 10.1007/s00134-020-05976.
    PubMed    


    February 2020
  24. BRANT EB, Martin-Gill C, Callaway CW, Angus DC, et al
    Prehospital identification of community sepsis using biomarkers of host response.
    Intensive Care Med. 2020 Feb 24. pii: 10.1007/s00134-020-05975.
    PubMed    


  25. HERNANDEZ G, Kattan E, Ospina-Tascon G, Bakker J, et al
    Capillary refill time status could identify different clinical phenotypes among septic shock patients fulfilling Sepsis-3 criteria: a post hoc analysis of ANDROMEDA-SHOCK trial.
    Intensive Care Med. 2020 Feb 19. pii: 10.1007/s00134-020-05960.
    PubMed    


  26. ELIZABETH WILCOX M, Donnelly JP, Lone NI
    Understanding gender disparities in outcomes after sepsis.
    Intensive Care Med. 2020 Feb 18. pii: 10.1007/s00134-020-05961.
    PubMed    


  27. TAYLOR MD, Tibby SM
    Sometimes more is not always better: ScvO2 monitoring in pediatric sepsis.
    Intensive Care Med. 2020 Feb 11. pii: 10.1007/s00134-020-05946.
    PubMed    


  28. GARNACHO-MONTERO J, Martin-Loeches I
    Clinical management of sepsis can be improved by artificial intelligence: no.
    Intensive Care Med. 2020 Feb 3. pii: 10.1007/s00134-020-05947.
    PubMed    


  29. WEISS SL, Peters MJ, Alhazzani W, Agus MSD, et al
    Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children.
    Intensive Care Med. 2020;46.
    PubMed     Abstract available


  30. WEISS SL, Peters MJ, Alhazzani W, Agus MSD, et al
    Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children.
    Intensive Care Med. 2020;46.
    PubMed    


  31. TIMSIT JF, Ruppe E, Barbier F, Tabah A, et al
    Bloodstream infections in critically ill patients: an expert statement.
    Intensive Care Med. 2020;46:266-284.
    PubMed     Abstract available


  32. RELLO J, Campogiani L, Eshwara VK
    Understanding resistance in enterococcal infections.
    Intensive Care Med. 2020;46:353-356.
    PubMed    


    January 2020
  33. SHANKAR-HARI M, Saha R, Wilson J, Prescott HC, et al
    Rate and risk factors for rehospitalisation in sepsis survivors: systematic review and meta-analysis.
    Intensive Care Med. 2020 Jan 23. pii: 10.1007/s00134-019-05908.
    PubMed     Abstract available


  34. SUNDEN-CULLBERG J, Nilsson A, Inghammar M
    Sex-based differences in ED management of critically ill patients with sepsis: a nationwide cohort study.
    Intensive Care Med. 2020 Jan 23. pii: 10.1007/s00134-019-05910.
    PubMed     Abstract available


  35. FLEUREN LM, Klausch TLT, Zwager CL, Schoonmade LJ, et al
    Machine learning for the prediction of sepsis: a systematic review and meta-analysis of diagnostic test accuracy.
    Intensive Care Med. 2020 Jan 21. pii: 10.1007/s00134-019-05872.
    PubMed     Abstract available


  36. SANKAR J, Singh M, Kumar K, Sankar MJ, et al
    'Intermittent' versus 'continuous' ScvO2 monitoring in children with septic shock: a randomised, non-inferiority trial.
    Intensive Care Med. 2020;46:82-92.
    PubMed     Abstract available


  37. BOSCH NA, Teja B, Wunsch H, Walkey AJ, et al
    Characterization and validation of a novel measure of septic shock severity.
    Intensive Care Med. 2020;46:135-137.
    PubMed    


    December 2019
  38. KOMOROWSKI M
    Clinical management of sepsis can be improved by artificial intelligence: yes.
    Intensive Care Med. 2019 Dec 13. pii: 10.1007/s00134-019-05898.
    PubMed    


    November 2019
  39. PERNER A, De Jong A, Shankar-Hari M
    Trials on oxygen supplementation in sepsis: better late than never.
    Intensive Care Med. 2019 Nov 26. pii: 10.1007/s00134-019-05874.
    PubMed    


  40. YOUNG P, Mackle D, Bellomo R, Bailey M, et al
    Conservative oxygen therapy for mechanically ventilated adults with sepsis: a post hoc analysis of data from the intensive care unit randomized trial comparing two approaches to oxygen therapy (ICU-ROX).
    Intensive Care Med. 2019 Nov 20. pii: 10.1007/s00134-019-05857.
    PubMed     Abstract available


    October 2019
  41. BLOT S, Antonelli M, Arvaniti K, Blot K, et al
    Epidemiology of intra-abdominal infection and sepsis in critically ill patients: "AbSeS", a multinational observational cohort study and ESICM Trials Group Project.
    Intensive Care Med. 2019 Oct 29. pii: 10.1007/s00134-019-05819.
    PubMed     Abstract available


  42. SHANKAR-HARI M, Fish M, Azoulay E
    Should we consider blocking the inhibitory immune checkpoint molecules for treating T cell exhaustion in sepsis?
    Intensive Care Med. 2019 Oct 28. pii: 10.1007/s00134-019-05814.
    PubMed    


  43. HOTCHKISS RS, Colston E, Yende S, Crouser ED, et al
    Immune checkpoint inhibition in sepsis: a Phase 1b randomized study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of nivolumab.
    Intensive Care Med. 2019;45:1360-1371.
    PubMed     Abstract available


    September 2019
  44. KLEINPELL R, Blot S, Boulanger C, Fulbrook P, et al
    International critical care nursing considerations and quality indicators for the 2017 surviving sepsis campaign guidelines.
    Intensive Care Med. 2019 Sep 18. pii: 10.1007/s00134-019-05780.
    PubMed    


  45. VAN DER WEERT S, Lansink PJ, Vermeijden JW, Cornet AD, et al
    Rare metastatic seeding: endogenous endophtalmitis in Staphylococcus aureus sepsis.
    Intensive Care Med. 2019 Sep 3. pii: 10.1007/s00134-019-05762.
    PubMed    


    August 2019
  46. DARGENT A, Pais De Barros JP, Ksiazek E, Fournel I, et al
    Improved quantification of plasma lipopolysaccharide (LPS) burden in sepsis using 3-hydroxy myristate (3HM): a cohort study.
    Intensive Care Med. 2019 Aug 26. pii: 10.1007/s00134-019-05749.
    PubMed    


  47. SCHETZ M, Bein T
    When more could be industry-driven: the case of the extracorporeal treatment of sepsis.
    Intensive Care Med. 2019 Aug 13. pii: 10.1007/s00134-019-05728.
    PubMed    


    July 2019
  48. MOLLER MH, Alhazzani W, Shankar-Hari M
    Focus on sepsis.
    Intensive Care Med. 2019 Jul 2. pii: 10.1007/s00134-019-05680.
    PubMed    


  49. CASTELA FORTE J, Perner A, van der Horst ICC
    The use of clustering algorithms in critical care research to unravel patient heterogeneity.
    Intensive Care Med. 2019;45:1025-1028.
    PubMed    


    June 2019
  50. BLOT S, Poulakou G, Timsit JF
    Catheter-associated bloodstream infection rates: how low can you go?
    Intensive Care Med. 2019;45:896-897.
    PubMed    


  51. YOUNG PJ, Delaney A, Venkatesh B
    Vasopressin in septic shock: what we know and where to next?
    Intensive Care Med. 2019;45:902-903.
    PubMed    


  52. NAGENDRAN M, Russell JA, Walley KR, Brett SJ, et al
    Vasopressin in septic shock: an individual patient data meta-analysis of randomised controlled trials.
    Intensive Care Med. 2019;45:844-855.
    PubMed     Abstract available


  53. EGGIMANN P, Pagani JL, Dupuis-Lozeron E, Ms BE, et al
    Sustained reduction of catheter-associated bloodstream infections with enhancement of catheter bundle by chlorhexidine dressings over 11 years.
    Intensive Care Med. 2019;45:823-833.
    PubMed     Abstract available


  54. MARTIN-LOECHES I, Antonelli M, Cuenca-Estrella M, Dimopoulos G, et al
    ESICM/ESCMID task force on practical management of invasive candidiasis in critically ill patients.
    Intensive Care Med. 2019;45:789-805.
    PubMed     Abstract available


    May 2019
  55. DUCLOS G, Cantaloube M, Medam S, Resseguier N, et al
    Preliminary results of synergy between norepinephrine and terlipressin during septic shock.
    Intensive Care Med. 2019;45:730-732.
    PubMed    


    April 2019
  56. DE BACKER D, Cecconi M, Lipman J, Machado F, et al
    Challenges in the management of septic shock: a narrative review.
    Intensive Care Med. 2019;45:420-433.
    PubMed     Abstract available


  57. PAPAROUPA M, Yan Y, Moller M, Schuppert F, et al
    Nasogastric tube ending in the right pleura of an intubated patient.
    Intensive Care Med. 2019;45:523-524.
    PubMed    


    February 2019
  58. CLERE-JEHL R, Merdji H, Derhy D, Helms J, et al
    Blindness as an uncommon complication of Streptococcus pneumoniae systemic infection.
    Intensive Care Med. 2019;45:263-265.
    PubMed    


  59. BOS LDJ, Azoulay E, Martin-Loeches I
    Future of the ICU: finding treatable needles in the data haystack.
    Intensive Care Med. 2019;45:240-242.
    PubMed    


    January 2019
  60. BRIASSOULIS G, Briassoulis P, Miliaraki M, Ilia S, et al
    Biomarker cruises in sepsis: who is the CAPTAIN? Discussion on "Circulating biomarkers may be unable to detect infection at the early phase of sepsis in ICU patients: the CAPTAIN prospective multicenter cohort study".
    Intensive Care Med. 2019 Jan 7. pii: 10.1007/s00134-018-5451.
    PubMed    


    December 2018
  61. PICKKERS P, Russell JA
    Treatment with a polymyxin B filter to capture endotoxin in sepsis patients: is there a signal for therapeutic efficacy?
    Intensive Care Med. 2018 Dec 3. pii: 10.1007/s00134-018-5481.
    PubMed    


  62. SWENSON ER, Porcher R, Piagnerelli M
    Iron deficiency and infection: another pathway to explore in critically ill patients?
    Intensive Care Med. 2018;44:2260-2262.
    PubMed    


    November 2018
  63. MALLAT J, Reddi BJ
    Do not abandon monitoring the central venous pressure during fluid resuscitation of septic shock patients.
    Intensive Care Med. 2018;44:2012-2013.
    PubMed    


    October 2018
  64. MACDONALD SPJ, Keijzers G, Taylor DM, Kinnear F, et al
    Restricted fluid resuscitation in suspected sepsis associated hypotension (REFRESH): a pilot randomised controlled trial.
    Intensive Care Med. 2018 Oct 31. pii: 10.1007/s00134-018-5433.
    PubMed     Abstract available


  65. REILLY JP, Wang F, Jones TK, Palakshappa JA, et al
    Plasma angiopoietin-2 as a potential causal marker in sepsis-associated ARDS development: evidence from Mendelian randomization and mediation analysis.
    Intensive Care Med. 2018 Oct 21. pii: 10.1007/s00134-018-5328.
    PubMed     Abstract available


  66. TIMSIT JF, Ruppe E, Ferrer R
    Focus on sepsis: new concepts and findings in sepsis care.
    Intensive Care Med. 2018 Oct 10. pii: 10.1007/s00134-018-5406.
    PubMed    


  67. SHANKAR-HARI M, Datta D, Wilson J, Assi V, et al
    Early PREdiction of sepsis using leukocyte surface biomarkers: the ExPRES-sepsis cohort study.
    Intensive Care Med. 2018 Oct 5. pii: 10.1007/s00134-018-5389.
    PubMed     Abstract available


  68. SINHA P, Delucchi KL, Thompson BT, McAuley DF, et al
    Latent class analysis of ARDS subphenotypes: a secondary analysis of the statins for acutely injured lungs from sepsis (SAILS) study.
    Intensive Care Med. 2018 Oct 5. pii: 10.1007/s00134-018-5378.
    PubMed     Abstract available


  69. FLEISCHMANN-STRUZEK C, Mikolajetz A, Schwarzkopf D, Cohen J, et al
    Challenges in assessing the burden of sepsis and understanding the inequalities of sepsis outcomes between National Health Systems: secular trends in sepsis and infection incidence and mortality in Germany.
    Intensive Care Med. 2018 Oct 4. pii: 10.1007/s00134-018-5377.
    PubMed     Abstract available


    September 2018
  70. KAPLAN JM, Zingarelli B, Krallman K, Tang Girdwood S, et al
    Phase 1 safety and pharmacokinetic study on the use of pioglitazone in critically ill patients with sepsis: a randomized clinical trial.
    Intensive Care Med. 2018 Sep 25. pii: 10.1007/s00134-018-5374.
    PubMed    


  71. LAVILLEGRAND JR, Dumas G, Bige N, Zafimahazo D, et al
    Should we treat mild hypotension in septic patients in the absence of peripheral tissue hypoperfusion?
    Intensive Care Med. 2018;44:1593-1594.
    PubMed    


    August 2018
  72. LUECK C, Stadler M, Koenecke C, Hoeper MM, et al
    Improved short- and long-term outcome of allogeneic stem cell recipients admitted to the intensive care unit: a retrospective longitudinal analysis of 942 patients.
    Intensive Care Med. 2018 Aug 23. pii: 10.1007/s00134-018-5347.
    PubMed     Abstract available


  73. LAW AC, Sahetya S, Walkey AJ, Delaney A, et al
    Low-dose corticosteroids and septic shock resolution: implications for randomized trial design?
    Intensive Care Med. 2018;44:1366-1367.
    PubMed    


  74. MOHUS RM, Paulsen J, Gustad L, Askim A, et al
    Association of iron status with the risk of bloodstream infections: results from the prospective population-based HUNT Study in Norway.
    Intensive Care Med. 2018;44:1276-1283.
    PubMed     Abstract available


    July 2018
  75. KERRIGAN SW, Martin-Loeches I
    Public awareness of sepsis is still poor: we need to do more.
    Intensive Care Med. 2018 Jul 19. pii: 10.1007/s00134-018-5307.
    PubMed    


  76. HODGSON CL, Walsh TS, Lone N
    The long road home: are outcomes different for patients with sepsis?
    Intensive Care Med. 2018 Jul 18. pii: 10.1007/s00134-018-5301.
    PubMed    


  77. COOPERSMITH CM, De Backer D, Deutschman CS, Ferrer R, et al
    Surviving sepsis campaign: research priorities for sepsis and septic shock.
    Intensive Care Med. 2018 Jul 3. pii: 10.1007/s00134-018-5175.
    PubMed     Abstract available


  78. RYGARD SL, Butler E, Granholm A, Moller MH, et al
    Low-dose corticosteroids for adult patients with septic shock: a systematic review with meta-analysis and trial sequential analysis.
    Intensive Care Med. 2018;44:1003-1016.
    PubMed     Abstract available


    June 2018
  79. PARLATO M, Philippart F, Rouquette A, Moucadel V, et al
    Circulating biomarkers may be unable to detect infection at the early phase of sepsis in ICU patients: the CAPTAIN prospective multicenter cohort study.
    Intensive Care Med. 2018 Jun 30. pii: 10.1007/s00134-018-5228.
    PubMed     Abstract available


  80. THOMPSON K, Taylor C, Jan S, Li Q, et al
    Health-related outcomes of critically ill patients with and without sepsis.
    Intensive Care Med. 2018 Jun 27. pii: 10.1007/s00134-018-5274.
    PubMed     Abstract available


  81. SINGH K, Mayo P
    Transthoracic echocardiography and mortality in sepsis: are we there yet?
    Intensive Care Med. 2018 Jun 25. pii: 10.1007/s00134-018-5261.
    PubMed    


  82. MAHLA RS, Vincent JL, Sakr Y
    Sepsis is a global burden to human health: incidences are underrepresented : Discussion on " Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)".
    Intensive Care Med. 2018 Jun 19. pii: 10.1007/s00134-018-5239.
    PubMed    


  83. TEXTORIS J, Gordon AC
    Sepsis: who will shoot first? Pharma or diagnostics?
    Intensive Care Med. 2018 Jun 14. pii: 10.1007/s00134-018-5234.
    PubMed    


  84. ANNANE D, Ouanes-Besbes L, de Backer D, DU B, et al
    A global perspective on vasoactive agents in shock.
    Intensive Care Med. 2018;44:833-846.
    PubMed     Abstract available


    May 2018
  85. WENG L, Zeng XY, Yin P, Wang LJ, et al
    Sepsis-related mortality in China: a descriptive analysis.
    Intensive Care Med. 2018 May 30. pii: 10.1007/s00134-018-5203.
    PubMed     Abstract available


  86. FENG M, McSparron JI, Kien DT, Stone DJ, et al
    Transthoracic echocardiography and mortality in sepsis: analysis of the MIMIC-III database.
    Intensive Care Med. 2018 May 28. pii: 10.1007/s00134-018-5208.
    PubMed     Abstract available


  87. MONNIER-CHOLLEY L, Roux A, Pacanowski J, Arrive L, et al
    Myocardial calcifications following sepsis.
    Intensive Care Med. 2018 May 14. pii: 10.1007/s00134-018-5168.
    PubMed    


  88. HERNANDEZ G, Bellomo R, Bakker J
    The ten pitfalls of lactate clearance in sepsis.
    Intensive Care Med. 2018 May 12. pii: 10.1007/s00134-018-5213.
    PubMed    


  89. MANKOWSKI RT, Yende S, Angus DC
    Long-term impact of sepsis on cardiovascular health.
    Intensive Care Med. 2018 May 8. pii: 10.1007/s00134-018-5173.
    PubMed    


  90. HARIRI G, Joffre J, Deryckere S, Bige N, et al
    Albumin infusion improves endothelial function in septic shock patients: a pilot study.
    Intensive Care Med. 2018;44:669-671.
    PubMed    


    April 2018
  91. PERNER A, Cecconi M, Cronhjort M, Darmon M, et al
    Expert statement for the management of hypovolemia in sepsis.
    Intensive Care Med. 2018 Apr 25. pii: 10.1007/s00134-018-5177.
    PubMed     Abstract available


  92. LEVY MM, Evans LE, Rhodes A
    The Surviving Sepsis Campaign Bundle: 2018 update.
    Intensive Care Med. 2018 Apr 19. pii: 10.1007/s00134-018-5085.
    PubMed    


  93. ISHII J, Ohshimo S, Shime N, Lamontagne F, et al
    Target blood pressure for septic and vasodilatory shock: what is optimal?
    Intensive Care Med. 2018;44:548-549.
    PubMed    


  94. ARGENT AC, Chisti MJ, Ranjit S
    What's new in PICU in resource limited settings?
    Intensive Care Med. 2018;44:467-469.
    PubMed    


  95. COLOMBO J, Elzi L, Treglia G, Perren A, et al
    Light in the dark: (18)F-FDG PET/CT in Staphylococcus aureus bacteremia of unknown origin.
    Intensive Care Med. 2018;44:488-489.
    PubMed    


    March 2018
  96. RUSSELL JA, Spronk P, Walley KR
    Using multiple 'omics strategies for novel therapies in sepsis.
    Intensive Care Med. 2018 Mar 15. pii: 10.1007/s00134-018-5122.
    PubMed    


  97. SAITO H, Kilpatrick C, Pittet D
    The 2018 World Health Organization SAVE LIVES: Clean Your Hands Campaign targets sepsis in health care.
    Intensive Care Med. 2018 Mar 2. pii: 10.1007/s00134-018-5097.
    PubMed    


  98. WEISS SL, Deutschman CS
    Are septic children really just "septic little adults"?
    Intensive Care Med. 2018;44:392-394.
    PubMed    


  99. DE GROOTH HJ, Postema J, Loer SA, Parienti JJ, et al
    Unexplained mortality differences between septic shock trials: a systematic analysis of population characteristics and control-group mortality rates.
    Intensive Care Med. 2018;44:311-322.
    PubMed     Abstract available


  100. VINCENT JL, Lefrant JY, Kotfis K, Nanchal R, et al
    Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP).
    Intensive Care Med. 2018;44:337-344.
    PubMed     Abstract available


  101. WINISZEWSKI H, Labro G, Navellou JC, Piton G, et al
    Septic shock with round necrotic skin lesions.
    Intensive Care Med. 2018;44:374-375.
    PubMed    


    February 2018
  102. VIEILLARD-BARON A, Evrard B, Repesse X, Maizel J, et al
    Limited value of end-expiratory inferior vena cava diameter to predict fluid responsiveness impact of intra-abdominal pressure.
    Intensive Care Med. 2018;44:197-203.
    PubMed     Abstract available


  103. AU SY, Fong KM, Chan KLL, Sin KC, et al
    Diagnosing catheter associated blood-stream infection by transesophageal echocardiogram.
    Intensive Care Med. 2018;44:251.
    PubMed    


    January 2018
  104. SHANKAR-HARI M, Madsen MB, Turgeon AF
    Immunoglobulins and sepsis.
    Intensive Care Med. 2018 Jan 18. pii: 10.1007/s00134-018-5047.
    PubMed    


  105. FUJII T, Ganeko R, Kataoka Y, Furukawa TA, et al
    Correction to: Polymyxin B-immobilized hemoperfusion and mortality in critically ill adult patients with sepsis/septic shock: a systematic review with meta-analysis and trial sequential analysis.
    Intensive Care Med. 2018 Jan 16. pii: 10.1007/s00134-018-5055.
    PubMed     Abstract available


  106. LAMONTAGNE F, Day AG, Meade MO, Cook DJ, et al
    Pooled analysis of higher versus lower blood pressure targets for vasopressor therapy septic and vasodilatory shock.
    Intensive Care Med. 2018;44:12-21.
    PubMed     Abstract available


  107. VAN DER KOOI T, Sax H, Pittet D, van Dissel J, et al
    Prevention of hospital infections by intervention and training (PROHIBIT): results of a pan-European cluster-randomized multicentre study to reduce central venous catheter-related bloodstream infections.
    Intensive Care Med. 2018;44:48-60.
    PubMed     Abstract available


  108. DEPRET F, Sitbon A, Soussi S, De Tymowski C, et al
    Intravenous iloprost to recruit the microcirculation in septic shock patients?
    Intensive Care Med. 2018;44:121-122.
    PubMed    


    December 2017
  109. SCHLAPBACH LJ, Straney L, Bellomo R, MacLaren G, et al
    Prognostic accuracy of age-adapted SOFA, SIRS, PELOD-2, and qSOFA for in-hospital mortality among children with suspected infection admitted to the intensive care unit.
    Intensive Care Med. 2017 Dec 19. pii: 10.1007/s00134-017-5021.
    PubMed     Abstract available


  110. FUJII T, Ganeko R, Kataoka Y, Furukawa TA, et al
    Polymyxin B-immobilized hemoperfusion and mortality in critically ill adult patients with sepsis/septic shock: a systematic review with meta-analysis and trial sequential analysis.
    Intensive Care Med. 2017 Dec 4. pii: 10.1007/s00134-017-5004.
    PubMed     Abstract available


  111. MARX G
    Correction to: Incidence of severe sepsis and septic shock in German intensive care units: the prospective, multicentre INSEP study.
    Intensive Care Med. 2017 Dec 1. pii: 10.1007/s00134-017-4980.
    PubMed     Abstract available


    November 2017
  112. VIEILLARD-BARON A, Boyd J
    Non-antiarrhythmic interventions in new onset and paroxysmal sepsis-related atrial fibrillation.
    Intensive Care Med. 2017 Nov 7. doi: 10.1007/s00134-017-4986.
    PubMed    


    October 2017
  113. NUNES C, Carvalho R, Ribeiro L, Lencastre L, et al
    When acrocyanosis in intensive care unit is not due to vasopressor support.
    Intensive Care Med. 2017 Oct 7. doi: 10.1007/s00134-017-4952.
    PubMed    


    September 2017
  114. ANNANE D, Pastores SM, Rochwerg B, Arlt W, et al
    Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017.
    Intensive Care Med. 2017 Sep 21. doi: 10.1007/s00134-017-4919.
    PubMed     Abstract available


    August 2017
  115. TEBOUL JL, Duranteau J, Russell JA
    Intensive care medicine in 2050: vasopressors in sepsis.
    Intensive Care Med. 2017 Aug 31. doi: 10.1007/s00134-017-4909.
    PubMed    


  116. BAHLOUL M, Chtara K, Turki O, Khlaf Bouaziz N, et al
    Yarrowia lipolytica fungemia in patients with severe polytrauma requiring intensive care admission: analysis of 32 cases.
    Intensive Care Med. 2017 Aug 5. doi: 10.1007/s00134-017-4900.
    PubMed    


    July 2017
  117. AZOULAY E, Schellongowski P, Darmon M, Bauer PR, et al
    The Intensive Care Medicine research agenda on critically ill oncology and hematology patients.
    Intensive Care Med. 2017 Jul 19. doi: 10.1007/s00134-017-4884.
    PubMed     Abstract available


  118. GAUDRY S, Hajage D, Dreyfuss D, Joannidis M, et al
    Optimal timing of renal replacement therapy in patients with acute kidney injury in the context of sepsis : Discussion on "Sepsis: frontiers in supportive care, organisation and research".
    Intensive Care Med. 2017 Jul 12. doi: 10.1007/s00134-017-4856.
    PubMed    


    June 2017
  119. YAMAGA S, Shime N, Sonneville R, de Montmollin E, et al
    Risk factors for sepsis-associated encephalopathy.
    Intensive Care Med. 2017 Jun 29. doi: 10.1007/s00134-017-4875.
    PubMed    


  120. MER M, Schultz MJ, Adhikari NK
    Core elements of general supportive care for patients with sepsis and septic shock in resource-limited settings.
    Intensive Care Med. 2017 Jun 15. doi: 10.1007/s00134-017-4831.
    PubMed    


  121. YAMAGUCHI RS, Noritomi DT, Degaspare NV, Munoz GOC, et al
    Peripherally inserted central catheters are associated with lower risk of bloodstream infection compared with central venous catheters in paediatric intensive care patients: a propensity-adjusted analysis.
    Intensive Care Med. 2017 Jun 5. doi: 10.1007/s00134-017-4852.
    PubMed     Abstract available


    May 2017
  122. PERNER A, Gordon AC, Angus DC, Lamontagne F, et al
    The intensive care medicine research agenda on septic shock.
    Intensive Care Med. 2017 May 12. doi: 10.1007/s00134-017-4821.
    PubMed     Abstract available


  123. BLOOS F, Ruddel H, Thomas-Ruddel D, Schwarzkopf D, et al
    Effect of a multifaceted educational intervention for anti-infectious measures on sepsis mortality: a cluster randomized trial.
    Intensive Care Med. 2017 May 2. doi: 10.1007/s00134-017-4782.
    PubMed     Abstract available


  124. SONNEVILLE R, de Montmollin E, Poujade J, Garrouste-Orgeas M, et al
    Potentially modifiable factors contributing to sepsis-associated encephalopathy.
    Intensive Care Med. 2017 May 2. doi: 10.1007/s00134-017-4807.
    PubMed     Abstract available


  125. LORTHOLARY O, Renaudat C, Sitbon K, Desnos-Ollivier M, et al
    The risk and clinical outcome of candidemia depending on underlying malignancy.
    Intensive Care Med. 2017;43:652-662.
    PubMed     Abstract available


  126. BOISSIER F, Razazi K, Seemann A, Bedet A, et al
    Left ventricular systolic dysfunction during septic shock: the role of loading conditions.
    Intensive Care Med. 2017;43:633-642.
    PubMed     Abstract available


    April 2017
  127. SCHLAPBACH LJ, Javouhey E, Jansen NJG
    Paediatric sepsis: old wine in new bottles?
    Intensive Care Med. 2017 Apr 22. doi: 10.1007/s00134-017-4800.
    PubMed    


  128. MARTIN-LOECHES I, Garnacho-Montero J, Nseir S
    Focus on infection and sepsis 2017.
    Intensive Care Med. 2017 Apr 4. doi: 10.1007/s00134-017-4787.
    PubMed    


  129. BASSETTI M, Peghin M, Carnelutti A, Righi E, et al
    Clinical characteristics and predictors of mortality in cirrhotic patients with candidemia and intra-abdominal candidiasis: a multicenter study.
    Intensive Care Med. 2017;43:509-518.
    PubMed     Abstract available


    March 2017
  130. BELLOMO R, Kellum JA, Ronco C, Wald R, et al
    Acute kidney injury in sepsis.
    Intensive Care Med. 2017 Mar 31. doi: 10.1007/s00134-017-4755.
    PubMed     Abstract available


  131. FORWARD E, Konecny P, Burston J, Adhikari S, et al
    Predictive validity of the qSOFA criteria for sepsis in non-ICU inpatients.
    Intensive Care Med. 2017 Mar 29. doi: 10.1007/s00134-017-4776.
    PubMed    


  132. SCHULTZ MJ, Dunser MW, Dondorp AM, Adhikari NK, et al
    Current challenges in the management of sepsis in ICUs in resource-poor settings and suggestions for the future.
    Intensive Care Med. 2017 Mar 27. doi: 10.1007/s00134-017-4750.
    PubMed     Abstract available


  133. GENGA KR, Russell JA
    How much excess fluid impairs outcome of sepsis?
    Intensive Care Med. 2017 Mar 27. doi: 10.1007/s00134-017-4746.
    PubMed    


  134. SCULLY T, Clancy D, McLean AS, Orde S, et al
    Reversal in order of ventricular filling is associated with a positive fluid balance in sepsis.
    Intensive Care Med. 2017 Mar 23. doi: 10.1007/s00134-017-4769.
    PubMed    


  135. PICKKERS P, Payen D
    What's new in the extracorporeal treatment of sepsis?
    Intensive Care Med. 2017 Mar 17. doi: 10.1007/s00134-017-4738.
    PubMed    


  136. BASSETTI M, Garnacho-Montero J, Calandra T, Kullberg B, et al
    Intensive care medicine research agenda on invasive fungal infection in critically ill patients.
    Intensive Care Med. 2017 Mar 2. doi: 10.1007/s00134-017-4731.
    PubMed     Abstract available


    February 2017
  137. WONG HR
    Intensive care medicine in 2050: precision medicine.
    Intensive Care Med. 2017 Feb 24. doi: 10.1007/s00134-017-4727.
    PubMed    


  138. ESTEBAN E, Belda S, Garcia-Soler P, Rodriguez-Nunez A, et al
    A multifaceted educational intervention shortened time to antibiotic administration in children with severe sepsis and septic shock: ABISS Edusepsis pediatric study.
    Intensive Care Med. 2017 Feb 20. doi: 10.1007/s00134-017-4721.
    PubMed    


  139. SCHLAPBACH LJ, MacLaren G, Festa M, Alexander J, et al
    Prediction of pediatric sepsis mortality within 1 h of intensive care admission.
    Intensive Care Med. 2017 Feb 20. doi: 10.1007/s00134-017-4701.
    PubMed     Abstract available


  140. LEVI M, Schultz MJ
    What do sepsis-induced coagulation test result abnormalities mean to intensivists?
    Intensive Care Med. 2017 Feb 20. doi: 10.1007/s00134-017-4725.
    PubMed    


  141. MEZIANI F, Gando S, Vincent JL
    Should all patients with sepsis receive anticoagulation? Yes.
    Intensive Care Med. 2017 Feb 13. doi: 10.1007/s00134-016-4621.
    PubMed    


  142. ZHANG Z, Hong Y, Liu N, Chen Y, et al
    Association of do-not-resuscitate order and survival in patients with severe sepsis and/or septic shock.
    Intensive Care Med. 2017 Feb 2. doi: 10.1007/s00134-017-4690.
    PubMed    


  143. KERHUEL L, Valade S, Donay JL, Canet E, et al
    Angina, back pain and septic shock.
    Intensive Care Med. 2017;43:269-270.
    PubMed    


    January 2017
  144. MARLAIS M, Lyttle MD, Inwald D
    Erratum to: Ten concerns about blood pressure measurement and targets in paediatric sepsis.
    Intensive Care Med. 2017 Jan 31. doi: 10.1007/s00134-017-4692.
    PubMed    


  145. MARIK PE, Linde-Zwirble WT, Bittner EA, Sahatjian J, et al
    Fluid administration in severe sepsis and septic shock, patterns and outcomes: an analysis of a large national database.
    Intensive Care Med. 2017 Jan 27. doi: 10.1007/s00134-016-4675.
    PubMed     Abstract available


  146. PERNER A, Rhodes A, Venkatesh B, Angus DC, et al
    Sepsis: frontiers in supportive care, organisation and research.
    Intensive Care Med. 2017 Jan 27. doi: 10.1007/s00134-017-4677.
    PubMed     Abstract available


  147. RHODES A, Evans LE, Alhazzani W, Levy MM, et al
    Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.
    Intensive Care Med. 2017 Jan 18. doi: 10.1007/s00134-017-4683.
    PubMed     Abstract available


  148. DELLINGER RP, Schorr CA, Levy MM
    A users' guide to the 2016 Surviving Sepsis Guidelines.
    Intensive Care Med. 2017 Jan 18. doi: 10.1007/s00134-017-4681.
    PubMed    


  149. LANKELMA JM, van Vught LA, Belzer C, Schultz MJ, et al
    Critically ill patients demonstrate large interpersonal variation in intestinal microbiota dysregulation: a pilot study.
    Intensive Care Med. 2017;43:59-68.
    PubMed     Abstract available


    December 2016
  150. AUBRY A, Allouch P, Squara P, Vieillard-Baron A, et al
    A "UFO" in the right pulmonary artery after cardiac surgery.
    Intensive Care Med. 2016 Dec 24. doi: 10.1007/s00134-016-4644.
    PubMed    


  151. MARLAIS M, Lyttle MD, Inwald D
    Ten concerns about blood pressure measurement and targets in paediatric sepsis.
    Intensive Care Med. 2016.
    PubMed    


    November 2016
  152. IBA T, Thachil J
    Is protein C zymogen really ineffective for ALL cases of sepsis including septic DIC?
    Intensive Care Med. 2016.
    PubMed    


  153. SPRUNG CL, Schein RM, Balk RA
    The new sepsis consensus definitions: the good, the bad and the ugly.
    Intensive Care Med. 2016.
    PubMed    


  154. SINGER M
    The new sepsis consensus definitions (Sepsis-3): the good, the not-so-bad, and the actually-quite-pretty.
    Intensive Care Med. 2016.
    PubMed    


    October 2016
  155. TIMSIT JF, Perner A
    Sepsis: find me, manage me, and stop me!
    Intensive Care Med. 2016.
    PubMed    


  156. KRUGER PS, Terblanche M
    Statins in patients with sepsis and ARDS: is it over? No.
    Intensive Care Med. 2016.
    PubMed    


  157. MCAULEY D, Charles PE, Papazian L
    Statins in patients with sepsis and ARDS: is it over? We are not sure.
    Intensive Care Med. 2016.
    PubMed    


  158. ALHAZZANI W, Truwit J
    Statins in patients with sepsis and ARDS: is it over? Yes.
    Intensive Care Med. 2016.
    PubMed    


  159. THWAITES CL, Lundeg G, Dondorp AM
    Infection management in patients with sepsis and septic shock in resource-limited settings.
    Intensive Care Med. 2016.
    PubMed    


  160. ROSHDY A
    Infection management in patients with sepsis and septic shock in resource-limited settings: focus on appropriate antimicrobial.
    Intensive Care Med. 2016.
    PubMed    


  161. SILVERSIDES JA, Major E, Ferguson AJ, Mann EE, et al
    Conservative fluid management or deresuscitation for patients with sepsis or acute respiratory distress syndrome following the resuscitation phase of critical illness: a systematic review and meta-analysis.
    Intensive Care Med. 2016.
    PubMed     Abstract available


  162. MORIN L, Ray S, Wilson C, Remy S, et al
    Refractory septic shock in children: a European Society of Paediatric and Neonatal Intensive Care definition.
    Intensive Care Med. 2016.
    PubMed     Abstract available


  163. VINCENT JL, Martin-Loeches I, Annane D
    What patient data should be collected in this randomized controlled trial in sepsis?
    Intensive Care Med. 2016.
    PubMed    


  164. PERNER A, Gordon AC, De Backer D, Dimopoulos G, et al
    Sepsis: frontiers in diagnosis, resuscitation and antibiotic therapy.
    Intensive Care Med. 2016.
    PubMed     Abstract available


    September 2016
  165. DELANEY A, Machado F
    In sepsis, everything old is new again.
    Intensive Care Med. 2016.
    PubMed    



  166. Incidence of severe sepsis and septic shock in German intensive care units: the prospective, multicentre INSEP study.
    Intensive Care Med. 2016.
    PubMed     Abstract available


  167. JENSEN JU, Bouadma L
    Why biomarkers failed in sepsis.
    Intensive Care Med. 2016.
    PubMed    


  168. BLOCH A, Berger D, Takala J
    Understanding circulatory failure in sepsis.
    Intensive Care Med. 2016.
    PubMed    


    April 2016
  169. ALLINGSTRUP M, Wetterslev J, Ravn FB, Moller AM, et al
    Antithrombin III for critically ill patients: a systematic review with meta-analysis and trial sequential analysis.
    Intensive Care Med. 2016;42:505-20.
    PubMed     Abstract available


  170. BAILLY S, Pirracchio R, Timsit JF
    What's new in the quantification of causal effects from longitudinal cohort studies: a brief introduction to marginal structural models for intensivists.
    Intensive Care Med. 2016;42:576-9.
    PubMed    


    March 2016
  171. DE MOURA EB, Amorim FF, da Cruz Santana AN, Kanhouche G, et al
    Skin mottling score as a predictor of 28-day mortality in patients with septic shock.
    Intensive Care Med. 2016;42:479-80.
    PubMed    


  172. DEPUYDT PO, Kress JP, Salluh JI
    The ten "diseases" that are not true diseases.
    Intensive Care Med. 2016;42:411-4.
    PubMed    


    February 2016
  173. CLARK E, Kumar A, Langote A, Lapinsky S, et al
    Septic shock in chronic dialysis patients: clinical characteristics, antimicrobial therapy and mortality.
    Intensive Care Med. 2016;42:222-32.
    PubMed     Abstract available


  174. FALCONE M, Russo A, Farcomeni A, Pieralli F, et al
    Septic shock from community-onset pneumonia: is there a role for aspirin plus macrolides combination?
    Intensive Care Med. 2016;42:301-2.
    PubMed    


  175. OSPINA-TASCON GA, Umana M, Bermudez WF, Bautista-Rincon DF, et al
    Can venous-to-arterial carbon dioxide differences reflect microcirculatory alterations in patients with septic shock?
    Intensive Care Med. 2016;42:211-21.
    PubMed     Abstract available


  176. HAAS SA, Lange T, Saugel B, Petzoldt M, et al
    Severe hyperlactatemia, lactate clearance and mortality in unselected critically ill patients.
    Intensive Care Med. 2016;42:202-10.
    PubMed     Abstract available


    January 2016
  177. HSU CW, Lin CS, Chen SJ, Lin SH, et al
    Risk of type 2 diabetes mellitus in patients with acute critical illness: a population-based cohort study.
    Intensive Care Med. 2016;42:38-45.
    PubMed     Abstract available


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