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Articles published in Cancer Res

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Single Articles


    June 2018
  1. WANG L, Felts SJ, Van Keulen VP, Scheid AD, et al
    Integrative genome-wide analysis of long noncoding RNAs in diverse immune cell types of melanoma patients.
    Cancer Res. 2018 Jun 12. pii: 0008-5472.CAN-18-0529.
    PubMed     Text format     Abstract available


    May 2018
  2. HUERGO ZAPICO L, Parodi M, Cantoni C, Lavarello C, et al
    NK cell editing mediates Epithelial to Mesenchymal Transition via phenotypic and proteomic changes in melanoma cell lines.
    Cancer Res. 2018 May 11. pii: 0008-5472.CAN-17-1891.
    PubMed     Text format     Abstract available


    February 2018
  3. HOULES T, Gravel SP, Lavoie G, Shin S, et al
    RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma.
    Cancer Res. 2018 Feb 12. pii: 0008-5472.CAN-17-2215.
    PubMed     Text format     Abstract available


    January 2018
  4. UNBEKANDT M, Belshaw S, Bower J, Clarke M, et al
    Discovery of potent and selective MRCK inhibitors with therapeutic effect on skin cancer.
    Cancer Res. 2018 Jan 30. pii: 0008-5472.CAN-17-2870.
    PubMed     Text format     Abstract available


    December 2017
  5. SHARMA C, Wang HX, Li Q, Knoblich K, et al
    Protein Acyltransferase DHHC3 Regulates Breast Tumor Growth, Oxidative Stress, and Senescence.
    Cancer Res. 2017;77:6880-6890.
    PubMed     Text format     Abstract available


  6. DIAZ-MARTINEZ M, Benito-Jardon L, Alonso L, Koetz-Ploch L, et al
    miR-204-5p and miR-211-5p contribute to BRAF inhibitor resistance in melanoma.
    Cancer Res. 2017 Dec 11. pii: 0008-5472.CAN-17-1318.
    PubMed     Text format     Abstract available


    November 2017
  7. EMERSON MA, Banegas MP, Chawla N, Achacoso N, et al
    Disparities in Prostate, Lung, Breast, and Colorectal Cancer Survival and Comorbidity Status among Urban American Indians and Alaskan Natives.
    Cancer Res. 2017 Nov 29. pii: 0008-5472.CAN-17-0429.
    PubMed     Text format     Abstract available


  8. WANG G, Mustafi S, Camarena V, Volmar CH, et al
    Vitamin C sensitizes melanoma to BET inhibitors.
    Cancer Res. 2017 Nov 27. pii: 0008-5472.CAN-17-2040.
    PubMed     Text format     Abstract available


  9. BRIGHTON HE, Angus SP, Bo T, Roques J, et al
    New mechanisms of resistance to MEK inhibitors in melanoma revealed by intravital imaging.
    Cancer Res. 2017 Nov 27. pii: 0008-5472.CAN-17-1653.
    PubMed     Text format     Abstract available


  10. MO X, Zhang H, Preston S, Martin K, et al
    Interferon-2; signaling in melanocytes and melanoma cells regulates expression of CTLA-4.
    Cancer Res. 2017 Nov 17. pii: canres.1615.2017.
    PubMed     Text format     Abstract available


  11. PALMER JR, Castro-Webb N, Bertrand K, Bethea TN, et al
    Type II Diabetes and Incidence of Estrogen Receptor Negative Breast Cancer in African American Women.
    Cancer Res. 2017;77:6462-6469.
    PubMed     Text format     Abstract available


  12. HUANG WY, Lai SF, Chiu HY, Chang M, et al
    Mobilizing Transit-Amplifying Cell-Derived Ectopic Progenitors Prevents Hair Loss from Chemotherapy or Radiation Therapy.
    Cancer Res. 2017;77:6083-6096.
    PubMed     Text format     Abstract available


  13. VENTURA J, Lobachevsky PN, Palazzolo JS, Forrester H, et al
    Localized Synchrotron Irradiation of Mouse Skin Induces Persistent Systemic Genotoxic and Immune Responses.
    Cancer Res. 2017 Nov 7. doi: 10.1158/0008-5472.CAN-17-1066.
    PubMed     Text format     Abstract available


  14. HUA KT, Hong JB, Sheen YS, Huang HY, et al
    MicroRNA-519d promotes melanoma progression by downregulating EphA4.
    Cancer Res. 2017 Nov 1. pii: canres.1933.2017.
    PubMed     Text format     Abstract available


    October 2017
  15. BLATTNER C, Fleming V, Weber R, Himmelhan BS, et al
    CCR5+ myeloid-derived suppressor cells are enriched and activated in melanoma lesions.
    Cancer Res. 2017 Oct 31. pii: canres.0348.2017.
    PubMed     Text format     Abstract available


  16. LI Y, Zhong C, Liu D, Yu W, et al
    Evidence for Kaposi's Sarcoma originating from Mesenchymal Stem Cell through KSHV-induced Mesenchymal-to-Endothelial Transition.
    Cancer Res. 2017 Oct 24. pii: canres.1961.2017.
    PubMed     Text format     Abstract available


  17. TURCOTTE M, Allard D, Mittal D, Bareche Y, et al
    CD73 Promotes Resistance to HER2/ErbB2 Antibody Therapy.
    Cancer Res. 2017;77:5652-5663.
    PubMed     Text format     Abstract available


  18. COUNTER CM, Crowe MS, Greenberg DN, Brady DC, et al
    Copper Chelation Inhibits BRAFV600E-driven Melanomagenesis and Counters Resistance to BRAFV600E and MEK1/2 Inhibitors.
    Cancer Res. 2017 Oct 6. pii: canres.1190.2016.
    PubMed     Text format     Abstract available


  19. CHANG CH, Wang Y, Li R, Rossi DL, et al
    Combination Therapy with Bispecific Antibodies and PD-1 Blockade Enhances the Antitumor Potency of T Cells.
    Cancer Res. 2017;77:5384-5394.
    PubMed     Text format     Abstract available


  20. GALL VA, Philips AV, Qiao N, Clise-Dwyer K, et al
    Trastuzumab Increases HER2 Uptake and Cross-Presentation by Dendritic Cells.
    Cancer Res. 2017;77:5374-5383.
    PubMed     Text format     Abstract available


  21. CANEL M, Byron A, Sims AH, Cartier J, et al
    Nuclear FAK and Runx1 Cooperate to Regulate IGFBP3, Cell-Cycle Progression, and Tumor Growth.
    Cancer Res. 2017;77:5301-5312.
    PubMed     Text format     Abstract available


    September 2017
  22. LI J, Yan S, Liu Z, Zhou Y, et al
    Multiregional sequencing reveals genomic alterations and clonal dynamics in primary malignant melanoma of the esophagus.
    Cancer Res. 2017 Sep 29. pii: canres.0938.2017.
    PubMed     Text format     Abstract available


  23. ISHIHARA S, Inman DR, Li WJ, Ponik SM, et al
    Mechano-signal transduction in mesenchymal stem cells induces prosaposin secretion to drive the proliferation of breast cancer cells.
    Cancer Res. 2017 Sep 28. pii: canres.0569.2017.
    PubMed     Text format     Abstract available


  24. YANG A, Qin S, Schulte BA, Ethier SP, et al
    MYC Inhibition depletes cancer stem-like cells in triple-negative breast cancer.
    Cancer Res. 2017 Sep 26. pii: canres.3452.2016.
    PubMed     Text format     Abstract available


  25. WANG JY, Liu GZ, Wilmott JS, La T, et al
    Skp2-mediated stabilization of MTH1 promotes survival of melanoma cells upon oxidative stress.
    Cancer Res. 2017 Sep 25. pii: canres.1965.2017.
    PubMed     Text format     Abstract available


  26. NEISWENDER JV, Kortum RL, Bourque C, Kasheta M, et al
    KIT suppresses BRAFV600E-mutant melanoma by attenuating oncogenic RAS/MAPK signaling.
    Cancer Res. 2017 Sep 25. pii: canres.0473.2017.
    PubMed     Text format     Abstract available


  27. TEO ZL, Versaci S, Dushyanthen S, Caramia F, et al
    Combined CDK4/6 and PI3Kalpha inhibition is synergistic and immunogenic in triple negative breast cancer.
    Cancer Res. 2017 Sep 25. pii: canres.2210.2017.
    PubMed     Text format     Abstract available


  28. CHEN L, Chubak J, Boudreau DM, Barlow WE, et al
    Diabetes treatments and risks of adverse breast cancer outcomes among early stage breast cancer patients: A SEER-Medicare analysis.
    Cancer Res. 2017 Sep 21. pii: canres.0687.2017.
    PubMed     Text format     Abstract available


  29. DAVIES H, Morganella S, Purdie CA, Jang SJ, et al
    Whole-Genome Sequencing Reveals Breast Cancers with Mismatch Repair Deficiency.
    Cancer Res. 2017;77:4755-4762.
    PubMed     Text format     Abstract available


  30. TAKADA M, Zhang W, Suzuki A, Kuroda TS, et al
    FBW7 Loss Promotes Chromosomal Instability and Tumorigenesis via Cyclin E1/CDK2-Mediated Phosphorylation of CENP-A.
    Cancer Res. 2017;77:4881-4893.
    PubMed     Text format     Abstract available


  31. SI Y, Ji X, Cao X, Dai X, et al
    Src Inhibits the Hippo Tumor Suppressor Pathway through Tyrosine Phosphorylation of Lats1.
    Cancer Res. 2017;77:4868-4880.
    PubMed     Text format     Abstract available


  32. TOLOCZKO A, Guo F, Yuen HF, Wen Q, et al
    Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS Kinase and Core Components of the Hippo Pathway.
    Cancer Res. 2017;77:4921-4933.
    PubMed     Text format     Abstract available


  33. SAMPSON J, O'Regan L, Dyer MJS, Bayliss R, et al
    Hsp72 and Nek6 Cooperate to Cluster Amplified Centrosomes in Cancer Cells.
    Cancer Res. 2017;77:4785-4796.
    PubMed     Text format     Abstract available


  34. SONG KH, Choi CH, Lee HJ, Oh SJ, et al
    HDAC1 Upregulation by NANOG Promotes Multidrug Resistance and a Stem-like Phenotype in Immune Edited Tumor Cells.
    Cancer Res. 2017;77:5039-5053.
    PubMed     Text format     Abstract available


  35. MCFARLAND CD, Yaglom JA, Wojtkowiak JW, Scott JG, et al
    The Damaging Effect of Passenger Mutations on Cancer Progression.
    Cancer Res. 2017;77:4763-4772.
    PubMed     Text format     Abstract available


  36. KATZENELLENBOGEN BS, Zhao Y, Laws MJ, Sanabria Guillen V, et al
    Structurally novel antiestrogens elicit differential responses from constitutively active mutant estrogen receptors in breast cancer cells and tumors.
    Cancer Res. 2017 Sep 13. pii: canres.1265.2017.
    PubMed     Text format     Abstract available


  37. NDOYE A, Budina-Kolomets A, Kugel CH, Webster MR, et al
    ATG5 mediates a positive feedback loop between Wnt signaling and autophagy in melanoma.
    Cancer Res. 2017 Sep 8. pii: canres.0907.2017.
    PubMed     Text format     Abstract available


  38. DETHLEFSEN C, Hansen LS, Lillelund C, Andersen C, et al
    Exercise-Induced Catecholamines Activate the Hippo Tumor Suppressor Pathway to Reduce Risks of Breast Cancer Development.
    Cancer Res. 2017 Sep 8. doi: 10.1158/0008-5472.CAN-16-3125.
    PubMed     Text format     Abstract available


  39. METZGER E, Stepputtis SS, Strietz J, Preca BT, et al
    KDM4 inhibition targets breast cancer stem-like cells.
    Cancer Res. 2017 Sep 7. pii: canres.1754.2017.
    PubMed     Text format     Abstract available


  40. RIOS-LUCI C, Garcia-Alonso S, Diaz-Rodriguez E, Nadal-Serrano M, et al
    Resistance to the Antibody-Drug Conjugate T-DM1 Is Based in a Reduction in Lysosomal Proteolytic Activity.
    Cancer Res. 2017;77:4639-4651.
    PubMed     Text format     Abstract available


    August 2017
  41. YANG F, Wei J, Zhang S, Zhang X, et al
    Shrimp miR-S8 suppresses the stemness of human melanoma stem-like cells by targeting the transcription factor YB-1.
    Cancer Res. 2017 Aug 30. pii: canres.1375.2017.
    PubMed     Text format     Abstract available


  42. ROSS MH, Esser AK, Fox GC, Schmieder AH, et al
    Bone-induced expression of integrin beta3 enables targeted nanotherapy of breast cancer metastases.
    Cancer Res. 2017 Aug 30. pii: canres.1225.2017.
    PubMed     Text format     Abstract available


  43. LI J, Gao Z, Zhao D, Zhang L, et al
    PI-273, a substrate-competitive, specific small molecule inhibitor of PI4KIIalpha, inhibits the growth of breast cancer cells.
    Cancer Res. 2017 Aug 21. pii: canres.0484.2017.
    PubMed     Text format     Abstract available


  44. WANG YW, Reder NP, Kang S, Glaser AK, et al
    Raman-Encoded Molecular Imaging with Topically Applied SERS Nanoparticles for Intraoperative Guidance of Lumpectomy.
    Cancer Res. 2017;77:4506-4516.
    PubMed     Text format     Abstract available


  45. JDEY W, Thierry S, Popova T, Stern MH, et al
    Micronuclei Frequency in Tumors Is a Predictive Biomarker for Genetic Instability and Sensitivity to the DNA Repair Inhibitor AsiDNA.
    Cancer Res. 2017;77:4207-4216.
    PubMed     Text format     Abstract available


  46. SAHNI JM, Gayle SS, Webb B, Weber-Bonk KL, et al
    Mitotic vulnerability in triple-negative breast cancer associated with LIN9 is targetable with BET inhibitors.
    Cancer Res. 2017 Aug 14. pii: canres.1571.2017.
    PubMed     Text format     Abstract available


  47. CHAN CHT, Munusamy P, Loke SY, Koh GL, et al
    Identification of Novel Breast Cancer Risk Loci.
    Cancer Res. 2017 Aug 3. pii: canres.0992.2017.
    PubMed     Text format     Abstract available


  48. ZAMOISKI RD, Yanik E, Gibson TM, Cahoon EK, et al
    Risk of Second Malignancies in Solid Organ Transplant Recipients Who Develop Keratinocyte Cancers.
    Cancer Res. 2017;77:4196-4203.
    PubMed     Text format     Abstract available


  49. ZOU X, Zhu Y, Park SH, Liu G, et al
    SIRT3-Mediated Dimerization of IDH2 Directs Cancer Cell Metabolism and Tumor Growth.
    Cancer Res. 2017;77:3990-3999.
    PubMed     Text format     Abstract available


  50. DONGRE A, Rashidian M, Reinhardt F, Bagnato A, et al
    Epithelial-to-Mesenchymal Transition Contributes to Immunosuppression in Breast Carcinomas.
    Cancer Res. 2017;77:3982-3989.
    PubMed     Text format     Abstract available


    July 2017
  51. REGGIANI F, Labanca V, Mancuso P, Rabascio C, et al
    Adipose progenitor cell secretion of GM-CSF and MMP9 promotes a stromal and immunological microenvironment that supports breast cancer progression.
    Cancer Res. 2017 Jul 28. pii: canres.0914.2017.
    PubMed     Text format     Abstract available


  52. FINLAY-SCHULTZ J, Gillen AE, Brechbuhl HM, Ivie JJ, et al
    Breast cancer suppression by progesterone receptors is mediated by their modulation of estrogen receptors and RNA polymerase III.
    Cancer Res. 2017 Jul 20. pii: canres.3541.2016.
    PubMed     Text format     Abstract available


  53. SALVADOR F, Martin A, Lopez-Menendez C, Moreno-Bueno G, et al
    Lysyl oxidase-like protein LOXL2 promotes lung metastasis of breast cancer.
    Cancer Res. 2017 Jul 18. pii: canres.3152.2016.
    PubMed     Text format     Abstract available


  54. JERMYN M, Mercier J, Aubertin K, Desroches J, et al
    Highly Accurate Detection of Cancer In Situ with Intraoperative, Label-Free, Multimodal Optical Spectroscopy.
    Cancer Res. 2017;77:3942-3950.
    PubMed     Text format     Abstract available


  55. LIU S, Cheng C
    Akt Signaling Is Sustained by a CD44 Splice Isoform-Mediated Positive Feedback Loop.
    Cancer Res. 2017;77:3791-3801.
    PubMed     Text format     Abstract available


  56. SOSSEY-ALAOUI K, Pluskota E, Bialkowska K, Szpak D, et al
    Kindlin-2 regulates the growth of breast cancer tumors by activating CSF-1-mediated macrophage infiltration.
    Cancer Res. 2017 Jul 7. pii: canres.2337.2016.
    PubMed     Text format     Abstract available



  57. Retraction: Molecular Mechanism of MART-1+/A*0201+ Human Melanoma Resistance to Specific CTL-Killing Despite Functional Tumor-CTL Interaction.
    Cancer Res. 2017;77:3718.
    PubMed     Text format    


  58. CASIMIRO MC, Di Sante G, Di Rocco A, Loro E, et al
    Cyclin D1 Restrains Oncogene-Induced Autophagy by Regulating the AMPK-LKB1 Signaling Axis.
    Cancer Res. 2017;77:3391-3405.
    PubMed     Text format     Abstract available


  59. NIE Y, Chen J, Huang D, Yao Y, et al
    Tumor-Associated Macrophages Promote Malignant Progression of Breast Phyllodes Tumors by Inducing Myofibroblast Differentiation.
    Cancer Res. 2017;77:3605-3618.
    PubMed     Text format     Abstract available


    June 2017
  60. REINHARDT J, Landsberg J, Schmid-Burgk JL, Bibiloni Ramis B, et al
    MAPK signaling and inflammation link melanoma phenotype switching to induction of CD73 during immunotherapy.
    Cancer Res. 2017 Jun 26. pii: canres.0395.2017.
    PubMed     Text format     Abstract available


  61. YOUNG A, Ngiow SF, Madore J, Reinhardt J, et al
    Targeting adenosine in BRAF-mutant melanoma reduces tumor growth and metastasis.
    Cancer Res. 2017 Jun 26. pii: canres.0393.2017.
    PubMed     Text format     Abstract available


  62. YOU E, Huh YH, Kwon A, Kim SH, et al
    SPIN90 depletion and Microtubule Acetylation Mediate Stromal Fibroblast Activation in Breast Cancer Progression.
    Cancer Res. 2017 Jun 26. pii: canres.0657.2017.
    PubMed     Text format     Abstract available


  63. SALEH SM, Bertos NR, Gruosso T, Gigoux M, et al
    Identification of interacting stromal axes in triple-negative breast cancer.
    Cancer Res. 2017 Jun 26. pii: canres.3427.2016.
    PubMed     Text format     Abstract available


  64. VERHAEGEN ME, Mangelberger D, Harms PW, Eberl M, et al
    Merkel Cell Polyomavirus Small T Antigen Initiates Merkel Cell Carcinoma-like Tumor Development in Mice.
    Cancer Res. 2017;77:3151-3157.
    PubMed     Text format     Abstract available


  65. HUMPHRIES B, Wang Z, Li Y, Jhan JR, et al
    ARHGAP18 downregulation by miR-200b suppresses metastasis of triple negative breast cancer by enhancing activation of RhoA.
    Cancer Res. 2017 Jun 15. pii: canres.3141.2016.
    PubMed     Text format     Abstract available


  66. FLOWERS M, Birkey Reffey S, Mertz SA, Hurlbert M, et al
    Obstacles, Opportunities and Priorities for Advancing Metastatic Breast Cancer Research.
    Cancer Res. 2017 Jun 10. doi: 10.1158/0008-5472.CAN-17-0232.
    PubMed     Text format     Abstract available


  67. BAN Y, Mai J, Li X, Mitchell-Flack M, et al
    Targeting Autocrine CCL5-CCR5 Axis Reprograms Immunosuppressive Myeloid Cells and Reinvigorates Antitumor Immunity.
    Cancer Res. 2017;77:2857-2868.
    PubMed     Text format     Abstract available


    May 2017
  68. VALDEZ KE, Elsarraj HS, Hong Y, Grimm SL, et al
    NEMO, a transcriptional target of estrogen and progesterone, is linked to tumor suppressor PML in breast cancer.
    Cancer Res. 2017 May 17. pii: canres.2794.2016.
    PubMed     Text format     Abstract available


  69. BARTON VN, Christenson JL, Gordon MA, Greene LI, et al
    Androgen receptor supports an anchorage-independent, cancer stem cell-like population in triple-negative breast cancer.
    Cancer Res. 2017 May 16. pii: canres.3240.2016.
    PubMed     Text format     Abstract available


  70. HOLM J, Eriksson L, Ploner A, Eriksson M, et al
    Assessment of breast cancer risk factors reveals subtype heterogeneity.
    Cancer Res. 2017 May 16. pii: canres.2574.2016.
    PubMed     Text format     Abstract available



  71. Correction: Tumor-Intrinsic PD-L1 Signals Regulate Cell Growth, Pathogenesis, and Autophagy in Ovarian Cancer and Melanoma.
    Cancer Res. 2017;77:2770.
    PubMed     Text format    


  72. PRAT A, Navarro A, Pare L, Reguart N, et al
    Immune-related gene expression profiling after PD-1 blockade in non-small cell lung carcinoma, head and neck squamous cell carcinoma and melanoma.
    Cancer Res. 2017 May 9. pii: canres.3556.2017.
    PubMed     Text format     Abstract available


  73. ROSSI EL, Dunlap SM, Bowers LW, Khatib SA, et al
    Energy Balance Modulation Impacts Epigenetic Reprogramming, ERalpha and ERbeta Expression, and Mammary Tumor Development in MMTV-neu Transgenic Mice.
    Cancer Res. 2017;77:2500-2511.
    PubMed     Text format     Abstract available


    April 2017
  74. LI B, Ni Chonghaile T, Fan Y, Madden S, et al
    THERAPEUTIC RATIONALE TO TARGET HIGHLY EXPRESSED CDK7 CONFERRING POOR OUTCOMES IN TRIPLE-NEGATIVE BREAST CANCER.
    Cancer Res. 2017 Apr 28. pii: canres.2546.2016.
    PubMed     Text format     Abstract available


  75. SAFONOV A, Jiang T, Bianchini G, Gyorffy B, et al
    Immune gene expression is associated with genomic aberrations in breast cancer.
    Cancer Res. 2017 Apr 20. pii: canres.3478.2016.
    PubMed     Text format     Abstract available


  76. LU K, Alcivar AL, Ma J, Foo TK, et al
    NRF2 induction supporting breast cancer cell survival is enabled by oxidative stress-induced DPP3-KEAP1 interaction.
    Cancer Res. 2017 Apr 17. pii: canres.2204.2016.
    PubMed     Text format     Abstract available


  77. WANG H, Schaefer T, Konantz M, Braun M, et al
    Prominent Oncogenic Roles of EVI1 in Breast Carcinoma.
    Cancer Res. 2017;77:2148-2160.
    PubMed     Text format     Abstract available


  78. SANSONE P, Berishaj M, Rajasekhar VK, Ceccarelli C, et al
    Evolution of Cancer Stem-like Cells in Endocrine-Resistant Metastatic Breast Cancers Is Mediated by Stromal Microvesicles.
    Cancer Res. 2017;77:1927-1941.
    PubMed     Text format     Abstract available


  79. GAGGIANESI M, Turdo A, Chinnici A, Lipari E, et al
    IL-4 primes the dynamics of breast cancer progression via DUSP4 inhibition.
    Cancer Res. 2017 Apr 11. pii: canres.3126.2016.
    PubMed     Text format     Abstract available


  80. HANKER AB, Estrada MV, Bianchini G, Moore PD, et al
    Extracellular matrix/integrin signaling promotes resistance to combined inhibition of HER2 and PI3K in HER2+ breast cancer.
    Cancer Res. 2017 Apr 10. pii: canres.2808.2016.
    PubMed     Text format     Abstract available


  81. GENDELMAN R, Xing H, Mirzoeva OK, Sarde P, et al
    Bayesian Network Inference Modeling Identifies TRIB1 as a Novel Regulator of Cell-Cycle Progression and Survival in Cancer Cells.
    Cancer Res. 2017;77:1575-1585.
    PubMed     Text format     Abstract available


    March 2017
  82. TEMKO DP, Cheng YK, Polyak K, Michor F, et al
    Mathematical modeling links pregnancy-associated changes and breast cancer risk.
    Cancer Res. 2017 Mar 30. pii: canres.2504.2016.
    PubMed     Text format     Abstract available


  83. LIAO L, Song M, Li X, Tang L, et al
    E3 ubiquitin ligase UBR5 drives the growth and metastasis of triple negative breast cancer.
    Cancer Res. 2017 Mar 22. pii: canres.2409.2016.
    PubMed     Text format     Abstract available



  84. Correction: Differential Regulation of the Melanoma Proteome by eIF4A1 and eIF4E.
    Cancer Res. 2017;77:1505.
    PubMed     Text format    


  85. VALENT P, Akin C, Hartmann K, Nilsson G, et al
    Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future.
    Cancer Res. 2017;77:1261-1270.
    PubMed     Text format     Abstract available


  86. CHOY L, Hagenbeek TJ, Solon M, French D, et al
    Constitutive NOTCH3 Signaling Promotes the Growth of Basal Breast Cancers.
    Cancer Res. 2017;77:1439-1452.
    PubMed     Text format     Abstract available


  87. SHIMELIS H, Mesman RL, Von Nicolai C, Ehlen A, et al
    BRCA2 hypomorphic missense variants confer moderate risks of breast cancer.
    Cancer Res. 2017 Mar 10. pii: canres.2568.2016.
    PubMed     Text format     Abstract available


  88. HARRIS HR, Willett WC, Vaidya RL, Michels KB, et al
    An Adolescent and Early Adulthood Dietary Pattern Associated with Inflammation and the Incidence of Breast Cancer.
    Cancer Res. 2017;77:1179-1187.
    PubMed     Text format     Abstract available


  89. IRSHAD S, Flores-Borja F, Lawler K, Monypenny J, et al
    RORgammat+ Innate Lymphoid Cells Promote Lymph Node Metastasis of Breast Cancers.
    Cancer Res. 2017;77:1083-1096.
    PubMed     Text format     Abstract available


  90. ANJANAPPA M, Cardoso AA, Cheng L, Mohamad S, et al
    Individualized breast cancer characterization through single cell analysis of tumor and adjacent-normal cells.
    Cancer Res. 2017 Mar 1. pii: canres.3308.2016.
    PubMed     Text format     Abstract available


    February 2017
  91. RUPRECHT B, Zaal EA, Zecha J, Wu W, et al
    Lapatinib resistance in breast cancer cells is accompanied by phosphorylation-mediated reprogramming of glycolysis.
    Cancer Res. 2017 Feb 16. pii: canres.2976.2016.
    PubMed     Text format     Abstract available


  92. STEINBERG SM, Shabaneh T, Zhang P, Martyanov V, et al
    Myeloid cells that impair immunotherapy are restored in melanomas which acquire resistance to BRAF inhibitors.
    Cancer Res. 2017 Feb 15. pii: canres.1755.2016.
    PubMed     Text format     Abstract available


  93. JACKSON W, Sosnoski DM, Ohanessian SE, Chandler P, et al
    The Role of Megakaryocytes in Breast Cancer Metastasis to Bone.
    Cancer Res. 2017 Feb 15. pii: canres.1084.2016.
    PubMed     Text format     Abstract available


  94. WRAGG JW, Heath VL, Bicknell R
    Sunitinib Treatment Enhances Metastasis of Innately Drug-Resistant Breast Tumors.
    Cancer Res. 2017;77:1008-1020.
    PubMed     Text format     Abstract available


  95. DZINIC SH, Bernardo MM, Li X, Fernandez-Valdivia R, et al
    An Essential Role of Maspin in Embryogenesis and Tumor Suppression.
    Cancer Res. 2017;77:886-896.
    PubMed     Text format     Abstract available


  96. ZHOU R, Pantel AR, Li S, Lieberman BP, et al
    [18F](2S,4R)4-Fluoroglutamine PET Detects Glutamine Pool Size Changes in Triple Negative Breast Cancer in Response to Glutaminase Inhibition.
    Cancer Res. 2017 Feb 15. pii: canres.1945.2016.
    PubMed     Text format     Abstract available


  97. NOLAN E, Lindeman GJ, Visvader JE
    Out-RANKing BRCA1 in Mutation Carriers.
    Cancer Res. 2017;77:595-600.
    PubMed     Text format     Abstract available


  98. HENRY WS, Laszewski T, Tsang T, Beca F, et al
    Aspirin Suppresses Growth in PI3K-Mutant Breast Cancer by Activating AMPK and Inhibiting mTORC1 Signaling.
    Cancer Res. 2017;77:790-801.
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    January 2017
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    Aberrant phosphorylation of SMAD4 Thr277-mediated USP9x-SMAD4 interaction by free fatty acids promotes breast cancer metastasis.
    Cancer Res. 2017 Jan 23. pii: canres.2012.2016.
    PubMed     Text format     Abstract available


  100. ZHANG T, Xu M, Makowski MM, Lee C, et al
    SDHD promoter mutations ablate GABP transcription factor binding in melanoma.
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  101. SUAREZ-CABRERA C, Quintana RM, Bravo A, Casanova ML, et al
    A transposon-based analysis reveals RASA1 is involved in triple negative breast cancer.
    Cancer Res. 2017 Jan 20. pii: canres.1586.2016.
    PubMed     Text format     Abstract available


  102. NEUBERT NJ, Tille L, Barras D, Soneson C, et al
    Broad and conserved immune regulation by genetically heterogeneous melanoma cells.
    Cancer Res. 2017 Jan 19. pii: canres.2680.2016.
    PubMed     Text format     Abstract available


  103. SHI Y, Steppi A, Cao Y, Wang J, et al
    Integrative Comparison of mRNA Expression Patterns in Breast Cancers from Caucasian and Asian Americans with Implications for Precision Medicine.
    Cancer Res. 2017;77:423-433.
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  104. KAZAZIAN K, Go C, Wu H, Brashavitskaya O, et al
    Plk4 Promotes Cancer Invasion and Metastasis through Arp2/3 Complex Regulation of the Actin Cytoskeleton.
    Cancer Res. 2017;77:434-447.
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  105. ROUSSEL-GERVAIS A, Naciri I, Kirsh O, Kasprzyk L, et al
    Loss of the Methyl-CpG-Binding Protein ZBTB4 Alters Mitotic Checkpoint, Increases Aneuploidy, and Promotes Tumorigenesis.
    Cancer Res. 2017;77:62-73.
    PubMed     Text format     Abstract available


  106. VERMA N, Muller AK, Kothari C, Panayotopoulou E, et al
    Targeting of PYK2 Synergizes with EGFR Antagonists in Basal-like TNBC and Circumvents HER3-Associated Resistance via the NEDD4-NDRG1 Axis.
    Cancer Res. 2017;77:86-99.
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  107. JIANG J, Gui F, He Z, Li L, et al
    Targeting BRK-Positive Breast Cancers with Small-Molecule Kinase Inhibitors.
    Cancer Res. 2017;77:175-186.
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    December 2016
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    Association of Estrogen Metabolism with Breast Cancer Risk in Different Cohorts of Postmenopausal Women.
    Cancer Res. 2016 Dec 23. pii: canres.1717.2016.
    PubMed     Text format     Abstract available


    November 2016
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    Differential regulation of the melanoma proteome by eIF4A1 and eIF4E.
    Cancer Res. 2016 Nov 22. pii: canres.1298.2016.
    PubMed     Text format     Abstract available


  110. JAEGER S, Igea A, Arroyo R, Alcalde V, et al
    Quantification of pathway crosstalk reveals novel synergistic drug combinations for breast cancer.
    Cancer Res. 2016 Nov 22. pii: canres.0097.2016.
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  111. SHIBATA T, Watari K, Izumi H, Kawahara A, et al
    Breast cancer resistance to antiestrogens is enhanced by increased ER degradation and ERBB2 expression.
    Cancer Res. 2016 Nov 22. pii: canres.1593.2016.
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  112. KOCH M, de Jong JS, Glatz J, Symvoulidis P, et al
    Threshold analysis and biodistribution of fluorescently labeled bevacizumab in human breast cancer.
    Cancer Res. 2016 Nov 22. pii: canres.1773.2016.
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  113. WALI VB, Langdon CG, Held MA, Platt JT, et al
    Systematic drug screening identifies tractable targeted combination therapies in triple-negative breast cancer.
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  114. DOWER CM, Bhat N, Wang EW, Wang HG, et al
    Selective Reversible Inhibition of Autophagy in Hypoxic Breast Cancer Cells Promotes Pulmonary Metastasis.
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  115. AZAN A, Caspers PJ, Bakker Schut TC, Roy S, et al
    A Novel Spectroscopically Determined Pharmacodynamic Biomarker for Skin Toxicity in Cancer Patients Treated with Targeted Agents.
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  116. M ISMAIL TM, Bennett D, Platt-Higgins AM, Al-Medhtiy M, et al
    S100A4 elevation empowers expression of metastasis effector molecules in human breast cancer.
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    October 2016
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    Human chorionic gonadotropin does not correlate with risk for maternal breast cancer: results from the Finnish maternity cohort.
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  118. FISHER ML, Kerr C, Adhikary G, Grun D, et al
    Transglutaminase interaction with alpha6/beta4-integrin stimulates YAP1-dependent DeltaNp63alpha stabilization and leads to enhanced cancer stem cell survival and tumor formation.
    Cancer Res. 2016 Oct 25. pii: canres.2032.2016.
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  119. METELLI A, Wu BX, Fugle CW, Rachidi S, et al
    Surface Expression of TGFbeta Docking Receptor GARP Promotes Oncogenesis and Immune Tolerance in Breast Cancer.
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  120. CHIANG S, Weigelt B, Wen HC, Pareja F, et al
    IDH2 Mutations Define a Unique Subtype of Breast Cancer with Altered Nuclear Polarity.
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  121. COOK KL, Soto-Pantoja DR, Clarke PA, Cruz MI, et al
    Endoplasmic Reticulum Stress Protein GRP78 Modulates Lipid Metabolism to Control Drug Sensitivity and Antitumor Immunity in Breast Cancer.
    Cancer Res. 2016;76:5657-5670.
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    September 2016
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    Recurrent loss of STING Signaling in Melanoma Correlates with Susceptibility to Viral Oncolysis.
    Cancer Res. 2016 Sep 28. pii: canres.1404.2016.
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  123. KIM M, Neznanov N, Wilfong CD, Fleyshman DI, et al
    Preclinical validation of a single-treatment infusion modality that can eradicate extremity melanomas.
    Cancer Res. 2016 Sep 28. pii: canres.2764.2015.
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  124. SATOW R, Nakamura T, Kato C, Endo M, et al
    ZIC5 drives melanoma aggressiveness by PDGFD-mediated activation of FAK and STAT3.
    Cancer Res. 2016 Sep 26. pii: canres.0991.2016.
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  125. CLARK CA, Gupta H, Sareddy GR, Pandeswara S, et al
    Tumor-intrinsic PD-L1 signals regulate cell growth, pathogenesis and autophagy in ovarian cancer and melanoma.
    Cancer Res. 2016 Sep 26. pii: canres.0258.2016.
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  126. RAO SS, Bushnell GG, Azarin SM, Spicer G, et al
    Enhanced Survival with Implantable Scaffolds That Capture Metastatic Breast Cancer Cells In Vivo.
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  127. KLARQUIST J, Tobin K, Farhangi Oskuei P, Henning SW, et al
    CCL22 DIVERTS T REGULATORY CELLS AND CONTROLS THE GROWTH OF MELANOMA.
    Cancer Res. 2016 Sep 12. pii: canres.0618.2016.
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  128. TAKAHASHI N, Sugaya M, Suga H, Oka T, et al
    Thymic stromal chemokine TSLP acts through Th2 cytokine production to induce cutaneous T cell lymphoma.
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    August 2016
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    Wnt signaling promotes breast cancer by blocking ITCH-mediated degradation of the YAP/TAZ transcriptional coactivator WBP2.
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  130. AIROLDI I, Cocco C, Sorrentino C, Angelucci D, et al
    Interleukin-30 promotes breast cancer growth and progression.
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  131. TEH JL, Purwin TJ, Greenawalt EJ, Chervoneva I, et al
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    June 2016
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    Expansion of a BDCA1<sup>+</sup>CD14<sup>+</sup> myeloid cell population in melanoma patients may attenuate the efficacy of dendritic cell vaccines.
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  134. BOYLE SE, Fedele CG, Corbin V, Wybacz E, et al
    CD271 Expression on Patient Melanoma Cells Is Unstable and Unlinked to Tumorigenicity.
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    Melanoma lesions independently acquire T-cell resistance during metastatic latency.
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    Incipient melanoma brain metastases instigate astrogliosis and neuroinflammation.
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    May 2016
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    Multi-region whole-exome sequencing uncovers the genetic evolution and mutational heterogeneity of early-stage metastatic melanoma.
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  138. LAZAR I, Clement E, Dauvillier S, Milhas D, et al
    Adipocyte exosomes promote melanoma aggressiveness through fatty acid oxidation: a novel mechanism linking obesity and cancer.
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  139. YAMADA K, Uchiyama A, Uehara A, Perera B, et al
    MFG-E8 drives melanoma growth by stimulating mesenchymal stromal cell-induced angiogenesis and M2 polarization of tumor-associated macrophages.
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  140. HOLLANDER L, Guo X, Velazquez H, Chang J, et al
    Renalase expression by melanoma and tumor associated-macrophages promotes tumor growth through a STAT3-mediated mechanism.
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    April 2016
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    Antibody Targeted Chemotherapy for the Treatment of Melanoma.
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    miR-339-3p is a tumor suppressor in melanoma.
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    Immunoregulatory Protein B7-H3 Reprograms Glucose Metabolism in Cancer Cells by ROS-Mediated Stabilization of HIF1alpha.
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    T cell landscape in a primary melanoma predicts the survival of patients with metastatic disease after their treatment with dendritic cell vaccines.
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    PubMed     Text format     Abstract available


    March 2016
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    Early Adaptation and Acquired Resistance to CDK4/6 Inhibition in Estrogen Receptor-Positive Breast Cancer.
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  146. NIKOLAI BC, Lanz RB, York B, Dasgupta S, et al
    HER2 Signaling Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated Genes.
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  147. BOUSSEMART L, Girault I, Malka-Mahieu H, Mateus C, et al
    Secondary Tumors Arising in Patients Undergoing BRAF Inhibitor Therapy Exhibit Increased BRAF-CRAF Heterodimerization.
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  148. JONES LM, Broz ML, Ranger JJ, Ozcelik J, et al
    STAT3 Establishes an Immunosuppressive Microenvironment during the Early Stages of Breast Carcinogenesis to Promote Tumor Growth and Metastasis.
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  149. JOHNSON N, De Ieso P, Migliorini G, Orr N, et al
    Cytochrome P450 Allele CYP3A7*1C Associates with Adverse Outcomes in Chronic Lymphocytic Leukemia, Breast, and Lung Cancer.
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  150. HUH SJ, Oh H, Peterson MA, Almendro V, et al
    The proliferative activity of mammary epithelial cells in normal tissue predicts breast cancer risk in premenopausal women.
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  151. NAKANISHI Y, Walter K, Spoerke JM, O'Brien C, et al
    Activating Mutations in PIK3CB Confer Resistance to PI3K Inhibition and Define a Novel Oncogenic Role for p110beta.
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    February 2016
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    Cyclin E associates with the lipogenic enzyme ATP-citrate lyase to enable malignant growth of breast cancer cells.
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  153. JIANG YZ, Liu YR, Xu XE, Jin X, et al
    Transcriptome analysis of triple-negative breast cancer reveals an integrated mRNA-lncRNA signature with predictive and prognostic value.
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  154. DEN HOLLANDER P, Rawls K, Tsimelzon A, Shepherd J, et al
    Phosphatase PTP4A3 promotes triple-negative breast cancer growth and predicts poor patient survival.
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  155. SAHA S, Mukherjee S, Khan P, Kajal K, et al
    Aspirin suppresses the acquisition of chemo-resistance in breast cancer by disrupting an NFkappaB-IL6 signaling axis responsible for the generation of cancer stem cells.
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  156. NAKAJIMA K, Kho DH, Yanagawa T, Harazono Y, et al
    Galectin-3 cleavage alters bone remodeling: Different outcomes in breast and prostate cancer skeletal metastasis.
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  157. LU W, Ning H, Gu L, Peng H, et al
    MCPIP1 selectively destabilizes transcripts associated with an anti-apoptotic gene expression program in breast cancer cells that can elicit complete tumor regression.
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  158. YOUNGBLOOD VM, Kim LC, Edwards DN, Hwang Y, et al
    The ephrin-A1/EPHA2 signaling axis regulates glutamine metabolism in HER2-positive breast cancer.
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    January 2016
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    Breast Tumor Kinase (Brk/PTK6) is Induced by HIF, Glucocorticoid Receptor and PELP1 Mediated Stress Signaling in Triple-Negative Breast Cancer.
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  160. ZHAO W, Prijic S, Urban BC, Tisza MJ, et al
    Candidate anti-metastasis drugs suppress the metastatic capacity of breast cancer cells by reducing membrane fluidity.
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  161. BACCI M, Giannoni E, Fearns A, Ribas R, et al
    miR-155 drives metabolic reprogramming of ER+ breast cancer cells following long-term estrogen deprivation and predicts clinical response to aromatase inhibitors.
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  162. CAMP NJ, Lin WY, Bigelow A, Burghel GJ, et al
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  164. COX TR, Gartland A, Erler JT
    Lysyl Oxidase, a Targetable Secreted Molecule Involved in Cancer Metastasis.
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  165. TANAKA M, Shimamura S, Kuriyama S, Maeda D, et al
    SKAP2 Promotes Podosome Formation to Facilitate Tumor-Associated Macrophage Infiltration and Metastatic Progression.
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  166. LIM SO, Li CW, Xia W, Lee HH, et al
    EGFR signaling enhances aerobic glycolysis in triple negative breast cancer cells to promote tumor growth and immune escape.
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  167. LI CW, Xia W, Lim SO, Hsu JL, et al
    AKT1 inhibits epithelial-to-mesenchymal transition in breast cancer through phosphorylation-dependent Twist1 degradation.
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  168. ESPELIN CW, Leonard SC, Geretti E, Wickham TJ, et al
    Dual HER2 targeting with trastuzumab and liposome-encapsulated doxorubicin (MM-302) demonstrates synergistic antitumor activity in breast and gastric cancer.
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    December 2015
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    Treatment of Triple Negative Breast Cancer With TORC1/2 Inhibitors Sustains a Drug-resistant and Notch-dependent Cancer Stem Cell Population.
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    SSBP1 Suppresses TGF-beta-Driven Epithelial-to-Mesenchymal Transition and Metastasis in Triple-Negative Breast Cancer by Regulating Mitochondrial Retrograde Signaling.
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    November 2015
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    Imaging, biodistribution, and dosimetry of radionuclide-labeled PD-L1 antibody in an immunocompetent mouse model of breast cancer.
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