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Articles published in J Invest Dermatol

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Single Articles


    February 2023
  1. COULOMBE PA, Orosco A
    Inhibiting EGFR Signaling Holds Promise for Treating Palmoplantar Keratodermas.
    J Invest Dermatol. 2023;143:185-188.
    PubMed    


  2. SAPAO P, Roberson EDO, Shi B, Assassi S, et al
    Reduced SPAG17 Expression in Systemic Sclerosis Triggers Myofibroblast Transition and Drives Fibrosis.
    J Invest Dermatol. 2023;143:284-293.
    PubMed     Abstract available


  3. MEYER JM, Vavrova K, Radner FPW, Schneider H, et al
    ALOX12B and PNPLA1 Have Distinct Roles in Epidermal Lipid Lamellar Organization.
    J Invest Dermatol. 2023;143:332-335.
    PubMed    


  4. BASSET J, Marchal L, Hovnanian A
    EGFR Signaling Is Overactive in Pachyonychia Congenita: Effective Treatment with Oral Erlotinib.
    J Invest Dermatol. 2023;143:294-304.
    PubMed     Abstract available


  5. MACCHIARELLA G, Cornacchione V, Cojean C, Riker J, et al
    Disease Association of Anti‒Carboxyethyl Lysine Autoantibodies in Hidradenitis Suppurativa.
    J Invest Dermatol. 2023;143:273-283.
    PubMed     Abstract available


  6. HOLM NIELSEN S, Groen SS, Yao Y, Jorgensen AR, et al
    Biomarkers of Tissue Turnover and Systemic Inflammation Are Associated with Disease Severity and Activity in Patients with Hidradenitis Suppurativa.
    J Invest Dermatol. 2023;143:328-331.
    PubMed    


  7. HUDEMANN C, Exner Y, Pollmann R, Schneider K, et al
    IgG against the Membrane-Proximal Portion of the Desmoglein 3 Ectodomain Induces Loss of Keratinocyte Adhesion, a Hallmark in Pemphigus Vulgaris.
    J Invest Dermatol. 2023;143:254-263.
    PubMed     Abstract available


  8. RASSEK K, Izykowska K, Zurawek M, Nowicka K, et al
    TMEM244 Gene Expression as a Potential Blood Diagnostic Marker Distinguishing Sezary Syndrome from Mycosis Fungoides and Benign Erythroderma.
    J Invest Dermatol. 2023;143:344-347.
    PubMed    


  9. FANG H, Xue K, Cao T, Li Q, et al
    CXCL12/CXCR4 Axis Drives the Chemotaxis and Differentiation of B Cells in Bullous Pemphigoid.
    J Invest Dermatol. 2023;143:197-208.
    PubMed     Abstract available


    January 2023
  10. GUICHENEY M, Ducharme O, Caumont C, Gerard E, et al
    Assessment of liquid biopsy in primary cutaneous diffuse large B-Cell lymphoma- leg type.
    J Invest Dermatol. 2023 Jan 21:S0022-202X(23)00020.
    PubMed    


  11. SCHMIDT AD, Miciano C, Zheng Q, Mathyer ME, et al
    Involucrin modulates vitamin D receptor activity in the epidermis.
    J Invest Dermatol. 2023 Jan 12:S0022-202X(22)02903.
    PubMed     Abstract available


  12. DELLA BELLA C, Corra A, Mantengoli E, Galano A, et al
    Skin IL-17A and IFN-gamma production correlate with disease severity in patients with psoriasis and streptococcal infection.
    J Invest Dermatol. 2023 Jan 12:S0022-202X(22)02899.
    PubMed     Abstract available


  13. AGARWAL A, Orlow SJ
    Skin in the Game: An Analysis of Venture Capital Investment in Dermatology from 2002 to 2021.
    J Invest Dermatol. 2023 Jan 11:S0022-202X(22)02767.
    PubMed    


  14. NEMETH T, Balogh L, Kaposztas E, Szilveszter KP, et al
    Neutrophil-specific Syk expression is crucial for skin disease in experimental epidermolysis bullosa acquisita.
    J Invest Dermatol. 2023 Jan 11:S0022-202X(23)00010.
    PubMed     Abstract available


  15. KIM RW, An Y, Zukley L, Ferrucci L, et al
    Skin Barrier Function and Cognition Among Older Adults.
    J Invest Dermatol. 2023 Jan 11:S0022-202X(22)02897.
    PubMed    


  16. PADHI A, Rekha RS, Benrejdal L, Grundeken ME, et al
    Baricitinib blocks cytokine mediated downregulation of PAD1 in human keratinocytes: a possible molecular link to the effects of JAK-inhibitors in atopic dermatitis.
    J Invest Dermatol. 2023 Jan 11:S0022-202X(23)00001.
    PubMed    


  17. LUO L, Pasquali L, Srivastava A, Freisenhausen JC, et al
    The long non-coding RNA LINC00958 is induced in psoriasis epidermis and modulates epidermal proliferation.
    J Invest Dermatol. 2023 Jan 11:S0022-202X(22)02905.
    PubMed     Abstract available


  18. KANG T, Zhang C, Lei H, Luo R, et al
    NPTX2 Promotes EMT in Cutaneous Squamous Cell Carcinoma via Mettl3-Mediated m(6)A Methylation of Snail.
    J Invest Dermatol. 2023 Jan 10:S0022-202X(23)00009.
    PubMed     Abstract available


  19. MENG Q, Bai M, Guo M, Li Z, et al
    Inhibition of serum and glucocorticoid-regulated protein kinase-1 aggravates imiquimod-induced psoriatic dermatitis and enhances proinflammatory cytokine expression via the NF-kappaB pathway.
    J Invest Dermatol. 2023 Jan 6:S0022-202X(23)00007.
    PubMed     Abstract available


  20. GROLLEAU C, Calugareanu A, Demouche S, Nosbaum A, et al
    IL-4/IL-13 inhibitors for atopic dermatitis induce psoriatic rash transcriptionally close to pustular psoriasis.
    J Invest Dermatol. 2023 Jan 4:S0022-202X(22)02817.
    PubMed     Abstract available


  21. LIU W, Xu R, Wang F
    Recent Advances of Basophils in Pruritic Skin Diseases.
    J Invest Dermatol. 2023 Jan 4:S0022-202X(22)02889.
    PubMed     Abstract available


  22. ZHANG L, Qiu L, Wu J, Qi Y, et al
    GWAS of Chronic Spontaneous Urticaria Reveals Genetic Overlap with Autoimmune Diseases, Not Atopic Diseases.
    J Invest Dermatol. 2023;143:67-77.
    PubMed     Abstract available


  23. WALL D, Rees H, Bokhari L, Meah N, et al
    Signposts to the Promised Land in Alopecia Areata.
    J Invest Dermatol. 2023;143:9-10.
    PubMed    


  24. DE LOGU F, Maglie R, Titiz M, Poli G, et al
    miRNA-203b-3p Induces Acute and Chronic Pruritus through 5-HTR2B and TRPV4.
    J Invest Dermatol. 2023;143:142-153.
    PubMed     Abstract available


  25. AHMED MM, Rivas HG, Frost TC, DeCaprio JA, et al
    Distinct Radiation Responses in Virus-Positive and Virus-Negative Merkel Cell Carcinoma.
    J Invest Dermatol. 2023;143:166-169.
    PubMed    


  26. OLIVEIRA CB, Byrd AS, Okoye GA, Kaplan MJ, et al
    Neutralizing Anti‒DNase 1 and ‒DNase 1L3 Antibodies Impair Neutrophil Extracellular Traps Degradation in Hidradenitis Suppurativa.
    J Invest Dermatol. 2023;143:57-66.
    PubMed     Abstract available


  27. RAZA R, Chhabra G, Bilal M, Ndiaye MA, et al
    A Homozygous Missense Variant in K25 Underlying Overlapping Phenotype with Woolly Hair and Dental Anomalies.
    J Invest Dermatol. 2023;143:173-176.
    PubMed    


  28. CICHON MA, Elbe-Burger A
    Epidermal/Dermal Separation Techniques and Analysis of Cell Populations in Human Skin Sheets.
    J Invest Dermatol. 2023;143:11-17.
    PubMed     Abstract available


    December 2022
  29. HUFBAUER M, Rattay S, Hagen C, Quaas A, et al
    Poly(I:C) treatment prevents skin tumor formation in the preclinical HPV8 transgenic mouse model.
    J Invest Dermatol. 2022 Dec 27:S0022-202X(22)02900.
    PubMed     Abstract available


  30. NANRI Y, Nunomura S, Honda Y, Takedomi H, et al
    A positive loop formed by SOX11 and periostin upregulates TGF-beta signals leading to skin fibrosis.
    J Invest Dermatol. 2022 Dec 27:S0022-202X(22)02902.
    PubMed     Abstract available


  31. OLSSON-BROWN A, Yip V, Ogiji ED, Jolly C, et al
    TNF-alpha mediated keratinocyte expression and release of matrix metalloproteinase 9: putative mechanism of pathogenesis in Stevens-Johnson syndrome/ toxic epidermal necrolysis.
    J Invest Dermatol. 2022 Dec 26:S0022-202X(22)02898.
    PubMed     Abstract available


  32. POLUBOTHU S, Bender N, Muthiah S, Zecchin D, et al
    PTPN11 mosaicism causes a spectrum of pigmentary and vascular neurocutaneous disorders and predisposes to melanoma.
    J Invest Dermatol. 2022 Dec 22:S0022-202X(22)02891.
    PubMed     Abstract available


  33. LADA G, Chinoy H, Talbot PS, Warren RB, et al
    The Relationship of Depression and Systemic Inflammation in Psoriasis; Findings from the UK Biobank.
    J Invest Dermatol. 2022 Dec 22:S0022-202X(22)02894.
    PubMed    


  34. YI-PIN LEE C, Carissimo G, Teo TH, Ming Tong SJ, et al
    CD8+ T-cells trigger auricular dermatitis and blepharitis in mice post-Zika virus infection in the absence of CD4+ T-cells.
    J Invest Dermatol. 2022 Dec 22:S0022-202X(22)02893.
    PubMed     Abstract available


  35. CHIMBETETE T, Buck C, Choshi P, Selim R, et al
    HIV-Associated Immune Dysregulation in the Skin: A Crucible for Exaggerated Inflammation and Hypersensitivity.
    J Invest Dermatol. 2022 Dec 20:S0022-202X(22)02769.
    PubMed     Abstract available


  36. AFACH S, Le Cleach L, Sbidian E
    Placebo response in moderate-to-severe psoriasis: prevalence meta-analysis of randomised controlled trials.
    J Invest Dermatol. 2022 Dec 20:S0022-202X(22)02892.
    PubMed    


  37. GUPTA I, Shankrit S, Narta K, Ghazi M, et al
    Whole exome-sequencing of vitiligo lesions indicate lower burden of somatic variations: implications in risk for non-melanoma skin cancers.
    J Invest Dermatol. 2022 Dec 16:S0022-202X(22)02884.
    PubMed    


  38. TSAO CH, Hsieh WC, Lin FJ, Yang RY, et al
    The Critical Role of Galectin-12 in Modulating Lipid Metabolism in Sebaceous Glands.
    J Invest Dermatol. 2022 Dec 16:S0022-202X(22)02842.
    PubMed     Abstract available


  39. RANA I, Kataria S, Tan TL, Hajam EY, et al
    MINDIN (SPONDIN-2) IS ESSENTIAL FOR CUTANEOUS FIBROGENESIS IN A MOUSE MODEL OF SYSTEMIC SCLEROSIS.
    J Invest Dermatol. 2022 Dec 14:S0022-202X(22)02695.
    PubMed     Abstract available


  40. JAYASINGHE D, Betz-Stablein B, Stark MS, Soyer HP, et al
    Spatial Randomness in the distribution of acquired melanocytic naevi of the back in a population-based sample.
    J Invest Dermatol. 2022 Dec 13:S0022-202X(22)02843.
    PubMed    


  41. SUN J, Zhou J, Zhou J, Xu W, et al
    FGF4 promotes skin wound repair through p38 MAPK and GSK3beta-mediated stabilization of Slug.
    J Invest Dermatol. 2022 Dec 12:S0022-202X(22)02845.
    PubMed     Abstract available


  42. KARMON M, Kopel E, Barzilai A, Geva P, et al
    Altered RNA editing in Atopic Dermatitis highlights the role of dsRNA for immune surveillance.
    J Invest Dermatol. 2022 Dec 8:S0022-202X(22)02837.
    PubMed     Abstract available


  43. CHEN XY, Xu F, Chen JQ, Landeck L, et al
    UBE2L3 Reduces TRIM21 Expression and Interleukin-1beta Secretion in Epidermal Keratinocytes and Improves Psoriasis-like Skin.
    J Invest Dermatol. 2022 Dec 8:S0022-202X(22)02819.
    PubMed     Abstract available


  44. GONZALEZ JR, Celli A, Weckel A, Dhariwala MO, et al
    Filaggrin deficiency in mice alters the early life CD4(+) T cell response to skin commensal bacteria.
    J Invest Dermatol. 2022 Dec 7:S0022-202X(22)02822.
    PubMed     Abstract available


  45. HU T, Todberg T, Ewald DA, Hoof I, et al
    Assessment of Spatial and Temporal Variation in the Skin Transcriptome of Atopic Dermatitis by Use of 1.5 mm Mini Punch Biopsies.
    J Invest Dermatol. 2022 Dec 7:S0022-202X(22)02657.
    PubMed     Abstract available


  46. BORGOGNA C, Martuscelli L, Olivero C, Lo Cigno I, et al
    Enhanced Spontaneous Skin Tumorigenesis and Aberrant Inflammatory Response to UVB Exposure in Immunosuppressed HPV8 Transgenic Mice.
    J Invest Dermatol. 2022 Dec 5:S0022-202X(22)02829.
    PubMed     Abstract available


  47. MORISAKA H, Takaishi M, Akira S, Sano S, et al
    Keratinocyte Regnase-1, a down-regulator of skin inflammation, contributes to protection against tumor promotion by limiting COX-2 expression.
    J Invest Dermatol. 2022 Dec 2:S0022-202X(22)02827.
    PubMed     Abstract available


  48. PLAZYO O, Gudjonsson JE
    Hitting the Bullseye in Autoimmunity: Targeting Biologics through Tethering: Examining a Therapeutic Potential for Vitiligo and Beyond.
    J Invest Dermatol. 2022;142:3133-3135.
    PubMed    


  49. DUAN J, Grando C, Liu S, Chernyavsky A, et al
    The M3 Muscarinic Acetylcholine Receptor Promotes Epidermal Differentiation.
    J Invest Dermatol. 2022;142:3211-3221.
    PubMed     Abstract available


  50. JIANG M, Wang J, Shen Y, Zhu J, et al
    Ribosomal S6 Protein Kinase 2 Aggravates the Process of Systemic Scleroderma.
    J Invest Dermatol. 2022;142:3175-3183.
    PubMed     Abstract available


  51. PANDYA AG, Harris JE, Lebwohl M, Hamzavi IH, et al
    Addition of Narrow-Band UVB Phototherapy to Ruxolitinib Cream in Patients With Vitiligo.
    J Invest Dermatol. 2022;142:3352-3355.
    PubMed    


  52. HSUEH YC, Wang Y, Riding RL, Catalano DE, et al
    A Keratinocyte-Tethered Biologic Enables Location-Precise Treatment in Mouse Vitiligo.
    J Invest Dermatol. 2022;142:3294-3303.
    PubMed     Abstract available


  53. ZHAO L, Hsiao T, Stonesifer C, Daniels J, et al
    The Robust Tumoricidal Effects of Combined BET/HDAC Inhibition in Cutaneous T-Cell Lymphoma Can Be Reproduced by DeltaNp73 Depletion.
    J Invest Dermatol. 2022;142:3253-3261.
    PubMed     Abstract available


  54. BOCH K, Sharma A, Folberth J, Zillikens D, et al
    Distinct Metabolite Profile in Pemphigus Vulgaris.
    J Invest Dermatol. 2022;142:3327-3331.
    PubMed    


  55. RIETSCHER K, Jahnke HG, Rubsam M, Lin EW, et al
    Kinase Inhibition by PKC412 Prevents Epithelial Sheet Damage in Autosomal Dominant Epidermolysis Bullosa Simplex through Keratin and Cell Contact Stabilization.
    J Invest Dermatol. 2022;142:3282-3293.
    PubMed     Abstract available


  56. HEIM X, Bermudez J, Joshkon A, Kaspi E, et al
    CD146 at the Interface between Oxidative Stress and the Wnt Signaling Pathway in Systemic Sclerosis.
    J Invest Dermatol. 2022;142:3200-3210.
    PubMed     Abstract available


    November 2022
  57. LIU X, Li L, Jiang J, Ge W, et al
    The key role of CB1R in the sensory neurons to regulate psoriasiform skin inflammation and pruritus.
    J Invest Dermatol. 2022 Nov 18:S0022-202X(22)02770.
    PubMed     Abstract available


  58. DONG B, Simonson L, Vold S, Oldham E, et al
    Frizzled 6 promotes melanoma cell invasion but not proliferation by regulating canonical Wnt signaling and EMT.
    J Invest Dermatol. 2022 Nov 8. pii: S0022-202X(22)02660.
    PubMed     Abstract available


  59. KIM Y, Yin J, Le Breton S, Jorgenson E, et al
    Genetically Predicted Serum Vitamin C Levels and Cutaneous Squamous Cell Carcinoma Risk.
    J Invest Dermatol. 2022 Nov 4. pii: S0022-202X(22)02659.
    PubMed    


  60. ABDELAZEEM B, Abbas KS, Shehata J, Alfaar AS, et al
    Increased Risk of Subsequent Skin Melanoma in Patients with Retinoblastoma: SEER-Based Results.
    J Invest Dermatol. 2022;142:3123-3125.
    PubMed    


  61. PRIYA S, Kirschner LS
    Abnormal Fibroblasts Drive Pigmentary Skin Lesions in a Mouse Model of Carney Complex.
    J Invest Dermatol. 2022;142:2850-2852.
    PubMed    


  62. RAMCKE T, Bolduan V, Vicari E, Yilmaz K, et al
    Anti-BP230 Only Bullous Pemphigoid Constitutes a Distinct Disease Subgroup with Characteristic Serological and Clinical Features.
    J Invest Dermatol. 2022;142:3110-3113.
    PubMed    


  63. FANG X, Li M, He C, Liu Q, et al
    Plasma-Derived Exosomes in Chronic Spontaneous Urticaria Induce the Production of Mediators by Human Mast Cells.
    J Invest Dermatol. 2022;142:2998-3008.
    PubMed     Abstract available


  64. ROY S, Alkanfari I, Chaki S, Ali H, et al
    Role of MrgprB2 in Rosacea-Like Inflammation in Mice: Modulation by beta-Arrestin 2.
    J Invest Dermatol. 2022;142:2988-2997.
    PubMed     Abstract available


  65. SCHLEMEYER T, Ohnezeit D, Virdi S, Korner C, et al
    Merkel Cell Carcinoma and Immune Evasion: Merkel Cell Polyomavirus Small T-AntigenInduced Surface Changes Can Be Reverted by Therapeutic Intervention.
    J Invest Dermatol. 2022;142:3071-3081.
    PubMed     Abstract available


  66. SHAH P, Polsky D, Shao Y, Stein J, et al
    Patient- and County-Level Factors Associated with Late-Stage Merkel Cell Carcinoma at Diagnosis.
    J Invest Dermatol. 2022;142:3113-3117.
    PubMed    


  67. PICOZZA M, Cristofoletti C, Bresin A, Fioretti M, et al
    Genetically Driven CD39 Expression Affects Sezary Cell Viability and IL-2 Production and Detects Two Patient Subsets with Distinct Prognosis.
    J Invest Dermatol. 2022;142:3009-3019.
    PubMed     Abstract available


  68. HARMS PW, Chan MP, Bresler SC, Andea AA, et al
    Comment on "An Epidemiologic Analysis of Melanoma Overdiagnosis in the United States, 1975-2017".
    J Invest Dermatol. 2022;142:3120-3122.
    PubMed    


    October 2022
  69. CHEN C, Tang Y, Zhu X, Yang J, et al
    P311 promotes IL-4R-mediated M2 polarization of macrophages to enhance angiogenesis for efficient skin wound healing.
    J Invest Dermatol. 2022 Oct 26. pii: S0022-202X(22)02661.
    PubMed     Abstract available


  70. MICALI G, Verzi AE, Musumeci ML, Nardone B, et al
    NON-INVASIVE EVALUATION OF DIAMETER AND DENSITY OF DERMAL PAPILLAE IN PSORIATIC AND HEALTHY SKIN USING REFLECTANCE CONFOCAL MICROSCOPY: AN INTRAPATIENT CONTROLLED STUDY AND A REVIEW.
    J Invest Dermatol. 2022 Oct 20. pii: S0022-202X(22)02656.
    PubMed    


  71. LUU YT, Luo Q, Horner MJ, Shiels M, et al
    Risk of nonkeratinocyte skin cancers in people living with HIV during the era of antiretroviral therapy.
    J Invest Dermatol. 2022 Oct 7. pii: S0022-202X(22)01942.
    PubMed     Abstract available


  72. CAI KQ, Shellhamer C, Akiyama T, Jensen LE, et al
    Pellino1 restricts herpes simplex virus infections in the epidermis and dissemination to sebaceous glands.
    J Invest Dermatol. 2022 Oct 7. pii: S0022-202X(22)01941.
    PubMed    


  73. PINEIDER J, Eckert KM, McDonald JG, Harris-Tryon T, et al
    Cutaneous hormone production is distinct between anatomical sites and between males and females.
    J Invest Dermatol. 2022 Oct 5. pii: S0022-202X(22)02583.
    PubMed     Abstract available


  74. DIVINCENZO MJ, Schwarz E, Ren C, Barricklow Z, et al
    Expression patterns of microRNAs and associated target genes in ulcerated primary cutaneous melanoma.
    J Invest Dermatol. 2022 Oct 3. pii: S0022-202X(22)02640.
    PubMed     Abstract available


  75. WITTMANN M, Staubach P, McGonagle D
    Toward Cannabinoid Use for Refractory Cutaneous Dermatomyositis.
    J Invest Dermatol. 2022;142:2556-2557.
    PubMed    


  76. COUTIER J, Bonnette M, Martineau S, Mercadier A, et al
    Human-Induced Pluripotent Stem CellDerived Keratinocytes, a Useful Model to Identify and Explore the Pathological Phenotype of Epidermolysis Bullosa Simplex.
    J Invest Dermatol. 2022;142:2695-2705.
    PubMed     Abstract available


  77. FANG J, Ouyang M, Qu Y, Wang M, et al
    Advanced Glycation End Products Promote Melanogenesis by Activating NLRP3 Inflammasome in Human Dermal Fibroblasts.
    J Invest Dermatol. 2022;142:2591-2602.
    PubMed     Abstract available


  78. YANG F, Jiang X, Zhu Y, Lee M, et al
    Biallelic Variants in Lanosterol Synthase (LSS) Cause Palmoplantar Keratoderma-Congenital Alopecia Syndrome Type 2.
    J Invest Dermatol. 2022;142:2687-2694.
    PubMed     Abstract available


  79. YEO H, Ahn SS, Jung E, Lim Y, et al
    Transcription Factor EGR1 Regulates the Expression of the Clock Gene PER2 under IL-4 Stimulation in Human Keratinocytes.
    J Invest Dermatol. 2022;142:2677-2686.
    PubMed     Abstract available


  80. BRIDGEWOOD C, Wittmann M, Macleod T, Watad A, et al
    T Helper 2 IL-4/IL-13 Dual Blockade with Dupilumab Is Linked to Some Emergent T Helper 17Type Diseases, Including Seronegative Arthritis and Enthesitis/Enthesopathy, but Not to Humoral Autoimmune Diseases.
    J Invest Dermatol. 2022;142:2660-2667.
    PubMed     Abstract available


  81. GARTIN AK, Frost TC, Cushman CH, Leeper BA, et al
    Merkel Cell Carcinoma Sensitivity to EZH2 Inhibition Is Mediated by SIX1 Derepression.
    J Invest Dermatol. 2022;142:2783-2792.
    PubMed     Abstract available


  82. SENNA M, Ko J, Glashofer M, Walker C, et al
    Predictors of QOL in Patients with Alopecia Areata.
    J Invest Dermatol. 2022;142:2646-2650.
    PubMed     Abstract available


  83. SEILER DL, Kleingarn M, Kahler KH, Gruner C, et al
    C5aR2 Deficiency Ameliorates Inflammation in Murine Epidermolysis Bullosa Acquisita by Regulating Fcgamma Receptor Expression on Neutrophils.
    J Invest Dermatol. 2022;142:2715-2723.
    PubMed     Abstract available


  84. SHANG W, Tan AYQ, van Steensel MAM, Lim X, et al
    Aberrant Wnt Signaling Induces Comedo-Like Changes in the Murine Upper Hair Follicle.
    J Invest Dermatol. 2022;142:2603-2612.
    PubMed     Abstract available


    September 2022
  85. SHI B, Tsou PS, Ma F, Mariani MP, et al
    Senescent cells accumulate in systemic sclerosis skin.
    J Invest Dermatol. 2022 Sep 30. pii: S0022-202X(22)02637.
    PubMed    


  86. KIM J, He Y, Tormen S, Kleindienst P, et al
    The p300/CBP inhibitor A485 normalizes psoriatic fibroblast gene expression in vitro and reduces psoriasis-like skin inflammation in vivo.
    J Invest Dermatol. 2022 Sep 26. pii: S0022-202X(22)01937.
    PubMed     Abstract available


  87. SILVA-VILCHES C, Bolduan V, Alabdullah M, Steinbrink K, et al
    Topical application of adenosine A2-type receptor agonists prevents contact hypersensitivity reactions in mice by affecting skin dendritic cells.
    J Invest Dermatol. 2022 Sep 26. pii: S0022-202X(22)01908.
    PubMed     Abstract available


  88. CHAKRABORTY A, Perez M, Carroll JD, Antonopoulos A, et al
    Hypoxia controls the glycome signature and galectin-8 - ligand axis to promote pro-tumorigenic properties of metastatic melanoma.
    J Invest Dermatol. 2022 Sep 26. pii: S0022-202X(22)01931.
    PubMed     Abstract available


  89. ZHANG Y, LeWitt TM, Louissaint A Jr, Guitart J, et al
    Disease-Defining Molecular Features of Primary Cutaneous B-Cell Lymphomas: Implications for Classification and Treatment.
    J Invest Dermatol. 2022 Sep 24. pii: S0022-202X(22)01887.
    PubMed     Abstract available


  90. WU H, Ke X, Huang W, Shi W, et al
    Multi-Tissue Integrative Analysis Identifies Susceptibility Genes for Atopic Dermatitis.
    J Invest Dermatol. 2022 Sep 22. pii: S0022-202X(22)01940.
    PubMed     Abstract available


  91. GRANTHAM HJ, Hussain AB, Reynolds NJ
    Serum S100A8/A9 May Act as Biomarker of Atherosclerosis Severity in Psoriasis.
    J Invest Dermatol. 2022 Sep 16. pii: S0022-202X(22)01670.
    PubMed    


  92. KREUGER IZM, Slieker RC, van Groningen T, van Doorn R, et al
    Therapeutic Strategies for Targeting CDKN2A Loss in Melanoma.
    J Invest Dermatol. 2022 Sep 16. pii: S0022-202X(22)01769.
    PubMed     Abstract available


  93. YAN Y, Tian J, Wang Y, Li Y, et al
    Transcriptomic heterogeneity of skin across different anatomic sites.
    J Invest Dermatol. 2022 Sep 16. pii: S0022-202X(22)01932.
    PubMed     Abstract available


  94. KOCH M, Kockmann T, Rodriguez E, Wehkamp U, et al
    Quantitative proteomics identifies reduced NRF2 activity and mitochondrial dysfunction in Atopic Dermatitis.
    J Invest Dermatol. 2022 Sep 12. pii: S0022-202X(22)01904.
    PubMed     Abstract available


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    Thioredoxin Reductase 1 Modulates Pigmentation and Photobiology of Murine Melanocytes in vivo.
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    Prognostic Utility of CpG Island Hypermethylated Phenotype in Early-Stage Invasive Primary Melanomas.
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    Skin Deep: The Role of the Microbiota in Cutaneous Autoimmunity.
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    Therapeutic Potential of Nitric Oxide releasing Selective Estrogen Receptor Modulators (NO-SERMs) in Malignant Melanoma.
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    The Sensation of Itch: From Biological Discovery to Medical Treatment.
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    The Role of CNTNAP2 in Itch Sensation.
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  305. HANSEN UK, Lyngaa R, Ibrani D, Church C, et al
    Extended T-Cell Epitope Landscape in Merkel Cell Polyomavirus Large T and Small T Oncoproteins Identified Uniquely in Patients with Cancer.
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    Nuclear IL-33 Plays an Important Role in IL-31Mediated Downregulation of FLG, Keratin 1, and Keratin 10 by Regulating Signal Transducer and Activator of Transcription 3 Activation in Human Keratinocytes.
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    December 2021
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    Transcriptomes of MPO-deficient patients with generalized pustular psoriasis reveals expansion of CD4+ cytotoxic T cells and an involvement of the complement system.
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    Mouse Models of Psoriasis: A Comprehensive Review.
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  312. CHONG BF, Werth V
    Cutaneous Lupus Erythematosus and Dermatomyositis: Utilizing Assessment Tools for Treatment Efficacy.
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  319. HIROYASU S, Tsuruta D
    Stabilization of Hemidesmosomal Proteins: A Possible Key Contributor to Wnt/beta-Catenin Pathway Action in the Skin.
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    Aging Associated Changes in the Adult Human Skin Microbiome and the Host Factors That Affect Skin Microbiome Composition.
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    BRAF Inhibitors in Melanoma Management: When Friends Become Foes.
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  325. MUSE ME, Bergman DT, Salas LA, Tom LN, et al
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    UDP-GlcNAc-1-Phosphotransferase Is a Clinically Important Regulator of Human and Mouse Hair Pigmentation.
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  336. SEVIIRI M, Law MH, Ong JS, Gharahkhani P, et al
    Polygenic Risk Scores Stratify Keratinocyte Cancer Risk among Solid Organ Transplant Recipients with Chronic Immunosuppression in a High Ultraviolet Radiation Environment.
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    Abdominal visceral adiposity is associated with coronary artery lipid-rich necrotic core partly mediated by bone marrow uptake of (18)F-FDG PET / CT in psoriasis.
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    Recalcitrant Warts, Epidermodysplasia Verruciformis, and the Tree-Man Syndrome: Phenotypic Spectrum of Cutaneous HPV Infections at the Intersection of Genetic Variability of Viral and Human Genomes.
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    Loss of integrin alpha9beta1 on tumor keratinocytes enhances the stromal vasculature and growth of cutaneous tumors.
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    IL-13Ralpha1 Suppresses Tumor Progression in Two-stage Skin Carcinogenesis Model by Regulating Regulatory T Cells.
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    New Key Players in Irritant Contact Dermatitis: Residential Skin Cells and Neutrophils Drive Inflammation.
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    Down-Regulated Calcium-Sensing Receptor in Keratinocytes and Skin from Aged Mice and Humans Impairs Function.
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  361. BALMERT SC, Ghozloujeh ZG, Carey CD, Akilov OE, et al
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  369. OLSEN CM, Pandeya N, Whiteman DC
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    Repurposing melanoma chemotherapy to activate inflammasomes in treatment of BRAF/MAPK inhibitor resistant melanoma.
    J Invest Dermatol. 2021 Oct 22. pii: S0022-202X(21)02384.
    PubMed     Abstract available


  382. AL RAHMOUN M, Ghiasvand R, Cairat M, Mahamat-Saleh Y, et al
    Statin Use and Skin Cancer Risk: A Prospective Cohort Study.
    J Invest Dermatol. 2021 Oct 22. pii: S0022-202X(21)02382.
    PubMed     Abstract available


  383. KONG HH, Oh J
    State of residency: microbial strain diversity in the skin.
    J Invest Dermatol. 2021 Oct 21. pii: S0022-202X(21)02351.
    PubMed     Abstract available


  384. NJAUW CN, Ji Z, Pham DM, Simoneau A, et al
    Oncogenic KIT Induces Replication stress and Confers Cell Cycle Checkpoint Vulnerability in Melanoma.
    J Invest Dermatol. 2021 Oct 20. pii: S0022-202X(21)02347.
    PubMed     Abstract available


  385. JANDOVA J, Wondrak GT
    Vemurafenib drives EMT gene expression in BRAFi-resistant BRAF(V600E)/NRAS(Q61K) melanoma enhancing tumor growth and metastasis in a bioluminescent murine model.
    J Invest Dermatol. 2021 Oct 20. pii: S0022-202X(21)02368.
    PubMed     Abstract available


  386. XUE K, Shao S, Fang H, Ma L, et al
    Adipocyte-derived C1q-TNF-related Protein 3 Exhibits Anti-inflammatory effects via LAMP1-STAT3 axis in Psoriasis.
    J Invest Dermatol. 2021 Oct 20. pii: S0022-202X(21)02369.
    PubMed     Abstract available


  387. GARCIA-DIAZ N, Casar B, Alonso-Alonso R, Quevedo L, et al
    PLCgamma1/PKCtheta Downstream Signaling Controls Cutaneous T-Cell Lymphoma Development And Progression.
    J Invest Dermatol. 2021 Oct 20. pii: S0022-202X(21)02350.
    PubMed     Abstract available


  388. NAGORE E, Viros A, Kumar R
    Positive Attributes of Anti-TERT CD4 T-Helper Type 1 Immune Responses in Melanoma.
    J Invest Dermatol. 2021 Oct 16. pii: S0022-202X(21)02269.
    PubMed     Abstract available


  389. CHILIBROSTE S, Monaco A, Plata MC, Vola M, et al
    Preclinical evaluation of LVR01 attenuated Salmonella as neoadjuvant intralesional therapy in combination with chemotherapy for melanoma treatment.
    J Invest Dermatol. 2021 Oct 15. pii: S0022-202X(21)02317.
    PubMed     Abstract available


  390. MARTINS C, Migayron L, Drullion C, Jacquemin C, et al
    Vitiligo skin T cells are prone to produce type 1- and type 2-cytokines to induce melanocyte dysfunction and epidermal inflammatory response through JAK signaling.
    J Invest Dermatol. 2021 Oct 13. pii: S0022-202X(21)02304.
    PubMed     Abstract available


  391. SEO JY, You SW, Shin JG, Kim Y, et al
    Genome-wide association study identifies multiple genetic loci for skin color in Korean women.
    J Invest Dermatol. 2021 Oct 11. pii: S0022-202X(21)02303.
    PubMed     Abstract available


  392. RAVIPATI A, Nolan S, Alphonse M, Dikeman D, et al
    IL-6R/STAT3-signaling in keratinocytes rather than T cells induces psoriasis-like dermatitis in mice.
    J Invest Dermatol. 2021 Oct 6. pii: S0022-202X(21)02291.
    PubMed     Abstract available


  393. CASTILLO R, Subudhi I, Naik S
    Fanning the Flames: IRAK2 Signaling in Differentiated Epithelium Potentiates Skin Inflammation.
    J Invest Dermatol. 2021;141:2325-2327.
    PubMed     Abstract available


  394. AZIN M, Demehri S
    Innate Lymphoid Cells: New Targets for Cutaneous Squamous Cell Carcinoma Immunotherapy.
    J Invest Dermatol. 2021;141:2320-2322.
    PubMed     Abstract available


  395. YANG R, Wang RC
    Research Techniques Made Simple: Studying Circular RNA in Skin Diseases.
    J Invest Dermatol. 2021;141:2313-2319.
    PubMed     Abstract available


  396. SIEBERT S, Sattar N
    Estimating Cardiovascular Impacts of Drugs for Psoriatic Disease: A Long Way to Go.
    J Invest Dermatol. 2021;141:2322-2325.
    PubMed     Abstract available


  397. HASHIMOTO T, Mishra SK, Olivry T, Yosipovitch G, et al
    Periostin, an Emerging Player in Itch Sensation.
    J Invest Dermatol. 2021;141:2338-2343.
    PubMed     Abstract available


  398. YAN D, Blauvelt A, Dey AK, Golpanian RS, et al
    New Frontiers in Psoriatic Disease Research, Part II: Comorbidities and Targeted Therapies.
    J Invest Dermatol. 2021;141:2328-2337.
    PubMed     Abstract available


  399. SHAO S, Tsoi LC, Swindell WR, Chen J, et al
    IRAK2 Has a Critical Role in Promoting Feed-Forward Amplification of Epidermal Inflammatory Responses.
    J Invest Dermatol. 2021;141:2436-2448.
    PubMed     Abstract available


  400. NORIMATSU Y, Yoshizaki A, Kabeya Y, Fukasawa T, et al
    Expert-Level Distinction of Systemic Sclerosis from Hand Photographs Using Deep Convolutional Neural Networks.
    J Invest Dermatol. 2021;141:2536-2539.
    PubMed    


  401. WONGVIBULSIN S, Sutaria N, Williams KA, Huang AH, et al
    A Nationwide Study of Prurigo Nodularis: Disease Burden and Healthcare Utilization in the United States.
    J Invest Dermatol. 2021;141:2530-2533.
    PubMed    


  402. CAO L, Yue X, Zhao Y, Du L, et al
    Mechanisms of Broad-Band UVB IrradiationInduced Itch in Mice.
    J Invest Dermatol. 2021;141:2499-2508.
    PubMed     Abstract available


    September 2021
  403. VAN HOVE L, Hoste E
    Activation of fibroblasts in skin cancer.
    J Invest Dermatol. 2021 Sep 30. pii: S0022-202X(21)02289.
    PubMed     Abstract available


  404. CHHABRA G, Singh CK, Guzman-Perez G, Ndiaye MA, et al
    Anti-melanoma effects of concomitant inhibition of SIRT1 and SIRT3 in Braf(V600E)/Pten(NULL) mice.
    J Invest Dermatol. 2021 Sep 28. pii: S0022-202X(21)02223.
    PubMed     Abstract available


  405. XU T, Dai J, Tang L, Yang L, et al
    EZH2 inhibitor enhances the STING agonist-induced antitumor immunity in melanoma.
    J Invest Dermatol. 2021 Sep 24. pii: S0022-202X(21)02227.
    PubMed     Abstract available


  406. BEATTIE K, Jiang H, Gautam M, MacVittie MK, et al
    TRPC3 Antagonizes Pruritus in A Mouse Contact Dermatitis Model.
    J Invest Dermatol. 2021 Sep 24. pii: S0022-202X(21)02222.
    PubMed     Abstract available


  407. WANG F, Luo Q, Chen Y, Liu Y, et al
    A genome-wide scan on individual typology angle found variants at SLC24A2 associated with skin color variation in Chinese populations.
    J Invest Dermatol. 2021 Sep 24. pii: S0022-202X(21)02226.
    PubMed    


  408. MAURO TM
    Ode to Salt: Commentary on "Skin Sodium Accumulates in Psoriasis and Reflects Disease Severity".
    J Invest Dermatol. 2021 Sep 24. pii: S0022-202X(21)02174.
    PubMed     Abstract available


  409. HAILFINGER S, Schulze-Osthoff K
    Impaired Autophagy in Psoriasis and Atopic Dermatitis: A New Therapeutic Target?
    J Invest Dermatol. 2021 Sep 23. pii: S0022-202X(21)01409.
    PubMed     Abstract available


  410. GARZORZ-STARK N, Eyerich K
    IFN-1s: Sentinels Shaping Distinct Immune Responses in Skin.
    J Invest Dermatol. 2021 Sep 23. pii: S0022-202X(21)01668.
    PubMed     Abstract available


  411. EMMONS MF, Smalley KSM
    Ironing-Out the Details: New Strategies for Combining Ferroptosis Inhibitors with Immunotherapy in Melanoma.
    J Invest Dermatol. 2021 Sep 23. pii: S0022-202X(21)01436.
    PubMed     Abstract available


  412. ADELMANN CH, Rachmin I, Fisher DE
    MFN2 Stabilization: A Bridge for Endoplasmic Reticulum Stress Sensitivity in Melanoma.
    J Invest Dermatol. 2021 Sep 23. pii: S0022-202X(21)01224.
    PubMed     Abstract available


  413. PANDIYAN P, McCormick TS
    Regulation of IL-17A-Producing Cells in Skin Inflammatory Disorders.
    J Invest Dermatol. 2021 Sep 21. pii: S0022-202X(21)01673.
    PubMed     Abstract available


  414. ALLMEROTH K, Denzel MS
    The RATIOnal Role of Polyamines in Epidermal Differentiation.
    J Invest Dermatol. 2021;141:2105-2107.
    PubMed     Abstract available


  415. YAN D, Gudjonsson JE, Le S, Maverakis E, et al
    New Frontiers in Psoriatic Disease Research, Part I: Genetics, Environmental Triggers, Immunology, Pathophysiology, and Precision Medicine.
    J Invest Dermatol. 2021;141:2112-2122.
    PubMed     Abstract available


  416. NAVRAZHINA K, Garcet S, Gonzalez J, Grand D, et al
    In-Depth Analysis of the Hidradenitis Suppurativa Serum Proteome Identifies Distinct Inflammatory Subtypes.
    J Invest Dermatol. 2021;141:2197-2207.
    PubMed     Abstract available


  417. MAHO-VAILLANT M, Perals C, Golinski ML, Hebert V, et al
    Rituximab and Corticosteroid Effect on Desmoglein-Specific B Cells and Desmoglein-Specific T Follicular Helper Cells in Pemphigus.
    J Invest Dermatol. 2021;141:2132-2140.
    PubMed     Abstract available


  418. KOGA H, Teye K, Otsuji Y, Ishii N, et al
    Autoantibodies to DSC3 in Pemphigus Exclusively Recognize Calcium-Dependent Epitope in Extracellular Domain 2.
    J Invest Dermatol. 2021;141:2123-2131.
    PubMed     Abstract available


  419. HABAULT J, Thonnart N, Pasquereau-Kotula E, Bagot M, et al
    PAK1-Dependent Antitumor Effect of AAC-11Derived Peptides on Sezary Syndrome Malignant CD4(+) T Lymphocytes.
    J Invest Dermatol. 2021;141:2261-2271.
    PubMed     Abstract available


  420. ZOU Y, Yuan H, Zhou S, Zhou Y, et al
    The Pathogenic Role of CD4(+) Tissue-Resident Memory T Cells Bearing T Follicular Helper-Like Phenotype in Pemphigus Lesions.
    J Invest Dermatol. 2021;141:2141-2150.
    PubMed     Abstract available


    August 2021
  421. LAHMAN MC, Paulson KG, Nghiem PT, Chapuis AG, et al
    Quality Is King: Fundamental Insights into Tumor Antigenicity from Virus-Associated Merkel Cell Carcinoma.
    J Invest Dermatol. 2021;141:1897-1905.
    PubMed     Abstract available


  422. VELLAICHAMY G, Dimitrion P, Zhou L, Ozog D, et al
    Insights from gamma-Secretase: Functional Genetics of Hidradenitis Suppurativa.
    J Invest Dermatol. 2021;141:1888-1896.
    PubMed     Abstract available


  423. OTOTAKE Y, Yamaguchi Y, Asami M, Komitsu N, et al
    Downregulated IRF8 in Monocytes and Macrophages of Patients with Systemic Sclerosis May Aggravate the Fibrotic Phenotype.
    J Invest Dermatol. 2021;141:1954-1963.
    PubMed     Abstract available


  424. LIAO WT, Hung CH, Liang SS, Yu S, et al
    Anti-Inflammatory Effects Induced by Near-Infrared Light Irradiation through M2 Macrophage Polarization.
    J Invest Dermatol. 2021;141:2056-2066.
    PubMed     Abstract available


  425. SONG Z, Chen X, Zhao Q, Stanic V, et al
    Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes.
    J Invest Dermatol. 2021;141:1964-1974.
    PubMed     Abstract available


  426. CHEN KL, Patel J, Zeidi M, Wysocka M, et al
    Myeloid Dendritic Cells Are Major Producers of IFN-beta in Dermatomyositis and May Contribute to Hydroxychloroquine Refractoriness.
    J Invest Dermatol. 2021;141:1906-1914.
    PubMed     Abstract available


  427. SHI C, Ray-Jones H, Ding J, Duffus K, et al
    Chromatin Looping Links Target Genes with Genetic Risk Loci for Dermatological Traits.
    J Invest Dermatol. 2021;141:1975-1984.
    PubMed     Abstract available


  428. SAMRA EB, Mahe YF, Le Balch M, Cavusoglu N, et al
    Transcriptome Profiling of Pilosebaceous Units in Male Androgenetic Alopecia Reveals Altered Junctional Networks.
    J Invest Dermatol. 2021;141:2070-2073.
    PubMed    


    July 2021
  429. HEDBERG M, Seykora JT
    Clarifying Progress on the Genomic Landscape of Actinic Keratosis.
    J Invest Dermatol. 2021;141:1622-1624.
    PubMed     Abstract available


  430. SCHILF P, Schmitz M, Derenda-Hell A, Thieme M, et al
    Inhibition of Glucose Metabolism Abrogates the Effector Phase of Bullous Pemphigoid-Like Epidermolysis Bullosa Acquisita.
    J Invest Dermatol. 2021;141:1646-1655.
    PubMed     Abstract available


  431. WIENHOLTZ NKF, Christensen CE, Coskun H, Zhang DG, et al
    Infusion of Pituitary Adenylate Cyclase-Activating Polypeptide-38 in Patients with Rosacea Induces Flushing and Facial Edema that Can Be Attenuated by Sumatriptan.
    J Invest Dermatol. 2021;141:1687-1698.
    PubMed     Abstract available


  432. GRAVEMEYER J, Lange A, Ritter C, Spassova I, et al
    Classical and Variant Merkel Cell Carcinoma Cell Lines Display Different Degrees of Neuroendocrine Differentiation and Epithelial-Mesenchymal Transition.
    J Invest Dermatol. 2021;141:1675-1686.
    PubMed     Abstract available


  433. SENESCHAL J, Duplaine A, Maillard H, Passeron T, et al
    Efficacy and Safety of Tacrolimus 0.1% for the Treatment of Facial Vitiligo: A Multicenter Randomized, Double-Blinded, Vehicle-Controlled Study.
    J Invest Dermatol. 2021;141:1728-1734.
    PubMed     Abstract available


  434. LIPOVSKY A, Slivka PF, Su Z, Wang Y, et al
    ACT1 Is Required for Murine IL-23-Induced Psoriasiform Inflammation Potentially Independent of E3 Ligase Activity.
    J Invest Dermatol. 2021;141:1772-1779.
    PubMed     Abstract available


  435. ZHU Y, Mitra N, Feng Y, Tishkoff S, et al
    FLG Variation Differs between European Americans and African Americans.
    J Invest Dermatol. 2021;141:1855-1857.
    PubMed    


  436. LYUBCHENKO T, Collins HK, Vang KA, Leung DYM, et al
    SMOC1 and IL-4 and IL-13 Cytokines Interfere with Ca(2+) Mobilization in Primary Human Keratinocytes.
    J Invest Dermatol. 2021;141:1792-1801.
    PubMed     Abstract available


  437. THOMSON J, Bewicke-Copley F, Anene CA, Gulati A, et al
    The Genomic Landscape of Actinic Keratosis.
    J Invest Dermatol. 2021;141:1664-1674.
    PubMed     Abstract available


  438. SOLA-ORTIGOSA J, Munoz-Santos C, Otzet-Gramunt I, Masat-Tico T, et al
    The Usefulness of Teledermatology in Monitoring the Efficacy and Safety of a Topical Treatment for Actinic Keratosis.
    J Invest Dermatol. 2021;141:1837-1839.
    PubMed    


  439. HOJMAN L, Cabrera R, Karsulovic C, Tempio F, et al
    The Role of CXCL10 and IL-18 as Markers of Repigmentation Response in Nonsegmental Vitiligo Treated with Narrowband UVB Phototherapy: A Prospective Cohort Study.
    J Invest Dermatol. 2021;141:1833-1836.
    PubMed    


  440. CHO SI, Yu DA, Kim SI, Lee SM, et al
    Pregnancy Outcomes in Female Patients with Alopecia Areata: A Nationwide Population-Based Study.
    J Invest Dermatol. 2021;141:1844-1847.
    PubMed    


  441. YOUSSEFIAN L, Niaziorimi F, Saeidian AH, South AP, et al
    Knockdown of SDR9C7 Impairs Epidermal Barrier Function.
    J Invest Dermatol. 2021;141:1754-1764.
    PubMed     Abstract available


  442. YU Q, Parajuli N, Yi Q, Mishina Y, et al
    ALK3 Is Not Required for the Embryonic Development, Homeostasis, and Repopulation of Epidermal Langerhans Cells in Steady and Inflammatory States.
    J Invest Dermatol. 2021;141:1858-1861.
    PubMed    


    June 2021
  443. MURASE C, Takeichi T, Nomura T, Ogi T, et al
    Hereditary Mucoepithelial Dysplasia and Autosomal-Dominant IFAP Syndrome Is a Clinical Spectrum Due to SREBF1 Variants.
    J Invest Dermatol. 2021;141:1596-1598.
    PubMed    


  444. SHI H, Smits JPH, van den Bogaard EH, Brewer MG, et al
    Research Techniques Made Simple: Delivery of the CRISPR/Cas9 Components into Epidermal Cells.
    J Invest Dermatol. 2021;141:1375-1381.
    PubMed     Abstract available


  445. AKASAKA E, Kleiser S, Sengle G, Bruckner-Tuderman L, et al
    Diversity of Mechanisms Underlying Latent TGF-beta Activation in Recessive Dystrophic Epidermolysis Bullosa.
    J Invest Dermatol. 2021;141:1450-1460.
    PubMed     Abstract available


  446. TAN MWY, Tan WR, Kong ZQ, Toh JH, et al
    High Glucose Restraint of Acetylcholine-Induced Keratinocyte Epithelial-Mesenchymal Transition Is Mitigated by p38 Inhibition.
    J Invest Dermatol. 2021;141:1438-1449.
    PubMed     Abstract available


  447. ZHAO J, Yang S, Shu B, Chen L, et al
    Transient High Glucose Causes Persistent Vascular Dysfunction and Delayed Wound Healing by the DNMT1-Mediated Ang-1/NF-kappaB Pathway.
    J Invest Dermatol. 2021;141:1573-1584.
    PubMed     Abstract available


  448. WU KY, Kim S, Liu VM, Sabino A, et al
    Function-Blocking RHAMM Peptides Attenuate Fibrosis and Promote Antifibrotic Adipokines in a Bleomycin-Induced Murine Model of Systemic Sclerosis.
    J Invest Dermatol. 2021;141:1482-1492.
    PubMed     Abstract available


  449. BIENZ MN, Petrogiannis-Haliotis T, Pehr K, Benlimame N, et al
    Three-Dimensional Telomeric Fingerprint of Mycosis Fungoides and/or Sezary Syndrome: A Pilot Study.
    J Invest Dermatol. 2021;141:1598-1601.
    PubMed    


  450. KOBAYASHI K, Kamekura R, Kato J, Kamiya S, et al
    Cigarette Smoke Underlies the Pathogenesis of Palmoplantar Pustulosis via an IL-17A-Induced Production of IL-36gamma in Tonsillar Epithelial Cells.
    J Invest Dermatol. 2021;141:1533-1541.
    PubMed     Abstract available


  451. DE GROOT R, Bosma AL, Cornet R, Spuls PI, et al
    The Selection Process for a Web-Based Application to Measure Patient-Reported Outcomes Following the Example of the TREAT NL Registry.
    J Invest Dermatol. 2021;141:1592-1595.
    PubMed    


    May 2021
  452. NOE MH
    Understanding Epidermal Necrolysis after the Initial Hospitalization.
    J Invest Dermatol. 2021;141:1139-1140.
    PubMed     Abstract available


  453. KIRBY JS
    Unraveling the Heterogeneity of Hidradenitis Suppurativa with Phenotype Schema.
    J Invest Dermatol. 2021;141:1136-1138.
    PubMed     Abstract available


  454. LUO H, Faghankhani M, Cao Y, Uitto J, et al
    Molecular Genetics and Modifier Genes in Pseudoxanthoma Elasticum, a Heritable Multisystem Ectopic Mineralization Disorder.
    J Invest Dermatol. 2021;141:1148-1156.
    PubMed     Abstract available


  455. BOURSIER G, Piram M, Rittore C, Sarrabay G, et al
    Phenotypic Associations of PSTPIP1 Sequence Variants in PSTPIP1-Associated Autoinflammatory Diseases.
    J Invest Dermatol. 2021;141:1141-1147.
    PubMed     Abstract available


  456. YAO Q, Epstein CB, Banskota S, Issner R, et al
    Epigenetic Alterations in Keratinocyte Carcinoma.
    J Invest Dermatol. 2021;141:1207-1218.
    PubMed     Abstract available


  457. CAZZANIGA S, Pezzolo E, Bettoli V, Abeni D, et al
    Characterization of Hidradenitis Suppurativa Phenotypes: A Multidimensional Latent Class Analysis of the National Italian Registry IRHIS.
    J Invest Dermatol. 2021;141:1236-1242.
    PubMed     Abstract available


  458. WANG Z, Yoo YJ, De La Torre R, Topham C, et al
    Inverse Correlation of TRIM32 and Protein Kinase C zeta in T Helper Type 2-Biased Inflammation.
    J Invest Dermatol. 2021;141:1297-1307.
    PubMed     Abstract available


  459. PU W, Wu W, Liu Q, Ma Y, et al
    Exome-Wide Association Analysis Suggests LRP2BP as a Susceptibility Gene for Endothelial Injury in Systemic Sclerosis in the Han Chinese Population.
    J Invest Dermatol. 2021;141:1254-1263.
    PubMed     Abstract available


  460. MAKITA E, Matsuzaki Y, Fukui T, Matsui A, et al
    Autoantibodies to BPAG1e Trigger Experimental Bullous Pemphigoid in Mice.
    J Invest Dermatol. 2021;141:1167-1176.
    PubMed     Abstract available


    April 2021
  461. OKAMURA K, Garber M, Harris JE
    Gaining Insight into Vitiligo Genetics through the Lens of a Large Epidemiologic Study.
    J Invest Dermatol. 2021;141:718-721.
    PubMed     Abstract available


  462. VEENSTRA J, Dimitrion P, Yao Y, Zhou L, et al
    Research Techniques Made Simple: Use of Imaging Mass Cytometry for Dermatological Research and Clinical Applications.
    J Invest Dermatol. 2021;141:705-712.
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  463. CHAO-CHU J, Murtough S, Zaman N, Pennington DJ, et al
    iRHOM2: A Regulator of Palmoplantar Biology, Inflammation, and Viral Susceptibility.
    J Invest Dermatol. 2021;141:722-726.
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  464. JACKOW J, Rami A, Hayashi R, Hansen C, et al
    Targeting the Jak/Signal Transducer and Activator of Transcription 3 Pathway with Ruxolitinib in a Mouse Model of Recessive Dystrophic Epidermolysis Bullosa-Squamous Cell Carcinoma.
    J Invest Dermatol. 2021;141:942-946.
    PubMed    


  465. LIU X, Wang Y, Tao T, Zeng L, et al
    GRPR/Extracellular Signal-Regulated Kinase and NPRA/Extracellular Signal-Regulated Kinase Signaling Pathways Play a Critical Role in Spinal Transmission of Chronic Itch.
    J Invest Dermatol. 2021;141:863-873.
    PubMed     Abstract available


  466. BRAUWEILER AM, Leung DYM, Goleva E
    The Transcription Factor p63 Is a Direct Effector of IL-4- and IL-13-Mediated Repression of Keratinocyte Differentiation.
    J Invest Dermatol. 2021;141:770-778.
    PubMed     Abstract available


  467. SONG L, Bretz AC, Gravemeyer J, Spassova I, et al
    The HDAC Inhibitor Domatinostat Promotes Cell-Cycle Arrest, Induces Apoptosis, and Increases Immunogenicity of Merkel Cell Carcinoma Cells.
    J Invest Dermatol. 2021;141:903-912.
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  468. SRIVASTAVA RK, Khan J, Arumugam A, Muzaffar S, et al
    5'-CapDependent Translation as a Potent Therapeutic Target for Lethal Human Squamous Cell Carcinoma.
    J Invest Dermatol. 2021;141:742-753.
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  469. DELYON J, Porcher R, Battistella M, Meyer N, et al
    A Multicenter Phase II Study of Pazopanib in Patients with Unresectable Dermatofibrosarcoma Protuberans.
    J Invest Dermatol. 2021;141:761-769.
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  470. GILCHREST BA
    Actinic Keratoses: Reconciling the Biology of Field Cancerization with Treatment Paradigms.
    J Invest Dermatol. 2021;141:727-731.
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  471. YANG C, Ruiz-Rosado JD, Robledo-Avila FH, Li Z, et al
    Antibody-Mediated Protection against Staphylococcus aureus Dermonecrosis: Synergy of Toxin Neutralization and Neutrophil Recruitment.
    J Invest Dermatol. 2021;141:810-820.
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  472. BORNERT O, Hogervorst M, Nauroy P, Bischof J, et al
    QR-313, an Antisense Oligonucleotide, Shows Therapeutic Efficacy for Treatment of Dominant and Recessive Dystrophic Epidermolysis Bullosa: A Preclinical Study.
    J Invest Dermatol. 2021;141:883-893.
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  473. LUKAS D, Dietze-Schwonberg K, Kautz-Neu K, Lorenz B, et al
    Induction of Regulatory T Cells in Leishmania majorInfected BALB/c Mice Does Not Require Langerin+ Dendritic Cells.
    J Invest Dermatol. 2021;141:936-938.
    PubMed    


  474. HARDEN JL, Shih YH, Xu J, Li R, et al
    Paired Transcriptomic and Proteomic Analysis Implicates IL-1beta in the Pathogenesis of Papulopustular Rosacea Explants.
    J Invest Dermatol. 2021;141:800-809.
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  475. LE DUFF F, Bouaziz JD, Fontas E, Ticchioni M, et al
    Low-Dose IL-2 for Treating Moderate to Severe Alopecia Areata: A 52-Week Multicenter Prospective Placebo-Controlled Study Assessing its Impact on T Regulatory Cell and NK Cell Populations.
    J Invest Dermatol. 2021;141:933-936.
    PubMed    


  476. WHANG KA, Khanna R, Williams KA, Mahadevan V, et al
    Health-Related QOL and Economic Burden of Chronic Pruritus.
    J Invest Dermatol. 2021;141:754-760.
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  477. DU-HARPUR X, Arthurs C, Ganier C, Woolf R, et al
    Clinically Relevant Vulnerabilities of Deep Machine Learning Systems for Skin Cancer Diagnosis.
    J Invest Dermatol. 2021;141:916-920.
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  478. SANNA M, Li X, Visconti A, Freidin MB, et al
    Looking for Sunshine: Genetic Predisposition to Sun Seeking in 265,000 Individuals of European Ancestry.
    J Invest Dermatol. 2021;141:779-786.
    PubMed     Abstract available


  479. AHMAD S, Riddle AO, Sayed CJ
    Outcomes of Routine Diabetes Screening for Patients with Hidradenitis Suppurativa.
    J Invest Dermatol. 2021;141:927-930.
    PubMed    


  480. PENG W, Kwiek B, Yu C, Garbi N, et al
    Infiltration and Clustering of Major Histocompatibility Complex II(+) Antigen-Presenting Cells in the Skin of Patients with Atopic Dermatitis.
    J Invest Dermatol. 2021;141:939-942.
    PubMed    


  481. KIM HJ, Ahn HS, Kazmi SZ, Kang T, et al
    Familial Risk of Vitiligo among First-Degree Relatives and Spouses: A Population-Based Cohort Study in Korea.
    J Invest Dermatol. 2021;141:921-924.
    PubMed    


  482. CHEN J, Zhu Z, Li Q, Lin Y, et al
    Neutrophils Enhance Cutaneous Vascular Dilation and Permeability to Aggravate Psoriasis by Releasing Matrix Metallopeptidase 9.
    J Invest Dermatol. 2021;141:787-799.
    PubMed     Abstract available


  483. RAMOVS V, Krotenberg Garcia A, Kreft M, Sonnenberg A, et al
    Integrin alpha3beta1 Is a Key Regulator of Several Protumorigenic Pathways during Skin Carcinogenesis.
    J Invest Dermatol. 2021;141:732-741.
    PubMed     Abstract available


  484. PERSA OD, Koester J, Niessen CM
    Regulation of Cell Polarity and Tissue Architecture in Epidermal Aging and Cancer.
    J Invest Dermatol. 2021;141.
    PubMed     Abstract available


  485. RIZZA ERH, DiGiovanna JJ, Khan SG, Tamura D, et al
    Xeroderma Pigmentosum: A Model for Human Premature Aging.
    J Invest Dermatol. 2021;141.
    PubMed     Abstract available


    March 2021
  486. ZHAO Q, Almutairi M, Tailor A, Lister A, et al
    HLA Class II-restricted CD8+ T cells contribute to the promiscuous immune response in dapsone hypersensitive patients.
    J Invest Dermatol. 2021 Mar 30. pii: S0022-202X(21)01125.
    PubMed     Abstract available


  487. NADERI-AZAD S, Croitoru D, Khalili S, Eder L, et al
    Research Techniques Made Simple: Experimental Methodology for Imaging Mass Cytometry.
    J Invest Dermatol. 2021;141:467-473.
    PubMed     Abstract available


  488. QUAGLINO P, Fava P, Pileri A, Grandi V, et al
    Phenotypical Markers, Molecular Mutations, and Immune Microenvironment as Targets for New Treatments in Patients with Mycosis Fungoides and/or Sezary Syndrome.
    J Invest Dermatol. 2021;141:484-495.
    PubMed     Abstract available


  489. THOMAS J, Wang R, Batra R, Bohner A, et al
    CD23 Levels on B Cells Determine Long-Term Therapeutic Response in Patients with Atopic Eczema Treated with Selective IgE Immune Apheresis.
    J Invest Dermatol. 2021;141:681-685.
    PubMed    


  490. LI D, Peng H, Qu L, Sommar P, et al
    miR-19a/b and miR-20a Promote Wound Healing by Regulating the Inflammatory Response of Keratinocytes.
    J Invest Dermatol. 2021;141:659-671.
    PubMed     Abstract available


  491. HART PH, Norval M
    The Multiple Roles of Urocanic Acid in Health and Disease.
    J Invest Dermatol. 2021;141:496-502.
    PubMed     Abstract available


  492. VERMA D, Fekri SZ, Sigurdardottir G, Bivik Eding C, et al
    Enhanced Inflammasome Activity in Patients with Psoriasis Promotes Systemic Inflammation.
    J Invest Dermatol. 2021;141:586-595.
    PubMed     Abstract available


  493. BARE Y, Chan GK, Hayday T, McGrath JA, et al
    Slac2-b Coordinates Extracellular Vesicle Secretion to Regulate Keratinocyte Adhesion and Migration.
    J Invest Dermatol. 2021;141:523-532.
    PubMed     Abstract available


  494. KELEL M, Yang RB, Tsai TF, Liang PH, et al
    FUT8 Remodeling of EGFR Regulates Epidermal Keratinocyte Proliferation during Psoriasis Development.
    J Invest Dermatol. 2021;141:512-522.
    PubMed     Abstract available


  495. ZENG F, Chen H, Chen L, Mao J, et al
    An Autocrine Circuit of IL-33 in Keratinocytes Is Involved in the Progression of Psoriasis.
    J Invest Dermatol. 2021;141:596-606.
    PubMed     Abstract available


  496. SHIN JG, Leem S, Kim B, Kim Y, et al
    GWAS Analysis of 17,019 Korean Women Identifies the Variants Associated with Facial Pigmented Spots.
    J Invest Dermatol. 2021;141:555-562.
    PubMed     Abstract available


  497. LO YH, Li CS, Chen HL, Chiang CY, et al
    Galectin-8 Is Upregulated in Keratinocytes by IL-17A and Promotes Proliferation by Regulating Mitosis in Psoriasis.
    J Invest Dermatol. 2021;141:503-511.
    PubMed     Abstract available


  498. GOLDSTEIN NB, Steel A, Barbulescu CC, Koster MI, et al
    Melanocyte Precursors in the Hair Follicle Bulge of Repigmented Vitiligo Skin Are Controlled by RHO-GTPase, KCTD10, and CTNNB1 Signaling.
    J Invest Dermatol. 2021;141:638-647.
    PubMed     Abstract available


  499. L'HERONDELLE K, Pierre O, Fouyet S, Leschiera R, et al
    PAR2, Keratinocytes, and Cathepsin S Mediate the Sensory Effects of Ciguatoxins Responsible for Ciguatera Poisoning.
    J Invest Dermatol. 2021;141:648-658.
    PubMed     Abstract available


  500. STARK MS, Tell-Marti G, Martins da Silva V, Martinez-Barrios E, et al
    The Distinctive Genomic Landscape of Giant Congenital Melanocytic Nevi.
    J Invest Dermatol. 2021;141:692-695.
    PubMed    


  501. LIU K, Luo J, Ma T, Fang M, et al
    Germline Mutation of PLCD1 Contributes to Human Multiple Pilomatricomas through Protein Kinase D/Extracellular Signal-Regulated Kinase1/2 Cascade and TRPV6.
    J Invest Dermatol. 2021;141:533-544.
    PubMed     Abstract available


  502. ZHONG W, Hu L, Cao X, Zhao J, et al
    GenotypePhenotype Correlation of TRPV3-Related Olmsted Syndrome.
    J Invest Dermatol. 2021;141:545-554.
    PubMed     Abstract available


  503. ARONOVICH A, Moyal L, Gorovitz B, Amitay-Laish I, et al
    Cancer-Associated Fibroblasts in Mycosis Fungoides Promote Tumor Cell Migration and Drug Resistance through CXCL12/CXCR4.
    J Invest Dermatol. 2021;141:619-627.
    PubMed     Abstract available


  504. OKTEM A, Horzum U, Ertop P, Kundakci N, et al
    Clinical Relevance of Polymorphonuclear Myeloid-Derived Suppressor Cells in Autoimmune-Blistering Disorders Pemphigus Vulgaris and Bullous Pemphigoid.
    J Invest Dermatol. 2021;141:672-675.
    PubMed    


  505. GAO Y, Liu F, Sun J, Wen Y, et al
    Differential SATB1 Expression Reveals Heterogeneity of Cutaneous T-Cell Lymphoma.
    J Invest Dermatol. 2021;141:607-618.
    PubMed     Abstract available


  506. SHTESSEL M, Limjunyawong N, Oliver ET, Chichester K, et al
    MRGPRX2 Activation Causes Increased Skin Reactivity in Patients with Chronic Spontaneous Urticaria.
    J Invest Dermatol. 2021;141:678-681.
    PubMed    


  507. NOVAIS FO, Nguyen BT, Scott P
    Granzyme B Inhibition by Tofacitinib Blocks the Pathology Induced by CD8 T Cells in Cutaneous Leishmaniasis.
    J Invest Dermatol. 2021;141:575-585.
    PubMed     Abstract available


  508. JIANG M, Fang H, Dang E, Zhang J, et al
    Small Extracellular Vesicles Containing miR-381-3p from Keratinocytes Promote T Helper Type 1 and T Helper Type 17 Polarization in Psoriasis.
    J Invest Dermatol. 2021;141:563-574.
    PubMed     Abstract available


    February 2021
  509. BERNA R, Mitra N, Lou C, Wan J, et al
    TSLP and IL-7R Variants Are Associated with Persistent Atopic Dermatitis.
    J Invest Dermatol. 2021;141:446-450.
    PubMed    


  510. FEIZPOUR A, Marstrand T, Bastholm L, Eirefelt S, et al
    Label-Free Quantification of Pharmacokinetics in Skin with Stimulated Raman Scattering Microscopy and Deep Learning.
    J Invest Dermatol. 2021;141:395-403.
    PubMed     Abstract available


  511. JACKSON WD, Gulino A, Fossati-Jimack L, Castro Seoane R, et al
    C3 Drives Inflammatory Skin Carcinogenesis Independently of C5.
    J Invest Dermatol. 2021;141:404-414.
    PubMed     Abstract available


  512. DIETZE-SCHWONBERG K, Lorenz B, Hartmann AK, Stassen M, et al
    Mast Cell Deficiency Protects Susceptible BALB/c Mice from Progressive Murine Cutaneous Leishmaniasis.
    J Invest Dermatol. 2021;141:450-453.
    PubMed    


  513. HAO L, Park J, Jang HY, Bae EJ, et al
    Inhibiting Protein Kinase Activity of Pyruvate Kinase M2 by SIRT2 Deacetylase Attenuates Psoriasis.
    J Invest Dermatol. 2021;141:355-363.
    PubMed     Abstract available


  514. CLAUDER AK, Kordowski A, Bartsch YC, Kohl G, et al
    IgG Fc N-Glycosylation Translates MHCII Haplotype into Autoimmune Skin Disease.
    J Invest Dermatol. 2021;141:285-294.
    PubMed     Abstract available


  515. ZHENG Q, Capell BC, Parekh V, O'Day C, et al
    Whole-Exome and Transcriptome Analysis of UV-Exposed Epidermis and Carcinoma In Situ Reveals Early Drivers of Carcinogenesis.
    J Invest Dermatol. 2021;141:295-307.
    PubMed     Abstract available


  516. KOGUCHI-YOSHIOKA H, Watanabe R, Matsumura Y, Okiyama N, et al
    The Possible Linkage of Granzyme B-Producing Skin T Cells with the Disease Prognosis of Alopecia Areata.
    J Invest Dermatol. 2021;141:427-429.
    PubMed    


  517. GARSHICK MS, Baumer Y, Dey AK, Grattan R, et al
    Characterization of PCSK9 in the Blood and Skin of Psoriasis.
    J Invest Dermatol. 2021;141:308-315.
    PubMed     Abstract available


  518. WU CH, Yang CY, Wang L, Gao HX, et al
    Cutaneous T-Cell Lymphoma PDX Drug Screening Platform Identifies Cooperation between Inhibitions of PI3Kalpha/delta and HDAC.
    J Invest Dermatol. 2021;141:364-373.
    PubMed     Abstract available


  519. MIRANDA E, Roberts J, Novick S, Lapointe JM, et al
    Immunohistochemical Characterization of the IL-13:IL-4 Receptor alpha Axis in the Skin of Adult Patients with Moderate to Severe Atopic Dermatitis and Healthy Controls.
    J Invest Dermatol. 2021;141:440-443.
    PubMed    


    January 2021
  520. STONE RC, Aviv A, Paus R
    Telomere Dynamics and Telomerase in the Biology of Hair Follicles and their Stem Cells as a Model for Aging Research.
    J Invest Dermatol. 2021 Jan 25. pii: S0022-202X(20)32399.
    PubMed     Abstract available


    November 2020
  521. SAITO A, Ichimura Y, Kubota N, Tanaka R, et al
    Interferon-gamma-stimulated apoptotic keratinocytes promote sclerodermatous changes in chronic graft-versus-host disease.
    J Invest Dermatol. 2020 Nov 23. pii: S0022-202X(20)32290.
    PubMed     Abstract available


  522. CASTILLO-GONZALEZ R, Cibrian D, Fernandez-Gallego N, Ramirez-Huesca M, et al
    Galectin-1 expression in CD8(+) T lymphocytes controls inflammation in contact hypersensitivity.
    J Invest Dermatol. 2020 Nov 9. pii: S0022-202X(20)32281.
    PubMed     Abstract available


  523. WILKIE H, Janssen E, Leyva-Castillo JM, Geha RS, et al
    DOCK8 expression in Treg cells maintains their stability and limits contact hypersensitivity.
    J Invest Dermatol. 2020 Nov 7. pii: S0022-202X(20)32273.
    PubMed     Abstract available


    October 2020
  524. KUBOTA N, Saito A, Tanaka R, Nakamura Y, et al
    Langerhans cells suppress CD8(+) T cells in situ during mucocutaneous acute graft-versus host disease.
    J Invest Dermatol. 2020 Oct 19. pii: S0022-202X(20)32170.
    PubMed     Abstract available


    September 2020
  525. OLSEN CM, Pandeya N, Dusingize JC, Thompson BS, et al
    Can people correctly assess their future risk of melanoma?
    J Invest Dermatol. 2020 Sep 11. pii: S0022-202X(20)31964.
    PubMed    


  526. ZHANG C, Smalley I, Emmons MF, Sharma R, et al
    Non-canonical EphA2 signaling is a driver of tumor-endothelial cell interactions and metastatic dissemination in BRAF inhibitor resistant melanoma.
    J Invest Dermatol. 2020 Sep 2. pii: S0022-202X(20)32047.
    PubMed     Abstract available


    August 2020
  527. SWAMINATHAN K, Campbell A, Papalazarou V, Jaber-Hijazi F, et al
    The RAC1 target NCKAP1 plays a crucial role in progression of BRAF/PTEN -driven melanoma in mice.
    J Invest Dermatol. 2020 Aug 7. pii: S0022-202X(20)31956.
    PubMed     Abstract available


    July 2020
  528. LE K, Matar H, Gupta M
    Bromodomain epigenetic protein promotes metastatic potential in melanoma cells via increased invasiveness and decreased macrophage-mediated phagocytosis.
    J Invest Dermatol. 2020 Jul 6. pii: S0022-202X(20)31733.
    PubMed    


  529. XIONG H, Jiang M, Shao F, Ye H, et al
    Risk and association of HLA alleles with methimazole-induced cutaneous adverse reactions in Chinese Han population.
    J Invest Dermatol. 2020 Jul 1. pii: S0022-202X(20)31824.
    PubMed    


    June 2020
  530. WANG P, Li Y, Ma Y, Zhang X, et al
    Comprehensive investigation into the role of ubiquitin conjugating enzyme E2S (UBE2S) in melanoma development.
    J Invest Dermatol. 2020 Jun 27. pii: S0022-202X(20)31729.
    PubMed     Abstract available


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