: The AMEDEO Literature Guide

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Articles published in J Invest Dermatol
Retrieve available abstracts of 530 articles:
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February 2023

COULOMBE PA, Orosco A
Inhibiting EGFR Signaling Holds Promise for Treating Palmoplantar Keratodermas.
J Invest Dermatol. 2023;143:185-188.
PubMed

SAPAO P, Roberson EDO, Shi B, Assassi S, et al
Reduced SPAG17 Expression in Systemic Sclerosis Triggers Myofibroblast Transition and Drives Fibrosis.
J Invest Dermatol. 2023;143:284-293.
PubMed Abstract available

MEYER JM, Vavrova K, Radner FPW, Schneider H, et al
ALOX12B and PNPLA1 Have Distinct Roles in Epidermal Lipid Lamellar Organization.
J Invest Dermatol. 2023;143:332-335.
PubMed

BASSET J, Marchal L, Hovnanian A
EGFR Signaling Is Overactive in Pachyonychia Congenita: Effective Treatment with Oral Erlotinib.
J Invest Dermatol. 2023;143:294-304.
PubMed Abstract available

MACCHIARELLA G, Cornacchione V, Cojean C, Riker J, et al
Disease Association of Antiâ€’Carboxyethyl Lysine Autoantibodies in Hidradenitis Suppurativa.
J Invest Dermatol. 2023;143:273-283.
PubMed Abstract available

HOLM NIELSEN S, Groen SS, Yao Y, Jorgensen AR, et al
Biomarkers of Tissue Turnover and Systemic Inflammation Are Associated with Disease Severity and Activity in Patients with Hidradenitis Suppurativa.
J Invest Dermatol. 2023;143:328-331.
PubMed

HUDEMANN C, Exner Y, Pollmann R, Schneider K, et al
IgG against the Membrane-Proximal Portion of the Desmoglein 3 Ectodomain Induces Loss of Keratinocyte Adhesion, a Hallmark in Pemphigus Vulgaris.
J Invest Dermatol. 2023;143:254-263.
PubMed Abstract available

RASSEK K, Izykowska K, Zurawek M, Nowicka K, et al
TMEM244 Gene Expression as a Potential Blood Diagnostic Marker Distinguishing Sezary Syndrome from Mycosis Fungoides and Benign Erythroderma.
J Invest Dermatol. 2023;143:344-347.
PubMed

FANG H, Xue K, Cao T, Li Q, et al
CXCL12/CXCR4 Axis Drives the Chemotaxis and Differentiation of B Cells in Bullous Pemphigoid.
J Invest Dermatol. 2023;143:197-208.
PubMed Abstract available

January 2023

GUICHENEY M, Ducharme O, Caumont C, Gerard E, et al
Assessment of liquid biopsy in primary cutaneous diffuse large B-Cell lymphoma- leg type.
J Invest Dermatol. 2023 Jan 21:S0022-202X(23)00020.
PubMed

SCHMIDT AD, Miciano C, Zheng Q, Mathyer ME, et al
Involucrin modulates vitamin D receptor activity in the epidermis.
J Invest Dermatol. 2023 Jan 12:S0022-202X(22)02903.
PubMed Abstract available

DELLA BELLA C, Corra A, Mantengoli E, Galano A, et al
Skin IL-17A and IFN-gamma production correlate with disease severity in patients with psoriasis and streptococcal infection.
J Invest Dermatol. 2023 Jan 12:S0022-202X(22)02899.
PubMed Abstract available

AGARWAL A, Orlow SJ
Skin in the Game: An Analysis of Venture Capital Investment in Dermatology from 2002 to 2021.
J Invest Dermatol. 2023 Jan 11:S0022-202X(22)02767.
PubMed

NEMETH T, Balogh L, Kaposztas E, Szilveszter KP, et al
Neutrophil-specific Syk expression is crucial for skin disease in experimental epidermolysis bullosa acquisita.
J Invest Dermatol. 2023 Jan 11:S0022-202X(23)00010.
PubMed Abstract available

KIM RW, An Y, Zukley L, Ferrucci L, et al
Skin Barrier Function and Cognition Among Older Adults.
J Invest Dermatol. 2023 Jan 11:S0022-202X(22)02897.
PubMed

PADHI A, Rekha RS, Benrejdal L, Grundeken ME, et al
Baricitinib blocks cytokine mediated downregulation of PAD1 in human keratinocytes: a possible molecular link to the effects of JAK-inhibitors in atopic dermatitis.
J Invest Dermatol. 2023 Jan 11:S0022-202X(23)00001.
PubMed

LUO L, Pasquali L, Srivastava A, Freisenhausen JC, et al
The long non-coding RNA LINC00958 is induced in psoriasis epidermis and modulates epidermal proliferation.
J Invest Dermatol. 2023 Jan 11:S0022-202X(22)02905.
PubMed Abstract available

KANG T, Zhang C, Lei H, Luo R, et al
NPTX2 Promotes EMT in Cutaneous Squamous Cell Carcinoma via Mettl3-Mediated m(6)A Methylation of Snail.
J Invest Dermatol. 2023 Jan 10:S0022-202X(23)00009.
PubMed Abstract available

MENG Q, Bai M, Guo M, Li Z, et al
Inhibition of serum and glucocorticoid-regulated protein kinase-1 aggravates imiquimod-induced psoriatic dermatitis and enhances proinflammatory cytokine expression via the NF-kappaB pathway.
J Invest Dermatol. 2023 Jan 6:S0022-202X(23)00007.
PubMed Abstract available

GROLLEAU C, Calugareanu A, Demouche S, Nosbaum A, et al
IL-4/IL-13 inhibitors for atopic dermatitis induce psoriatic rash transcriptionally close to pustular psoriasis.
J Invest Dermatol. 2023 Jan 4:S0022-202X(22)02817.
PubMed Abstract available

LIU W, Xu R, Wang F
Recent Advances of Basophils in Pruritic Skin Diseases.
J Invest Dermatol. 2023 Jan 4:S0022-202X(22)02889.
PubMed Abstract available

ZHANG L, Qiu L, Wu J, Qi Y, et al
GWAS of Chronic Spontaneous Urticaria Reveals Genetic Overlap with Autoimmune Diseases, Not Atopic Diseases.
J Invest Dermatol. 2023;143:67-77.
PubMed Abstract available

WALL D, Rees H, Bokhari L, Meah N, et al
Signposts to the Promised Land in Alopecia Areata.
J Invest Dermatol. 2023;143:9-10.
PubMed

DE LOGU F, Maglie R, Titiz M, Poli G, et al
miRNA-203b-3p Induces Acute and Chronic Pruritus through 5-HTR2B and TRPV4.
J Invest Dermatol. 2023;143:142-153.
PubMed Abstract available

AHMED MM, Rivas HG, Frost TC, DeCaprio JA, et al
Distinct Radiation Responses in Virus-Positive and Virus-Negative Merkel Cell Carcinoma.
J Invest Dermatol. 2023;143:166-169.
PubMed

OLIVEIRA CB, Byrd AS, Okoye GA, Kaplan MJ, et al
Neutralizing Antiâ€’DNase 1 and â€’DNase 1L3 Antibodies Impair Neutrophil Extracellular Traps Degradation in Hidradenitis Suppurativa.
J Invest Dermatol. 2023;143:57-66.
PubMed Abstract available

RAZA R, Chhabra G, Bilal M, Ndiaye MA, et al
A Homozygous Missense Variant in K25 Underlying Overlapping Phenotype with Woolly Hair and Dental Anomalies.
J Invest Dermatol. 2023;143:173-176.
PubMed

CICHON MA, Elbe-Burger A
Epidermal/Dermal Separation Techniques and Analysis of Cell Populations in Human Skin Sheets.
J Invest Dermatol. 2023;143:11-17.
PubMed Abstract available

December 2022

HUFBAUER M, Rattay S, Hagen C, Quaas A, et al
Poly(I:C) treatment prevents skin tumor formation in the preclinical HPV8 transgenic mouse model.
J Invest Dermatol. 2022 Dec 27:S0022-202X(22)02900.
PubMed Abstract available

NANRI Y, Nunomura S, Honda Y, Takedomi H, et al
A positive loop formed by SOX11 and periostin upregulates TGF-beta signals leading to skin fibrosis.
J Invest Dermatol. 2022 Dec 27:S0022-202X(22)02902.
PubMed Abstract available

OLSSON-BROWN A, Yip V, Ogiji ED, Jolly C, et al
TNF-alpha mediated keratinocyte expression and release of matrix metalloproteinase 9: putative mechanism of pathogenesis in Stevens-Johnson syndrome/ toxic epidermal necrolysis.
J Invest Dermatol. 2022 Dec 26:S0022-202X(22)02898.
PubMed Abstract available

POLUBOTHU S, Bender N, Muthiah S, Zecchin D, et al
PTPN11 mosaicism causes a spectrum of pigmentary and vascular neurocutaneous disorders and predisposes to melanoma.
J Invest Dermatol. 2022 Dec 22:S0022-202X(22)02891.
PubMed Abstract available

LADA G, Chinoy H, Talbot PS, Warren RB, et al
The Relationship of Depression and Systemic Inflammation in Psoriasis; Findings from the UK Biobank.
J Invest Dermatol. 2022 Dec 22:S0022-202X(22)02894.
PubMed

YI-PIN LEE C, Carissimo G, Teo TH, Ming Tong SJ, et al
CD8+ T-cells trigger auricular dermatitis and blepharitis in mice post-Zika virus infection in the absence of CD4+ T-cells.
J Invest Dermatol. 2022 Dec 22:S0022-202X(22)02893.
PubMed Abstract available

CHIMBETETE T, Buck C, Choshi P, Selim R, et al
HIV-Associated Immune Dysregulation in the Skin: A Crucible for Exaggerated Inflammation and Hypersensitivity.
J Invest Dermatol. 2022 Dec 20:S0022-202X(22)02769.
PubMed Abstract available

AFACH S, Le Cleach L, Sbidian E
Placebo response in moderate-to-severe psoriasis: prevalence meta-analysis of randomised controlled trials.
J Invest Dermatol. 2022 Dec 20:S0022-202X(22)02892.
PubMed

GUPTA I, Shankrit S, Narta K, Ghazi M, et al
Whole exome-sequencing of vitiligo lesions indicate lower burden of somatic variations: implications in risk for non-melanoma skin cancers.
J Invest Dermatol. 2022 Dec 16:S0022-202X(22)02884.
PubMed

TSAO CH, Hsieh WC, Lin FJ, Yang RY, et al
The Critical Role of Galectin-12 in Modulating Lipid Metabolism in Sebaceous Glands.
J Invest Dermatol. 2022 Dec 16:S0022-202X(22)02842.
PubMed Abstract available

RANA I, Kataria S, Tan TL, Hajam EY, et al
MINDIN (SPONDIN-2) IS ESSENTIAL FOR CUTANEOUS FIBROGENESIS IN A MOUSE MODEL OF SYSTEMIC SCLEROSIS.
J Invest Dermatol. 2022 Dec 14:S0022-202X(22)02695.
PubMed Abstract available

JAYASINGHE D, Betz-Stablein B, Stark MS, Soyer HP, et al
Spatial Randomness in the distribution of acquired melanocytic naevi of the back in a population-based sample.
J Invest Dermatol. 2022 Dec 13:S0022-202X(22)02843.
PubMed

SUN J, Zhou J, Zhou J, Xu W, et al
FGF4 promotes skin wound repair through p38 MAPK and GSK3beta-mediated stabilization of Slug.
J Invest Dermatol. 2022 Dec 12:S0022-202X(22)02845.
PubMed Abstract available

KARMON M, Kopel E, Barzilai A, Geva P, et al
Altered RNA editing in Atopic Dermatitis highlights the role of dsRNA for immune surveillance.
J Invest Dermatol. 2022 Dec 8:S0022-202X(22)02837.
PubMed Abstract available

CHEN XY, Xu F, Chen JQ, Landeck L, et al
UBE2L3 Reduces TRIM21 Expression and Interleukin-1beta Secretion in Epidermal Keratinocytes and Improves Psoriasis-like Skin.
J Invest Dermatol. 2022 Dec 8:S0022-202X(22)02819.
PubMed Abstract available

GONZALEZ JR, Celli A, Weckel A, Dhariwala MO, et al
Filaggrin deficiency in mice alters the early life CD4(+) T cell response to skin commensal bacteria.
J Invest Dermatol. 2022 Dec 7:S0022-202X(22)02822.
PubMed Abstract available

HU T, Todberg T, Ewald DA, Hoof I, et al
Assessment of Spatial and Temporal Variation in the Skin Transcriptome of Atopic Dermatitis by Use of 1.5 mm Mini Punch Biopsies.
J Invest Dermatol. 2022 Dec 7:S0022-202X(22)02657.
PubMed Abstract available

BORGOGNA C, Martuscelli L, Olivero C, Lo Cigno I, et al
Enhanced Spontaneous Skin Tumorigenesis and Aberrant Inflammatory Response to UVB Exposure in Immunosuppressed HPV8 Transgenic Mice.
J Invest Dermatol. 2022 Dec 5:S0022-202X(22)02829.
PubMed Abstract available

MORISAKA H, Takaishi M, Akira S, Sano S, et al
Keratinocyte Regnase-1, a down-regulator of skin inflammation, contributes to protection against tumor promotion by limiting COX-2 expression.
J Invest Dermatol. 2022 Dec 2:S0022-202X(22)02827.
PubMed Abstract available

PLAZYO O, Gudjonsson JE
Hitting the Bullseye in Autoimmunity: Targeting Biologics through Tethering: Examining a Therapeutic Potential for Vitiligo and Beyond.
J Invest Dermatol. 2022;142:3133-3135.
PubMed

DUAN J, Grando C, Liu S, Chernyavsky A, et al
The M3 Muscarinic Acetylcholine Receptor Promotes Epidermal Differentiation.
J Invest Dermatol. 2022;142:3211-3221.
PubMed Abstract available

JIANG M, Wang J, Shen Y, Zhu J, et al
Ribosomal S6 Protein Kinase 2 Aggravates the Process of Systemic Scleroderma.
J Invest Dermatol. 2022;142:3175-3183.
PubMed Abstract available

PANDYA AG, Harris JE, Lebwohl M, Hamzavi IH, et al
Addition of Narrow-Band UVB Phototherapy to Ruxolitinib Cream in Patients With Vitiligo.
J Invest Dermatol. 2022;142:3352-3355.
PubMed

HSUEH YC, Wang Y, Riding RL, Catalano DE, et al
A Keratinocyte-Tethered Biologic Enables Location-Precise Treatment in Mouse Vitiligo.
J Invest Dermatol. 2022;142:3294-3303.
PubMed Abstract available

ZHAO L, Hsiao T, Stonesifer C, Daniels J, et al
The Robust Tumoricidal Effects of Combined BET/HDAC Inhibition in Cutaneous T-Cell Lymphoma Can Be Reproduced by DeltaNp73 Depletion.
J Invest Dermatol. 2022;142:3253-3261.
PubMed Abstract available

BOCH K, Sharma A, Folberth J, Zillikens D, et al
Distinct Metabolite Profile in Pemphigus Vulgaris.
J Invest Dermatol. 2022;142:3327-3331.
PubMed

RIETSCHER K, Jahnke HG, Rubsam M, Lin EW, et al
Kinase Inhibition by PKC412 Prevents Epithelial Sheet Damage in Autosomal Dominant Epidermolysis Bullosa Simplex through Keratin and Cell Contact Stabilization.
J Invest Dermatol. 2022;142:3282-3293.
PubMed Abstract available

HEIM X, Bermudez J, Joshkon A, Kaspi E, et al
CD146 at the Interface between Oxidative Stress and the Wnt Signaling Pathway in Systemic Sclerosis.
J Invest Dermatol. 2022;142:3200-3210.
PubMed Abstract available

November 2022

LIU X, Li L, Jiang J, Ge W, et al
The key role of CB1R in the sensory neurons to regulate psoriasiform skin inflammation and pruritus.
J Invest Dermatol. 2022 Nov 18:S0022-202X(22)02770.
PubMed Abstract available

DONG B, Simonson L, Vold S, Oldham E, et al
Frizzled 6 promotes melanoma cell invasion but not proliferation by regulating canonical Wnt signaling and EMT.
J Invest Dermatol. 2022 Nov 8. pii: S0022-202X(22)02660.
PubMed Abstract available

KIM Y, Yin J, Le Breton S, Jorgenson E, et al
Genetically Predicted Serum Vitamin C Levels and Cutaneous Squamous Cell Carcinoma Risk.
J Invest Dermatol. 2022 Nov 4. pii: S0022-202X(22)02659.
PubMed

ABDELAZEEM B, Abbas KS, Shehata J, Alfaar AS, et al
Increased Risk of Subsequent Skin Melanoma in Patients with Retinoblastoma: SEER-Based Results.
J Invest Dermatol. 2022;142:3123-3125.
PubMed

PRIYA S, Kirschner LS
Abnormal Fibroblasts Drive Pigmentary Skin Lesions in a Mouse Model of Carney Complex.
J Invest Dermatol. 2022;142:2850-2852.
PubMed

RAMCKE T, Bolduan V, Vicari E, Yilmaz K, et al
Anti-BP230 Only Bullous Pemphigoid Constitutes a Distinct Disease Subgroup with Characteristic Serological and Clinical Features.
J Invest Dermatol. 2022;142:3110-3113.
PubMed

FANG X, Li M, He C, Liu Q, et al
Plasma-Derived Exosomes in Chronic Spontaneous Urticaria Induce the Production of Mediators by Human Mast Cells.
J Invest Dermatol. 2022;142:2998-3008.
PubMed Abstract available

ROY S, Alkanfari I, Chaki S, Ali H, et al
Role of MrgprB2 in Rosacea-Like Inflammation in Mice: Modulation by beta-Arrestin 2.
J Invest Dermatol. 2022;142:2988-2997.
PubMed Abstract available

SCHLEMEYER T, Ohnezeit D, Virdi S, Korner C, et al
Merkel Cell Carcinoma and Immune Evasion: Merkel Cell Polyomavirus Small T-AntigenInduced Surface Changes Can Be Reverted by Therapeutic Intervention.
J Invest Dermatol. 2022;142:3071-3081.
PubMed Abstract available

SHAH P, Polsky D, Shao Y, Stein J, et al
Patient- and County-Level Factors Associated with Late-Stage Merkel Cell Carcinoma at Diagnosis.
J Invest Dermatol. 2022;142:3113-3117.
PubMed

PICOZZA M, Cristofoletti C, Bresin A, Fioretti M, et al
Genetically Driven CD39 Expression Affects Sezary Cell Viability and IL-2 Production and Detects Two Patient Subsets with Distinct Prognosis.
J Invest Dermatol. 2022;142:3009-3019.
PubMed Abstract available

HARMS PW, Chan MP, Bresler SC, Andea AA, et al
Comment on "An Epidemiologic Analysis of Melanoma Overdiagnosis in the United States, 1975-2017".
J Invest Dermatol. 2022;142:3120-3122.
PubMed

October 2022

CHEN C, Tang Y, Zhu X, Yang J, et al
P311 promotes IL-4R-mediated M2 polarization of macrophages to enhance angiogenesis for efficient skin wound healing.
J Invest Dermatol. 2022 Oct 26. pii: S0022-202X(22)02661.
PubMed Abstract available

MICALI G, Verzi AE, Musumeci ML, Nardone B, et al
NON-INVASIVE EVALUATION OF DIAMETER AND DENSITY OF DERMAL PAPILLAE IN PSORIATIC AND HEALTHY SKIN USING REFLECTANCE CONFOCAL MICROSCOPY: AN INTRAPATIENT CONTROLLED STUDY AND A REVIEW.
J Invest Dermatol. 2022 Oct 20. pii: S0022-202X(22)02656.
PubMed

LUU YT, Luo Q, Horner MJ, Shiels M, et al
Risk of nonkeratinocyte skin cancers in people living with HIV during the era of antiretroviral therapy.
J Invest Dermatol. 2022 Oct 7. pii: S0022-202X(22)01942.
PubMed Abstract available

CAI KQ, Shellhamer C, Akiyama T, Jensen LE, et al
Pellino1 restricts herpes simplex virus infections in the epidermis and dissemination to sebaceous glands.
J Invest Dermatol. 2022 Oct 7. pii: S0022-202X(22)01941.
PubMed

PINEIDER J, Eckert KM, McDonald JG, Harris-Tryon T, et al
Cutaneous hormone production is distinct between anatomical sites and between males and females.
J Invest Dermatol. 2022 Oct 5. pii: S0022-202X(22)02583.
PubMed Abstract available

DIVINCENZO MJ, Schwarz E, Ren C, Barricklow Z, et al
Expression patterns of microRNAs and associated target genes in ulcerated primary cutaneous melanoma.
J Invest Dermatol. 2022 Oct 3. pii: S0022-202X(22)02640.
PubMed Abstract available

WITTMANN M, Staubach P, McGonagle D
Toward Cannabinoid Use for Refractory Cutaneous Dermatomyositis.
J Invest Dermatol. 2022;142:2556-2557.
PubMed

COUTIER J, Bonnette M, Martineau S, Mercadier A, et al
Human-Induced Pluripotent Stem CellDerived Keratinocytes, a Useful Model to Identify and Explore the Pathological Phenotype of Epidermolysis Bullosa Simplex.
J Invest Dermatol. 2022;142:2695-2705.
PubMed Abstract available

FANG J, Ouyang M, Qu Y, Wang M, et al
Advanced Glycation End Products Promote Melanogenesis by Activating NLRP3 Inflammasome in Human Dermal Fibroblasts.
J Invest Dermatol. 2022;142:2591-2602.
PubMed Abstract available

YANG F, Jiang X, Zhu Y, Lee M, et al
Biallelic Variants in Lanosterol Synthase (LSS) Cause Palmoplantar Keratoderma-Congenital Alopecia Syndrome Type 2.
J Invest Dermatol. 2022;142:2687-2694.
PubMed Abstract available

YEO H, Ahn SS, Jung E, Lim Y, et al
Transcription Factor EGR1 Regulates the Expression of the Clock Gene PER2 under IL-4 Stimulation in Human Keratinocytes.
J Invest Dermatol. 2022;142:2677-2686.
PubMed Abstract available

BRIDGEWOOD C, Wittmann M, Macleod T, Watad A, et al
T Helper 2 IL-4/IL-13 Dual Blockade with Dupilumab Is Linked to Some Emergent T Helper 17Type Diseases, Including Seronegative Arthritis and Enthesitis/Enthesopathy, but Not to Humoral Autoimmune Diseases.
J Invest Dermatol. 2022;142:2660-2667.
PubMed Abstract available

GARTIN AK, Frost TC, Cushman CH, Leeper BA, et al
Merkel Cell Carcinoma Sensitivity to EZH2 Inhibition Is Mediated by SIX1 Derepression.
J Invest Dermatol. 2022;142:2783-2792.
PubMed Abstract available

SENNA M, Ko J, Glashofer M, Walker C, et al
Predictors of QOL in Patients with Alopecia Areata.
J Invest Dermatol. 2022;142:2646-2650.
PubMed Abstract available

SEILER DL, Kleingarn M, Kahler KH, Gruner C, et al
C5aR2 Deficiency Ameliorates Inflammation in Murine Epidermolysis Bullosa Acquisita by Regulating Fcgamma Receptor Expression on Neutrophils.
J Invest Dermatol. 2022;142:2715-2723.
PubMed Abstract available

SHANG W, Tan AYQ, van Steensel MAM, Lim X, et al
Aberrant Wnt Signaling Induces Comedo-Like Changes in the Murine Upper Hair Follicle.
J Invest Dermatol. 2022;142:2603-2612.
PubMed Abstract available

September 2022

SHI B, Tsou PS, Ma F, Mariani MP, et al
Senescent cells accumulate in systemic sclerosis skin.
J Invest Dermatol. 2022 Sep 30. pii: S0022-202X(22)02637.
PubMed

KIM J, He Y, Tormen S, Kleindienst P, et al
The p300/CBP inhibitor A485 normalizes psoriatic fibroblast gene expression in vitro and reduces psoriasis-like skin inflammation in vivo.
J Invest Dermatol. 2022 Sep 26. pii: S0022-202X(22)01937.
PubMed Abstract available

SILVA-VILCHES C, Bolduan V, Alabdullah M, Steinbrink K, et al
Topical application of adenosine A2-type receptor agonists prevents contact hypersensitivity reactions in mice by affecting skin dendritic cells.
J Invest Dermatol. 2022 Sep 26. pii: S0022-202X(22)01908.
PubMed Abstract available

CHAKRABORTY A, Perez M, Carroll JD, Antonopoulos A, et al
Hypoxia controls the glycome signature and galectin-8 - ligand axis to promote pro-tumorigenic properties of metastatic melanoma.
J Invest Dermatol. 2022 Sep 26. pii: S0022-202X(22)01931.
PubMed Abstract available

ZHANG Y, LeWitt TM, Louissaint A Jr, Guitart J, et al
Disease-Defining Molecular Features of Primary Cutaneous B-Cell Lymphomas: Implications for Classification and Treatment.
J Invest Dermatol. 2022 Sep 24. pii: S0022-202X(22)01887.
PubMed Abstract available

WU H, Ke X, Huang W, Shi W, et al
Multi-Tissue Integrative Analysis Identifies Susceptibility Genes for Atopic Dermatitis.
J Invest Dermatol. 2022 Sep 22. pii: S0022-202X(22)01940.
PubMed Abstract available

GRANTHAM HJ, Hussain AB, Reynolds NJ
Serum S100A8/A9 May Act as Biomarker of Atherosclerosis Severity in Psoriasis.
J Invest Dermatol. 2022 Sep 16. pii: S0022-202X(22)01670.
PubMed

KREUGER IZM, Slieker RC, van Groningen T, van Doorn R, et al
Therapeutic Strategies for Targeting CDKN2A Loss in Melanoma.
J Invest Dermatol. 2022 Sep 16. pii: S0022-202X(22)01769.
PubMed Abstract available

YAN Y, Tian J, Wang Y, Li Y, et al
Transcriptomic heterogeneity of skin across different anatomic sites.
J Invest Dermatol. 2022 Sep 16. pii: S0022-202X(22)01932.
PubMed Abstract available

KOCH M, Kockmann T, Rodriguez E, Wehkamp U, et al
Quantitative proteomics identifies reduced NRF2 activity and mitochondrial dysfunction in Atopic Dermatitis.
J Invest Dermatol. 2022 Sep 12. pii: S0022-202X(22)01904.
PubMed Abstract available

PROCHAZKOVA-CARLOTTI M, Gros A, Richard E, Cherrier F, et al
Patient-derived xenograft and cell line models of human primary cutaneous diffuse large B cell lymphoma-leg type.
J Invest Dermatol. 2022 Sep 6. pii: S0022-202X(22)01896.
PubMed

AGELOPOULOS K, Renkhold L, Wiegmann H, Dugas M, et al
Transcriptomic, epigenomic and neuro-anatomic signatures differ in chronic prurigo, atopic dermatitis and brachioradial pruritus.
J Invest Dermatol. 2022 Sep 5. pii: S0022-202X(22)01895.
PubMed Abstract available

PARK JJ, Choate K
Assessing Cutaneous Mosaicism at the Molecular Level.
J Invest Dermatol. 2022;142:2306-2312.
PubMed Abstract available

DANESHJOU R
Toward Augmented Intelligence: The First Prospective, Randomized Clinical Trial Assessing Clinician and Artificial Intelligence Collaboration in Dermatology.
J Invest Dermatol. 2022;142:2301-2302.
PubMed Abstract available

VAN SANTEN S, Zoutman WH, de Masson A, Quint KD, et al
Tumor Clone Frequency Calculation Using High-Throughput Sequencing of the TCRbeta Gene in Patients with Folliculotropic Mycosis Fungoides.
J Invest Dermatol. 2022;142:2544-2546.
PubMed

RIEDL JA, Riddle M, Xia L, Eide C, et al
Interrogation of RDEB Epidermal Allografts after BMT Reveals Coexpression of Collagen VII and Keratin 15 with Proinflammatory Immune Cells and Fibroblasts.
J Invest Dermatol. 2022;142:2424-2434.
PubMed Abstract available

LASHERAS-OTERO I, Feliu I, Maillo A, Moreno H, et al
The regulators of peroxisomal acyl-carnitine shuttle CROT and CRAT promote metastasis in melanoma.
J Invest Dermatol. 2022 Sep 1. pii: S0022-202X(22)01890.
PubMed Abstract available

ZHU R, Yang H, Xue S, Fan Q, et al
Intervening GSK3 Signaling Attenuates Cutaneous Inflammation and Itch in Mice: Implication for Future Therapeutic Development.
J Invest Dermatol. 2022 Sep 1. pii: S0022-202X(22)01889.
PubMed

August 2022

TECHNER JM, Hooper MJ, Evans S, LeWitt TM, et al
Skin tape strip proteomics in mycosis fungoides identifies tumor-associated biomarkers.
J Invest Dermatol. 2022 Aug 30. pii: S0022-202X(22)01880.
PubMed

SHEA LK, Akhave NS, Sutton LA, Compton LA, et al
Combined Kdm6a and Trp53 deficiency drives the development of squamous cell skin cancer in mice.
J Invest Dermatol. 2022 Aug 30. pii: S0022-202X(22)01888.
PubMed Abstract available

DONOVAN M, Duke R, Simonetti L, Cavusoglu N, et al
N-glycans are stratum corneum biomarkers of aging skin.
J Invest Dermatol. 2022 Aug 30. pii: S0022-202X(22)01877.
PubMed

GARZA LA, Sheu M, Kim N, Tsai J, et al
Association of Early Clinical Response to Laser Rejuvenation of Photoaged Skin with Increased Lipid Metabolism and Restoration of Skin Barrier Function.
J Invest Dermatol. 2022 Aug 30. pii: S0022-202X(22)01878.
PubMed Abstract available

ZHANG J, He L, Wang Z, Shao S, et al
Decreasing growth differentiation factor 15 promotes inflammatory signals and neutrophil infiltration in psoriasis models.
J Invest Dermatol. 2022 Aug 29. pii: S0022-202X(22)01885.
PubMed Abstract available

SOLE C, Domingo S, Penzo E, Moline T, et al
Downregulation of miR-885-5p promotes NF-kappaB pathway activation and immune recruitment in Cutaneous Lupus Erythematosus.
J Invest Dermatol. 2022 Aug 29. pii: S0022-202X(22)01886.
PubMed Abstract available

JOUR G, Illa-Bochaca I, Ibrahim M, Donnelly D, et al
Genomic and transcriptomic analyses of NF1-mutant melanoma identify potential targeted approach for treatment.
J Invest Dermatol. 2022 Aug 18. pii: S0022-202X(22)01780.
PubMed Abstract available

KIM JH, Ahn S, Ghosh P, Rhee DK, et al
Immunization with a Pneumococcal pep27 Mutant Strain Alleviates Atopic Dermatitis by Upregulation of Regulatory T Cell Activity and Epithelial Barrier Function and Suppressing TSLP Expression.
J Invest Dermatol. 2022 Aug 18. pii: S0022-202X(22)01779.
PubMed Abstract available

TUCHAYI SM, Wang Y, Khodorova A, Pence IJ, et al
Cryoneurolysis with Injectable Ice Slurry Modulates Mechanical skin pain.
J Invest Dermatol. 2022 Aug 16. pii: S0022-202X(22)01773.
PubMed Abstract available

LINDGREN O, Le Menn G, Tuusa J, Chen JZ, et al
Absence of NC14A domain of collagen XVII/BP180 in mice results in IL-17-associated skin inflammation.
J Invest Dermatol. 2022 Aug 16. pii: S0022-202X(22)01777.
PubMed Abstract available

ALMOUGHRABIE S, Gallo RL
Interdependence of Sebaceous Lipids and the Microbiome in Atopic Dermatitis.
J Invest Dermatol. 2022 Aug 16. pii: S0022-202X(22)01679.
PubMed

MENGUY S, Prochazkova-Carlotti M, Azzi-Martin L, Ferte T, et al
Proliferative tumor infiltrating lymphocytes abundance within microenvironment impact clinical outcome in cutaneous B-cell lymphomas.
J Invest Dermatol. 2022 Aug 12. pii: S0022-202X(22)01771.
PubMed Abstract available

RISNES LF, Chlubnova M, Magistrelli E, Kemppainen E, et al
Phenotypic Analysis of Disease-Relevant T Cells In Dermatitis Herpetiformis.
J Invest Dermatol. 2022 Aug 9. pii: S0022-202X(22)01685.
PubMed

WANG CQ, Haxhinasto S, Garcet S, Kunjravia N, et al
Comparison of the Inflammatory Circuits in Psoriasis Vulgaris, Non-Pustular Palmoplantar Psoriasis, and Palmoplantar Pustular Psoriasis.
J Invest Dermatol. 2022 Aug 4. pii: S0022-202X(22)01684.
PubMed Abstract available

REIMER-TASCHENBRECKER A, Kunstner A, Hirose M, Hubner S, et al
Predominance of Staphylococcus Correlates with Wound Burden and Disease Activity in Dystrophic Epidermolysis Bullosa: A Prospective Case-Control Study.
J Invest Dermatol. 2022;142:2117-2127.
PubMed Abstract available

HUANG J, Ralph D, Boraldi F, Quaglino D, et al
Inhibition of the DNA Damage Response Attenuates Ectopic Calcification in Pseudoxanthoma Elasticum.
J Invest Dermatol. 2022;142:2140-2148.
PubMed Abstract available

KUAI L, Ru Y, Zhu QG, Yin SY, et al
Celastrol Attenuates Psoriasiform Inflammation by Targeting the IRF1/GSTM3 Axis.
J Invest Dermatol. 2022;142:2281-2285.
PubMed

CHANDRASEKHARAN UM, Kaur R, Harvey JE, Braley C, et al
TNFR2 Depletion Reduces Psoriatic Inflammation in Mice by Downregulating Specific Dendritic Cell Populations in Lymph Nodes and Inhibiting IL-23/IL-17 Pathways.
J Invest Dermatol. 2022;142:2159-2172.
PubMed Abstract available

DAI X, Muto J, Shiraishi K, Utsunomiya R, et al
TSLP Impairs Epidermal Barrier Integrity by Stimulating the Formation of Nuclear IL-33/Phosphorylated STAT3 Complex in Human Keratinocytes.
J Invest Dermatol. 2022;142:2100-2108.
PubMed Abstract available

DENG Z, Chen M, Liu F, Wang Y, et al
Androgen Receptor-Mediated Paracrine Signaling Induces Regression of Blood Vessels in the Dermal Papilla in Androgenetic Alopecia.
J Invest Dermatol. 2022;142:2088-2099.
PubMed Abstract available

VERMEER MCSC, Sillje HHW, Pas HH, Andrei D, et al
Keratin 14 Degradation and Aging in Epidermolysis Bullosa Simplex due to KLHL24 Gain-of-Function Variants.
J Invest Dermatol. 2022;142:2271-2274.
PubMed

EGGERMONT C, Wakkee M, Bruggink A, Voorham Q, et al
Development and Validation of an Algorithm to Identify Patients with Advanced Cutaneous Squamous Cell Carcinoma from Pathology Reports.
J Invest Dermatol. 2022 Aug 1. pii: S0022-202X(22)01686.
PubMed Abstract available

July 2022

TUUSA J, Kokkonen N, Mattila A, Huilaja L, et al
Dipeptidylpeptidase-4 inhibitor-associated bullous pemphigoid is characterized by an altered expression of cytokines in the skin.
J Invest Dermatol. 2022 Jul 31. pii: S0022-202X(22)01681.
PubMed Abstract available

SHO Y, Sakai T, Sato T, Sonezaki M, et al
Stratum corneum ceramide profiles provide reliable indicators of remission and potential flares in atopic dermatitis.
J Invest Dermatol. 2022 Jul 20. pii: S0022-202X(22)01664.
PubMed Abstract available

HUANG S, Zhen Y, Yin X, Yang Z, et al
KMT2C induced by FABP5P3 aggravates keratinocyte hyperproliferation and psoriasiform skin inflammation via upregulating transcription of PIK3R3.
J Invest Dermatol. 2022 Jul 20. pii: S0022-202X(22)01683.
PubMed Abstract available

XIAO Y, Jing D, Tang Z, Peng C, et al
Serum lipids and risk of incident psoriasis: a prospective cohort study from the UK Biobank study and Mendelian randomization analysis.
J Invest Dermatol. 2022 Jul 15. pii: S0022-202X(22)01667.
PubMed Abstract available

PERU S, Prochazkova-Carlotti M, Cherrier F, Velazquez J, et al
Cutaneous Lymphocyte Antigen (CLA) is a potential therapeutic target in Cutaneous T Cell Lymphoma.
J Invest Dermatol. 2022 Jul 15. pii: S0022-202X(22)01668.
PubMed Abstract available

GATHER L, Nath N, Falckenhayn C, Oterino-Sogo S, et al
Macrophages are polarized towards an inflammatory phenotype by their aged microenvironment in the human skin.
J Invest Dermatol. 2022 Jul 15. pii: S0022-202X(22)01676.
PubMed Abstract available

KAMIYA S, Ikegami I, Yanagi M, Takaki H, et al
Functional interplay between IL-9 and peptide YY contributes to chronic skin inflammation.
J Invest Dermatol. 2022 Jul 15. pii: S0022-202X(22)01673.
PubMed Abstract available

BEEBE E, Motamed Z, Opitz L, Cheng PF, et al
Defining the molecular landscape of cancer-associated stroma in cutaneous squamous cell carcinoma.
J Invest Dermatol. 2022 Jul 15. pii: S0022-202X(22)01669.
PubMed Abstract available

OLYDAM JI, de Wijs LEM, Dik WA, Ropke MA, et al
EASI p-EASI: predicting disease severity in atopic dermatitis patients treated with tralokinumab.
J Invest Dermatol. 2022 Jul 14. pii: S0022-202X(22)01649.
PubMed

HIKINO K, Tanaka N, Koido M, Tomizuka K, et al
Genetic architectures underlie onset age of atopic dermatitis.
J Invest Dermatol. 2022 Jul 13. pii: S0022-202X(22)01662.
PubMed

CHOUSAKOS E, Kose K, Kurtansky NR, Dusza SW, et al
ANALYZING THE SPATIAL RANDOMNESS IN THE DISTRIBUTION OF ACQUIRED MELANOCYTIC NEOPLASMS.
J Invest Dermatol. 2022 Jul 13. pii: S0022-202X(22)01663.
PubMed Abstract available

TANAKA R, Ichimura Y, Kubota N, Konishi R, et al
The role of programmed cell death ligand-1 on Langerhans cells in the regulation of psoriasis.
J Invest Dermatol. 2022 Jul 5. pii: S0022-202X(22)01645.
PubMed Abstract available

SEVERN MM, Cho YK, Manzer HS, Bunch ZL, et al
The commensal Staphylococcus warneri makes peptide inhibitors of MRSA quorum sensing that protect skin from atopic or necrotic damage.
J Invest Dermatol. 2022 Jul 5. pii: S0022-202X(22)01646.
PubMed

QUE L, Li Y, Dainichi T, Kukimoto I, et al
IFN-gammaInduced APOBEC3B Contributes to Merkel Cell Polyomavirus Genome Mutagenesis in Merkel Cell Carcinoma.
J Invest Dermatol. 2022;142:1793-1803.
PubMed Abstract available

ZHAO Z, Liu T, Liang Y, Cui W, et al
N2-Polarized Neutrophils Reduce Inflammation in Rosacea by Regulating Vascular Factors and Proliferation of CD4(+) T Cells.
J Invest Dermatol. 2022;142:1835-1844.
PubMed Abstract available

LI W, Wang T, Huang WB, Li FG, et al
Malassezia globosa Activates NLRP3 Inflammasome in Human Sebocytes.
J Invest Dermatol. 2022;142:2042-2046.
PubMed

PU W, Zhang R, Ma Y, Liu Q, et al
Genetic Associations of Non-Major Histocompatibility Complex Susceptibility Loci with Systemic Sclerosis in a Han Chinese Population.
J Invest Dermatol. 2022;142:2039-2042.
PubMed

CHITSAZZADEH V, Nguyen TN, de Mingo Pulido A, Bittencourt BB, et al
miR-181a Promotes Multiple Protumorigenic Functions by Targeting TGFbetaR3.
J Invest Dermatol. 2022;142:1956-1965.
PubMed Abstract available

KASE Y, Takahashi H, Ito H, Kamata A, et al
Intravenous Ig Regulates Anti-Desmoglein 3 IgG Production in B220(-) Antibody-Producing Cells in Mice with Pemphigus Vulgaris.
J Invest Dermatol. 2022;142:1786-1792.
PubMed Abstract available

GARNER DC, Niu J, Stender CF, Hinkston CL, et al
Association between Obesity and Sunburn Diagnoses: A Cross-Sectional Analysis in a Large Claims Dataset.
J Invest Dermatol. 2022;142:2034-2036.
PubMed

GOSTYNSKI A, Diercks GFH, Escamez MJ, Chandran NS, et al
Natural Occurrence of Autoantibodies against Basement Membrane Proteins in Epidermolysis Bullosa.
J Invest Dermatol. 2022;142:2014-2019.
PubMed

CORREA-GALLEGOS D, Machens HG, Rinkevich Y
States and Fates of Skin Fibroblasts Revealed through Chromatin Accessibility.
J Invest Dermatol. 2022;142:1767-1770.
PubMed

JOHNSON JL, Tschachler E
Goodbye Simple: Introducing the "Methods and Techniques for Skin Research" Series.
J Invest Dermatol. 2022;142:1761-1762.
PubMed

HORIKAWA H, Amagai M
T Helper 17/T Helper 22Skewed Inflammation with Epidermal Barrier Dysfunction in Nonmajor Inherited Ichthyosis Subtypes.
J Invest Dermatol. 2022 Jul 1. pii: S0022-202X(22)00378.
PubMed

June 2022

HE Y, Kim J, Tacconi C, Moody J, et al
Mediators of capillary-to-venule conversion in the chronic inflammatory skin disease psoriasis.
J Invest Dermatol. 2022 Jun 28. pii: S0022-202X(22)01542.
PubMed Abstract available

ESSIEN KI, Katz EL, Strassner JP, Harris JE, et al
T regulatory cells require CCR6 for skin migration and local suppression of vitiligo.
J Invest Dermatol. 2022 Jun 28. pii: S0022-202X(22)01545.
PubMed Abstract available

MORIMOTO A, Fukuda K, Ito Y, Tahara U, et al
Microbiota-Independent Spontaneous Dermatitis Associated With Increased Sebaceous Lipid Production in Tmem79-Deficient Mice.
J Invest Dermatol. 2022 Jun 22. pii: S0022-202X(22)01588.
PubMed Abstract available

ZOBIRI O, Zucchi H, Dimitrov A, Marrot L, et al
Repeated Exposures to UVA1 and PM-Associated Pollutants Trigger Epidermal Barrier Dysfunction in Skin Epithelialization Model.
J Invest Dermatol. 2022 Jun 21. pii: S0022-202X(22)01547.
PubMed

BERG AR, Hong CG, Svirydava M, Li H, et al
Association of S100A8/A9 with lipid-rich necrotic core and treatment with biologic therapy in patients with psoriasis: results from an observational cohort study.
J Invest Dermatol. 2022 Jun 21. pii: S0022-202X(22)01527.
PubMed Abstract available

FATIMA I, Chen G, Botchkareva NV, Sharov AA, et al
Skin Aging in Long-Lived Naked Mole-Rats is Accompanied by Increased Expression of Longevity-Associated and Tumor Suppressor Genes.
J Invest Dermatol. 2022 Jun 9. pii: S0022-202X(22)00402.
PubMed Abstract available

XUE S, Zhu R, Chen W, Yang H, et al
Inhibiting Keratinocyte-derived STAT6 Improved Atopic Dermatitis in Mice.
J Invest Dermatol. 2022 Jun 8. pii: S0022-202X(22)01530.
PubMed

DONG L, Zhou T, She Q, Nie X, et al
Circulating Exosomal miR-493-3p Affects Melanocyte Survival and Function by Regulating Epidermal Dopamine Concentration in Segmental Vitiligo.
J Invest Dermatol. 2022 Jun 8. pii: S0022-202X(22)01529.
PubMed Abstract available

BRUNO M, Davidson L, Koenen HJPM, van den Reek JMPA, et al
Immunological effects of anti-IL-17/12/23 therapy in patients with psoriasis complicated by Candida infections.
J Invest Dermatol. 2022 Jun 2. pii: S0022-202X(22)01525.
PubMed Abstract available

MEHTA NN, Gelfand JM
Is It Prime Time for Statin Therapy in Psoriasis?
J Invest Dermatol. 2022;142:1519-1522.
PubMed

SECREST AM, Chren MM
Incorporating Patient-Reported Outcomes as a Vital Sign for Dermatologic Clinical Care and Clinical Investigations.
J Invest Dermatol. 2022;142:1529-1532.
PubMed Abstract available

IKAWA T, Ichimura Y, Miyagawa T, Fukui Y, et al
The Contribution of LIGHT (TNFSF14) to the Development of Systemic Sclerosis by Modulating IL-6 and T Helper Type 1 Chemokine Expression in Dermal Fibroblasts.
J Invest Dermatol. 2022;142:1541-1551.
PubMed Abstract available

WEI A, Zhang T, Yuan Y, Qi Z, et al
Spectrum Analysis of Albinism Genes in a Large Cohort of Chinese Index Patients.
J Invest Dermatol. 2022;142:1752-1755.
PubMed

SINGH K, Maity P, Koroma AK, Basu A, et al
Angiogenin Released from ABCB5(+) Stromal Precursors Improves Healing of Diabetic Wounds by Promoting Angiogenesis.
J Invest Dermatol. 2022;142:1725-1736.
PubMed Abstract available

HAIN C, Stadler R, Kalinowski J
Sezary Syndrome Shows Whole Genome Duplication as a Late Event in Tumor Evolution.
J Invest Dermatol. 2022;142:1755-1758.
PubMed

PIPI E, Kasprick A, Iwata H, Goletz S, et al
Multiple Modes of Action Mediate the Therapeutic Effect of Intravenous IgG in Experimental Epidermolysis Bullosa Acquisita.
J Invest Dermatol. 2022;142:1552-1564.
PubMed Abstract available

NOLLET L, Van Gils M, Willaert A, Coucke PJ, et al
Minocycline Attenuates Excessive DNA Damage Response and Reduces Ectopic Calcification in Pseudoxanthoma Elasticum.
J Invest Dermatol. 2022;142:1629-1638.
PubMed Abstract available

PORTER M, Choshi P, Pedretti S, Chimbetete T, et al
IFN-gamma ELISpot in Severe Cutaneous Adverse Reactions to First-line Anti-tuberculosis Drugs in an HIV Endemic Setting.
J Invest Dermatol. 2022 Jun 1. pii: S0022-202X(22)01500.
PubMed Abstract available

May 2022

VERGANI E, Busico A, Dugo M, Devecchi A, et al
Genetic layout of melanoma lesions associates to BRAF/MEK-targeted therapy resistance and to transcriptional profiles.
J Invest Dermatol. 2022 May 25. pii: S0022-202X(22)00400.
PubMed Abstract available

XIE X, Chen L, Liu X, Wu Z, et al
PROPHYLACTIC EFFECT OF NITRIC OXIDE DONORS ON RAT MODELS OF EGFR INHIBITORS-INDUCED CUTANEOUS TOXICITIES.
J Invest Dermatol. 2022 May 23. pii: S0022-202X(22)00399.
PubMed Abstract available

ESHO T, Tufa SF, Kobbe B, Wohl AP, et al
Anchoring cords, a distinct suprastructure in the developing skin.
J Invest Dermatol. 2022 May 22. pii: S0022-202X(22)00398.
PubMed Abstract available

LE TK, Brown I, Goldberg R, Taylor MT, et al
Cutaneous Toxicities Associated with Immune Checkpoint Inhibitors: an Observational, Pharmacovigilance Study.
J Invest Dermatol. 2022 May 18. pii: S0022-202X(22)00389.
PubMed Abstract available

LERMAN I, Bawany F, Whitt W, Esaa F, et al
Prominent B cell signature differentiates discoid from subacute cutaneous lupus erythematosus.
J Invest Dermatol. 2022 May 17. pii: S0022-202X(22)00369.
PubMed Abstract available

KAINULAINEN K, Takabe P, Heikkinen S, Aaltonen N, et al
M1 macrophages induce pro-tumor inflammation in melanoma cells via TNFR-NF-kappaB signaling.
J Invest Dermatol. 2022 May 14. pii: S0022-202X(22)00393.
PubMed Abstract available

WILD J, Ringen J, Bieler T, Knopp T, et al
Epicutaneous application of Imiquimod to model psoriasis-like skin disease induces water-saving aestivation motifs and vascular inflammation.
J Invest Dermatol. 2022 May 14. pii: S0022-202X(22)00392.
PubMed

DONG X, Zeng W, Zhang W, Lan Y, et al
Opsin 3 Regulates Melanogenesis in Human Congenital Melanocytic Nevus Cells via Functional Interaction with BRAF(V600E).
J Invest Dermatol. 2022 May 13. pii: S0022-202X(22)00391.
PubMed Abstract available

CHEN Y, Chen W
Genome-wide integration of genetic and genomic studies of atopic dermatitis: Insights into genetic architecture and pathogenesis.
J Invest Dermatol. 2022 May 13. pii: S0022-202X(22)00390.
PubMed Abstract available

SAHUT-BARNOLA I, Lefrancois-Martinez AM, Dufour D, Jean-Marie BOTTO, et al
Steroidogenic factor-1 lineage origin of skin lesions in Carney complex syndrome.
J Invest Dermatol. 2022 May 11. pii: S0022-202X(22)00377.
PubMed Abstract available

THAKUR MA, Khandelwal AR, Gu X, Rho O, et al
Inhibition of Fibroblast Growth Factor Receptor Attenuates Ultraviolet B-Induced Skin Carcinogenesis.
J Invest Dermatol. 2022 May 9. pii: S0022-202X(22)00375.
PubMed Abstract available

FENINI G, Karakaya T, Hennig P, Di Filippo M, et al
NLRP1 Inflammasome Activation in Keratinocytes: Increasing Evidence of Important Roles in Inflammatory Skin Diseases and Immunity.
J Invest Dermatol. 2022 May 9. pii: S0022-202X(22)00276.
PubMed Abstract available

LING S, Xu B, Luo Y, Fang X, et al
Transglutaminase 3 attenuates skin inflammation in psoriasis by inhibiting NF-kappaB activation via p-STAT3-TET3 signaling.
J Invest Dermatol. 2022 May 8. pii: S0022-202X(22)00374.
PubMed Abstract available

WANG J, Li X, Zhang P, Yang T, et al
Chrna5 is overexpressed in psoriasis patients and promotes psoriasis-like inflammation in mouse models.
J Invest Dermatol. 2022 May 2. pii: S0022-202X(22)00368.
PubMed Abstract available

LENTSCH G, Baugh EG, Lee B, Aszterbaum M, et al
Research Techniques Made Simple: Emerging Imaging Technologies for Noninvasive Optical Biopsy of Human Skin.
J Invest Dermatol. 2022;142:1243-1252.
PubMed Abstract available

PALLER AS, Lai JS, Jackson K, Rangel SM, et al
Generation and Validation of the Patient-Reported Outcome Measurement Information System Itch Questionnaire-Child (PIQ-C) to Measure the Impact of Itch on Life Quality.
J Invest Dermatol. 2022;142:1309-1317.
PubMed Abstract available

SUTARIA N, Alphonse MP, Marani M, Parthasarathy V, et al
Cluster Analysis of Circulating Plasma Biomarkers in Prurigo Nodularis Reveals a Distinct Systemic Inflammatory Signature in African Americans.
J Invest Dermatol. 2022;142:1300-1308.
PubMed Abstract available

BOUDRA R, Woappi Y, Wang D, Xu S, et al
Regulation of 5-Hydroxymethylcytosine by TET2 Contributes to Squamous Cell Carcinoma Tumorigenesis.
J Invest Dermatol. 2022;142:1270-1279.
PubMed Abstract available

INGOLD N, Dusingize JC, Neale RE, Olsen CM, et al
Examining Evidence for a Causal Association between Telomere Length and Nevus Count.
J Invest Dermatol. 2022;142:1502-1505.
PubMed

April 2022

YU N, Qin H, Yu Y, Li Y, et al
A distinct immature low-density neutrophil population characterizes acute generalized pustular psoriasis.
J Invest Dermatol. 2022 Apr 29. pii: S0022-202X(22)00364.
PubMed

WERTH VP, Hejazi E, Pena SM, Haber J, et al
Safety and Efficacy of Lenabasum, a Cannabinoid Receptor Type 2 Agonist, in Dermatomyositis Patients with Refractory Skin Disease A Randomized Clinical Trial.
J Invest Dermatol. 2022 Apr 28. pii: S0022-202X(22)00295.
PubMed Abstract available

LIU Y, Chi W, Tao L, Wang G, et al
Ablation of H(+)/glucose Exporter SLC45A2 Enhances Melanosomal Glycolysis to Inhibit Melanin Biosynthesis and Promote Melanoma Metastasis.
J Invest Dermatol. 2022 Apr 22. pii: S0022-202X(22)00301.
PubMed Abstract available

MAVERAKIS E, Liakos W, Park D, Patel F, et al
The psoriasis glycome: differential expression of cholesterol particle glycans and IgA glycans linked to disease severity.
J Invest Dermatol. 2022 Apr 22. pii: S0022-202X(22)00303.
PubMed

CHANG GA, Robinson E, Wiggins JM, Zhang Y, et al
Associations between TERT promoter mutations and survival in superficial spreading and nodular melanomas in a large prospective patient cohort.
J Invest Dermatol. 2022 Apr 22. pii: S0022-202X(22)00304.
PubMed Abstract available

KIM M, Mikhaylov D, Rangel SM, Pavel AB, et al
Transcriptomic Analysis of the Major Orphan Ichthyosis Subtypes Reveals Shared Immune and Barrier Signatures.
J Invest Dermatol. 2022 Apr 11. pii: S0022-202X(22)00269.
PubMed Abstract available

LI G, Tang X, Zhang S, Deng Z, et al
Aging-conferred SIRT7 Decline Inhibits Rosacea-like Skin Inflammation via Modulating TLR2-NF-kappaB Signaling.
J Invest Dermatol. 2022 Apr 9. pii: S0022-202X(22)00273.
PubMed Abstract available

VOIGT AY, Emiola A, Johnson JS, Fleming ES, et al
Skin microbiome variation with cancer progression in human cutaneous squamous cell carcinoma.
J Invest Dermatol. 2022 Apr 4. pii: S0022-202X(22)00261.
PubMed Abstract available

LEE KJ, Stark MS
In Vivo Melanoma Cell Morphology and Tumor Aggressiveness: The Promise of Reflectance Confocal Microscopy in Reducing Unnecessary Excisions.
J Invest Dermatol. 2022 Apr 2. pii: S0022-202X(22)00079.
PubMed

TOVANABUTRA N, Bax CE, Feng R, Kushner CJ, et al
Temporal Outcomes after Rituximab Therapy for Pemphigus Vulgaris.
J Invest Dermatol. 2022;142:1058-1064.
PubMed Abstract available

GIRI S, Meitei HT, Mishra A, Lal G, et al
+Vgamma2(+) gammadelta T cells in the presence of anti-CD40L control surgical inflammation and promote skin allograft survival.
J Invest Dermatol. 2022 Apr 1. pii: S0022-202X(22)00259.
PubMed Abstract available

SCHMID B, Kunstner A, Fahnrich A, Busch H, et al
Longitudinal Characterization of the Fungal Skin Microbiota in Healthy Subjects Over the Period of One Year.
J Invest Dermatol. 2022 Apr 1. pii: S0022-202X(22)00257.
PubMed Abstract available

WANG J, Pajulas A, Fu Y, Adom D, et al
gammadelta T cell-mediated Wound Healing is Diminished by Allergic Skin Inflammation.
J Invest Dermatol. 2022 Apr 1. pii: S0022-202X(22)00255.
PubMed Abstract available

UDEY MC
Social Aspects of Scientific Investigation - Recent Compromises and Anticipated Recovery.
J Invest Dermatol. 2022;142:989-990.
PubMed

ZHENG A, Thibodeau PH
Commentary on Variants in the ABCC6 Gene Implicated in Pseudoxanthoma Elasticum, a Heritable Ectopic Mineralization Disorder.
J Invest Dermatol. 2022;142:1002-1003.
PubMed Abstract available

BROWN SJ
Atopic Eczema: How Genetic Studies Can Contribute to the Understanding of this Complex Trait.
J Invest Dermatol. 2022;142:1015-1019.
PubMed Abstract available

HAS C, Sayar SB, Zheng S, Chacon-Solano E, et al
Read-Through for Nonsense Mutations in Type XVII CollagenDeficient Junctional Epidermolysis Bullosa.
J Invest Dermatol. 2022;142:1227-1230.
PubMed

SZILVESZTER KP, Vikar S, Horvath AI, Helyes Z, et al
Phospholipase Cgamma2 Is Essential for Experimental Models of Epidermolysis Bullosa Acquisita.
J Invest Dermatol. 2022;142:1114-1125.
PubMed Abstract available

GRETZMEIER C, Pin D, Kern JS, Chen M, et al
Systemic Collagen VII Replacement Therapy for Advanced Recessive Dystrophic Epidermolysis Bullosa.
J Invest Dermatol. 2022;142:1094-1102.
PubMed Abstract available

MESSINGHAM KN, Cahill MP, Kilgore SH, Munjal A, et al
TSST-1(+)Staphylococcus aureus in Bullous Pemphigoid.
J Invest Dermatol. 2022;142:1032-1039.
PubMed Abstract available

KOWAL L, Huang J, Luo H, Singh J, et al
Functional Assessment of Missense Variants in the ABCC6 Gene Implicated in Pseudoxanthoma Elasticum, a Heritable Ectopic Mineralization Disorder.
J Invest Dermatol. 2022;142:1085-1093.
PubMed Abstract available

SAITO M, Sada A, Fukuyo M, Aoki K, et al
PHLDA3 Is an Important Downstream Mediator of p53 in Squamous Cell Carcinogenesis.
J Invest Dermatol. 2022;142:1040-1049.
PubMed Abstract available

ABIGNANO G, Green L, Eng S, Emery P, et al
Nailfold Microvascular Imaging by Dynamic Optical Coherence Tomography in Systemic Sclerosis: A Case-Controlled Pilot Study.
J Invest Dermatol. 2022;142:1050-1057.
PubMed Abstract available

LOPEZ KOSTKA S, Kautz-Neu K, Yogev N, Lukas D, et al
Exclusive Expression of MyD88 on Dendritic Cells Is Sufficient to Induce Protection against Experimental Leishmaniasis.
J Invest Dermatol. 2022;142:1230-1233.
PubMed

ORTEGA-LOAYZA AG, Friedman MA, Reese AM, Liu Y, et al
Molecular and Cellular Characterization of Pyoderma Gangrenosum: Implications for the Use of Gene Expression.
J Invest Dermatol. 2022;142:1217-1220.
PubMed

March 2022

CURRIE SM, Stegmeyer RI, Mildner K, Breitsprecher L, et al
Confocal Real-Time Analysis of Cutaneous Platelet Recruitment during Immune-Complex-Mediated Inflammation.
J Invest Dermatol. 2022 Mar 31. pii: S0022-202X(22)00254.
PubMed Abstract available

CHEON SY, Park JH, Ameri AH, Lee RT, et al
IL-33/regulatory T cell axis suppresses skin fibrosis.
J Invest Dermatol. 2022 Mar 24. pii: S0022-202X(22)00207.
PubMed Abstract available

LEMAN G, Pavel P, Hermann M, Crumrine D, et al
Mitochondrial activity is up-regulated in nonlesional atopic dermatitis and amenable to therapeutic intervention.
J Invest Dermatol. 2022 Mar 24. pii: S0022-202X(22)00205.
PubMed Abstract available

CHENG HM, Honda T, Asahina R, Miyake T, et al
In-vivo Imaging of CD8(+) T cell-mediated Keratinocyte Apoptosis in Graft-Versus Host Disease-like Dermatitis in Involucrin-mOVA Mice.
J Invest Dermatol. 2022 Mar 24. pii: S0022-202X(22)00209.
PubMed

BRENNER E, Rocken M
A Commotion in the Skin: Developing Melanoma Immunotherapies.
J Invest Dermatol. 2022 Mar 23. pii: S0022-202X(22)00097.
PubMed Abstract available

HUANG YZ, Zheng YX, Zhou Y, Xu F, et al
OAS1, OAS2, and OAS3 Contribute to Epidermal Keratinocyte Proliferation by Regulating Cell Cycle and Augment Type I Interferon-Induced JAK1-STAT1 Phosphorylation in Psoriasis.
J Invest Dermatol. 2022 Mar 16. pii: S0022-202X(22)00204.
PubMed Abstract available

LEUS AJG, van Dijk BAC, Postmus D, Plaat BEC, et al
"Prediction of poor outcome for cutaneous squamous cell carcinoma of the head and neck comparing classification systems: a competing risk analysis".
J Invest Dermatol. 2022 Mar 15. pii: S0022-202X(22)00199.
PubMed

YU Z, Yu Q, Xu H, Dai X, et al
IL-17A promotes Psoriasis-associated Keratinocyte Proliferation via ACT1-depedent Activation of YAP-AREG Axis.
J Invest Dermatol. 2022 Mar 15. pii: S0022-202X(22)00201.
PubMed Abstract available

XU P, Wang C, Xiang W, Liang Y, et al
P2RY6 has a critical role in mouse skin carcinogenesis by regulating the YAP and beta-catenin signaling pathways.
J Invest Dermatol. 2022 Mar 15. pii: S0022-202X(22)00202.
PubMed Abstract available

TAKESHITA J, Augustin M, de Jong EMGJ, Lafferty KP, et al
Health-related quality of life differs by race/ethnicity in North American patients with psoriasis: results from PSOLAR.
J Invest Dermatol. 2022 Mar 15. pii: S0022-202X(22)00193.
PubMed

WOODS K, Cait A, Gell K, Naidoo K, et al
Goat milk-derived lipids restrain NKT cell-dependent eosinophilic inflammation in a murine model of atopic dermatitis.
J Invest Dermatol. 2022 Mar 14. pii: S0022-202X(22)00200.
PubMed

HOCHGERNER M, Bauer T, Zyulina V, Glitzner E, et al
BMPR1a is required for the optimal TGF-beta1 dependent CD207(+) Langerhans cell differentiation and limits skin inflammation via CD11c(+) cells.
J Invest Dermatol. 2022 Mar 14. pii: S0022-202X(22)00195.
PubMed Abstract available

YOUSSEFIAN L, Saeidian AH, Tavasoli AR, Kalamati E, et al
Recalcitrant Cutaneous Warts in a Family with Inherited ICOS Deficiency.
J Invest Dermatol. 2022 Mar 8. pii: S0022-202X(22)00176.
PubMed Abstract available

VAN DER KRAAIJ GE, Busard CI, van den Reek J, Menting SP, et al
Adalimumab with methotrexate versus adalimumab monotherapy in psoriasis: First-year results of a single-blind randomized controlled trial.
J Invest Dermatol. 2022 Mar 8. pii: S0022-202X(22)00177.
PubMed Abstract available

SUTARIA N, Alphonse MP, Roh YS, Choi J, et al
Cutaneous transcriptomics identifies fibroproliferative and neurovascular gene dysregulation in prurigo nodularis compared to psoriasis and atopic dermatitis.
J Invest Dermatol. 2022 Mar 4. pii: S0022-202X(22)00175.
PubMed

VAN DE KERKHOF PC
From Empirical to Pathogenesis-Based Treatments for Psoriasis.
J Invest Dermatol. 2022 Mar 3. pii: S0022-202X(22)00082.
PubMed Abstract available

GONZALEZ-PEREZ R, Poza-Guedes P, Pineda F, Castillo M, et al
Atopic Dermatitis and Frequency of Der p 11 Binding as a Major Allergen Revisited.
J Invest Dermatol. 2022;142.
PubMed

JIANG TT, Akilov OE
Exhausted Markers in Cutaneous T-Cell Lymphoma: The Face that Launched a Thousand Ships.
J Invest Dermatol. 2022;142.
PubMed Abstract available

GATTINGER P, Huang HJ, Valenta R, Vrtala S, et al
Response to Gonzalez-Perez et al.
J Invest Dermatol. 2022;142.
PubMed

FRANTZ WT, Ceol CJ
Research Techniques Made Simple: Zebrafish Models for Human Dermatologic Disease.
J Invest Dermatol. 2022;142.
PubMed Abstract available

FERNANDEZ-RUIZ R, Niewold TB
Type I Interferons in Autoimmunity.
J Invest Dermatol. 2022;142.
PubMed Abstract available

TSAI KY
The Origins of Merkel Cell Carcinoma: Defining Paths to the Neuroendocrine Phenotype.
J Invest Dermatol. 2022;142.
PubMed Abstract available

SAVIC S, Coe J, Laws P
Autoinflammation: Interferonopathies and Other Autoinflammatory Diseases.
J Invest Dermatol. 2022;142.
PubMed Abstract available

MIZUKAWA Y, Aoyama Y, Takahashi H, Takahashi R, et al
Risk of Progression to Autoimmune Disease in Severe Drug Eruption: Risk Factors and the Factor-Guided Stratification.
J Invest Dermatol. 2022;142.
PubMed Abstract available

ELLEBRECHT CT, Maseda D, Payne AS
Pemphigus and Pemphigoid: From Disease Mechanisms to Druggable Pathways.
J Invest Dermatol. 2022;142.
PubMed Abstract available

FREW JW
Autoantibody-Mediated Macrophage Responses Provide the Missing Link between Innate and Adaptive Immune Dysfunction in Hidradenitis Suppurativa.
J Invest Dermatol. 2022;142.
PubMed Abstract available

VICARI E, Haeberle S, Bolduan V, Ramcke T, et al
Pathogenic Autoantibody Derived from Regulatory T CellDeficient Scurfy Mice Targets Type VII Collagen and Leads to Epidermolysis Bullosa AcquisitaLike Blistering Disease.
J Invest Dermatol. 2022;142.
PubMed

CARMONA-RIVERA C, O'Neil LJ, Patino-Martinez E, Shipman WD, et al
Autoantibodies Present in Hidradenitis Suppurativa Correlate with Disease Severity and Promote the Release of Proinflammatory Cytokines in Macrophages.
J Invest Dermatol. 2022;142.
PubMed Abstract available

LI D, Cheng S, Pei Y, Sommar P, et al
Single-Cell Analysis Reveals Major Histocompatibility Complex IIExpressing Keratinocytes in Pressure Ulcers with Worse Healing Outcomes.
J Invest Dermatol. 2022;142.
PubMed Abstract available

TSENG PY, Hoon MA
Specific beta-Defensins Stimulate Pruritus through Activation of Sensory Neurons.
J Invest Dermatol. 2022;142.
PubMed Abstract available

KERVARREC T, Appenzeller S, Samimi M, Sarma B, et al
Merkel Cell PolyomavirusNegative Merkel Cell Carcinoma Originating from In Situ Squamous Cell Carcinoma: A Keratinocytic Tumor with Neuroendocrine Differentiation.
J Invest Dermatol. 2022;142.
PubMed Abstract available

KIM YS, Shin S, Jung SH, Park YM, et al
Genomic Progression of Precancerous Actinic Keratosis to Squamous Cell Carcinoma.
J Invest Dermatol. 2022;142.
PubMed Abstract available

HARMS PW, Verhaegen ME, Vo JN, Tien JC, et al
Viral Status Predicts the Patterns of Genome Methylation and Decitabine Response in Merkel Cell Carcinoma.
J Invest Dermatol. 2022;142.
PubMed Abstract available

BERNDT N, Wolf C, Fischer K, Cura Costa E, et al
Photosensitivity and cGAS-Dependent IFN-1 Activation in Patients with Lupus and TREX1 Deficiency.
J Invest Dermatol. 2022;142.
PubMed Abstract available

HUDEMANN C, Maglie R, Llamazares-Prada M, Beckert B, et al
Human Desmocollin 3Specific IgG Antibodies Are Pathogenic in a Humanized HLA Class II Transgenic Mouse Model of Pemphigus.
J Invest Dermatol. 2022;142.
PubMed Abstract available

ESTADT SN, Maz MP, Musai J, Kahlenberg JM, et al
Mechanisms of Photosensitivity in Autoimmunity.
J Invest Dermatol. 2022;142.
PubMed Abstract available

WILLEMSEN M, Post NF, van Uden NOP, Narayan VS, et al
Immunophenotypic Analysis Reveals Differences in Circulating Immune Cells in the Peripheral Blood of Patients with Segmental and Nonsegmental Vitiligo.
J Invest Dermatol. 2022;142.
PubMed Abstract available

GENARDI S, Morgun E, Wang CR
CD1-Restricted T Cells in Inflammatory Skin Diseases.
J Invest Dermatol. 2022;142.
PubMed Abstract available

February 2022

OKUMURA K, Saito M, Isogai E, Tokunaga Y, et al
Functional polymorphism in Pak1-3'UTR alters skin tumor susceptibility by alternative polyadenylation.
J Invest Dermatol. 2022 Feb 28. pii: S0022-202X(22)00174.
PubMed Abstract available

SUHRKAMP I, Morrison PJ, Assmann JC, Schwaninger M, et al
ORAL DIMETHYL FUMARATE TARGETS HCA2-EXPRESSING SKIN CELLS IN THE IMIQUIMOD MOUSE MODEL.
J Invest Dermatol. 2022 Feb 18. pii: S0022-202X(22)00120.
PubMed

KAMADA H, Yasuhira S, Shibazaki M, Amano H, et al
DUSP4 inactivation leads to reduced ERK activity via the upregulation of DUSP6 in melanoma cells.
J Invest Dermatol. 2022 Feb 18. pii: S0022-202X(22)00126.
PubMed Abstract available

HATTON JN, Sargen MR, Frone MN, de Andrade KC, et al
Spectrum and incidence of skin cancer among individuals with Li-Fraumeni syndrome.
J Invest Dermatol. 2022 Feb 17. pii: S0022-202X(22)00123.
PubMed

HAN SS, Kim YJ, Moon IJ, Jung JM, et al
Evaluation of Artificial Intelligence-assisted Diagnosis of Skin Neoplasms - a single-center, paralleled, unmasked, randomized controlled trial.
J Invest Dermatol. 2022 Feb 17. pii: S0022-202X(22)00122.
PubMed Abstract available

YEPES S, Tucker MA, Koka H, Xiao Y, et al
Integrated Analysis of Co-expression and Exome Sequencing to Prioritize Susceptibility Genes for Familial Cutaneous Melanoma.
J Invest Dermatol. 2022 Feb 15. pii: S0022-202X(22)00118.
PubMed Abstract available

TAN PC, Zhou SB, Ou MY, He JZ, et al
Mechanical stretching can modify the papillary dermis pattern and papillary fibroblast characteristics during skin regeneration.
J Invest Dermatol. 2022 Feb 15. pii: S0022-202X(22)00117.
PubMed Abstract available

WANG P, Theocharidis G, Vlachos IS, Kounas K, et al
Exosomes Derived from Epidermal Stem Cells Improve Diabetic Wound Healing.
J Invest Dermatol. 2022 Feb 15. pii: S0022-202X(22)00119.
PubMed Abstract available

WIKRAMANAYAKE TC, Nicu C, Gherardini J, Mello ACGCV, et al
Mitochondrially Localized MPZL3 Functions as a Negative Regulator of Sebaceous Gland Size and Sebocyte Proliferation.
J Invest Dermatol. 2022 Feb 13. pii: S0022-202X(22)00101.
PubMed

KIM TH, Park TJ, Kweon YY, Baek DJ, et al
Age-dependent sequential increase of senescent cells in the skin.
J Invest Dermatol. 2022 Feb 10. pii: S0022-202X(22)00100.
PubMed

LAZAR I, Clement E, Carrie L, Esteve D, et al
Adipocyte extracellular vesicles decrease p16(INK4A) in melanoma: an additional link between obesity and cancer.
J Invest Dermatol. 2022 Feb 9. pii: S0022-202X(22)00099.
PubMed Abstract available

MOK BR, Kim AR, Baek SH, Ahn JH, et al
Profilin-1 prevents psoriasis pathogenesis through IkappaBzeta regulation.
J Invest Dermatol. 2022 Feb 8. pii: S0022-202X(22)00095.
PubMed Abstract available

WANG D, Fu Z, Gao L, Zeng J, et al
Increased IRF9-STAT2 signaling leads to adaptive resistance toward targeted therapy in melanoma by restraining GSDME-dependent pyroptosis.
J Invest Dermatol. 2022 Feb 8. pii: S0022-202X(22)00096.
PubMed Abstract available

RAITA A, Haggqvist IM, Joronen H, Nikkola V, et al
DIURNAL PREFERENCE CONTRIBUTES TO MAXIMAL ULTRAVIOLET RADIATION B SENSITIVITY BY THE HOUR OF THE DAY IN HUMAN SKIN IN VIVO.
J Invest Dermatol. 2022 Feb 7. pii: S0022-202X(22)00091.
PubMed

QIAO P, Zhang C, Yu J, Shao S, et al
Quinolinic acid, a tryptophan metabolite of the skin microbiota, negatively regulates the NLRP3 inflammasome through the aryl hydrocarbon receptor in psoriasis.
J Invest Dermatol. 2022 Feb 7. pii: S0022-202X(22)00020.
PubMed Abstract available

YU KK, Smith NP, Essien SV, Teague JE, et al
IL-32 supports the survival of malignant T cells in cutaneous T cell lymphoma.
J Invest Dermatol. 2022 Feb 7. pii: S0022-202X(22)00019.
PubMed

ONOUFRIADIS A, McGrath JA
The past and future of rare skin disease research/therapy.
J Invest Dermatol. 2022 Feb 5. pii: S0022-202X(22)00087.
PubMed Abstract available

LI Y, Wu J, Tian Y, Zhu Q, et al
Med1 downregulation contributes to TGF-beta-induced metastasis by inhibiting Smad2 ubiquitination degradation in cutaneous melanoma.
J Invest Dermatol. 2022 Feb 4. pii: S0022-202X(22)00081.
PubMed Abstract available

BRUMFIEL CM, Patel MH, Severson KJ, Zhang N, et al
Ruxolitinib cream in the treatment of cutaneous lichen planus: A prospective, open-label study.
J Invest Dermatol. 2022 Feb 4. pii: S0022-202X(22)00083.
PubMed Abstract available

EMRAN AA, Fisher DE
Dual Targeting with EZH2 Inhibitor and STING Agonist to Treat Melanoma.
J Invest Dermatol. 2022 Feb 4. pii: S0022-202X(21)02378.
PubMed Abstract available

AZIN M, Demehri S
STK11 Loss: A Novel Mechanism for Melanoma Metastasis with Therapeutic Implications.
J Invest Dermatol. 2022 Feb 4. pii: S0022-202X(21)02345.
PubMed Abstract available

RAGOT H, Hovnanian A
Drug Repurposing Reveals mTOR Inhibition as a Promising Strategy for Epidermolysis Bullosa Simplex.
J Invest Dermatol. 2022;142:275-278.
PubMed Abstract available

LEE GH, Lekwuttikarn R, Tafoya E, Martin M, et al
Transcriptomic Repositioning Analysis Identifies mTOR Inhibitor as Potential Therapy for Epidermolysis Bullosa Simplex.
J Invest Dermatol. 2022;142:382-389.
PubMed Abstract available

GUIDA S, Guida G, Goding CR
MC1R Functions, Expression, and Implications for Targeted Therapy.
J Invest Dermatol. 2022;142:293-302.
PubMed Abstract available

XU G, Luo Y, Wu W, Liu X, et al
The Evolution of Acquired Resistance to BRAF(V600E) kinase inhibitor Is Sustained by IGF1-Driven Tumor Vascular Remodeling.
J Invest Dermatol. 2022;142:445-458.
PubMed Abstract available

PADHI A, Srivastava A, Ramesh A, Ehrstrom M, et al
IL-22 Downregulates Peptidylarginine Deiminase-1 in Human Keratinocytes: Adding Another Piece to the IL-22 Puzzle in Epidermal Barrier Formation.
J Invest Dermatol. 2022;142:333-342.
PubMed Abstract available

TOPP J, Apfelbacher C, Stander S, Augustin M, et al
Measurement Properties of Patient-Reported Outcome Measures for Pruritus: An Updated Systematic Review.
J Invest Dermatol. 2022;142:343-354.
PubMed Abstract available

ANGIOLILLI C, Leijten EFA, Bekker CPJ, Eeftink E, et al
ZFP36 Family Members Regulate the Proinflammatory Features of Psoriatic Dermal Fibroblasts.
J Invest Dermatol. 2022;142:402-413.
PubMed Abstract available

MA J, Chen J, Xue K, Yu C, et al
Lipocalin 2 Mediates Skin Inflammation in Psoriasis via the SREBP2-NLRC4 Axis.
J Invest Dermatol. 2022 Feb 1. pii: S0022-202X(22)00080.
PubMed Abstract available

January 2022

OLSEN CM, Whiteman DC
Cutaneous Melanoma in White Americans: A Tale of Two Epidemics.
J Invest Dermatol. 2022 Jan 30. pii: S0022-202X(22)00003.
PubMed Abstract available

CUI J, Zhao Q, Song Z, Chen Z, et al
KLHL24-mediated hair follicle stem cells structural disruption causes alopecia.
J Invest Dermatol. 2022 Jan 20. pii: S0022-202X(22)00016.
PubMed Abstract available

WALKER GJ, Galbraith JA, Baz B, Ferguson B, et al
A murine Kitl allele regulates skin mast cell density across 58 collaborative mouse cross strains.
J Invest Dermatol. 2022 Jan 19. pii: S0022-202X(22)00006.
PubMed

PESKOLLER M, Bhosale A, Gobel K, Lohr J, et al
ESDR 50th Anniversary Lecture summary: How to build and regenerate a functional skin barrier: the adhesive and cell shaping travels of a keratinocyte.
J Invest Dermatol. 2022 Jan 17. pii: S0022-202X(22)00010.
PubMed Abstract available

CARTER LM, McGonagle D, Vital EM, Wittmann M, et al
Applying Early Intervention Strategies to Autoimmune Skin Diseases. Is the Window of Opportunity Preclinical? A Dermato-Rheumatology Perspective.
J Invest Dermatol. 2022 Jan 13. pii: S0022-202X(21)02532.
PubMed Abstract available

YIN Q, Sun L, Cai X, Lou F, et al
Lidocaine Ameliorates Psoriasis by Obstructing Pathogenic CGRP Signaling-Mediated Sensory Neuron-Dendritic Cell Communication.
J Invest Dermatol. 2022 Jan 12. pii: S0022-202X(22)00007.
PubMed Abstract available

CHU YS, Lee S, Lee SG, Chung KY, et al
Deep Learning Algorithms for Predicting Breslow Thickness from Dermoscopic Images of Acral Lentiginous Melanomas.
J Invest Dermatol. 2022 Jan 12. pii: S0022-202X(22)00008.
PubMed

CARPENTER EL, Wyant MB, Indra A, Ito S, et al
Thioredoxin Reductase 1 Modulates Pigmentation and Photobiology of Murine Melanocytes in vivo.
J Invest Dermatol. 2022 Jan 11. pii: S0022-202X(21)02605.
PubMed Abstract available

BUSTOS MA, Hoon DSB
Prognostic Utility of CpG Island Hypermethylated Phenotype in Early-Stage Invasive Primary Melanomas.
J Invest Dermatol. 2022 Jan 11. pii: S0022-202X(21)02629.
PubMed Abstract available

PEREIRA MS, Redanz S, Kriegel MA
Skin Deep: The Role of the Microbiota in Cutaneous Autoimmunity.
J Invest Dermatol. 2022 Jan 10. pii: S0022-202X(21)02612.
PubMed Abstract available

ROGNONI E
Dermal Hedgehog Signaling in Papillary Fibroblasts: An Emerging Key Player in Skin Regeneration.
J Invest Dermatol. 2022 Jan 10. pii: S0022-202X(21)02625.
PubMed Abstract available

MINE K, Tun X, Hatano S, Noguchi N, et al
Dermal Vgamma6(+) gammadelta T17 Cells are Involved in Skin Pressure Ulcers in Mice.
J Invest Dermatol. 2022 Jan 7. pii: S0022-202X(22)00002.
PubMed

LEI V, Handfield C, Kwock JT, Kirchner SJ, et al
Skin Injury Activates A Rapid TRPV1-dependent Antiviral Protein Response.
J Invest Dermatol. 2022 Jan 7. pii: S0022-202X(21)02637.
PubMed Abstract available

MARCONI A, Quadri M, Farnetani F, Ciardo S, et al
In Vivo Melanoma Cell Morphology Reflects Molecular Signature and Tumor Aggressiveness.
J Invest Dermatol. 2022 Jan 7. pii: S0022-202X(21)02683.
PubMed Abstract available

BRESIN A, Caprini E, Russo G, Narducci MG, et al
Challenging Cutaneous T-Cell Lymphoma: What Animal Models Tell us So Far.
J Invest Dermatol. 2022 Jan 6. pii: S0022-202X(21)02615.
PubMed Abstract available

TAN KJ, Nakamizo S, Lee-Okada HC, Sato R, et al
A western diet alters skin ceramides and compromises the skin barrier in ears.
J Invest Dermatol. 2022 Jan 6. pii: S0022-202X(21)02634.
PubMed

ZHOU Q, Gong J, Bi J, Yang X, et al
Keratinocyte growth factor-2 regulates signal-transducing adaptor protein-2-mediated signal transducer and activator of transcription 3 signaling and reduces skin scar formation.
J Invest Dermatol. 2022 Jan 6. pii: S0022-202X(21)02635.
PubMed Abstract available

BECHMANN N, Calsina B, Richter S, Pietzsch J, et al
Therapeutic Potential of Nitric Oxide releasing Selective Estrogen Receptor Modulators (NO-SERMs) in Malignant Melanoma.
J Invest Dermatol. 2022 Jan 3. pii: S0022-202X(21)02691.
PubMed Abstract available

SOCHOROVA M, Vavrova K, Fedorova M, Ni Z, et al
Research Techniques Made Simple: Lipidomic Analysis in Skin Research.
J Invest Dermatol. 2022;142:4-11.
PubMed Abstract available

UDEY MC
Scratching the Five-Year Itch.
J Invest Dermatol. 2022;142:1.
PubMed

GUO CJ, Grabinski NS, Liu Q
Peripheral Mechanisms of Itch.
J Invest Dermatol. 2022;142:31-41.
PubMed Abstract available

MAMULADZE T, Kim BS
The Sensation of Itch: From Biological Discovery to Medical Treatment.
J Invest Dermatol. 2022;142:21-22.
PubMed

SHIBUYA R, Takimoto-Ito R, Kambe N, Kabashima K, et al
A New Era with the Development of Cytokine-Based Therapy for Pruritus.
J Invest Dermatol. 2022;142:47-52.
PubMed Abstract available

TSENG PY, Hoon MA
Interactions of the NeuroImmuneStromal Triad in Itch.
J Invest Dermatol. 2022;142:42-46.
PubMed Abstract available

MU D, Sun YG
Circuit Mechanisms of Itch in the Brain.
J Invest Dermatol. 2022;142:23-30.
PubMed Abstract available

GHARAEE-KERMANI M, Estadt SN, Tsoi LC, Wolf-Fortune SJ, et al
IFN-kappa Is a Rheostat for Development of Psoriasiform Inflammation.
J Invest Dermatol. 2022;142:155-165.
PubMed Abstract available

MISHRA SK
The Role of CNTNAP2 in Itch Sensation.
J Invest Dermatol. 2022;142:251-253.
PubMed

HANSEN UK, Lyngaa R, Ibrani D, Church C, et al
Extended T-Cell Epitope Landscape in Merkel Cell Polyomavirus Large T and Small T Oncoproteins Identified Uniquely in Patients with Cancer.
J Invest Dermatol. 2022;142:239-243.
PubMed

DAI X, Shiraishi K, Muto J, Utsunomiya R, et al
Nuclear IL-33 Plays an Important Role in IL-31Mediated Downregulation of FLG, Keratin 1, and Keratin 10 by Regulating Signal Transducer and Activator of Transcription 3 Activation in Human Keratinocytes.
J Invest Dermatol. 2022;142:136-144.
PubMed Abstract available

STRUNCK JL, Cutler B, Rajpal B, Kent G, et al
Pityriasis Rubra Pilaris Response to IL-17A Inhibition Is Associated with IL-17C and CCL20 Protein Levels.
J Invest Dermatol. 2022;142:235-239.
PubMed

December 2021

HASKAMP S, Frey B, Becker I, Schulz-Kuhnt A, et al
Transcriptomes of MPO-deficient patients with generalized pustular psoriasis reveals expansion of CD4+ cytotoxic T cells and an involvement of the complement system.
J Invest Dermatol. 2021 Dec 29. pii: S0022-202X(21)02639.
PubMed Abstract available

KUMPER M, Hessenthaler S, Zamek J, Niland S, et al
LOSS OF ENDOTHELIAL CELL MMP14 REDUCES MELANOMA GROWTH AND METASTASIS BY INCREASING TUMOR VESSEL STABILITY.
J Invest Dermatol. 2021 Dec 27. pii: S0022-202X(21)02633.
PubMed Abstract available

FANE ME, Chhabra Y, Spoerri L, Simmons JL, et al
Reciprocal regulation of BRN2 and NOTCH1/2 signaling synergistically drives melanoma cell migration and invasion.
J Invest Dermatol. 2021 Dec 24. pii: S0022-202X(21)02630.
PubMed Abstract available

GANGWAR RS, Gudjonsson JE, Ward NL
Mouse Models of Psoriasis: A Comprehensive Review.
J Invest Dermatol. 2021 Dec 22. pii: S0022-202X(21)01442.
PubMed Abstract available

CHONG BF, Werth V
Cutaneous Lupus Erythematosus and Dermatomyositis: Utilizing Assessment Tools for Treatment Efficacy.
J Invest Dermatol. 2021 Dec 21. pii: S0022-202X(21)02468.
PubMed Abstract available

WANG Y, Ramachandran V, Sui D, Xu K, et al
Evaluation of Plasma Interleukin-6 in Melanoma Patients as a Prognostic and Checkpoint Immunotherapy Predictive Biomarker.
J Invest Dermatol. 2021 Dec 21. pii: S0022-202X(21)02627.
PubMed

MUKHERJEE N, Dart CR, Amato CM, Honig-Frand A, et al
Expression differences in BCL2 family members between uveal and cutaneous melanomas account for varying sensitivity to BH3 mimetics.
J Invest Dermatol. 2021 Dec 20. pii: S0022-202X(21)02617.
PubMed Abstract available

NIEHUES H, van der Krieken DA, Ederveen THA, Jansen PAM, et al
Antimicrobial late cornified envelope (LCE) proteins: the psoriasis risk factor LCE3B/C-del affects microbiota composition.
J Invest Dermatol. 2021 Dec 20. pii: S0022-202X(21)02618.
PubMed Abstract available

YIN D, Hao J, Jin R, Yi Y, et al
Epidermal Fatty Acid Binding Protein Mediates Depilatory-Induced Acute Skin Inflammation.
J Invest Dermatol. 2021 Dec 20. pii: S0022-202X(21)02623.
PubMed Abstract available

FUJISAWA C, Hamanoue M, Kawano Y, Murata D, et al
The role for miRNA146b-5p in the attenuation of dermal fibrosis and angiogenesis by targeting PDGFRalpha in skin wounds.
J Invest Dermatol. 2021 Dec 17. pii: S0022-202X(21)02619.
PubMed Abstract available

THOMPSON SM, Phan QM, Winuthayanon S, Driskell IM, et al
Parallel single cell multi-omics analysis of neonatal skin reveals transitional fibroblast states that restricts differentiation into distinct fates.
J Invest Dermatol. 2021 Dec 16. pii: S0022-202X(21)02608.
PubMed Abstract available

HIROYASU S, Tsuruta D
Stabilization of Hemidesmosomal Proteins: A Possible Key Contributor to Wnt/beta-Catenin Pathway Action in the Skin.
J Invest Dermatol. 2021 Dec 13. pii: S0022-202X(21)02530.
PubMed Abstract available

KURTANSKY NR, Dusza SW, Halpern AC, Hartman RI, et al
An Epidemiologic Analysis of Melanoma Overdiagnosis in the United States, 1975-2017.
J Invest Dermatol. 2021 Dec 10. pii: S0022-202X(21)02610.
PubMed Abstract available

SORMANI L, Montaudie H, Blot L, Heim M, et al
CLEC12B is a melanocytic gene regulating the color of the skin.
J Invest Dermatol. 2021 Dec 8. pii: S0022-202X(21)02588.
PubMed Abstract available

HOWARD B, Bascom CC, Hu P, Binder RL, et al
Aging Associated Changes in the Adult Human Skin Microbiome and the Host Factors That Affect Skin Microbiome Composition.
J Invest Dermatol. 2021 Dec 7. pii: S0022-202X(21)02603.
PubMed Abstract available

HRISTOVA DM, Fukumoto T, Takemori C, Gao L, et al
NUMB AS A NEW THERAPEUTIC TARGET FOR MELANOMA.
J Invest Dermatol. 2021 Dec 6. pii: S0022-202X(21)02600.
PubMed Abstract available

CHHABRA G, Ahmad N
BRAF Inhibitors in Melanoma Management: When Friends Become Foes.
J Invest Dermatol. 2021 Dec 3. pii: S0022-202X(21)02485.
PubMed Abstract available

MUSE ME, Bergman DT, Salas LA, Tom LN, et al
Genome-scale DNA methylation analysis identifies repeat element alterations that modulate the genomic stability of melanocytic nevi.
J Invest Dermatol. 2021 Dec 3. pii: S0022-202X(21)02592.
PubMed Abstract available

CROITORU DO, Piguet V
Cathelicidin LL-37 Ignites Primed NLRP3 Inflammasomes in Rosacea.
J Invest Dermatol. 2021;141:2780-2782.
PubMed Abstract available

NELSON CA, Tomayko MM
Targeting the FcRn: A Novel Approach to the Treatment of Pemphigus.
J Invest Dermatol. 2021;141:2777-2780.
PubMed Abstract available

PRENS LM, Ardon CB, van Straalen KR, van der Zee HH, et al
No Evident Systemic Terminal Complement Pathway Activation in Hidradenitis Suppurativa.
J Invest Dermatol. 2021;141:2966-2969.
PubMed

EMTENANI S, Ghorbanalipoor S, Mayer-Hain S, Kridin K, et al
Pathogenic Activation and Therapeutic Blockage of FcalphaR-Expressing Polymorphonuclear Leukocytes in IgA Pemphigus.
J Invest Dermatol. 2021;141:2820-2828.
PubMed Abstract available

WERTH VP, Culton DA, Concha JSS, Graydon JS, et al
Safety, Tolerability, and Activity of ALXN1830 Targeting the Neonatal Fc Receptor in Chronic Pemphigus.
J Invest Dermatol. 2021;141:2858-2865.
PubMed Abstract available

TIEDE S, Hundt JE, Paus R
UDP-GlcNAc-1-Phosphotransferase Is a Clinically Important Regulator of Human and Mouse Hair Pigmentation.
J Invest Dermatol. 2021;141:2957-2965.
PubMed Abstract available

WU TT, Eldirany SA, Bunick CG, Teng JMC, et al
GenotypeStructurotypePhenotype Correlations in Patients with Pachyonychia Congenita.
J Invest Dermatol. 2021;141:2876-2884.
PubMed Abstract available

YOUSAF A, Tallman R, Katzman S, Brady C, et al
Genotype-Phenotype Correlation in Trichilemmal Cysts.
J Invest Dermatol. 2021;141:2983-2985.
PubMed

VARPULUOMA O, Jokelainen J, Huilaja L, Tasanen K, et al
GLP-1 Analogs and SGLT2 Inhibitors Do Not Increase Risk of Bullous Pemphigoid.
J Invest Dermatol. 2021;141:2969-2972.
PubMed

MELENDEZ-GONZALEZ MDM, Hamad J, Sayed C
Golimumab for the Treatment of Hidradenitis Suppurativa in Patients with Previous TNF-alpha Treatment Failure.
J Invest Dermatol. 2021;141:2975-2979.
PubMed

SEVIIRI M, Law MH, Ong JS, Gharahkhani P, et al
Polygenic Risk Scores Stratify Keratinocyte Cancer Risk among Solid Organ Transplant Recipients with Chronic Immunosuppression in a High Ultraviolet Radiation Environment.
J Invest Dermatol. 2021;141:2866-2875.
PubMed Abstract available

November 2021

MANYAK GA, Patel NH, Dey AK, Svirydava M, et al
Abdominal visceral adiposity is associated with coronary artery lipid-rich necrotic core partly mediated by bone marrow uptake of (18)F-FDG PET / CT in psoriasis.
J Invest Dermatol. 2021 Nov 29. pii: S0022-202X(21)02587.
PubMed

MA B, Anandasabapathy N
Immune Checkpoint Blockade and Skin Toxicity Pathogenesis.
J Invest Dermatol. 2021 Nov 26. pii: S0022-202X(21)02308.
PubMed Abstract available

UITTO J, Saeidian AH, Youssefian L, Saffarian Z, et al
Recalcitrant Warts, Epidermodysplasia Verruciformis, and the Tree-Man Syndrome: Phenotypic Spectrum of Cutaneous HPV Infections at the Intersection of Genetic Variability of Viral and Human Genomes.
J Invest Dermatol. 2021 Nov 26. pii: S0022-202X(21)02529.
PubMed Abstract available

VARNEY SD, Wu L, Longmate WM, DiPersio CM, et al
Loss of integrin alpha9beta1 on tumor keratinocytes enhances the stromal vasculature and growth of cutaneous tumors.
J Invest Dermatol. 2021 Nov 26. pii: S0022-202X(21)02534.
PubMed Abstract available

CONWAY K, Tsai YS, Edmiston SN, Parker JS, et al
Characterization of the CpG island hypermethylated phenotype (CIMP) subclass in primary melanomas.
J Invest Dermatol. 2021 Nov 26. pii: S0022-202X(21)02531.
PubMed Abstract available

BALAK DMW, Perez-Chada LM, Guo LN, Mita C, et al
Defining Psoriasis Remission Based on Histopathological and Molecular Criteria: A Systematic Literature Review.
J Invest Dermatol. 2021 Nov 24. pii: S0022-202X(21)02536.
PubMed

LIYANAGE U, MacGregor S, Bishop DT, Shi J, et al
Multi-trait genetic analysis identifies auto-immune loci associated with cutaneous melanoma.
J Invest Dermatol. 2021 Nov 20. pii: S0022-202X(21)02513.
PubMed Abstract available

SALOMAA T, Pemmari T, Maatta J, Kummola L, et al
IL-13Ralpha1 Suppresses Tumor Progression in Two-stage Skin Carcinogenesis Model by Regulating Regulatory T Cells.
J Invest Dermatol. 2021 Nov 19. pii: S0022-202X(21)02525.
PubMed Abstract available

TSOI LC, Xing X, Xing E, Wasikowski R, et al
Non-invasive tape-stripping with high-resolution RNA profiling effectively captures a pre-inflammatory state in nonlesional psoriatic skin.
J Invest Dermatol. 2021 Nov 19. pii: S0022-202X(21)02497.
PubMed Abstract available

JUSSILA AR, Zhang B, Caves E, Kirti S, et al
Skin fibrosis and recovery is dependent on Wnt activation via DPP4.
J Invest Dermatol. 2021 Nov 19. pii: S0022-202X(21)02487.
PubMed Abstract available

SHI Z, Wu X, Wu CY, Singh SP, et al
Bile acids improve psoriasiform dermatitis through inhibition of IL-17A expression and CCL20-CCR6 mediated trafficking of T cells.
J Invest Dermatol. 2021 Nov 19. pii: S0022-202X(21)02522.
PubMed Abstract available

GARSHICK MS, Drenkova K, Barrett TJ, Schlamp F, et al
A Randomized Open Label Clinical Trial of Lipid-Lowering Therapy in Psoriasis to Reduce Vascular Endothelial Inflammation.
J Invest Dermatol. 2021 Nov 19. pii: S0022-202X(21)02524.
PubMed

CUI T, Wang Y, Song P, Yi X, et al
HSF1 dependent autophagy activation contributes to the survival of melanocytes under oxidative stress in vitiligo.
J Invest Dermatol. 2021 Nov 12. pii: S0022-202X(21)02488.
PubMed Abstract available

BOKI H, Kimura T, Miyagaki T, Suga H, et al
Lymphatic dysfunction exacerbates cutaneous tumorigenesis and psoriasis-like skin inflammation through accumulation of inflammatory cytokines.
J Invest Dermatol. 2021 Nov 12. pii: S0022-202X(21)02472.
PubMed Abstract available

SUZUKI K, Suzuki K, Yabe Y, Iida K, et al
NF-kappaB1 contributes to imiquimod-induced psoriasis-like skin inflammation by inducing Vgamma4(+)Vdelta4(+)gammadeltaT17 cells.
J Invest Dermatol. 2021 Nov 11. pii: S0022-202X(21)02483.
PubMed Abstract available

HAN Z, Estephan RJ, Wu X, Su C, et al
MiRNA regulation of T cell exhaustion in cutaneous T cell lymphoma.
J Invest Dermatol. 2021 Nov 10. pii: S0022-202X(21)02479.
PubMed Abstract available

DOUROUDIS K, Ramessur R, Barbosa IA, Baudry D, et al
DIFFERENCES IN CLINICAL FEATURES AND COMORBID BURDEN BETWEEN HLA-C*06:02 CARRIER GROUPS IN MORE THAN 9,000 PEOPLE WITH PSORIASIS.
J Invest Dermatol. 2021 Nov 9. pii: S0022-202X(21)02473.
PubMed Abstract available

SHEN Y, Zhu Z, Cong W, Jiang M, et al
Phosphorylation of alpha-cateninS641 suppresses the NF-kappaB pathway in fibroblasts to activate skin wound repair.
J Invest Dermatol. 2021 Nov 9. pii: S0022-202X(21)02474.
PubMed Abstract available

ZHANG S, Sumpter TL, Kaplan DH
NeuronMast Cell Cross-Talk in the Skin.
J Invest Dermatol. 2021 Nov 6. pii: S0022-202X(21)02354.
PubMed Abstract available

LAUERMA A, Werner P, Wisgrill L, Fyhrquist N, et al
New Key Players in Irritant Contact Dermatitis: Residential Skin Cells and Neutrophils Drive Inflammation.
J Invest Dermatol. 2021 Nov 5. pii: S0022-202X(21)02218.
PubMed Abstract available

DEL ROSSO M, Fibbi G, Laurenzana A, Margheri F, et al
A Possible Role for PAI-1 Blockade in Melanoma Immunotherapy.
J Invest Dermatol. 2021;141:2566-2568.
PubMed Abstract available

SUGAYA M
Treating Psoriasis with a Light Touch.
J Invest Dermatol. 2021;141:2564-2566.
PubMed Abstract available

ZHANG Z, Elder JT
Making Lemonade: Putting the Wisdom of the Genome to Work in Atopic Dermatitis.
J Invest Dermatol. 2021;141:2561-2564.
PubMed Abstract available

BOLLAG WB
Down-Regulated Calcium-Sensing Receptor in Keratinocytes and Skin from Aged Mice and Humans Impairs Function.
J Invest Dermatol. 2021;141:2558-2561.
PubMed Abstract available

BALMERT SC, Ghozloujeh ZG, Carey CD, Akilov OE, et al
Research Techniques Made Simple: Skin-Targeted Drug and Vaccine Delivery Using Dissolvable Microneedle Arrays.
J Invest Dermatol. 2021;141:2549-2557.
PubMed Abstract available

PATTERSON ROSA L, Walker N, Mallicote M, MacKay RJ, et al
Genomic Association of Chronic Idiopathic Anhidrosis to a Potassium Channel Subunit in a Large Animal Model.
J Invest Dermatol. 2021;141:2639-2645.
PubMed Abstract available

MURTHY S, Schilf P, Patzelt S, Thieme M, et al
Dapsone Suppresses Disease in Preclinical Murine Models of Pemphigoid Diseases.
J Invest Dermatol. 2021;141:2587-2595.
PubMed Abstract available

ZHAI S, Xu M, Li Q, Guo K, et al
Successful Treatment of Vitiligo with Cold Atmospheric PlasmaActivated Hydrogel.
J Invest Dermatol. 2021;141:2710-2719.
PubMed Abstract available

KINYO A, Kovacs AL, Degrell P, Kalman E, et al
Homozygous ITGA3 Missense Mutation in Adults in a Family with Syndromic Epidermolysis Bullosa (ILNEB) without Pulmonary Involvement.
J Invest Dermatol. 2021;141:2752-2756.
PubMed

AUGUSTO DG, de Almeida RC, Farias TDJ, Magalhaes WCS, et al
Unsuspected Associations of Variants within the Genes NOTCH4 and STEAP2-AS1 Uncovered by a GWAS in Endemic Pemphigus Foliaceus.
J Invest Dermatol. 2021;141:2741-2744.
PubMed

TAYEM R, Niemann C, Pesch M, Morgner J, et al
Laminin 332 Is Indispensable for Homeostatic Epidermal Differentiation Programs.
J Invest Dermatol. 2021;141:2602-2610.
PubMed Abstract available

CAO Y, Harvey BP, Hong F, Ruzek M, et al
Adalimumab Induces a Wound Healing Profile in Patients with Hidradenitis Suppurativa by Regulating Macrophage Differentiation and Matrix Metalloproteinase Expression.
J Invest Dermatol. 2021;141:2730-2740.
PubMed Abstract available

OLSEN CM, Pandeya N, Whiteman DC
International Increases in Merkel Cell Carcinoma Incidence Rates between 1997 and 2016.
J Invest Dermatol. 2021;141:2596-2601.
PubMed Abstract available

DAI X, Utsunomiya R, Shiraishi K, Mori H, et al
Nuclear IL-33 Plays an Important Role in the Suppression of FLG, LOR, Keratin 1, and Keratin 10 by IL-4 and IL-13 in Human Keratinocytes.
J Invest Dermatol. 2021;141:2646-2655.
PubMed Abstract available

October 2021

DZUNG A, Saltari A, Tiso N, Lyck R, et al
STK11 Prevents Invasion Through STAT3/5 and FAK Repression in Cutaneous Melanoma.
J Invest Dermatol. 2021 Oct 29. pii: S0022-202X(21)02466.
PubMed Abstract available

KLOPOT A, Baida G, Kel A, Tsoi LC, et al
Transcriptome analysis reveals intrinsic pro-inflammatory signaling in healthy African American skin.
J Invest Dermatol. 2021 Oct 29. pii: S0022-202X(21)02400.
PubMed Abstract available

KIM RH, Nomikou S, Coudray N, Jour G, et al
Deep learning and pathomics analyses reveal cell nuclei as important features for mutation prediction of BRAF-mutated melanomas.
J Invest Dermatol. 2021 Oct 29. pii: S0022-202X(21)02405.
PubMed Abstract available

PILKINGTON SM, Bulfone-Paus S, Griffiths CE, Watson RE, et al
Can skin aging contribute to systemic inflammaging?
J Invest Dermatol. 2021 Oct 28. pii: S0022-202X(21)02402.
PubMed

VIIKLEPP K, Nissinen L, Ojalill M, Riihila P, et al
C1r Upregulates Production of Matrix Metalloproteinase-13 and Promotes Invasion of Cutaneous Squamous Cell Carcinoma.
J Invest Dermatol. 2021 Oct 28. pii: S0022-202X(21)02379.
PubMed Abstract available

BRAEGELMANN C, Niebel D, Wenzel J
Targeted Therapies in Autoimmune Skin Diseases.
J Invest Dermatol. 2021 Oct 28. pii: S0022-202X(21)02287.
PubMed Abstract available

CROMPTON RA, Williams H, Campbell L, Lim HK, et al
An epidermal-specific role for arginase1 during cutaneous wound repair.
J Invest Dermatol. 2021 Oct 25. pii: S0022-202X(21)02288.
PubMed Abstract available

KIURU M, Kriner MA, Wong S, Zhu G, et al
High-plex spatial RNA profiling reveals cell type-specific biomarker expression during melanoma development.
J Invest Dermatol. 2021 Oct 23. pii: S0022-202X(21)02370.
PubMed Abstract available

RAMANI V, Chung JS, Ariizumi K, Cruz PD Jr, et al
Soluble DC-HIL/Gpnmb Modulates T-lymphocyte Extravasation to Inflamed Skin.
J Invest Dermatol. 2021 Oct 22. pii: S0022-202X(21)02349.
PubMed Abstract available

SENDIN-MARTIN M, Lara-Caro M, Harris U, Moronta M, et al
CLASSIFICATION OF BASAL CELL CARCINOMA IN EX VIVO CONFOCAL MICROSCOPY IMAGES FROM FRESHLY EXCISED TISSUES USING A DEEP LEARNING ALGORITHM.
J Invest Dermatol. 2021 Oct 22. pii: S0022-202X(21)02380.
PubMed Abstract available

AHMED F, Tseng HY, Ahn A, Gunatilake D, et al
Repurposing melanoma chemotherapy to activate inflammasomes in treatment of BRAF/MAPK inhibitor resistant melanoma.
J Invest Dermatol. 2021 Oct 22. pii: S0022-202X(21)02384.
PubMed Abstract available

AL RAHMOUN M, Ghiasvand R, Cairat M, Mahamat-Saleh Y, et al
Statin Use and Skin Cancer Risk: A Prospective Cohort Study.
J Invest Dermatol. 2021 Oct 22. pii: S0022-202X(21)02382.
PubMed Abstract available

KONG HH, Oh J
State of residency: microbial strain diversity in the skin.
J Invest Dermatol. 2021 Oct 21. pii: S0022-202X(21)02351.
PubMed Abstract available

NJAUW CN, Ji Z, Pham DM, Simoneau A, et al
Oncogenic KIT Induces Replication stress and Confers Cell Cycle Checkpoint Vulnerability in Melanoma.
J Invest Dermatol. 2021 Oct 20. pii: S0022-202X(21)02347.
PubMed Abstract available

JANDOVA J, Wondrak GT
Vemurafenib drives EMT gene expression in BRAFi-resistant BRAF(V600E)/NRAS(Q61K) melanoma enhancing tumor growth and metastasis in a bioluminescent murine model.
J Invest Dermatol. 2021 Oct 20. pii: S0022-202X(21)02368.
PubMed Abstract available

XUE K, Shao S, Fang H, Ma L, et al
Adipocyte-derived C1q-TNF-related Protein 3 Exhibits Anti-inflammatory effects via LAMP1-STAT3 axis in Psoriasis.
J Invest Dermatol. 2021 Oct 20. pii: S0022-202X(21)02369.
PubMed Abstract available

GARCIA-DIAZ N, Casar B, Alonso-Alonso R, Quevedo L, et al
PLCgamma1/PKCtheta Downstream Signaling Controls Cutaneous T-Cell Lymphoma Development And Progression.
J Invest Dermatol. 2021 Oct 20. pii: S0022-202X(21)02350.
PubMed Abstract available

NAGORE E, Viros A, Kumar R
Positive Attributes of Anti-TERT CD4 T-Helper Type 1 Immune Responses in Melanoma.
J Invest Dermatol. 2021 Oct 16. pii: S0022-202X(21)02269.
PubMed Abstract available

CHILIBROSTE S, Monaco A, Plata MC, Vola M, et al
Preclinical evaluation of LVR01 attenuated Salmonella as neoadjuvant intralesional therapy in combination with chemotherapy for melanoma treatment.
J Invest Dermatol. 2021 Oct 15. pii: S0022-202X(21)02317.
PubMed Abstract available

MARTINS C, Migayron L, Drullion C, Jacquemin C, et al
Vitiligo skin T cells are prone to produce type 1- and type 2-cytokines to induce melanocyte dysfunction and epidermal inflammatory response through JAK signaling.
J Invest Dermatol. 2021 Oct 13. pii: S0022-202X(21)02304.
PubMed Abstract available

SEO JY, You SW, Shin JG, Kim Y, et al
Genome-wide association study identifies multiple genetic loci for skin color in Korean women.
J Invest Dermatol. 2021 Oct 11. pii: S0022-202X(21)02303.
PubMed Abstract available

RAVIPATI A, Nolan S, Alphonse M, Dikeman D, et al
IL-6R/STAT3-signaling in keratinocytes rather than T cells induces psoriasis-like dermatitis in mice.
J Invest Dermatol. 2021 Oct 6. pii: S0022-202X(21)02291.
PubMed Abstract available

CASTILLO R, Subudhi I, Naik S
Fanning the Flames: IRAK2 Signaling in Differentiated Epithelium Potentiates Skin Inflammation.
J Invest Dermatol. 2021;141:2325-2327.
PubMed Abstract available

AZIN M, Demehri S
Innate Lymphoid Cells: New Targets for Cutaneous Squamous Cell Carcinoma Immunotherapy.
J Invest Dermatol. 2021;141:2320-2322.
PubMed Abstract available

YANG R, Wang RC
Research Techniques Made Simple: Studying Circular RNA in Skin Diseases.
J Invest Dermatol. 2021;141:2313-2319.
PubMed Abstract available

SIEBERT S, Sattar N
Estimating Cardiovascular Impacts of Drugs for Psoriatic Disease: A Long Way to Go.
J Invest Dermatol. 2021;141:2322-2325.
PubMed Abstract available

HASHIMOTO T, Mishra SK, Olivry T, Yosipovitch G, et al
Periostin, an Emerging Player in Itch Sensation.
J Invest Dermatol. 2021;141:2338-2343.
PubMed Abstract available

YAN D, Blauvelt A, Dey AK, Golpanian RS, et al
New Frontiers in Psoriatic Disease Research, Part II: Comorbidities and Targeted Therapies.
J Invest Dermatol. 2021;141:2328-2337.
PubMed Abstract available

SHAO S, Tsoi LC, Swindell WR, Chen J, et al
IRAK2 Has a Critical Role in Promoting Feed-Forward Amplification of Epidermal Inflammatory Responses.
J Invest Dermatol. 2021;141:2436-2448.
PubMed Abstract available

NORIMATSU Y, Yoshizaki A, Kabeya Y, Fukasawa T, et al
Expert-Level Distinction of Systemic Sclerosis from Hand Photographs Using Deep Convolutional Neural Networks.
J Invest Dermatol. 2021;141:2536-2539.
PubMed

WONGVIBULSIN S, Sutaria N, Williams KA, Huang AH, et al
A Nationwide Study of Prurigo Nodularis: Disease Burden and Healthcare Utilization in the United States.
J Invest Dermatol. 2021;141:2530-2533.
PubMed

CAO L, Yue X, Zhao Y, Du L, et al
Mechanisms of Broad-Band UVB IrradiationInduced Itch in Mice.
J Invest Dermatol. 2021;141:2499-2508.
PubMed Abstract available

September 2021

VAN HOVE L, Hoste E
Activation of fibroblasts in skin cancer.
J Invest Dermatol. 2021 Sep 30. pii: S0022-202X(21)02289.
PubMed Abstract available

CHHABRA G, Singh CK, Guzman-Perez G, Ndiaye MA, et al
Anti-melanoma effects of concomitant inhibition of SIRT1 and SIRT3 in Braf(V600E)/Pten(NULL) mice.
J Invest Dermatol. 2021 Sep 28. pii: S0022-202X(21)02223.
PubMed Abstract available

XU T, Dai J, Tang L, Yang L, et al
EZH2 inhibitor enhances the STING agonist-induced antitumor immunity in melanoma.
J Invest Dermatol. 2021 Sep 24. pii: S0022-202X(21)02227.
PubMed Abstract available

BEATTIE K, Jiang H, Gautam M, MacVittie MK, et al
TRPC3 Antagonizes Pruritus in A Mouse Contact Dermatitis Model.
J Invest Dermatol. 2021 Sep 24. pii: S0022-202X(21)02222.
PubMed Abstract available

WANG F, Luo Q, Chen Y, Liu Y, et al
A genome-wide scan on individual typology angle found variants at SLC24A2 associated with skin color variation in Chinese populations.
J Invest Dermatol. 2021 Sep 24. pii: S0022-202X(21)02226.
PubMed

MAURO TM
Ode to Salt: Commentary on "Skin Sodium Accumulates in Psoriasis and Reflects Disease Severity".
J Invest Dermatol. 2021 Sep 24. pii: S0022-202X(21)02174.
PubMed Abstract available

HAILFINGER S, Schulze-Osthoff K
Impaired Autophagy in Psoriasis and Atopic Dermatitis: A New Therapeutic Target?
J Invest Dermatol. 2021 Sep 23. pii: S0022-202X(21)01409.
PubMed Abstract available

GARZORZ-STARK N, Eyerich K
IFN-1s: Sentinels Shaping Distinct Immune Responses in Skin.
J Invest Dermatol. 2021 Sep 23. pii: S0022-202X(21)01668.
PubMed Abstract available

EMMONS MF, Smalley KSM
Ironing-Out the Details: New Strategies for Combining Ferroptosis Inhibitors with Immunotherapy in Melanoma.
J Invest Dermatol. 2021 Sep 23. pii: S0022-202X(21)01436.
PubMed Abstract available

ADELMANN CH, Rachmin I, Fisher DE
MFN2 Stabilization: A Bridge for Endoplasmic Reticulum Stress Sensitivity in Melanoma.
J Invest Dermatol. 2021 Sep 23. pii: S0022-202X(21)01224.
PubMed Abstract available

PANDIYAN P, McCormick TS
Regulation of IL-17A-Producing Cells in Skin Inflammatory Disorders.
J Invest Dermatol. 2021 Sep 21. pii: S0022-202X(21)01673.
PubMed Abstract available

ALLMEROTH K, Denzel MS
The RATIOnal Role of Polyamines in Epidermal Differentiation.
J Invest Dermatol. 2021;141:2105-2107.
PubMed Abstract available

YAN D, Gudjonsson JE, Le S, Maverakis E, et al
New Frontiers in Psoriatic Disease Research, Part I: Genetics, Environmental Triggers, Immunology, Pathophysiology, and Precision Medicine.
J Invest Dermatol. 2021;141:2112-2122.
PubMed Abstract available

NAVRAZHINA K, Garcet S, Gonzalez J, Grand D, et al
In-Depth Analysis of the Hidradenitis Suppurativa Serum Proteome Identifies Distinct Inflammatory Subtypes.
J Invest Dermatol. 2021;141:2197-2207.
PubMed Abstract available

MAHO-VAILLANT M, Perals C, Golinski ML, Hebert V, et al
Rituximab and Corticosteroid Effect on Desmoglein-Specific B Cells and Desmoglein-Specific T Follicular Helper Cells in Pemphigus.
J Invest Dermatol. 2021;141:2132-2140.
PubMed Abstract available

KOGA H, Teye K, Otsuji Y, Ishii N, et al
Autoantibodies to DSC3 in Pemphigus Exclusively Recognize Calcium-Dependent Epitope in Extracellular Domain 2.
J Invest Dermatol. 2021;141:2123-2131.
PubMed Abstract available

HABAULT J, Thonnart N, Pasquereau-Kotula E, Bagot M, et al
PAK1-Dependent Antitumor Effect of AAC-11Derived Peptides on Sezary Syndrome Malignant CD4(+) T Lymphocytes.
J Invest Dermatol. 2021;141:2261-2271.
PubMed Abstract available

ZOU Y, Yuan H, Zhou S, Zhou Y, et al
The Pathogenic Role of CD4(+) Tissue-Resident Memory T Cells Bearing T Follicular Helper-Like Phenotype in Pemphigus Lesions.
J Invest Dermatol. 2021;141:2141-2150.
PubMed Abstract available

August 2021

LAHMAN MC, Paulson KG, Nghiem PT, Chapuis AG, et al
Quality Is King: Fundamental Insights into Tumor Antigenicity from Virus-Associated Merkel Cell Carcinoma.
J Invest Dermatol. 2021;141:1897-1905.
PubMed Abstract available

VELLAICHAMY G, Dimitrion P, Zhou L, Ozog D, et al
Insights from gamma-Secretase: Functional Genetics of Hidradenitis Suppurativa.
J Invest Dermatol. 2021;141:1888-1896.
PubMed Abstract available

OTOTAKE Y, Yamaguchi Y, Asami M, Komitsu N, et al
Downregulated IRF8 in Monocytes and Macrophages of Patients with Systemic Sclerosis May Aggravate the Fibrotic Phenotype.
J Invest Dermatol. 2021;141:1954-1963.
PubMed Abstract available

LIAO WT, Hung CH, Liang SS, Yu S, et al
Anti-Inflammatory Effects Induced by Near-Infrared Light Irradiation through M2 Macrophage Polarization.
J Invest Dermatol. 2021;141:2056-2066.
PubMed Abstract available

SONG Z, Chen X, Zhao Q, Stanic V, et al
Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes.
J Invest Dermatol. 2021;141:1964-1974.
PubMed Abstract available

CHEN KL, Patel J, Zeidi M, Wysocka M, et al
Myeloid Dendritic Cells Are Major Producers of IFN-beta in Dermatomyositis and May Contribute to Hydroxychloroquine Refractoriness.
J Invest Dermatol. 2021;141:1906-1914.
PubMed Abstract available

SHI C, Ray-Jones H, Ding J, Duffus K, et al
Chromatin Looping Links Target Genes with Genetic Risk Loci for Dermatological Traits.
J Invest Dermatol. 2021;141:1975-1984.
PubMed Abstract available

SAMRA EB, Mahe YF, Le Balch M, Cavusoglu N, et al
Transcriptome Profiling of Pilosebaceous Units in Male Androgenetic Alopecia Reveals Altered Junctional Networks.
J Invest Dermatol. 2021;141:2070-2073.
PubMed

July 2021

HEDBERG M, Seykora JT
Clarifying Progress on the Genomic Landscape of Actinic Keratosis.
J Invest Dermatol. 2021;141:1622-1624.
PubMed Abstract available

SCHILF P, Schmitz M, Derenda-Hell A, Thieme M, et al
Inhibition of Glucose Metabolism Abrogates the Effector Phase of Bullous Pemphigoid-Like Epidermolysis Bullosa Acquisita.
J Invest Dermatol. 2021;141:1646-1655.
PubMed Abstract available

WIENHOLTZ NKF, Christensen CE, Coskun H, Zhang DG, et al
Infusion of Pituitary Adenylate Cyclase-Activating Polypeptide-38 in Patients with Rosacea Induces Flushing and Facial Edema that Can Be Attenuated by Sumatriptan.
J Invest Dermatol. 2021;141:1687-1698.
PubMed Abstract available

GRAVEMEYER J, Lange A, Ritter C, Spassova I, et al
Classical and Variant Merkel Cell Carcinoma Cell Lines Display Different Degrees of Neuroendocrine Differentiation and Epithelial-Mesenchymal Transition.
J Invest Dermatol. 2021;141:1675-1686.
PubMed Abstract available

SENESCHAL J, Duplaine A, Maillard H, Passeron T, et al
Efficacy and Safety of Tacrolimus 0.1% for the Treatment of Facial Vitiligo: A Multicenter Randomized, Double-Blinded, Vehicle-Controlled Study.
J Invest Dermatol. 2021;141:1728-1734.
PubMed Abstract available

LIPOVSKY A, Slivka PF, Su Z, Wang Y, et al
ACT1 Is Required for Murine IL-23-Induced Psoriasiform Inflammation Potentially Independent of E3 Ligase Activity.
J Invest Dermatol. 2021;141:1772-1779.
PubMed Abstract available

ZHU Y, Mitra N, Feng Y, Tishkoff S, et al
FLG Variation Differs between European Americans and African Americans.
J Invest Dermatol. 2021;141:1855-1857.
PubMed

LYUBCHENKO T, Collins HK, Vang KA, Leung DYM, et al
SMOC1 and IL-4 and IL-13 Cytokines Interfere with Ca(2+) Mobilization in Primary Human Keratinocytes.
J Invest Dermatol. 2021;141:1792-1801.
PubMed Abstract available

THOMSON J, Bewicke-Copley F, Anene CA, Gulati A, et al
The Genomic Landscape of Actinic Keratosis.
J Invest Dermatol. 2021;141:1664-1674.
PubMed Abstract available

SOLA-ORTIGOSA J, Munoz-Santos C, Otzet-Gramunt I, Masat-Tico T, et al
The Usefulness of Teledermatology in Monitoring the Efficacy and Safety of a Topical Treatment for Actinic Keratosis.
J Invest Dermatol. 2021;141:1837-1839.
PubMed

HOJMAN L, Cabrera R, Karsulovic C, Tempio F, et al
The Role of CXCL10 and IL-18 as Markers of Repigmentation Response in Nonsegmental Vitiligo Treated with Narrowband UVB Phototherapy: A Prospective Cohort Study.
J Invest Dermatol. 2021;141:1833-1836.
PubMed

CHO SI, Yu DA, Kim SI, Lee SM, et al
Pregnancy Outcomes in Female Patients with Alopecia Areata: A Nationwide Population-Based Study.
J Invest Dermatol. 2021;141:1844-1847.
PubMed

YOUSSEFIAN L, Niaziorimi F, Saeidian AH, South AP, et al
Knockdown of SDR9C7 Impairs Epidermal Barrier Function.
J Invest Dermatol. 2021;141:1754-1764.
PubMed Abstract available

YU Q, Parajuli N, Yi Q, Mishina Y, et al
ALK3 Is Not Required for the Embryonic Development, Homeostasis, and Repopulation of Epidermal Langerhans Cells in Steady and Inflammatory States.
J Invest Dermatol. 2021;141:1858-1861.
PubMed

June 2021

MURASE C, Takeichi T, Nomura T, Ogi T, et al
Hereditary Mucoepithelial Dysplasia and Autosomal-Dominant IFAP Syndrome Is a Clinical Spectrum Due to SREBF1 Variants.
J Invest Dermatol. 2021;141:1596-1598.
PubMed

SHI H, Smits JPH, van den Bogaard EH, Brewer MG, et al
Research Techniques Made Simple: Delivery of the CRISPR/Cas9 Components into Epidermal Cells.
J Invest Dermatol. 2021;141:1375-1381.
PubMed Abstract available

AKASAKA E, Kleiser S, Sengle G, Bruckner-Tuderman L, et al
Diversity of Mechanisms Underlying Latent TGF-beta Activation in Recessive Dystrophic Epidermolysis Bullosa.
J Invest Dermatol. 2021;141:1450-1460.
PubMed Abstract available

TAN MWY, Tan WR, Kong ZQ, Toh JH, et al
High Glucose Restraint of Acetylcholine-Induced Keratinocyte Epithelial-Mesenchymal Transition Is Mitigated by p38 Inhibition.
J Invest Dermatol. 2021;141:1438-1449.
PubMed Abstract available

ZHAO J, Yang S, Shu B, Chen L, et al
Transient High Glucose Causes Persistent Vascular Dysfunction and Delayed Wound Healing by the DNMT1-Mediated Ang-1/NF-kappaB Pathway.
J Invest Dermatol. 2021;141:1573-1584.
PubMed Abstract available

WU KY, Kim S, Liu VM, Sabino A, et al
Function-Blocking RHAMM Peptides Attenuate Fibrosis and Promote Antifibrotic Adipokines in a Bleomycin-Induced Murine Model of Systemic Sclerosis.
J Invest Dermatol. 2021;141:1482-1492.
PubMed Abstract available

BIENZ MN, Petrogiannis-Haliotis T, Pehr K, Benlimame N, et al
Three-Dimensional Telomeric Fingerprint of Mycosis Fungoides and/or Sezary Syndrome: A Pilot Study.
J Invest Dermatol. 2021;141:1598-1601.
PubMed

KOBAYASHI K, Kamekura R, Kato J, Kamiya S, et al
Cigarette Smoke Underlies the Pathogenesis of Palmoplantar Pustulosis via an IL-17A-Induced Production of IL-36gamma in Tonsillar Epithelial Cells.
J Invest Dermatol. 2021;141:1533-1541.
PubMed Abstract available

DE GROOT R, Bosma AL, Cornet R, Spuls PI, et al
The Selection Process for a Web-Based Application to Measure Patient-Reported Outcomes Following the Example of the TREAT NL Registry.
J Invest Dermatol. 2021;141:1592-1595.
PubMed

May 2021

NOE MH
Understanding Epidermal Necrolysis after the Initial Hospitalization.
J Invest Dermatol. 2021;141:1139-1140.
PubMed Abstract available

KIRBY JS
Unraveling the Heterogeneity of Hidradenitis Suppurativa with Phenotype Schema.
J Invest Dermatol. 2021;141:1136-1138.
PubMed Abstract available

LUO H, Faghankhani M, Cao Y, Uitto J, et al
Molecular Genetics and Modifier Genes in Pseudoxanthoma Elasticum, a Heritable Multisystem Ectopic Mineralization Disorder.
J Invest Dermatol. 2021;141:1148-1156.
PubMed Abstract available

BOURSIER G, Piram M, Rittore C, Sarrabay G, et al
Phenotypic Associations of PSTPIP1 Sequence Variants in PSTPIP1-Associated Autoinflammatory Diseases.
J Invest Dermatol. 2021;141:1141-1147.
PubMed Abstract available

YAO Q, Epstein CB, Banskota S, Issner R, et al
Epigenetic Alterations in Keratinocyte Carcinoma.
J Invest Dermatol. 2021;141:1207-1218.
PubMed Abstract available

CAZZANIGA S, Pezzolo E, Bettoli V, Abeni D, et al
Characterization of Hidradenitis Suppurativa Phenotypes: A Multidimensional Latent Class Analysis of the National Italian Registry IRHIS.
J Invest Dermatol. 2021;141:1236-1242.
PubMed Abstract available

WANG Z, Yoo YJ, De La Torre R, Topham C, et al
Inverse Correlation of TRIM32 and Protein Kinase C zeta in T Helper Type 2-Biased Inflammation.
J Invest Dermatol. 2021;141:1297-1307.
PubMed Abstract available

PU W, Wu W, Liu Q, Ma Y, et al
Exome-Wide Association Analysis Suggests LRP2BP as a Susceptibility Gene for Endothelial Injury in Systemic Sclerosis in the Han Chinese Population.
J Invest Dermatol. 2021;141:1254-1263.
PubMed Abstract available

MAKITA E, Matsuzaki Y, Fukui T, Matsui A, et al
Autoantibodies to BPAG1e Trigger Experimental Bullous Pemphigoid in Mice.
J Invest Dermatol. 2021;141:1167-1176.
PubMed Abstract available

April 2021

OKAMURA K, Garber M, Harris JE
Gaining Insight into Vitiligo Genetics through the Lens of a Large Epidemiologic Study.
J Invest Dermatol. 2021;141:718-721.
PubMed Abstract available

VEENSTRA J, Dimitrion P, Yao Y, Zhou L, et al
Research Techniques Made Simple: Use of Imaging Mass Cytometry for Dermatological Research and Clinical Applications.
J Invest Dermatol. 2021;141:705-712.
PubMed Abstract available

CHAO-CHU J, Murtough S, Zaman N, Pennington DJ, et al
iRHOM2: A Regulator of Palmoplantar Biology, Inflammation, and Viral Susceptibility.
J Invest Dermatol. 2021;141:722-726.
PubMed Abstract available

JACKOW J, Rami A, Hayashi R, Hansen C, et al
Targeting the Jak/Signal Transducer and Activator of Transcription 3 Pathway with Ruxolitinib in a Mouse Model of Recessive Dystrophic Epidermolysis Bullosa-Squamous Cell Carcinoma.
J Invest Dermatol. 2021;141:942-946.
PubMed

LIU X, Wang Y, Tao T, Zeng L, et al
GRPR/Extracellular Signal-Regulated Kinase and NPRA/Extracellular Signal-Regulated Kinase Signaling Pathways Play a Critical Role in Spinal Transmission of Chronic Itch.
J Invest Dermatol. 2021;141:863-873.
PubMed Abstract available

BRAUWEILER AM, Leung DYM, Goleva E
The Transcription Factor p63 Is a Direct Effector of IL-4- and IL-13-Mediated Repression of Keratinocyte Differentiation.
J Invest Dermatol. 2021;141:770-778.
PubMed Abstract available

SONG L, Bretz AC, Gravemeyer J, Spassova I, et al
The HDAC Inhibitor Domatinostat Promotes Cell-Cycle Arrest, Induces Apoptosis, and Increases Immunogenicity of Merkel Cell Carcinoma Cells.
J Invest Dermatol. 2021;141:903-912.
PubMed Abstract available

SRIVASTAVA RK, Khan J, Arumugam A, Muzaffar S, et al
5'-CapDependent Translation as a Potent Therapeutic Target for Lethal Human Squamous Cell Carcinoma.
J Invest Dermatol. 2021;141:742-753.
PubMed Abstract available

DELYON J, Porcher R, Battistella M, Meyer N, et al
A Multicenter Phase II Study of Pazopanib in Patients with Unresectable Dermatofibrosarcoma Protuberans.
J Invest Dermatol. 2021;141:761-769.
PubMed Abstract available

GILCHREST BA
Actinic Keratoses: Reconciling the Biology of Field Cancerization with Treatment Paradigms.
J Invest Dermatol. 2021;141:727-731.
PubMed Abstract available

YANG C, Ruiz-Rosado JD, Robledo-Avila FH, Li Z, et al
Antibody-Mediated Protection against Staphylococcus aureus Dermonecrosis: Synergy of Toxin Neutralization and Neutrophil Recruitment.
J Invest Dermatol. 2021;141:810-820.
PubMed Abstract available

BORNERT O, Hogervorst M, Nauroy P, Bischof J, et al
QR-313, an Antisense Oligonucleotide, Shows Therapeutic Efficacy for Treatment of Dominant and Recessive Dystrophic Epidermolysis Bullosa: A Preclinical Study.
J Invest Dermatol. 2021;141:883-893.
PubMed Abstract available

LUKAS D, Dietze-Schwonberg K, Kautz-Neu K, Lorenz B, et al
Induction of Regulatory T Cells in Leishmania majorInfected BALB/c Mice Does Not Require Langerin+ Dendritic Cells.
J Invest Dermatol. 2021;141:936-938.
PubMed

HARDEN JL, Shih YH, Xu J, Li R, et al
Paired Transcriptomic and Proteomic Analysis Implicates IL-1beta in the Pathogenesis of Papulopustular Rosacea Explants.
J Invest Dermatol. 2021;141:800-809.
PubMed Abstract available

LE DUFF F, Bouaziz JD, Fontas E, Ticchioni M, et al
Low-Dose IL-2 for Treating Moderate to Severe Alopecia Areata: A 52-Week Multicenter Prospective Placebo-Controlled Study Assessing its Impact on T Regulatory Cell and NK Cell Populations.
J Invest Dermatol. 2021;141:933-936.
PubMed

WHANG KA, Khanna R, Williams KA, Mahadevan V, et al
Health-Related QOL and Economic Burden of Chronic Pruritus.
J Invest Dermatol. 2021;141:754-760.
PubMed Abstract available

DU-HARPUR X, Arthurs C, Ganier C, Woolf R, et al
Clinically Relevant Vulnerabilities of Deep Machine Learning Systems for Skin Cancer Diagnosis.
J Invest Dermatol. 2021;141:916-920.
PubMed

SANNA M, Li X, Visconti A, Freidin MB, et al
Looking for Sunshine: Genetic Predisposition to Sun Seeking in 265,000 Individuals of European Ancestry.
J Invest Dermatol. 2021;141:779-786.
PubMed Abstract available

AHMAD S, Riddle AO, Sayed CJ
Outcomes of Routine Diabetes Screening for Patients with Hidradenitis Suppurativa.
J Invest Dermatol. 2021;141:927-930.
PubMed

PENG W, Kwiek B, Yu C, Garbi N, et al
Infiltration and Clustering of Major Histocompatibility Complex II(+) Antigen-Presenting Cells in the Skin of Patients with Atopic Dermatitis.
J Invest Dermatol. 2021;141:939-942.
PubMed

KIM HJ, Ahn HS, Kazmi SZ, Kang T, et al
Familial Risk of Vitiligo among First-Degree Relatives and Spouses: A Population-Based Cohort Study in Korea.
J Invest Dermatol. 2021;141:921-924.
PubMed

CHEN J, Zhu Z, Li Q, Lin Y, et al
Neutrophils Enhance Cutaneous Vascular Dilation and Permeability to Aggravate Psoriasis by Releasing Matrix Metallopeptidase 9.
J Invest Dermatol. 2021;141:787-799.
PubMed Abstract available

RAMOVS V, Krotenberg Garcia A, Kreft M, Sonnenberg A, et al
Integrin alpha3beta1 Is a Key Regulator of Several Protumorigenic Pathways during Skin Carcinogenesis.
J Invest Dermatol. 2021;141:732-741.
PubMed Abstract available

PERSA OD, Koester J, Niessen CM
Regulation of Cell Polarity and Tissue Architecture in Epidermal Aging and Cancer.
J Invest Dermatol. 2021;141.
PubMed Abstract available

RIZZA ERH, DiGiovanna JJ, Khan SG, Tamura D, et al
Xeroderma Pigmentosum: A Model for Human Premature Aging.
J Invest Dermatol. 2021;141.
PubMed Abstract available

March 2021

ZHAO Q, Almutairi M, Tailor A, Lister A, et al
HLA Class II-restricted CD8+ T cells contribute to the promiscuous immune response in dapsone hypersensitive patients.
J Invest Dermatol. 2021 Mar 30. pii: S0022-202X(21)01125.
PubMed Abstract available

NADERI-AZAD S, Croitoru D, Khalili S, Eder L, et al
Research Techniques Made Simple: Experimental Methodology for Imaging Mass Cytometry.
J Invest Dermatol. 2021;141:467-473.
PubMed Abstract available

QUAGLINO P, Fava P, Pileri A, Grandi V, et al
Phenotypical Markers, Molecular Mutations, and Immune Microenvironment as Targets for New Treatments in Patients with Mycosis Fungoides and/or Sezary Syndrome.
J Invest Dermatol. 2021;141:484-495.
PubMed Abstract available

THOMAS J, Wang R, Batra R, Bohner A, et al
CD23 Levels on B Cells Determine Long-Term Therapeutic Response in Patients with Atopic Eczema Treated with Selective IgE Immune Apheresis.
J Invest Dermatol. 2021;141:681-685.
PubMed

LI D, Peng H, Qu L, Sommar P, et al
miR-19a/b and miR-20a Promote Wound Healing by Regulating the Inflammatory Response of Keratinocytes.
J Invest Dermatol. 2021;141:659-671.
PubMed Abstract available

HART PH, Norval M
The Multiple Roles of Urocanic Acid in Health and Disease.
J Invest Dermatol. 2021;141:496-502.
PubMed Abstract available

VERMA D, Fekri SZ, Sigurdardottir G, Bivik Eding C, et al
Enhanced Inflammasome Activity in Patients with Psoriasis Promotes Systemic Inflammation.
J Invest Dermatol. 2021;141:586-595.
PubMed Abstract available

BARE Y, Chan GK, Hayday T, McGrath JA, et al
Slac2-b Coordinates Extracellular Vesicle Secretion to Regulate Keratinocyte Adhesion and Migration.
J Invest Dermatol. 2021;141:523-532.
PubMed Abstract available

KELEL M, Yang RB, Tsai TF, Liang PH, et al
FUT8 Remodeling of EGFR Regulates Epidermal Keratinocyte Proliferation during Psoriasis Development.
J Invest Dermatol. 2021;141:512-522.
PubMed Abstract available

ZENG F, Chen H, Chen L, Mao J, et al
An Autocrine Circuit of IL-33 in Keratinocytes Is Involved in the Progression of Psoriasis.
J Invest Dermatol. 2021;141:596-606.
PubMed Abstract available

SHIN JG, Leem S, Kim B, Kim Y, et al
GWAS Analysis of 17,019 Korean Women Identifies the Variants Associated with Facial Pigmented Spots.
J Invest Dermatol. 2021;141:555-562.
PubMed Abstract available

LO YH, Li CS, Chen HL, Chiang CY, et al
Galectin-8 Is Upregulated in Keratinocytes by IL-17A and Promotes Proliferation by Regulating Mitosis in Psoriasis.
J Invest Dermatol. 2021;141:503-511.
PubMed Abstract available

GOLDSTEIN NB, Steel A, Barbulescu CC, Koster MI, et al
Melanocyte Precursors in the Hair Follicle Bulge of Repigmented Vitiligo Skin Are Controlled by RHO-GTPase, KCTD10, and CTNNB1 Signaling.
J Invest Dermatol. 2021;141:638-647.
PubMed Abstract available

L'HERONDELLE K, Pierre O, Fouyet S, Leschiera R, et al
PAR2, Keratinocytes, and Cathepsin S Mediate the Sensory Effects of Ciguatoxins Responsible for Ciguatera Poisoning.
J Invest Dermatol. 2021;141:648-658.
PubMed Abstract available

STARK MS, Tell-Marti G, Martins da Silva V, Martinez-Barrios E, et al
The Distinctive Genomic Landscape of Giant Congenital Melanocytic Nevi.
J Invest Dermatol. 2021;141:692-695.
PubMed

LIU K, Luo J, Ma T, Fang M, et al
Germline Mutation of PLCD1 Contributes to Human Multiple Pilomatricomas through Protein Kinase D/Extracellular Signal-Regulated Kinase1/2 Cascade and TRPV6.
J Invest Dermatol. 2021;141:533-544.
PubMed Abstract available

ZHONG W, Hu L, Cao X, Zhao J, et al
GenotypePhenotype Correlation of TRPV3-Related Olmsted Syndrome.
J Invest Dermatol. 2021;141:545-554.
PubMed Abstract available

ARONOVICH A, Moyal L, Gorovitz B, Amitay-Laish I, et al
Cancer-Associated Fibroblasts in Mycosis Fungoides Promote Tumor Cell Migration and Drug Resistance through CXCL12/CXCR4.
J Invest Dermatol. 2021;141:619-627.
PubMed Abstract available

OKTEM A, Horzum U, Ertop P, Kundakci N, et al
Clinical Relevance of Polymorphonuclear Myeloid-Derived Suppressor Cells in Autoimmune-Blistering Disorders Pemphigus Vulgaris and Bullous Pemphigoid.
J Invest Dermatol. 2021;141:672-675.
PubMed

GAO Y, Liu F, Sun J, Wen Y, et al
Differential SATB1 Expression Reveals Heterogeneity of Cutaneous T-Cell Lymphoma.
J Invest Dermatol. 2021;141:607-618.
PubMed Abstract available

SHTESSEL M, Limjunyawong N, Oliver ET, Chichester K, et al
MRGPRX2 Activation Causes Increased Skin Reactivity in Patients with Chronic Spontaneous Urticaria.
J Invest Dermatol. 2021;141:678-681.
PubMed

NOVAIS FO, Nguyen BT, Scott P
Granzyme B Inhibition by Tofacitinib Blocks the Pathology Induced by CD8 T Cells in Cutaneous Leishmaniasis.
J Invest Dermatol. 2021;141:575-585.
PubMed Abstract available

JIANG M, Fang H, Dang E, Zhang J, et al
Small Extracellular Vesicles Containing miR-381-3p from Keratinocytes Promote T Helper Type 1 and T Helper Type 17 Polarization in Psoriasis.
J Invest Dermatol. 2021;141:563-574.
PubMed Abstract available

February 2021

BERNA R, Mitra N, Lou C, Wan J, et al
TSLP and IL-7R Variants Are Associated with Persistent Atopic Dermatitis.
J Invest Dermatol. 2021;141:446-450.
PubMed

FEIZPOUR A, Marstrand T, Bastholm L, Eirefelt S, et al
Label-Free Quantification of Pharmacokinetics in Skin with Stimulated Raman Scattering Microscopy and Deep Learning.
J Invest Dermatol. 2021;141:395-403.
PubMed Abstract available

JACKSON WD, Gulino A, Fossati-Jimack L, Castro Seoane R, et al
C3 Drives Inflammatory Skin Carcinogenesis Independently of C5.
J Invest Dermatol. 2021;141:404-414.
PubMed Abstract available

DIETZE-SCHWONBERG K, Lorenz B, Hartmann AK, Stassen M, et al
Mast Cell Deficiency Protects Susceptible BALB/c Mice from Progressive Murine Cutaneous Leishmaniasis.
J Invest Dermatol. 2021;141:450-453.
PubMed

HAO L, Park J, Jang HY, Bae EJ, et al
Inhibiting Protein Kinase Activity of Pyruvate Kinase M2 by SIRT2 Deacetylase Attenuates Psoriasis.
J Invest Dermatol. 2021;141:355-363.
PubMed Abstract available

CLAUDER AK, Kordowski A, Bartsch YC, Kohl G, et al
IgG Fc N-Glycosylation Translates MHCII Haplotype into Autoimmune Skin Disease.
J Invest Dermatol. 2021;141:285-294.
PubMed Abstract available

ZHENG Q, Capell BC, Parekh V, O'Day C, et al
Whole-Exome and Transcriptome Analysis of UV-Exposed Epidermis and Carcinoma In Situ Reveals Early Drivers of Carcinogenesis.
J Invest Dermatol. 2021;141:295-307.
PubMed Abstract available

KOGUCHI-YOSHIOKA H, Watanabe R, Matsumura Y, Okiyama N, et al
The Possible Linkage of Granzyme B-Producing Skin T Cells with the Disease Prognosis of Alopecia Areata.
J Invest Dermatol. 2021;141:427-429.
PubMed

GARSHICK MS, Baumer Y, Dey AK, Grattan R, et al
Characterization of PCSK9 in the Blood and Skin of Psoriasis.
J Invest Dermatol. 2021;141:308-315.
PubMed Abstract available

WU CH, Yang CY, Wang L, Gao HX, et al
Cutaneous T-Cell Lymphoma PDX Drug Screening Platform Identifies Cooperation between Inhibitions of PI3Kalpha/delta and HDAC.
J Invest Dermatol. 2021;141:364-373.
PubMed Abstract available

MIRANDA E, Roberts J, Novick S, Lapointe JM, et al
Immunohistochemical Characterization of the IL-13:IL-4 Receptor alpha Axis in the Skin of Adult Patients with Moderate to Severe Atopic Dermatitis and Healthy Controls.
J Invest Dermatol. 2021;141:440-443.
PubMed

January 2021

STONE RC, Aviv A, Paus R
Telomere Dynamics and Telomerase in the Biology of Hair Follicles and their Stem Cells as a Model for Aging Research.
J Invest Dermatol. 2021 Jan 25. pii: S0022-202X(20)32399.
PubMed Abstract available

November 2020

SAITO A, Ichimura Y, Kubota N, Tanaka R, et al
Interferon-gamma-stimulated apoptotic keratinocytes promote sclerodermatous changes in chronic graft-versus-host disease.
J Invest Dermatol. 2020 Nov 23. pii: S0022-202X(20)32290.
PubMed Abstract available

CASTILLO-GONZALEZ R, Cibrian D, Fernandez-Gallego N, Ramirez-Huesca M, et al
Galectin-1 expression in CD8(+) T lymphocytes controls inflammation in contact hypersensitivity.
J Invest Dermatol. 2020 Nov 9. pii: S0022-202X(20)32281.
PubMed Abstract available

WILKIE H, Janssen E, Leyva-Castillo JM, Geha RS, et al
DOCK8 expression in Treg cells maintains their stability and limits contact hypersensitivity.
J Invest Dermatol. 2020 Nov 7. pii: S0022-202X(20)32273.
PubMed Abstract available

October 2020

KUBOTA N, Saito A, Tanaka R, Nakamura Y, et al
Langerhans cells suppress CD8(+) T cells in situ during mucocutaneous acute graft-versus host disease.
J Invest Dermatol. 2020 Oct 19. pii: S0022-202X(20)32170.
PubMed Abstract available

September 2020

OLSEN CM, Pandeya N, Dusingize JC, Thompson BS, et al
Can people correctly assess their future risk of melanoma?
J Invest Dermatol. 2020 Sep 11. pii: S0022-202X(20)31964.
PubMed

ZHANG C, Smalley I, Emmons MF, Sharma R, et al
Non-canonical EphA2 signaling is a driver of tumor-endothelial cell interactions and metastatic dissemination in BRAF inhibitor resistant melanoma.
J Invest Dermatol. 2020 Sep 2. pii: S0022-202X(20)32047.
PubMed Abstract available

August 2020

SWAMINATHAN K, Campbell A, Papalazarou V, Jaber-Hijazi F, et al
The RAC1 target NCKAP1 plays a crucial role in progression of BRAF/PTEN -driven melanoma in mice.
J Invest Dermatol. 2020 Aug 7. pii: S0022-202X(20)31956.
PubMed Abstract available

July 2020

LE K, Matar H, Gupta M
Bromodomain epigenetic protein promotes metastatic potential in melanoma cells via increased invasiveness and decreased macrophage-mediated phagocytosis.
J Invest Dermatol. 2020 Jul 6. pii: S0022-202X(20)31733.
PubMed

XIONG H, Jiang M, Shao F, Ye H, et al
Risk and association of HLA alleles with methimazole-induced cutaneous adverse reactions in Chinese Han population.
J Invest Dermatol. 2020 Jul 1. pii: S0022-202X(20)31824.
PubMed

June 2020

WANG P, Li Y, Ma Y, Zhang X, et al
Comprehensive investigation into the role of ubiquitin conjugating enzyme E2S (UBE2S) in melanoma development.
J Invest Dermatol. 2020 Jun 27. pii: S0022-202X(20)31729.
PubMed Abstract available

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