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Articles published in Proc Natl Acad Sci U S A

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    February 2019
  1. SLEDGE GW
    Targeting CXCR4-induced desmoplasia to improve checkpoint inhibition in breast cancer.
    Proc Natl Acad Sci U S A. 2019 Feb 22. pii: 1900368116.
    PubMed     Text format    


    January 2019
  2. KOBOLD S
    Innate and adaptive immunity combined for cancer treatment.
    Proc Natl Acad Sci U S A. 2019;116:1087-1088.
    PubMed     Text format    


  3. HONG WD, Benayoud F, Nixon GL, Ford L, et al
    AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis.
    Proc Natl Acad Sci U S A. 2019;116:1414-1419.
    PubMed     Text format     Abstract available


  4. ZHANG S, Zhang H, Ghia EM, Huang J, et al
    Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody.
    Proc Natl Acad Sci U S A. 2019 Jan 8. pii: 1816262116.
    PubMed     Text format     Abstract available


    December 2018
  5. TOMINAGA K, Minato H, Murayama T, Sasahara A, et al
    Semaphorin signaling via MICAL3 induces symmetric cell division to expand breast cancer stem-like cells.
    Proc Natl Acad Sci U S A. 2018 Dec 26. pii: 1806851116.
    PubMed     Text format     Abstract available


  6. BOCCI F, Gearhart-Serna L, Boareto M, Ribeiro M, et al
    Toward understanding cancer stem cell heterogeneity in the tumor microenvironment.
    Proc Natl Acad Sci U S A. 2018 Dec 26. pii: 1815345116.
    PubMed     Text format     Abstract available


  7. TERAO C, Yoshifuji H, Matsumura T, Naruse TK, et al
    Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis.
    Proc Natl Acad Sci U S A. 2018;115:13045-13050.
    PubMed     Text format     Abstract available


  8. KAPLANOV I, Carmi Y, Kornetsky R, Shemesh A, et al
    Blocking IL-1beta reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation.
    Proc Natl Acad Sci U S A. 2018 Dec 13. pii: 1812266115.
    PubMed     Text format     Abstract available


  9. VOISIN T, Chiu IM
    Molecular link between itch and atopic dermatitis.
    Proc Natl Acad Sci U S A. 2018 Dec 11. pii: 1818879115.
    PubMed     Text format    


  10. TOKUYAMA M, Kong Y, Song E, Jayewickreme T, et al
    ERVmap analysis reveals genome-wide transcription of human endogenous retroviruses.
    Proc Natl Acad Sci U S A. 2018;115:12565-12572.
    PubMed     Text format     Abstract available


  11. LIU C, Sun L, Yang J, Liu T, et al
    FSIP1 regulates autophagy in breast cancer.
    Proc Natl Acad Sci U S A. 2018 Dec 3. pii: 1809681115.
    PubMed     Text format     Abstract available


    November 2018
  12. MATSUNUMA R, Chan DW, Kim BJ, Singh P, et al
    DPYSL3 modulates mitosis, migration, and epithelial-to-mesenchymal transition in claudin-low breast cancer.
    Proc Natl Acad Sci U S A. 2018 Nov 29. pii: 1810598115.
    PubMed     Text format     Abstract available


  13. EMRICK JJ, Mathur A, Wei J, Gracheva EO, et al
    Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch.
    Proc Natl Acad Sci U S A. 2018 Nov 21. pii: 1814132115.
    PubMed     Text format     Abstract available


    October 2018
  14. ABBASI I, Trancoso Lopo de Queiroz A, Kirstein OD, Nasereddin A, et al
    Plant-feeding phlebotomine sand flies, vectors of leishmaniasis, prefer Cannabis sativa.
    Proc Natl Acad Sci U S A. 2018 Oct 29. pii: 1810435115.
    PubMed     Text format     Abstract available


  15. SUN XX, Chen Y, Su Y, Wang X, et al
    SUMO protease SENP1 deSUMOylates and stabilizes c-Myc.
    Proc Natl Acad Sci U S A. 2018;115:10983-10988.
    PubMed     Text format     Abstract available


  16. LIANG W, Li Q, Ferrara N
    Metastatic growth instructed by neutrophil-derived transferrin.
    Proc Natl Acad Sci U S A. 2018;115:11060-11065.
    PubMed     Text format     Abstract available


  17. PLANTAMURA E, Dzutsev A, Chamaillard M, Djebali S, et al
    MAVS deficiency induces gut dysbiotic microbiota conferring a proallergic phenotype.
    Proc Natl Acad Sci U S A. 2018;115:10404-10409.
    PubMed     Text format     Abstract available


  18. CHAN LC, Rossetti M, Miller LS, Filler SG, et al
    Protective immunity in recurrent Staphylococcus aureus infection reflects localized immune signatures and macrophage-conferred memory.
    Proc Natl Acad Sci U S A. 2018 Oct 8. pii: 1808353115.
    PubMed     Text format     Abstract available


  19. MULLER A, Hennig A, Lorscheid S, Grondona P, et al
    IkappaBzeta is a key transcriptional regulator of IL-36-driven psoriasis-related gene expression in keratinocytes.
    Proc Natl Acad Sci U S A. 2018;115:10088-10093.
    PubMed     Text format     Abstract available


    September 2018
  20. REESE JM, Bruinsma ES, Nelson AW, Chernukhin I, et al
    ERbeta-mediated induction of cystatins results in suppression of TGFbeta signaling and inhibition of triple-negative breast cancer metastasis.
    Proc Natl Acad Sci U S A. 2018 Sep 26. pii: 1807751115.
    PubMed     Text format     Abstract available


  21. GURYEV EL, Volodina NO, Shilyagina NY, Gudkov SV, et al
    Radioactive ((90)Y) upconversion nanoparticles conjugated with recombinant targeted toxin for synergistic nanotheranostics of cancer.
    Proc Natl Acad Sci U S A. 2018;115:9690-9695.
    PubMed     Text format     Abstract available


  22. LAN J, Lu H, Samanta D, Salman S, et al
    Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment.
    Proc Natl Acad Sci U S A. 2018 Sep 21. pii: 1809695115.
    PubMed     Text format     Abstract available


  23. CHU B, He A, Tian Y, He W, et al
    Photoaffinity-engineered protein scaffold for systematically exploring native phosphotyrosine signaling complexes in tumor samples.
    Proc Natl Acad Sci U S A. 2018;115:E8863-E8872.
    PubMed     Text format     Abstract available


    August 2018
  24. ARVANITIS CD, Askoxylakis V, Guo Y, Datta M, et al
    Mechanisms of enhanced drug delivery in brain metastases with focused ultrasound-induced blood-tumor barrier disruption.
    Proc Natl Acad Sci U S A. 2018 Aug 27. pii: 1807105115.
    PubMed     Text format     Abstract available


  25. GISTELINCK C, Kwon RY, Malfait F, Symoens S, et al
    Zebrafish type I collagen mutants faithfully recapitulate human type I collagenopathies.
    Proc Natl Acad Sci U S A. 2018;115:E8037-E8046.
    PubMed     Text format     Abstract available


  26. GRITHER WR, Longmore GD
    Inhibition of tumor-microenvironment interaction and tumor invasion by small-molecule allosteric inhibitor of DDR2 extracellular domain.
    Proc Natl Acad Sci U S A. 2018;115:E7786-E7794.
    PubMed     Text format     Abstract available


  27. HANSEN AL, Buchan GJ, Ruhl M, Mukai K, et al
    Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling.
    Proc Natl Acad Sci U S A. 2018;115:E7768-E7775.
    PubMed     Text format     Abstract available


  28. SU Z, Song J, Wang Z, Zhou L, et al
    Tumor promoter TPA activates Wnt/beta-catenin signaling in a casein kinase 1-dependent manner.
    Proc Natl Acad Sci U S A. 2018;115:E7522-E7531.
    PubMed     Text format     Abstract available


  29. DATTA S, Misra SK, Saha ML, Lahiri N, et al
    Orthogonal self-assembly of an organoplatinum(II) metallacycle and cucurbit[8]uril that delivers curcumin to cancer cells.
    Proc Natl Acad Sci U S A. 2018;115:8087-8092.
    PubMed     Text format     Abstract available


  30. FOULDS CE
    Disrupting a negative feedback loop drives endocrine therapy-resistant breast cancer.
    Proc Natl Acad Sci U S A. 2018 Aug 6. pii: 1811263115.
    PubMed     Text format    


    July 2018
  31. REN C, Zhang G, Han F, Fu S, et al
    Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth.
    Proc Natl Acad Sci U S A. 2018;115:7949-7954.
    PubMed     Text format     Abstract available


  32. MUHLEMANN B, Margaryan A, Damgaard PB, Allentoft ME, et al
    Ancient human parvovirus B19 in Eurasia reveals its long-term association with humans.
    Proc Natl Acad Sci U S A. 2018;115:7557-7562.
    PubMed     Text format     Abstract available


  33. LINCOLN V, Cogan J, Hou Y, Hirsch M, et al
    Gentamicin induces LAMB3 nonsense mutation readthrough and restores functional laminin 332 in junctional epidermolysis bullosa.
    Proc Natl Acad Sci U S A. 2018;115:E6536-E6545.
    PubMed     Text format     Abstract available


  34. WANG B, Li D, Kovalchuk I, Apel IJ, et al
    miR-34a directly targets tRNAi(Met) precursors and affects cellular proliferation, cell cycle, and apoptosis.
    Proc Natl Acad Sci U S A. 2018;115:7392-7397.
    PubMed     Text format     Abstract available


  35. XIAO T, Li W, Wang X, Xu H, et al
    Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.
    Proc Natl Acad Sci U S A. 2018 Jul 9. pii: 1722617115.
    PubMed     Text format     Abstract available


  36. LEE JJ, van de Ven RAH, Zaganjor E, Ng MR, et al
    Inhibition of epithelial cell migration and Src/FAK signaling by SIRT3.
    Proc Natl Acad Sci U S A. 2018;115:7057-7062.
    PubMed     Text format     Abstract available


    June 2018
  37. BHATTACHARYA M, Berends ETM, Chan R, Schwab E, et al
    Staphylococcus aureus biofilms release leukocidins to elicit extracellular trap formation and evade neutrophil-mediated killing.
    Proc Natl Acad Sci U S A. 2018 Jun 25. pii: 1721949115.
    PubMed     Text format     Abstract available


  38. MARGULIS K, Chiou AS, Aasi SZ, Tibshirani RJ, et al
    Distinguishing malignant from benign microscopic skin lesions using desorption electrospray ionization mass spectrometry imaging.
    Proc Natl Acad Sci U S A. 2018;115:6347-6352.
    PubMed     Text format     Abstract available


  39. ZHANG Y, Hwang BJ, Liu Z, Li N, et al
    BP180 dysfunction triggers spontaneous skin inflammation in mice.
    Proc Natl Acad Sci U S A. 2018;115:6434-6439.
    PubMed     Text format     Abstract available


  40. MITTAL S, Yeh K, Leslie LS, Kenkel S, et al
    Simultaneous cancer and tumor microenvironment subtyping using confocal infrared microscopy for all-digital molecular histopathology.
    Proc Natl Acad Sci U S A. 2018;115:E5651-E5660.
    PubMed     Text format     Abstract available


  41. SUN X, Wang X, Tang Z, Grivainis M, et al
    Transcription factor profiling reveals molecular choreography and key regulators of human retrotransposon expression.
    Proc Natl Acad Sci U S A. 2018;115:E5526-E5535.
    PubMed     Text format     Abstract available


  42. ZHU Y, Cankova Z, Iwanaszko M, Lichtor S, et al
    Potent laminin-inspired antioxidant regenerative dressing accelerates wound healing in diabetes.
    Proc Natl Acad Sci U S A. 2018 Jun 11. pii: 1804262115.
    PubMed     Text format     Abstract available


  43. DE SEMIR D, Bezrookove V, Nosrati M, Dar AA, et al
    PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer.
    Proc Natl Acad Sci U S A. 2018 Jun 4. pii: 1804779115.
    PubMed     Text format     Abstract available


    May 2018
  44. ROY B, Venkatachalapathy S, Ratna P, Wang Y, et al
    Laterally confined growth of cells induces nuclear reprogramming in the absence of exogenous biochemical factors.
    Proc Natl Acad Sci U S A. 2018;115:E4741-E4750.
    PubMed     Text format     Abstract available


  45. SEO A, Steinberg-Shemer O, Unal S, Casadei S, et al
    Mechanism for survival of homozygous nonsense mutations in the tumor suppressor gene BRCA1.
    Proc Natl Acad Sci U S A. 2018;115:5241-5246.
    PubMed     Text format     Abstract available


  46. LAI X, Stiff A, Duggan M, Wesolowski R, et al
    Modeling combination therapy for breast cancer with BET and immune checkpoint inhibitors.
    Proc Natl Acad Sci U S A. 2018 May 7. pii: 1721559115.
    PubMed     Text format     Abstract available


    April 2018
  47. NAIR P, Vilcek J
    Profile of Alexander Y. Rudensky, winner of the 2018 Vilcek Prize in Biomedical Science.
    Proc Natl Acad Sci U S A. 2018;115:4301-4304.
    PubMed     Text format    


  48. BUNG N, Roy A, Chen B, Das D, et al
    Human hydroxymethylbilane synthase: Molecular dynamics of the pyrrole chain elongation identifies step-specific residues that cause AIP.
    Proc Natl Acad Sci U S A. 2018;115:E4071-E4080.
    PubMed     Text format     Abstract available


  49. VEGA-RUBIN-DE-CELIS S, Zou Z, Fernandez AF, Ci B, et al
    Increased autophagy blocks HER2-mediated breast tumorigenesis.
    Proc Natl Acad Sci U S A. 2018;115:4176-4181.
    PubMed     Text format     Abstract available


  50. ZHAO L, Huang S, Mei S, Yang Z, et al
    Pharmacological activation of estrogen receptor beta augments innate immunity to suppress cancer metastasis.
    Proc Natl Acad Sci U S A. 2018;115:E3673-E3681.
    PubMed     Text format     Abstract available


  51. LIU Y, Liu Y, Wu J, Roizman B, et al
    Innate responses to gene knockouts impact overlapping gene networks and vary with respect to resistance to viral infection.
    Proc Natl Acad Sci U S A. 2018;115:E3230-E3237.
    PubMed     Text format     Abstract available


    March 2018
  52. KE H, Zhao L, Zhang H, Feng X, et al
    Loss of TDP43 inhibits progression of triple-negative breast cancer in coordination with SRSF3.
    Proc Natl Acad Sci U S A. 2018 Mar 26. pii: 1714573115.
    PubMed     Text format     Abstract available


  53. FLOROS KV, Lochmann TL, Hu B, Monterrubio C, et al
    Coamplification of miR-4728 protects HER2-amplified breast cancers from targeted therapy.
    Proc Natl Acad Sci U S A. 2018;115:E2594-E2603.
    PubMed     Text format     Abstract available


  54. ROBICHAUD N, Hsu BE, Istomine R, Alvarez F, et al
    Translational control in the tumor microenvironment promotes lung metastasis: Phosphorylation of eIF4E in neutrophils.
    Proc Natl Acad Sci U S A. 2018;115:E2202-E2209.
    PubMed     Text format     Abstract available


    February 2018
  55. HASHIMOTO K, Ochi H, Sunamura S, Kosaka N, et al
    Cancer-secreted hsa-miR-940 induces an osteoblastic phenotype in the bone metastatic microenvironment via targeting ARHGAP1 and FAM134A.
    Proc Natl Acad Sci U S A. 2018;115:2204-2209.
    PubMed     Text format     Abstract available


  56. HONG X, Sullivan RJ, Kalinich M, Kwan TT, et al
    Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy.
    Proc Natl Acad Sci U S A. 2018 Feb 16. pii: 1719264115.
    PubMed     Text format     Abstract available


  57. STEWART MD, Zelin E, Dhall A, Walsh T, et al
    BARD1 is necessary for ubiquitylation of nucleosomal histone H2A and for transcriptional regulation of estrogen metabolism genes.
    Proc Natl Acad Sci U S A. 2018;115:1316-1321.
    PubMed     Text format     Abstract available


  58. MARTURANO-KRUIK A, Nava MM, Yeager K, Chramiec A, et al
    Human bone perivascular niche-on-a-chip for studying metastatic colonization.
    Proc Natl Acad Sci U S A. 2018;115:1256-1261.
    PubMed     Text format     Abstract available


    January 2018
  59. TAGGART D, Andreou T, Scott KJ, Williams J, et al
    Anti-PD-1/anti-CTLA-4 efficacy in melanoma brain metastases depends on extracranial disease and augmentation of CD8(+) T cell trafficking.
    Proc Natl Acad Sci U S A. 2018 Jan 31. pii: 1714089115.
    PubMed     Text format     Abstract available


  60. THU KL, Silvester J, Elliott MJ, Ba-Alawi W, et al
    Disruption of the anaphase-promoting complex confers resistance to TTK inhibitors in triple-negative breast cancer.
    Proc Natl Acad Sci U S A. 2018 Jan 29. pii: 1719577115.
    PubMed     Text format     Abstract available


  61. SAMANTA D, Park Y, Ni X, Li H, et al
    Chemotherapy induces enrichment of CD47(+)/CD73(+)/PDL1(+) immune evasive triple-negative breast cancer cells.
    Proc Natl Acad Sci U S A. 2018 Jan 24. pii: 1718197115.
    PubMed     Text format     Abstract available


  62. NYSTROM A, Bornert O, Kuhl T, Gretzmeier C, et al
    Impaired lymphoid extracellular matrix impedes antibacterial immunity in epidermolysis bullosa.
    Proc Natl Acad Sci U S A. 2018;115:E705-E714.
    PubMed     Text format     Abstract available


    December 2017
  63. DOHERTY MR, Cheon H, Junk DJ, Vinayak S, et al
    Interferon-beta represses cancer stem cell properties in triple-negative breast cancer.
    Proc Natl Acad Sci U S A. 2017 Dec 11. pii: 1713728114.
    PubMed     Text format     Abstract available


    November 2017
  64. BEAUSANG JF, Wheeler AJ, Chan NH, Hanft VR, et al
    T cell receptor sequencing of early-stage breast cancer tumors identifies altered clonal structure of the T cell repertoire.
    Proc Natl Acad Sci U S A. 2017 Nov 14. pii: 201713863.
    PubMed     Text format     Abstract available


    October 2017
  65. BASUDHAR D, Glynn SA, Greer M, Somasundaram V, et al
    Coexpression of NOS2 and COX2 accelerates tumor growth and reduces survival in estrogen receptor-negative breast cancer.
    Proc Natl Acad Sci U S A. 2017 Oct 27. pii: 201709119.
    PubMed     Text format     Abstract available


  66. SANSONE P, Savini C, Kurelac I, Chang Q, et al
    Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer.
    Proc Natl Acad Sci U S A. 2017;114:E9066-E9075.
    PubMed     Text format     Abstract available


    September 2017
  67. HE F, Chiou AE, Loh HC, Lynch M, et al
    Multiscale characterization of the mineral phase at skeletal sites of breast cancer metastasis.
    Proc Natl Acad Sci U S A. 2017 Sep 18. pii: 201708161.
    PubMed     Text format     Abstract available


    August 2017
  68. DUGGAN MC, Stiff AR, Bainazar M, Regan K, et al
    Identification of NRAS isoform 2 overexpression as a mechanism facilitating BRAF inhibitor resistance in malignant melanoma.
    Proc Natl Acad Sci U S A. 2017 Aug 21. pii: 201704371.
    PubMed     Text format     Abstract available


  69. CHANG YS, Jalgaonkar SP, Middleton JD, Hai T, et al
    Stress-inducible gene Atf3 in the noncancer host cells contributes to chemotherapy-exacerbated breast cancer metastasis.
    Proc Natl Acad Sci U S A. 2017 Aug 7. pii: 201700455.
    PubMed     Text format     Abstract available


    July 2017
  70. WRIGHT HJ, Hou J, Xu B, Cortez M, et al
    CDCP1 drives triple-negative breast cancer metastasis through reduction of lipid-droplet abundance and stimulation of fatty acid oxidation.
    Proc Natl Acad Sci U S A. 2017 Jul 24. pii: 201703791.
    PubMed     Text format     Abstract available


  71. LUNAVAT TR, Cheng L, Einarsdottir BO, Olofsson Bagge R, et al
    BRAFV600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells.
    Proc Natl Acad Sci U S A. 2017 Jul 6. pii: 201705206.
    PubMed     Text format     Abstract available


  72. LIU T, Zhang H, Sun L, Zhao D, et al
    FSIP1 binds HER2 directly to regulate breast cancer growth and invasiveness.
    Proc Natl Acad Sci U S A. 2017 Jul 3. pii: 201621486.
    PubMed     Text format     Abstract available


    June 2017
  73. CASCIELLO F, Al-Ejeh F, Kelly G, Brennan DJ, et al
    G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis.
    Proc Natl Acad Sci U S A. 2017 Jun 19. pii: 201618706.
    PubMed     Text format     Abstract available


    May 2017
  74. JESELSOHN R, Cornwell M, Pun M, Buchwalter G, et al
    Embryonic transcription factor SOX9 drives breast cancer endocrine resistance.
    Proc Natl Acad Sci U S A. 2017 May 15. pii: 201620993.
    PubMed     Text format     Abstract available


    April 2017
  75. ROSSI M, Castiglioni P, Hartley MA, Eren RO, et al
    Type I interferons induced by endogenous or exogenous viral infections promote metastasis and relapse of leishmaniasis.
    Proc Natl Acad Sci U S A. 2017 Apr 24. pii: 201621447.
    PubMed     Text format     Abstract available


    March 2017
  76. KOSTARNOY AV, Gancheva PG, Lepenies B, Tukhvatulin AI, et al
    Receptor Mincle promotes skin allergies and is capable of recognizing cholesterol sulfate.
    Proc Natl Acad Sci U S A. 2017 Mar 14. pii: 201611665.
    PubMed     Text format     Abstract available


  77. CHEN IH, Xue L, Hsu CC, Paez JS, et al
    Phosphoproteins in extracellular vesicles as candidate markers for breast cancer.
    Proc Natl Acad Sci U S A. 2017 Mar 7. pii: 201618088.
    PubMed     Text format     Abstract available


  78. BIERIE B, Pierce SE, Kroeger C, Stover DG, et al
    Integrin-beta4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells.
    Proc Natl Acad Sci U S A. 2017 Mar 7. pii: 201618298.
    PubMed     Text format     Abstract available


  79. SHAHI P, Wang CY, Lawson DA, Slorach EM, et al
    ZNF503/Zpo2 drives aggressive breast cancer progression by down-regulation of GATA3 expression.
    Proc Natl Acad Sci U S A. 2017 Mar 3. pii: 201701690.
    PubMed     Text format     Abstract available


  80. CHEN L, Jenjaroenpun P, Pillai AM, Ivshina AV, et al
    Transposon insertional mutagenesis in mice identifies human breast cancer susceptibility genes and signatures for stratification.
    Proc Natl Acad Sci U S A. 2017 Mar 1. pii: 201701512.
    PubMed     Text format     Abstract available


    February 2017
  81. TAVERA-MENDOZA LE, Westerling T, Libby E, Marusyk A, et al
    Vitamin D receptor regulates autophagy in the normal mammary gland and in luminal breast cancer cells.
    Proc Natl Acad Sci U S A. 2017 Feb 27. pii: 201615015.
    PubMed     Text format     Abstract available


  82. WIELAENDER F, Sarviaho R, James F, Hytonen MK, et al
    Generalized myoclonic epilepsy with photosensitivity in juvenile dogs caused by a defective DIRAS family GTPase 1.
    Proc Natl Acad Sci U S A. 2017 Feb 21. pii: 201614478.
    PubMed     Text format     Abstract available


    January 2017
  83. WU W, Lu Z, Li F, Wang W, et al
    Efficient in vivo gene editing using ribonucleoproteins in skin stem cells of recessive dystrophic epidermolysis bullosa mouse model.
    Proc Natl Acad Sci U S A. 2017 Jan 30. pii: 201614775.
    PubMed     Text format     Abstract available


  84. KUHLMANN FM, Robinson JI, Bluemling GR, Ronet C, et al
    Antiviral screening identifies adenosine analogs targeting the endogenous dsRNA Leishmania RNA virus 1 (LRV1) pathogenicity factor.
    Proc Natl Acad Sci U S A. 2017 Jan 17. pii: 201619114.
    PubMed     Text format     Abstract available


  85. MANDELL MA, Beverley SM
    Continual renewal and replication of persistent Leishmania major parasites in concomitantly immune hosts.
    Proc Natl Acad Sci U S A. 2017 Jan 17. pii: 201619265.
    PubMed     Text format     Abstract available


  86. CHEN P, Zuo H, Xiong H, Kolar MJ, et al
    Gpr132 sensing of lactate mediates tumor-macrophage interplay to promote breast cancer metastasis.
    Proc Natl Acad Sci U S A. 2017 Jan 3. pii: 201614035.
    PubMed     Text format     Abstract available


    November 2016
  87. LI Y, Cheng HS, Chng WJ, Tergaonkar V, et al
    Activation of mutant TERT promoter by RAS-ERK signaling is a key step in malignant progression of BRAF-mutant human melanomas.
    Proc Natl Acad Sci U S A. 2016 Nov 23. pii: 201611106.
    PubMed     Text format     Abstract available


  88. CRUSE G, Yin Y, Fukuyama T, Desai A, et al
    Exon skipping of FcepsilonRIbeta eliminates expression of the high-affinity IgE receptor in mast cells with therapeutic potential for allergy.
    Proc Natl Acad Sci U S A. 2016 Nov 21. pii: 201608520.
    PubMed     Text format     Abstract available


  89. RANGEL R, Lee SC, Hon-Kim Ban K, Guzman-Rojas L, et al
    Transposon mutagenesis identifies genes that cooperate with mutant Pten in breast cancer progression.
    Proc Natl Acad Sci U S A. 2016 Nov 14. pii: 201613859.
    PubMed     Text format     Abstract available


  90. DANILOVA L, Wang H, Sunshine J, Kaunitz GJ, et al
    Association of PD-1/PD-L axis expression with cytolytic activity, mutational load, and prognosis in melanoma and other solid tumors.
    Proc Natl Acad Sci U S A. 2016 Nov 11. pii: 201607836.
    PubMed     Text format     Abstract available


  91. SPRANGER S, Luke JJ, Bao R, Zha Y, et al
    Density of immunogenic antigens does not explain the presence or absence of the T-cell-inflamed tumor microenvironment in melanoma.
    Proc Natl Acad Sci U S A. 2016 Nov 11. pii: 201609376.
    PubMed     Text format     Abstract available


  92. LIU B, Tai Y, Achanta S, Kaelberer MM, et al
    IL-33/ST2 signaling excites sensory neurons and mediates itch response in a mouse model of poison ivy contact allergy.
    Proc Natl Acad Sci U S A. 2016 Nov 7. pii: 201606608.
    PubMed     Text format     Abstract available


  93. XU GJ, Shah AA, Li MZ, Xu Q, et al
    Systematic autoantigen analysis identifies a distinct subtype of scleroderma with coincident cancer.
    Proc Natl Acad Sci U S A. 2016 Nov 7. pii: 201615990.
    PubMed     Text format     Abstract available


    October 2016
  94. WANG Z, Li B, Zhou L, Yu S, et al
    Prodigiosin inhibits Wnt/beta-catenin signaling and exerts anticancer activity in breast cancer cells.
    Proc Natl Acad Sci U S A. 2016 Oct 31. pii: 201616336.
    PubMed     Text format     Abstract available


  95. FU X, Jeselsohn R, Pereira R, Hollingsworth EF, et al
    FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer.
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    September 2016
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