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Articles published in Blood

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Single Articles

    August 2022
  1. HOLMES ZC, Tang H, Liu C, Bush AT, et al
    Prebiotic galactooligosaccharides interact with mouse gut microbiota to attenuate acute graft-versus-host disease.
    Blood. 2022 Aug 5. pii: 486126. doi: 10.1182/blood.2021015178.

  2. MAO X, Li L
    p57Kip2 indirectly regulates AGM HSCs.
    Blood. 2022;140:411-412.

    July 2022
  3. LI C, Wu B, Li Y, Liu Y, et al
    Loss of sphingosine kinase 2 promotes the expansion of hematopoietic stem cells by improving their metabolic fitness.
    Blood. 2022 Jul 26. pii: 486023. doi: 10.1182/blood.2022016112.
    PubMed     Abstract available

  4. KULL T, Wehling A, Etzrodt M, Auler M, et al
    NfkappaB signaling dynamics and their target genes differ between mouse blood cell types and induce distinct cell behavior.
    Blood. 2022;140:99-111.
    PubMed     Abstract available

  5. WEHLING A, Loeffler D, Zhang Y, Kull T, et al
    Combined single-cell tracking and omics improves blood stem cell fate regulator identification.
    Blood. 2022 Jul 12. pii: 485878. doi: 10.1182/blood.2022016880.
    PubMed     Abstract available

    June 2022
  6. ALJOUFI A, Zhang C, Ropa J, Chang W, et al
    Physioxia induced Downregulation of Tet2 in Hematopoietic Stem Cells contributes to Enhanced Self-renewal.
    Blood. 2022 Jun 30. pii: 485747. doi: 10.1182/blood.2022015499.
    PubMed     Abstract available

  7. LI J, Williams MJ, Park HJ, Bastos HP, et al
    STAT1 is essential for HSC function and maintains MHCIIhi stem cells that resists myeloablation and neoplastic expansion.
    Blood. 2022 Jun 29. pii: 485724. doi: 10.1182/blood.2021014009.
    PubMed     Abstract available

  8. Liu Y, Chen Q, Jeong H-W, et al. Dopamine signaling regulates hematopoietic stem and progenitor cell function. Blood. 2021;138(21):2051-2065.
    Blood. 2022;139:3668.

  9. LI B, An W, Wang H, Baslan T, et al
    BMP2/SMAD pathway activation in JAK2/p53-mutant megakaryocyte/erythroid progenitors promotes leukemic transformation.
    Blood. 2022;139:3630-3646.
    PubMed     Abstract available

    Extramedullary hematopoietic stem cells.
    Blood. 2022;139:3353-3354.

  11. MENDE N, Bastos HP, Santoro A, Mahbubani KT, et al
    Unique molecular and functional features of extramedullary hematopoietic stem and progenitor cell reservoirs in humans.
    Blood. 2022;139:3387-3401.
    PubMed     Abstract available

  12. KAPENI C, Nitsche L, Kilpatrick AM, Wilson NK, et al
    p57Kip2 regulates embryonic blood stem cells by controlling sympathoadrenal progenitor expansion.
    Blood. 2022 Jun 2. pii: 485456. doi: 10.1182/blood.2021014853.
    PubMed     Abstract available

  13. Henden AS, Koyama M, Robb RJ, et al. IFN-lambda therapy prevents severe gastrointestinal graft-versus-host disease. Blood. 2021;138(8):722-737.
    Blood. 2022;139:3346-3351.

  14. Yu Z, Yang W, He X, et al. Endothelial cell-derived angiopoietin-like protein 2 supports hematopoietic stem cell activities in bone marrow niches. Blood. 2022;139(10):1529-1540.
    Blood. 2022;139:3352.

  15. DAVENPORT P, Liu ZJ, Sola-Visner M
    Fetal vs adult megakaryopoiesis.
    Blood. 2022;139:3233-3244.
    PubMed     Abstract available

  16. TILBURG J, Becker IC, Italiano JE
    Don't you forget about me(gakaryocytes).
    Blood. 2022;139:3245-3254.
    PubMed     Abstract available

    May 2022
  17. KEYVANI CHAHI A, Belew MS, Xu J, Chen HTT, et al
    PLAG1 dampens protein synthesis to promote human hematopoietic stem cell self-renewal.
    Blood. 2022 May 31. pii: 485426. doi: 10.1182/blood.2021014698.
    PubMed     Abstract available

    RIG-Ing out BMSCs for hematopoietic recovery after transplantation.
    Blood. 2022;139:3107-3109.

  19. YANG Y, Mumau M, Tober J, Zhu Q, et al
    Endothelial MEKK3-KLF2/4 signaling integrates inflammatory and hemodynamic signals during definitive hematopoiesis.
    Blood. 2022;139:2942-2957.
    PubMed     Abstract available

    April 2022
  20. ZHU J, Wang Y, Li JX, Das PK, et al
    Donor Plasmacytoid Dendritic Cells Limit Graft-versus-Host Disease Through Vasoactive Intestinal Polypeptide Expression.
    Blood. 2022 Apr 20. pii: 485002. doi: 10.1182/blood.2021012561.
    PubMed     Abstract available

  21. OVERBEEKE C, Tak T, Koenderman L
    The journey of neutropoiesis: how complex landscapes in bone marrow guide continuous neutrophil lineage determination.
    Blood. 2022;139:2285-2293.
    PubMed     Abstract available

  22. WANG M, Dingler FA, Patel KJ
    Genotoxic aldehydes in the hematopoietic system.
    Blood. 2022;139:2119-2129.
    PubMed     Abstract available

    March 2022

  23. Psatha N, Georgakopoulou A, Li C, et al. Enhanced HbF reactivation by multiplex mutagenesis of thalassemic CD34+ cells in vitro and in vivo. Blood. 2021;138(17):1540-1553.
    Blood. 2022;139:2087.

    RNA missplicing and ring sideroblasts in MDS.
    Blood. 2022;139:1933-1935.

  25. ALBERT MH, Sirait T, Eikema DJ, Bakunina K, et al
    Hematopoietic stem cell transplantation for adolescents and adults with inborn errors of immunity, an EBMT IEWP study.
    Blood. 2022 Mar 28. pii: 484506. doi: 10.1182/blood.2022015506.
    PubMed     Abstract available

  26. Cutler C, Lee SJ, Arai S, et al. Belumosudil for chronic graft-versus-host disease after 2 or more prior lines of therapy: the ROCKstar study. Blood. 2021;138(22):2278-2289.
    Blood. 2022;139:1772.

  27. LOU Q, Jiang K, Xu Q, Yuan L, et al
    The RIG-I-NRF2 axis regulates the mesenchymal stromal niche for bone marrow transplantation.
    Blood. 2022 Mar 8. pii: 484313. doi: 10.1182/blood.2021013048.
    PubMed     Abstract available

    PP2A activation targets AML stem cells.
    Blood. 2022;139:1267-1269.

  29. SUO M, Rommelfanger MK, Chen Y, Amro EM, et al
    Age-dependent effects of Igf2bp2 on gene regulation, function, and aging of hematopoietic stem cells in mice.
    Blood. 2022 Mar 1. pii: 484215. doi: 10.1182/blood.2021012197.
    PubMed     Abstract available

    February 2022
  30. LV K, Tong W
    Waking up CML leukemia stem cells for the kill.
    Blood. 2022;139:647-648.

  31. LANDSPERSKY T, Sacma M, Riviere J, Hecker JS, et al
    Autophagy in mesenchymal progenitors protects mice against bone marrow failure after severe intermittent stress.
    Blood. 2022;139:690-703.
    PubMed     Abstract available

    January 2022
  32. ALBERT MH, Slatter MA, Gennery AR, Gungor T, et al
    Hematopoietic stem cell transplantation for Wiskott-Aldrich syndrome: an EBMT inborn errors working party analysis.
    Blood. 2022 Jan 31. pii: 483752. doi: 10.1182/blood.2021014687.
    PubMed     Abstract available

  33. CHIN DWL, Yoshizato T, Virding Culleton S, Grasso F, et al
    Aged healthy mice acquire clonal hematopoiesis mutations.
    Blood. 2022;139:629-634.

  34. STONE AP, Nascimento TF, Barrachina MN
    The bone marrow niche from the inside out: how megakaryocytes are shaped by and shape hematopoiesis.
    Blood. 2022;139:483-491.
    PubMed     Abstract available

  35. LAN Y
    Deciphering the continuum of hemogenic endothelium differentiation.
    Blood. 2022;139:308-310.

  36. FADLULLAH MZH, Neo WH, Lie-A-Ling M, Thambyrajah R, et al
    Murine AGM single-cell profiling identifies a continuum of hemogenic endothelium differentiation marked by ACE.
    Blood. 2022;139:343-356.
    PubMed     Abstract available

  37. LOPEZ DE LAPUENTE PORTILLA A, Ekdahl L, Cafaro C, Ali Z, et al
    Genome-wide association study on 13,167 individuals identifies regulators of blood CD34+ cell levels.
    Blood. 2022 Jan 10. pii: 483405. doi: 10.1182/blood.2021013220.
    PubMed     Abstract available

  38. SAHA A, Hyzy S, Lamothe TL, Hammond KJ, et al
    CD45-targeted antibody-drug-conjugate successfully conditions for allogeneic hematopoietic stem cell transplantation.
    Blood. 2022 Jan 5. pii: 483334. doi: 10.1182/blood.2021012366.
    PubMed     Abstract available

    December 2021
  39. CAI H, Kondo M, Sandhow L, Xiao P, et al
    Critical Role of Lama4 for Hematopoiesis Regeneration and Acute Myeloid Leukemia Progression.
    Blood. 2021 Dec 27. pii: 483253. doi: 10.1182/blood.2021011510.
    PubMed     Abstract available

  40. YU Z, Yang W, He X, Chen C, et al
    Endothelial cell-derived angiopoietin-like protein 2 supports hematopoietic stem cell activities in bone marrow niches.
    Blood. 2021 Dec 20. pii: 483187. doi: 10.1182/blood.2021011644.
    PubMed     Abstract available

  41. GANUZA M, Clements WK, McKinney Freeman SL
    Specification of hematopoietic stem cells in mammalian embryos: A rare or frequent event?
    Blood. 2021 Dec 17. pii: 483085. doi: 10.1182/blood.2020009839.
    PubMed     Abstract available

    HSC engraftment in SCD: a MiSCing piece of the puzzle?
    Blood. 2021;138:2451-2452.

  43. MIYAUCHI M, Ito Y, Nakahara F, Hino T, et al
    Efficient production of human neutrophils from iPSCs that prevent murine lethal infection with immune cell recruitment.
    Blood. 2021;138:2555-2569.
    PubMed     Abstract available

  44. TANG A, Strat AN, Rahman M, Zhang H, et al
    Murine bone marrow mesenchymal stromal cells have reduced hematopoietic maintenance ability in sickle cell disease.
    Blood. 2021;138:2570-2582.
    PubMed     Abstract available

  45. CHEN Y, Wang D
    STAT5B, the dominant twin, in hematopoietic stem cells.
    Blood. 2021;138:2303-2305.

  46. QIU Y, Xu M, Huang S
    Long noncoding RNAs: emerging regulators of normal and malignant hematopoiesis.
    Blood. 2021;138:2327-2336.
    PubMed     Abstract available

  47. WEEKS LD, Marinac CR, Redd RA, Abel GA, et al
    Age-related Diseases of Inflammation in Myelodysplastic Syndrome and Chronic Myelomonocytic Leukemia.
    Blood. 2021 Dec 7. pii: 482919. doi: 10.1182/blood.2021014418.

  48. CHEN C, Yu W, Alikarami F, Qiu Q, et al
    Single-cell multiomics reveals increased plasticity, resistant populations and stem-cell-like blasts in KMT2A-rearranged leukemia.
    Blood. 2021 Dec 5. pii: 482898. doi: 10.1182/blood.2021013442.
    PubMed     Abstract available

  49. MOSCA M, Hermange G, Tisserand A, Noble R, et al
    Inferring the dynamics of mutated hematopoietic stem and progenitor cells induced by IFNalpha in myeloproliferative neoplasms.
    Blood. 2021;138:2231-2243.
    PubMed     Abstract available

    November 2021
    Dopamine motivates stem cells for reward.
    Blood. 2021;138:2012-2014.

  51. LIU Y, Chen Q, Jeong HW, Han D, et al
    Dopamine signaling regulates hematopoietic stem and progenitor cell function.
    Blood. 2021;138:2051-2065.
    PubMed     Abstract available

  52. LADEL L, Jamieson CHM
    Upping the antizyme: AZIN1 directs stem cell fate.
    Blood. 2021;138:1910-1911.

  53. ZHANG H, Wang S, Liu D, Gao C, et al
    EpoR-tdTomato-Cre mice enable identification of EpoR expression in subsets of tissue macrophages and hematopoietic cells.
    Blood. 2021;138:1986-1997.
    PubMed     Abstract available

  54. BRAND M
    Epigenetic plasticity of erythroid progenitors.
    Blood. 2021;138:1646-1648.

  55. FENG Y, Feng W
    Numerous ring sideroblasts in chronic neutrophilic leukemia.
    Blood. 2021;138:1783.

  56. FUCHS EJ, McCurdy SR, Solomon SR, Wang T, et al
    HLA Informs Risk Predictions after Haploidentical Stem Cell Transplantation with Post-transplantation Cyclophosphamide.
    Blood. 2021 Nov 1. pii: 477735. doi: 10.1182/blood.2021013443.
    PubMed     Abstract available

  57. YANG Y, Kueh AJ, Grant Z, Abeysekera W, et al
    The histone lysine acetyltransferase HBO1 (KAT7) regulates hematopoietic stem cell quiescence and self-renewal.
    Blood. 2021 Nov 1. pii: 477737. doi: 10.1182/blood.2021013954.
    PubMed     Abstract available

    October 2021
  58. SCHNOEDER TM, Schwarzer A, Jayavelu AK, Hsu CJ, et al
    PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.
    Blood. 2021 Oct 25. pii: S0006-4971(21)01783-3. doi: 10.1182/blood.2021012778.
    PubMed     Abstract available

  59. DOCAMPO MD, Burgos da Silva M, Lazrak A, Nichols KB, et al
    Alloreactive T cells deficient of the short-chain fatty acid receptor GPR109A induce less graft-versus-host disease.
    Blood. 2021 Oct 15. pii: 477329. doi: 10.1182/blood.2021010719.
    PubMed     Abstract available

  60. FISHMAN H, Madiwale S, Geron I, Bari V, et al
    ETV6-NCOA2 fusion induces T/Myeloid mixed-phenotype leukemia by transformation of non-thymic hematopoietic progenitors.
    Blood. 2021 Oct 8. pii: 477216. doi: 10.1182/blood.2020010405.
    PubMed     Abstract available

    September 2021
    Evading eviction: leukemic stem cell squatters.
    Blood. 2021;138:1007-1008.

  62. SUBBURAJ D, Ng B, Kariminia A, Abdossamadi S, et al
    Metabolomic Identification of Alpha-Ketoglutaric Acid Elevation in Pediatric Chronic Graft-versus-Host Disease.
    Blood. 2021 Sep 17. pii: 476943. doi: 10.1182/blood.2021013244.
    PubMed     Abstract available

  63. KOVTONYUK LV, Caiado F, Garcia-Martin S, Manz EM, et al
    IL-1 Mediates Microbiome-Induced Inflamm-Ageing of Hematopoietic Stem Cells in Mice.
    Blood. 2021 Sep 15. pii: 476914. doi: 10.1182/blood.2021011570.
    PubMed     Abstract available

  64. AMAYA M, Inguva A, Pei S, Jones CL, et al
    The STAT3-MYC Axis Promotes Survival of Leukemia Stem Cells by Regulating SLC1A5 and Oxidative Phosphorylation.
    Blood. 2021 Sep 15. pii: 476917. doi: 10.1182/blood.2021013201.
    PubMed     Abstract available

  65. TERMINI CM, Pang A, Li M, Fang T, et al
    Syndecan-2 expression enriches for hematopoietic stem cells and regulates stem cell repopulating capacity.
    Blood. 2021 Sep 10. pii: 476854. doi: 10.1182/blood.2020010447.
    PubMed     Abstract available

  66. LEHNERTZ B, Chagraoui J, MacRae T, Tomellini E, et al
    HLF Expression Defines the Human Hematopoietic Stem Cell State.
    Blood. 2021 Sep 9. pii: 476838. doi: 10.1182/blood.2021010745.
    PubMed     Abstract available

  67. DAVIS AG, Johnson DT, Zheng D, Wang R, et al
    Alternative polyadenylation dysregulation contributes to the differentiation block of acute myeloid leukemia.
    Blood. 2021 Sep 5. pii: 476791. doi: 10.1182/blood.2020005693.
    PubMed     Abstract available

    August 2021
  68. HENDEN AS, Koyama M, Robb RJ, Forero A, et al
    IFN-lambda therapy prevents severe gastrointestinal graft-versus-host disease.
    Blood. 2021;138:722-737.
    PubMed     Abstract available

  69. COCHRAN T, Li W
    Frequent internuclear bridging in a Fanconi anemia patient with FANCG mutation.
    Blood. 2021;138:738.

  70. JANN JC, Tothova Z
    Cohesin mutations in myeloid malignancies.
    Blood. 2021;138:649-661.
    PubMed     Abstract available

  71. WANG F, He J, Liu S, Gao A, et al
    Comprehensive RNA editome reveals that edited Azin1 partners with DDX1 to enable hematopoietic stem cell differentiation.
    Blood. 2021 Aug 13. pii: 476580. doi: 10.1182/blood.2021011314.
    PubMed     Abstract available

  72. CHAKRAVERTY R, Teshima T
    Graft-versus-host disease: a disorder of tissue regeneration and repair.
    Blood. 2021 Aug 9. pii: 476531. doi: 10.1182/blood.2021011867.
    PubMed     Abstract available

  73. YANG S, Zhu XN, Zhang HL, Yang Q, et al
    ANP32B-mediated repression of p53 contributes to maintenance of normal and CML stem cells.
    Blood. 2021 Aug 6. pii: 476526. doi: 10.1182/blood.2020010400.
    PubMed     Abstract available

    July 2021
  74. KOLLMANN S, Grausenburger R, Klampfl T, Prchal-Murphy M, et al
    A STAT5B-CD9 axis determines self-renewal in hematopoietic and leukemic stem cells.
    Blood. 2021 Jul 28. pii: 476469. doi: 10.1182/blood.2021010980.
    PubMed     Abstract available

  75. LOEFFLER D, Schneiter F, Wang W, Wehling A, et al
    Asymmetric organelle inheritance predicts human blood stem cell fate.
    Blood. 2021 Jul 27. pii: 476461. doi: 10.1182/blood.2020009778.
    PubMed     Abstract available

  76. TU Z, Wang C, Davis AK, Hu M, et al
    The chromatin remodeler CHD8 governs hematopoietic stem/progenitor survival by regulating ATM-mediated P53 protein stability.
    Blood. 2021;138:221-233.
    PubMed     Abstract available

  77. CUTLER CS, Lee SJ, Arai S, Rotta M, et al
    Belumosudil for Chronic Graft-versus-Host Disease (cGVHD) After 2 or More Prior Lines of Therapy: The ROCKstar Study.
    Blood. 2021 Jul 15. pii: 476399. doi: 10.1182/blood.2021012021.
    PubMed     Abstract available

  78. GURNARI C, Pagliuca S, Durkin L, Terkawi L, et al
    Vacuolization of hematopoietic precursors: an enigma with multiple etiologies.
    Blood. 2021;137:3685-3689.

    June 2021
    Immune control of cytomegalovirus reactivation in stem cell transplantation.
    Blood. 2021 Jun 24. pii: 476240. doi: 10.1182/blood.2020010028.
    PubMed     Abstract available

  80. MIKDAR M, Gonzalez-Menendez P, Cai X, Zhang Y, et al
    The equilibrative nucleoside transporter ENT1 is critical for nucleotide homeostasis and optimal erythropoiesis.
    Blood. 2021;137:3548-3562.
    PubMed     Abstract available

  81. SOMMERKAMP P, Romero-Mulero MC, Narr A, Ladel L, et al
    Mouse multipotent progenitor 5 cells are located at the interphase between hematopoietic stem and progenitor cells.
    Blood. 2021;137:3218-3224.
    PubMed     Abstract available

  82. PASTORET C, Desmots F, Drillet G, Le Gallou S, et al
    Linking the KIR phenotype with STAT3 and TET2 mutations to identify chronic lymphoproliferative disorders of NK cells.
    Blood. 2021;137:3237-3250.
    PubMed     Abstract available

  83. BRAULT J, Liu TQ, Bello EA, Liu S, et al
    CRISPR-targeted MAGT1 insertion restores XMEN patient hematopoietic stem cells and lymphocytes.
    Blood. 2021 Jun 4. pii: 476069. doi: 10.1182/blood.2021011192.
    PubMed     Abstract available

  84. PSATHA N, Georgakopoulou A, Li C, Nandakumar V, et al
    Enhanced HbF reactivation by multiplex mutagenesis of thalassemic CD34+ cells in vitro and in vivo.
    Blood. 2021 Jun 4. pii: 476068. doi: 10.1182/blood.2020010020.
    PubMed     Abstract available

  85. YEH AC, Varelias A, Reddy A, Barone SM, et al
    CMV exposure drives long-term CD57+ CD4 memory T cell inflation following allogeneic stem cell transplant.
    Blood. 2021 Jun 3. pii: 476063. doi: 10.1182/blood.2020009492.
    PubMed     Abstract available

  86. SCHURCH CM, Caraccio C, Nolte MA
    Diversity, localization, and (patho)physiology of mature lymphocyte populations in the bone marrow.
    Blood. 2021;137:3015-3026.
    PubMed     Abstract available

  87. SOMASUNDARAM R, Jensen CT, Tingvall-Gustafsson J, Ahsberg J, et al
    EBF1 and PAX5 control pro-B cell expansion via opposing regulation of the Myc gene.
    Blood. 2021;137:3037-3049.
    PubMed     Abstract available

  88. THOMS JAI, Truong P, Subramanian S, Knezevic K, et al
    Disruption of a GATA2, TAL1, ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells.
    Blood. 2021 Jun 1. pii: 476046. doi: 10.1182/blood.2020009707.
    PubMed     Abstract available

    May 2021
  89. MAAS-BAUER K, Lohmeyer JK, Hirai T, Lopes Ramos T, et al
    Invariant Natural Killer T Cell Subsets Have Diverse Graft-Versus-Host-Disease-Preventing and Anti-Tumor Effects.
    Blood. 2021 May 25. pii: 476015. doi: 10.1182/blood.2021010887.
    PubMed     Abstract available

  90. LIU H
    Basophilic myeloblasts: a clue for CML blast phase.
    Blood. 2021;137:2852.

  91. BORELLA G, Da Ros A, Borile G, Porcu E, et al
    Targeting mesenchymal stromal cells plasticity to reroute acute myeloid leukemia course.
    Blood. 2021 May 19. pii: 475978. doi: 10.1182/blood.2020009845.
    PubMed     Abstract available

  92. WANG W, Zhang Y, Dettinger P, Reimann A, et al
    Cytokine combinations for human blood stem cell expansion induce cell type- and cytokine-specific signaling dynamics.
    Blood. 2021 May 14. pii: 475970. doi: 10.1182/blood.2020008386.
    PubMed     Abstract available

  93. TAKEDA MR, Gurbuxani S
    bcr3 PML-RARA: short fusion, small blasts!
    Blood. 2021;137:2708.

  94. SURAPALLY S, Tenen DG, Pulikkan JA
    Emerging therapies for inv(16) AML.
    Blood. 2021;137:2579-2584.
    PubMed     Abstract available

  95. DE RAVIN SS, Brault J, Meis RJ, Liu S, et al
    Enhanced homology-directed repair for highly efficient gene editing in hematopoietic stem/progenitor cells.
    Blood. 2021;137:2598-2608.
    PubMed     Abstract available

  96. ESTEVEZ B, Borst S, Jarocha D, Sudunagunta V, et al
    RUNX-1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells.
    Blood. 2021;137:2662-2675.
    PubMed     Abstract available

  97. SILVA AP, Almeida ARM, Cachucho A, Neto JL, et al
    Overexpression of wild type IL-7Ralpha promotes T-cell acute lymphoblastic leukemia/lymphoma.
    Blood. 2021 May 10. pii: 475938. doi: 10.1182/blood.2019000553.
    PubMed     Abstract available

  98. ANAND P, Guillaumet-Adkins A, Dimitrova V, Yun H, et al
    Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL.
    Blood. 2021;137:2463-2480.
    PubMed     Abstract available

  99. HENDEN AS, Koyama M, Robb RJ, Forero A, et al
    IFNlambda Therapy Prevents Severe Gastrointestinal Graft-versus-Host Disease.
    Blood. 2021 May 5. pii: 475908. doi: 10.1182/blood.2020006375.
    PubMed     Abstract available

    April 2021
  100. DUNBAR A, Levine RL
    "Interferon" with MPN hematopoietic stem cells.
    Blood. 2021;137:2129-2130.

  101. SVENDSEN AF, Yang D, Kim KM, Lazare SS, et al
    A comprehensive transcriptome signature of murine hematopoietic stem cell aging.
    Blood. 2021 Apr 19. pii: 475784. doi: 10.1182/blood.2020009729.
    PubMed     Abstract available

  102. JUNG M, Smogorzewska A
    Endogenous formaldehyde destroys blood stem cells.
    Blood. 2021;137:1988-1990.

    "Mast"ering drug discovery with iPSCs.
    Blood. 2021;137:1993-1994.

    March 2021
  104. NIU X, Rothe K, Chen M, Grasedieck S, et al
    Targeting AXL Kinase Sensitizes Leukemic Stem and Progenitor Cells to Venetoclax Treatment in Acute Myeloid Leukemia.
    Blood. 2021 Mar 30. pii: 475648. doi: 10.1182/blood.2020007651.
    PubMed     Abstract available

  105. ZHU C, Lian Y, Wang C, Wu P, et al
    Single-cell transcriptomics dissects hematopoietic cell destruction and T cell engagement in aplastic anemia.
    Blood. 2021 Mar 24. pii: 475591. doi: 10.1182/blood.2020008966.
    PubMed     Abstract available

  106. CALVI LM
    FGF-23: a novel actor in stem cell mobilization.
    Blood. 2021;137:1434-1436.

  107. RASLAN O, Hsia CC
    Cabot rings in acute myeloid leukemia.
    Blood. 2021;137:1560.

  108. ISHII S, Suzuki T, Wakahashi K, Asada N, et al
    FGF-23 from erythroblasts promotes hematopoietic progenitor mobilization.
    Blood. 2021;137:1457-1467.
    PubMed     Abstract available

  109. NAKAMURA-ISHIZU A, Chin D, Matsumura T, Tan DQ, et al
    Prolonged maintenance of hematopoietic stem cells that escape from Thrombopoietin deprivation.
    Blood. 2021 Mar 3. pii: 475410. doi: 10.1182/blood.2020005517.
    PubMed     Abstract available

    February 2021
  110. ELSAID R, Meunier S, Burlen-Defranoux O, Soares-da-Silva F, et al
    A wave of bipotent T/ILC-restricted progenitors shapes the embryonic thymus microenvironment in a time-dependent manner.
    Blood. 2021;137:1024-1036.
    PubMed     Abstract available

  111. RAO TN, Hansen N, Stetka J, Luque Paz D, et al
    JAK2-V617F and interferon-alpha induce megakaryocyte-biased stem cells characterized by decreased long-term functionality.
    Blood. 2021 Feb 24. pii: 475343. doi: 10.1182/blood.2020005563.
    PubMed     Abstract available

  112. CHENG T, Hu L, Yin X, Zhang Y, et al
    Radiation-induced bystander effects impair transplanted human hematopoietic stem cells via oxidative DNA damage.
    Blood. 2021 Feb 24. pii: 475344. doi: 10.1182/blood.2020007362.
    PubMed     Abstract available

  113. DUMONTET E, Pangault C, Roulois D, Desoteux M, et al
    Extracellular vesicles shed by follicular lymphoma B cells promote the polarization of bone marrow stromal cell niche.
    Blood. 2021 Feb 24. pii: 475345. doi: 10.1182/blood.2020008791.
    PubMed     Abstract available

  114. WANG N, Yin J, You N, Yang S, et al
    TWIST1 preserves hematopoietic stem cell function via CACNA1B/Ca2+/mitochondria axis.
    Blood. 2021 Feb 22. pii: 475282. doi: 10.1182/blood.2020007489.
    PubMed     Abstract available

  115. MIDDLETON EA, Rowley JW
    eQTLs in platelets and iPSC-megakaryocytes.
    Blood. 2021;137:869-870.

  116. GU Y, Yang R, Yang Y, Zhao Y, et al
    IDH1 mutation contributes to myeloid dysplasia in mice by disturbing heme biosynthesis and erythropoiesis.
    Blood. 2021;137:945-958.
    PubMed     Abstract available

  117. KAMMERS K, Taub MA, Rodriguez B, Yanek LR, et al
    Transcriptional profile of platelets and iPSC-derived megakaryocytes from whole-genome and RNA sequencing.
    Blood. 2021;137:959-968.
    PubMed     Abstract available

  118. SHAO L, Elujoba-Bridenstine A, Zink KE, Sanchez LM, et al
    The neurotransmitter receptor Gabbr1 regulates proliferation and function of hematopoietic stem and progenitor cells.
    Blood. 2021;137:775-787.
    PubMed     Abstract available

  119. GRANT S
    Targeting cereblon in AML.
    Blood. 2021;137:584-586.

  120. RAASTAD K, Huang Q
    Burkitt leukemia with immature B-cell phenotype mimicking acute lymphoblastic leukemia.
    Blood. 2021;137:718.

  121. SHENG Y, Ma R, Yu C, Wu Q, et al
    Role of c-Myc haploinsufficiency in the maintenance of HSCs in mice.
    Blood. 2021;137:610-623.
    PubMed     Abstract available

  122. FALINI B, Brunetti L, Martelli MP
    How I diagnose and treat NPM1-mutated AML.
    Blood. 2021;137:589-599.
    PubMed     Abstract available

  123. JIA W, Poe JC, Su H, Anand S, et al
    BAFF Promotes Heightened BCR Responsiveness and Manifestations of Chronic GVHD after Allogeneic Stem Cell Transplantation.
    Blood. 2021 Feb 3. pii: 475149. doi: 10.1182/blood.2020008040.
    PubMed     Abstract available

  124. ZHANG Y, Shen L, Dreissigacker K, Zhu H, et al
    Targeting of canonical WNT signaling ameliorates experimental sclerodermatous chronic graft-versus-host disease.
    Blood. 2021 Feb 2. pii: 475143. doi: 10.1182/blood.2020008720.
    PubMed     Abstract available

    January 2021
  125. COHEN AUBART F, Roos-Weil D, Armand M, Marceau-Renaut A, et al
    High frequency of clonal hematopoiesis in Erdheim-Chester disease.
    Blood. 2021;137:485-492.
    PubMed     Abstract available

  126. SONG Q, Wang X, Wu X, Qin H, et al
    Tolerogenic anti-IL-2 mAb prevents graft-versus-host disease while preserving strong graft-versus-leukemia activity.
    Blood. 2021 Jan 27. pii: 475053. doi: 10.1182/blood.2020006345.
    PubMed     Abstract available

  127. FUCHS EJ, O'Donnell PV, Eapen M, Logan B, et al
    Double unrelated umbilical cord blood vs HLA-haploidentical bone marrow transplantation: the BMT CTN 1101 trial.
    Blood. 2021;137:420-428.
    PubMed     Abstract available

  128. DING Y, Wang W, Ma D, Liang G, et al
    Smarca5-mediated epigenetic programming facilitates fetal HSPC development in vertebrates.
    Blood. 2021;137:190-202.
    PubMed     Abstract available

  129. MU A, Hira A, Niwa A, Osawa M, et al
    Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency.
    Blood. 2021 Jan 12. pii: 474923. doi: 10.1182/blood.2020009111.
    PubMed     Abstract available

  130. LE GOFF S, Boussaid I, Floquet C, Raimbault A, et al
    p53 activation during ribosome biogenesis regulates normal erythroid differentiation.
    Blood. 2021;137:89-102.
    PubMed     Abstract available

    December 2020
    Blood stem cells SELect quiescence.
    Blood. 2020;136:2967-2968.

  132. MYLLYMAKI M, Redd R, Reilly CR, Saber W, et al
    Short telomere length predicts nonrelapse mortality after stem cell transplantation for myelodysplastic syndrome.
    Blood. 2020;136:3070-3081.
    PubMed     Abstract available

  133. TOLEDO MAS, Gatz M, Sontag S, Gleixner KV, et al
    Nintedanib Targets KIT D816V Neoplastic Cells Derived from Induced Pluripotent Stem cells of Systemic Mastocytosis.
    Blood. 2020 Dec 23. pii: 474778. doi: 10.1182/blood.2019004509.
    PubMed     Abstract available

  134. Garcia-Garcia A, Korn C, Garcia-Fernandez M, et al. Dual cholinergic signals regulate daily migration of hematopoietic stem cells and leukocytes. Blood. 2019;133(3):224-236.
    Blood. 2020;136:2965.

  135. FIDANZA A, Stumpf PS, Ramachandran P, Tamagno S, et al
    Single-cell analyses and machine learning define hematopoietic progenitor and HSC-like cells derived from human PSCs.
    Blood. 2020;136:2893-2904.
    PubMed     Abstract available

  136. LYNE AM, Laplane L, Perie L
    To portray clonal evolution in blood cancer, count your stem cells.
    Blood. 2020 Dec 11. pii: 474602. doi: 10.1182/blood.2020008407.
    PubMed     Abstract available

  137. PUERTA-ALCALDE P, Champlin RE, Kontoyiannis DP
    How I perform hematopoietic stem cell transplantation on patients with a history of invasive fungal disease.
    Blood. 2020;136:2741-2753.
    PubMed     Abstract available

  138. STAUBER J, Greally J, Steidl U
    Preleukemic and Leukemic Evolution at the Stem Cell Level.
    Blood. 2020 Dec 4. pii: 474417. doi: 10.1182/blood.2019004397.
    PubMed     Abstract available

    HSCs revive their niche after transplantation.
    Blood. 2020;136:2597-2598.

  140. GOLAN K, Singh AK, Kollet O, Bertagna M, et al
    Bone marrow regeneration requires mitochondrial transfer from donor Cx43-expressing hematopoietic progenitors to stroma.
    Blood. 2020;136:2607-2619.
    PubMed     Abstract available

    November 2020
  141. HOPE KJ
    Making a bet on RET for hematopoietic stem cell expansion.
    Blood. 2020;136:2484-2486.

  142. STAAL FJT, Fibbe WE
    BETting on stem cell expansion.
    Blood. 2020;136:2364-2365.

  143. RAO S
    RUNX1 and inv(16) are frenemies in AML.
    Blood. 2020;136:2361-2362.

  144. HUA P, Hester J, Adigbli G, Li R, et al
    The BET inhibitor CPI203 promotes ex vivo expansion of cord blood long-term repopulating HSCs and megakaryocytes.
    Blood. 2020;136:2410-2415.
    PubMed     Abstract available

  145. SURKA C, Jin L, Mbong N, Lu CC, et al
    CC-90009, a novel cereblon E3 ligase modulator targets acute myeloid leukemia blasts and leukemia stem cells.
    Blood. 2020 Nov 16. pii: 474181. doi: 10.1182/blood.2020008676.
    PubMed     Abstract available

  146. GRECO R, Nitti R, Mancini N, Pasciuta R, et al
    Microbiome Markers are Early Predictors of Acute GvHD in Allogeneic Hematopoietic Stem Cell Transplant recipients.
    Blood. 2020 Nov 10. pii: 474128. doi: 10.1182/blood.2020007158.

  147. HANEKAMP D, Ngai LL, Janssen JJ, van de Loosdrecht AA, et al
    Early assessment of clofarabine effectiveness applying measurable residual disease, including AML stem cells.
    Blood. 2020 Nov 10. pii: 474126. doi: 10.1182/blood.2020007150.

  148. XIAO Y, van Halteren AGS, Lei X, Borst J, et al
    Bone marrow-derived myeloid progenitors as driver mutation carriers in high- and low-risk Langerhans cell histiocytosis.
    Blood. 2020;136:2188-2199.
    PubMed     Abstract available

  149. SUBRAMANIAM A, Zemaitis K, Talkhoncheh MS, Yudovich D, et al
    Lysine-specific demethylase 1A restricts ex vivo propagation of human HSCs and is a target of UM171.
    Blood. 2020;136:2151-2161.
    PubMed     Abstract available

  150. YOON IC, Bascou NA, Poe MD, Szabolcs P, et al
    Long-Term Neurodevelopmental Outcomes of Hematopoietic Stem Cell Transplantation for Late-Infantile Krabbe Disease.
    Blood. 2020 Nov 4. pii: 474073. doi: 10.1182/blood.2020005477.
    PubMed     Abstract available

  151. LIU L, Inoki A, Fan K, Mao F, et al
    ER associated degradation preserves hematopoietic stem cell quiescence and self-renewal by restricting mTOR activity.
    Blood. 2020 Nov 4. pii: 474082. doi: 10.1182/blood.2020007975.
    PubMed     Abstract available

  152. DE KONING C, Prockop S, Roessel IV, Kernan NA, et al
    CD4+ T-cell reconstitution predicts Survival Outcomes after acute Graft-versus-Host-Disease; a dual center validation.
    Blood. 2020 Nov 4. pii: 474078. doi: 10.1182/blood.2020007905.
    PubMed     Abstract available

    October 2020
  153. YUAN CY, Zhou V, Sauber G, Stollenwerk TM, et al
    Signaling Through the Type 2 Cannabinoid Receptor Regulates the Severity of Acute and Chronic Graft versus Host Disease.
    Blood. 2020 Oct 7. pii: 464166. doi: 10.1182/blood.2020004871.
    PubMed     Abstract available

  154. TSAI FD, Lindsley RC
    Clonal hematopoiesis in the inherited bone marrow failure syndromes.
    Blood. 2020;136:1615-1622.
    PubMed     Abstract available

  155. TAKEDA R, Asada S, Park SJ, Yokoyama A, et al
    HHEX promotes myeloid transformation in cooperation with mutant ASXL1.
    Blood. 2020;136:1670-1684.
    PubMed     Abstract available

    September 2020
  156. CURTIS LM, Ostojic A, Venzon D, Holtzman NG, et al
    A randomized phase-2 trial of pomalidomide in subjects failing prior therapy of chronic graft-versus-host disease.
    Blood. 2020 Sep 24. pii: 463981. doi: 10.1182/blood.2020006892.
    PubMed     Abstract available

  157. CHAO NJ
    I have a gut feeling....
    Blood. 2020;136:1380.

  158. ZHEN T, Cao Y, Ren G, Zhao L, et al
    RUNX1 and CBFbeta-SMMHC transactivate target genes together in abnormal myeloid progenitors for leukemia development.
    Blood. 2020 Sep 14. pii: 463758. doi: 10.1182/blood.2020007747.
    PubMed     Abstract available

  159. WILL B
    No keto for AML stem cells!
    Blood. 2020;136:1219-1221.

  160. KAWABATA KC, Zong H, Meydan C, Wyman S, et al
    BCL6 maintains survival and self-renewal of primary human acute myeloid leukemia cells.
    Blood. 2020 Sep 10. pii: 463728. doi: 10.1182/blood.2019001745.
    PubMed     Abstract available

  161. RABOSO-GALLEGO J, Casado-Garcia A, Jiang X, Isidro-Hernandez M, et al
    Conditional expression of HGAL leads to the development of diffuse large B-cell lymphoma in mice.
    Blood. 2020 Sep 6. pii: 464123. doi: 10.1182/blood.2020004996.
    PubMed     Abstract available

  162. KANAYAMA M, Izumi Y, Yamauchi Y, Kuroda S, et al
    CD86-based analysis enables observation of bona fide hematopoietic responses.
    Blood. 2020;136:1144-1154.
    PubMed     Abstract available

    August 2020
  163. VILLEVAL JL, Vainchenker W
    Megakaryocytes tame erythropoiesis with TGFbeta1.
    Blood. 2020;136:1016-1017.

  164. WANG HY, Tzachanis D
    Extramedullary early T-cell precursor acute lymphoblastic lymphoma presenting as blast crisis of CML.
    Blood. 2020;136:1112.

  165. CATTO LFB, Borges G, Pinto AL, Cle DV, et al
    Somatic genetic rescue in hematopoietic cells in GATA2 deficiency.
    Blood. 2020;136:1002-1005.

  166. LACAUD G
    Decoding hematopoietic stem cells' birth.
    Blood. 2020;136:775-776.

  167. LO RW, Li L, Pluthero FG, Leung R, et al
    The endoplasmic reticulum protein SEC22B interacts with NBEAL2 and is required for megakaryocyte alpha-granule biogenesis.
    Blood. 2020;136:715-725.
    PubMed     Abstract available

  168. FAGNAN A, Bagger FO, Pique-Borras MR, Ignacimouttou C, et al
    Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers.
    Blood. 2020;136:698-714.
    PubMed     Abstract available

    July 2020
    Targeting the bone marrow niche in hemoglobinopathies.
    Blood. 2020;136:529-531.

  170. FANG T, Zhang Y, Chang VY, Roos M, et al
    Epidermal growth factor receptor-dependent DNA repair promotes murine and human hematopoietic regeneration.
    Blood. 2020;136:441-454.
    PubMed     Abstract available

  171. BLOUIN JM, Ged C, Lalanne M, Lamrissi-Garcia I, et al
    Iron chelation rescues hemolytic anemia and skin photosensitivity in congenital erythropoietic porphyria.
    Blood. 2020 Jul 17. pii: 461423. doi: 10.1182/blood.2020006037.
    PubMed     Abstract available

  172. TAVEIRNE S, Wahlen S, Van Loocke W, Kiekens L, et al
    The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation.
    Blood. 2020;136:288-298.
    PubMed     Abstract available

    Aging, inflammation, and HSC.
    Blood. 2020;136:153-154.

  174. PRINS D, Green AR
    Mutant CALR functions: gains and losses.
    Blood. 2020;136:6-7.

  175. FRIEDRICH C, Barreau S
    A splenic lymphoma/leukemia with a spontaneous blast decrease without treatment.
    Blood. 2020;136:148.

    June 2020
  176. GRANTS JM, Wegrzyn J, Hui T, O'Neill K, et al
    Altered microRNA expression links IL6 and TNF-induced inflammaging with myeloid malignancy in humans and mice.
    Blood. 2020;135:2235-2251.
    PubMed     Abstract available

  177. MA WB, Wang XH, Li CY, Tian HH, et al
    GPS2 promotes erythroid differentiation by control of the stability of EKLF protein.
    Blood. 2020;135:2302-2315.
    PubMed     Abstract available

  178. CHEN BY, Song J, Hu CL, Chen SB, et al
    SETD2 deficiency accelerates MDS-associated leukemogenesis via S100a9 in NHD13 mice and predicts poor prognosis in MDS.
    Blood. 2020;135:2271-2285.
    PubMed     Abstract available

  179. STREMENOVA SPEGAROVA J, Lawless D, Mohamad SMB, Engelhardt KR, et al
    Germline TET2 Loss-Of-Function Causes Childhood Immunodeficiency And Lymphoma.
    Blood. 2020 Jun 9. pii: 460739. doi: 10.1182/blood.2020005844.
    PubMed     Abstract available

  180. KEENAN CR, Iannarella N, Naselli G, Bediaga NG, et al
    Extreme disruption of heterochromatin is required for accelerated hematopoietic aging.
    Blood. 2020;135:2049-2058.
    PubMed     Abstract available

    May 2020
  181. MENSSEN AJ, Walter MJ
    Genetics of Progression from MDS to Secondary Leukemia.
    Blood. 2020 May 19. pii: 456027. doi: 10.1182/blood.2019000942.
    PubMed     Abstract available

  182. ZAMBETTI NA, Firestone AJ, Remsberg JR, Huang BJ, et al
    Genetic disruption of N-RasG12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice.
    Blood. 2020;135:1772-1782.
    PubMed     Abstract available

  183. GEBRU MT, Atkinson JM, Young M, Zhang L, et al
    Glucocorticoids enhance the anti-leukemic activity of FLT3 inhibitors in FLT3 mutant acute myeloid leukemia.
    Blood. 2020 May 12. pii: 455305. doi: 10.1182/blood.2019003124.
    PubMed     Abstract available

  184. RAU RE
    SIRPAssing other xenograft murine models?
    Blood. 2020;135:1612-1614.

    April 2020
  185. SIX E, Guilloux A, Denis A, Lecoules A, et al
    Clonal tracking in gene therapy patients reveals a diversity of human hematopoietic differentiation programs.
    Blood. 2020;135:1219-1231.
    PubMed     Abstract available

    March 2020
  186. LI L, Mitra A, Cui K, Zhao B, et al
    Ldb1 is required for Lmo2 oncogene-induced thymocyte self-renewal and T-cell Acute Lymphoblastic Leukemia.
    Blood. 2020 Mar 16. pii: 452704. doi: 10.1182/blood.2019000794.
    PubMed     Abstract available

  187. BRILL A
    Integrin alpha9beta1: a new target to fight thrombosis.
    Blood. 2020;135:787-788.

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