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Articles published in Invest Ophthalmol Vis Sci

Retrieve available abstracts of 49 articles:
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Single Articles


    February 2026
  1. NAVNEET S, Rohrer B
    CR2-fH, A Targeted Inhibitor of Alternative Complement Pathway Reduces Dry AMD-Like Phenotype in AMD Patient iPSC-derived RPE Cells.
    Invest Ophthalmol Vis Sci. 2026;67:9.
    PubMed     Abstract available


    January 2026
  2. FOROOZANDEH P, Kaplan N, Xu D, Qi X, et al
    Losartan Alleviates Chemical Burn-Induced Limbal Stem Cell Deficiency: Repurposing a Venerable Anti-Hypertension Drug.
    Invest Ophthalmol Vis Sci. 2026;67:35.
    PubMed     Abstract available


  3. SUN X, Liang Y, Liang Y, Li W, et al
    PRPF8 Mutation-Induced Defects in Human iPSC-Derived RPE Are Rescued by Adenine Base Editing.
    Invest Ophthalmol Vis Sci. 2026;67:21.
    PubMed     Abstract available


  4. GUO Y, Luo S, Li W, Wang X, et al
    Ferroptosis in Meibomian Gland Progenitor Cells Contributes to Pathogenesis of Meibomian Gland Dysfunction.
    Invest Ophthalmol Vis Sci. 2026;67:9.
    PubMed     Abstract available


  5. FOROOZANDEH P, Kaplan N, Qi X, Yang W, et al
    PAX6 Deficiency Compromises the Ability of Limbal Epithelial Stem Cells to Properly Differentiate Into Mature Corneal Epithelial Cells.
    Invest Ophthalmol Vis Sci. 2026;67:56.
    PubMed     Abstract available


    December 2025
  6. LEE HJ, Yang S, Cheon EJ, Chung SH, et al
    Characterization of LGR5 as a Definitive and Functional Marker for Human Limbal Epithelial Stem Cells.
    Invest Ophthalmol Vis Sci. 2025;66:20.
    PubMed     Abstract available


  7. ZHANG H, Liu ZY, Wu L, Yuan J, et al
    Retinal Pigment Epithelium Extracellular Vesicles Induce Microglia Polarization in MERTK-Associated Retinal Degeneration.
    Invest Ophthalmol Vis Sci. 2025;66:1.
    PubMed     Abstract available


  8. ZHANG Y, Cao J, Zhang S, Wang S, et al
    Extracellular Matrix Stiffness Regulates Cancer Stemness in Uveal Melanoma via the PIEZO1-DOT1L Axis.
    Invest Ophthalmol Vis Sci. 2025;66:57.
    PubMed     Abstract available


    November 2025
  9. ASHWORTH KE, Zhang J, D'Amata C, Heon E, et al
    USH2A-Mutated Human Retinal Organoids Model Rod-Cone Dystrophy.
    Invest Ophthalmol Vis Sci. 2025;66:2.
    PubMed     Abstract available


  10. XU J, Gao Y, Wang J, Lyv M, et al
    GD2-CAR-Engineered Microglia Exhibit Antitumor Effects in Organoids and Animal Models of Retinoblastoma.
    Invest Ophthalmol Vis Sci. 2025;66:26.
    PubMed     Abstract available


    October 2025
  11. GEORGE A, Pfister T, DeYoung C, Sharma R, et al
    TYROSINASE-Deficient Human Retinal Pigment Epithelium Exhibits Melanosome Maturation Defects.
    Invest Ophthalmol Vis Sci. 2025;66:4.
    PubMed     Abstract available


  12. LI X, Yuan J, Chen Z, Zhang Y, et al
    Development of Two In Vitro ND1-LHON Models for Evaluating Gene Therapy Efficacy.
    Invest Ophthalmol Vis Sci. 2025;66:34.
    PubMed     Abstract available


    September 2025
  13. CHEN M, Jiang Y, Yu H, Qi H, et al
    Hydrogen Sulfide-Preconditioned Mesenchymal Stem Cells Attenuate Ferroptosis in Corneal Alkali Burn via the AMPK/Nrf2/HO-1 Pathway in an IL-10-Dependent Manner.
    Invest Ophthalmol Vis Sci. 2025;66:58.
    PubMed     Abstract available


  14. LI W, Li Y, Zhou Y, Liu Y, et al
    Exon Skipping Therapy Restores Ciliary Function in USH2A-Related Retinal Degeneration.
    Invest Ophthalmol Vis Sci. 2025;66:46.
    PubMed     Abstract available


  15. JIANG Y, Che Y, Zhang Y, Zhu X, et al
    Small Extracellular Vesicle Treatment of Trabecular Meshwork Fibrosis: 2D/3D In Vitro and In Vivo Analyses.
    Invest Ophthalmol Vis Sci. 2025;66:48.
    PubMed     Abstract available


    August 2025
  16. ALIO JL, Gauthier BR, Gomez Rosado JC, Alio Del Barrio JL, et al
    Human Omental Mesothelial Cells Exhibit a Corneal Endothelial-Like Cell Phenotype for Tissue Engineering of a Corneal Endothelium Biomimetic.
    Invest Ophthalmol Vis Sci. 2025;66:7.
    PubMed     Abstract available


    July 2025
  17. PICCOLO D, Sladen P, Guarascio R, Ziaka K, et al
    Investigation of ABCA4 Missense Variants and Potential Small Molecule Rescue in Retinal Organoids.
    Invest Ophthalmol Vis Sci. 2025;66:58.
    PubMed     Abstract available


  18. SCHIKORA J, Nickel A, Bergert J, Hahnel R, et al
    Complement C3 Activation in the Human Retinal Pigment Epithelium.
    Invest Ophthalmol Vis Sci. 2025;66:67.
    PubMed     Abstract available


    June 2025
  19. LI Y, Xie F, Yang L, Wang X, et al
    SLC6A6-Mediated Taurine Uptake Sustains Corneal Epithelial Stem/Progenitor Cell Function to Counteract Age-Related Dysfunction.
    Invest Ophthalmol Vis Sci. 2025;66:25.
    PubMed     Abstract available


  20. LANNING EP, Branch MJ, Harding P, Margari M, et al
    Characterization of Bruch's Membrane Formation in Human Fetal Retina and De Novo Membrane Synthesis by hPSC-Derived Retinal Pigment Epithelium.
    Invest Ophthalmol Vis Sci. 2025;66:40.
    PubMed     Abstract available


    May 2025
  21. LI Y, Liu Y
    Recent Advances in Stem Cells of Corneal Epithelia.
    Invest Ophthalmol Vis Sci. 2025;66:45.
    PubMed     Abstract available


    April 2025
  22. ZHAO L, Li N, Shi X, Zhang J, et al
    Enhanced Therapeutic Effect of IL-10-ADSCs on Rabbit Autoimmune Dacryoadenitis By Suppressing T Follicular Helper Cell Responses Via miR-142-5p/RC3H1 Axis.
    Invest Ophthalmol Vis Sci. 2025;66:66.
    PubMed     Abstract available


  23. WANG M, Chen R, Wang Y, Li Y, et al
    Expression Distribution of Keratins in Normal and Pathological Corneas and the Regulatory Role of Krt17 on Limbal Stem Cells.
    Invest Ophthalmol Vis Sci. 2025;66:55.
    PubMed     Abstract available


  24. WANG A, Li Z, Jiang Y, Chen M, et al
    Prox1 Protein in Corneal Limbal Lymphatic Vessels Maintains Limbal Stem Cell Stemness and Regulates Corneal Injury Repair.
    Invest Ophthalmol Vis Sci. 2025;66:81.
    PubMed     Abstract available


    March 2025
  25. JIANG D, Yu J, Wu X, Yu X, et al
    Isolated Mitochondrial Transplantation as a Novel Treatment for Corneal Chemical Burns.
    Invest Ophthalmol Vis Sci. 2025;66:14.
    PubMed     Abstract available


  26. LOU J, Huang H, Peng Y, Wang C, et al
    One-Month-Old Rabbits Exhibit a Longer Postoperative Remodeling in Extraocular Muscles Compared to 3-Month-Old Rabbits.
    Invest Ophthalmol Vis Sci. 2025;66:12.
    PubMed     Abstract available


  27. LI S, Sun H, Fang F, Zhang S, et al
    The Spatial Transcriptomic Atlas of Human Limbus and Vital Niche Microenvironment Regulating the Fate of Limbal Epithelial Stem Cells.
    Invest Ophthalmol Vis Sci. 2025;66:52.
    PubMed     Abstract available


    February 2025
  28. ZHOU X, Xu L, Tan Y, Wang W, et al
    Stiffness Regulates the Morphology and Stemness of Limbal Niche Cells Through Unique nYAP/cYAP Translocation.
    Invest Ophthalmol Vis Sci. 2025;66:43.
    PubMed     Abstract available


    January 2025
  29. SHEN Y, Wang J, Dai Y, Wan X, et al
    RSPO3 Promotes Proliferation and Self-Renewal of Limbal Epithelial Stem Cells Through a WNT/beta-Catenin-Independent Signaling Pathway.
    Invest Ophthalmol Vis Sci. 2025;66:8.
    PubMed     Abstract available


  30. XIAO Y, McGhee CNJ, Zhang J
    Posterior Limbal Mesenchymal Stromal Cells Promote Proliferation and Stemness of Transition Zone Cells: A Novel Insight Into Corneal Endothelial Rejuvenation.
    Invest Ophthalmol Vis Sci. 2025;66:44.
    PubMed     Abstract available


  31. WANG X, Wang X, Zhao Z, Wang Q, et al
    DNA-Dependent Protein Kinase Catalytic Subunit Prevents Ferroptosis in Retinal Pigment Epithelial Cells.
    Invest Ophthalmol Vis Sci. 2025;66:50.
    PubMed     Abstract available


    November 2024
  32. HAN J, Chear S, Talbot J, Swier V, et al
    Genetic and Cellular Basis of Impaired Phagocytosis and Photoreceptor Degeneration in CLN3 Disease.
    Invest Ophthalmol Vis Sci. 2024;65:23.
    PubMed     Abstract available


  33. LI Y, Ge L, Ren B, Zhang X, et al
    De-Differentiation of Corneal Epithelial Cells Into Functional Limbal Epithelial Stem Cells After the Ablation of Innate Stem Cells.
    Invest Ophthalmol Vis Sci. 2024;65:32.
    PubMed     Abstract available


    October 2024
  34. WANG G, Zhu Y, Liu Y, Yang M, et al
    Mesenchymal Stem Cells-Derived Exosomal miR-223-3p Alleviates Ocular Surface Damage and Inflammation by Downregulating Fbxw7 in Dry Eye Models.
    Invest Ophthalmol Vis Sci. 2024;65:1.
    PubMed     Abstract available


  35. GAO ML, Wang TY, Lin X, Tang C, et al
    Retinal Organoid Microenvironment Enhanced Bioactivities of Microglia-Like Cells Derived From HiPSCs.
    Invest Ophthalmol Vis Sci. 2024;65:19.
    PubMed     Abstract available


  36. AKIBA R, Tu HY, Hashiguchi T, Takahashi Y, et al
    Host-Graft Synapses Form Functional Microstructures and Shape the Host Light Responses After Stem Cell-Derived Retinal Sheet Transplantation.
    Invest Ophthalmol Vis Sci. 2024;65:8.
    PubMed     Abstract available


  37. ZHU L, Chen C, Wu S, Guo H, et al
    PAX6-WNK2 Axis Governs Corneal Epithelial Homeostasis.
    Invest Ophthalmol Vis Sci. 2024;65:40.
    PubMed     Abstract available


  38. KURIBAYASHI H, Iwagawa T, Murakami A, Kawamura T, et al
    NMNAT1 Is Essential for Human iPS Cell Differentiation to the Retinal Lineage.
    Invest Ophthalmol Vis Sci. 2024;65:37.
    PubMed     Abstract available


    September 2024
  39. RIZWAN S, Toothman B, Li B, Engel AJ, et al
    Metabolic Phenotyping of Healthy and Diseased Human RPE Cells.
    Invest Ophthalmol Vis Sci. 2024;65:5.
    PubMed     Abstract available


  40. CHOI YJ, Kim HM, Na TY, Park KH, et al
    Intraocular Concentration of Stem Cell Factor/c-KIT and Galectin-1 in Retinal Diseases.
    Invest Ophthalmol Vis Sci. 2024;65:11.
    PubMed     Abstract available


  41. DEVINE T, Elizondo G, Gaston G, Babcock SJ, et al
    iPSC-Derived LCHADD Retinal Pigment Epithelial Cells Are Susceptible to Lipid Peroxidation and Rescued by Transfection of a Wildtype AAV-HADHA Vector.
    Invest Ophthalmol Vis Sci. 2024;65:22.
    PubMed     Abstract available


    August 2024
  42. LI J, Ma J, Chen Y, Chen S, et al
    Biologically Relevant Laminin-511 Moderates the Derivation and Proliferation of Human Lens Epithelial Stem/Progenitor-Like Cells.
    Invest Ophthalmol Vis Sci. 2024;65:12.
    PubMed     Abstract available


  43. ZHOU H, Liu Y, Zhou T, Yang Z, et al
    IL-23 Priming Enhances the Neuroprotective Effects of MSC-Derived Exosomes in Treating Retinal Degeneration.
    Invest Ophthalmol Vis Sci. 2024;65:8.
    PubMed     Abstract available


  44. ASAI K, Lee HK, Sato S, Shimizu E, et al
    The Necroptosis Pathway Is Upregulated in the Cornea in Mice With Ocular Graft-Versus-Host Disease.
    Invest Ophthalmol Vis Sci. 2024;65:38.
    PubMed     Abstract available


    June 2024
  45. LIU J, Gao J, Lu P, Wang Y, et al
    Mesenchymal Stem Cell-Derived Exosomes as Drug Carriers for Delivering miRNA-29b to Ameliorate Inflammation in Corneal Injury Via Activating Autophagy.
    Invest Ophthalmol Vis Sci. 2024;65:16.
    PubMed     Abstract available


  46. SUN Y, Zhang Y, Shen J, Shi F, et al
    A Novel Murine Model for Lupus-Like Ocular Chronic Graft-Versus-Host Disease.
    Invest Ophthalmol Vis Sci. 2024;65:20.
    PubMed     Abstract available


    May 2024
  47. WIEBE-BEN ZAKOUR KE, Kaya S, Grumm L, Matros J, et al
    Modulation of Decellularized Lacrimal Gland Hydrogel Biodegradation by Genipin Crosslinking.
    Invest Ophthalmol Vis Sci. 2024;65:24.
    PubMed     Abstract available


    April 2024
  48. LIM RR, Shirali S, Rowlan J, Engel AL, et al
    CFH Haploinsufficiency and Complement Alterations in Early-Onset Macular Degeneration.
    Invest Ophthalmol Vis Sci. 2024;65:43.
    PubMed     Abstract available


    March 2024
  49. LEUNG J, Pollalis D, Nair GKG, Bailey JK, et al
    Isolation and Characterization of Extracellular Vesicles Through Orthogonal Approaches for the Development of Intraocular EV Therapy.
    Invest Ophthalmol Vis Sci. 2024;65:6.
    PubMed     Abstract available


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