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Articles published in PLoS Genet

Retrieve available abstracts of 79 articles:
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Single Articles


    January 2021
  1. TANG CY, Wu M, Zhao D, Edwards D, et al
    Runx1 is a central regulator of osteogenesis for bone homeostasis by orchestrating BMP and WNT signaling pathways.
    PLoS Genet. 2021;17:e1009233.
    PubMed     Abstract available


  2. LEHMAN BJ, Lopez-Diaz FJ, Santisakultarm TP, Fang L, et al
    Dynamic regulation of CTCF stability and sub-nuclear localization in response to stress.
    PLoS Genet. 2021;17:e1009277.
    PubMed     Abstract available


    December 2020
  3. LIN CY, Lu MJ, Yue JX, Li KL, et al
    Molecular asymmetry in the cephalochordate embryo revealed by single-blastomere transcriptome profiling.
    PLoS Genet. 2020;16:e1009294.
    PubMed     Abstract available


    November 2020
  4. GONZALEZ CURTO G, Der Vartanian A, Frarma YE, Manceau L, et al
    The PAX-FOXO1s trigger fast trans-differentiation of chick embryonic neural cells into alveolar rhabdomyosarcoma with tissue invasive properties limited by S phase entry inhibition.
    PLoS Genet. 2020;16:e1009164.
    PubMed     Abstract available


  5. CHIPPALKATTI R, Egger B, Suter B
    Mms19 promotes spindle microtubule assembly in Drosophila neural stem cells.
    PLoS Genet. 2020;16:e1008913.
    PubMed     Abstract available


    October 2020
  6. DAI Z, Li D, Du X, Ge Y, et al
    Drosophila Caliban preserves intestinal homeostasis and lifespan through regulating mitochondrial dynamics and redox state in enterocytes.
    PLoS Genet. 2020;16:e1009140.
    PubMed     Abstract available


  7. EVANO B, Gill D, Hernando-Herraez I, Comai G, et al
    Transcriptome and epigenome diversity and plasticity of muscle stem cells following transplantation.
    PLoS Genet. 2020;16:e1009022.
    PubMed     Abstract available


    September 2020
  8. GAZIOVA I, Gazi M, Mar J, Bhat KM, et al
    Restriction on self-renewing asymmetric division is coupled to terminal asymmetric division in the Drosophila CNS.
    PLoS Genet. 2020;16:e1009011.
    PubMed     Abstract available


  9. WEI H, Lambie EJ, Osorio DS, Carvalho AX, et al
    PIG-1 MELK-dependent phosphorylation of nonmuscle myosin II promotes apoptosis through CES-1 Snail partitioning.
    PLoS Genet. 2020;16:e1008912.
    PubMed     Abstract available


  10. LEVITAS A, Muhammad E, Zhang Y, Perea Gil I, et al
    A Novel Recessive Mutation in SPEG Causes Early Onset Dilated Cardiomyopathy.
    PLoS Genet. 2020;16:e1009000.
    PubMed     Abstract available


    August 2020
  11. BAKSHI A, Sipani R, Ghosh N, Joshi R, et al
    Sequential activation of Notch and Grainyhead gives apoptotic competence to Abdominal-B expressing larval neuroblasts in Drosophila Central nervous system.
    PLoS Genet. 2020;16:e1008976.
    PubMed     Abstract available


    June 2020
  12. MILLER CJ, Kim GY, Zhao X, Usdin K, et al
    All three mammalian MutL complexes are required for repeat expansion in a mouse cell model of the Fragile X-related disorders.
    PLoS Genet. 2020;16:e1008902.
    PubMed     Abstract available


    May 2020
  13. VON FRIELING J, Faisal MN, Sporn F, Pfefferkorn R, et al
    A high-fat diet induces a microbiota-dependent increase in stem cell activity in the Drosophila intestine.
    PLoS Genet. 2020;16:e1008789.
    PubMed     Abstract available


  14. JIANG S, Williams K, Kong X, Zeng W, et al
    Single-nucleus RNA-seq identifies divergent populations of FSHD2 myotube nuclei.
    PLoS Genet. 2020;16:e1008754.
    PubMed     Abstract available


    April 2020
  15. DING WY, Huang J, Wang H
    Waking up quiescent neural stem cells: Molecular mechanisms and implications in neurodevelopmental disorders.
    PLoS Genet. 2020;16:e1008653.
    PubMed     Abstract available


  16. CATINOZZI M, Mallik M, Frickenhaus M, Been M, et al
    The Drosophila FUS ortholog cabeza promotes adult founder myoblast selection by Xrp1-dependent regulation of FGF signaling.
    PLoS Genet. 2020;16:e1008731.
    PubMed     Abstract available


    March 2020
  17. HAMADA N, Hamazaki N, Shimamoto S, Hikabe O, et al
    Germ cell-intrinsic effects of sex chromosomes on early oocyte differentiation in mice.
    PLoS Genet. 2020;16:e1008676.
    PubMed     Abstract available


  18. CHEN J, Mohammad A, Pazdernik N, Huang H, et al
    GLP-1 Notch-LAG-1 CSL control of the germline stem cell fate is mediated by transcriptional targets lst-1 and sygl-1.
    PLoS Genet. 2020;16:e1008650.
    PubMed     Abstract available


    February 2020
  19. LINDSAY-MOSHER N, Chan A, Pearson BJ
    Planarian EGF repeat-containing genes megf6 and hemicentin are required to restrict the stem cell compartment.
    PLoS Genet. 2020;16:e1008613.
    PubMed     Abstract available


    January 2020
  20. LE V, He Y, Aldahl J, Hooker E, et al
    Loss of androgen signaling in mesenchymal sonic hedgehog responsive cells diminishes prostate development, growth, and regeneration.
    PLoS Genet. 2020;16:e1008588.
    PubMed     Abstract available


    December 2019
  21. ROJAS VILLA SE, Meng FW, Biteau B
    zfh2 controls progenitor cell activation and differentiation in the adult Drosophila intestinal absorptive lineage.
    PLoS Genet. 2019;15:e1008553.
    PubMed     Abstract available


    October 2019
  22. MADARO L, Torcinaro A, De Bardi M, Contino FF, et al
    Macrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx mice.
    PLoS Genet. 2019;15:e1008408.
    PubMed     Abstract available


    September 2019
  23. LIU N, Yin Y, Wang H, Zhou Z, et al
    Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling.
    PLoS Genet. 2019;15:e1008368.
    PubMed     Abstract available


    August 2019
  24. OKUYAMA K, Strid T, Kuruvilla J, Somasundaram R, et al
    PAX5 is part of a functional transcription factor network targeted in lymphoid leukemia.
    PLoS Genet. 2019;15:e1008280.
    PubMed     Abstract available


  25. WANG H, Guo S, Qiao X, Guo J, et al
    BZU2/ZmMUTE controls symmetrical division of guard mother cell and specifies neighbor cell fate in maize.
    PLoS Genet. 2019;15:e1008377.
    PubMed     Abstract available


    July 2019
  26. O'REILLY AM
    Irreversible effects of youthful choices in aged adults.
    PLoS Genet. 2019;15:e1008218.
    PubMed    


  27. CHANG YC, Tu H, Chen JY, Chang CC, et al
    Reproduction disrupts stem cell homeostasis in testes of aged male Drosophila via an induced microenvironment.
    PLoS Genet. 2019;15:e1008062.
    PubMed     Abstract available


    June 2019
  28. SCHREIBER C, Saraswati S, Harkins S, Gruber A, et al
    Loss of ASAP1 in mice impairs adipogenic and osteogenic differentiation of mesenchymal progenitor cells through dysregulation of FAK/Src and AKT signaling.
    PLoS Genet. 2019;15:e1008216.
    PubMed     Abstract available


  29. ANGULO B, Srinivasan S, Bolival BJ, Olivares GH, et al
    DREF Genetically Counteracts Mi-2 and Caf1 to Regulate Adult Stem Cell Maintenance.
    PLoS Genet. 2019;15:e1008187.
    PubMed     Abstract available


  30. TIAN A, Duwadi D, Benchabane H, Ahmed Y, et al
    Essential long-range action of Wingless/Wnt in adult intestinal compartmentalization.
    PLoS Genet. 2019;15:e1008111.
    PubMed     Abstract available


    May 2019
  31. SONG YC, Dohn TE, Rydeen AB, Nechiporuk AV, et al
    HDAC1-mediated repression of the retinoic acid-responsive gene ripply3 promotes second heart field development.
    PLoS Genet. 2019;15:e1008165.
    PubMed     Abstract available


  32. YAMADA M, Cai W, Martin LA, N'Tumba-Byn T, et al
    Functional robustness of adult spermatogonial stem cells after induction of hyperactive Hras.
    PLoS Genet. 2019;15:e1008139.
    PubMed     Abstract available


  33. SHIN H, Braendle C, Monahan KB, Kaplan REW, et al
    Developmental fidelity is imposed by genetically separable RalGEF activities that mediate opposing signals.
    PLoS Genet. 2019;15:e1008056.
    PubMed     Abstract available


  34. VAZQUEZ-ARREGUIN K, Bensard C, Schell JC, Swanson E, et al
    Oct1/Pou2f1 is selectively required for colon regeneration and regulates colon malignancy.
    PLoS Genet. 2019;15:e1007687.
    PubMed     Abstract available


  35. MESNER LD, Calabrese GM, Al-Barghouthi B, Gatti DM, et al
    Mouse genome-wide association and systems genetics identifies Lhfp as a regulator of bone mass.
    PLoS Genet. 2019;15:e1008123.
    PubMed     Abstract available


    April 2019
  36. JOSHI SS, Tandukar B, Pan L, Huang JM, et al
    CD34 defines melanocyte stem cell subpopulations with distinct regenerative properties.
    PLoS Genet. 2019;15:e1008034.
    PubMed     Abstract available


  37. SARKAR AK, Tung PY, Blischak JD, Burnett JE, et al
    Discovery and characterization of variance QTLs in human induced pluripotent stem cells.
    PLoS Genet. 2019;15:e1008045.
    PubMed     Abstract available


  38. AUDESSE AJ, Dhakal S, Hassell LA, Gardell Z, et al
    FOXO3 directly regulates an autophagy network to functionally regulate proteostasis in adult neural stem cells.
    PLoS Genet. 2019;15:e1008097.
    PubMed     Abstract available


  39. CHEN YC, Liao BK, Lu YF, Liu YH, et al
    Zebrafish Klf4 maintains the ionocyte progenitor population by regulating epidermal stem cell proliferation and lateral inhibition.
    PLoS Genet. 2019;15:e1008058.
    PubMed     Abstract available


    March 2019
  40. WANG L, Sloan MA, Ligoxygakis P
    Intestinal NF-kappaB and STAT signalling is important for uptake and clearance in a Drosophila-Herpetomonas interaction model.
    PLoS Genet. 2019;15:e1007931.
    PubMed     Abstract available


  41. GRIVE KJ, Hu Y, Shu E, Grimson A, et al
    Dynamic transcriptome profiles within spermatogonial and spermatocyte populations during postnatal testis maturation revealed by single-cell sequencing.
    PLoS Genet. 2019;15:e1007810.
    PubMed     Abstract available


  42. DING L, Shunkwiler LB, Harper NW, Zhao Y, et al
    Deletion of Cdkn1b in ACI rats leads to increased proliferation and pregnancy-associated changes in the mammary gland due to perturbed systemic endocrine environment.
    PLoS Genet. 2019;15:e1008002.
    PubMed     Abstract available


  43. HANDLEY MT, Reddy K, Wills J, Rosser E, et al
    ITPase deficiency causes a Martsolf-like syndrome with a lethal infantile dilated cardiomyopathy.
    PLoS Genet. 2019;15:e1007605.
    PubMed     Abstract available


    February 2019
  44. CAMARGO-SOSA K, Colanesi S, Muller J, Schulte-Merker S, et al
    Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependent pigment progenitors in zebrafish.
    PLoS Genet. 2019;15:e1007941.
    PubMed     Abstract available


  45. LI L, Ning G, Yang S, Yan Y, et al
    BMP signaling is required for nkx2.3-positive pharyngeal pouch progenitor specification in zebrafish.
    PLoS Genet. 2019;15:e1007996.
    PubMed     Abstract available


  46. DOHN TE, Ravisankar P, Tirera FT, Martin KE, et al
    Nr2f-dependent allocation of ventricular cardiomyocyte and pharyngeal muscle progenitors.
    PLoS Genet. 2019;15:e1007962.
    PubMed     Abstract available


    December 2018
  47. SCHMIDT D, Reuter H, Huttner K, Ruhe L, et al
    The Integrator complex regulates differential snRNA processing and fate of adult stem cells in the highly regenerative planarian Schmidtea mediterranea.
    PLoS Genet. 2018;14:e1007828.
    PubMed     Abstract available


  48. MENTINK RA, Rella L, Radaszkiewicz TW, Gybel T, et al
    The planar cell polarity protein VANG-1/Vangl negatively regulates Wnt/beta-catenin signaling through a Dvl dependent mechanism.
    PLoS Genet. 2018;14:e1007840.
    PubMed     Abstract available


    November 2018
  49. ABDULLAH C, Duronio RJ
    The many fates of tissue regeneration.
    PLoS Genet. 2018;14:e1007728.
    PubMed    


  50. VERGHESE S, Su TT
    Ionizing radiation induces stem cell-like properties in a caspase-dependent manner in Drosophila.
    PLoS Genet. 2018;14:e1007659.
    PubMed     Abstract available


  51. ANDRIATSILAVO M, Stefanutti M, Siudeja K, Perdigoto CN, et al
    Spen limits intestinal stem cell self-renewal.
    PLoS Genet. 2018;14:e1007773.
    PubMed     Abstract available


    October 2018
  52. PETRATOU K, Subkhankulova T, Lister JA, Rocco A, et al
    A systems biology approach uncovers the core gene regulatory network governing iridophore fate choice from the neural crest.
    PLoS Genet. 2018;14:e1007402.
    PubMed     Abstract available


    September 2018
  53. YE P, Chiang YJ, Qi Z, Li Y, et al
    Tankyrases maintain homeostasis of intestinal epithelium by preventing cell death.
    PLoS Genet. 2018;14:e1007697.
    PubMed     Abstract available


  54. HARA T, Maejima I, Akuzawa T, Hirai R, et al
    Rer1-mediated quality control system is required for neural stem cell maintenance during cerebral cortex development.
    PLoS Genet. 2018;14:e1007647.
    PubMed     Abstract available


    August 2018
  55. BOGUTZ AB, Oh-McGinnis R, Jacob KJ, Ho-Lau R, et al
    Transcription factor ASCL2 is required for development of the glycogen trophoblast cell lineage.
    PLoS Genet. 2018;14:e1007587.
    PubMed     Abstract available


    July 2018
  56. WILLIS NA, Panday A, Duffey EE, Scully R, et al
    Rad51 recruitment and exclusion of non-homologous end joining during homologous recombination at a Tus/Ter mammalian replication fork barrier.
    PLoS Genet. 2018;14:e1007486.
    PubMed     Abstract available


  57. MASTIO J, Simand C, Cova G, Kastner P, et al
    Ikaros cooperates with Notch activation and antagonizes TGFbeta signaling to promote pDC development.
    PLoS Genet. 2018;14:e1007485.
    PubMed     Abstract available


    May 2018
  58. CARMONA S, Lin B, Chou T, Arroyo K, et al
    LncRNA Jpx induces Xist expression in mice using both trans and cis mechanisms.
    PLoS Genet. 2018;14:e1007378.
    PubMed     Abstract available


  59. KITAMI K, Kitami M, Kaku M, Wang B, et al
    BRCA1 and BRCA2 tumor suppressors in neural crest cells are essential for craniofacial bone development.
    PLoS Genet. 2018;14:e1007340.
    PubMed     Abstract available


    April 2018
  60. SNIPES SA, Rodriguez K, DeVries AE, Miyawaki KN, et al
    Cytokinin stabilizes WUSCHEL by acting on the protein domains required for nuclear enrichment and transcription.
    PLoS Genet. 2018;14:e1007351.
    PubMed     Abstract available


    March 2018
  61. CHAN WL, Steiner M, Witkos T, Egerer J, et al
    Impaired proteoglycan glycosylation, elevated TGF-beta signaling, and abnormal osteoblast differentiation as the basis for bone fragility in a mouse model for gerodermia osteodysplastica.
    PLoS Genet. 2018;14:e1007242.
    PubMed     Abstract available


  62. BENNETT AH, O'Donohue MF, Gundry SR, Chan AT, et al
    RNA helicase, DDX27 regulates skeletal muscle growth and regeneration by modulation of translational processes.
    PLoS Genet. 2018;14:e1007226.
    PubMed     Abstract available


    February 2018
  63. FRESCHI A, Hur SK, Valente FM, Ideraabdullah FY, et al
    Tissue-specific and mosaic imprinting defects underlie opposite congenital growth disorders in mice.
    PLoS Genet. 2018;14:e1007243.
    PubMed     Abstract available


  64. HAGEY DW, Klum S, Kurtsdotter I, Zaouter C, et al
    SOX2 regulates common and specific stem cell features in the CNS and endoderm derived organs.
    PLoS Genet. 2018;14:e1007224.
    PubMed     Abstract available


  65. QIN Y, Sukumaran SK, Jyotaki M, Redding K, et al
    Gli3 is a negative regulator of Tas1r3-expressing taste cells.
    PLoS Genet. 2018;14:e1007058.
    PubMed     Abstract available


    January 2018
  66. DRAPER JE, Sroczynska P, Fadlullah MZH, Patel R, et al
    A novel prospective isolation of murine fetal liver progenitors to study in utero hematopoietic defects.
    PLoS Genet. 2018;14:e1007127.
    PubMed     Abstract available


  67. UPADHYAY M, Kuna M, Tudor S, Martino Cortez Y, et al
    A switch in the mode of Wnt signaling orchestrates the formation of germline stem cell differentiation niche in Drosophila.
    PLoS Genet. 2018;14:e1007154.
    PubMed     Abstract available


  68. STIELOW B, Finkernagel F, Stiewe T, Nist A, et al
    MGA, L3MBTL2 and E2F6 determine genomic binding of the non-canonical Polycomb repressive complex PRC1.6.
    PLoS Genet. 2018;14:e1007193.
    PubMed     Abstract available


  69. O'BRIEN LL, Guo Q, Bahrami-Samani E, Park JS, et al
    Transcriptional regulatory control of mammalian nephron progenitors revealed by multi-factor cistromic analysis and genetic studies.
    PLoS Genet. 2018;14:e1007181.
    PubMed     Abstract available


  70. MORRISON CA, Chen H, Cook T, Brown S, et al
    Glass promotes the differentiation of neuronal and non-neuronal cell types in the Drosophila eye.
    PLoS Genet. 2018;14:e1007173.
    PubMed     Abstract available


    December 2017
  71. SHIN H, Haupt KA, Kershner AM, Kroll-Conner P, et al
    SYGL-1 and LST-1 link niche signaling to PUF RNA repression for stem cell maintenance in Caenorhabditis elegans.
    PLoS Genet. 2017;13:e1007121.
    PubMed     Abstract available


  72. COLOMBO DF, Burger L, Baubec T, Schubeler D, et al
    Binding of high mobility group A proteins to the mammalian genome occurs as a function of AT-content.
    PLoS Genet. 2017;13:e1007102.
    PubMed     Abstract available


    November 2017
  73. HOUTZ P, Bonfini A, Liu X, Revah J, et al
    Hippo, TGF-beta, and Src-MAPK pathways regulate transcription of the upd3 cytokine in Drosophila enterocytes upon bacterial infection.
    PLoS Genet. 2017;13:e1007091.
    PubMed     Abstract available


  74. CHOI M, Genereux DP, Goodson J, Al-Azzawi H, et al
    Epigenetic memory via concordant DNA methylation is inversely correlated to developmental potential of mammalian cells.
    PLoS Genet. 2017;13:e1007060.
    PubMed     Abstract available


    October 2017
  75. QIN Y, Wu L, Ouyang Y, Zhou P, et al
    MiR-125a Is a critical modulator for neutrophil development.
    PLoS Genet. 2017;13:e1007027.
    PubMed     Abstract available


  76. SYRETT CM, Sindhava V, Hodawadekar S, Myles A, et al
    Loss of Xist RNA from the inactive X during B cell development is restored in a dynamic YY1-dependent two-step process in activated B cells.
    PLoS Genet. 2017;13:e1007050.
    PubMed     Abstract available


  77. ODHAMS CA, Cunninghame Graham DS, Vyse TJ
    Profiling RNA-Seq at multiple resolutions markedly increases the number of causal eQTLs in autoimmune disease.
    PLoS Genet. 2017;13:e1007071.
    PubMed     Abstract available


  78. GARG A, Bansal M, Gotoh N, Feng GS, et al
    Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis.
    PLoS Genet. 2017;13:e1007047.
    PubMed     Abstract available


    August 2017
  79. WEISSBEIN U, Plotnik O, Vershkov D, Benvenisty N, et al
    Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells.
    PLoS Genet. 2017;13:e1006979.
    PubMed     Abstract available


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