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By Bernd Sebastian Kamps and Andrea Melis

  Stem Cell Research

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Articles published in J Biol Chem

Retrieve available abstracts of 69 articles:
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Single Articles


    April 2026
  1. CORADIN M, Porter EG, Vitorino FN, Searfoss RM, et al
    Cleavage of histone H2A during embryonic stem cell differentiation destabilizes nucleosomes to counteract gene activation.
    J Biol Chem. 2026 Apr 9:111437. doi: 10.1016/j.jbc.2026.111437.
    PubMed     Abstract available


  2. ALHAMAD DW, Bensreti H, Ding K, Sultana S, et al
    Tryptophan metabolites 3-hydroxykynurenine (3HK) and 3-hydroxyanthranilic acid (3HAA) increase oxidative stress and impair osteoblastic bone formation.
    J Biol Chem. 2026;302:111174.
    PubMed     Abstract available


    March 2026
  3. LI X, Shen C, Li Y, Wu L, et al
    The RING E3 Ligase RLIM Drives Oxidative Stress-Induced Stem Cell Dysfunction through MDM2-p53 Signaling.
    J Biol Chem. 2026 Mar 20:111391. doi: 10.1016/j.jbc.2026.111391.
    PubMed     Abstract available


  4. SAITO A, Tankou S, Ishii K, Sakao-Suzuki M, et al
    Cytomegalovirus-encoded immediate early 1 protein perturbs neural progenitor proliferation via interfering with host PML-DISC1 interaction.
    J Biol Chem. 2026;302:111269.
    PubMed     Abstract available


  5. OBREBSKI T, Maleszewska M, Dunin-Horkawicz S, Malik AR, et al
    TET2 in epigenetic control of immune cells: Implications for inflammatory responses and age-related pathologies.
    J Biol Chem. 2026;302:111267.
    PubMed     Abstract available


  6. ZHAO Y, Fei Y, Cai Y, Wei Z, et al
    Multilineage differentiating stress-enduring cells alleviate neuropathic pain in mice through TGF-beta and IL-10-dependent anti-inflammatory signaling.
    J Biol Chem. 2026;302:111270.
    PubMed     Abstract available


  7. LI R, Pan K, Zhang Q, Guo Y, et al
    Alix-mediated selective packaging of beta-catenin into extracellular vesicles enhances their proangiogenic function.
    J Biol Chem. 2026;302:111254.
    PubMed     Abstract available


  8. BUI S, Reineberg A, Jones D, Na CL, et al
    Divergent pathways of surfactant protein C maturation for disease-associated isoforms.
    J Biol Chem. 2026;302:111252.
    PubMed     Abstract available


  9. JAMIL AJM, Norgard MO, Grupe E, Rauch A, et al
    Transcriptional plasticity of stromal cells amplifies their differentiation efficiency in vitro.
    J Biol Chem. 2026;302:111183.
    PubMed     Abstract available


  10. WESTOVER KR, Hou Y, Wang F, Wang Y, et al
    Loss of ATM causes R-loop-associated transcriptional dysregulation and attenuates the related response to DNA damage.
    J Biol Chem. 2026;302:111161.
    PubMed     Abstract available


    February 2026
  11. FU Y, Ma W, Han J, Zhang W, et al
    Topologically Associating Domains Define the 3D Genome Architecture of Mouse Totipotent-like Stem Cells.
    J Biol Chem. 2026 Feb 5:111236. doi: 10.1016/j.jbc.2026.111236.
    PubMed     Abstract available


    January 2026
  12. STOLARIK E, Zelek J, Thigpen M, Muller-Greven G, et al
    Inhibition of cell surface GRP78 on brain tumors reverses drug resistance and stops cancer stem cell expansion.
    J Biol Chem. 2026 Jan 12:111146. doi: 10.1016/j.jbc.2026.111146.
    PubMed     Abstract available


  13. XU X, Wei C, Zeng P, Zhan S, et al
    A-to-I RNA editing impairs miR-376b-3p repression of RYBP in skeletal muscle satellite cells.
    J Biol Chem. 2026;302:111006.
    PubMed     Abstract available


  14. GOHIL R, Gao Z, Lewis RA, Burkholder NT, et al
    HMGN1 and HMGN2 are recruited to acetylated and histone variant H2A.Z-containing nucleosomes to regulate chromatin state and transcription.
    J Biol Chem. 2026;302:110997.
    PubMed     Abstract available


    December 2025
  15. HAN Y, Gudmundsdottir B, Gudmundsson KO, Roy KR, et al
    The histone methyltransferase MLL1 complex inhibits expression of fetal hemoglobin.
    J Biol Chem. 2025;301:110863.
    PubMed     Abstract available


  16. MISHRA T, Giardine BM, Morrissey CS, Keller CA, et al
    Transcriptome and chromatin accessibility divergence during differentiation of a bipotential progenitor cell population to erythroblasts and megakaryocytes.
    J Biol Chem. 2025;301:110819.
    PubMed     Abstract available


  17. WU Y, Manna AK, Li L, Shen Z, et al
    Jade1 and the HBO1 histone acetyltransferase complex are spatial-selective cofactors of the pluripotency transcription factor Oct4.
    J Biol Chem. 2025;301:110859.
    PubMed     Abstract available


    October 2025
  18. ENOMOTO S, Hur YH, Solodova T, Neumann J, et al
    Embryonic stem cell-derived extracellular vesicles delay cellular senescence by inhibiting oxidative stress.
    J Biol Chem. 2025 Oct 14:110821. doi: 10.1016/j.jbc.2025.110821.
    PubMed     Abstract available


  19. KIM D, Li YZ, Yang J, Lin B, et al
    Platelet Jak2 deficiency accelerates atherosclerosis with increased inflammatory response.
    J Biol Chem. 2025;301:110603.
    PubMed     Abstract available


    September 2025
  20. FENG T, Rosen CJ, Li Z
    Omics Characteristics and Epigenetic Modifications of Adipose-Derived Stem Cells.
    J Biol Chem. 2025 Sep 24:110758. doi: 10.1016/j.jbc.2025.110758.
    PubMed     Abstract available


  21. ALI MM, Nookaew I, Resende-Coelho A, Marques-Carvalho A, et al
    Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells.
    J Biol Chem. 2025;301:110551.
    PubMed     Abstract available


  22. HANSEN BC, Arian CM, Zeng Y, Takezawa MG, et al
    Leveraging RNA-seq deconvolution to improve complex in vitro model characterization.
    J Biol Chem. 2025;301:110510.
    PubMed     Abstract available


    August 2025
  23. MORIKAWA M, Koinuma D, Sakai H, Kanda Y, et al
    SMAD1/5-Mediated Recruitment of the Histone Demethylase KDM1A Controls Cell Fate Programs in Embryonic Stem Cells.
    J Biol Chem. 2025 Aug 12:110591. doi: 10.1016/j.jbc.2025.110591.
    PubMed     Abstract available


  24. ALES E, Sackstein R
    Restricted human CD45 isoglycoforms serve as functional E-selectin ligands and delineate hematopoietic maturity.
    J Biol Chem. 2025;301:110431.
    PubMed     Abstract available


  25. YAMMINE KM, Mirda Abularach S, Xiong M, Kim SY, et al
    Failed cellular surveillance enables pathogenic matrix deposition in a COL2A1-related osteoarthritis.
    J Biol Chem. 2025;301:110436.
    PubMed     Abstract available


    July 2025
  26. LI M, Cao Y, Jin H, Wang A, et al
    The stage-specific roles of HIF-1alpha in regulating mESC pluripotency during oxygen transition.
    J Biol Chem. 2025;301:110344.
    PubMed     Abstract available


  27. LEGUAY K, Acevedo M, Colic E, Patel PU, et al
    Interactome of FMRP-N-tat therapeutic unveils key interactions for cellular function in Fragile X neurons.
    J Biol Chem. 2025;301:110341.
    PubMed     Abstract available


  28. SHIMADA M, Matsumoto Y, Otsuka K
    Live-cell imaging of DNA damage and cell cycle progression uncovers distinct responses during neural differentiation of hiPSCs.
    J Biol Chem. 2025;301:110328.
    PubMed     Abstract available


    June 2025
  29. YUAN X, Wu Y, Zhang Y, Yao B, et al
    Endocytosis of sialic acid Neu5Gc and elevated p53 contributes to preimplantation embryonic arrest during in vitro fertilization.
    J Biol Chem. 2025;301:110254.
    PubMed     Abstract available


  30. REN M, Chen S, Greenberg ML, Schlame M, et al
    ABHD18 degrades cardiolipin by stepwise hydrolysis of fatty acids.
    J Biol Chem. 2025;301:110237.
    PubMed     Abstract available


  31. QI Z, Luo J, Liu W, Xu Y, et al
    Alisertib impairs the stemness of hepatocellular carcinoma by inhibiting purine synthesis.
    J Biol Chem. 2025;301:108558.
    PubMed     Abstract available


  32. INOKI T, Tsuruta A, Masakado Y, Kai Y, et al
    N-acetyltransferase 10 promotes glioblastoma malignancy via mRNA stabilization of jumonji and AT-rich interaction domain containing 2.
    J Biol Chem. 2025;301:108544.
    PubMed     Abstract available


    May 2025
  33. MAJMUDAR PR, Keri RA
    The neural stem cell gene PAFAH1B1 controls cell cycle progression, DNA integrity, and paclitaxel sensitivity of triple-negative breast cancer cells.
    J Biol Chem. 2025 May 14:110235. doi: 10.1016/j.jbc.2025.110235.
    PubMed     Abstract available


  34. LI J, Li Z, Yin J, Wang Y, et al
    The sotos syndrome gene Nsd1 safeguards developmental gene enhancers poised for transcription by maintaining the precise deposition of histone methylation.
    J Biol Chem. 2025;301:108423.
    PubMed     Abstract available


    April 2025
  35. KARAKIS V, Britt JW, Jabeen M, San Miguel A, et al
    Derivation of human trophoblast stem cells from placentas at birth.
    J Biol Chem. 2025 Apr 10:108505. doi: 10.1016/j.jbc.2025.108505.
    PubMed     Abstract available


  36. QI M, Wang B, Liao H, Xu Y, et al
    Loss of sex-determining region Y-box 2 (SOX2) captures embryonic stem cells in a primed pluripotent state.
    J Biol Chem. 2025 Apr 9:108501. doi: 10.1016/j.jbc.2025.108501.
    PubMed     Abstract available


  37. WU X, Cai W, He J, Zhang S, et al
    YTHDF2 Suppresses the 2C-like State in Mouse Embryonic Stem Cells via the DUX-ZSCAN4 Molecular Circuit.
    J Biol Chem. 2025 Apr 4:108479. doi: 10.1016/j.jbc.2025.108479.
    PubMed     Abstract available


  38. SAKAI T, Kumagai K
    Molecular dissection of tendon development and healing: Insights into tenogenic phenotypes and functions.
    J Biol Chem. 2025;301:108353.
    PubMed     Abstract available


    March 2025
  39. XU X, Fu J, Yang G, Chen Z, et al
    Dentin sialoprotein promotes endothelial differentiation of dental pulp stem cells through DSP(aa34-50)-endoglin-AKT1 axis.
    J Biol Chem. 2025 Mar 4:108380. doi: 10.1016/j.jbc.2025.108380.
    PubMed     Abstract available


  40. MOOSHAYEF N, Gilad N, Mohanam MP, Engelberg D, et al
    Knocking out p38alpha+p38beta+p38gamma is required to abort the myogenic program in C2C12 myoblasts and to impose uncontrolled proliferation.
    J Biol Chem. 2025;301:108281.
    PubMed     Abstract available


  41. XU X, Fu J, Yang G, Chen Z, et al
    Dentin sialoprotein acts as an angiogenic factor through association with the membrane receptor endoglin.
    J Biol Chem. 2025;301:108279.
    PubMed     Abstract available


    January 2025
  42. YU M, Fei B, Chu S
    Targeting HNRNPA2B1 to Overcome Chemotherapy Resistance in Gastric Cancer Stem Cells: Mechanisms and Therapeutic Potential.
    J Biol Chem. 2025 Jan 25:108234. doi: 10.1016/j.jbc.2025.108234.
    PubMed     Abstract available


  43. LI W, Shi R, Gao Y, Wang X, et al
    CBX2 promotes cervical cancer cell proliferation and resistance to DNA-damaging treatment via maintaining cancer stemness.
    J Biol Chem. 2025 Jan 8:108170. doi: 10.1016/j.jbc.2025.108170.
    PubMed     Abstract available


  44. CATHELINE SE, Smith CO, McArthur M, Yu C, et al
    Energy metabolism in osteoprogenitors and osteoblasts: Role of the pentose phosphate pathway.
    J Biol Chem. 2025;301:108016.
    PubMed     Abstract available


    December 2024
  45. MA Z, Tan S, Lu R, Chen P, et al
    Interplay of Chromatin Remodeling BAF Complexes in Mouse Embryonic and Epiblast Stem Cell Conversion and Maintenance.
    J Biol Chem. 2024 Dec 25:108140. doi: 10.1016/j.jbc.2024.108140.
    PubMed     Abstract available


  46. NELSON HA, Mullins NA, Abell AN
    MAP3K4 signaling regulates HDAC6 and TRAF4 coexpression and stabilization in trophoblast stem cells(dagger).
    J Biol Chem. 2024 Dec 20:108116. doi: 10.1016/j.jbc.2024.108116.
    PubMed     Abstract available


  47. BADRALMAA Y, Natarajan V
    Aberrant Wnt/beta-catenin signaling in the mesenchymal stem cells of LZTFL1-depleted mice leads to increased adipogenesis, with implications for obesity.
    J Biol Chem. 2024 Dec 9:108057. doi: 10.1016/j.jbc.2024.108057.
    PubMed     Abstract available


  48. ROMERO B, Hoque P, Robinson KG, Lee SK, et al
    The circular RNA circNFIX regulates MEF2C expression in muscle satellite cells in spastic cerebral palsy.
    J Biol Chem. 2024;300:107987.
    PubMed     Abstract available


  49. PETERS A, Banine F, Yasuhara K, Hoffman A, et al
    Distinct chemical structures inhibit the CEMIP hyaluronidase and promote oligodendrocyte progenitor cell maturation.
    J Biol Chem. 2024;300:107916.
    PubMed     Abstract available


    November 2024
  50. MASCIALE V, Banchelli F, Grisendi G, Samarelli AV, et al
    The molecular features of lung cancer stem cells (LCSCs) in dedifferentiation process-driven epigenetic alterations.
    J Biol Chem. 2024 Nov 13:107994. doi: 10.1016/j.jbc.2024.107994.
    PubMed     Abstract available


  51. CHEN B, Jia M, Zhao G, Liu Y, et al
    STAG2 promotes naive-primed transition via activating Lin28a transcription in mouse embryonic stem cells.
    J Biol Chem. 2024 Nov 5:107958. doi: 10.1016/j.jbc.2024.107958.
    PubMed     Abstract available


  52. CAVALLINI C, Olivi E, Tassinari R, Ventura C, et al
    Mechanotransduction, cellular biophotonic activity, and signaling patterns for tissue regeneration.
    J Biol Chem. 2024;300:107847.
    PubMed     Abstract available


  53. MORISHIMA N, Ito Y
    Calpain-5 regulates muscle-specific protein expression and nuclear positioning during myoblast differentiation.
    J Biol Chem. 2024;300:107842.
    PubMed     Abstract available


  54. HU J, Yuan J, Shi Q, Guo X, et al
    Single-cell profiling identifies LIN28A mRNA targets in the mouse pluripotent-to-2C-like transition and somatic cell reprogramming.
    J Biol Chem. 2024;300:107824.
    PubMed     Abstract available


  55. BIEZEMAN H, Nubie M, Oburoglu L
    Hematopoietic cells emerging from hemogenic endothelium exhibit lineage-specific oxidative stress responses.
    J Biol Chem. 2024;300:107815.
    PubMed     Abstract available


    October 2024
  56. ZHAO J, Qian H, An Y, Chu L, et al
    PPARgamma and C/EBPalpha enable adipocyte differentiation upon inhibition of histone methyltransferase PRC2 in malignant tumors.
    J Biol Chem. 2024;300:107765.
    PubMed     Abstract available


    September 2024
  57. KOBROSSY L, Xu W, Zhang C, Feng W, et al
    Unraveling MLL1-fusion Leukemia: Epigenetic Revelations from an iPS Cell Point Mutation.
    J Biol Chem. 2024 Sep 27:107825. doi: 10.1016/j.jbc.2024.107825.
    PubMed     Abstract available


    August 2024
  58. DONG K, Chen F, Wang L, Lin C, et al
    iMSC exosome delivers hsa-mir-125b-5p and strengthens acidosis resilience through suppression of ASIC1 protein in cerebral ischemia-reperfusion.
    J Biol Chem. 2024;300:107568.
    PubMed     Abstract available


  59. BASU B, Karwatka M, China B, McKibbin M, et al
    Glycogen myophosphorylase loss causes increased dependence on glucose in iPSC-derived retinal pigment epithelium.
    J Biol Chem. 2024;300:107569.
    PubMed     Abstract available


  60. SEKINE M, Fujiwara M, Okamoto K, Ichida K, et al
    Significance and amplification methods of the purine salvage pathway in human brain cells.
    J Biol Chem. 2024;300:107524.
    PubMed     Abstract available


  61. ZHU D, Huang MF, Xu A, Gao X, et al
    Systematic transcriptome profiling of hPSC-derived osteoblasts unveils CORIN's mastery in governing osteogenesis through CEBPD modulation.
    J Biol Chem. 2024;300:107494.
    PubMed     Abstract available


    July 2024
  62. HU L, Huang W, Liu B, Eklund EA, et al
    In Fanconi Anemia, impaired accumulation of bone marrow neutrophils during emergency granulopoiesis induces hematopoietic stem cell stress.
    J Biol Chem. 2024 Jul 9:107548. doi: 10.1016/j.jbc.2024.107548.
    PubMed     Abstract available


    June 2024
  63. KADYROVA LY, Mieczkowski PA, Kadyrov FA
    MutLalpha suppresses error-prone DNA mismatch repair and preferentially protects noncoding DNA from mutations.
    J Biol Chem. 2024;300:107406.
    PubMed     Abstract available


  64. BAGINSKA U, Balagura G, Toonen RF, Verhage M, et al
    High-throughput assay for regulated secretion of neuropeptides in mouse and human neurons.
    J Biol Chem. 2024;300:107321.
    PubMed     Abstract available


  65. HENNING P, Westerlund A, Horkeby K, Lionikaite V, et al
    Vitamin A enhanced periosteal osteoclastogenesis is associated with increased number of tissue-derived macrophages/osteoclast progenitors.
    J Biol Chem. 2024;300:107308.
    PubMed     Abstract available


    April 2024
  66. NOOKAEW I, Xiong J, Onal M, Bustamante-Gomez C, et al
    Refining the identity of mesenchymal cell types associated with murine periosteal and endosteal bone.
    J Biol Chem. 2024;300:107158.
    PubMed     Abstract available


    March 2024
  67. LV Y, Li J, Yu S, Zhang Y, et al
    The splicing factor Prpf31 is required for hematopoietic stem and progenitor cell expansion during zebrafish embryogenesis.
    J Biol Chem. 2024;300:105772.
    PubMed     Abstract available


    October 2023
  68. CHOI J, Lee H
    NFIB-MLL1 complex is required for the stemness and Dlx5-dependent osteogenic differentiation of C3H10T1/2 mesenchymal stem cells.
    J Biol Chem. 2023;299:105193.
    PubMed     Abstract available


    September 2023
  69. SLEPAK TI, Guyot M, Walters W, Eichberg DG, et al
    Dual role of the adhesion G-protein coupled receptor ADRGE5/CD97 in glioblastoma invasion and proliferation.
    J Biol Chem. 2023;299:105105.
    PubMed     Abstract available


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