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Articles published in J Clin Invest

Retrieve available abstracts of 105 articles:
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Single Articles


    June 2026
  1. WEYAND CM, Goronzy JJ
    Immune responses in aging adults.
    J Clin Invest. 2026;136:e206227.
    PubMed     Abstract available


  2. ZHANG X, Liu X, Qiao Y, Rabata A, et al
    Activation of the impaired NAMPT/SIRT7/SOD2 axis restores alveolar progenitor cell renewal in idiopathic pulmonary fibrosis.
    J Clin Invest. 2026;136:e198031.
    PubMed     Abstract available


  3. WU W, Zhang P, Wang D, Wu X, et al
    Cancer stem cells synthesize proline to attenuate oxidative stress.
    J Clin Invest. 2026;136:e200775.
    PubMed     Abstract available


    May 2026
  4. TANAKA M, Kim NC, Draper I, Littel HR, et al
    Deficiency of muscular dystrophy-related gene JAG2 causes NOTCH signaling dysfunction in muscle stem cells.
    J Clin Invest. 2026 May 19:e198639. doi: 10.1172/JCI198639.
    PubMed     Abstract available


  5. KIM TW, Piao J, Bocchi VD, Koo SY, et al
    Modulation of WNT and FGF18 enhances yield and subtype identity of hPSC-derived midbrain dopamine neurons.
    J Clin Invest. 2026;136:e190954.
    PubMed     Abstract available


  6. BASAKIS P, Shih LK, Li J, Brat DJ, et al
    Uncovering a feedback loop in glioblastoma that reinforces stemness and immunosuppression.
    J Clin Invest. 2026;136:e205841.
    PubMed     Abstract available


  7. ZHOU F, Pang L, Liu Y, Khan F, et al
    Symbiotic exclusivity between CLOCK and TFPI2 drives stemness and immunosuppression in glioblastoma models.
    J Clin Invest. 2026;136:e199056.
    PubMed     Abstract available


  8. GHERARDINI J, Samra T, Gomez-Gomez T, Akhundlu A, et al
    Transient p53/p21 activation selectively protects healthy human hair follicles and their stem cells from chemotherapy.
    J Clin Invest. 2026;136:e174447.
    PubMed     Abstract available


  9. GU W, Wang X, Solmonson A, Cai L, et al
    l-2-Hydroxyglutarate impairs neuronal differentiation through epigenetic activation of MYC expression.
    J Clin Invest. 2026;136:e197010.
    PubMed     Abstract available


    April 2026
  10. ZHANG S, Liu J, Li Y, Wang Y, et al
    Physiological MplW514L expression in hematopoietic stem cell causes an essential thrombocythemia and progressive myelofibrosis.
    J Clin Invest. 2026 Apr 23:e199690. doi: 10.1172/JCI199690.
    PubMed     Abstract available


  11. MA X, Nettleford SK, Tian Y, Dawany N, et al
    TNFSF13 insufficiency disrupts human colonic epithelial cell growth and associated B cell dynamics.
    J Clin Invest. 2026;136:e186032.
    PubMed     Abstract available


  12. HOFBAUER LC, Rauner M
    Deconstructing senescence phenotypes in cells of the bone and bone marrow.
    J Clin Invest. 2026;136:e204645.
    PubMed     Abstract available


  13. DOOLITTLE ML, Froemming MN, Rowsey JL, Ruan M, et al
    Aged murine bone marrow myeloid and mesenchymal cells develop unique senescence phenotypes.
    J Clin Invest. 2026;136:e195772.
    PubMed     Abstract available


    March 2026
  14. SHI H, Yao H, Liu Y, Fan M, et al
    BM-derived mesenchymal stem cell microvesicles protect enteric neural precursor cells and alleviate diabetes-associated enteric neuropathy.
    J Clin Invest. 2026;136:e192437.
    PubMed     Abstract available


  15. LIAN C, Peng W, Su P, Ye Y, et al
    Notch1 O-GlcNAcylation drives tumor stemness and mechanoadaptation to a stiff microenvironment and promotes chordoma recurrence.
    J Clin Invest. 2026;136:e194378.
    PubMed     Abstract available


  16. DE STEFANO MA, Ambrosio R, Luongo C, Porcelli T, et al
    Type 2 deiodinase-dependent surge in thyroid hormone controls muscle stem cell quiescence and self-renewal.
    J Clin Invest. 2026 Mar 5:e194925. doi: 10.1172/JCI194925.
    PubMed     Abstract available


  17. SONG P, Chen C, Franchini R, Duong B, et al
    N-acetyl-l-leucine lowers alpha-synuclein levels and improves synaptic function in Parkinson's disease models.
    J Clin Invest. 2026;136:e196137.
    PubMed     Abstract available


  18. SUN R, Gao C, Lu RO
    Tumor-intrinsic chromatin programs enforce immune evasion in glioblastoma.
    J Clin Invest. 2026;136:e203222.
    PubMed     Abstract available


  19. ZHU X, John AJ, Kim S, Wang L, et al
    Alcohol use disorder-associated gene FNDC4 alters glutamatergic and GABAergic neurogenesis in neural organoids.
    J Clin Invest. 2026;136:e193204.
    PubMed     Abstract available


    February 2026
  20. MARTENS MJ, Dutta D, Yu Y, Rein LE, et al
    The BIOPREVENT machine-learning algorithm predicts chronic graft-versus-host disease and mortality risk using posttransplant biomarkers.
    J Clin Invest. 2026;136:e195228.
    PubMed     Abstract available


  21. KONISHI S, Enkhbayar K, Liu S, Miyashita N, et al
    TP53/TAU axis regulates microtubule bundling to control alveolar stem cell mediated regeneration.
    J Clin Invest. 2026 Feb 5:e194762. doi: 10.1172/JCI194762.
    PubMed     Abstract available


  22. CHEN S, Barajas S, Vemula S, Yang Y, et al
    Mutant p53 promotes clonal hematopoiesis by generating a chronic inflammatory microenvironment.
    J Clin Invest. 2025;136:e184285.
    PubMed     Abstract available


    January 2026
  23. WU Z, Li N, Luo Z, Chen Z, et al
    Corrigendum to Axon guidance cue SLIT2 regulates the murine skeletal stem cell niche through sympathetic innervation.
    J Clin Invest. 2026;136:e203674.
    PubMed    


  24. YUAN F, Wu X, Yuan H, Wang D, et al
    Glioblastoma stem cells resist cuproptosis with circadian variation of copper levels.
    J Clin Invest. 2026;136:e192599.
    PubMed     Abstract available


  25. WU H, Zhong X, Ma N, He Z, et al
    Selective disruption of RORgammat-CBFbeta interaction by IMU-935 prevents RORgammat-dependent Th17 autoimmunity but not thymocyte development.
    J Clin Invest. 2026;136:e185942.
    PubMed     Abstract available


    December 2025
  26. CHEN HC, Bang MF, Wang HH, Shpargel KB, et al
    UTX coordinates TCF1 and STAT3 to control progenitor CD8+ T cell fate in autoimmune diabetes.
    J Clin Invest. 2025 Dec 16:e196325. doi: 10.1172/JCI196325.
    PubMed     Abstract available


  27. LEUNG CON, Gurung S, Chung KPS, Leung RWH, et al
    Adipocyte-derived FABP4 promotes metabolism-associated steatotic liver-induced hepatocellular carcinoma by driving ITGB1-mediated beta-catenin activation.
    J Clin Invest. 2025;135:e182322.
    PubMed     Abstract available


  28. ADACHI Y, Chen W, Zhang C, Wang T, et al
    Targeting kinesin family member 20A sensitizes stem-like triple-negative breast cancer cells to standard chemotherapy.
    J Clin Invest. 2025;135:e182394.
    PubMed     Abstract available


  29. GU H, Weng L, Chen C, Hao X, et al
    Nonionotropic action of an acid-sensing ion channel inhibits leukemogenesis in the acidic bone marrow niche.
    J Clin Invest. 2025;135:e189051.
    PubMed     Abstract available


  30. WU Z, Li N, Luo Z, Chen Z, et al
    Expression of Concern for Axon guidance cue SLIT2 regulates the murine skeletal stem cell niche through sympathetic innervation.
    J Clin Invest. 2025;135:e202595.
    PubMed    


    November 2025
  31. KINCROSS H, Mo YA, Wang X, Chang L, et al
    Loss of FBXO11 establishes a stem cell program in acute myeloid leukemia by dysregulating LONP1.
    J Clin Invest. 2025 Nov 25:e181943. doi: 10.1172/JCI181943.
    PubMed     Abstract available


  32. LIN Y, Gu Q, Lu S, Pan Z, et al
    Corrigendum to Ruxolitinib improves hematopoietic regeneration by restoring mesenchymal stromal cell function in acute graft-versus-host disease.
    J Clin Invest. 2025;135:e200847.
    PubMed    


  33. TAMBRALLI A, Knight JS
    Neutrophils take center stage in VEXAS syndrome pathogenesis.
    J Clin Invest. 2025;135:e199299.
    PubMed     Abstract available


  34. DONG G, Liu J, Jin W, Zhou H, et al
    UBA1-depleted neutrophils disrupt immune homeostasis and induce VEXAS-like autoinflammatory disease in mice.
    J Clin Invest. 2025;135:e193011.
    PubMed     Abstract available


    October 2025
  35. SINGH B, Hossain MA, Liang XH, Fages J, et al
    Lnk Deficiency Enhances Translesion Synthesis to Alleviate Replication Stress and Promote Hematopoietic Stem Cell Fitness.
    J Clin Invest. 2025 Oct 30:e191713. doi: 10.1172/JCI191713.
    PubMed     Abstract available


  36. MULLIN C, Lin K, Choe E, Sha C, et al
    The hematopoietic stem cell MYB enhancer is essential and recurrently amplified during T-cell leukemogenesis.
    J Clin Invest. 2025 Oct 23:e187998. doi: 10.1172/JCI187998.
    PubMed     Abstract available


  37. MEI Y, Xu Y, Zhang X, Feng B, et al
    3D cultured human medium spiny neurons functionally integrate and rescue motor deficits in Huntington's disease mice.
    J Clin Invest. 2025;135:e187941.
    PubMed     Abstract available


  38. MO J, Anastasaki C, Chen Z, Shipman T, et al
    Corrigendum for Humanized neurofibroma model from induced pluripotent stem cells delineates tumor pathogenesis and developmental origins.
    J Clin Invest. 2025;135:e199700.
    PubMed    


  39. WU Z, Li N, Luo Z, Chen Z, et al
    Axon guidance cue SLIT2 regulates the murine skeletal stem cell niche through sympathetic innervation.
    J Clin Invest. 2025;135:e193014.
    PubMed     Abstract available


  40. DUVAL AJ, Seker-Polat F, Rogozinska M, Kinali M, et al
    SOX9 drives a stem-like transcriptional state and platinum resistance in high-grade serous ovarian cancer.
    J Clin Invest. 2025;135:e186467.
    PubMed     Abstract available


    September 2025
  41. PARK SH, Cheon DH, Kim YM, Choi Y, et al
    NFAT5 dictates crosstalk between intestinal epithelial regenerative capacity and microbiota in murine colitis models.
    J Clin Invest. 2025;135:e183093.
    PubMed     Abstract available


  42. JI L, Yan J, Losurdo NA, Wang H, et al
    Mutations in the spliceosomal gene SNW1 cause neurodevelopment disorders with microcephaly.
    J Clin Invest. 2025;135:e186119.
    PubMed     Abstract available


  43. YANG J, Jiang Z, Fitzgerald DC, Ma C, et al
    Retraction of Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis.
    J Clin Invest. 2025;135:e198608.
    PubMed    


  44. VIRGILIO E, Tielens S, Bonfield G, Nian FS, et al
    Recessive TMEM167A variants cause neonatal diabetes, microcephaly and epilepsy syndrome.
    J Clin Invest. 2025 Sep 9:e195756. doi: 10.1172/JCI195756.
    PubMed     Abstract available


  45. DENG Z, Law CS, Kurra S, Simchoni N, et al
    Activated STING in the thymic epithelium alters T cell development and selection leading to autoimmunity.
    J Clin Invest. 2025;135:e180252.
    PubMed     Abstract available


  46. ORAVECZ-WILSON K, Lauder E, Taylor A, Maneix L, et al
    Corrigendum to Autophagy differentially regulates tissue tolerance of distinct target organs in graft-versus-host disease models.
    J Clin Invest. 2025;135:e198274.
    PubMed    


    August 2025
  47. XU T, Heon-Roberts R, Moore T, Dubot P, et al
    Neuraminidase 1 secondary deficiency contributes to CNS pathology in neurological mucopolysaccharidoses via brain protein hypersialylation.
    J Clin Invest. 2025;135:e177430.
    PubMed     Abstract available


    July 2025
  48. SAKA S, Lu Z, Wang Y, Liu P, et al
    Chromatin factor YY1 controls fetal hematopoietic stem cell migration and engraftment in mice.
    J Clin Invest. 2025 Jul 29:e188140. doi: 10.1172/JCI188140.
    PubMed     Abstract available


  49. SHAO JS, Lai AC, Huang WC, Wu KC, et al
    Pulmonary fibroblast-derived stem cell factor promotes neutrophilic asthma by augmenting IL-17A production from ILC3s.
    J Clin Invest. 2025 Jul 17:e187372. doi: 10.1172/JCI187372.
    PubMed     Abstract available


  50. SINGH AK, Bernabucci M, Dvorak NM, Haghighijoo Z, et al
    Sensory neuron-expressed FGF13 controls nociceptive signaling in diabetic neuropathy models.
    J Clin Invest. 2025;135:e183749.
    PubMed     Abstract available


  51. HUGHES EP, Syage AR, Mirzaei Mehrabad E, Lane TE, et al
    OCA-B promotes pathogenic maturation of stem-like CD4+ T cells and autoimmune demyelination.
    J Clin Invest. 2025;135:e187862.
    PubMed     Abstract available


    June 2025
  52. TOMISHIMA SA, Kim DD, Porter N, Guha I, et al
    The E3 ubiquitin ligase Cul5 regulates hematopoietic stem cell function for steady-state hematopoiesis in mice.
    J Clin Invest. 2025 Jun 26:e180913. doi: 10.1172/JCI180913.
    PubMed     Abstract available


    May 2025
  53. D'ADDIO F, Amabile G, Assi E, Maestroni A, et al
    TMEM219 signaling promotes intestinal stem cell death and exacerbates colitis.
    J Clin Invest. 2025;135:e185783.
    PubMed     Abstract available


  54. SCHLEGEL N
    Promoting mucosal healing by targeting TMEM219-dependent intestinal epithelial stem cell defects in inflammatory bowel disease.
    J Clin Invest. 2025;135:e192640.
    PubMed     Abstract available


  55. HUANG Y, Xie X, Liu M, Zhang Y, et al
    Restoring mitochondrial function promotes hematopoietic reconstitution from cord blood following cryopreservation-related functional decline.
    J Clin Invest. 2025;135:e183607.
    PubMed     Abstract available


    April 2025
  56. GATTU AK, Tanzer M, Yaron-Barir TM, Johnson JL, et al
    Cell-intrinsic insulin signaling defects in human iPS cell-derived hepatocytes in type 2 diabetes.
    J Clin Invest. 2025;135:e183513.
    PubMed     Abstract available


  57. GAO C, Dai Y, Spezza PA, Boasiako P, et al
    Megakaryocytes transfer mitochondria to bone marrow mesenchymal stromal cells to lower platelet activation.
    J Clin Invest. 2025;135:e189801.
    PubMed     Abstract available


  58. KANG M, Choi J, Han J, Araki T, et al
    Aberrant ERK signaling in astrocytes impairs learning and memory in RASopathy-associated BRAF mutant mouse models.
    J Clin Invest. 2025;135:e176631.
    PubMed     Abstract available


    March 2025
  59. DELAFONTAINE S, Meyts I
    Oncostatin M silence and neopeptide: the value of exploring patients with rare inherited bone marrow failure.
    J Clin Invest. 2025;135:e190955.
    PubMed     Abstract available


    February 2025
  60. LI H, Liu P, Xu S, Li Y, et al
    FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging.
    J Clin Invest. 2025;135:e191424.
    PubMed    


  61. WEI W, Gao X, Qian J, Li L, et al
    Beclin 1 prevents ISG15-mediated cytokine storms to secure fetal hematopoiesis and survival.
    J Clin Invest. 2025;135:e177375.
    PubMed     Abstract available


    January 2025
  62. HAMAMOTO K, Zhu G, Lai Q, Lesperance J, et al
    HoxBlinc lncRNA reprograms CTCF-independent TADs to drive leukemic transcription and HSC dysregulation in NUP98-rearranged leukemia.
    J Clin Invest. 2025;135:e184743.
    PubMed     Abstract available


  63. CUI X, Hou L, Yan B, Liu J, et al
    Sex dimorphism in the mouse bone marrow niche regulates hematopoietic engraftment via sex-specific Kdm5c/Cxcl12 signaling.
    J Clin Invest. 2025 Jan 21:e182125. doi: 10.1172/JCI182125.
    PubMed     Abstract available


  64. GRIFFITH JW, Luster AD
    No bones about it: regulatory T cells promote fracture healing.
    J Clin Invest. 2025;135:e188368.
    PubMed     Abstract available


  65. LI J, Bai J, Pham VT, Hashimoto M, et al
    Loss of Cpt1a results in elevated glucose-fueled mitochondrial oxidative phosphorylation and defective hematopoietic stem cells.
    J Clin Invest. 2025 Jan 9:e184069. doi: 10.1172/JCI184069.
    PubMed     Abstract available


  66. CHEN S, Huang C, Li K, Cheng M, et al
    Tumor-initiating cells escape tumor immunity via CCL8 from tumor-associated macrophages in mice.
    J Clin Invest. 2025;135:e180893.
    PubMed     Abstract available


  67. CHEN YT, Jiang MM, Leynes C, Adeyeye M, et al
    ATRX silences Cartpt expression in osteoblastic cells during skeletal development.
    J Clin Invest. 2025;135:e163587.
    PubMed     Abstract available


  68. CAMPBELL K, Li Q
    Clonal hematopoiesis JAKs up plaque formation.
    J Clin Invest. 2025;135:e187529.
    PubMed     Abstract available


  69. WANG BZ, Morsink MA, Kim SW, Luo LJ, et al
    Cardiac fibroblast BAG3 regulates TGFBR2 signaling and fibrosis in dilated cardiomyopathy.
    J Clin Invest. 2025;135:e181630.
    PubMed     Abstract available


    December 2024
  70. SAARELA D, Lis P, Gomes S, Nirujogi RS, et al
    Tagless LysoIP for immunoaffinity enrichment of native lysosomes from clinical samples.
    J Clin Invest. 2024;135:e183592.
    PubMed     Abstract available


  71. DEFAMIE V, Aliar K, Sarkar S, Vyas F, et al
    Metalloproteinase inhibitors regulate biliary progenitor cells through sDLK1 in organoid models of liver injury.
    J Clin Invest. 2024;135:e164997.
    PubMed     Abstract available


  72. KIM Y, Kim SW, Saul D, Neyazi M, et al
    Regulation of sarcomere formation and function in the healthy heart requires a titin intronic enhancer.
    J Clin Invest. 2024;135:e183353.
    PubMed     Abstract available


  73. WU Q, Yu C, Yu F, Guo Y, et al
    Evi1 governs Kdm6b-mediated histone demethylation to regulate the Laptm4b-driven mTOR pathway in hematopoietic progenitor cells.
    J Clin Invest. 2024;134:e173403.
    PubMed     Abstract available


  74. PEACH T, Quattrocelli M
    The muscle stem cell case of Benjamin Button: rejuvenating muscle regenerative capacity through nutraceuticals.
    J Clin Invest. 2024;134:e185054.
    PubMed     Abstract available


  75. WANG Q, Hu T, Zhang Q, Zhang Y, et al
    Fusobacterium nucleatum promotes colorectal cancer through neogenesis of tumor stem cells.
    J Clin Invest. 2024 Dec 10:e181595. doi: 10.1172/JCI181595.
    PubMed     Abstract available


    November 2024
  76. NAYAK RC, Emberesh S, Trump LR, Wellendorf AM, et al
    G-CSF resistance of ELANE-mutant neutropenia depends on SERF1-containing truncated-neutrophil elastase aggregates.
    J Clin Invest. 2024;135:e177342.
    PubMed     Abstract available


  77. WANG S, Huang T, Wu Q, Yuan H, et al
    Lactate reprograms glioblastoma immunity through CBX3-regulated histone lactylation.
    J Clin Invest. 2024;134:e176851.
    PubMed     Abstract available


  78. ANCEL S, Michaud J, Migliavacca E, Jomard C, et al
    Nicotinamide and pyridoxine stimulate muscle stem cell expansion and enhance regenerative capacity during aging.
    J Clin Invest. 2024 Nov 12:e163648. doi: 10.1172/JCI163648.
    PubMed     Abstract available


  79. PALLAVICINI G, Moccia A, Iegiani G, Parolisi R, et al
    Modeling primary microcephaly with human brain organoids reveals fundamental roles of CIT kinase activity.
    J Clin Invest. 2024;134:e175435.
    PubMed     Abstract available


    October 2024
  80. LIU Q, Huang J, Ding H, Tao Y, et al
    Flavin-containing monooxygenase 2 confers cardioprotection in ischemia models through its disulfide bond catalytic activity.
    J Clin Invest. 2024;134:e177077.
    PubMed     Abstract available


  81. SINHA S, Callow BW, Farfel AP, Roy S, et al
    Breast cancers that disseminate to bone marrow acquire aggressive phenotypes through CX43-related tumor-stroma tunnels.
    J Clin Invest. 2024;134:e170953.
    PubMed     Abstract available


  82. GHOTBI E, Tchegnon E, Chen Z, Li S, et al
    Transcription factor KROX20 marks epithelial stem cells for hair follicle formation.
    J Clin Invest. 2024 Oct 3:e180160. doi: 10.1172/JCI180160.
    PubMed     Abstract available


  83. CHEN CL, Tsukamoto H, Liu JC, Kashiwabara C, et al
    Reciprocal regulation by TLR4 and TGF-beta in tumor-initiating stem-like cells.
    J Clin Invest. 2024;134:e186923.
    PubMed    


    September 2024
  84. YANG H, Ping X, Zhou J, Ailifeire H, et al
    Reversible cold-induced lens opacity in a hibernator reveals a molecular target for treating cataracts.
    J Clin Invest. 2024;134:e169666.
    PubMed     Abstract available


  85. LIU H, Zhao XF, Lu YN, Hayes LR, et al
    CRISPR/Cas13d targeting suppresses repeat-associated non-AUG translation of C9orf72 hexanucleotide repeat RNA.
    J Clin Invest. 2024;134:e179016.
    PubMed     Abstract available


  86. DESCHAMPS P, Wacheux M, Gosseye A, Morabito M, et al
    CXCL8 secreted by immature granulocytes inhibits WT hematopoiesis in chronic myelomonocytic leukemia.
    J Clin Invest. 2024;134:e180738.
    PubMed     Abstract available


  87. XING W, Feng H, Jiang B, Gao B, et al
    Itm2a expression marks periosteal skeletal stem cells that contribute to bone fracture healing.
    J Clin Invest. 2024;134:e176528.
    PubMed     Abstract available


    August 2024
  88. BORDENAVE J, Gajda D, Michonneau D, Vallet N, et al
    Deciphering bone marrow engraftment after allogeneic stem cell transplantation in humans using single cell analyses.
    J Clin Invest. 2024 Aug 29:e180331. doi: 10.1172/JCI180331.
    PubMed     Abstract available


  89. WALKER NM, Ibuki Y, McLinden AP, Misumi K, et al
    MNK-driven eIF4E phosphorylation regulates the fibrogenic transformation of mesenchymal cells and chronic lung allograft dysfunction.
    J Clin Invest. 2024;134:e168393.
    PubMed     Abstract available


  90. SRIDHAR A, DeSantiago J, Chen H, Pavel MA, et al
    Modulation of NOX2 causes obesity-mediated atrial fibrillation.
    J Clin Invest. 2024;134:e175447.
    PubMed     Abstract available


  91. SCHLEICHER WE, Hoag B, De Dominici M, DeGregori J, et al
    CHIP: a clonal odyssey of the bone marrow niche.
    J Clin Invest. 2024;134:e180068.
    PubMed     Abstract available


    July 2024
  92. WU K, Zhang Y, Yin-DeClue H, Sun K, et al
    A correctable immune niche for epithelial stem-cell reprogramming and post-viral lung diseases.
    J Clin Invest. 2024 Jul 25:e183092. doi: 10.1172/JCI183092.
    PubMed     Abstract available


    June 2024
  93. MAROM R, Song IW, Busse EC, Washington ME, et al
    The IFITM5 mutation in osteogenesis imperfecta type V is associated with an ERK/SOX9-dependent osteoprogenitor differentiation defect.
    J Clin Invest. 2024;134:e170369.
    PubMed     Abstract available


    May 2024
  94. SELGRADE DF, Fullenkamp DE, Chychula IA, Li B, et al
    Susceptibility to innate immune activation in genetically mediated myocarditis.
    J Clin Invest. 2024;134:e180254.
    PubMed     Abstract available


  95. SAUL D, Doolittle ML, Rowsey JL, Froemming MN, et al
    Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair.
    J Clin Invest. 2024;134:e179834.
    PubMed     Abstract available


  96. LEOW DM, Ng YK, Wang LC, Koh HW, et al
    Hepatocyte-intrinsic SMN deficiency drives metabolic dysfunction and liver steatosis in spinal muscular atrophy.
    J Clin Invest. 2024;134:e173702.
    PubMed     Abstract available


  97. LENARDIC A, Domenig SA, Zvick J, Bundschuh N, et al
    Generation of allogenic and xenogeneic functional muscle stem cells for intramuscular transplantation.
    J Clin Invest. 2024 May 7:e166998. doi: 10.1172/JCI166998.
    PubMed     Abstract available


    April 2024
  98. MOE A, Rayasam A, Sauber G, Shah RK, et al
    Type 2 cannabinoid receptor expression on microglial cells regulates neuroinflammation during graft versus host disease.
    J Clin Invest. 2024 Apr 25:e175205. doi: 10.1172/JCI175205.
    PubMed     Abstract available


  99. SONG X, Tiek D, Miki S, Huang T, et al
    RNA splicing analysis deciphers developmental hierarchies and reveals therapeutic targets in adult glioma.
    J Clin Invest. 2024;134:e173789.
    PubMed     Abstract available


  100. KEAN LS, Blazar BR
    Major breakthroughs in hematopoietic stem cell transplantation and future challenges in clinical implementation.
    J Clin Invest. 2024;134:e179944.
    PubMed    


  101. NORTH D, Chakraverty R
    The road to refractory graft-versus-host disease is paved with good intentions.
    J Clin Invest. 2024;134:e177728.
    PubMed     Abstract available


  102. ZHANG P, Fleming P, Andoniou CE, Waltner OG, et al
    IL-6-mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantation.
    J Clin Invest. 2024;134:e174184.
    PubMed     Abstract available


    March 2024
  103. MA H, Lu C, Ziegler J, Liu A, et al
    Absence of Stat1 in donor CD4+ T cells promotes the expansion of Tregs and reduces graft-versus-host disease in mice.
    J Clin Invest. 2024;134:e180350.
    PubMed    


  104. ORAVECZ-WILSON K, Lauder E, Taylor A, Maneix L, et al
    Autophagy differentially regulates tissue tolerance of distinct target organs in graft-versus-host disease models.
    J Clin Invest. 2024;134:e167369.
    PubMed     Abstract available


    January 2024
  105. LUO M, Bao L, Xue Y, Zhu M, et al
    ZMYND8 protects breast cancer stem cells against oxidative stress and ferroptosis through activation of NRF2.
    J Clin Invest. 2024;134:e171166.
    PubMed     Abstract available


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