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Articles published in J Clin Invest

Retrieve available abstracts of 49 articles:
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Single Articles


    January 2020
  1. DERTSCHNIG S, Evans P, Santos E Sousa P, Manzo T, et al
    Graft-versus-host disease reduces lymph node display of tissue-restricted self-antigens and promotes autoimmunity.
    J Clin Invest. 2020 Jan 9. pii: 133102. doi: 10.1172/JCI133102.
    PubMed     Text format     Abstract available


    December 2019
  2. R MATHEW N, Vinnakota JM, Apostolova P, Erny D, et al
    Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia.
    J Clin Invest. 2019 Dec 17. pii: 130272. doi: 10.1172/JCI130272.
    PubMed     Text format     Abstract available


    October 2019
  3. FATIMA S, Kamble SS, Dwivedi VP, Bhattacharya D, et al
    Mycobacterium tuberculosis Programs Mesenchymal Stem Cells to Establish Dormancy and Persistence.
    J Clin Invest. 2019 Oct 24. pii: 128043. doi: 10.1172/JCI128043.
    PubMed     Text format     Abstract available


  4. HIMBURG HA, Roos M, Fang T, Zhang Y, et al
    Chronic myelogenous leukemia stem cells require cell-autonomous pleiotrophin signaling.
    J Clin Invest. 2019 Oct 15. pii: 129061. doi: 10.1172/JCI129061.
    PubMed     Text format     Abstract available


    June 2019
  5. ABRAHAM A, Qiu S, Chacko BK, Li H, et al
    SIRT1 regulates metabolism and leukemogenic potential in CML stem cells.
    J Clin Invest. 2019;130.
    PubMed     Text format     Abstract available


    May 2019
  6. HU Y, Zhang M, Tian N, Li D, et al
    The antibiotic clofoctol suppresses glioma stem cell proliferation by activating KLF13.
    J Clin Invest. 2019;130.
    PubMed     Text format     Abstract available


  7. KARPOVA D, Rettig MP, Ritchey J, Cancilla D, et al
    Targeting VLA4 integrin and CXCR2 mobilizes serially repopulating hematopoietic stem cells.
    J Clin Invest. 2019;130.
    PubMed     Text format     Abstract available


  8. SOFI MH, Wu Y, Schutt SD, Dai M, et al
    Thioredoxin-1 confines T cell alloresponse and pathogenicity in graft-versus-host disease.
    J Clin Invest. 2019;130.
    PubMed     Text format     Abstract available


  9. FREDRICKS DN
    The gut microbiota and graft-versus-host disease.
    J Clin Invest. 2019;129:1808-1817.
    PubMed     Text format     Abstract available


    April 2019
  10. CHEN Z, Wang HW, Wang S, Fan L, et al
    USP9X deubiquitinates ALDH1A3 and maintains mesenchymal identity in glioblastoma stem cells.
    J Clin Invest. 2019;130.
    PubMed     Text format     Abstract available


    March 2019
  11. WACHSMUTH LP, Patterson MT, Eckhaus MA, Venzon DJ, et al
    Post-transplantation cyclophosphamide prevents graft-versus-host disease by inducing alloreactive T cell dysfunction and suppression.
    J Clin Invest. 2019;130.
    PubMed     Text format     Abstract available


    February 2019
  12. PIYA S, Mu H, Bhattacharya S, Lorenzi PL, et al
    BETP degradation simultaneously targets acute myelogenous leukemia stem cells and the microenvironment.
    J Clin Invest. 2019;130.
    PubMed     Text format     Abstract available


  13. TAN HX, Jegaskanda S, Juno JA, Esterbauer R, et al
    Subdominance and poor intrinsic immunogenicity limit humoral immunity targeting influenza HA stem.
    J Clin Invest. 2019;129:850-862.
    PubMed     Text format     Abstract available


    January 2019
  14. NALLE SC, Zuo L, Ong MLDM, Singh G, et al
    Graft-versus-host disease propagation depends on increased intestinal epithelial tight junction permeability.
    J Clin Invest. 2019 Jan 22. pii: 98554. doi: 10.1172/JCI98554.
    PubMed     Text format     Abstract available


    December 2018
  15. ANVERSA P, Kajstura J, Rota M, Leri A, et al
    Regenerating new heart with stem cells.
    J Clin Invest. 2018;128:5676.
    PubMed     Text format    


    November 2018
  16. WANG H, Georgakopoulou A, Psatha N, Li C, et al
    In vivo hematopoietic stem cell gene therapy ameliorates murine thalassemia intermedia.
    J Clin Invest. 2018 Nov 13. pii: 122836. doi: 10.1172/JCI122836.
    PubMed     Text format     Abstract available


    October 2018
  17. LI CJ, Xiao Y, Yang M, Su T, et al
    Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging.
    J Clin Invest. 2018 Oct 22. pii: 99044. doi: 10.1172/JCI99044.
    PubMed     Text format     Abstract available


  18. VUCKOVIC S, Minnie SA, Smith D, Gartlan KH, et al
    Bone marrow transplantation generates T cell-dependent control of myeloma in mice.
    J Clin Invest. 2018 Oct 9. pii: 98888. doi: 10.1172/JCI98888.
    PubMed     Text format     Abstract available


  19. KUMAR S, Wilkes DW, Samuel N, Blanco MA, et al
    DeltaNp63-driven recruitment of myeloid-derived suppressor cells promotes metastasis in triple-negative breast cancer.
    J Clin Invest. 2018 Oct 8. pii: 99673. doi: 10.1172/JCI99673.
    PubMed     Text format     Abstract available


    September 2018
  20. SHASTRI A, Choudhary G, Teixeira M, Gordon-Mitchell S, et al
    Antisense STAT3 inhibitor decreases viability of myelodysplastic and leukemic stem cells.
    J Clin Invest. 2018 Sep 25. pii: 120156. doi: 10.1172/JCI120156.
    PubMed     Text format     Abstract available


    August 2018
  21. MCDONALD-HYMAN C, Muller JT, Loschi M, Thangavelu G, et al
    The vimentin intermediate filament network restrains regulatory T-cell suppression of graft-versus-host disease.
    J Clin Invest. 2018 Aug 14. pii: 95713. doi: 10.1172/JCI95713.
    PubMed     Text format     Abstract available


  22. ZHAO D, Kim YH, Jeong S, Greenson JK, et al
    Survival signal REG3-alpha prevents crypt apoptosis to control acute gastrointestinal graft-versus-host disease.
    J Clin Invest. 2018 Aug 14. pii: 99261. doi: 10.1172/JCI99261.
    PubMed     Text format     Abstract available


  23. WATKINS BK, Tkachev V, Furlan SN, Hunt DJ, et al
    CD28 blockade controls T cell activation to prevent graft-versus-host disease in primates.
    J Clin Invest. 2018 Aug 13. pii: 98793. doi: 10.1172/JCI98793.
    PubMed     Text format     Abstract available


    July 2018
  24. KABIRI Z, Greicius G, Zaribafzadeh H, Hemmerich A, et al
    Wnt signaling suppresses MAPK-driven proliferation of intestinal stem cells.
    J Clin Invest. 2018 Jul 30. pii: 99325. doi: 10.1172/JCI99325.
    PubMed     Text format     Abstract available


    June 2018
  25. BROXMEYER HE
    Enhancement of stem cell engraftment on a WHIM.
    J Clin Invest. 2018 Jun 25. pii: 121857. doi: 10.1172/JCI121857.
    PubMed     Text format     Abstract available


  26. ASOSINGH K, Weiss K, Queisser K, Wanner N, et al
    Endothelial cells in the innate response to allergens and initiation of atopic asthma.
    J Clin Invest. 2018 Jun 18. pii: 97720. doi: 10.1172/JCI97720.
    PubMed     Text format     Abstract available


  27. LIAO CM, Mukherjee S, Tiyaboonchai A, Maguire JA, et al
    GATA6 suppression enhances lung specification from human pluripotent stem cells.
    J Clin Invest. 2018 Jun 11. pii: 96539. doi: 10.1172/JCI96539.
    PubMed     Text format     Abstract available


    May 2018
  28. GAO JL, Yim E, Siwicki M, Yang A, et al
    Cxcr4-haploinsufficient bone marrow transplantation corrects leukopenia in an unconditioned WHIM syndrome model.
    J Clin Invest. 2018 May 1. pii: 120375. doi: 10.1172/JCI120375.
    PubMed     Text format     Abstract available


    January 2018
  29. ULLRICH E, Abendroth B, Rothamer J, Huber C, et al
    BATF-dependent IL-7RhiGM-CSF+ T cells control intestinal graft-versus-host disease.
    J Clin Invest. 2018 Jan 29. pii: 89242. doi: 10.1172/JCI89242.
    PubMed     Text format     Abstract available


    December 2017
  30. TSAI RY
    Creating a graft-friendly environment for stem cells in diseased brains.
    J Clin Invest. 2017 Dec 11. pii: 98490. doi: 10.1172/JCI98490.
    PubMed     Text format     Abstract available


  31. SUN Q, Lesperance J, Wettersten H, Luterstein E, et al
    Proapoptotic PUMA targets stem-like breast cancer cells to suppress metastasis.
    J Clin Invest. 2017 Dec 11. pii: 93707. doi: 10.1172/JCI93707.
    PubMed     Text format     Abstract available


    November 2017
  32. DE FEO D, Merlini A, Brambilla E, Ottoboni L, et al
    Neural precursor cell-secreted TGF-beta2 redirects inflammatory monocyte-derived cells in CNS autoimmunity.
    J Clin Invest. 2017;127:3937-3953.
    PubMed     Text format     Abstract available


    October 2017
  33. POULOS MG, Ramalingam P, Gutkin MC, Llanos P, et al
    Endothelial transplantation rejuvenates aged hematopoietic stem cell function.
    J Clin Invest. 2017 Oct 16. pii: 93940. doi: 10.1172/JCI93940.
    PubMed     Text format     Abstract available


  34. COLE CB, Russler-Germain DA, Ketkar S, Verdoni AM, et al
    Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies.
    J Clin Invest. 2017;127:3657-3674.
    PubMed     Text format     Abstract available


  35. TARNAWSKY SP, Chan RJ, Yoder MC
    Mice expressing KrasG12D in hematopoietic multipotent progenitor cells develop neonatal myeloid leukemia.
    J Clin Invest. 2017;127:3652-3656.
    PubMed     Text format     Abstract available


    September 2017
  36. PHILIPS T, Rothstein JD
    Oligodendroglia: metabolic supporters of neurons.
    J Clin Invest. 2017;127:3271-3280.
    PubMed     Text format     Abstract available


  37. KURODA M, Muramatsu R, Maedera N, Koyama Y, et al
    Peripherally derived FGF21 promotes remyelination in the central nervous system.
    J Clin Invest. 2017;127:3496-3509.
    PubMed     Text format     Abstract available


  38. YUAN H, Li N, Fu D, Ren J, et al
    Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis.
    J Clin Invest. 2017;127:3375-3391.
    PubMed     Text format     Abstract available


  39. HINO K, Horigome K, Nishio M, Komura S, et al
    Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva.
    J Clin Invest. 2017;127:3339-3352.
    PubMed     Text format     Abstract available


  40. GOLDMAN SA
    Patience pays in spinal repair.
    J Clin Invest. 2017;127:3284-3286.
    PubMed     Text format     Abstract available


    August 2017
  41. WANG J, Cheng P, Pavlyukov MS, Yu H, et al
    Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2.
    J Clin Invest. 2017;127:3075-3089.
    PubMed     Text format     Abstract available


    June 2017
  42. MATTE-MARTONE C, Liu J, Zhou M, Chikina M, et al
    Differential requirements for myeloid leukemia IFN-gamma conditioning determine graft-versus-leukemia resistance and sensitivity.
    J Clin Invest. 2017;127:2765-2776.
    PubMed     Text format     Abstract available


  43. XIA H, Gilbertsen A, Herrera J, Racila E, et al
    Calcium-binding protein S100A4 confers mesenchymal progenitor cell fibrogenicity in idiopathic pulmonary fibrosis.
    J Clin Invest. 2017;127:2586-2597.
    PubMed     Text format     Abstract available


  44. GIROUX V, Lento AA, Islam M, Pitarresi JR, et al
    Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration.
    J Clin Invest. 2017;127:2378-2391.
    PubMed     Text format     Abstract available


  45. ELAGIB KE, Lu CH, Mosoyan G, Khalil S, et al
    Neonatal expression of RNA-binding protein IGF2BP3 regulates the human fetal-adult megakaryocyte transition.
    J Clin Invest. 2017;127:2365-2377.
    PubMed     Text format     Abstract available


  46. NIEBOROWSKA-SKORSKA M, Sullivan K, Dasgupta Y, Podszywalow-Bartnicka P, et al
    Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells.
    J Clin Invest. 2017;127:2392-2406.
    PubMed     Text format     Abstract available


  47. GASKILL CF, Carrier EJ, Kropski JA, Bloodworth NC, et al
    Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction.
    J Clin Invest. 2017;127:2262-2276.
    PubMed     Text format     Abstract available


    May 2017
  48. HEBBEL RP
    Blood endothelial cells: utility from ambiguity.
    J Clin Invest. 2017;127:1613-1615.
    PubMed     Text format     Abstract available


    April 2017
  49. TEVERONI E, Pellegrino M, Sacconi S, Calandra P, et al
    Estrogens enhance myoblast differentiation in facioscapulohumeral muscular dystrophy by antagonizing DUX4 activity.
    J Clin Invest. 2017;127:1531-1545.
    PubMed     Text format     Abstract available


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