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Articles published in Nat Genet

Retrieve available abstracts of 61 articles:
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    April 2021
  1. BIRLING MC, Yoshiki A, Adams DJ, Ayabe S, et al
    A resource of targeted mutant mouse lines for 5,061 genes.
    Nat Genet. 2021;53:416-419.
    PubMed    


  2. CHIOU J, Zeng C, Cheng Z, Han JY, et al
    Single-cell chromatin accessibility identifies pancreatic islet cell type- and state-specific regulatory programs of diabetes risk.
    Nat Genet. 2021;53:455-466.
    PubMed     Abstract available


  3. GOKHMAN D, Agoglia RM, Kinnebrew M, Gordon W, et al
    Human-chimpanzee fused cells reveal cis-regulatory divergence underlying skeletal evolution.
    Nat Genet. 2021;53:467-476.
    PubMed     Abstract available


  4. LIU N, Xu S, Yao Q, Zhu Q, et al
    Transcription factor competition at the gamma-globin promoters controls hemoglobin switching.
    Nat Genet. 2021;53:511-520.
    PubMed     Abstract available


    March 2021
  5. BONDER MJ, Smail C, Gloudemans MJ, Fresard L, et al
    Identification of rare and common regulatory variants in pluripotent cells using population-scale transcriptomics.
    Nat Genet. 2021;53:313-321.
    PubMed     Abstract available


  6. JERBER J, Seaton DD, Cuomo ASE, Kumasaka N, et al
    Population-scale single-cell RNA-seq profiling across dopaminergic neuron differentiation.
    Nat Genet. 2021;53:304-312.
    PubMed     Abstract available


  7. KITAZAWA T, Machlab D, Joshi O, Maiorano N, et al
    A unique bipartite Polycomb signature regulates stimulus-response transcription during development.
    Nat Genet. 2021;53:379-391.
    PubMed     Abstract available


  8. AVSEC Z, Weilert M, Shrikumar A, Krueger S, et al
    Base-resolution models of transcription-factor binding reveal soft motif syntax.
    Nat Genet. 2021;53:354-366.
    PubMed     Abstract available


  9. IURLARO M, Stadler MB, Masoni F, Jagani Z, et al
    Mammalian SWI/SNF continuously restores local accessibility to chromatin.
    Nat Genet. 2021;53:279-287.
    PubMed     Abstract available


    February 2021
  10. WOO XY, Giordano J, Srivastava A, Zhao ZM, et al
    Author Correction: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts.
    Nat Genet. 2021 Feb 19. pii: 10.1038/s41588-021-00811.
    PubMed    


  11. BETTO RM, Diamante L, Perrera V, Audano M, et al
    Metabolic control of DNA methylation in naive pluripotent cells.
    Nat Genet. 2021;53:215-229.
    PubMed     Abstract available


  12. LAFFLEUR B, Lim J, Zhang W, Chen Y, et al
    Noncoding RNA processing by DIS3 regulates chromosomal architecture and somatic hypermutation in B cells.
    Nat Genet. 2021;53:230-242.
    PubMed     Abstract available


    January 2021
  13. WOO XY, Giordano J, Srivastava A, Zhao ZM, et al
    Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts.
    Nat Genet. 2021;53:86-99.
    PubMed     Abstract available


  14. LIU NQ, Maresca M, van den Brand T, Braccioli L, et al
    WAPL maintains a cohesin loading cycle to preserve cell-type-specific distal gene regulation.
    Nat Genet. 2021;53:100-109.
    PubMed     Abstract available


    December 2020
  15. FASCIANI A, D'Annunzio S, Poli V, Fagnocchi L, et al
    MLL4-associated condensates counterbalance Polycomb-mediated nuclear mechanical stress in Kabuki syndrome.
    Nat Genet. 2020;52:1397-1411.
    PubMed     Abstract available


    November 2020
  16. SZABO Q, Donjon A, Jerkovic I, Papadopoulos GL, et al
    Regulation of single-cell genome organization into TADs and chromatin nanodomains.
    Nat Genet. 2020;52:1151-1157.
    PubMed     Abstract available


    October 2020
  17. MADSEN JGS, Madsen MS, Rauch A, Traynor S, et al
    Highly interconnected enhancer communities control lineage-determining genes in human mesenchymal stem cells.
    Nat Genet. 2020 Oct 5. pii: 10.1038/s41588-020-0709.
    PubMed     Abstract available


    September 2020
  18. MOCAVINI I, Di Croce L
    RNA closing the Polycomb circle.
    Nat Genet. 2020;52:866-867.
    PubMed    


  19. GUO W, Li L, He J, Liu Z, et al
    Single-cell transcriptomics identifies a distinct luminal progenitor cell type in distal prostate invagination tips.
    Nat Genet. 2020;52:908-918.
    PubMed     Abstract available


    August 2020
  20. CHARLTON J, Jung EJ, Mattei AL, Bailly N, et al
    TETs compete with DNMT3 activity in pluripotent cells at thousands of methylated somatic enhancers.
    Nat Genet. 2020;52:819-827.
    PubMed     Abstract available


    July 2020
  21. LONG Y, Hwang T, Gooding AR, Goodrich KJ, et al
    RNA is essential for PRC2 chromatin occupancy and function in human pluripotent stem cells.
    Nat Genet. 2020 Jul 6. pii: 10.1038/s41588-020-0662.
    PubMed     Abstract available


    June 2020
  22. DOUILLET D, Sze CC, Ryan C, Piunti A, et al
    Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation.
    Nat Genet. 2020;52:615-625.
    PubMed     Abstract available


    April 2020
  23. CHOUDHURY AR, Ju Z, Djojosubroto MW, Schienke A, et al
    Author Correction: Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation.
    Nat Genet. 2020 Apr 30. pii: 10.1038/s41588-020-0593.
    PubMed     Abstract available


  24. IZZO F, Lee SC, Poran A, Chaligne R, et al
    DNA methylation disruption reshapes the hematopoietic differentiation landscape.
    Nat Genet. 2020;52:378-387.
    PubMed     Abstract available


  25. FERNANDO MB, Ahfeldt T, Brennand KJ
    Modeling the complex genetic architectures of brain disease.
    Nat Genet. 2020;52:363-369.
    PubMed     Abstract available


    March 2020
  26. GEHRE M, Bunina D, Sidoli S, Lubke MJ, et al
    Lysine 4 of histone H3.3 is required for embryonic stem cell differentiation, histone enrichment at regulatory regions and transcription accuracy.
    Nat Genet. 2020;52:273-282.
    PubMed     Abstract available


  27. NGAN CY, Wong CH, Tjong H, Wang W, et al
    Chromatin interaction analyses elucidate the roles of PRC2-bound silencers in mouse development.
    Nat Genet. 2020;52:264-272.
    PubMed     Abstract available


    January 2020
  28. ABAKIR A, Giles TC, Cristini A, Foster JM, et al
    N(6)-methyladenosine regulates the stability of RNA:DNA hybrids in human cells.
    Nat Genet. 2020;52:48-55.
    PubMed     Abstract available


  29. XIANG Y, Zhang Y, Xu Q, Zhou C, et al
    Epigenomic analysis of gastrulation identifies a unique chromatin state for primed pluripotency.
    Nat Genet. 2020;52:95-105.
    PubMed     Abstract available


    December 2019
  30. FLAHERTY E, Zhu S, Barretto N, Cheng E, et al
    Neuronal impact of patient-specific aberrant NRXN1alpha splicing.
    Nat Genet. 2019;51:1679-1690.
    PubMed     Abstract available


    November 2019
  31. ALMENAR-QUERALT A, Merkurjev D, Kim HS, Navarro M, et al
    Chromatin establishes an immature version of neuronal protocadherin selection during the naive-to-primed conversion of pluripotent stem cells.
    Nat Genet. 2019 Nov 18. pii: 10.1038/s41588-019-0526.
    PubMed     Abstract available


  32. DWIVEDI OP, Lehtovirta M, Hastoy B, Chandra V, et al
    Loss of ZnT8 function protects against diabetes by enhanced insulin secretion.
    Nat Genet. 2019 Nov 1. pii: 10.1038/s41588-019-0513.
    PubMed     Abstract available


    October 2019
  33. BENAGLIO P, D'Antonio-Chronowska A, Ma W, Yang F, et al
    Allele-specific NKX2-5 binding underlies multiple genetic associations with human electrocardiographic traits.
    Nat Genet. 2019;51:1506-1517.
    PubMed     Abstract available


  34. NACHMANI D, Bothmer AH, Grisendi S, Mele A, et al
    Germline NPM1 mutations lead to altered rRNA 2'-O-methylation and cause dyskeratosis congenita.
    Nat Genet. 2019;51:1518-1529.
    PubMed     Abstract available


    September 2019
  35. SCHRODE N, Ho SM, Yamamuro K, Dobbyn A, et al
    Synergistic effects of common schizophrenia risk variants.
    Nat Genet. 2019 Sep 23. pii: 10.1038/s41588-019-0497.
    PubMed     Abstract available


  36. MIURA H, Takahashi S, Poonperm R, Tanigawa A, et al
    Single-cell DNA replication profiling identifies spatiotemporal developmental dynamics of chromosome organization.
    Nat Genet. 2019;51:1356-1368.
    PubMed     Abstract available


    August 2019
  37. ZHANG Y, Li T, Preissl S, Amaral ML, et al
    Transcriptionally active HERV-H retrotransposons demarcate topologically associating domains in human pluripotent stem cells.
    Nat Genet. 2019 Aug 19. pii: 10.1038/s41588-019-0479.
    PubMed     Abstract available


  38. SONG M, Yang X, Ren X, Maliskova L, et al
    Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes.
    Nat Genet. 2019;51:1252-1262.
    PubMed     Abstract available


    June 2019
  39. MARTIRE S, Gogate AA, Whitmill A, Tafessu A, et al
    Phosphorylation of histone H3.3 at serine 31 promotes p300 activity and enhancer acetylation.
    Nat Genet. 2019;51:941-946.
    PubMed     Abstract available


  40. VAN BEMMEL JG, Galupa R, Gard C, Servant N, et al
    The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist.
    Nat Genet. 2019;51:1024-1034.
    PubMed     Abstract available


  41. LI QV, Dixon G, Verma N, Rosen BP, et al
    Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation.
    Nat Genet. 2019;51:999-1010.
    PubMed     Abstract available


    May 2019
  42. PAULSEN J, Liyakat Ali TM, Nekrasov M, Delbarre E, et al
    Long-range interactions between topologically associating domains shape the four-dimensional genome during differentiation.
    Nat Genet. 2019;51:835-843.
    PubMed     Abstract available


    April 2019
  43. RODRIGUEZ-LEAL D, Xu C, Kwon CT, Soyars C, et al
    Evolution of buffering in a genetic circuit controlling plant stem cell proliferation.
    Nat Genet. 2019 Apr 15. pii: 10.1038/s41588-019-0389.
    PubMed     Abstract available


    March 2019
  44. RAUCH A, Haakonsson AK, Madsen JGS, Larsen M, et al
    Author Correction: Osteogenesis depends on commissioning of a network of stem cell transcription factors that act as repressors of adipogenesis.
    Nat Genet. 2019 Mar 25. pii: 10.1038/s41588-019-0400.
    PubMed     Abstract available


  45. LIU Q, Liu K, Cui G, Huang X, et al
    Author Correction: Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction.
    Nat Genet. 2019 Mar 7. pii: 10.1038/s41588-019-0388.
    PubMed     Abstract available


  46. RAUCH A, Haakonsson AK, Madsen JGS, Larsen M, et al
    Osteogenesis depends on commissioning of a network of stem cell transcription factors that act as repressors of adipogenesis.
    Nat Genet. 2019 Mar 4. pii: 10.1038/s41588-019-0359.
    PubMed     Abstract available


  47. TAKAHASHI S, Miura H, Shibata T, Nagao K, et al
    Genome-wide stability of the DNA replication program in single mammalian cells.
    Nat Genet. 2019;51:529-540.
    PubMed     Abstract available


    February 2019
  48. LIU Q, Liu K, Cui G, Huang X, et al
    Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction.
    Nat Genet. 2019 Feb 18. pii: 10.1038/s41588-019-0346.
    PubMed     Abstract available


  49. POLLEX T, Heard E
    Nuclear positioning and pairing of X-chromosome inactivation centers are not primary determinants during initiation of random X-inactivation.
    Nat Genet. 2019;51:285-295.
    PubMed     Abstract available


    September 2018
  50. MAS G, Blanco E, Ballare C, Sanso M, et al
    Promoter bivalency favors an open chromatin architecture in embryonic stem cells.
    Nat Genet. 2018 Sep 17. pii: 10.1038/s41588-018-0218.
    PubMed     Abstract available


    February 2018
  51. GUALLAR D, Bi X, Pardavila JA, Huang X, et al
    RNA-dependent chromatin targeting of TET2 for endogenous retrovirus control in pluripotent stem cells.
    Nat Genet. 2018 Feb 26. pii: 10.1038/s41588-018-0060.
    PubMed     Abstract available


    December 2017
  52. VERMA N, Pan H, Dore LC, Shukla A, et al
    Publisher Correction: TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells.
    Nat Genet. 2017 Dec 18. pii: 10.1038/s41588-017-0024.
    PubMed     Abstract available


  53. VERMA N, Pan H, Dore LC, Shukla A, et al
    Author Correction: TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells.
    Nat Genet. 2017 Dec 18. pii: 10.1038/s41588-017-0025.
    PubMed     Abstract available


  54. VERMA N, Pan H, Dore LC, Shukla A, et al
    TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells.
    Nat Genet. 2017 Dec 4. pii: 10.1038/s41588-017-0002.
    PubMed     Abstract available


    September 2017
  55. HUANG PY, Kandyba E, Jabouille A, Sjolund J, et al
    Lgr6 is a stem cell marker in mouse skin squamous cell carcinoma.
    Nat Genet. 2017 Sep 25. doi: 10.1038/ng.3957.
    PubMed     Abstract available


  56. MZOUGHI S, Zhang J, Hequet D, Teo SX, et al
    PRDM15 safeguards naive pluripotency by transcriptionally regulating WNT and MAPK-ERK signaling.
    Nat Genet. 2017;49:1354-1363.
    PubMed     Abstract available


    July 2017
  57. SUN R, Hu Z, Sottoriva A, Graham TA, et al
    Between-region genetic divergence reflects the mode and tempo of tumor evolution.
    Nat Genet. 2017;49:1015-1024.
    PubMed     Abstract available


  58. KHOUEIRY R, Sohni A, Thienpont B, Luo X, et al
    Lineage-specific functions of TET1 in the postimplantation mouse embryo.
    Nat Genet. 2017;49:1061-1072.
    PubMed     Abstract available


    June 2017
  59. DE IACO A, Planet E, Coluccio A, Verp S, et al
    DUX-family transcription factors regulate zygotic genome activation in placental mammals.
    Nat Genet. 2017;49:941-945.
    PubMed     Abstract available


  60. WHIDDON JL, Langford AT, Wong CJ, Zhong JW, et al
    Conservation and innovation in the DUX4-family gene network.
    Nat Genet. 2017;49:935-940.
    PubMed     Abstract available


    May 2017
  61. JENKINSON G, Pujadas E, Goutsias J, Feinberg AP, et al
    Potential energy landscapes identify the information-theoretic nature of the epigenome.
    Nat Genet. 2017;49:719-729.
    PubMed     Abstract available


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