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15.12.2025

9 Biomaterials
2 Blood
1 BMC Cancer
3 Bone
2 Bone Marrow Transplant
3 Cancer
2 Cell
6 Cell Stem Cell
2 Development
1 FEBS Lett
1 J Immunol
1 Leuk Lymphoma
1 Leuk Res
1 PLoS Biol
1 PLoS Genet
5 PLoS One
4 Proc Natl Acad Sci U S A
3 Science
3 Stem Cells


   Retrieve available abstracts of this week’s articles:
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Single Articles


    Biomaterials

  1. KOTLARZ M, O'Keeffe C, S Kronemberger G, Burdis R, et al
    Biofabrication and in vivo evaluation of a hybrid osteochondral implant consisting of structurally organised engineered cartilage on a 3D-printed metal scaffold.
    Biomaterials. 2026;327:123788.
    PubMed         Abstract available

  2. WANG R, Zhou J, Li X, Xiong D, et al
    Chaotropic ion-tuned protein/peptide hydrogel with enhanced trans-barrier delivery for effective periodontitis management via pathogen clearance, immunomodulation, and MSC preservation.
    Biomaterials. 2026;327:123781.
    PubMed         Abstract available

  3. YU X, Zeng L, Chen H, Dong X, et al
    Blood-testis barrier-crossing extracellular vesicles for asthenozoospermia therapy via synergistic ATP replenishment and ferroptosis suppression.
    Biomaterials. 2026;327:123777.
    PubMed         Abstract available

  4. MA L, Zhang Z, Mu Y, Liu B, et al
    Generation of engineered human spinal cord organoid in channel-patterned collagen and transplantation for spinal cord regeneration.
    Biomaterials. 2026;327:123753.
    PubMed         Abstract available

  5. SEMPERTEGUI N, Yan Y, Whitman MA, Beeghly GF, et al
    Mineralized bone matrix attenuates breast cancer cell malignancy by altering MSC mechanoregulation.
    Biomaterials. 2026;327:123763.
    PubMed         Abstract available

  6. PARK H, Yu I, Kim TJ, Jang H, et al
    Human bone marrow niche organoids for disease modeling and therapeutic application in hematopoietic syndrome.
    Biomaterials. 2026;327:123744.
    PubMed         Abstract available

  7. DU J, Huang Y, Liu Y, Wu Y, et al
    Advanced biomaterial-based strategies for craniofacial bone regeneration.
    Biomaterials. 2026;327:123736.
    PubMed         Abstract available

  8. LIU Z, Wong DSL, Parikh BH, Li J, et al
    Development of a biodegradable smooth-surface microcarrier for retinal pigment epithelial cell expansion and maturation.
    Biomaterials. 2026;327:123742.
    PubMed         Abstract available

  9. DWYER KD, Soepriatna AH, Snyder CA, Callanan A, et al
    A coordinated biomaterial strategy for post-infarction cardiac repair: integrating tailored mechanical reinforcement with hiPSC-derived cardiomyocytes in composite engineered human myocardium for remuscularization.
    Biomaterials. 2026;327:123727.
    PubMed         Abstract available


    Blood

  10. DEREVYANKO PK, Swart LE, Mata Casimiro LD, van Oort A, et al
    Fusion Gene Depletion Eliminates Stemness and Induces Bidirectional Differentiation of Acute Myeloid Leukemia.
    Blood. 2025 Sep 24:blood.2025028988. doi: 10.1182/blood.2025028988.
    PubMed         Abstract available

  11. MEYER E, Salhotra A, Gandhi A, Pantin J, et al
    Orca-T versus allogeneic hematopoietic stem cell transplantation (PRECISION-T): a multicenter, randomized phase 3 trial.
    Blood. 2025 Dec 12:blood.2025031313. doi: 10.1182/blood.2025031313.
    PubMed         Abstract available


    BMC Cancer

  12. BUSHAWAY S, Naumann K, Singh B, Maher C, et al
    Preparing for allogeneic hematopoietic stem cell transplant: a multidisciplinary prehabilitation intervention is safe, feasible and demonstrates preliminary efficacy in acute myeloid leukemia and myelodysplastic syndromes.
    BMC Cancer. 2025 Dec 9. doi: 10.1186/s12885-025-15417.
    PubMed        


    Bone

  13. FU Y, Meng L, Zhang M, Li L, et al
    ED-71 alleviates OVX-induced osteoporosis by inhibiting macrophage senescence through SIRT1/PGC-1alpha pathway: A potential therapeutic approach.
    Bone. 2026;203:117737.
    PubMed         Abstract available

  14. OLSEN A, Premnath P, Brunet S, Larijani L, et al
    Enhanced fracture repair in p21(-/-) mice is mediated through increased callus mineralization.
    Bone. 2026;203:117732.
    PubMed         Abstract available

  15. MIZUKI N, Mukai M, Shiga Y, Takayama N, et al
    Bone morphogenetic protein-2-independent bone formation by human iPSC-derived megakaryocytes and platelets.
    Bone. 2026;203:117703.
    PubMed         Abstract available


    Bone Marrow Transplant

  16. PASVOLSKY O, Marcoux C, Milton DR, Haider AA, et al
    Results of delayed or salvage autologous hematopoietic stem cell transplantation for multiple myeloma.
    Bone Marrow Transplant. 2025 Dec 5. doi: 10.1038/s41409-025-02771.
    PubMed         Abstract available

  17. SHEIKH IN, Alqahtani S, Okeleji O, Brown BD, et al
    Pre-transplant immunosuppression in pediatric patients undergoing haploidentical stem cell transplant for sickle cell disease is associated with positive outcomes.
    Bone Marrow Transplant. 2025 Dec 10. doi: 10.1038/s41409-025-02776.
    PubMed        


    Cancer

  18. SICURANZA A, Pacelli P, Santoni A, Raspadori D, et al
    Reply to "Peripheral blood CD26+ leukemic stem cells in chronic myeloid leukemia and tyrosine kinase inhibitor response: Questions remain!".
    Cancer. 2025;131:e70214.
    PubMed        

  19. OZDEMIR ZN, Eskazan AE
    Peripheral blood CD26+ leukemic stem cells in chronic myeloid leukemia and tyrosine kinase inhibitor response: Questions remain!
    Cancer. 2025;131:e70215.
    PubMed        

  20. WANNAPHUT C, Chumnumsiriwath P, Ciurea SO, Kongtim P, et al
    Outcomes of fludarabine-melphalan versus fludarabine-busulfan reduced-intensity conditioning regimens for allogeneic hematopoietic stem cell transplantation in patients with hematologic malignancies: A systematic review and meta-analysis.
    Cancer. 2025;131:e70199.
    PubMed         Abstract available


    Cell

  21. HE S, Luo CL, Luo T, Chen HT, et al
    Systemic immune activity occurs during human immune system maturation.
    Cell. 2025;188:7291-7308.
    PubMed         Abstract available

  22. CHANG JW, Na HK, Chang KW, Park CW, et al
    Phase 1/2a clinical trial of hESC-derived dopamine progenitors in Parkinson's disease.
    Cell. 2025;188:7036-7048.
    PubMed         Abstract available


    Cell Stem Cell

  23. LAI SB, Hung YJ, Marin-Juez R
    When the heart calls for help: Clusterin reprograms immunity to enable regeneration.
    Cell Stem Cell. 2025;32:1793-1795.
    PubMed         Abstract available

  24. PANG W, Xiang Y
    Unlocking human brain networks by assembling circuits in vitro and in vivo.
    Cell Stem Cell. 2025;32:1795-1797.
    PubMed         Abstract available

  25. TAN T, Lu X, Li T, Wei J, et al
    An exploratory proposal for a revision to the 14-day rule in the regulatory context of China.
    Cell Stem Cell. 2025;32:1798-1801.
    PubMed         Abstract available

  26. HAO Y, Chen Q, Yin J, Ding L, et al
    Optimizing translational efficiency in stem cell clinical research.
    Cell Stem Cell. 2025;32:1802-1806.
    PubMed         Abstract available

  27. RAO Y, Bai Y, Li X, Du B, et al
    The evolution of microglia replacement: A new paradigm for CNS disease therapy.
    Cell Stem Cell. 2025;32:1807-1832.
    PubMed         Abstract available

  28. LIU Y, Zhu J, Lu X, Zhuang X, et al
    Human PSC-derived organoids model sympathetic ganglion development and its functional crosstalk with the heart.
    Cell Stem Cell. 2025 Dec 11:S1934-5909(25)00410.
    PubMed         Abstract available


    Development

  29. CETIN R, Picco G, van Staalduinen J, Bindels E, et al
    Distinct roles of Atf3, Zfp711 and Bcl6b in early embryonic hematopoietic and endothelial lineage specification.
    Development. 2025;152:dev204792.
    PubMed         Abstract available

  30. HOFE P, Harrington A, Gardner T, DiNardo S, et al
    Tbx1 ortholog org-1 is required to establish testis stem cell niche identity in Drosophila.
    Development. 2025 Dec 11:dev.204914. doi: 10.1242/dev.204914.
    PubMed         Abstract available


    FEBS Lett

  31. CEREZO EL, Anderson J, Vedrenne ED, Martin NY, et al
    Hematopoietic (stem) cells-The elixir of life?
    FEBS Lett. 2025 Dec 4. doi: 10.1002/1873-3468.70215.
    PubMed         Abstract available


    J Immunol

  32. FUJIKI T, Nishimura R, Sato K, Kuroda R, et al
    Recombinant human soluble thrombomodulin prevents murine sclerodermatous chronic graft-versus-host disease.
    J Immunol. 2025 Dec 13:vkaf169. doi: 10.1093.
    PubMed         Abstract available


    Leuk Lymphoma

  33. CABELLO MODESTO D, McCulloch S, Tay J, Jimenez Zepeda VH, et al
    Autologous stem cell transplantation for the treatment of MGRS (monoclonal gammopathy of renal significance): experience from the University of Calgary.
    Leuk Lymphoma. 2025 Dec 9:1-3. doi: 10.1080/10428194.2025.2598362.
    PubMed        


    Leuk Res

  34. BHATIA I, Patel S, Pearson L, Parthiban K, et al
    Outcomes of adults older than 70 years of age undergoing allogeneic stem cell transplantation.
    Leuk Res. 2025;160:108145.
    PubMed         Abstract available


    PLoS Biol

  35. WU QC, Swaminathan A, Winward A, Lalonde L, et al
    IL-17 stimulates erythropoiesis in vivo by amplifying the response of erythroid progenitors to erythropoietin.
    PLoS Biol. 2025;23:e3003462.
    PubMed         Abstract available


    PLoS Genet

  36. AZLAN A, Fukunaga R
    MYCBP interacts with Sakura and Otu and is essential for germline stem cell renewal and differentiation and oogenesis.
    PLoS Genet. 2025;21:e1011792.
    PubMed         Abstract available


    PLoS One

  37. LI Y, Liu B, Hu G, Zhou T, et al
    Human umbilical cord-derived mesenchymal stem cells alleviate autoimmune hepatitis by inhibiting hepatic ferroptosis.
    PLoS One. 2025;20:e0337060.
    PubMed         Abstract available

  38. SUN X, Huang B, Ruan G, Xu A, et al
    Exosomes from bone marrow mesenchymal stem cells protect melanocytes under vitiligo-related conditions through induction of NRF2/HO1 expression.
    PLoS One. 2025;20:e0338323.
    PubMed         Abstract available

  39. WENG Q, Osaka T, Onoe H, Yoshida K, et al
    Use of a new micropattern tape method to detect chirality shifts in differentiating C2C12 cells.
    PLoS One. 2025;20:e0338032.
    PubMed         Abstract available

  40. STRIEDINGER K, Barruet E, Atamaniauc E, Linquist K, et al
    Control of quiescence and activation of human muscle stem cells by cytokines.
    PLoS One. 2025;20:e0327701.
    PubMed         Abstract available

  41. WILLIAMS LM, Fujimoto T, Damodarasamy M, Weaver RR, et al
    Transport of CCL2 across an induced pluripotent stem cell-derived in vitro model of the human blood-brain barrier is heparan sulfate-dependent.
    PLoS One. 2025;20:e0338780.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  42. GAO J, Yang F, Jiang Y, Zheng Y, et al
    TAPT1 interacts with SUCO to maintain the homeostasis of newly synthesized proteins and brain development in mice.
    Proc Natl Acad Sci U S A. 2025;122:e2501361122.
    PubMed         Abstract available

  43. WANG Y, Liu F, Shan Q, Wang X, et al
    Functional recovery induced by KCC2-enabled relay pathways in completely injured spinal cords in adult rats.
    Proc Natl Acad Sci U S A. 2025;122:e2421823122.
    PubMed         Abstract available

  44. ROURA-MARTINEZ D, Popa N, Jaouen F, Rombaut C, et al
    Combination of Cas9 and adeno-associated vectors enables efficient in vivo knockdown of precise miRNAs in the rodent and primate brain.
    Proc Natl Acad Sci U S A. 2025;122:e2513076122.
    PubMed         Abstract available

  45. XIA J, Shen L, Liu Y, Wang L, et al
    Ace2 safeguards embryonic hematopoietic stem and progenitor cell production by restraining Nlrp3-mediated pyroptosis.
    Proc Natl Acad Sci U S A. 2025;122:e2515641122.
    PubMed         Abstract available


    Science

  46. ZHU X, Chen X, Liu Y, Zhu Y, et al
    Cell wall patterning regulates plant stem cell dynamics.
    Science. 2025;390:1064-1070.
    PubMed         Abstract available

  47. MARIN-GONZALEZ A, Rybczynski AT, Nilavar NM, Nguyen D, et al
    Cohesin drives chromatin scanning during the RAD51-mediated homology search.
    Science. 2025;390:eadw1928.
    PubMed         Abstract available

  48. PETRIS G, Grazioli S, van Bijsterveldt L, Murat P, et al
    High-fidelity human chromosome transfer and elimination.
    Science. 2025;390:1038-1043.
    PubMed         Abstract available


    Stem Cells

  49. FATEH K, Atashi A
    Critical Insights into Umbilical Cord Blood and Tissue Stem Cells: Navigating Challenges to Enhance Clinical Translation - A Narrative Review.
    Stem Cells. 2025 Dec 8:sxaf077. doi: 10.1093.
    PubMed         Abstract available

  50. LIU H, Nie R, Jiang J, Zhang C, et al
    Stem cell therapy for osteoradionecrosis of the jaws: Mechanisms, advances, and clinical potential.
    Stem Cells. 2025 Dec 13:sxaf078. doi: 10.1093.
    PubMed         Abstract available

  51. KASSIS AR, Ganapathy A, Mechaal A, An S, et al
    Valproic acid-expanded cord blood CD34+CD90+ cells are functionally distinct based on their origin.
    Stem Cells. 2025 Dec 13:sxaf079. doi: 10.1093.
    PubMed         Abstract available


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