: The AMEDEO Literature Guide

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Stroke

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Articles published in BMJ Open
Retrieve available abstracts of 398 articles:
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Single Articles

April 2025

HARCOURT B, Brown R, Bowen A
Informal caregiving following stroke: a qualitative exploration of carer self-identification, care-related language and support experiences.
BMJ Open. 2025;15:e089582.
PubMed Abstract available

NEZON E, Patel T, Benson K, Chan K, et al
Combining functional electrical stimulation with visual feedback balance training: a qualitative study of end-user perspectives on designing a clinically feasible intervention.
BMJ Open. 2025;15:e090791.
PubMed Abstract available

MOELGG K, Karisik A, Dejakum B, Felicetti S, et al
Longitudinal dynamics of pulse wave velocity in the days after acute ischaemic stroke: prospective cohort study.
BMJ Open. 2025;15:e089304.
PubMed Abstract available

HUYNH J, Chabala C, Sharma S, Choo L, et al
Effectiveness and safety of shortened intensive treatment for children with tuberculous meningitis (SURE): a protocol for a phase 3 randomised controlled trial evaluating 6 months of antituberculosis therapy and 8 weeks of aspirin in Asian and African
BMJ Open. 2025;15:e088543.
PubMed Abstract available

March 2025

NGUYEN CP, Uyttenboogaart M, Maas WJ, Buskens E, et al
Drive-the-doctor paradigm in acute ischaemic stroke for improving regional stroke care networks: a cost-effectiveness analysis.
BMJ Open. 2025;15:e091413.
PubMed Abstract available

BAIG SS, Mooney C, McKendrick K, Duffy KEM, et al
TRanscutaneous lImb reCovEry Post-Stroke (TRICEPS): study protocol for a randomised, controlled, multiarm, multistage adaptive design trial.
BMJ Open. 2025;15:e092520.
PubMed Abstract available

DAVIES A, Chapman S, Mullin S, Bakhbakhi D, et al
Qualitative study exploring the barriers and facilitators to low-dose aspirin adherence in pregnant women with placental dysfunction risk in the UK.
BMJ Open. 2025;15:e093888.
PubMed Abstract available

PAN X, Du W, Liu Z
Poor clinical outcome despite successful recanalisation in patients with acute myocardial infarction undergoing direct percutaneous coronary intervention: a retrospective cohort study.
BMJ Open. 2025;15:e097434.
PubMed Abstract available

ZHANG R, Hong J, Zheng X, Chen S, et al
Effects of poststroke heart rate variability on the neurological impairment severity and the prognosis among patients with ischaemic stroke: a scoping review.
BMJ Open. 2025;15:e092826.
PubMed Abstract available

Correction: Intra-arterial alteplase for acute ischaemic stroke after mechanical thrombectomy (PEARL): rationale and design of a multicentre, prospective, open-label, blinded-endpoint, randomised controlled trial.
BMJ Open. 2025;15:e091059corr2.
PubMed

SPIEGELENBERG JP, Verburgt E, den Hertog H, de Laat KF, et al
Role of inflammation and haemostasis on aetiology and prognosis in young patients with ischaemic stroke: study protocol of the Observational Dutch Young Symptomatic StrokE study-EXTended (ODYSSEY-nEXT) - a multicentre prospective cohort study.
BMJ Open. 2025;15:e096330.
PubMed Abstract available

TRAN KH, Akhtar N, Ali A, Joseph S, et al
Impact of stroke severity on aspiration pneumonia risks in the medical ward versus the stroke unit: a 10-year retrospective cohort study.
BMJ Open. 2025;15:e093328.
PubMed Abstract available

DEJONG C, Durstenfeld MS, Davis JD, Wang CS, et al
Delivering guideline-directed medical therapy for heart failure with reduced ejection fraction as an over-encapsulated polypill: rationale and protocol for the COMBO-HF-X pilot crossover randomised clinical trial.
BMJ Open. 2025;15:e093663.
PubMed Abstract available

LIUZHUANG X, Yang S, Yang Y, Gu W, et al
Relationship between the HDL-C/CRP ratio and all-cause mortality in patients with chronic heart failure: a retrospective analysis from Yunnan Province, China.
BMJ Open. 2025;15:e084099.
PubMed Abstract available

ZHANG T, Zhou J, Zhang K, Zhang C, et al
Different antithrombotic strategies after left atrial appendage closure with the LACbes occluder: protocol of the DAAL trial.
BMJ Open. 2025;15:e084351.
PubMed Abstract available

LI W, Yao B, Wu J, Xu Y, et al
Mechanistic study of transcranial magnetic stimulation intervention for poststroke attention deficit: a randomised controlled trial protocol.
BMJ Open. 2025;15:e088980.
PubMed Abstract available

WIYARTA E, Hidayat R, Kurniawan M, Sinaga GHP, et al
Factors associated with prehospital and in-hospital delays in acute ischaemic stroke care in Indonesia: a systematic review.
BMJ Open. 2025;15:e095845.
PubMed Abstract available

XU CY, Zou P, Chen X, Li SL, et al
What are the symptom trajectories of self-regulatory fatigue among family caregivers of stroke survivors? A protocol of mixed-methods study in Chinese rehabilitation settings.
BMJ Open. 2025;15:e092724.
PubMed Abstract available

BURNS P, Eddy RL, Li X, Yang J, et al
The Canadian Lung Outcomes in Users of Vaping Devices (CLOUD) Study: protocol for a prospective, observational cohort study.
BMJ Open. 2025;15:e100568.
PubMed Abstract available

MENG D, Zhou X, Gao Y, Lu Y, et al
Clinical factors influencing intravenous thrombolysis in patients with cerebral infarction: a retrospective cohort study comparing private car and ambulance transport in Jiaxing, China.
BMJ Open. 2025;15:e087326.
PubMed Abstract available

JEFFRIES M, Abuzour ASM, Ashcroft D, Avery T, et al
Understanding the implementation of a multidisciplinary intervention using a suite of prescribing safety indicators to improve medication safety in prison healthcare settings: a qualitative study.
BMJ Open. 2025;15:e086309.
PubMed Abstract available

ZHAO ZJ, Wang H, Ye Q, Zhang ZF, et al
Effect of electroacupuncture on the incidence of acute stroke after embolisation of intracranial aneurysm: study protocol for a single-centre, double-blinded, randomised controlled trial.
BMJ Open. 2025;15:e090502.
PubMed Abstract available

MOREIRA-SOTO A, Beuchel C, Tabares X, Wulf B, et al
Socioeconomic determinants potentially underlying differential global SARS-CoV-2 testing capacity: an ecological study.
BMJ Open. 2025;15:e090804.
PubMed Abstract available

WANG X, Chen X, Chan KLC, Li X, et al
Does the alternating timing of rTMS combined with soft-hand rehabilitation robot affect the recovery of hand function in patients after stroke? A study protocol for a multicentre randomised controlled trial.
BMJ Open. 2025;15:e094672.
PubMed Abstract available

February 2025

SAMMONS E, Bowman L, Stevens W, Buck G, et al
Effects of aspirin and omega-3 fatty acids on age-related macular degeneration in ASCEND-Eye: a randomised placebo-controlled trial in a population with diabetes.
BMJ Open. 2025;15:e090605.
PubMed Abstract available

HAWKE LD, Husain MI, Amartey A, Ma C, et al
Narrative enhancement and cognitive therapy for self-stigma among youth with bipolar disorder or multiple mental health conditions: protocol for a pilot randomised basket trial.
BMJ Open. 2025;15:e096222.
PubMed Abstract available

MILES K, Barnes S, Kim JH, Ohalloran R, et al
Listening-in-noise difficulties following stroke: a scoping review protocol.
BMJ Open. 2025;15:e093399.
PubMed Abstract available

YANG N, Sun Z, Liu J, Hao Y, et al
Impact of insurance coverage for non-vitamin K antagonist oral anticoagulants on quality of care and care disparities in patients hospitalised with atrial fibrillation in tertiary hospitals in China: interrupted time series analysis.
BMJ Open. 2025;15:e088539.
PubMed Abstract available

WEGERIF EC, Mol BM, Unlu C, de Borst GJ, et al
Medication adherence of patients with peripheral arterial disease to antithrombotic therapy: a systematic review.
BMJ Open. 2025;15:e085056.
PubMed Abstract available

KLUIT L, Hoving JL, Jamaludin FS, van Bennekom CAM, et al
Effectiveness of clinical healthcare interventions for enhancing the work participation of patients with various health conditions: a synthesis of systematic reviews.
BMJ Open. 2025;15:e094201.
PubMed Abstract available

GAROT P, Nielsen-Kudsk JE, Freixa X, Berti S, et al
Contemporary European practice in left atrial appendage closure: results from a survey focusing on planning, techniques and post-implantation management.
BMJ Open. 2025;15:e090541.
PubMed Abstract available

KORNELIUS E, Lo SC, Huang CN, Wang CC, et al
Association of herpes zoster vaccination and cardiovascular risk in patients with diabetes: long-term insights from a retrospective cohort study.
BMJ Open. 2025;15:e090428.
PubMed Abstract available

TEDESCO TRICCAS L, Sporn S, Coll I Omana M, Brander F, et al
High-dose high-intensity Queen Square upper-limb rehabilitation for people with chronic stroke (INTENSIVE): protocol for a single-centre, randomised controlled trial.
BMJ Open. 2025;15:e095766.
PubMed Abstract available

BALAGNY P, D'Ortho MP, Berard L, Rousseau A, et al
AMI-Sleep: protocol for a prospective study of sleep-disordered breathing/sleep apnoea syndrome and incident cardiovascular events after acute myocardial infarction.
BMJ Open. 2025;15:e090093.
PubMed Abstract available

KJOLHEDE EA, Carlsen HK, Martyn O, Svensson L, et al
Hospitalisation from seasonal influenza among persons with type 1 diabetes: a cohort study from the Swedish National Diabetes Register.
BMJ Open. 2025;15:e084165.
PubMed Abstract available

MORRIS JH, Irvine LA, Breckenridge J, Farre A, et al
Keeping Active with Texting after Stroke (KATS): a single-arm feasibility and acceptability study of a behavioural intervention to promote community-based physical activity after stroke rehabilitation.
BMJ Open. 2025;15:e093838.
PubMed Abstract available

LABORANTE R, Delvinioti A, Tudor AM, Lenkowicz J, et al
Temporal trends in guideline-recommended medical therapy after an acute heart failure decompensation event: an observational analysis from Generator Heart Failure DataMart.
BMJ Open. 2025;15:e088998.
PubMed Abstract available

NORTOFT M, Sorensen D, Aadal L
Nutritional interventions to prevent and reduce overweight and obesity during postacute stroke rehabilitation: a scoping review protocol.
BMJ Open. 2025;15:e092156.
PubMed Abstract available

ZIAI W, Woo D, Sansing L, Hanley D, et al
The REpeated ASSEssment of SurvivorS in intracerebral haemorrhage: protocol for a multicentre, prospective observational study.
BMJ Open. 2025;15:e094322.
PubMed Abstract available

SEXTON E, O'Flaherty M, Hickey A, Williams DJ, et al
Forecasting stroke and stroke-driven dementia in a rapidly ageing population: a model-based analysis of alternative projection scenarios for Ireland.
BMJ Open. 2025;15:e091557.
PubMed Abstract available

SORENSEN VFI, Eddelien HS, Butt JH, Kruuse C, et al
Patient-reported symptoms and admission pathways in stroke mimics versus confirmed stroke or transient ischaemic attack: a cross-sectional observational study.
BMJ Open. 2025;15:e088014.
PubMed Abstract available

HAMILTON E, Shone L, Reynolds C, Wu J, et al
Perceptions of healthcare professionals on the use of a risk prediction model to inform atrial fibrillation screening: qualitative interview study in English primary care.
BMJ Open. 2025;15:e091675.
PubMed Abstract available

CHEN Y, Xia N, Li J, Liang W, et al
Effect of intermittent theta burst stimulation combined with acoustic startle priming motor training on upper limb motor function and neural plasticity in stroke individuals: study protocol for a randomised controlled proof-of-concept trial.
BMJ Open. 2025;15:e090049.
PubMed Abstract available

January 2025

FITZHUGH C, Jones H, Foweather L, Lip GYH, et al
Exercise-based cardiac rehabilitation for patients with atrial fibrillation receiving catheter ablation: protocol for a feasibility randomised controlled trial (RCT) with embedded process evaluation.
BMJ Open. 2025;15:e088460.
PubMed Abstract available

BUTCHER T, Warland A, Stewart V, Aweid B, et al
Rehabilitation using virtual gaming for Hospital and hOMe-Based training for the Upper limb in acute and subacute Stroke (RHOMBUS II): results of a feasibility randomised controlled trial.
BMJ Open. 2025;15:e089672.
PubMed Abstract available

HE W, Cai Y, Hao C, Chen Z, et al
Effectiveness of using implementation frameworks to facilitate the implementation of a stroke management guideline in the traditional Chinese medicine hospitals in China: protocol for a factorial randomised controlled trial.
BMJ Open. 2025;15:e078103.
PubMed Abstract available

VAKIL P, Ferre P, Higgins J, Beaulieu LD, et al
Descriptive retrospective cross-sectional study of rehabilitation care for poststroke users in Quebec during the COVID-19 pandemic.
BMJ Open. 2025;15:e082602.
PubMed Abstract available

MIAZGA E, Reed C, Olsthoorn A, Fan I, et al
Investigating the implementation of a Trial of Labour After Caesarean (TOLAC) delivery bundle with respect to decreasing caesarean delivery rates: a multisite quality improvement initiative.
BMJ Open. 2025;15:e088734.
PubMed Abstract available

BILAK JM, Squire I, Wormleighton JV, Brown RL, et al
The Protocol for the Multi-Ethnic, multi-centre raNdomised controlled trial of a low-energy Diet for improving functional status in heart failure with Preserved ejection fraction (AMEND Preserved).
BMJ Open. 2025;15:e094722.
PubMed Abstract available

MACARTHUR C, Bick D, Salmon V, Jones E, et al
Antenatal pelvic floor muscle exercise intervention led by midwives in England to reduce postnatal urinary incontinence: APPEAL feasibility and pilot randomised controlled cluster trial.
BMJ Open. 2025;15:e091248.
PubMed Abstract available

ZOROWITZ RD, Barrenechea LS, Butet S, Groppa S, et al
How many stroke survivors develop problematic spasticity requiring pharmacological therapy? An international (Europe and USA) observational study protocol.
BMJ Open. 2025;15:e087404.
PubMed Abstract available

LI C, Wu Z, Jiang Y, Zhao Q, et al
Healthcare-seeking delays and associated factors among immigrant patients with acute ischaemic stroke in Shenzhen: a retrospective observational study.
BMJ Open. 2025;15:e087156.
PubMed Abstract available

LIU J, Huang Z, Luo F, Guo Y, et al
Effect of metformin on the clinical outcomes of stroke in patients with diabetes: a systematic review and meta-analysis.
BMJ Open. 2025;15:e092214.
PubMed Abstract available

HOBDEN G, Tabone F, Demeyere N
Research investigating patient and carer psychoeducation needs regarding post-stroke cognition: a scoping review.
BMJ Open. 2025;15:e084681.
PubMed Abstract available

KLIEVERIK VM, Kanning JP, Rissanen IL, Rannikmae K, et al
Development and external validation of the SMA(2)SH(2)ERS risk prediction model for aneurysmal subarachnoid haemorrhage in the general population: a population-based prospective cohort study.
BMJ Open. 2025;15:e091756.
PubMed Abstract available

DAVARI M, Fatemi B, Sadeghipour P, Kebriaeezadeh A, et al
Cost-utility analysis of combination medical therapies in chronic coronary syndrome: a comparative study using real-world and patient-level data from Iran.
BMJ Open. 2025;15:e081953.
PubMed Abstract available

MATUSEVICIUS M, Paiva Nunes A, Krishnan M, Egido J, et al
Safe Implementation of Treatments in Stroke: a study on intravenous thrombolysis in patients over 80 years of age with acute ischaemic stroke.
BMJ Open. 2025;15:e087454.
PubMed Abstract available

CIMEN E, Ng K, Buck BH, Field T, et al
Importance of infarct topography in determination of stroke mechanism and recurrence risk: a post-hoc analysis of the dabigatran acute treatment of stroke trial.
BMJ Open. 2025;15:e087704.
PubMed Abstract available

HADNORNTUN P, Prawjaeng J, Kongmalai T, Tanvijit P, et al
Botulinum toxin type A for the treatment of patients with post-stroke spasticity in Thailand: cost-utility and budget impact analysis.
BMJ Open. 2025;15:e090701.
PubMed Abstract available

HU Z, Zhang K, Wu Y, Wang X, et al
Oxygenation targets for endovascular therapy in acute ischemic stroke patients (Oxy-TARGET): protocol for a single-centre, open-label randomised controlled trial.
BMJ Open. 2025;15:e086234.
PubMed Abstract available

LIAO LY, Wang PY, Zhu Y, Peng QY, et al
Effects of transcranial magnetic stimulation combined with extracorporeal shockwave therapy for poststroke spasticity: study protocol for a randomised controlled trial.
BMJ Open. 2025;15:e086300.
PubMed Abstract available

December 2024

WANG Y, Hu X, Cheng L, Guo X, et al
Pre-diabetes virtual health management community (VHMC) intervention and group interaction management model in China: a randomised clinical trial protocol.
BMJ Open. 2024;14:e086268.
PubMed Abstract available

BROOMFIELD N, Walters M, West RM
Carer strain in post-stroke emotionalism: a cross-sectional analysis.
BMJ Open. 2024;14:e084079.
PubMed Abstract available

YANG Y, Xu H, Chang W, Li C, et al
Effectiveness and compliance of telemedicine on blood pressure management in poststroke patients: a systematic review and meta-analysis of randomised controlled trials.
BMJ Open. 2024;14:e083461.
PubMed Abstract available

KEETLEY R, Manning JC, Kettlewell J, Williams J, et al
Enabling participation in community-dwelling children and young people with acquired brain injuries and their families: a theory-based, evidence-based and person-based approach to intervention development.
BMJ Open. 2024;14:e088516.
PubMed Abstract available

LANNIN NA, Crotty M, Cameron ID, Chen Z, et al
Cost efficiency of inpatient rehabilitation following acquired brain injury: the first international adaptation of the UK approach.
BMJ Open. 2024;14:e094892.
PubMed Abstract available

ZHAO Z, Wang X, Zhang C, Wang S, et al
Self-advocacy positive perceptions and stage experiences in patients who had a stroke: a qualitative study in China.
BMJ Open. 2024;14:e091273.
PubMed Abstract available

ZHANG X, Zhao J, Sun Z, Wei D, et al
Effects of minocycline on patients with acute anterior circulation ischaemic stroke undergoing intravenous thrombectomy (MIST-A): the study protocol for a multicentre, prospective, randomised, open-label, blinded-endpoint trial.
BMJ Open. 2024;14:e093443.
PubMed Abstract available

AUSTIN R, Khair E, Blakeman T, Hossain MZ, et al
Diagnosing and managing patients with heart failure with preserved ejection fraction: a consensus survey.
BMJ Open. 2024;14:e092993.
PubMed Abstract available

WEI T, Zhou H, Wu S, He F, et al
Efficacy and safety of rivaroxaban in preventing venous thromboembolism in postoperative patients with gynecological malignancies: protocol for a randomised controlled open-label trial (G-alfalfa trial).
BMJ Open. 2024;14:e092164.
PubMed Abstract available

BRADLEY CP, Orchard V, Sykes RA, McKinley G, et al
Heart-brain microvascular MRI study: protocol for a multicentre, observational, cohort study in the UK assessing associations between small vessel disease of the heart and brain.
BMJ Open. 2024;14:e088372.
PubMed Abstract available

KONGMALAI T, Tansawet A, Pattanaprateep O, Ratanatharathorn C, et al
Can SGLT-2 inhibitors improve cardiovascular outcomes and ensure safety for patients with type 2 diabetes and heart failure in Thailand? A real-world multicentre retrospective cohort study.
BMJ Open. 2024;14:e090226.
PubMed Abstract available

KIM YM, Seong J, Kim JH, Nam G, et al
Efficacy of combining aspirin with hydroxychloroquine in pregnancies at high risk for pre-eclampsia: a prospective, multicentre, open-label, single-arm clinical trial, investigator-initiated study (HUGS study).
BMJ Open. 2024;14:e081610.
PubMed Abstract available

NGUYEN CV, Luong CQ, Dao CX, Nguyen MH, et al
Predictive validity of interleukin 6 (IL-6) for the mortality in critically ill COVID-19 patients with the B.1.617.2 (Delta) variant in Vietnam: a single-centre, cross-sectional study.
BMJ Open. 2024;14:e085971.
PubMed Abstract available

GONG H, Luo J, Xu W, Wang J, et al
Drug-eluting stents versus bare-metal stents for intracranial atherosclerotic stenosis: a systematic review and meta-analysis.
BMJ Open. 2024;14:e085533.
PubMed Abstract available

MAY S, Muhlensiepen F, Plotho L, Darkow R, et al
'But I have a cat, I have to talk to her now': a qualitative study on reasons for not participating in guideline-based aphasia therapy from the perspective of patients in German-speaking countries.
BMJ Open. 2024;14:e085849.
PubMed Abstract available

November 2024

VAMSHIKRISHNAPATEL K, Biswas R, Kumar V, Ojha VS, et al
Can high-sensitivity C reactive protein (hsCRP) be used as a prognostic marker of functional disability after acute ischaemic stroke? A cross-sectional study at a tertiary care centre in Eastern India.
BMJ Open. 2024;14:e085078.
PubMed Abstract available

SIKUKA HM, Lupenga J, Nkhata L
Predictors of upper limb motor recovery in stroke survivors: a pre-post test study design.
BMJ Open. 2024;14:e081936.
PubMed Abstract available

STIRNEMANN J, Serratrice J, Mann T, Louge P, et al
Protocol for a multicentric, double-blind, randomised controlled trial of hyperbaric oxygen therapy (HBOT) versus sham for treating vaso-occlusive crisis (VOC) in sickle cell disease (SCD) in patients aged 8 years or older (HBOT-SCD study).
BMJ Open. 2024;14:e084825.
PubMed Abstract available

CRISTALL N, Drozdowska BA, Fladt J, Jaroenngarmsamer T, et al
Priorities and expectations of researchers, funders, patients and the public regarding the funding of medical research: results from the PERSPECT qualitative study.
BMJ Open. 2024;14:e084655.
PubMed Abstract available

ZHU Z, He Y, Zhao J, Liu W, et al
Evaluation of safety and efficacy of intracranial self-expanding drug-eluting stents for symptomatic intracranial atherosclerotic stenosis: a prospective, multicentre, randomised controlled, superiority clinical trial protocol.
BMJ Open. 2024;14:e091152.
PubMed Abstract available

MATSUOKA N, Nakazawa D, Nishio S, Cho KY, et al
Effects of canagliflozin on brain natriuretic peptide levels in patients with type 2 diabetes on peritoneal dialysis in Japan: protocol for a multicentre, prospective, randomised controlled trial (CARD-PD trial).
BMJ Open. 2024;14:e084846.
PubMed Abstract available

TULI W, Teshome E, Jiru T
Knowledge of stroke risk factors and prevention among hypertensive patients on follow-up at Addis Ababa University Tertiary Hospital, Addis Ababa, Ethiopia: a cross-sectional study.
BMJ Open. 2024;14:e089159.
PubMed Abstract available

BRUUN CF, Zarp J, Lyng Forman J, Coello K, et al
Effects of low-dose aspirin in bipolar disorder: study protocol for a randomised controlled trial (the A-Bipolar RCT).
BMJ Open. 2024;14:e084105.
PubMed Abstract available

LATIF A, Al Janabi HF, Joshi M, Fusari G, et al
Use of commercially available wearable devices for physical rehabilitation in healthcare: a systematic review.
BMJ Open. 2024;14:e084086.
PubMed Abstract available

YANG X, He X, Pan D, Xu Y, et al
Intra-arterial alteplase for acute ischaemic stroke after mechanical thrombectomy (PEARL): rationale and design of a multicentre, prospective, open-label, blinded-endpoint, randomised controlled trial.
BMJ Open. 2024;14:e091059.
PubMed Abstract available

XU X, Han Q, Yan Z, Ni J, et al
Effects of phrenic nerve magnetic stimulation on respiratory function in stroke patients: study protocol for a randomised controlled trial.
BMJ Open. 2024;14:e087574.
PubMed Abstract available

October 2024

MOOGHALI M, Zhou T, Ross JS
Direct oral anticoagulant approvals by four major regulatory agencies: a cross-sectional analysis of premarket and postmarket evidence.
BMJ Open. 2024;14:e090376.
PubMed Abstract available

MANSOURI A, Nassiri F, Scales D, Pirouzmand F, et al
Anticoagulation Therapy Timing in patients with Atrial Fibrillation after Acute and Chronic Subdural Haematoma (ATTAACH): a pilot randomised controlled trial.
BMJ Open. 2024;14:e090224.
PubMed Abstract available

DEL GIORNO R, Mazzolai L, Keller S, Siniscalchi C, et al
Assessment of bleeding events in patients receiving DOACs with or without statins to treat venous thromboembolism: insights from the RIETE registry.
BMJ Open. 2024;14:e085401.
PubMed Abstract available

ZENG Y, Liang S, Wang H, Zeng J, et al
Treatments, medical expenses and complications of hospital outpatient healthcare associated with stroke in patients with diabetes in China: a retrospective analysis of the Beijing Municipal Medical Insurance Database.
BMJ Open. 2024;14:e085222.
PubMed Abstract available

SJOLANDER M, Gustafsson M, Holmberg H, Glader EL, et al
Longitudinal changes in self-reported medication adherence and beliefs about post-stroke medicines in Sweden: a repeated cross-sectional study.
BMJ Open. 2024;14:e084680.
PubMed Abstract available

HIVES L, Bray EP, Nowland R, Thomson G, et al
Social media influencers in the space of pregnancy and parenting: a scoping review protocol.
BMJ Open. 2024;14:e087200.
PubMed Abstract available

WU Y, Liu J, Md M, Zhao J, et al
Effectiveness of lower limb robotic rehabilitation on peak of oxygen uptake among patients with stroke: a systematic review and meta-analysis.
BMJ Open. 2024;14:e082985.
PubMed Abstract available

GRIFFITHS J, Adshead F, Al-Shahi Salman R, Anderson C, et al
What is the carbon footprint of academic clinical trials? A study of hotspots in 10 trials.
BMJ Open. 2024;14:e088600.
PubMed Abstract available

PEDLOW K, Kennedy NC, Klempel N, Eng JJ, et al
Post-rehabilitation programme to support upper limb recovery in community-dwelling stroke survivors: a mixed methods cluster-feasibility controlled trial.
BMJ Open. 2024;14:e088301.
PubMed Abstract available

LI Z, Li X, Fu X, Zhou T, et al
Modified tai chi movement training based on sEMG and movement analysis on improving upper extremities motor function: a protocol for a clinical randomised controlled trial.
BMJ Open. 2024;14:e087399.
PubMed Abstract available

QING H, Huang YZ, Yang E, Wei YL, et al
Impact of primary care and public health integration of chronic conditions in China: a protocol for a prospective multicentre cohort study.
BMJ Open. 2024;14:e087169.
PubMed Abstract available

COSTELLO RE, Pedersen L, Henderson AD, Tazare J, et al
Impacts of the COVID-19 pandemic on deprivation-level differences in cardiovascular hospitalisations: a comparison of England and Denmark using the OpenSAFELY platform and National Registry Data.
BMJ Open. 2024;14:e088710.
PubMed Abstract available

TANG Y, Li L, Chen S, Xue Y, et al
Hybrid versus catheter ablation for Hypertrophic CardioMyopathy with Atrial Fibrillation (HCM-AF): study protocol for a randomised controlled trial.
BMJ Open. 2024;14:e089284.
PubMed Abstract available

XU J, Liu B, Shang G, Liu S, et al
Deep brain stimulation versus vagus nerve stimulation for the motor function of poststroke hemiplegia: study protocol for a multicentre randomised controlled trial.
BMJ Open. 2024;14:e086098.
PubMed Abstract available

September 2024

IBRAHIM S, Bielecki J, Kocabas E, Singh S, et al
Lifestyle approaches to hypertension for prevention of stroke and vascular cognitive impairment: a realist review protocol.
BMJ Open. 2024;14:e088631.
PubMed Abstract available

PALMER D, Henze L, Murua Escobar H, Walter U, et al
Multicohort study testing the generalisability of the SASKit-ML stroke and PDAC prognostic model pipeline to other chronic diseases.
BMJ Open. 2024;14:e088181.
PubMed Abstract available

WANG M, Ni J, Lin B, Huang J, et al
Clinical efficacy and therapeutic mechanism of active 'five-tone' speech therapy compared with conventional speech-language therapy for treatment of post-stroke aphasia: protocol for a randomised controlled trial.
BMJ Open. 2024;14:e082282.
PubMed Abstract available

FICHEUX M, Peyro-Saint-Paul L, Balayn D, Lecrux B, et al
Safety and efficacy of apixaban versus warfarin in peritoneal dialysis patients with non-valvular atrial fibrillation: protocol for a prospective, randomised, open-label, blinded endpoint trial (APIDP2).
BMJ Open. 2024;14:e089353.
PubMed Abstract available

LIU Q, Liu L, Wang F, Tan L, et al
Efficacy of reminiscence therapy with different media on cognitive function and negative moods for older adult patients who had a stroke: protocol of a network meta-analysis.
BMJ Open. 2024;14:e078526.
PubMed Abstract available

YU P, Liu Y, Wang H, Peng T, et al
Scientific evidence of acupuncture for post-stroke motor impairment: protocol for an overview of systematic reviews and meta-analyses.
BMJ Open. 2024;14:e086427.
PubMed Abstract available

CHEN J, Lin Z, Chen S, He J, et al
Investigating combined acupuncture and transcranial direct current stimulation in patients with poststroke shoulder pain from China: protocol for a randomised controlled trial.
BMJ Open. 2024;14:e083986.
PubMed Abstract available

POTT C, Dreischulte T, Koller D, Fegl M, et al
Development of an interprofessional diagnostic toolkit to enhance outside walking gait-related participation of people after stroke in Germany: study protocol of an ongoing multi-methods study.
BMJ Open. 2024;14:e084316.
PubMed Abstract available

GERRITSEN JKW, Young JS, Krieg SM, Jungk C, et al
Resection versus biopsy in patients with glioblastoma (RESBIOP study): study protocol for an international multicentre prospective cohort study (ENCRAM 2202).
BMJ Open. 2024;14:e081689.
PubMed Abstract available

WILKINSON C, Moloney S, McClelland G, Todd A, et al
Actioning atrial fibrillation identified by ambulance services in England: a qualitative exploration.
BMJ Open. 2024;14:e078777.
PubMed Abstract available

SCHLICHTIGER J, Struven A, Massberg S, von Degenfeld G, et al
Evaluation of a digital therapy programme for the treatment of primary arterial hypertension: eXPLORE - study protocol for a fully decentralised randomised controlled feasibility study.
BMJ Open. 2024;14:e081347.
PubMed Abstract available

August 2024

AMUASI J, Agbogbatey MK, Sarfo F, Beyuo A, et al
Protocol for a mixed-methods study to explore implementation outcomes of the Phone-based Interventions under Nurse Guidance after Stroke (PINGS-II) across 10 hospitals in Ghana.
BMJ Open. 2024;14:e084584.
PubMed Abstract available

YAN H, Wang W, Li Y, Qi Y, et al
Effect of henagliflozin on left ventricular mass index in dialysis patients with HFpEF (HELD-HF): protocol for a multicentre, randomised, double-blind, placebo-controlled trial.
BMJ Open. 2024;14:e087617.
PubMed Abstract available

CARCEL C, Clancy L, Harris K, Peters R, et al
Randomised controlled decentralised feasibility trial of a fixed low-dose combination antihypertensive drug strategy to attenuate cognitive decline in high-risk adults.
BMJ Open. 2024;14:e080862.
PubMed Abstract available

CHAO G, Zhang L, Zhan Z, Bao Y, et al
Effect of multimorbidity on depressive status in older Chinese adults: evidence from the China Health and Retirement Longitudinal Study (CHARLS).
BMJ Open. 2024;14:e081776.
PubMed Abstract available

REES P, Gale C, Battersby C, Williams C, et al
Childhood Health and Educational outcomes afteR perinatal Brain injury (CHERuB): protocol for a population-matched cohort study.
BMJ Open. 2024;14:e089510.
PubMed Abstract available

TANG WK, Hui ESK, Leung WH
Cortical-striatal network functional connectivity markers in poststroke fatigue: a single-centre fMRI case-control study protocol.
BMJ Open. 2024;14:e081800.
PubMed Abstract available

SHAW L, Burgess D, Dixit A, Gaude E, et al
Rapid Assay Diagnostic for Acute Stroke Recognition (RADAR): study protocol for a diagnostic accuracy study.
BMJ Open. 2024;14:e087130.
PubMed Abstract available

KUCAB M, Keown-Stoneman CDG, Birken C, Perlman M, et al
Centre-based childcare in early childhood and child obesity: systematic review and meta-analysis protocol.
BMJ Open. 2024;14:e078116.
PubMed Abstract available

MARQUIS-GRAVEL G, Mulder H, Wruck LM, Benziger CP, et al
Impact of aspirin dose according to race in secondary prevention of atherosclerotic cardiovascular disease: a secondary analysis of the ADAPTABLE randomised controlled trial.
BMJ Open. 2024;14:e078197.
PubMed Abstract available

HERVAS C, Peiroten I, Gonzalez L, Alonso de Lecinana M, et al
Glycaemia and ischaemia-reperfusion brain injury in patients with ischaemic stroke treated with mechanical thrombectomy (GLIAS-MT): an observational, unicentric, prospective study protocol.
BMJ Open. 2024;14:e086745.
PubMed Abstract available

ALVARADO SANCHEZ JI, Montanez-Narino AV, Cardenas-Bolivar YR, Stozitzky-Rios MV, et al
Efficacy and safety of dynamic arterial elastance for weaning vasopressor support in septic shock patients: a randomised controlled trial protocol.
BMJ Open. 2024;14:e086388.
PubMed Abstract available

QI Y, Zhang H, Zhao J, Yuan D, et al
Safety and efficacy of drug-eluting stents versus heparin-bonded stents in treatment of femoropopliteal peripheral artery disease: study protocol for a multicentre, prospective randomised controlled trial in China (ELITE trial).
BMJ Open. 2024;14:e080560.
PubMed Abstract available

HUANG G, Wang H, Zhao W, Qian Y, et al
Effects of the intermittent theta burst stimulation on gait, balance and lower limbs motor function in stroke: study protocol for a double-blind randomised controlled trial with multimodal neuroimaging assessments.
BMJ Open. 2024;14:e082019.
PubMed Abstract available

CHEN W, Li W, Wang Y, Chen D, et al
Evaluation of the knowledge, attitude and practice towards ischaemic stroke among healthcare workers in neurology and neurosurgery department: a cross-sectional study in Shaanxi province, China.
BMJ Open. 2024;14:e086482.
PubMed Abstract available

July 2024

LI Y, Li L, Qie T
Developing a nomogram model for 3-month prognosis in patients who had an acute ischaemic stroke after intravenous thrombolysis: a multifactor logistic regression model approach.
BMJ Open. 2024;14:e079428.
PubMed Abstract available

LEE P, Hargreaves E, Jiang Y, Calder A, et al
Long-term cost-effectiveness analysis of rugby fans in training-New Zealand: a body weight reduction programme for males.
BMJ Open. 2024;14:e073740.
PubMed Abstract available

PAUL R, Elango S, Chakravarthy S, Sinha A, et al
Feasibility and efficacy of virtual reality rehabilitation compared with conventional physiotherapy for upper extremity impairment due to ischaemic stroke: protocol for a randomised controlled trial.
BMJ Open. 2024;14:e086556.
PubMed Abstract available

WANG L, Zhu X, Li H, Jia B, et al
Association between blood urea nitrogen to creatinine ratio and 3-month outcome in patients with acute ischaemic stroke: a retrospective cohort study from a large healthcare system.
BMJ Open. 2024;14:e085912.
PubMed Abstract available

SATGER E, Prieur-Blanc N, Viton JM, Auquier P, et al
Effectiveness of an institution-based adapted physical activity programme versus a home-based self-management programme for chronic poststroke adults: protocol for a randomised controlled study.
BMJ Open. 2024;14:e084688.
PubMed Abstract available

ROMERO-GARCIA N, Robba C, Monleon B, Ruiz-Zarco A, et al
Neurological outcomes and mortality of hyperoxaemia in patients with acute brain injury: protocol for a systematic review and meta-analysis.
BMJ Open. 2024;14:e084849.
PubMed Abstract available

SCHADE SKOV C, Pottegard A, Harbo Andersen J, Andersen G, et al
Short-term and long-term stroke risk following SARS-CoV-2 infection in relation to disease severity: a Danish national cohort study.
BMJ Open. 2024;14:e083171.
PubMed Abstract available

AJMI SC, Kurz M, Lindner TW, Dalen I, et al
Does clinical experience influence the effects of team simulation training in stroke thrombolysis? A prospective cohort study.
BMJ Open. 2024;14:e086413.
PubMed Abstract available

ULLMAN A, Takashima M, Gibson V, Comber E, et al
Preventing adverse events during paediatric cancer treatment: protocol for a multi-site hybrid randomised controlled trial of catheter lock solutions (the CLOCK trial).
BMJ Open. 2024;14:e085637.
PubMed Abstract available

TRULLENQUE-ERIKSSON A, Tomasi C, Eeg-Olofsson K, Berglundh T, et al
Periodontitis in patients with diabetes and its association with diabetes-related complications. A register-based cohort study.
BMJ Open. 2024;14:e087557.
PubMed Abstract available

COLLEE J, Vervier J, Vandenput S, Chantraine F, et al
Low-dose aspirin prophylaxis to prevent hypertensive disorders of pregnancy after in vitro fertilisation: a scoping review protocol.
BMJ Open. 2024;14:e080353.
PubMed Abstract available

LAVALLEE P, Charles H, Labreuche J, Albers GW, et al
Assessment of smoking care by stroke specialists in patients with recent TIA and minor stroke: an international prospective registry-based cohort study.
BMJ Open. 2024;14:e078632.
PubMed Abstract available

MARANO M, Suppa A, Palmieri MG, Cecconi E, et al
Comprehensive Observational and Longitudinal study on the Outbreak of Stroke-related Spasticity focusing on the Early Onset management with Botulinum NeuroToxin (COLOSSEO-BoNT): protocol for a real-world prospective observational study on upper limb s
BMJ Open. 2024;14:e085484.
PubMed Abstract available

June 2024

MITANI H, Kondo N, Amemiya A, Tabuchi T, et al
Promotive and protective effects of community-related positive childhood experiences on adult health outcomes in the context of adverse childhood experiences: a nationwide cross-sectional survey in Japan.
BMJ Open. 2024;14:e082134.
PubMed Abstract available

DERZI SH, Dewidar O, Sabri H, Tran D, et al
Antithrombotic therapy for durable left ventricular assist devices: protocol for a living systematic review with indirect comparison/network meta-analysis.
BMJ Open. 2024;14:e080110.
PubMed Abstract available

GAO D, Chu X, Zhang Y, Yan H, et al
Statins for neuroprotection in spontaneous intracerebral haemorrhage (STATIC): protocol for a multicentre, prospective and randomised controlled trial.
BMJ Open. 2024;14:e079879.
PubMed Abstract available

SILLASSEN CDB, Kamp CB, Petersen JJ, Faltermeier P, et al
Adverse effects with semaglutide: a protocol for a systematic review with meta-analysis and trial sequential analysis.
BMJ Open. 2024;14:e084190.
PubMed Abstract available

VIMALESVARAN K, Robert D, Kumar S, Kumar A, et al
Assessing the effectiveness of artificial intelligence (AI) in prioritising CT head interpretation: study protocol for a stepped-wedge cluster randomised trial (ACCEPT-AI).
BMJ Open. 2024;14:e078227.
PubMed Abstract available

SHI J, Zhang H, Wang X, Weng J, et al
Association of perioperative glucose profiles assessed by continuous glucose monitoring (CGM) with prognosis in Chinese patients with non-ST-elevation acute coronary syndrome: a cohort study protocol.
BMJ Open. 2024;14:e079666.
PubMed Abstract available

LI S, Zhang D, Sha Y, Zhu Y, et al
Efficacy and safety of tirofiban in patients with acute branch atheromatous disease-related stroke (BRANT): a protocol for a randomised controlled trial.
BMJ Open. 2024;14:e082141.
PubMed Abstract available

HOUSTON BL, McIsaac DI, Breau RH, Andrews M, et al
Hospital policy of tranexamic acid to reduce transfusion in major non-cardiac surgery (TRACTION): protocol for a phase IV randomised controlled trial.
BMJ Open. 2024;14:e084847.
PubMed Abstract available

May 2024

ZHOU LY, Peng LJ, Liu YF, Wang SW, et al
Transcutaneous auricular vagal nerve stimulation for consciousness recovery in patients with prolonged disorders of consciousness (TAVREC): study protocol for a multicenter, triple-blind, randomized controlled trial in China.
BMJ Open. 2024;14:e083888.
PubMed Abstract available

EVANS R, Douglas J, Winkler D, Cubis L, et al
Understanding the interaction between support and social participation for people with physical disabilities: a scoping review protocol.
BMJ Open. 2024;14:e083102.
PubMed Abstract available

BOUCHER E, Jell A, Singh S, Davies J, et al
Protocol for the Development and Analysis of the Oxford and Reading Cognitive Comorbidity, Frailty and Ageing Research Database-Electronic Patient Records (ORCHARD-EPR).
BMJ Open. 2024;14:e085126.
PubMed Abstract available

LIU C, Chong MC, Lee WL, Zhang HY, et al
Perceptions and self-management of a healthy diet among middle-aged adults with risk of stroke in North China: a qualitative exploration.
BMJ Open. 2024;14:e081840.
PubMed Abstract available

ANEMAAT LN, Palmer VJ, Copland DA, Binge G, et al
Understanding experiences, unmet needs and priorities related to post-stroke aphasia care: stage one of an experience-based co-design project.
BMJ Open. 2024;14:e081680.
PubMed Abstract available

BRUUN-JENSEN M, Winther S, Schmidt SE, Moller Dahl C, et al
DARE-ISC model for prediction of 1-year ischaemic stroke risk in the general population and atrial fibrillation patients: a Danish nationwide cohort study.
BMJ Open. 2024;14:e076640.
PubMed Abstract available

HUANG J, Ren J, Xie W, Pan R, et al
Personalised functional imaging-guided multitarget continuous theta burst stimulation for post-stroke aphasia: study protocol for a randomised controlled trial.
BMJ Open. 2024;14:e081847.
PubMed Abstract available

ZHAO B, Wang Y, Xu N, Xu J, et al
Knowledge, attitude and practice of poststroke depression among patients with poststroke depression and their family members in Heilongjiang Province, China: a cross-sectional study.
BMJ Open. 2024;14:e078276.
PubMed Abstract available

XU Q, Ge Q, Shi L, Zhang Y, et al
Assessing the mediating role of family resilience between caregiver burden and caregiver capacity: a cross-sectional study among Chinese stroke survivors and family caregivers in a real-world setting.
BMJ Open. 2024;14:e083106.
PubMed Abstract available

KARIM N, Hod R, Wahab MIA, Ahmad N, et al
Projecting non-communicable diseases attributable to air pollution in the climate change era: a systematic review.
BMJ Open. 2024;14:e079826.
PubMed Abstract available

PERKS J, McBride P, Mansoubi M, Clatworthy P, et al
EvolvRehab-MoveWell telerehabilitation for stroke survivors: study protocol for a feasibility with embedded initial proof-of-concept study.
BMJ Open. 2024;14:e078104.
PubMed Abstract available

BEREHAN HB, Dessie ZG, Tesfaw LM
Exploring functional abilities and competing risks among stroke patients: a longitudinal and survival analysis study at Felege Hiwot Referral Hospital, Ethiopia.
BMJ Open. 2024;14:e073384.
PubMed Abstract available

April 2024

SILVA PINTO S, Henriques TS, Teixeira ASC, Monteiro H, et al
Appropriateness of prescribing profiles and intake adherence to non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation: analysis of a retrospective longitudinal study using real-world data from Northern Portugal (AF-React St
BMJ Open. 2024;14:e076108.
PubMed Abstract available

LUANGSINSIRI C, Thavorncharoensap M, Chaikledkaew U, Pattanaprateep O, et al
Lifetime costs of alcohol consumption in Thailand: protocol for an incidence-based cost-of-illness study using Markov model.
BMJ Open. 2024;14:e079829.
PubMed Abstract available

GERRITSEN JKW, Young JS, Chang SM, Krieg SM, et al
SUPRAMAX-study: supramaximal resection versus maximal resection for glioblastoma patients: study protocol for an international multicentre prospective cohort study (ENCRAM 2201).
BMJ Open. 2024;14:e082274.
PubMed Abstract available

MANT J, Modi RN, Dymond A, Armstrong N, et al
Randomised controlled trial of population screening for atrial fibrillation in people aged 70 years and over to reduce stroke: protocol for the SAFER trial.
BMJ Open. 2024;14:e082047.
PubMed Abstract available

ZIMMERMAN KA, Hain JA, Graham NSN, Rooney EJ, et al
Prospective cohort study of long-term neurological outcomes in retired elite athletes: the Advanced BiomaRker, Advanced Imaging and Neurocognitive (BRAIN) Health Study protocol.
BMJ Open. 2024;14:e082902.
PubMed Abstract available

ALMUBAYYIDH M, Alghamdi I, Parry-Jones AR, Jenkins D, et al
Prehospital identification of intracerebral haemorrhage: a scoping review of early clinical features and portable devices.
BMJ Open. 2024;14:e079316.
PubMed Abstract available

DURLACH O, Tripoz-Dit-Masson S, Masse-Deragon N, Subtil F, et al
Feasibility of a screening and prevention procedure for risks associated with dysphagia in older patients in geriatric units: the DYSPHAGING pilot study protocol.
BMJ Open. 2024;14:e081333.
PubMed Abstract available

LIU J, Shen L, Nguyen-Hoang L, Zhou Q, et al
Aspirin versus metformin in pregnancies at high risk of preterm pre-eclampsia in China (AVERT): protocol for a multicentre, double-blind, 3-arm randomised controlled trial.
BMJ Open. 2024;14:e074493.
PubMed Abstract available

HUTCHINSON B, Walter A, Campbell N, Whelton PK, et al
Scaling hypertension treatment in 24 low-income and middle-income countries: economic evaluation of treatment decisions at three blood pressure cut-points.
BMJ Open. 2024;14:e071036.
PubMed Abstract available

LIU W, Cheng X, Zhang Y, Liao W, et al
Effect of transcranial direct current stimulation combined with transcutaneous auricular vagus nerve stimulation on poststroke cognitive impairment: a study protocol for a randomised controlled trial.
BMJ Open. 2024;14:e082764.
PubMed Abstract available

CHEN Q, Kan M, Jiang X, Liu H, et al
Comparison of the efficacy and tolerability of different repetitive transcranial magnetic stimulation modalities for post-stroke dysphagia: a systematic review and Bayesian network meta-analysis protocol.
BMJ Open. 2024;14:e080289.
PubMed Abstract available

RASYID A, Harris S, Kurniawan M, Mesiano T, et al
Predictive value of admission D-dimer levels in patient with acute ischaemic stroke and COVID-19: a second-wave prospective cohort study.
BMJ Open. 2024;14:e077500.
PubMed Abstract available

ALAMER AA, Ward C, Forrest I, Drinnan M, et al
Eating and drinking experience in patients with idiopathic pulmonary fibrosis: a qualitative study.
BMJ Open. 2024;14:e078608.
PubMed Abstract available

LI B, Niu T, Dai Y, Bu L, et al
Intraoperative intensive blood pressure management strategy and the outcome of patients who had an acute ischaemic stroke undergoing endovascular treatment under general anaesthesia: study protocol for a prospective randomised controlled trial.
BMJ Open. 2024;14:e079197.
PubMed Abstract available

March 2024

YIN Z, Deng Y, Li Z, Gu H, et al
Assessment of rehabilitation following acute ischaemic stroke in China: a registry-based retrospective observational study.
BMJ Open. 2024;14:e082279.
PubMed Abstract available

SHI R, Meng W, Liu Z, Chang L, et al
Hyperbaric oxygen therapy for poststroke insomnia: a systematic review and meta-analysis protocol.
BMJ Open. 2024;14:e081642.
PubMed Abstract available

GUPTA R, Sharma K, Khedar RS, Sharma SK, et al
Influence of COVID-19 pandemic in India on coronary artery disease clinical presentation, angiography, interventions and in-hospital outcomes: a single centre prospective registry-based observational study.
BMJ Open. 2024;14:e078596.
PubMed Abstract available

CHEN F, Li G, Zhang X, Shen Q, et al
impHFrEF trial: study protocol for an open-label, multicentre study of improvement the outcome of patients with heart failure in China using a mobile hEalth-supported platForm.
BMJ Open. 2024;14:e081011.
PubMed Abstract available

MORTENSEN JK, Blauenfeldt RA, Hedegaard JN, Morberg Wejse C, et al
Prevalence and impact of SARS-CoV-2 infection among patients with acute ischaemic stroke: a nationwide register-based cohort study in Denmark.
BMJ Open. 2024;14:e081527.
PubMed Abstract available

UEMATSU T, Nojiri S, Ishijima M, Nishizaki Y, et al
Association between osteoarthritis and cardiovascular disease in elderly in Japan: an administrative claims database analysis.
BMJ Open. 2024;14:e080387.
PubMed Abstract available

GU Y, Xie J, Liu X, Zhou X, et al
Nomogram for predicting moderate-to-severe sleep-disordered breathing in patients with acute ischaemic stroke: a retrospective cohort study.
BMJ Open. 2024;14:e076709.
PubMed Abstract available

RIJK MH, Platteel TN, van den Berg TMC, Geersing GJ, et al
Prognostic factors and prediction models for hospitalisation and all-cause mortality in adults presenting to primary care with a lower respiratory tract infection: a systematic review.
BMJ Open. 2024;14:e075475.
PubMed Abstract available

HARVEY S, Stone M, Zingelman S, Copland DA, et al
Comprehensive quality assessment for aphasia rehabilitation after stroke: protocol for a multicentre, mixed-methods study.
BMJ Open. 2024;14:e080532.
PubMed Abstract available

BURTON E, Quinn R, Crosbie-Staunton K, Deasy C, et al
Temporal trends of ambulance time intervals for suspected stroke/transient ischaemic attack (TIA) before and during the COVID-19 pandemic in Ireland: a quasi-experimental study.
BMJ Open. 2024;14:e078168.
PubMed Abstract available

ZHU A, Tang R, Rajendran S, Hajian H, et al
Prescriber decision-making on antithrombotic therapy after endovascular intervention for peripheral artery disease: a protocol for a discrete choice experiment.
BMJ Open. 2024;14:e079668.
PubMed Abstract available

VAN PAASSEN JG, Tan JP, Deneer VHM, Bouvy ML, et al
Exploring the pharmacists' role in optimising antithrombotic therapy in primary care: a qualitative study.
BMJ Open. 2024;14:e079018.
PubMed Abstract available

BANSAL S, Canziani MEF, Birne R, Anker SD, et al
Finerenone cardiovascular and kidney outcomes by age and sex: FIDELITY post hoc analysis of two phase 3, multicentre, double-blind trials.
BMJ Open. 2024;14:e076444.
PubMed Abstract available

JULLIAND S, Papaxanthis C, Delphin C, Mock A, et al
IMPROVE study protocol, investigating post-stroke local muscle vibrations to promote cerebral plasticity and functional recovery: a single-blind randomised controlled trial.
BMJ Open. 2024;14:e079918.
PubMed Abstract available

EINARSDOTTIR MJ, Kibiwott Kirui B, Li H, Olsson D, et al
Impact of chronic oral glucocorticoid treatment on mortality in patients with COVID-19: analysis of a population-based cohort.
BMJ Open. 2024;14:e080640.
PubMed Abstract available

MA J, Tian Z, Chai P, Wan Q, et al
Estimating the economic burden of stroke in China: a cost-of-illness study.
BMJ Open. 2024;14:e080634.
PubMed Abstract available

REDER SR, Herrlich N, Grauhan NF, Othman AE, et al
Sex-specific Impact of the first COVID-19 Lockdown on Age Structure and Case Acuity at Admission in a Patient Population in southwestern Germany: a retrospective comparative Study in Neuroradiology.
BMJ Open. 2024;14:e079625.
PubMed Abstract available

SHEN Z, Mi S, Huang C, Zhou D, et al
Home-based mobile-guided exercise-based cardiac rehabilitation among patients undergoing transcatheter aortic valve replacement (REHAB-TAVR): protocol for a randomised clinical trial.
BMJ Open. 2024;14:e080042.
PubMed Abstract available

YU C, Li H, Lei C, Wang Y, et al
Epicardial left atrial appendage clipping versus direct oral anticoagulant to reduce stroke risk in non-paroxysmal atrial fibrillation (LAA-CLIP): rationale, design and study protocol for a multicentre randomised controlled trial.
BMJ Open. 2024;14:e083153.
PubMed Abstract available

VAHLBERG BM, Eriksson S, Holmback U, Lundstrom E, et al
Factors associated with changes in walking performance in individuals 3 months after stroke or TIA: secondary analyses from a randomised controlled trial of SMS-delivered training instructions in Sweden.
BMJ Open. 2024;14:e078180.
PubMed Abstract available

February 2024

NGUYEN B, Marshall JL, Rana C, Atem FD, et al
Prospective study examining the impact of cerebral angiography on quantitative pupillometer values in the interventional radiology suite.
BMJ Open. 2024;14:e080779.
PubMed Abstract available

LOTT N, Douglas JL, Magnusson M, Gani J, et al
Should intermittent pneumatic compression devices be standard therapy for the prevention of venous thromboembolic events in major surgery? Protocol for a randomised clinical trial (IMPOSTERS).
BMJ Open. 2024;14:e078913.
PubMed Abstract available

GHAITH AK, El-Hajj VG, Atallah E, Rios Zermeno J, et al
Impact of the pandemic and concomitant COVID-19 on the management and outcomes of middle cerebral artery strokes: a nationwide registry-based study.
BMJ Open. 2024;14:e080738.
PubMed Abstract available

BURLAKOTI A, Kumaratilake J, Taylor J, Henneberg M, et al
Trend of cerebral aneurysms over the past two centuries: need for early screening.
BMJ Open. 2024;14:e081290.
PubMed Abstract available

BALLEGAARD ELF, Lindhard K, Lindhardt M, Peters CD, et al
Protocol for a randomised controlled trial comparing warfarin with no oral anticoagulation in patients with atrial fibrillation on chronic dialysis: the Danish Warfarin-Dialysis (DANWARD) trial.
BMJ Open. 2024;14:e081961.
PubMed Abstract available

SHAW L, Briscoe S, Nunns MP, Lawal HM, et al
What is the quantity, quality and type of systematic review evidence available to inform the optimal prescribing of statins and antihypertensives? A systematic umbrella review and evidence and gap map.
BMJ Open. 2024;14:e072502.
PubMed Abstract available

MCCORMICK S, Jarvis JM, Terhorst L, Richardson A, et al
Patient-report and caregiver-report measures of rehabilitation service use following acquired brain injury: a systematic review.
BMJ Open. 2024;14:e076537.
PubMed Abstract available

HERNANDEZ-PINILLA A, Clua-Espuny JL, Satue-Gracia EM, Palleja-Millan M, et al
Protocol for a multicentre and prospective follow-up cohort study of early detection of atrial fibrillation, silent stroke and cognitive impairment in high-risk primary care patients: the PREFA-TE study.
BMJ Open. 2024;14:e080736.
PubMed Abstract available

BELANGER A, Beaudet L, Lapointe T, Houle J, et al
Clinical and organisational quality indicators for the optimal management of acute ischaemic stroke in the era of thrombectomy: a scoping review and expert consensus study.
BMJ Open. 2024;14:e073173.
PubMed Abstract available

CARTON DE TOURNAI A, Herman E, Gathy E, Ebner-Karestinos D, et al
Baby HABIT-ILE intervention: study protocol of a randomised controlled trial in infants aged 6-18 months with unilateral cerebral palsy.
BMJ Open. 2024;14:e078383.
PubMed Abstract available

ULEBERG B, Bonaa KH, Govatsmark RES, Olsen F, et al
Exploring variation in timely reperfusion treatment in ST-segment elevation myocardial infarction in Norway: a national register-based cohort study.
BMJ Open. 2024;14:e081301.
PubMed Abstract available

WANG W, You M, Ma W, Yang Y, et al
Effect of eye-tracking-based attention training for patients with poststroke cognitive impairment: a study protocol for a prospective, single-blinded, single-centre, randomised controlled trial in China.
BMJ Open. 2024;14:e079917.
PubMed Abstract available

SHIRAISHI Y, Ikemura N, Urashima M, Kohno T, et al
Rationale and protocol of the LAQUA-HF trial: a factorial randomised controlled trial evaluating the effects of neurohormonal and diuretic agents on health-status reported outcomes in heart failure patients.
BMJ Open. 2024;14:e076519.
PubMed Abstract available

LEWIS J, Evison F, Doal R, Field J, et al
How far back do we need to look to capture diagnoses in electronic health records? A retrospective observational study of hospital electronic health record data.
BMJ Open. 2024;14:e080678.
PubMed Abstract available

WEIGHTMAN M, Robinson B, Mitchell MP, Garratt E, et al
Sleep and motor learning in stroke (SMiLES): a longitudinal study investigating sleep-dependent consolidation of motor sequence learning in the context of recovery after stroke.
BMJ Open. 2024;14:e077442.
PubMed Abstract available

WANG X, Zhang ZX, Lin BL, Jiang H, et al
Mediation role of perceived social support between recurrence risk perception and health behaviour among patients with stroke in China: a cross-sectional study.
BMJ Open. 2024;14:e079812.
PubMed Abstract available

HUANG CY, Huang MC, Liao HH, Lin CL, et al
Effect of acupuncture on ischaemic stroke in patients with rheumatoid arthritis: a nationwide propensity score-matched study.
BMJ Open. 2024;14:e075218.
PubMed Abstract available

WANICHANON W, Ananchaisarp T, Buathong N, Choomalee K, et al
Knowledge and attitude towards stroke among the population of one rural community in southern Thailand: a survey.
BMJ Open. 2024;14:e080269.
PubMed Abstract available

JU F, Yuan X, Sun H
Left atrial appendage occlusion for patients with valvular diseases without atrial fibrillation (the OPINION Study): study protocol for a multicentre, randomised controlled trial.
BMJ Open. 2024;14:e076688.
PubMed Abstract available

LEE YJ, Taft A, Stevenson DK, Darmstadt GL, et al
Integrating evidence and causal mapping of factors that influence medication decision-making by pregnant women at risk of hypertensive disorder: protocol for a scoping review.
BMJ Open. 2024;14:e074775.
PubMed Abstract available

ZHU F, Xu X, Jin M, Chen J, et al
Priming transcranial direct current stimulation for improving hemiparetic upper limb in patients with subacute stroke: study protocol for a randomised controlled trial.
BMJ Open. 2024;14:e079372.
PubMed Abstract available

KRISTJANSEN KA, Engel Krag A, Schmidt H, Holmich LR, et al
Perioperative treatment with tranexamic acid in melanoma (PRIME): protocol for a Danish multicentre randomised controlled trial investigating the prognostic and treatment-related impact of the plasminogen-plasmin pathway.
BMJ Open. 2024;14:e077012.
PubMed Abstract available

January 2024

GUO C, Jiang Z, He J, Ma H, et al
Impact of left atrial appendage thrombus location on diagnostic accuracy of cardiac CT: a single-centre case-control study.
BMJ Open. 2024;14:e079876.
PubMed Abstract available

FOSCHI M, Galante A, Ornello R, Necozione S, et al
Point-Of-Care low-field MRI in acute Stroke (POCS): protocol for a multicentric prospective open-label study evaluating diagnostic accuracy.
BMJ Open. 2024;14:e075614.
PubMed Abstract available

CHAO X, Wang J, Dong Y, Fang Y, et al
Neuroimaging of neuropsychological disturbances following ischaemic stroke (CONNECT): a prospective cohort study protocol.
BMJ Open. 2024;14:e077799.
PubMed Abstract available

LI D, Zhou M, Zha F, Long J, et al
Association between N-terminal pro-B-type natriuretic peptide and clinical outcomes in bedridden patients with stroke: a cross-sectional study.
BMJ Open. 2024;14:e077083.
PubMed Abstract available

KIM SG, Cho JM, Han K, Joo KW, et al
Non-indicated initiation of proton pump inhibitor and risk of adverse outcomes in patients with underlying chronic kidney disease: a nationwide, retrospective, cohort study.
BMJ Open. 2024;14:e078032.
PubMed Abstract available

GRIFFITHS J, Fox L, Williamson PR
Quantifying the carbon footprint of clinical trials: guidance development and case studies.
BMJ Open. 2024;14:e075755.
PubMed Abstract available

INAGUMA D, Tatematsu Y, Okamoto N, Ogata S, et al
Multicentre, open-label, randomised, controlled trial to compare early intervention with calcimimetics and conventional therapy in preventing coronary artery calcification in patients with secondary hyperparathyroidism (UPCOMING): a study protocol.
BMJ Open. 2024;14:e076962.
PubMed Abstract available

BRAY EP, Georgiou RF, Hives L, Iqbal N, et al
Non-pharmacological interventions for the reduction and maintenance of blood pressure in people with prehypertension: a systematic review protocol.
BMJ Open. 2024;14:e078189.
PubMed Abstract available

NAKAO YM, Nadarajah R, Shuweihdi F, Nakao K, et al
Predicting incident heart failure from population-based nationwide electronic health records: protocol for a model development and validation study.
BMJ Open. 2024;14:e073455.
PubMed Abstract available

BRODERICK M, Burridge J, Demain S, Johnson L, et al
Multicentre pilot randomised control trial of a self-directed exergaming intervention for poststroke upper limb rehabilitation: research protocol.
BMJ Open. 2024;14:e077121.
PubMed Abstract available

KILBRIDE C, Butcher T, Warland A, Ryan J, et al
Rehabilitation via HOMe-Based gaming exercise for the Upper limb post Stroke (RHOMBUS): a qualitative analysis of participants' experience.
BMJ Open. 2024;14:e075821.
PubMed Abstract available

GLARGAARD S, Thomsen JH, Logstrup BB, Schou M, et al
Thoracentesis to alleviate pleural effusion in acute heart failure: study protocol for the multicentre, open-label, randomised controlled TAP-IT trial.
BMJ Open. 2024;14:e078155.
PubMed Abstract available

YUAN J, Yang L, Li M, Bai J, et al
Protocol of the development of a core outcome set for stroke in multidimensional value assessment of traditional Chinese medicine.
BMJ Open. 2024;14:e079492.
PubMed Abstract available

LEITNER MA, Hubert GJ, Paternoster L, Leitner MI, et al
Clinical outcome of rural in-hospital-stroke patients after interhospital transfer for endovascular therapy within a telemedical stroke network in Germany: a registry-based observational study.
BMJ Open. 2024;14:e071975.
PubMed Abstract available

DENG YM, Sun JJ, Gu HQ, Yang KX, et al
Predictors of dysphagia screening and pneumonia among patients with intracerebral haemorrhage in China: a cross-sectional hospital-based retrospective study.
BMJ Open. 2024;14:e073977.
PubMed Abstract available

CARR E, Whiston A, O'Reilly S, O Donoghue M, et al
Sequential multiple assignment randomised trial to develop an adaptive mobile health intervention to increase physical activity in people poststroke in the community setting in Ireland: TAPAS trial protocol.
BMJ Open. 2024;14:e072811.
PubMed Abstract available

ETMINANI F, Sandgren E, Holm J, Magnusson P, et al
Randomised, siteless study to compare systematic atrial fibrillation screening using enrichment by a risk prediction model with standard care in a Swedish population aged >/= 65 years: CONSIDERING-AF study design.
BMJ Open. 2024;14:e080639.
PubMed Abstract available

LOK CE, Hemmelgarn BR, Moist LM, Polkinghorne K, et al
Protection against Incidences of Serious Cardiovascular Events Study with daily fish oil supplementation in dialysis patients (PISCES): protocol for a randomised controlled trial.
BMJ Open. 2024;14:e072239.
PubMed Abstract available

LESAINE E, Francis F, Domecq S, Miganeh-Hadi S, et al
Social and clinical vulnerability in stroke and STEMI management during the COVID-19 pandemic: a registry-based study.
BMJ Open. 2024;14:e073933.
PubMed Abstract available

December 2023

MASSEY D, Sawano M, Baker AD, Guthe DB, et al
Characterisation of internal tremors and vibration symptoms.
BMJ Open. 2023;13:e077389.
PubMed Abstract available

ZHANG Y, Jin Q, Ji C, Yuan P, et al
Innovative Telerehabilitation Enhanced Care Programme (ITECP) in young and middle-aged patients with haemorrhagic stroke to improve exercise adherence: protocol of a multicentre randomised controlled trial.
BMJ Open. 2023;13:e072268.
PubMed Abstract available

HAGBERG G, Ihle-Hansen H, Abzhandadze T, Reinholdsson M, et al
Prognostic value of acute National Institutes of Health Stroke Scale Items on disability: a registry study of first-ever stroke in the western part of Sweden.
BMJ Open. 2023;13:e080007.
PubMed Abstract available

KRISHNAMURTHY SN, Pocock S, Kaul P, Owen R, et al
Comparing the long-term outcomes in chronic coronary syndrome patients with prior ST-segment and non-ST-segment elevation myocardial infarction: findings from the TIGRIS registry.
BMJ Open. 2023;13:e070237.
PubMed Abstract available

LLOYD KE, Hall LH, Ziegler L, Foy R, et al
Acceptability of aspirin for cancer preventive therapy: a survey and qualitative study exploring the views of the UK general population.
BMJ Open. 2023;13:e078703.
PubMed Abstract available

ESTIASARI R, Tiksnadi A, Tunjungsari D, Maharani K, et al
Effectiveness of transcranial direct current stimulation (tDCS) as adjunctive treatment for chronic headache in adults with clinically stable systemic lupus erythematosus (SHADE): a randomised double-blind multiarm sham controlled clinical trial.
BMJ Open. 2023;13:e076713.
PubMed Abstract available

PARK MJ, Hwang J, Ahn J, Park SJ, et al
Ischaemic stroke in patients with diabetes requiring urgent procedures during the COVID-19 pandemic in South Korea: a retrospective, nationwide, population-based cohort study using data from the National Emergency Department Information System.
BMJ Open. 2023;13:e074381.
PubMed Abstract available

OU M, Zhu L, Chen H, Wang G, et al
Perioperative change trajectories and predictors of swallowing function and swallowing-related quality of life in patients with oral cancer: a longitudinal observational study.
BMJ Open. 2023;13:e075401.
PubMed Abstract available

LI G, Sun Y, Liu T, Yang P, et al
Predictive factors of poor outcome and mortality among anterior ischaemic stroke patients despite successful recanalisation in China: a secondary analysis of the CAPTURE trial.
BMJ Open. 2023;13:e078917.
PubMed Abstract available

DAI W, Yang X, Liu C, Ding H, et al
Effects of repetitive transcranial magnetic stimulation over the contralesional dorsal premotor cortex on upper limb function in severe ischaemic stroke: study protocol for a randomised controlled trial.
BMJ Open. 2023;13:e074037.
PubMed Abstract available

NADARAJAH R, Wu J, Arbel R, Haim M, et al
Risk of atrial fibrillation and association with other diseases: protocol of the derivation and international external validation of a prediction model using nationwide population-based electronic health records.
BMJ Open. 2023;13:e075196.
PubMed Abstract available

LIU S, Zhang K, Li X, Li C, et al
Effects of the different intensities of task-oriented training on the upper extremity motor function and self-care ability of stroke survivors: study protocol for a multiarm parallel-group randomised controlled trial in a tertiary hospital in China.
BMJ Open. 2023;13:e074106.
PubMed Abstract available

PATOMELLA AH, Guidetti S, Hagstromer M, Olsson CB, et al
Make My Day: primary prevention of stroke using engaging everyday activities as a mediator of sustainable health - a randomised controlled trial and process evaluation protocol.
BMJ Open. 2023;13:e072037.
PubMed Abstract available

ADHIKARI S, Mukhyopadhyay A, Kolzoff S, Li X, et al
Cohort profile: a large EHR-based cohort with linked pharmacy refill and neighbourhood social determinants of health data to assess heart failure medication adherence.
BMJ Open. 2023;13:e076812.
PubMed Abstract available

November 2023

MORGAN CL, Durand A, McCormack T, Hughes E, et al
Risk of major adverse cardiovascular events associated with elevated low-density lipoprotein cholesterol in a population with atherosclerotic cardiovascular disease with and without type 2 diabetes: a UK database analysis using the Clinical Practice R
BMJ Open. 2023;13:e064541.
PubMed Abstract available

SUN Y, Luo J, Gong H, Xu R, et al
Comparison of drug-coated balloon angioplasty versus standard medical therapy on recurrent stroke and mortality rates among patients with symptomatic intracranial atherosclerotic stenosis: protocol for a systematic review and meta-analysis.
BMJ Open. 2023;13:e078040.
PubMed Abstract available

GRUIA DC, Trender W, Hellyer P, Banerjee S, et al
IC3 protocol: a longitudinal observational study of cognition after stroke using novel digital health technology.
BMJ Open. 2023;13:e076653.
PubMed Abstract available

LIU M, Zhao J, Li S, Han J, et al
Early monitoring of intravenous thrombolysis in acute ischaemic stroke using wearable intelligent vital sign devices: protocol for a prospective, multicentre, observational registry cohort study.
BMJ Open. 2023;13:e074855.
PubMed Abstract available

WEI C, Wu Q, Liu J, Wang Y, et al
Key CT markers for predicting haemorrhagic transformation after ischaemic stroke: a prospective cohort study in China.
BMJ Open. 2023;13:e075106.
PubMed Abstract available

ENGDAHL J, Straat K, Isaksson E, Rooth E, et al
Multicentre, national, investigator-initiated, randomised, parallel-group, register-based superiority trial to compare extended ECG monitoring versus standard ECG monitoring in elderly patients with ischaemic stroke or transient ischaemic attack and t
BMJ Open. 2023;13:e073470.
PubMed Abstract available

CLARK B, Truman J, Whitall J, Hughes AM, et al
Why do some people who had a stroke not receive the recommended 45 min of occupational therapy and physiotherapy? A Delphi study.
BMJ Open. 2023;13:e072276.
PubMed Abstract available

CLARK B, Burridge J, Whitall J, Turk R, et al
Why do some people with stroke not receive the recommended 45 min of occupational therapy and physiotherapy after stroke? A qualitative study using focus groups.
BMJ Open. 2023;13:e072275.
PubMed Abstract available

TSZE DS, Kuppermann N, Casper TC, Barney BJ, et al
Stratification of risk for emergent intracranial abnormalities in children with headaches: a Pediatric Emergency Care Applied Research Network (PECARN) study protocol.
BMJ Open. 2023;13:e079040.
PubMed Abstract available

SALAZAR-CIFUENTES P, Contreras T, Hernandez E, Leiva-Abarca E, et al
Evaluation of ALBA device for upper extremity motor function in adults with subacute and chronic acquired brain injury: a randomised controlled trial protocol in a tertiary clinic of the metropolitan region of Chile.
BMJ Open. 2023;13:e076774.
PubMed Abstract available

LI J, Kong X, Wang J, Zhu H, et al
Family functioning and patients' depressive symptoms: comparison in perceived family function between patients who had an acute ischaemic stroke and their primary family caregivers - a cross-sectional study.
BMJ Open. 2023;13:e068794.
PubMed Abstract available

HU X, Xu H, Wang C, Wang Y, et al
Early 6 months usage of single anTiplAtelet OR anTicoAgulant followed by single antiplatelet after transcatheter aortic valve replacement: protocol for a multicentre, open-label, randomised controlled clinical trial.
BMJ Open. 2023;13:e076781.
PubMed Abstract available

SU X, Ma H, Lin S, Dou K, et al
Safety and feasibility of a real-time electronic heart team decision-making approach in patients with complex coronary artery disease: a protocol for a randomised controlled trial (EHEART trial).
BMJ Open. 2023;13:e076864.
PubMed Abstract available

STARK K, O'Leary PRE, Sakita FM, Ford JS, et al
Six month incidence of major adverse cardiovascular events among adults with HIV in northern Tanzania: a prospective observational study.
BMJ Open. 2023;13:e075275.
PubMed Abstract available

HU Z, Li W, Zhao G, Liang C, et al
Postoperative stellate ganglion block to reduce myocardial injury after laparoscopic radical resection for colorectal cancer: protocol for a randomised trial.
BMJ Open. 2023;13:e069183.
PubMed Abstract available

DONG H, Chen H, Hidru TH, Xia Y, et al
Sinus node dysfunction and stroke risk: a systematic review and meta-analysis.
BMJ Open. 2023;13:e076499.
PubMed Abstract available

LI X, Xing X, Yao N
Critical quality appraisal and algorithm development of clinical practice guidelines for management of poststroke sensory loss: a systematic review.
BMJ Open. 2023;13:e074082.
PubMed Abstract available

AL ORAIMI F, Al Rawahi A, Al Harrasi A, Albusafi S, et al
External validation of a cardiovascular risk model for Omani patients with type 2 diabetes mellitus: a retrospective cohort study.
BMJ Open. 2023;13:e071369.
PubMed Abstract available

MISHRA NK, Kwan P, Tanaka T, Sunnerhagen KS, et al
Clinical characteristics and outcomes of patients with post-stroke epilepsy: protocol for an individual patient data meta-analysis from the International Post-stroke Epilepsy Research Repository (IPSERR).
BMJ Open. 2023;13:e078684.
PubMed Abstract available

WANG W, Otieno JA, Eriksson M, Wolfe CD, et al
Developing and externally validating a machine learning risk prediction model for 30-day mortality after stroke using national stroke registers in the UK and Sweden.
BMJ Open. 2023;13:e069811.
PubMed Abstract available

XIE W, Chen X, Ma X, Song S, et al
Effect of hyperbaric oxygen therapy combined with repetitive transcranial magnetic stimulation on vascular cognitive impairment: a randomised controlled trial protocol.
BMJ Open. 2023;13:e073532.
PubMed Abstract available

BOCZAR KE, Shin S, deKemp RA, Dowlatshahi D, et al
The Canadian Study of Arterial Inflammation in Patients with Diabetes and Recent Vascular Events, Evaluation of Colchicine Effectiveness (CADENCE): protocol for a randomised, double-blind, placebo-controlled trial.
BMJ Open. 2023;13:e074463.
PubMed Abstract available

ZHANG Z, Sheng Z, Che W, An S, et al
Design and rationale of the ATTRACTIVE trial: a randomised trial of intrAThrombus Thrombolysis versus aspiRAtion thrombeCTomy during prImary percutaneous coronary interVEntion in ST-segment elevation myocardial infarction patients with high thrombus b
BMJ Open. 2023;13:e076476.
PubMed Abstract available

HELIN TA, Raatikainen P, Lehto M, Haukka J, et al
Associations of anaemia with bleeding and thrombotic complications in patients with atrial fibrillation treated with warfarin: a registry-based nested case-control study.
BMJ Open. 2023;13:e071342.
PubMed Abstract available

October 2023

FAN X, Du J, Yu H, Xu Q, et al
Hospital care experiences of female relatives caring for patients with post-stroke dysphagia during the COVID-19: a qualitative study in China.
BMJ Open. 2023;13:e068850.
PubMed Abstract available

MAKEDONOV I, Kahn S, Abdulrehman J, Schulman S, et al
TILE pilot trial study protocol: Tinzaparin Lead-in to Prevent the Post-Thrombotic syndrome study protocol.
BMJ Open. 2023;13:e064715.
PubMed Abstract available

WEBER JE, Ahmadi M, Boldt LH, Eckardt KU, et al
Protocol of the Berlin Long-term Observation of Vascular Events (BeLOVE): a prospective cohort study with deep phenotyping and long-term follow up of cardiovascular high-risk patients.
BMJ Open. 2023;13:e076415.
PubMed Abstract available

BOUGEARD M, Hauret I, Pelletier-Visa M, Plan-Paquet A, et al
Use of immersive virtual reality for stress reduction during botulinum toxin injection for spasticity (RVTOX): a study protocol of a randomised control trial.
BMJ Open. 2023;13:e066726.
PubMed Abstract available

JONES SP, Injety RJ, Pandian JD, Ratra S, et al
Healthcare professionals' perspectives of the provision of, and challenges for, eating, drinking and psychological support post stroke: findings from semistructured interviews across India.
BMJ Open. 2023;13:e069150.
PubMed Abstract available

IBRAHIM A, Legha R, Ravi R, Raj JP, et al
Association of serum magnesium levels with acute ischaemic stroke in patients with type 2 diabetes mellitus: a propensity score-matched case-control study.
BMJ Open. 2023;13:e073997.
PubMed Abstract available

WANG C, Ning YC, Song LP, Li PJ, et al
Anti-factor Xa level monitoring of low-molecular-weight heparin for prevention of venous thromboembolism in critically ill patients (AXaLPE): protocol of a randomised, open-label controlled clinical trial.
BMJ Open. 2023;13:e069742.
PubMed Abstract available

SANTOSO A, Rasiha R, Zainal ATF, Khairunnisa IN, et al
Transforming growth factor-beta and matrix metalloproteinases as potential biomarkers of fibrotic lesions induced by tuberculosis: a systematic review and meta-analysis.
BMJ Open. 2023;13:e070377.
PubMed Abstract available

JIANG T, Wang M, Hao X, Xu J, et al
Intermittent theta burst stimulation for poststroke non-spatial attention deficit: a protocol of prospective, double-blinded, single-centre, randomised controlled trial in China.
BMJ Open. 2023;13:e075131.
PubMed Abstract available

LI J, Han M, Chen Y, Wu B, et al
Prediction of recurrent ischaemic stroke using radiomics data and machine learning methods in patients with acute ischaemic stroke: protocol for a multicentre, large sample, prospective observational cohort study in China.
BMJ Open. 2023;13:e076406.
PubMed Abstract available

September 2023

WALI S, Gaitonde A, Sherman S, Min N, et al
Goal-directed versus outcome-based financial incentives for smoking cessation among low-income, hospitalised patients: rationale and design of the Financial Incentives for Smoking Treatment II (FIESTA II) randomised controlled trial.
BMJ Open. 2023;13:e074354.
PubMed Abstract available

MORRIS TA, Fernandes TM, Chung J, Vintch JRE, et al
Observational cohort study to validate SEARCH, a novel hierarchical algorithm to define long-term outcomes after pulmonary embolism.
BMJ Open. 2023;13:e074470.
PubMed Abstract available

GAO M, Xu L, Wang X, Yang X, et al
Efficacy and safety of oropharyngeal muscle strength training on poststroke oropharyngeal dysphagia: a systematic review and meta-analysis.
BMJ Open. 2023;13:e072638.
PubMed Abstract available

KOOTAR S, Huque MH, Kiely KM, Anderson CS, et al
Study protocol for development and validation of a single tool to assess risks of stroke, diabetes mellitus, myocardial infarction and dementia: DemNCD-Risk.
BMJ Open. 2023;13:e076860.
PubMed Abstract available

MORITA Y, Yoshikawa T, Takahashi M
Long working hours and risk of hypertensive intracerebral haemorrhage among Japanese workers claiming compensation for overwork-related intracerebral haemorrhage: an unmatched case-control study.
BMJ Open. 2023;13:e074465.
PubMed Abstract available

ZHENG B, Luo Y, Li Y, Gu G, et al
Prevalence and risk factors of stroke in high-altitude areas: a systematic review and meta-analysis.
BMJ Open. 2023;13:e071433.
PubMed Abstract available

ALASNAG M, Bokhari F, Almoghairi A, Marri K, et al
One-year real-world outcomes for patients undergoing transcatheter mitral valve repair: the Gulf MTEER registry (GULF Mitral Transcatheter Edge to Edge Repair).
BMJ Open. 2023;13:e073549.
PubMed Abstract available

AHMED A, Nahian MA, Rahman MM, Alam N, et al
Adult mortality trends in Matlab, Bangladesh: an analysis of cause-specific risks.
BMJ Open. 2023;13:e065146.
PubMed Abstract available

UCHIYAMA S, Suzuki-Inoue K, Wada H, Okada Y, et al
Soluble C-type lectin-like receptor 2 in stroke (CLECSTRO) study: protocol of a multicentre, prospective cohort of a novel platelet activation marker in acute ischaemic stroke and transient ischaemic attack.
BMJ Open. 2023;13:e073708.
PubMed Abstract available

PU MJ, Yu JL, Hu X, Deng L, et al
Incidence, characteristics and outcome of post-stroke recrudescence in the Chinese population: a single-centre observational study.
BMJ Open. 2023;13:e068878.
PubMed Abstract available

JOSEY K, Nethery R, Visaria A, Bates B, et al
Retrospective cohort study investigating synergism of air pollution and corticosteroid exposure in promoting cardiovascular and thromboembolic events in older adults.
BMJ Open. 2023;13:e072810.
PubMed Abstract available

JOHANSSON JF, Shannon R, Mossabir R, Airlie J, et al
Intervention to reduce sedentary behaviour and improve outcomes after stroke (Get Set Go): a study protocol for the process evaluation of a pilot cluster randomised controlled trial (RECREATE).
BMJ Open. 2023;13:e075363.
PubMed Abstract available

BADOZ M, Derimay F, Serzian G, Besutti M, et al
Incidence of atrial fibrillation in cryptogenic stroke with patent foramen ovale closure: protocol for the prospective, observational PFO-AF study.
BMJ Open. 2023;13:e074584.
PubMed Abstract available

YU T, Ren JW, Wang C, Liu SS, et al
Remote interventions for informal caregivers of patients with stroke: a systematic review and meta-analysis.
BMJ Open. 2023;13:e071461.
PubMed Abstract available

NUDY M, Galper K, George DR, Williams BA, et al
Association between diseases of despair and atherosclerotic cardiovascular disease among insured adults in the USA: a retrospective cohort study from 2017 to 2021.
BMJ Open. 2023;13:e074102.
PubMed Abstract available

ZHANG D, Liu Z, Liu P, Zhang H, et al
Association of baseline fasting plasma glucose with 1-year mortality in non-diabetic patients with acute cerebral infarction: a multicentre observational cohort study.
BMJ Open. 2023;13:e069716.
PubMed Abstract available

WANG W, Wang X, Vellone E, Zhang Z, et al
Effectiveness of a smartphone-enabled dyadic self-care programme (SDSCP) for stroke survivors and caregivers: study protocol for a randomised controlled trial.
BMJ Open. 2023;13:e073016.
PubMed Abstract available

ZORNER CR, Pallisgaard J, Schjerning AM, Jensen MK, et al
Temporal trends of hypertrophic cardiomyopathy in Denmark: a nationwide retrospective cohort study.
BMJ Open. 2023;13:e074010.
PubMed Abstract available

August 2023

CHAI K, Luo Y, Zhang M, Liu Y, et al
Effects of empagliflozin on cardiac structure, function and biomarkers in patients with heart failure with preserved ejection fraction: study protocol for a randomised, placebo-controlled prospective trial.
BMJ Open. 2023;13:e070766.
PubMed Abstract available

MITHEN LM, Weaver N, Walker FR, Inder KJ, et al
Feasibility of biomarkers to measure stress, burnout and fatigue in emergency nurses: a cross-sectional study.
BMJ Open. 2023;13:e072668.
PubMed Abstract available

WHITE K, Tate S, Zafonte R, Narayanan S, et al
SocialBit: protocol for a prospective observational study to validate a wearable social sensor for stroke survivors with diverse neurological abilities.
BMJ Open. 2023;13:e076297.
PubMed Abstract available

FUKUDA H, Hyohdoh Y, Ninomiya H, Ueba Y, et al
Impact of areal socioeconomic status on prehospital delay of acute ischaemic stroke: retrospective cohort study from a prefecture-wide survey in Japan.
BMJ Open. 2023;13:e075612.
PubMed Abstract available

ZHANG H, Xu K, Ma JY, Zhang XY, et al
Supportive care needs of patients who had a stroke: a scoping review protocol.
BMJ Open. 2023;13:e067706.
PubMed Abstract available

O'TOOLE S, Moazzez R, Wojewodka G, Zeki S, et al
Single-centre, single-blinded, randomised, parallel group, feasibility study protocol investigating if mandibular advancement device treatment for obstructive sleep apnoea can reduce nocturnal gastro-oesophageal reflux (MAD-Reflux trial).
BMJ Open. 2023;13:e076661.
PubMed Abstract available

TAYLOR E, Fusari G, Darzi A, Jones F, et al
Is a novel digital system for arm and hand rehabilitation suitable for stroke survivors? A qualitative process evaluation of OnTrack.
BMJ Open. 2023;13:e062119.
PubMed Abstract available

VOORHOUT L, Pisters R, Geurts CHPH, Oostindjer A, et al
Screening over 100 000 patients in 39 general practices in the Netherlands for anticoagulation underprescription in atrial fibrillation: a descriptive, cross-sectional study.
BMJ Open. 2023;13:e072655.
PubMed Abstract available

XU K, Zhang XY, Ma JY, Guo X, et al
Effectiveness of acceptance and commitment therapy in patients who had a stroke: a systematic review protocol.
BMJ Open. 2023;13:e069121.
PubMed Abstract available

SHARMA A, Caldeira D, Razaghizad A, Pinto FJ, et al
Cardiovascular effects of rivaroxaban in heart failure patients with sinus rhythm and coronary disease with and without diabetes: a retrospective international cohort study from COMMANDER-HF.
BMJ Open. 2023;13:e068865.
PubMed Abstract available

CHANG WH, Kim TW, Kim HS, Hanapiah FA, et al
Exoskeletal wearable robot on ambulatory function in patients with stroke: a protocol for an international, multicentre, randomised controlled study.
BMJ Open. 2023;13:e065298.
PubMed Abstract available

SIDEBOTTOM DB, Huang C, Carradice D, Holt PJ, et al
Antithrombotic drugs for cardiovascular risk reduction in patients with lower limb peripheral arterial disease: protocol for a systematic review and network meta-analysis of randomised controlled trials.
BMJ Open. 2023;13:e072355.
PubMed Abstract available

LOAN JJM, Bacon A, van Beijnum J, Bhatt P, et al
Feasibility of comparing medical management and surgery (with neurosurgery or stereotactic radiosurgery) with medical management alone in people with symptomatic brain cavernoma - protocol for the Cavernomas: A Randomised Effectiveness (CARE) pilot tr
BMJ Open. 2023;13:e075187.
PubMed Abstract available

GARAN AR, Monda KL, Dent-Acosta RE, Riskin DJ, et al
Retrospective comparison of traditional and artificial intelligence-based heart failure phenotyping in a US health system to enable real-world evidence.
BMJ Open. 2023;13:e073178.
PubMed Abstract available

VOLZ M, Mundiyanapurath S, Schauenburg H, Meuth SG, et al
Integrative-interpersonal dynamic therapy for poststroke depression (INID): study protocol of a randomised controlled pilot trial.
BMJ Open. 2023;13:e077656.
PubMed Abstract available

CROOK-RUMSEY M, Daniels SJC, Abulikemu S, Lai H, et al
Multicohort cross-sectional study of cognitive and behavioural digital biomarkers in neurodegeneration: the Living Lab Study protocol.
BMJ Open. 2023;13:e072094.
PubMed Abstract available

JIANG H, Mei Y, Lin B, Wang W, et al
Perspectives of cardiac rehabilitation in patients who had a stroke: a protocol for a qualitative study review.
BMJ Open. 2023;13:e071964.
PubMed Abstract available

FISHER RJ, Russell L, Riley-Bennett F, Cameron T, et al
Barriers and facilitators in providing home-based rehabilitation for stroke survivors with severe disability in the UK: an online focus group study with multidisciplinary rehabilitation teams.
BMJ Open. 2023;13:e071217.
PubMed Abstract available

July 2023

SANCHEZ RICO M, Plessz M, Airagnes G, Ribet C, et al
Distinct cardiovascular and cancer burdens associated with social position, work environment and unemployment: a cross-sectional and retrospective study in a large population-based French cohort.
BMJ Open. 2023;13:e074835.
PubMed Abstract available

MOSHI B, Yongolo N, Biswaro SM, Maro H, et al
Trends of frequency, mortality and risk factors among patients admitted with stroke from 2017 to 2019 to the medical ward at Kilimanjaro Christian Medical Centre hospital: a retrospective observational study.
BMJ Open. 2023;13:e071918.
PubMed Abstract available

PEREZ-ROBLEDO F, Sanchez Gonzalez JL, Bermejo-Gil BM, Llamas-Ramos R, et al
Optokinetic stimulation effects in the management of unilateral spatial neglect in patients with chronic stroke: study protocol for a randomised controlled trial.
BMJ Open. 2023;13:e070601.
PubMed Abstract available

AIRLIE J, Burton LJ, Copsey B, English C, et al
RECREATE: a study protocol for a multicentre pilot cluster randomised controlled trial (cRCT) in UK stroke services evaluating an intervention to reduce sedentary behaviour in stroke survivors (Get Set Go) with embedded process and economic evaluation
BMJ Open. 2023;13:e074607.
PubMed Abstract available

MESFIN AH, Gufue ZH, Alemayehu MA, Kedida BD, et al
Usage of cervical cancer screening services among HIV-positive women in Southern Ethiopia: a multicentre cross-sectional study.
BMJ Open. 2023;13:e068253.
PubMed Abstract available

EPPLER M, Singh N, Ding L, Magee G, et al
Discharge prescription patterns for antiplatelet and statin therapy following carotid endarterectomy: an analysis of the vascular quality initiative.
BMJ Open. 2023;13:e071550.
PubMed Abstract available

MAAS WJ, van der Zee DJ, Buskens E, Uyttenboogaart M, et al
Simulation modelling to study the impact of adding comprehensive stroke centres. Can we deliver endovascular thrombectomy sooner?
BMJ Open. 2023;13:e068749.
PubMed Abstract available

PICHLER A, Kurz A, Eichlseder M, Graf A, et al
PerIoperative iNflammatory reSponse assessment In hiGH-risk patienTs undergoing non-cardiac surgery (INSIGHT): study protocol of a prospective non-interventional observational study.
BMJ Open. 2023;13:e065469.
PubMed Abstract available

SAKAKIBARA BM, Wiley E, Barclay R, Bayley M, et al
TeleRehabilitation with Aims to Improve Lower extremity recovery in community-dwelling individuals who have had a stroke: protocol for a multisite, parallel group, assessor-blinded, randomised attention-controlled trial.
BMJ Open. 2023;13:e076723.
PubMed Abstract available

June 2023

HOBDEN G, Tang E, Demeyere N
Cognitive assessment after stroke: A qualitative study of patients' experiences.
BMJ Open. 2023;13:e072501.
PubMed Abstract available

YUAN X, Chu Q, Chen K, Wang Y, et al
Multicentre, randomised, double-blind, parallel controlled trial to investigate timing of platelet inhibition after coronary artery bypass grafting: TOP-CABG trial study.
BMJ Open. 2023;13:e070823.
PubMed Abstract available

ESTUPINAN-ROMERO F, Pinilla Dominguez J, Bernal-Delgado E
Differences in acute ischaemic stroke in-hospital mortality across referral stroke hospitals in Spain: a retrospective, longitudinal observational study.
BMJ Open. 2023;13:e068183.
PubMed Abstract available

LINDSTAD MO, Obstfelder AU, Sveen U, Stigen L, et al
Feasibility of the Perceive, Recall, Plan and Perform system of intervention for persons with brain injury in community-based rehabilitation: a pilot for a multiple-baseline design study.
BMJ Open. 2023;13:e067593.
PubMed Abstract available

BROWN L, Mossabir R, Harrison N, Lam N, et al
Developing the evidence and associated service models to support older adults living with frailty to manage their pain and to reduce its impact on their lives: protocol for a mixed-method, co-design study (The POPPY Study).
BMJ Open. 2023;13:e074785.
PubMed Abstract available

SUN Z, Lin YR, Lu MJ, Huang KY, et al
Acupuncture for gait disturbance of patients with subacute and chronic stroke: a systematic review and meta-analysis protocol.
BMJ Open. 2023;13:e071590.
PubMed Abstract available

EL-HAJJ VG, Stenimahitis V, Gharios M, Mahdi OA, et al
Spontaneous spinal cord infarctions: a systematic review and pooled analysis protocol.
BMJ Open. 2023;13:e071044.
PubMed Abstract available

WANG T, Xing Z, Gong H, Derdeyn CP, et al
Stenting versus medical therapy alone for symptomatic intracranial arterial stenosis: protocol for a systematic review and individual patient data meta-analysis.
BMJ Open. 2023;13:e071668.
PubMed Abstract available

AIROLDI C, Pagnoni F, Cena T, Ceriotti D, et al
Estimate of the prevalence of subjects with chronic diseases in a province of Northern Italy: a retrospective study based on administrative databases.
BMJ Open. 2023;13:e070820.
PubMed Abstract available

LUO J, Liao W, Lei D, Xing Z, et al
Transcarotid versus transfemoral access for cerebrovascular intervention: protocol for a systematic review and meta-analysis.
BMJ Open. 2023;13:e071820.
PubMed Abstract available

CROW J, Savage M, Gardner L, Hughes C, et al
What follow-up interventions, programmes and pathways exist for minor stroke survivors after discharge from the acute setting? A scoping review.
BMJ Open. 2023;13:e070323.
PubMed Abstract available

DE BURGOS-LUNAR C, Del Cura-Gonzalez I, Cardenas-Valladolid J, Gomez-Campelo P, et al
Validation of diagnosis of acute myocardial infarction and stroke in electronic medical records: a primary care cross-sectional study in Madrid, Spain (the e-MADVEVA Study).
BMJ Open. 2023;13:e068938.
PubMed Abstract available

MORSI RZ, Zhang Y, Carrion-Penagos J, Desai H, et al
Endovascular thrombectomy with or without thrombolysis bridging in patients with acute ischaemic stroke: protocol for a systematic review, meta-analysis of randomised trials and cost-effectiveness analysis.
BMJ Open. 2023;13:e064322.
PubMed Abstract available

KUMLUANG S, Wu O, Langhorne P, Geue C, et al
Stroke resource utilisation and all-cause mortality in Thailand 2017-2020: A retrospective, cross-sectional study.
BMJ Open. 2023;13:e072259.
PubMed Abstract available

TAN J, Gao S, Li Y, Li X, et al
Comparative effects of off-pump and multiple cardiopulmonary bypass strategies in coronary artery bypass grafting surgery: protocol for a systematic review and network meta-analysis.
BMJ Open. 2023;13:e072545.
PubMed Abstract available

ZHENG J, Hou Z, Yuan J, Zhao X, et al
Effects of intensive lipid lowering compared with moderate-intensity lipid lowering on coronary atherosclerotic plaque phenotype and major adverse cardiovascular events in adults with low to intermediate 10-year ASCVD risk (ILLUMINATION study): protoc
BMJ Open. 2023;13:e070832.
PubMed Abstract available

May 2023

HIVES L, Georgiou RF, Spencer J, Benedetto V, et al
Risk reduction intervention for raised blood pressure (REVERSE): protocol for a mixed-methods feasibility study.
BMJ Open. 2023;13:e072225.
PubMed Abstract available

FISHBANE S, Jadoul M, Dember L, Kovesdy CP, et al
Evaluation of the effect of sodium zirconium cyclosilicate on arrhythmia-related cardiovascular outcomes in patients receiving chronic haemodialysis with hyperkalaemia: protocol for the multicentre, randomised, controlled DIALIZE-Outcomes study.
BMJ Open. 2023;13:e071309.
PubMed Abstract available

EDE J, Teurneau-Hermansson K, Moseby-Knappe M, Ramgren B, et al
Carbon dioxide flooding to reduce postoperative neurological injury following surgery for acute type A aortic dissection: a prospective, randomised, blinded, controlled clinical trial, CARTA study protocol - objectives and design.
BMJ Open. 2023;13:e063837.
PubMed Abstract available

BROATCH JR, Zarekookandeh N, Glarin R, Strik M, et al
Train Smart Study: protocol for a randomised trial investigating the role of exercise training dose on markers of brain health in sedentary middle-aged adults.
BMJ Open. 2023;13:e069413.
PubMed Abstract available

BENNETT M, Pistillo A, Recalde M, Reyes C, et al
Time trends in the incidence of cardiovascular disease, hypertension and diabetes by sex and socioeconomic status in Catalonia, Spain: a population-based cohort study.
BMJ Open. 2023;13:e066404.
PubMed Abstract available

KENGNE TALLA P, Thomas A, Ataman R, Auger C, et al
Evaluating the implementation of the Mayo-Portland Adaptability Inventory-4 (MPAI-4) in three rehabilitation settings in Quebec: a mixed-methods study protocol.
BMJ Open. 2023;13:e068866.
PubMed Abstract available

JALO H, Seth M, Pikkarainen M, Haggstrom I, et al
Early identification and characterisation of stroke to support prehospital decision-making using artificial intelligence: a scoping review protocol.
BMJ Open. 2023;13:e069660.
PubMed Abstract available

BARITELLO O, Stein H, Wolff LL, Hamann M, et al
Effect of multicomponent rehabilitation on independence and functioning in elderly patients with common age-associated diseases: protocol for a scoping review (REHOLD).
BMJ Open. 2023;13:e068722.
PubMed Abstract available

TODD R, Rogers CA, Pufulete M, Culliford L, et al
Efficacy and safety of carbon dioxide insufflation for brain protection for patients undergoing planned left-sided open heart valve surgery: protocol for a multicentre, placebo-controlled, blinded, randomised controlled trial (the CO2 Study).
BMJ Open. 2023;13:e074221.
PubMed Abstract available

XIE Y, Kuang J, Li Q, Hong T, et al
Impact of polyethylene glycol loxenatide on cardiovascular outcomes in patients with type 2 diabetes: study protocol for a multicentre, randomised, double-blind, placebo-controlled trial (BALANCE-3).
BMJ Open. 2023;13:e069080.
PubMed Abstract available

BRANNMARK C, Klasson S, Stanne TM, Samuelsson H, et al
FIND Stroke Recovery Study (FIND): rationale and protocol for a longitudinal observational cohort study of trajectories of recovery and biomarkers poststroke.
BMJ Open. 2023;13:e072493.
PubMed Abstract available

WANG G, Qiao L, Tang Z, Zhou S, et al
Association between bilirubin levels and risk of stroke: a systematic review and meta-analysis.
BMJ Open. 2023;13:e064433.
PubMed Abstract available

ASKIM T, Hokstad A, Bergh E, Dohl O, et al
Multimodal individualised intervention to prevent functional decline after stroke: protocol of a randomised controlled trial on long-term follow-up after stroke (LAST-long).
BMJ Open. 2023;13:e069656.
PubMed Abstract available

KRASNIQI L, Brandes A, Mortensen PE, Dahl JS, et al
Atorvastatin and the influence on postoperative atrial fibrillation after surgical aortic valve replacement (STARC) in adults at Odense University Hospital, Denmark: study protocol for a randomised controlled trial.
BMJ Open. 2023;13:e069595.
PubMed Abstract available

SANMUGALINGHAM G, Mok E, Cafazzo JA, Desveaux L, et al
Text message-based intervention, Keeping in Touch (KiT), to support youth as they transition to adult type 1 diabetes care: a protocol for a multisite randomised controlled superiority trial.
BMJ Open. 2023;13:e071396.
PubMed Abstract available

XIANG J, He L, Peng T, Liang W, et al
Value of retrograde pulmonary vein perfusion combined with pulmonary artery thrombectomy in acute pulmonary embolism: a protocol for a systematic review and meta-analysis.
BMJ Open. 2023;13:e069685.
PubMed Abstract available

TAN SB, Tan J, Raczkowska MN, Chean Wen Lee J, et al
Digital game-based interventions for cognitive training in healthy adults and adults with cognitive impairment: protocol for a two-part systematic review and meta-analysis.
BMJ Open. 2023;13:e071059.
PubMed Abstract available

ALMUBAYYIDH M, Alghamdi I, Parry-Jones AR, Jenkins D, et al
Clinical features and novel technologies for prehospital detection of intracerebral haemorrhage: a scoping review protocol.
BMJ Open. 2023;13:e070228.
PubMed Abstract available

LI T, Feng J, Hu R, Lv M, et al
Effect and safety of C7 neurotomy at the intervertebral foramen in patients with chronic poststroke aphasia: a multicentre, randomised, controlled study protocol.
BMJ Open. 2023;13:e065173.
PubMed Abstract available

April 2023

GONCALVES M, Lima MJ, Fonseca A, Duque C, et al
Study protocol for a pilot randomised controlled trial evaluating the feasibility and effectiveness of non-pharmacological interventions to recover functionality after a transient ischaemic attack or a minor stroke: the 'Back to Normal' trial.
BMJ Open. 2023;13:e069593.
PubMed Abstract available

CROCKETT S, Hanna L, Singh A, Gunning S, et al
Carbon dioxide flushing versus saline flushing of thoracic aortic stents (INTERCEPTevar): protocol for a multicentre pilot randomised controlled trial.
BMJ Open. 2023;13:e067605.
PubMed Abstract available

GOFTON T, Dhanani S, Meade M, Boyd JG, et al
Neurologic Physiology after Removal of Therapy (NeuPaRT) study: study protocol of a multicentre, prospective, observational, pilot feasibility study of neurophysiology after withdrawal of life-sustaining measures.
BMJ Open. 2023;13:e073643.
PubMed Abstract available

BEJOT Y, Soilly AL, Bardou M, Duloquin G, et al
Efficiency and effectiveness of intensive multidisciplinary follow-up of patients with stroke/TIA or myocardial infarction compared to usual monitoring: protocol of a pragmatic randomised clinical trial. DiVa (Dijon vascular) study.
BMJ Open. 2023;13:e070197.
PubMed Abstract available

ADELAKUN AR, Turgeon RD, De Vera MA, McGrail K, et al
Oral anticoagulant switching in patients with atrial fibrillation: a scoping review.
BMJ Open. 2023;13:e071907.
PubMed Abstract available

MEDLINSKIENE K, Richardson S, Petty D, Stirling K, et al
Barriers and enablers to healthcare system uptake of direct oral anticoagulants for stroke prevention in atrial fibrillation: a qualitative interview study with healthcare professionals and policy makers in England.
BMJ Open. 2023;13:e069575.
PubMed Abstract available

DING X, Zhou H, Yue Q, Shu Z, et al
Association of trajectories of non-high-density lipoprotein cholesterol concentration with risk of cardiovascular disease: the Kailuan Study.
BMJ Open. 2023;13:e069807.
PubMed Abstract available

PARKS T, Narube L, Perman ML, Sakumeni K, et al
Population-based assessment of cardiovascular complications of rheumatic heart disease in Fiji: a record-linkage analysis.
BMJ Open. 2023;13:e070629.
PubMed Abstract available

NGUYEN TA, Mai TD, Vu LD, Dao CX, et al
Factors related to intracerebral haematoma in patients with aneurysmal subarachnoid haemorrhage in Vietnam: a multicentre prospective cohort study.
BMJ Open. 2023;13:e066186.
PubMed Abstract available

CACHAY R, Watanabe-Tejada T, Cuno K, Gil-Zacarias M, et al
Long-term impact on cardiopulmonary function and quality of life among patients recovered from SARS-CoV-2 infection in a 6-month follow-up period in Lima, Peru: FUNCTION cohort study protocol.
BMJ Open. 2023;13:e067365.
PubMed Abstract available

DOUGLAS J, Winkler D, McLeod A, Oliver S, et al
Primary healthcare needs and service utilisation of people with disability: a data linkage protocol.
BMJ Open. 2023;13:e068059.
PubMed Abstract available

EBNER-KARESTINOS D, Gathy E, Carton de Tournai A, Herman E, et al
Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) in adults with chronic stroke: protocol of a randomised controlled trial.
BMJ Open. 2023;13:e070642.
PubMed Abstract available

WIJESIRI HSMSK, Wasalathanthri S, De Silva Weliange S, Wijeyaratne CN, et al
Quality of life and its associated factors among home-dwelling older people residing in the District of Colombo, Sri Lanka: a community-based cross-sectional study.
BMJ Open. 2023;13:e068773.
PubMed Abstract available

XIANG D, Zhang ZX, Ge S, Wang WN, et al
Physio-psycho-social interaction mechanism in dyadic health of young and middle-aged stroke survivors and their spousal caregivers: a longitudinal observational study protocol.
BMJ Open. 2023;13:e065767.
PubMed Abstract available

KOFFLER D, Eckstein J, Herman J, Martins-Welch D, et al
Efficacy of ketamine mouthwash in the management of oral and pharyngeal toxicity associated with head and neck chemoradiotherapy: protocol for a phase II, Simon's two-stage trial.
BMJ Open. 2023;13:e064809.
PubMed Abstract available

KUROGI R, Kada A, Ogasawara K, Nishimura K, et al
National trends in the outcomes of subarachnoid haemorrhage and the prognostic influence of stroke centre capability in Japan: retrospective cohort study.
BMJ Open. 2023;13:e068642.
PubMed Abstract available

WEIGHTMAN M, Robinson B, Fallows R, Henry AL, et al
Improving sleep and learning in rehabilitation after stroke, part 2 (INSPIRES2): study protocol for a home-based randomised control trial of digital cognitive behavioural therapy (dCBT) for insomnia.
BMJ Open. 2023;13:e071764.
PubMed Abstract available

ZOUNGAS S, Curtis A, Spark S, Wolfe R, et al
Statins for extension of disability-free survival and primary prevention of cardiovascular events among older people: protocol for a randomised controlled trial in primary care (STAREE trial).
BMJ Open. 2023;13:e069915.
PubMed Abstract available

March 2023

VESTERGAARD SB, Damsbo AG, Blauenfeldt RA, Johnsen SP, et al
Impact of prestroke physical activity and citalopram treatment on poststroke depressive symptoms: a secondary analysis of data from the TALOS randomised controlled trial in Denmark.
BMJ Open. 2023;13:e070822.
PubMed Abstract available

LV J, Wang C, Gao X, Yang J, et al
Development and validation of dynamic models to predict postdischarge mortality risk in patients with acute myocardial infarction: results from China Acute Myocardial Infarction Registry.
BMJ Open. 2023;13:e069505.
PubMed Abstract available

ABEBE TG, Feleke SF, Dessie AM, Anteneh RM, et al
Development and internal validation of a clinical risk score for in-hospital mortality after stroke: a single-centre retrospective cohort study in Northwest Ethiopia.
BMJ Open. 2023;13:e063170.
PubMed Abstract available

COMOLLI L, Korda A, Zamaro E, Wagner F, et al
Vestibular syndromes, diagnosis and diagnostic errors in patients with dizziness presenting to the emergency department: a cross-sectional study.
BMJ Open. 2023;13:e064057.
PubMed Abstract available

GRAHAM NSN, Blissitt G, Zimmerman K, Friedland D, et al
ADVANCE-TBI study protocol: traumatic brain injury outcomes in UK military personnel serving in Afghanistan between 2003 and 2014 - a longitudinal cohort study.
BMJ Open. 2023;13:e069243.
PubMed Abstract available

VAN DEN BOSCH CH, Loeffen Y, van der Steeg AFW, van der Bruggen JT, et al
CATERPILLAR-study protocol: an assessor-blinded randomised controlled trial comparing taurolidine-citrate-heparin to heparin-only lock solutions for the prevention of central line-associated bloodstream infections in paediatric oncology patients.
BMJ Open. 2023;13:e069760.
PubMed Abstract available

VAN DUSEN RA, Abernethy K, Chaudhary N, Paudyal V, et al
Association of the COVID-19 pandemic on stroke admissions and treatment globally: a systematic review.
BMJ Open. 2023;13:e062734.
PubMed Abstract available

HALL S, Birks J, Anderson I, Bacon A, et al
Risk of Aneurysm Rupture (ROAR) study: protocol for a long-term, longitudinal, UK multicentre study of unruptured intracranial aneurysms.
BMJ Open. 2023;13:e070504.
PubMed Abstract available

TYAGI S, Luo N, Tan CS, Tan KB, et al
Qualitative study exploring heterogeneity in caregiving experiences post-stroke in Singapore.
BMJ Open. 2023;13:e055988.
PubMed Abstract available

XU YY, Chen WQ, Wang MX, Pan YS, et al
Lipid management in ischaemic stroke or transient ischaemic attack in China: result from China National Stroke Registry III.
BMJ Open. 2023;13:e069465.
PubMed Abstract available

ZHOU Z, Chen X, Li Y, Chen S, et al
Effects of integrated action and sensory observation therapy based on mirror neuron and embodied cognition theory on upper limb sensorimotor function in chronic stroke: a study protocol for a randomised controlled trial.
BMJ Open. 2023;13:e069126.
PubMed Abstract available

LAI MH, Xu HC, Huang MC, Lu Y, et al
Transcranial direct current stimulation combined with bodyweight support-tai chi footwork for motor function of stroke survivors: a study protocol of randomised controlled trial.
BMJ Open. 2023;13:e065338.
PubMed Abstract available

HARRISON P, Carr E, Goldsmith K, Young A, et al
Antidepressant Advisor (ADeSS): a decision support system for antidepressant treatment for depression in UK primary care - a feasibility study.
BMJ Open. 2023;13:e060516.
PubMed Abstract available

QIU Y, Cheng S, Wu Y, Yan W, et al
Development of rapid and effective risk prediction models for stroke in the Chinese population: a cross-sectional study.
BMJ Open. 2023;13:e068045.
PubMed Abstract available

SONG G, Yang C, Qu Z, Lin X, et al
Association between seropositivity for toxocariasis and cognitive functioning in older adults: an analysis of cross-sectional data from the US National Health and Nutrition Examination Survey (NHANES), 2011-2014.
BMJ Open. 2023;13:e068974.
PubMed Abstract available

February 2023

SHAH T, McCarthy M, Nasir I, Archer H, et al
Colchicine and high-intensity rosuvastatin in the treatment of non-critically ill patients hospitalised with COVID-19: a randomised clinical trial.
BMJ Open. 2023;13:e067910.
PubMed Abstract available

BETHLEHEM C, Bootsma IT, De Lange F, Boerma EC, et al
Identifying risk factors for perioperative decline in right ventricular performance in cardiac surgery patients: a prospective observational study in a tertiary care hospital.
BMJ Open. 2023;13:e068598.
PubMed Abstract available

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