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Articles published in BMJ Open

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Single Articles


    June 2022
  1. WANG HY, Gu HQ, Zhou Q, Jiang YY, et al
    Thrombolysis, time-to-treatment and in-hospital outcomes among young adults with ischaemic stroke in China: findings from a nationwide registry study in China.
    BMJ Open. 2022;12:e055055.
    PubMed     Abstract available


  2. TURNER GM, Jones R, Collis P, Patel S, et al
    Structured follow-up pathway to support people after transient ischaemic attack and minor stroke (SUPPORT TIA): protocol for a feasibility study and process evaluation.
    BMJ Open. 2022;12:e060280.
    PubMed     Abstract available


  3. WANG X, Liang M, Zeng F, Wang Y, et al
    Predictive role of modifiable factors in stroke: an umbrella review.
    BMJ Open. 2022;12:e056680.
    PubMed     Abstract available


  4. LI Y, Yang W, Li J, Zhang Y, et al
    Relationship between serum insulin-like growth factor 1 levels and ischaemic stroke: a systematic review and meta-analysis.
    BMJ Open. 2022;12:e045776.
    PubMed     Abstract available


  5. GAO M, Wang Y, Xu L, Wang X, et al
    Safety and performance of oropharyngeal muscle strength training in the treatment of post-stroke dysphagia during oral feeding: protocol for a systematic review and meta-analysis.
    BMJ Open. 2022;12:e061893.
    PubMed     Abstract available


  6. FULTON JI, Singh H, Pakkal O, Uleryk EM, et al
    Community-based culturally tailored education programmes for black adults with cardiovascular disease, diabetes, hypertension and stroke: a systematic review protocol of primary empirical studies.
    BMJ Open. 2022;12:e059883.
    PubMed     Abstract available


  7. WAN X, Chau JPC, Wu Y, Xu L, et al
    Effects of a nurse-led peer support intervention for stroke survivors: protocol for a randomised controlled trial.
    BMJ Open. 2022;12:e062531.
    PubMed     Abstract available


  8. ZHANG R, Liu G, Pan Y, Zhou M, et al
    Association between hospital volume, processes of care and outcomes after acute ischaemic stroke: a prospective observational study.
    BMJ Open. 2022;12:e060015.
    PubMed     Abstract available


  9. KILBRIDE C, Warland A, Stewart V, Aweid B, et al
    Rehabilitation using virtual gaming for Hospital and hOMe-Based training for the Upper limb post Stroke (RHOMBUS II): protocol of a feasibility randomised controlled trial.
    BMJ Open. 2022;12:e058905.
    PubMed     Abstract available


  10. MIECH EJ, Perkins AJ, Zhang Y, Myers LJ, et al
    Pairing regression and configurational analysis in health services research: modelling outcomes in an observational cohort using a split-sample design.
    BMJ Open. 2022;12:e061469.
    PubMed     Abstract available


  11. GONZALEZ-PEREZ A, Roberts L, Vora P, Saez ME, et al
    Safety and effectiveness of appropriately and inappropriately dosed rivaroxaban or apixaban versus warfarin in patients with atrial fibrillation: a cohort study with nested case-control analyses from UK primary care.
    BMJ Open. 2022;12:e059311.
    PubMed     Abstract available


    May 2022
  12. PANDE SD, Roy D, Khine AA, Win MM, et al
    Acute kidney injury without need for dialysis, incidence, its impact on long-term stroke survival and progression to chronic kidney disease.
    BMJ Open. 2022;12:e050743.
    PubMed     Abstract available


  13. SUDA S, Nito C, Ihara M, Iguchi Y, et al
    Randomised placebo-controlled multicentre trial to evaluate the efficacy and safety of JTR-161, allogeneic human dental pulp stem cells, in patients with Acute Ischaemic stRoke (J-REPAIR).
    BMJ Open. 2022;12:e054269.
    PubMed     Abstract available



  14. Multicentre collection of uniform data on patients hospitalised for transient ischaemic attack or stroke in the Philippines: the Philippine Neurological Association One Database-Stroke (PNA1DB-Stroke) protocol.
    BMJ Open. 2022;12:e055954.
    PubMed     Abstract available


  15. CHEN HH, Chern YB, Hsu CY, Tang PL, et al
    Kidney transplantation waiting times and risk of cardiovascular events and mortality: a retrospective observational cohort study in Taiwan.
    BMJ Open. 2022;12:e058033.
    PubMed     Abstract available


  16. WU X, Zhang Q, Qiao J, Chen N, et al
    Calligraphy-based rehabilitation exercise for improving the upper limb function of stroke patients: protocol for an evaluator-blinded randomised controlled trial.
    BMJ Open. 2022;12:e052046.
    PubMed     Abstract available


  17. LARSEN BS, Aplin M, Host N, Dominguez H, et al
    Atrial cardiomyopathy in patients with ischaemic stroke: a cross-sectional and prospective cohort study-the COAST study.
    BMJ Open. 2022;12:e061018.
    PubMed     Abstract available


  18. KITE TA, Banning AS, Ladwiniec A, Gale CP, et al
    Very early invasive angiography versus standard of care in higher-risk non-ST elevation myocardial infarction: study protocol for the prospective multicentre randomised controlled RAPID N-STEMI trial.
    BMJ Open. 2022;12:e055878.
    PubMed     Abstract available


  19. WANG L, Ge J, Chen Y, Liu Y, et al
    Predictors for the prognosis and recurrence of ischaemic stroke among young Chinese patients: a cohort study.
    BMJ Open. 2022;12:e052289.
    PubMed     Abstract available


    April 2022
  20. ORTIZ-PRADO E, Cordovez SP, Vasconez E, Viscor G, et al
    Chronic high-altitude exposure and the epidemiology of ischaemic stroke: a systematic review.
    BMJ Open. 2022;12:e051777.
    PubMed     Abstract available


  21. DANESE M, Sidelnikov E, Villa G, Catterick D, et al
    Longitudinal evaluation of treatment patterns, risk factors and outcomes in patients with cardiovascular disease treated with lipid-lowering therapy in the UK.
    BMJ Open. 2022;12:e055015.
    PubMed     Abstract available


  22. HUANG YC, Chang CH, Tsai YH, Weng HH, et al
    PCSK9 inhibition in patients with acute stroke and symptomatic intracranial atherosclerosis: protocol for a prospective, randomised, open-label, blinded end-point trial with vessel-wall MR imaging.
    BMJ Open. 2022;12:e060068.
    PubMed     Abstract available


  23. BIVARD A, Zhao H, Coote S, Campbell B, et al
    Tenecteplase versus Alteplase for Stroke Thrombolysis Evaluation Trial in the Ambulance (Mobile Stroke Unit-TASTE-A): protocol for a prospective randomised, open-label, blinded endpoint, phase II superiority trial of tenecteplase versus alteplase for
    BMJ Open. 2022;12:e056573.
    PubMed     Abstract available


  24. KIM IC, Lee JH, Choi DJ, Park SJ, et al
    Rationale design and efficacy of a smartphone application for improving self-awareness of adherence to edoxaban treatment: study protocol for a randomised controlled trial (adhere app).
    BMJ Open. 2022;12:e048777.
    PubMed     Abstract available


  25. KOKORELIAS KM, Nelson MLA, Cameron JI, Colquhoun H, et al
    Exploring the poststroke experiences and unmet needs of South Asian communities in high-income countries: a scoping review protocol.
    BMJ Open. 2022;12:e059017.
    PubMed     Abstract available


  26. ACKAH M, Salifu MG, Ameyaw L, Boakye H, et al
    Impact of COVID-19 pandemic on acute stroke admissions and case-fatality rate in lower-income and middle-income countries: a protocol for systematic review and meta-analysis.
    BMJ Open. 2022;12:e057893.
    PubMed     Abstract available


  27. MEE H, Clement C, Anwar F, Whiting G, et al
    Exploring the experiences and challenges for patients undergoing cranioplasty: a mixed-methods study protocol.
    BMJ Open. 2022;12:e048072.
    PubMed     Abstract available


  28. YANG HQ, Yin WJ, Liu K, Liu MC, et al
    Renal safety evaluation of aspirin plus edaravone in patients with ischaemic stroke: a retrospective cohort study.
    BMJ Open. 2022;12:e055469.
    PubMed     Abstract available


  29. XU L, Li B, Zhang X, Bai X, et al
    Sex differences in outcomes after mechanical thrombectomy for acute ischemic stroke in the 'real world': protocol for a systematic review and meta-analysis study.
    BMJ Open. 2022;12:e056025.
    PubMed     Abstract available


  30. DAYYANI M, Mousavi Mohammadi E, Ashoorion V, Sadeghirad B, et al
    Aneurysmal subarachnoid haemorrhage-cerebral vasospasm and prophylactic ibuprofen: a randomised controlled pilot trial protocol.
    BMJ Open. 2022;12:e058895.
    PubMed     Abstract available


  31. HAN M, Qin Y, Tong X, Ji L, et al
    Cost-effective analysis of mechanical thrombectomy alone in the treatment of acute ischaemic stroke: a Markov modelling study.
    BMJ Open. 2022;12:e059098.
    PubMed     Abstract available


  32. MAAS WJ, Lahr MMH, Uyttenboogaart M, Buskens E, et al
    Expediting workflow in the acute stroke pathway for endovascular thrombectomy in the northern Netherlands: a simulation model.
    BMJ Open. 2022;12:e056415.
    PubMed     Abstract available


  33. MALLOUK N, Garcin A, Li G, Epinat M, et al
    Platelet transmission electron microscopy for the assessment of poor biological response to antiplatelet agent: pilot descriptive and prospective study - ELECTROSTROKE.
    BMJ Open. 2022;12:e050060.
    PubMed     Abstract available


  34. MILTON AG, Lau S, Kremer KL, Rao SR, et al
    FAST-IT: Find A Simple Test - In TIA (transient ischaemic attack): a prospective cohort study to develop a multivariable prediction model for diagnosis of TIA through proteomic discovery and candidate lipid mass spectrometry, neuroimaging and machine
    BMJ Open. 2022;12:e045908.
    PubMed     Abstract available


  35. GITTINS M, Lugo-Palacios DG, Vail A, Bowen A, et al
    Investigating the association between inpatient stroke therapy and disability, destination on discharge, length of stay and mortality: a prospective cohort study using the Sentinel Stroke National Audit Programme.
    BMJ Open. 2022;12:e059684.
    PubMed     Abstract available


  36. LOREM GF, Opdal IM, Wilsgaard T, Schirmer H, et al
    Assessment of mental health trajectories before and after myocardial infarction, atrial fibrillation or stroke: analysis of a cohort study in Tromso, Norway (Tromso Study, 1994-2016).
    BMJ Open. 2022;12:e052948.
    PubMed     Abstract available


    March 2022
  37. LI G, Li Y, Jing L, Tian Y, et al
    Incremental significance and sex discrepancies of neck circumference on the odds of ischaemic stroke: a multistage, population-based, cross-sectional study from Northeast China.
    BMJ Open. 2022;12:e056932.
    PubMed     Abstract available


  38. ROWE FJ, Hepworth LR, Kirkham JJ
    Development of core outcome sets and core outcome measures for central visual impairment, visual field loss and ocular motility disorders due to stroke: a Delphi and consensus study.
    BMJ Open. 2022;12:e056792.
    PubMed     Abstract available


  39. HOARE S, Powell A, Modi RN, Armstrong N, et al
    Why do people take part in atrial fibrillation screening? Qualitative interview study in English primary care.
    BMJ Open. 2022;12:e051703.
    PubMed     Abstract available


  40. RADFORD KA, McKevitt C, Clarke S, Powers K, et al
    RETurn to work After stroKE (RETAKE) Trial: protocol for a mixed-methods process evaluation using normalisation process theory.
    BMJ Open. 2022;12:e053111.
    PubMed     Abstract available


  41. GAO XF, Ge Z, Kan J, Kong XQ, et al
    Rationale and design for comparison of non-compliant balloon with drug-coating balloon angioplasty for side branch after provisional stenting for patients with true coronary bifurcation lesions: a prospective, multicentre and randomised DCB-BIF trial.
    BMJ Open. 2022;12:e052788.
    PubMed     Abstract available


  42. ESTEVAO C, Baldellou Lopez M, Davis RE, Jarret L, et al
    Evaluation of a community-based performance arts programme for people who have experienced stroke in the UK: protocol for the SHAPER-Stroke Odysseys study.
    BMJ Open. 2022;12:e057805.
    PubMed     Abstract available


  43. LU Y, Xia Y, Wu Y, Pan X, et al
    Repetitive transcranial magnetic stimulation for upper limb motor function and activities of daily living in patients with stroke: a protocol of a systematic review and Bayesian network meta-analysis.
    BMJ Open. 2022;12:e051630.
    PubMed     Abstract available


  44. CHRISTENSEN TD, Bendixen M, Skaarup SH, Jensen JU, et al
    Intrapleural fibrinolysis and DNase versus video-assisted thoracic surgery (VATS) for the treatment of pleural empyema (FIVERVATS): protocol for a randomised, controlled trial - surgery as first-line treatment.
    BMJ Open. 2022;12:e054236.
    PubMed     Abstract available


  45. PARK S, Tang A, Pollock C, Sakakibara BM, et al
    Telerehabilitation for lower extremity recovery poststroke: a systematic review and meta-analysis protocol.
    BMJ Open. 2022;12:e055527.
    PubMed     Abstract available


  46. AL JERDI S, Akhtar N, Mahfoud Z, Kamran S, et al
    Major cardiovascular events in patients presenting with acute stroke: a 5-year follow-up study in patients who had ischaemic stroke and stroke mimics.
    BMJ Open. 2022;12:e053059.
    PubMed     Abstract available


  47. LI H, Huang J, Ye S, Chen H, et al
    Predictors of mortality in acute ischemic stroke treated with endovascular thrombectomy despite successful reperfusion: subgroup analysis of a multicentre randomised clinical trial.
    BMJ Open. 2022;12:e053765.
    PubMed     Abstract available


    February 2022
  48. KILBRIDE C, Scott DJM, Butcher T, Norris M, et al
    Safety, feasibility, acceptability and preliminary effects of the Neurofenix platform for Rehabilitation via HOMe Based gaming exercise for the Upper-limb post Stroke (RHOMBUS): results of a feasibility intervention study.
    BMJ Open. 2022;12:e052555.
    PubMed     Abstract available


  49. HAN M, Baik M, Kim YD, Choi J, et al
    Impact of interankle blood pressure difference on major adverse cardiovascular events in cryptogenic stroke patients without peripheral artery disease: a retrospective cohort study.
    BMJ Open. 2022;12:e054760.
    PubMed     Abstract available


  50. KOHLI-LYNCH CN, Erzse A, Rayner B, Hofman KJ, et al
    Hypertension in the South African public healthcare system: a cost-of-illness and burden of disease study.
    BMJ Open. 2022;12:e055621.
    PubMed     Abstract available


  51. HIMMELREICH JCL, Harskamp RE, Geelhoed B, Virdone S, et al
    Validating risk models versus age alone for atrial fibrillation in a young Dutch population cohort: should atrial fibrillation risk prediction be expanded to younger community members?
    BMJ Open. 2022;12:e057476.
    PubMed     Abstract available


  52. ALABDULAALI L, Hickman L, Punt TD, Jenkinson N, et al
    Effectiveness of transcranial direct current stimulation on hand dexterity in stroke patients: a protocol for a systematic review and meta-analysis.
    BMJ Open. 2022;12:e056064.
    PubMed     Abstract available


  53. ELSHEIKH MA, Moriyama M, Rahman MM, Kako M, et al
    Effect of a tailored multidimensional intervention on the care burden among family caregivers of stroke survivors: a randomised controlled trial.
    BMJ Open. 2022;12:e049741.
    PubMed     Abstract available


  54. RYAN A, Paul CL, Cox M, Whalen O, et al
    TACTICS - Trial of Advanced CT Imaging and Combined Education Support for Drip and Ship: evaluating the effectiveness of an 'implementation intervention' in providing better patient access to reperfusion therapies: protocol for a non-randomised contro
    BMJ Open. 2022;12:e055461.
    PubMed     Abstract available


  55. CALLANAN A, Quinlan D, O'Sullivan S, Bradley CP, et al
    Atrial fibrillation (AF) pilot screening programme in primary care in Ireland: an implementation study protocol.
    BMJ Open. 2022;12:e054324.
    PubMed     Abstract available


    January 2022
  56. LIU Y, Liu Z, Peng R, Xiao R, et al
    Preoperative stereotactic body radiotherapy combined with surgical treatment for renal cell carcinoma and inferior vena cava tumour thrombus: study protocol for a single-arm cohort trial.
    BMJ Open. 2022;12:e055364.
    PubMed     Abstract available


  57. TAMRAT EG, Gufue ZH, Getachew S, Yifru YM, et al
    Factors associated with the longer-term unmet supportive care needs of stroke survivors in Ethiopia: a multicentre cross-sectional study.
    BMJ Open. 2022;12:e053579.
    PubMed     Abstract available


  58. EVANS NR, Sibson L, Day DJ, Agarwal S, et al
    Hyperacute stroke thrombolysis via telemedicine: a multicentre study of performance, safety and clinical efficacy.
    BMJ Open. 2022;12:e057372.
    PubMed     Abstract available


  59. DUAN YJ, Hua XY, Zheng MX, Wu JJ, et al
    Corticocortical paired associative stimulation for treating motor dysfunction after stroke: study protocol for a randomised sham-controlled double-blind clinical trial.
    BMJ Open. 2022;12:e053991.
    PubMed     Abstract available


  60. FOX KAA, Virdone S, Bassand JP, Camm AJ, et al
    Do baseline characteristics and treatments account for geographical disparities in the outcomes of patients with newly diagnosed atrial fibrillation? The prospective GARFIELD-AF registry.
    BMJ Open. 2022;12:e049933.
    PubMed     Abstract available


  61. MAHMOOD A, Deshmukh A, Natarajan M, Marsden D, et al
    Development of strategies to support home-based exercise adherence after stroke: a Delphi consensus.
    BMJ Open. 2022;12:e055946.
    PubMed     Abstract available


  62. WANNER M, Schonherr G, Kiechl S, Knoflach M, et al
    Feasibility of an individualised, task-oriented, video-supported home exercise programme for arm function in patients in the subacute phase after stroke: protocol of a randomised controlled pilot study.
    BMJ Open. 2022;12:e051504.
    PubMed     Abstract available


    December 2021
  63. CHOO E, Choi E, Lee J, Siachalinga L, et al
    Assessment of the effects of methodological choice in continuity of care research: a real-world example with dyslipidaemia cohort.
    BMJ Open. 2021;11:e053140.
    PubMed     Abstract available


  64. FLINK M, Lindblom S, Tistad M, Laska AC, et al
    Person-centred care transitions for people with stroke: study protocol for a feasibility evaluation of codesigned care transition support.
    BMJ Open. 2021;11:e047329.
    PubMed     Abstract available


  65. FUGEMANN H, Goerling U, Godde K, Desch AK, et al
    What do people with lung cancer and stroke expect from patient navigation? A qualitative study in Germany.
    BMJ Open. 2021;11:e050601.
    PubMed     Abstract available


  66. ZHANG Y, Wang S, Cheng Q, Zhang J, et al
    Reperfusion strategy and in-hospital outcomes for ST elevation myocardial infarction in secondary and tertiary hospitals in predominantly rural central China: a multicentre, prospective and observational study.
    BMJ Open. 2021;11:e053510.
    PubMed     Abstract available


  67. BULSARA C, Saunders R, Emery L, Etherton-Beer C, et al
    Reflecting on experiences of care: an exploratory qualitative descriptive study of the perspectives of stroke survivors, families and staff.
    BMJ Open. 2021;11:e047559.
    PubMed     Abstract available


  68. NASREEN S, Calzavara AJ, Sundaram ME, MacDonald SE, et al
    Background incidence rates of hospitalisations and emergency department visits for thromboembolic and coagulation disorders in Ontario, Canada for COVID-19 vaccine safety assessment: a population-based retrospective observational study.
    BMJ Open. 2021;11:e052019.
    PubMed     Abstract available


  69. NGUYEN HT, Nguyen HVB, Nguyen HQ, Le HQ, et al
    Prevalence of left atrial appendage thrombus in patients with acute ischaemic stroke and sinus rhythm: a cross-sectional study.
    BMJ Open. 2021;11:e051563.
    PubMed     Abstract available


  70. SIMUNOVIC MP, Shao EH, Osaadon P, Sasongko MB, et al
    Two-step versus 1-step subretinal injection to compare subretinal drug delivery: a randomised study protocol.
    BMJ Open. 2021;11:e049976.
    PubMed     Abstract available


  71. YOU Y, Niu Y, Sun F, Zhang J, et al
    Impact of COVID-19 pandemic on haemorrhagic stroke admissions: a systematic review and meta-analysis.
    BMJ Open. 2021;11:e050559.
    PubMed     Abstract available


  72. LIU J, Lei Y, Liao J, Liang X, et al
    Study protocol: haemostatic efficacy and safety of preemptive antifibrinolysis with multidose intravenous tranexamic acid in elderly hip fracture patients: design of a prospective randomised controlled trial.
    BMJ Open. 2021;11:e047382.
    PubMed     Abstract available


  73. CAO M, Guan T, Han X, Shen B, et al
    Impact of a health campaign on Chinese public awareness of stroke: evidence from internet search data.
    BMJ Open. 2021;11:e054463.
    PubMed     Abstract available


  74. PILLING LC, Turkmen D, Fullalove H, Atkins JL, et al
    Analysis of CYP2C19 genetic variants with ischaemic events in UK patients prescribed clopidogrel in primary care: a retrospective cohort study.
    BMJ Open. 2021;11:e053905.
    PubMed     Abstract available


  75. ESKILDSEN SJ, Poulsen I, Jakobsen D, Riberholt CG, et al
    Scoping review to identify and map non-pharmacological, non-surgical treatments for dysphagia following moderate-to-severe acquired brain injury.
    BMJ Open. 2021;11:e053244.
    PubMed     Abstract available


  76. FISHER RJ, Riley-Bennett F, Russell L, Lee C, et al
    Nominal group technique to establish the core components of home-based rehabilitation for survivors of stroke with severe disability.
    BMJ Open. 2021;11:e052593.
    PubMed     Abstract available


  77. HICKSON RP, Kucharska-Newton AM, Rodgers JE, Sleath BL, et al
    Disparities by sex in P2Y12 inhibitor therapy duration, or differences in the balance of ischaemic-benefit and bleeding-risk clinical outcomes in older women versus comparable men following acute myocardial infarction? A P2Y12 inhibitor new user retro
    BMJ Open. 2021;11:e050236.
    PubMed     Abstract available


    November 2021
  78. LIU Y, Li J, Dou Y, Ma H, et al
    Impacts of type 2 diabetes mellitus and hypertension on the incidence of cardiovascular diseases and stroke in China real-world setting: a retrospective cohort study.
    BMJ Open. 2021;11:e053698.
    PubMed     Abstract available


  79. HUANG YC, Lee JD, Weng HH, Lin LC, et al
    Statin and dual antiplatelet therapy for the prevention of early neurological deterioration and recurrent stroke in branch atheromatous disease: a protocol for a prospective single-arm study using a historical control for comparison.
    BMJ Open. 2021;11:e054381.
    PubMed     Abstract available


  80. VAN NIEKERK SM, Kamalakannan S, Inglis-Jassiem G, Charumbira MY, et al
    Towards universal health coverage for people with stroke in South Africa: a scoping review.
    BMJ Open. 2021;11:e049988.
    PubMed     Abstract available


  81. HUGUES A, Guinet-Lacoste A, Bin S, Villeneuve L, et al
    Effects of prismatic adaptation on balance and postural disorders in patients with chronic right stroke: protocol for a multicentre double-blind randomised sham-controlled trial.
    BMJ Open. 2021;11:e052086.
    PubMed     Abstract available


  82. VIKTORISSON A, Buvarp D, Sunnerhagen KS
    Prestroke physical activity and outcomes after intracerebral haemorrhage in comparison to ischaemic stroke: protocol for a matched cohort study (part of PAPSIGOT).
    BMJ Open. 2021;11:e053067.
    PubMed     Abstract available


  83. ANEMAAT L, Palmer VJ, Copland DA, Mainstone K, et al
    Using experience-based codesign to coproduce aphasia rehabilitation services: study protocol.
    BMJ Open. 2021;11:e047398.
    PubMed     Abstract available


  84. QIN H, Turnbull I, Chen Y, Wright N, et al
    Hospital management of major stroke types in Chinese adults: a population-based study of 20 000 hospitalised stroke cases.
    BMJ Open. 2021;11:e054265.
    PubMed     Abstract available


  85. WIBERG S, Kjaergaard J, Mogelvang R, Moller CH, et al
    Efficacy of a glucagon-like peptide-1 agonist and restrictive versus liberal oxygen supply in patients undergoing coronary artery bypass grafting or aortic valve replacement: study protocol for a 2-by-2 factorial designed, randomised clinical trial.
    BMJ Open. 2021;11:e052340.
    PubMed     Abstract available


  86. VYAS MV, Fang J, Austin PC, Laupacis A, et al
    Importance of accounting for loss to follow-up when comparing mortality between immigrants and long-term residents: a population-based retrospective cohort.
    BMJ Open. 2021;11:e046377.
    PubMed     Abstract available


  87. NADARAJAH R, Wu J, Frangi AF, Hogg D, et al
    Predicting patient-level new-onset atrial fibrillation from population-based nationwide electronic health records: protocol of FIND-AF for developing a precision medicine prediction model using artificial intelligence.
    BMJ Open. 2021;11:e052887.
    PubMed     Abstract available


    October 2021
  88. HOWELL S, Stivland TM, Stein K, Ellenbogen K, et al
    Response to cardiac resynchronisation therapy in men and women: a secondary analysis of the SMART-AV randomised controlled trial.
    BMJ Open. 2021;11:e049017.
    PubMed     Abstract available


  89. MKOMA GF, Johnsen SP, Iversen HK, Andersen G, et al
    Incidence of stroke, transient ischaemic attack and determinants of poststroke mortality among immigrants in Denmark, 20042018: a population-based cohort study.
    BMJ Open. 2021;11:e049347.
    PubMed     Abstract available


  90. VAHLBERG BM, Lundstrom E, Eriksson S, Holmback U, et al
    Potential effects on cardiometabolic risk factors and body composition by short message service (SMS)-guided training after recent minor stroke or transient ischaemic attack: post hoc analyses of the STROKEWALK randomised controlled trial.
    BMJ Open. 2021;11:e054851.
    PubMed     Abstract available


  91. SARTOR MM, Grau-Sanchez J, Guillen-Sola A, Boza R, et al
    Intensive rehabilitation programme for patients with subacute stroke in an inpatient rehabilitation facility: describing a protocol of a prospective cohort study.
    BMJ Open. 2021;11:e046346.
    PubMed     Abstract available


  92. PHROMMINTIKUL A, Nathisuwan S, Gunaparn S, Krittayaphong R, et al
    Prospective randomised trial examining the impact of an educational intervention versus usual care on anticoagulation therapy control based on an SAMe-TT2R2 score-guided strategy in anticoagulant-naive Thai patients with atrial fibrillation (TREATS-AF
    BMJ Open. 2021;11:e051987.
    PubMed     Abstract available


  93. TORLINSKA B, Hazlehurst JM, Nirantharakumar K, Thomas GN, et al
    wEight chanGes, caRdio-mEtabolic risks and morTality in patients with hyperthyroidism (EGRET): a protocol for a CPRD-HES linked cohort study.
    BMJ Open. 2021;11:e055219.
    PubMed     Abstract available


    September 2021
  94. WANG X, Wang X, Yu Y, Han R, et al
    Continuation versus discontinuation of aspirin-based antiplatelet therapy for perioperative bleeding and ischaemic events in adults undergoing neurosurgery: protocol for a systematic review and meta-analysis.
    BMJ Open. 2021;11:e046741.
    PubMed     Abstract available


  95. PENGPID S, Peltzer K
    Prevalence and associated factors of self-reported ischaemic heart disease and/or stroke: a cross-sectional nationally representative community-based study of adults in Malawi in 2017.
    BMJ Open. 2021;11:e048167.
    PubMed     Abstract available


  96. OSEI E, Zandbergen A, Brouwers PJAM, Mulder LJMM, et al
    Safety, feasibility and efficacy of metformin and sitagliptin in patients with a TIA or minor ischaemic stroke and impaired glucose tolerance.
    BMJ Open. 2021;11:e046113.
    PubMed     Abstract available


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