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The Medical Article of the Year 2008:
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78.
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Articles published in J Biol Chem

Retrieve available abstracts of 48 articles:
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Single Articles


    June 2008
  1. XU D , Dwyer J, Li H, Duan W, et al
    Ets2 maintains hTERT gene expression and breast cancer cell proliferation by interacting with c-myc.
    J Biol Chem. 2008;.
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    May 2008
  2. CHEN Y , Shi L, Zhang L, Li R, et al
    The molecular mechanism governing the oncogenic potential of sox2 in breast cancer.
    J Biol Chem. 2008;.
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    March 2008
  3. HU P , Kinyamu HK, Wang L, Martin J, et al
    Estrogen induces estrogen-related receptor alpha gene expression and chromatin structural changes in estrogen receptor (ER)-positive and ER-negative breast cancer cells.
    J Biol Chem. 2008;283:6752-63.
    PubMed     Related articles    Abstract available


  4. PAN MR , Hou MF, Chang HC, Hung WC, et al
    Cyclooxygenase-2 up-regulates CCR7 via EP2/EP4 receptor signaling pathways to enhance lymphatic invasion of breast cancer cells.
    J Biol Chem. 2008;.
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    February 2008
  5. KRAUT-COHEN J , Muller WJ, Elson A
    Protein-tyrosine phosphatase epsilon regulates Shc signaling in a kinase-specific manner: increasing coherence in tyrosine phosphatase signaling.
    J Biol Chem. 2008;283:4612-21.
    PubMed     Related articles    Abstract available


    January 2008
  6. SIDERA K , Gaitanou M, Stellas D, Matsas R, et al
    A critical role for HSP90 in cancer cell invasion involves interaction with the extracellular domain of HER-2.
    J Biol Chem. 2008;283:2031-41.
    PubMed     Related articles    Abstract available


  7. ABRAHAMS A , Mowla S, Parker MI, Goding CR, et al
    UV-mediated regulation of the anti-senescence factor Tbx2.
    J Biol Chem. 2008;283:2223-30.
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  8. HURST DR , Xie Y, Vaidya KS, Mehta A, et al
    Alterations of breast cancer metastasis suppressor 1:At rich interactive domain 4A interaction modify gene expression but still suppress metastasis in human breast cancer cells.
    J Biol Chem. 2008;.
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  9. JADESKI L , Mataraza JM, Jeong HW, Li Z, et al
    IQGAP1 stimulates proliferation and enhances tumorigenesis of human breast epithelial cells.
    J Biol Chem. 2008;283:1008-17.
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  10. HUANG L , Cheng HC, Isom R, Chen CS, et al
    PKCepsilon mediates polymeric fibronectin assembly on the surface of blood-borne rat breast cancer cells to promote pulmonary metastasis.
    J Biol Chem. 2008;.
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    December 2007
  11. THANGASAMY A , Rogge J, Ammanamanchi S
    Regulation of RON tyrosine kinase mediated invasion of breast cancer cells.
    J Biol Chem. 2007;.
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  12. SUBBARAMAIAH K , Hudis C, Chang SH, Hla T, et al
    EP2 and EP4 receptors regulate aromatase expression in human adipocytes and breast cancer cells. Evidence of a BRCA1 and p300 exchange.
    J Biol Chem. 2007;.
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  13. SADIKOVIC B , Andrews J, Carter D, Robinson J, et al
    Genome-wide H3K9 histone acetylation profiles are altered in benzopyrene treated MCF7 breast cancer cells.
    J Biol Chem. 2007;.
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  14. MA J , Yan R, Zu X, Cheng JM, et al
    Aldo-keto reductase family 1 B10 affects fatty acid synthesis by regulating the stability of acetyl-coa carboxylase-alpha in breast cancer cells.
    J Biol Chem. 2007;.
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    November 2007
  15. EVANS PM , Zhang W, Chen X, Yang J, et al
    Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation.
    J Biol Chem. 2007;282:33994-4002.
    PubMed     Related articles    Abstract available


  16. GOULET I , Gauvin G, Boisvenue S, Cote J, et al
    Alternative splicing yields protein arginine methyltransferase 1 isoforms with distinct activity, substrate specificity, and subcellular localization.
    J Biol Chem. 2007;282:33009-21.
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  17. FRANKEL LB , Christoffersen NR, Jacobsen A, Lindow M, et al
    Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells.
    J Biol Chem. 2007;.
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    October 2007
  18. CHANDRA D , Choy G, Tang DG
    Cytosolic accumulation of HSP60 during apoptosis with or without apparent mitochondrial release: evidence that its pro-apoptotic or pro-survival functions involve differential interactions with caspase-3.
    J Biol Chem. 2007;282:31289-301.
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  19. QI X , Pohl NM, Loesch M, Hou S, et al
    p38alpha antagonizes p38gamma activity through c-Jun-dependent ubiquitin-proteasome pathways in regulating Ras transformation and stress response.
    J Biol Chem. 2007;282:31398-408.
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  20. MONTALBANO J , Jin W, Sheikh MS, Huang Y, et al
    RBEL1 is a novel gene that encodes a nucleo-cytoplasmic Ras superfamily GTP-binding protein and is overexpressed in breast cancer.
    J Biol Chem. 2007;.
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  21. ECKSTEIN N , Servan K, Girard L, Cai D, et al
    EGFR-pathway analysis identifies amphiregulin as a key factor for cisplatin resistance of human breast cancer cells.
    J Biol Chem. 2007;.
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  22. KOJIC LD , Joshi B, Lajoie P, Le PU, et al
    Raft-dependent endocytosis of autocrine motility factor is phosphatidylinositol 3-kinase-dependent in breast carcinoma cells.
    J Biol Chem. 2007;282:29305-13.
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    September 2007
  23. LANVIN O , Bianco S, Kersual N, Chalbos D, et al
    Potentiation of ICI182,780 (Fulvestrant)-induced estrogen receptor-alpha degradation by the estrogen receptor-related receptor-alpha inverse agonist XCT790.
    J Biol Chem. 2007;282:28328-34.
    PubMed     Related articles    Abstract available


    August 2007
  24. WOO SY , Kim DH, Jun CB, Kim YM, et al
    PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.
    J Biol Chem. 2007;282:25604-12.
    PubMed     Related articles    Abstract available


  25. FERNANDO R , Foster JS, Bible A, Strom A, et al
    Breast cancer cell proliferation is inhibited by bad: Regulation of cyclin D1.
    J Biol Chem. 2007;.
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    July 2007
  26. GUO HB , Randolph M, Pierce M
    Inhibition of a specific N-glycosylation activity results in attenuation of breast carcinoma cell invasiveness-related phenotypes: inhibition of epidermal growth factor-induced dephosphorylation of focal adhesion kinase.
    J Biol Chem. 2007;282:22150-62.
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  27. KEBACHE S , Ash J, Annis MG, Hagan J, et al
    Grb10 and active Raf-1 kinase promote Bad-dependent cell survival.
    J Biol Chem. 2007;282:21873-83.
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  28. BASU I , Cordovano G, Das I, Belbin TJ, et al
    A transition state analogue of 5'-methylthioadenosine phosphorylase induces apoptosis in head and neck cancers.
    J Biol Chem. 2007;282:21477-86.
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  29. MAZUREK N , Sun YJ, Liu KF, Gilcrease MZ, et al
    Phosphorylated galectin-3 mediates tumor necrosis factor-related apoptosis-inducing ligand signaling by regulating phosphatase and tensin homologue deleted on chromosome 10 in human breast carcinoma cells.
    J Biol Chem. 2007;282:21337-48.
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  30. YOON S , Lee MY, Park SW, Moon JS, et al
    Upregulation of acetyl-CoA carboxylase alpha and fatty acid synthase by HER2 at translational level in breast cancer cells.
    J Biol Chem. 2007;.
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  31. TEMBE V , Henderson BR
    BARD1 translocation to mitochondria correlates with Bax oligomerization, loss of mitochondrial membrane potential, and apoptosis.
    J Biol Chem. 2007;282:20513-22.
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  32. SU JL , Yang CY, Zhao M, Kuo ML, et al
    Forkhead proteins are critical for bone morphogenetic protein-2 regulation and anti-tumor activity of resveratrol.
    J Biol Chem. 2007;282:19385-98.
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    May 2007
  33. SLACK-DAVIS JK , Martin KH, Tilghman RW, Iwanicki M, et al
    Cellular characterization of a novel focal adhesion kinase inhibitor.
    J Biol Chem. 2007;282:14845-52.
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  34. LEE SA , Jung M
    The nucleoside analog sangivamycin induces apoptotic cell death in breast carcinoma MCF7/adriamycin-resistant cells via protein kinase Cdelta and JNK activation.
    J Biol Chem. 2007;282:15271-83.
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  35. ZHU S , Si ML, Wu H, Mo YY, et al
    MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1).
    J Biol Chem. 2007;282:14328-36.
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  36. SASAKI M , Nie L, Maki CG
    MDM2 binding induces a conformational change in p53 that is opposed by heat-shock protein 90 and precedes p53 proteasomal degradation.
    J Biol Chem. 2007;282:14626-34.
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  37. SASTRY KS , Karpova Y, Prokopovich S, Smith AJ, et al
    Epinephrine protects cancer cells from apoptosis via activation of cAMP-dependent protein kinase and BAD phosphorylation.
    J Biol Chem. 2007;282:14094-100.
    PubMed     Related articles    Abstract available


  38. SPICHAL L , Krystof V, Paprskarova M, Lenobel R, et al
    Classical anticytokinins do not interact with cytokinin receptors but inhibit cyclin-dependent kinases.
    J Biol Chem. 2007;282:14356-63.
    PubMed     Related articles    Abstract available


  39. YANG Y , Macleod V, Miao HQ, Theus A, et al
    Heparanase enhances syndecan-1 shedding: a novel mechanism for stimulation of tumor growth and metastasis.
    J Biol Chem. 2007;282:13326-33.
    PubMed     Related articles    Abstract available


    April 2007
  40. HITOSUGI T , Sasaki K, Sato M, Suzuki Y, et al
    Epidermal growth factor directs sex-specific steroid signaling through Src activation.
    J Biol Chem. 2007;282:10697-706.
    PubMed     Related articles    Abstract available


  41. HSU SC , Hung MC
    Characterization of a novel tripartite nuclear localization sequence in the EGFR family.
    J Biol Chem. 2007;282:10432-40.
    PubMed     Related articles    Abstract available


    March 2007
  42. HAMILTON SR , Fard SF, Paiwand FF, Tolg C, et al
    The hyaluronan receptors CD44 and RHAMM (CD168) form complexes with ERK1,2, which sustain high basal motility in breast cancer cells.
    J Biol Chem. 2007;.
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  43. SANTIAGO-JOSEFAT B , Esselens C, Bech-Serra JJ, Arribas J, et al
    Post-transcriptional up-regulation of ADAM17 upon epidermal growth factor receptor activation and in breast tumors.
    J Biol Chem. 2007;282:8325-31.
    PubMed     Related articles    Abstract available


  44. NARITA K , Chien J, Mullany SA, Staub J, et al
    Loss of Hsulf-1 expression enhances autocrine signaling mediated by amphiregulin in breast cancer.
    J Biol Chem. 2007;.
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    February 2007
  45. SHAJAHAN AN , Wang A, Decker M, Minshall RD, et al
    Caveolin-1 tyrosine phosphorylation enhances paclitaxel-mediated cytotoxicity.
    J Biol Chem. 2007;282:5934-43.
    PubMed     Related articles    Abstract available


  46. LI H , Wang X, Li N, Qiu J, et al
    hPEBP4 resists TRAIL-induced apoptosis of human prostate cancer cells by activating Akt and deactivating ERK1/2 pathways.
    J Biol Chem. 2007;282:4943-50.
    PubMed     Related articles    Abstract available


  47. HEWITSON KS , Lienard BM, McDonough MA, Clifton IJ, et al
    Structural and mechanistic studies on the inhibition of the hypoxia-inducible transcription factor hydroxylases by tricarboxylic acid cycle intermediates.
    J Biol Chem. 2007;282:3293-301.
    PubMed     Related articles    Abstract available


  48. POLGAR N , Fogelgren B, Shipley JM, Csiszar K, et al
    Lysyl oxidase interacts with hormone placental lactogen and synergistically promotes breast epithelial cell proliferation and migration.
    J Biol Chem. 2007;282:3262-72.
    PubMed     Related articles    Abstract available


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