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The Medical Article of the Year 2008:
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78.
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Articles published in Oncogene

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Single Articles


    June 2008
  1. UEKI T , Nishidate T, Park JH, Lin ML, et al
    Involvement of elevated expression of multiple cell-cycle regulator, DTL/RAMP (denticleless/RA-regulated nuclear matrix associated protein), in the growth of breast cancer cells.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


    May 2008
  2. TSCHAN MP , Reddy VA, Ress A, Arvidsson G, et al
    PU.1 binding to the p53 family of tumor suppressors impairs their transcriptional activity.
    Oncogene. 2008;27:3489-93.
    PubMed     Related articles    Abstract available


  3. BHAUMIK D , Scott GK, Schokrpur S, Patil CK, et al
    Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


  4. SZABOVA L , Chrysovergis K, Yamada SS, Holmbeck K, et al
    MT1-MMP is required for efficient tumor dissemination in experimental metastatic disease.
    Oncogene. 2008;27:3274-81.
    PubMed     Related articles    Abstract available


  5. FRECH MS , Torre KM, Robinson GW, Furth PA, et al
    Loss of cyclin D1 in concert with deregulated estrogen receptor alpha expression induces DNA damage response activation and interrupts mammary gland morphogenesis.
    Oncogene. 2008;27:3186-93.
    PubMed     Related articles    Abstract available


  6. OSIPO C , Patel P, Rizzo P, Clementz AG, et al
    ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


  7. CAFFAREL MM , Moreno-Bueno G, Cerutti C, Palacios J, et al
    JunD is involved in the antiproliferative effect of Delta(9)-tetrahydrocannabinol on human breast cancer cells.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


    April 2008
  8. SHAFIEI F , Rahnama F, Pawella L, Mitchell MD, et al
    DNMT3A and DNMT3B mediate autocrine hGH repression of plakoglobin gene transcription and consequent phenotypic conversion of mammary carcinoma cells.
    Oncogene. 2008;27:2602-12.
    PubMed     Related articles    Abstract available


  9. YU JS , Koujak S, Nagase S, Li CM, et al
    PCDH8, the human homolog of PAPC, is a candidate tumor suppressor of breast cancer.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


  10. SAVIO MG , Rotondo G, Maglie S, Rossetti G, et al
    COP1D, an alternatively spliced constitutive photomorphogenic-1 (COP1) product, stabilizes UV stress-induced c-Jun through inhibition of full-length COP1.
    Oncogene. 2008;27:2401-11.
    PubMed     Related articles    Abstract available


  11. YIN X , Dewille JW, Hai T
    A potential dichotomous role of ATF3, an adaptive-response gene, in cancer development.
    Oncogene. 2008;27:2118-27.
    PubMed     Related articles    Abstract available


  12. MOROZOV VM , Massoll NA, Vladimirova OV, Maul GG, et al
    Regulation of c-met expression by transcription repressor Daxx.
    Oncogene. 2008;27:2177-86.
    PubMed     Related articles    Abstract available


    March 2008
  13. KHALEQUE MA , Bharti A, Gong J, Gray PJ, et al
    Heat shock factor 1 represses estrogen-dependent transcription through association with MTA1.
    Oncogene. 2008;27:1886-93.
    PubMed     Related articles    Abstract available


  14. GARZIA L , D'Angelo A, Amoresano A, Knauer SK, et al
    Phosphorylation of nm23-H1 by CKI induces its complex formation with h-prune and promotes cell motility.
    Oncogene. 2008;27:1853-64.
    PubMed     Related articles    Abstract available


  15. EELEN G , Vanden Bempt I, Verlinden L, Drijkoningen M, et al
    Expression of the BRCA1-interacting protein Brip1/BACH1/FANCJ is driven by E2F and correlates with human breast cancer malignancy.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


  16. STEELMAN LS , Navolanic PM, Sokolosky ML, Taylor JR, et al
    Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


  17. PHILLIPS A , Blaydes JP
    MNK1 and EIF4E are downstream effectors of MEKs in the regulation of the nuclear export of HDM2 mRNA.
    Oncogene. 2008;27:1645-9.
    PubMed     Related articles    Abstract available


  18. FLEURY L , Gerus M, Lavigne AC, Richard-Foy H, et al
    Eliminating epigenetic barriers induces transient hormone-regulated gene expression in estrogen receptor negative breast cancer cells.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


    February 2008
  19. WENDT MK , Cooper AN, Dwinell MB
    Epigenetic silencing of CXCL12 increases the metastatic potential of mammary carcinoma cells.
    Oncogene. 2008;27:1461-71.
    PubMed     Related articles    Abstract available


  20. SAUERMANN M , Sahin O, Sultmann H, Hahne F, et al
    Reduced expression of vacuole membrane protein 1 affects the invasion capacity of tumor cells.
    Oncogene. 2008;27:1320-6.
    PubMed     Related articles    Abstract available


  21. AVEROUS J , Fonseca BD, Proud CG
    Regulation of cyclin D1 expression by mTORC1 signaling requires eukaryotic initiation factor 4E-binding protein 1.
    Oncogene. 2008;27:1106-13.
    PubMed     Related articles    Abstract available


  22. GADIR N , Jackson DN, Lee E, Foster DA, et al
    Defective TGF-beta signaling sensitizes human cancer cells to rapamycin.
    Oncogene. 2008;27:1055-62.
    PubMed     Related articles    Abstract available


  23. RAYTER S , Elliott R, Travers J, Rowlands MG, et al
    A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D.
    Oncogene. 2008;27:1036-44.
    PubMed     Related articles    Abstract available


  24. D'ASSORO AB , Busby R, Acu ID, Quatraro C, et al
    Impaired p53 function leads to centrosome amplification, acquired ERalpha phenotypic heterogeneity and distant metastases in breast cancer MCF-7 xenografts.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


  25. BOTLAGUNTA M , Vesuna F, Mironchik Y, Raman A, et al
    Oncogenic role of DDX3 in breast cancer biogenesis.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


    January 2008
  26. OXMANN D , Held-Feindt J, Stark AM, Hattermann K, et al
    Endoglin expression in metastatic breast cancer cells enhances their invasive phenotype.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


  27. HAYES NV , Newsam RJ, Baines AJ, Gullick WJ, et al
    Characterization of the cell membrane-associated products of the Neuregulin 4 gene.
    Oncogene. 2008;27:715-20.
    PubMed     Related articles    Abstract available


  28. CHANG TW , Chen CC, Chen KY, Su JH, et al
    Ribosomal phosphoprotein P0 interacts with GCIP and overexpression of P0 is associated with cellular proliferation in breast and liver carcinoma cells.
    Oncogene. 2008;27:332-8.
    PubMed     Related articles    Abstract available


    December 2007
  29. HOWARTH KD , Blood KA, Ng BL, Beavis JC, et al
    Array painting reveals a high frequency of balanced translocations in breast cancer cell lines that break in cancer-relevant genes.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  30. LIEN HC , Hsiao YH, Lin YS, Yao YT, et al
    Molecular signatures of metaplastic carcinoma of the breast by large-scale transcriptional profiling: identification of genes potentially related to epithelial-mesenchymal transition.
    Oncogene. 2007;26:7859-71.
    PubMed     Related articles    Abstract available


  31. GERY S , Virk RK, Chumakov K, Yu A, et al
    The clock gene Per2 links the circadian system to the estrogen receptor.
    Oncogene. 2007;26:7916-20.
    PubMed     Related articles    Abstract available


  32. MELCHOR L , Honrado E, Garcia MJ, Alvarez S, et al
    Distinct genomic aberration patterns are found in familial breast cancer associated with different immunohistochemical subtypes.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  33. AL-AZAWI D , Ilroy MM, Kelly G, Redmond AM, et al
    Ets-2 and p160 proteins collaborate to regulate c-Myc in endocrine resistant breast cancer.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


    November 2007
  34. GUDMUNDSDOTTIR K , Lord CJ, Ashworth A
    The proteasome is involved in determining differential utilization of double-strand break repair pathways.
    Oncogene. 2007;26:7601-6.
    PubMed     Related articles    Abstract available


  35. BRUTON RK , Rasti M, Mapp KL, Young N, et al
    C-terminal-binding protein interacting protein binds directly to adenovirus early region 1A through its N-terminal region and conserved region 3.
    Oncogene. 2007;26:7467-79.
    PubMed     Related articles    Abstract available


  36. TOMMISKA J , Bartkova J, Heinonen M, Hautala L, et al
    The DNA damage signalling kinase ATM is aberrantly reduced or lost in BRCA1/BRCA2-deficient and ER/PR/ERBB2-triple-negative breast cancer.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


    October 2007
  37. GLAROS S , Cirrincione GM, Muchardt C, Kleer CG, et al
    The reversible epigenetic silencing of BRM: implications for clinical targeted therapy.
    Oncogene. 2007;26:7058-66.
    PubMed     Related articles    Abstract available


  38. AIGNER K , Dampier B, Descovich L, Mikula M, et al
    The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity.
    Oncogene. 2007;26:6979-88.
    PubMed     Related articles    Abstract available


  39. VECCHI M , Confalonieri S, Nuciforo P, Vigano MA, et al
    Breast cancer metastases are molecularly distinct from their primary tumors.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  40. MIGLIACCIO A , Varricchio L, De Falco A, Castoria G, et al
    Inhibition of the SH3 domain-mediated binding of Src to the androgen receptor and its effect on tumor growth.
    Oncogene. 2007;26:6619-29.
    PubMed     Related articles    Abstract available


  41. WU J , Jin YJ, Calaf GM, Huang WL, et al
    PAC1 is a direct transcription target of E2F-1 in apoptotic signaling.
    Oncogene. 2007;26:6526-35.
    PubMed     Related articles    Abstract available


    September 2007
  42. WANG N , Lin KK, Lu Z, Lam KS, et al
    The LIM-only factor LMO4 regulates expression of the BMP7 gene through an HDAC2-dependent mechanism, and controls cell proliferation and apoptosis of mammary epithelial cells.
    Oncogene. 2007;26:6431-41.
    PubMed     Related articles    Abstract available


  43. MILLIKEN EL , Lozada KL, Johnson E, Landis MD, et al
    Ovarian hyperstimulation induces centrosome amplification and aneuploid mammary tumors independently of alterations in p53 in a transgenic mouse model of breast cancer.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  44. COOPER WN , Dickinson RE, Dallol A, Grigorieva EV, et al
    Epigenetic regulation of the ras effector/tumour suppressor RASSF2 in breast and lung cancer.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  45. LI Y , Huang J, Zhao YL, He J, et al
    UTRN on chromosome 6q24 is mutated in multiple tumors.
    Oncogene. 2007;26:6220-8.
    PubMed     Related articles    Abstract available


  46. ZISMAN-ROZEN S , Fink D, Ben-Izhak O, Fuchs Y, et al
    Downregulation of Sef, an inhibitor of receptor tyrosine kinase signaling, is common to a variety of human carcinomas.
    Oncogene. 2007;26:6093-8.
    PubMed     Related articles    Abstract available


  47. YULI C , Shao N, Rao R, Aysola P, et al
    BRCA1a has antitumor activity in TN breast, ovarian and prostate cancers.
    Oncogene. 2007;26:6031-7.
    PubMed     Related articles    Abstract available


  48. SEKINE Y , Ikeda O, Hayakawa Y, Tsuji S, et al
    DUSP22/LMW-DSP2 regulates estrogen receptor-alpha-mediated signaling through dephosphorylation of Ser-118.
    Oncogene. 2007;26:6038-49.
    PubMed     Related articles    Abstract available


  49. LAGADEC C , Adriaenssens E, Toillon RA, Chopin V, et al
    Tamoxifen and TRAIL synergistically induce apoptosis in breast cancer cells.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


    August 2007
  50. OH KB , Stanton MJ, West WW, Todd GL, et al
    Tsg101 is upregulated in a subset of invasive human breast cancers and its targeted overexpression in transgenic mice reveals weak oncogenic properties for mammary cancer initiation.
    Oncogene. 2007;26:5950-9.
    PubMed     Related articles    Abstract available


  51. WILLIAMS C , Edvardsson K, Lewandowski SA, Strom A, et al
    A genome-wide study of the repressive effects of estrogen receptor beta on estrogen receptor alpha signaling in breast cancer cells.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  52. SRINIVASAN D , Sims JT, Plattner R
    Aggressive breast cancer cells are dependent on activated Abl kinases for proliferation, anchorage-independent growth and survival.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  53. LUE H , Thiele M, Franz J, Dahl E, et al
    Macrophage migration inhibitory factor (MIF) promotes cell survival by activation of the Akt pathway and role for CSN5/JAB1 in the control of autocrine MIF activity.
    Oncogene. 2007;26:5046-59.
    PubMed     Related articles    Abstract available


    July 2007
  54. CASCIO S , Bartella V, Auriemma A, Johannes GJ, et al
    Mechanism of leptin expression in breast cancer cells: role of hypoxia-inducible factor-1alpha.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  55. VEECK J , Chorovicer M, Naami A, Breuer E, et al
    The extracellular matrix protein ITIH5 is a novel prognostic marker in invasive node-negative breast cancer and its aberrant expression is caused by promoter hypermethylation.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  56. BUDHRAM-MAHADEO VS , Irshad S, Bowen S, Lee SA, et al
    Proliferation-associated Brn-3b transcription factor can activate cyclin D1 expression in neuroblastoma and breast cancer cells.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  57. SHEN Q , Uray IP, Li Y, Krisko TI, et al
    The AP-1 transcription factor regulates breast cancer cell growth via cyclins and E2F factors.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  58. CREIGHTON CJ
    A gene transcription signature of the Akt/mTOR pathway in clinical breast tumors.
    Oncogene. 2007;26:4648-55.
    PubMed     Related articles    Abstract available


  59. DURKIN ME , Ullmannova V, Guan M, Popescu NC, et al
    Deleted in liver cancer 3 (DLC-3), a novel Rho GTPase-activating protein, is downregulated in cancer and inhibits tumor cell growth.
    Oncogene. 2007;26:4580-9.
    PubMed     Related articles    Abstract available


  60. TOMIDA S , Yanagisawa K, Koshikawa K, Yatabe Y, et al
    Identification of a metastasis signature and the DLX4 homeobox protein as a regulator of metastasis by combined transcriptome approach.
    Oncogene. 2007;26:4600-8.
    PubMed     Related articles    Abstract available


    June 2007
  61. CALDON CE , Lee CS, Sutherland RL, Musgrove EA, et al
    Wilms' tumor protein 1: an early target of progestin regulation in T-47D breast cancer cells that modulates proliferation and differentiation.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  62. MOHANKUMAR KM , Xu XQ, Zhu T, Kannan N, et al
    HOXA1-stimulated oncogenicity is mediated by selective upregulation of components of the p44/42 MAP kinase pathway in human mammary carcinoma cells.
    Oncogene. 2007;26:3998-4008.
    PubMed     Related articles    Abstract available


  63. BARTKOVA J , Horej Sbreve I Z, Sehested M, Nesland JM, et al
    DNA damage response mediators MDC1 and 53BP1: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


    May 2007
  64. SIRVENT A , Boureux A, Simon V, Leroy C, et al
    The tyrosine kinase Abl is required for Src-transforming activity in mouse fibroblasts and human breast cancer cells.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  65. ISHIZAWAR RC , Miyake T, Parsons SJ
    c-Src modulates ErbB2 and ErbB3 heterocomplex formation and function.
    Oncogene. 2007;26:3503-10.
    PubMed     Related articles    Abstract available


  66. MONTANO MM , Chaplin LJ, Deng H, Mesia-Vela S, et al
    Protective roles of quinone reductase and tamoxifen against estrogen-induced mammary tumorigenesis.
    Oncogene. 2007;26:3587-90.
    PubMed     Related articles    Abstract available


  67. COWLING VH , Cole MD
    E-cadherin repression contributes to c-Myc-induced epithelial cell transformation.
    Oncogene. 2007;26:3582-6.
    PubMed     Related articles    Abstract available


  68. GINESTIER C , Adelaide J, Goncalves A, Repellini L, et al
    ERBB2 phosphorylation and trastuzumab sensitivity of breast cancer cell lines.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  69. AMIRI A , Noei F, Jeganathan S, Kulkarni G, et al
    eEF1A2 activates Akt and stimulates Akt-dependent actin remodeling, invasion and migration.
    Oncogene. 2007;26:3027-40.
    PubMed     Related articles    Abstract available


  70. SCHAGDARSURENGIN U , Pfeifer GP, Dammann R
    Frequent epigenetic inactivation of cystatin M in breast carcinoma.
    Oncogene. 2007;26:3089-94.
    PubMed     Related articles    Abstract available


  71. MCBRYAN J , Howlin J, Kenny PA, Shioda T, et al
    ERalpha-CITED1 co-regulated genes expressed during pubertal mammary gland development: implications for breast cancer prognosis.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  72. BOSTNER J , Ahnstrom Waltersson M, Fornander T, Skoog L, et al
    Amplification of CCND1 and PAK1 as predictors of recurrence and tamoxifen resistance in postmenopausal breast cancer.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


    April 2007
  73. DAIRKEE SH , Nicolau M, Sayeed A, Champion S, et al
    Oxidative stress pathways highlighted in tumor cell immortalization: association with breast cancer outcome.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  74. SI ML , Zhu S, Wu H, Lu Z, et al
    miR-21-mediated tumor growth.
    Oncogene. 2007;26:2799-803.
    PubMed     Related articles    Abstract available


  75. BELTRAN A , Parikh S, Liu Y, Cuevas BD, et al
    Re-activation of a dormant tumor suppressor gene maspin by designed transcription factors.
    Oncogene. 2007;26:2791-8.
    PubMed     Related articles    Abstract available


  76. STANG MT , Armstrong MJ, Watson GA, Sung KY, et al
    Interferon regulatory factor-1-induced apoptosis mediated by a ligand-independent fas-associated death domain pathway in breast cancer cells.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  77. JO M , Thomas KS, Takimoto S, Gaultier A, et al
    Urokinase receptor primes cells to proliferate in response to epidermal growth factor.
    Oncogene. 2007;26:2585-94.
    PubMed     Related articles    Abstract available


  78. SAFINA A , Vandette E, Bakin AV
    ALK5 promotes tumor angiogenesis by upregulating matrix metalloproteinase-9 in tumor cells.
    Oncogene. 2007;26:2407-22.
    PubMed     Related articles    Abstract available


  79. COSACEANU D , Budiu RA, Carapancea M, Castro J, et al
    Ionizing radiation activates IGF-1R triggering a cytoprotective signaling by interfering with Ku-DNA binding and by modulating Ku86 expression via a p38 kinase-dependent mechanism.
    Oncogene. 2007;26:2423-34.
    PubMed     Related articles    Abstract available


  80. DOW LE , Kauffman JS, Caddy J, Zarbalis K, et al
    The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge.
    Oncogene. 2007;26:2272-82.
    PubMed     Related articles    Abstract available


    March 2007
  81. STREICHER KL , Yang ZQ, Draghici S, Ethier SP, et al
    Transforming function of the LSM1 oncogene in human breast cancers with the 8p11-12 amplicon.
    Oncogene. 2007;26:2104-14.
    PubMed     Related articles    Abstract available


  82. CHIN SF , Wang Y, Thorne NP, Teschendorff AE, et al
    Using array-comparative genomic hybridization to define molecular portraits of primary breast cancers.
    Oncogene. 2007;26:1959-70.
    PubMed     Related articles    Abstract available


  83. SPANKUCH B , Kurunci-Csacsko E, Kaufmann M, Strebhardt K, et al
    Rational combinations of siRNAs targeting Plk1 with breast cancer drugs.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  84. PERKS CM , Vernon EG, Rosendahl AH, Tonge D, et al
    IGF-II and IGFBP-2 differentially regulate PTEN in human breast cancer cells.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  85. KUNDU CN , Balusu R, Jaiswal AS, Gairola CG, et al
    Cigarette smoke condensate-induced level of adenomatous polyposis coli blocks long-patch base excision repair in breast epithelial cells.
    Oncogene. 2007;26:1428-38.
    PubMed     Related articles    Abstract available


    January 2007
  86. APPIERTO V , Villani MG, Cavadini E, Gariboldi M, et al
    Analysis of gene expression identifies PLAB as a mediator of the apoptotic activity of fenretinide in human ovarian cancer cells.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


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