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Amedeo Prize 2008
The 21 Finalists


  Head and Neck Cancer

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Articles published in J Clin Oncol

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Single Articles


    April 2008
  1. SEIWERT TY , Haraf DJ, Cohen EE, Stenson K, et al
    Phase I study of bevacizumab added to fluorouracil- and hydroxyurea-based concomitant chemoradiotherapy for poor-prognosis head and neck cancer.
    J Clin Oncol. 2008;26:1732-41.
    PubMed     Related articles    Abstract available


    March 2008
  2. YU JB , Blitzblau RC, Decker RH, Housman DM, et al
    Analysis of primary CD30+ cutaneous lymphoproliferative disease and survival from the Surveillance, Epidemiology, and End Results database.
    J Clin Oncol. 2008;26:1483-8.
    PubMed     Related articles    Abstract available


  3. AL-BATRAN SE , Hartmann JT, Probst S, Schmalenberg H, et al
    Phase III trial in metastatic gastroesophageal adenocarcinoma with fluorouracil, leucovorin plus either oxaliplatin or cisplatin: a study of the Arbeitsgemeinschaft Internistische Onkologie.
    J Clin Oncol. 2008;26:1435-42.
    PubMed     Related articles    Abstract available


  4. TEPPER J , Krasna MJ, Niedzwiecki D, Hollis D, et al
    Phase III trial of trimodality therapy with cisplatin, fluorouracil, radiotherapy, and surgery compared with surgery alone for esophageal cancer: CALGB 9781.
    J Clin Oncol. 2008;26:1086-92.
    PubMed     Related articles    Abstract available


  5. RUDIN CM , Liu W, Desai A, Karrison T, et al
    Pharmacogenomic and pharmacokinetic determinants of erlotinib toxicity.
    J Clin Oncol. 2008;26:1119-27.
    PubMed     Related articles    Abstract available


    February 2008
  6. CHATURVEDI AK , Engels EA, Anderson WF, Gillison ML, et al
    Incidence trends for human papillomavirus-related and -unrelated oral squamous cell carcinomas in the United States.
    J Clin Oncol. 2008;26:612-9.
    PubMed     Related articles    Abstract available


    January 2008
  7. KAWAGUCHI H , El-Naggar AK, Papadimitrakopoulou V, Ren H, et al
    Podoplanin: a novel marker for oral cancer risk in patients with oral premalignancy.
    J Clin Oncol. 2008;26:354-60.
    PubMed     Related articles    Abstract available


  8. KHURI FR , Shin DM
    Head and neck cancer chemoprevention gets a shot in the arm.
    J Clin Oncol. 2008;26:345-7.
    PubMed     Related articles   


  9. GOITEIN M , Cox JD
    Should randomized clinical trials be required for proton radiotherapy?
    J Clin Oncol. 2008;26:175-6.
    PubMed     Related articles   


  10. GRALOW J , Ozols RF, Bajorin DF, Cheson BD, et al
    Clinical cancer advances 2007: major research advances in cancer treatment, prevention, and screening--a report from the American Society of Clinical Oncology.
    J Clin Oncol. 2008;26:313-25.
    PubMed     Related articles    Abstract available


    December 2007
  11. ALLEN AM , Rabin MS, Reilly JJ, Mentzer SJ, et al
    Unresectable adenoid cystic carcinoma of the trachea treated with chemoradiation.
    J Clin Oncol. 2007;25:5521-3.
    PubMed     Related articles   


    November 2007
  12. GLYNNE-JONES R , Hoskin P
    Neoadjuvant cisplatin chemotherapy before chemoradiation: a flawed paradigm?
    J Clin Oncol. 2007;25:5281-6.
    PubMed     Related articles    Abstract available


  13. CHEN C , Kane M, Song J, Campana J, et al
    Phase I trial of gefitinib in combination with radiation or chemoradiation for patients with locally advanced squamous cell head and neck cancer.
    J Clin Oncol. 2007;25:4880-6.
    PubMed     Related articles    Abstract available


  14. KAM MK , Leung SF, Zee B, Chau RM, et al
    Prospective randomized study of intensity-modulated radiotherapy on salivary gland function in early-stage nasopharyngeal carcinoma patients.
    J Clin Oncol. 2007;25:4873-9.
    PubMed     Related articles    Abstract available


  15. DIEZ O , Gutierrez-Enriquez S, Ramon y Cajal T, Alonso C, et al
    Caution should be used when interpreting alterations affecting the exon 3 of the BRCA2 gene in breast/ovarian cancer families.
    J Clin Oncol. 2007;25:5035-6.
    PubMed     Related articles   


  16. CREHANGE G , Maingon P, Peignaux K, N'guyen TD, et al
    Phase III trial of protracted compared with split-course chemoradiation for esophageal carcinoma: Federation Francophone de Cancerologie Digestive 9102.
    J Clin Oncol. 2007;25:4895-901.
    PubMed     Related articles    Abstract available


  17. EISBRUCH A
    Reducing xerostomia by IMRT: what may, and may not, be achieved.
    J Clin Oncol. 2007;25:4863-4.
    PubMed     Related articles   


    October 2007
  18. LANGER CJ , Harris J, Horwitz EM, Nicolaou N, et al
    Phase II Study of Low-Dose Paclitaxel and Cisplatin in Combination With Split-Course Concomitant Twice-Daily Reirradiation in Recurrent Squamous Cell Carcinoma of the Head and Neck: Results of Radiation Therapy Oncology Group Protocol 9911.
    J Clin Oncol. 2007;25:4800-5.
    PubMed     Related articles    Abstract available


    September 2007
  19. SIZER KC
    Heat shock protein 70, erythropoietin, and cancer.
    J Clin Oncol. 2007;25:4326.
    PubMed     Related articles   


  20. AJANI JA , Correa AM, Swisher SG, Wu TT, et al
    For localized gastroesophageal cancer, you give chemoradiation before surgery, but then what happens?
    J Clin Oncol. 2007;25:4315-6.
    PubMed     Related articles   


  21. SALAMA JK , Seiwert TY, Vokes EE
    Chemoradiotherapy for locally advanced head and neck cancer.
    J Clin Oncol. 2007;25:4118-26.
    PubMed     Related articles   


  22. KLEINBERG L , Forastiere AA
    Chemoradiation in the management of esophageal cancer.
    J Clin Oncol. 2007;25:4110-7.
    PubMed     Related articles    Abstract available


  23. BENTZEN SM , Trotti A
    Evaluation of early and late toxicities in chemoradiation trials.
    J Clin Oncol. 2007;25:4096-103.
    PubMed     Related articles    Abstract available


  24. RUHSTALLER T , Thuerlimann B, Koeberle D, von Moos R, et al
    Is surgery still part of local therapy in patients with locally advanced esophageal carcinoma?
    J Clin Oncol. 2007;25:4025-6.
    PubMed     Related articles   


  25. AGULNIK M , Cohen EW, Cohen RB, Chen EX, et al
    Phase II study of lapatinib in recurrent or metastatic epidermal growth factor receptor and/or erbB2 expressing adenoid cystic carcinoma and non adenoid cystic carcinoma malignant tumors of the salivary glands.
    J Clin Oncol. 2007;25:3978-84.
    PubMed     Related articles    Abstract available


  26. CMELAK AJ , Li S, Goldwasser MA, Murphy B, et al
    Phase II trial of chemoradiation for organ preservation in resectable stage III or IV squamous cell carcinomas of the larynx or oropharynx: results of Eastern Cooperative Oncology Group Study E2399.
    J Clin Oncol. 2007;25:3971-7.
    PubMed     Related articles    Abstract available


  27. SALZBURG J , Burkhardt B, Zimmermann M, Wachowski O, et al
    Prevalence, clinical pattern, and outcome of CNS involvement in childhood and adolescent non-Hodgkin's lymphoma differ by non-Hodgkin's lymphoma subtype: a Berlin-Frankfurt-Munster Group Report.
    J Clin Oncol. 2007;25:3915-22.
    PubMed     Related articles    Abstract available


    August 2007
  28. ELSER C , Siu LL, Winquist E, Agulnik M, et al
    Phase II trial of sorafenib in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or nasopharyngeal carcinoma.
    J Clin Oncol. 2007;25:3766-73.
    PubMed     Related articles    Abstract available


  29. ZUUR CL , Simis YJ, Lansdaal PE, Hart AA, et al
    Ototoxicity in a randomized phase III trial of intra-arterial compared with intravenous cisplatin chemoradiation in patients with locally advanced head and neck cancer.
    J Clin Oncol. 2007;25:3759-65.
    PubMed     Related articles    Abstract available


  30. KELSEN DP , Winter KA, Gunderson LL, Mortimer J, et al
    Long-term results of RTOG trial 8911 (USA Intergroup 113): a random assignment trial comparison of chemotherapy followed by surgery compared with surgery alone for esophageal cancer.
    J Clin Oncol. 2007;25:3719-25.
    PubMed     Related articles    Abstract available


  31. KOZYREVA ON , Mezentsev DA, King DR, Gomez-Fernandez CR, et al
    Asymptomatic muscle metastases from esophageal adenocarcinoma.
    J Clin Oncol. 2007;25:3780-3.
    PubMed     Related articles   


  32. AJANI JA , Moiseyenko VM, Tjulandin S, Majlis A, et al
    Quality of life with docetaxel plus cisplatin and fluorouracil compared with cisplatin and fluorouracil from a phase III trial for advanced gastric or gastroesophageal adenocarcinoma: the V-325 Study Group.
    J Clin Oncol. 2007;25:3210-6.
    PubMed     Related articles    Abstract available


  33. AJANI JA , Moiseyenko VM, Tjulandin S, Majlis A, et al
    Clinical benefit with docetaxel plus fluorouracil and cisplatin compared with cisplatin and fluorouracil in a phase III trial of advanced gastric or gastroesophageal cancer adenocarcinoma: the V-325 Study Group.
    J Clin Oncol. 2007;25:3205-9.
    PubMed     Related articles    Abstract available


  34. ILSON DH
    Docetaxel, Cisplatin, and Fluorouracil in gastric cancer: does the punishment fit the crime?
    J Clin Oncol. 2007;25:3188-90.
    PubMed     Related articles   


    July 2007
  35. FREEDMAN RA , Wirth LJ, Chirieac LR, Huang EC, et al
    Glioblastoma in a patient with early-stage tonsil cancer.
    J Clin Oncol. 2007;25:2848-50.
    PubMed     Related articles   


  36. LONGO R , Torino F, Castellana M, Amici S, et al
    Skin acrometastases in squamous cell carcinoma of the tongue.
    J Clin Oncol. 2007;25:2847-8.
    PubMed     Related articles   


    June 2007
  37. LEE MJ , Kim EK, Kim MJ, Kwak JY, et al
    Spontaneous pneumothorax in metastatic thyroid papillary carcinoma.
    J Clin Oncol. 2007;25:2616-8.
    PubMed     Related articles   


  38. MACHENS A , Dralle H
    Bronchoalveolar lavage for diagnosis of miliary lung metastases from papillary thyroid carcinoma.
    J Clin Oncol. 2007;25:2495-6.
    PubMed     Related articles   


  39. COHEN A , Rovelli A, Merlo DF, van Lint MT, et al
    Risk for secondary thyroid carcinoma after hematopoietic stem-cell transplantation: an EBMT Late Effects Working Party Study.
    J Clin Oncol. 2007;25:2449-54.
    PubMed     Related articles    Abstract available


  40. STEYERBERG EW , Neville B, Weeks JC, Earle CC, et al
    Referral patterns, treatment choices, and outcomes in locoregional esophageal cancer: a population-based analysis of elderly patients.
    J Clin Oncol. 2007;25:2389-96.
    PubMed     Related articles    Abstract available


  41. CURRAN D , Giralt J, Harari PM, Ang KK, et al
    Quality of life in head and neck cancer patients after treatment with high-dose radiotherapy alone or in combination with cetuximab.
    J Clin Oncol. 2007;25:2191-7.
    PubMed     Related articles    Abstract available


  42. AGULNIK M , da Cunha Santos G, Hedley D, Nicklee T, et al
    Predictive and pharmacodynamic biomarker studies in tumor and skin tissue samples of patients with recurrent or metastatic squamous cell carcinoma of the head and neck treated with erlotinib.
    J Clin Oncol. 2007;25:2184-90.
    PubMed     Related articles    Abstract available


  43. SIU LL , Soulieres D, Chen EX, Pond GR, et al
    Phase I/II trial of erlotinib and cisplatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck: a Princess Margaret Hospital phase II consortium and National Cancer Institute of Canada Clinical Trials Group Study.
    J Clin Oncol. 2007;25:2178-83.
    PubMed     Related articles    Abstract available


  44. VERMORKEN JB , Trigo J, Hitt R, Koralewski P, et al
    Open-label, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based
    J Clin Oncol. 2007;25:2171-7.
    PubMed     Related articles    Abstract available


  45. TEMAM S , Kawaguchi H, El-Naggar AK, Jelinek J, et al
    Epidermal growth factor receptor copy number alterations correlate with poor clinical outcome in patients with head and neck squamous cancer.
    J Clin Oncol. 2007;25:2164-70.
    PubMed     Related articles    Abstract available


  46. FORASTIERE AA , Burtness BA
    Epidermal growth factor receptor inhibition in head and neck cancer--more insights, but more questions.
    J Clin Oncol. 2007;25:2152-5.
    PubMed     Related articles   


    May 2007
  47. HIGGINSON DS , Brahmer J, Tufano RP, Bajaj GK, et al
    Pleural mesothelioma metastatic to tongue.
    J Clin Oncol. 2007;25:2133-5.
    PubMed     Related articles   


  48. AGARWAL N , Gordeuk VR, Prchal JT
    Are erythropoietin receptors expressed in tumors? Facts and fiction--more careful studies are needed.
    J Clin Oncol. 2007;25:1813-4.
    PubMed     Related articles   


    April 2007
  49. JELKMANN W , Laugsch M
    Problems in identifying functional erythropoietin receptors in cancer tissue.
    J Clin Oncol. 2007;25:1627-8.
    PubMed     Related articles   


  50. CLAVO B
    Do erythropoietin receptors on cancer cells explain unexpected clinical findings?
    J Clin Oncol. 2007;25:1447-8.
    PubMed     Related articles   


  51. GANLY I , Talbot S, Carlson D, Viale A, et al
    Identification of angiogenesis/metastases genes predicting chemoradiotherapy response in patients with laryngopharyngeal carcinoma.
    J Clin Oncol. 2007;25:1369-76.
    PubMed     Related articles    Abstract available


  52. BASU S , Alavi A
    Bone marrow and not bone is the primary site for skeletal metastasis: critical role of [18F]fluorodeoxyglucose positron emission tomography in this setting.
    J Clin Oncol. 2007;25:1297.
    PubMed     Related articles   


  53. BEDENNE L , Michel P, Bouche O, Milan C, et al
    Chemoradiation followed by surgery compared with chemoradiation alone in squamous cancer of the esophagus: FFCD 9102.
    J Clin Oncol. 2007;25:1160-8.
    PubMed     Related articles    Abstract available


  54. ILSON DH
    Surgery after primary chemoradiotherapy in squamous cancer of the esophagus: is the photon mightier than the sword?
    J Clin Oncol. 2007;25:1155-6.
    PubMed     Related articles   


    March 2007
  55. FENG M , Eisbruch A
    Future issues in highly conformal radiotherapy for head and neck cancer.
    J Clin Oncol. 2007;25:1009-13.
    PubMed     Related articles    Abstract available


  56. BRADA M , Pijls-Johannesma M, De Ruysscher D
    Proton therapy in clinical practice: current clinical evidence.
    J Clin Oncol. 2007;25:965-70.
    PubMed     Related articles   


  57. PERSONENI N
    Outcome prediction to erlotinib in gastroesophageal adenocarcinomas: can we improve epidermal growth factor receptor and phospho-AKT testing?
    J Clin Oncol. 2007;25:910.
    PubMed     Related articles   


  58. PEDRAZZANI C , de Manzoni G, Marrelli D, Roviello F, et al
    It is time for a proper staging system for adenocarcinoma of the gastroesophageal junction.
    J Clin Oncol. 2007;25:907-8.
    PubMed     Related articles   


  59. AJANI JA
    New proposal for postsurgery pathologic staging of esophageal or gastroesophageal junction adenocarcinoma: why bother?
    J Clin Oncol. 2007;25:906-7.
    PubMed     Related articles   


  60. MOLLING JW , Langius JA, Langendijk JA, Leemans CR, et al
    Low levels of circulating invariant natural killer T cells predict poor clinical outcome in patients with head and neck squamous cell carcinoma.
    J Clin Oncol. 2007;25:862-8.
    PubMed     Related articles    Abstract available


    February 2007
  61. THANKAPPAN K
    Recommended organ preservation strategy for T2 unfavorable glottis cancer.
    J Clin Oncol. 2007;25:735-6.
    PubMed     Related articles   


  62. IZZO JG , Wu TT, Wu X, Ensor J, et al
    Cyclin D1 guanine/adenine 870 polymorphism with altered protein expression is associated with genomic instability and aggressive clinical biology of esophageal adenocarcinoma.
    J Clin Oncol. 2007;25:698-707.
    PubMed     Related articles    Abstract available


  63. ALLEN AM , Haddad RI, Tishler RB
    Retropharyngeal nodes in hypopharynx cancer on positron emission tomography.
    J Clin Oncol. 2007;25:599-601.
    PubMed     Related articles   


  64. RIZK NP , Venkatraman E, Bains MS, Park B, et al
    American Joint Committee on Cancer staging system does not accurately predict survival in patients receiving multimodality therapy for esophageal adenocarcinoma.
    J Clin Oncol. 2007;25:507-12.
    PubMed     Related articles    Abstract available


  65. TEBBI CK , London WB, Friedman D, Villaluna D, et al
    Dexrazoxane-associated risk for acute myeloid leukemia/myelodysplastic syndrome and other secondary malignancies in pediatric Hodgkin's disease.
    J Clin Oncol. 2007;25:493-500.
    PubMed     Related articles    Abstract available


    January 2007
  66. OZOLS RF , Herbst RS, Colson YL, Gralow J, et al
    Clinical cancer advances 2006: major research advances in cancer treatment, prevention, and screening--a report from the American Society of Clinical Oncology.
    J Clin Oncol. 2007;25:146-62.
    PubMed     Related articles    Abstract available


    December 2006
  67. GILLISON ML
    Human papillomavirus and prognosis of oropharyngeal squamous cell carcinoma: implications for clinical research in head and neck cancers.
    J Clin Oncol. 2006;24:5623-5.
    PubMed     Related articles   


  68. VERMEER-MENS JC , Goemaere NN, Kuenen-Boumeester V, de Muinck Keizer-Schrama SM, et al
    Childhood papillary thyroid carcinoma with miliary pulmonary metastases.
    J Clin Oncol. 2006;24:5788-9.
    PubMed     Related articles   


  69. LICITRA L , Perrone F, Bossi P, Suardi S, et al
    High-risk human papillomavirus affects prognosis in patients with surgically treated oropharyngeal squamous cell carcinoma.
    J Clin Oncol. 2006;24:5630-6.
    PubMed     Related articles    Abstract available


  70. PERSONENI N
    Epidermal growth factor receptor gene copy number in esophageal cancer and outcome prediction to gefitinib: does intratumoral heterogeneity matter?
    J Clin Oncol. 2006;24:5465.
    PubMed     Related articles   


  71. LEUNG SF , Zee B, Ma BB, Hui EP, et al
    Plasma epstein-barr viral deoxyribonucleic Acid quantitation complements tumor-node-metastasis staging prognostication in nasopharyngeal carcinoma.
    J Clin Oncol. 2006;24:5414-8.
    PubMed     Related articles    Abstract available


    November 2006
  72. CHOI YM , Mafee MF, Feldman LE
    Successful treatment of syncope in head and neck cancer with induction chemotherapy.
    J Clin Oncol. 2006;24:5332-3.
    PubMed     Related articles   


  73. PETRIK D , Lavori PW, Cao H, Zhu Y, et al
    Plasma osteopontin is an independent prognostic marker for head and neck cancers.
    J Clin Oncol. 2006;24:5291-7.
    PubMed     Related articles    Abstract available


  74. SHAH MA , Ramanathan RK, Ilson DH, Levnor A, et al
    Multicenter phase II study of irinotecan, cisplatin, and bevacizumab in patients with metastatic gastric or gastroesophageal junction adenocarcinoma.
    J Clin Oncol. 2006;24:5201-6.
    PubMed     Related articles    Abstract available


  75. GRIFFITH OL , Melck A, Jones SJ, Wiseman SM, et al
    Meta-analysis and meta-review of thyroid cancer gene expression profiling studies identifies important diagnostic biomarkers.
    J Clin Oncol. 2006;24:5043-51.
    PubMed     Related articles    Abstract available


  76. PARK SM , Lim MK, Shin SA, Yun YH, et al
    Impact of prediagnosis smoking, alcohol, obesity, and insulin resistance on survival in male cancer patients: National Health Insurance Corporation Study.
    J Clin Oncol. 2006;24:5017-24.
    PubMed     Related articles    Abstract available


    October 2006
  77. DRAGOVICH T , McCoy S, Fenoglio-Preiser CM, Wang J, et al
    Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127.
    J Clin Oncol. 2006;24:4922-7.
    PubMed     Related articles    Abstract available


  78. HENKE M , Mattern D, Pepe M, Bezay C, et al
    Do erythropoietin receptors on cancer cells explain unexpected clinical findings?
    J Clin Oncol. 2006;24:4708-13.
    PubMed     Related articles    Abstract available


  79. OTT K , Weber WA, Lordick F, Becker K, et al
    Metabolic imaging predicts response, survival, and recurrence in adenocarcinomas of the esophagogastric junction.
    J Clin Oncol. 2006;24:4692-8.
    PubMed     Related articles    Abstract available


    September 2006
  80. NG SH , Yen TC, Chang JT, Chan SC, et al
    Prospective study of [18F]fluorodeoxyglucose positron emission tomography and computed tomography and magnetic resonance imaging in oral cavity squamous cell carcinoma with palpably negative neck.
    J Clin Oncol. 2006;24:4371-6.
    PubMed     Related articles    Abstract available


  81. WALDRON JN
    Fluorodeoxyglucose positron emission tomography for the preoperative staging of oral cavity cancers: only one piece of the puzzle.
    J Clin Oncol. 2006;24:4367-8.
    PubMed     Related articles   


  82. LAGARDE SM , ten Kate FJ, Reitsma JB, Busch OR, et al
    Prognostic factors in adenocarcinoma of the esophagus or gastroesophageal junction.
    J Clin Oncol. 2006;24:4347-55.
    PubMed     Related articles    Abstract available


    May 2006

  83. Expressions of concern.
    J Clin Oncol. 2006;24:2404.
    PubMed     Related articles   


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