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The Medical Article of the Year 2008:
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78.
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  Pulmonary Hypertension

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Articles published in Circ Res

Retrieve available abstracts of 28 articles:
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Single Articles


    May 2008
  1. YANG J , Davies RJ, Southwood M, Long L, et al
    Mutations in bone morphogenetic protein type II receptor cause dysregulation of Id gene expression in pulmonary artery smooth muscle cells: implications for familial pulmonary arterial hypertension.
    Circ Res. 2008;102:1212-21.
    PubMed     Related articles    Abstract available


  2. NEMENOFF RA , Simpson PA, Furgeson SB, Kaplan-Albuquerque N, et al
    Targeted deletion of PTEN in smooth muscle cells results in vascular remodeling and recruitment of progenitor cells through induction of stromal cell-derived factor-1alpha.
    Circ Res. 2008;102:1036-45.
    PubMed     Related articles    Abstract available


    February 2008
  3. EL-BIZRI N , Wang L, Merklinger SL, Guignabert C, et al
    Smooth muscle protein 22alpha-mediated patchy deletion of Bmpr1a impairs cardiac contractility but protects against pulmonary vascular remodeling.
    Circ Res. 2008;102:380-8.
    PubMed     Related articles    Abstract available


  4. FARROW KN , Groh BS, Schumacker PT, Lakshminrusimha S, et al
    Hyperoxia increases phosphodiesterase 5 expression and activity in ovine fetal pulmonary artery smooth muscle cells.
    Circ Res. 2008;102:226-33.
    PubMed     Related articles    Abstract available   Free Full Text


    September 2007
  5. ITO T , Okada T, Miyashita H, Nomoto T, et al
    Interleukin-10 expression mediated by an adeno-associated virus vector prevents monocrotaline-induced pulmonary arterial hypertension in rats.
    Circ Res. 2007;101:734-41.
    PubMed     Related articles    Abstract available


    August 2007
  6. SANDERS KA , Hoidal JR
    The NOX on pulmonary hypertension.
    Circ Res. 2007;101:224-6.
    PubMed     Related articles   


  7. MITTAL M , Roth M, Konig P, Hofmann S, et al
    Hypoxia-dependent regulation of nonphagocytic NADPH oxidase subunit NOX4 in the pulmonary vasculature.
    Circ Res. 2007;101:258-67.
    PubMed     Related articles    Abstract available


    June 2007
  8. FENG N , Hoover DB, Paolocci N
    Forever young?: nerve growth factor, sympathetic fibers, and right ventricle pressure overload.
    Circ Res. 2007;100:1670-2.
    PubMed     Related articles   


  9. KIMURA K , Ieda M, Kanazawa H, Yagi T, et al
    Cardiac sympathetic rejuvenation: a link between nerve function and cardiac hypertrophy.
    Circ Res. 2007;100:1755-64.
    PubMed     Related articles    Abstract available


    March 2007
  10. OKA M , Homma N, Taraseviciene-Stewart L, Morris KG, et al
    Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats.
    Circ Res. 2007;100:923-9.
    PubMed     Related articles    Abstract available


    September 2006
  11. STENMARK KR , Fagan KA, Frid MG
    Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms.
    Circ Res. 2006;99:675-91.
    PubMed     Related articles    Abstract available


    August 2006
  12. WU X , Chang MS, Mitsialis SA, Kourembanas S, et al
    Hypoxia regulates bone morphogenetic protein signaling through C-terminal-binding protein 1.
    Circ Res. 2006;99:240-7.
    PubMed     Related articles    Abstract available


    June 2006
  13. AARONSON PI
    TRPC Channel upregulation in chronically hypoxic pulmonary arteries: the HIF-1 bandwagon gathers steam.
    Circ Res. 2006;98:1465-7.
    PubMed     Related articles   


    May 2006
  14. DE CAESTECKER M
    Serotonin signaling in pulmonary hypertension.
    Circ Res. 2006;98:1229-31.
    PubMed     Related articles   


    April 2006
  15. GUIGNABERT C , Izikki M, Tu LI, Li Z, et al
    Transgenic Mice Overexpressing the 5-Hydroxytryptamine Transporter Gene in Smooth Muscle Develop Pulmonary Hypertension.
    Circ Res. 2006;.
    PubMed     Related articles    Abstract available


    March 2006
  16. BELAIBA RS , Djordjevic T, Bonello S, Artunc F, et al
    The serum- and glucocorticoid-inducible kinase Sgk-1 is involved in pulmonary vascular remodeling: role in redox-sensitive regulation of tissue factor by thrombin.
    Circ Res. 2006;98:828-36.
    PubMed     Related articles    Abstract available


    February 2006
  17. LONG L , Maclean MR, Jeffery TK, Morecroft I, et al
    Serotonin Increases Susceptibility to Pulmonary Hypertension in BMPR2-Deficient Mice.
    Circ Res. 2006;.
    PubMed     Related articles    Abstract available


  18. MICHELAKIS ED
    Spatio-temporal diversity of apoptosis within the vascular wall in pulmonary arterial hypertension: heterogeneous BMP signaling may have therapeutic implications.
    Circ Res. 2006;98:172-5.
    PubMed     Related articles   


    December 2005
  19. TEICHERT-KULISZEWSKA K , Kutryk MJ, Kuliszewski MA, Karoubi G, et al
    Bone Morphogenetic Protein Receptor-2 Signaling Promotes Pulmonary Arterial Endothelial Cell Survival. Implications for Loss-of-Function Mutations in the Pathogenesis of Pulmonary Hypertension.
    Circ Res 2005;.
    PubMed     Related articles    Abstract available


    September 2005
  20. YU L , Quinn DA, Garg HG, Hales CA, et al
    Cyclin-Dependent Kinase Inhibitor p27Kip1, but not p21WAF1/Cip1, Is Required for Inhibition of Hypoxia-Induced Pulmonary Hypertension and Remodeling by Heparin in Mice.
    Circ Res 2005;.
    PubMed     Related articles    Abstract available


    August 2005
  21. MERKLINGER SL , Wagner RA, Spiekerkoetter E, Hinek A, et al
    Increased Fibulin-5 and Elastin in S100A4/Mts1 Mice With Pulmonary Hypertension.
    Circ Res 2005;.
    PubMed     Related articles    Abstract available


  22. FRANK DB , Abtahi A, Yamaguchi DJ, Manning S, et al
    Bone Morphogenetic Protein 4 Promotes Pulmonary Vascular Remodeling in Hypoxic Pulmonary Hypertension.
    Circ Res 2005;.
    PubMed     Related articles    Abstract available


  23. LAWRIE A , Spiekerkoetter E, Martinez EC, Ambartsumian N, et al
    Interdependent serotonin transporter and receptor pathways regulate S100A4/Mts1, a gene associated with pulmonary vascular disease.
    Circ Res 2005;97:227-35.
    PubMed     Related articles    Abstract available


    July 2005
  24. STENMARK KR , McMurtry IF
    Vascular remodeling versus vasoconstriction in chronic hypoxic pulmonary hypertension: a time for reappraisal?
    Circ Res 2005;97:95-8.
    PubMed     Related articles   


  25. HYVELIN JM , Howell K, Nichol A, Costello CM, et al
    Inhibition of Rho-kinase attenuates hypoxia-induced angiogenesis in the pulmonary circulation.
    Circ Res 2005;97:185-91.
    PubMed     Related articles    Abstract available


    May 2005
  26. STEWART DJ
    Bone morphogenetic protein receptor-2 and pulmonary arterial hypertension: unraveling a riddle inside an enigma?
    Circ Res 2005;96:1033-5.
    PubMed     Related articles   


  27. YANG X , Long L, Southwood M, Rudarakanchana N, et al
    Dysfunctional Smad signaling contributes to abnormal smooth muscle cell proliferation in familial pulmonary arterial hypertension.
    Circ Res 2005;96:1053-63.
    PubMed     Related articles    Abstract available


    March 2005
  28. ZHAO YD , Courtman DW, Deng Y, Kugathasan L, et al
    Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrow-derived endothelial-like progenitor cells: efficacy of combined cell and eNOS gene therapy in established disease.
    Circ Res 2005;96:442-50.
    PubMed     Related articles    Abstract available


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