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Pulmonary Hypertension

Free Subscription Articles published in Circulation Retrieve available abstracts of 64 articles: HTML format

Single Articles

June 2026
1. WANG Q, Tian J, Liu D, Zheng T, et al
   Endothelial SHMT2 Drives Pulmonary Vascular Remodeling Through Noncanonical Pathway in Pulmonary Hypertension.
   Circulation. 2026 Jun 10. doi: 10.1161/CIRCULATIONAHA.125.066183.
   PubMed     Abstract available
   
   
   May 2026
2. TORO V, Mougin M, Brossat C, Jambon-Barbara C, et al
   Correction to: Breast Cancer Reveals Latent BMPR2-Related Susceptibility to Pulmonary Hypertension.
   Circulation. 2026;153:e1362.
   PubMed    
   
   
   
3. HOU Y, Li Q, Wei TW, Lin X, et al
   Hypoxia Upregulation of BACH1 Aggravates Pulmonary Hypertension Through TGFBR2/SMAD Pathways.
   Circulation. 2026 May 26. doi: 10.1161/CIRCULATIONAHA.124.073606.
   PubMed     Abstract available
   
   
   
4. SARMA S, Chin KM
   Stepping Into a New Era: Sotatercept for the Treatment of Combined Precapillary and Postcapillary Pulmonary Hypertension From Heart Failure With Preserved Ejection Fraction.
   Circulation. 2026;153:1460-1462.
   PubMed    
   
   
   
5. LI R, Tang Y, Ding Y, Hu P, et al
   GPRASP1 Safeguards Endothelial Aspartate Metabolism to Prevent Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction.
   Circulation. 2026 May 7. doi: 10.1161/CIRCULATIONAHA.126.079030.
   PubMed     Abstract available
   
   
   April 2026
6. PULLAMSETTI SS, Vanderpool RR, de Man F, de Jesus Perez VA, et al
   Advanced Molecular, Metabolic, and Imaging Approaches to Characterizing Right Ventricular Failure: A Scientific Statement From the American Heart Association.
   Circulation. 2026 Apr 2. doi: 10.1161/CIR.0000000000001422.
   PubMed     Abstract available
   
   
   March 2026
7. FORBES LM, Cornwell WK
   Group 1 Pulmonary Hypertension With Elevated Pulmonary Artery Wedge Pressure: Characterizing A Complex Phenotype.
   Circulation. 2026;153:963-966.
   PubMed    
   
   
   
8. GOMBERG-MAITLAND M, Tedford RJ, Langleben D, Rosenkranz S, et al
   Sotatercept for Combined Post- and Pre-capillary Pulmonary Hypertension Associated With Heart Failure: Results from the Phase 2, Randomized, Placebo-Controlled CADENCE Study.
   Circulation. 2026 Mar 29. doi: 10.1161/CIRCULATIONAHA.126.079918.
   PubMed     Abstract available
   
   
   
9. ZHANG Y, Bonnet S, Provencher S, Piao J, et al
   A Critical Contribution of Cardiac Myofibroblasts in Right Ventricular Failure and the Role of UCP2 SNPs in the Predisposition to RV Decompensation in Pulmonary Arterial Hypertension.
   Circulation. 2026 Mar 9. doi: 10.1161/CIRCULATIONAHA.125.078674.
   PubMed     Abstract available
   
   
   February 2026
10. REDDY YNV, Frantz RP, Miranda WR, Asokan AK, et al
    Elevated Pulmonary Artery Wedge Pressure in Group 1 Pulmonary Hypertension.
    Circulation. 2026 Feb 13. doi: 10.1161/CIRCULATIONAHA.125.077606.
    PubMed     Abstract available
    
    
    
11. JAMBON-BARBARA C, Suissa S, Dell'Aniello S, Hlavaty A, et al
    Second- and Third-Generation BCR-ABL Tyrosine Kinase Inhibitors and the Risk of Pulmonary Arterial Hypertension: A Prevalent New-User Design.
    Circulation. 2026 Feb 12. doi: 10.1161/CIRCULATIONAHA.125.077764.
    PubMed     Abstract available
    
    
    January 2026
12. TORO V, Mougin M, Brossat C, Jambon-Barbara C, et al
    Breast Cancer Reveals Latent BMPR2-Related Susceptibility to Pulmonary Hypertension.
    Circulation. 2026 Jan 28. doi: 10.1161/CIRCULATIONAHA.125.079067.
    PubMed     Abstract available
    
    
    
13. TADA A, Fayyaz AU, Reddy YNV, Redfield MM, et al
    Rapidly Progressive Pulmonary Hypertension: Importance of Vascular Disease Distribution.
    Circulation. 2026;153:285-289.
    PubMed    
    
    
    April 2025
14. YU Q, Tai YY, Tang Y, Zhao J, et al
    Correction to: BOLA (BolA Family Member 3) Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension.
    Circulation. 2025;151:e967.
    PubMed    
    
    
    March 2025
15. HOEPER MM, Oerke B, Wissmuller M, Leuchte H, et al
    Correction to: Tadalafil for Treatment of Combined Postcapillary and Precapillary Pulmonary Hypertension in Patients With Heart Failure and Preserved Ejection Fraction: A Randomized Controlled Phase 3 Study.
    Circulation. 2025;151:e763.
    PubMed    
    
    
    
16. DAI H, Lu X, Zhou X
    Letter by Dai et al Regarding Article, "Tadalafil for Treatment of Combined Postcapillary and Precapillary Pulmonary Hypertension in Patients With Heart Failure and Preserved Ejection Fraction".
    Circulation. 2025;151:e686.
    PubMed    
    
    
    January 2025
17. LEMAY SE, Montesinos MS, Grobs Y, Yokokawa T, et al
    Exploring Integrin alpha5beta1 as a Potential Therapeutic Target for Pulmonary Arterial Hypertension: Insights From Comprehensive Multicenter Preclinical Studies.
    Circulation. 2025 Jan 20. doi: 10.1161/CIRCULATIONAHA.124.070693.
    PubMed     Abstract available
    
    
    November 2024
18. MCLAUGHLIN VV, Humbert M
    Pulmonary Hypertension: From Therapeutic Nihilism to Multiple Therapeutic Interventions.
    Circulation. 2024;150:1653-1655.
    PubMed    
    
    
    October 2024
19. DELCROIX M, Pepke-Zaba J, D'Armini AM, Fadel E, et al
    Worldwide CTEPH Registry: Long-Term Outcomes With Pulmonary Endarterectomy, Balloon Pulmonary Angioplasty, and Medical Therapy.
    Circulation. 2024;150:1354-1365.
    PubMed     Abstract available
    
    
    August 2024
20. HONG J, Medzikovic L, Sun W, Wong B, et al
    Integrative Multiomics in the Lung Reveals a Protective Role of Asporin in Pulmonary Arterial Hypertension.
    Circulation. 2024 Aug 21. doi: 10.1161/CIRCULATIONAHA.124.069864.
    PubMed     Abstract available
    
    
    July 2024
21. LIU B, Yi D, Xia X, Ramirez K, et al
    General Capillary Endothelial Cells Undergo Reprogramming Into Arterial Endothelial Cells in Pulmonary Hypertension Through HIF-2alpha/Notch4 Pathway.
    Circulation. 2024;150:414-417.
    PubMed    
    
    
    June 2024
22. HOEPER MM, Oerke B, Wissmuller M, Leuchte H, et al
    Tadalafil for Treatment of Combined Postcapillary and Precapillary Pulmonary Hypertension in Patients With Heart Failure and Preserved Ejection Fraction: A Randomized Controlled Phase 3 Study.
    Circulation. 2024 Jun 28. doi: 10.1161/CIRCULATIONAHA.124.069340.
    PubMed     Abstract available
    
    
    
23. ZHANG Q, Yaoita N, Tabuchi A, Liu S, et al
    Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension.
    Circulation. 2024 Jun 14. doi: 10.1161/CIRCULATIONAHA.124.068726.
    PubMed     Abstract available
    
    
    
24. 
    Correction to: Status and Future Directions for Balloon Pulmonary Angioplasty in Chronic Thromboembolic Pulmonary Disease With and Without Pulmonary Hypertension: A Scientific Statement From the American Heart Association.
    Circulation. 2024;149:e1412.
    PubMed    
    
    
    May 2024
25. SALAHUDDIN A, Harris IS, Sabanayagam A
    Double Whammy Complicating Management of Pulmonary Hypertension.
    Circulation. 2024;149:1770-1774.
    PubMed    
    
    
    
26. JHENG JR, Bai Y, Noda K, Huot JR, et al
    Skeletal Muscle SIRT3 Deficiency Contributes to Pulmonary Vascular Remodeling in Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction.
    Circulation. 2024 May 28. doi: 10.1161/CIRCULATIONAHA.124.068624.
    PubMed     Abstract available
    
    
    
27. HOEPER MM, Ewert R, Jansa P, Sirenko Y, et al
    Randomized, Multicenter Study to Assess the Effects of Different Doses of Sildenafil on Mortality in Adults With Pulmonary Arterial Hypertension.
    Circulation. 2024 May 16. doi: 10.1161/CIRCULATIONAHA.123.068107.
    PubMed     Abstract available
    
    
    
28. RUBIN LJ
    Is There a Role for Calcium Channel Blockers in the Contemporary Treatment Paradigm for Pulmonary Arterial Hypertension?
    Circulation. 2024;149:1565-1567.
    PubMed    
    
    
    
29. TANG H, Gupta A, Morrisroe SA, Bao C, et al
    Deficiency of the Deubiquitinase UCHL1 Attenuates Pulmonary Arterial Hypertension.
    Circulation. 2024 May 2. doi: 10.1161/CIRCULATIONAHA.123.065304.
    PubMed     Abstract available
    
    
    April 2024
30. BORDAN Z, Batori R, Haigh S, Li X, et al
    PDZ-Binding Kinase, a Novel Regulator of Vascular Remodeling in Pulmonary Arterial Hypertension.
    Circulation. 2024 Apr 29. doi: 10.1161/CIRCULATIONAHA.123.067095.
    PubMed     Abstract available
    
    
    
31. RAO RJ, Chan SY
    Mediating Metabolism: Inhibition of Malic Enzyme 1 (ME1) Restores Endothelial Bioenergetics and Adenosine Signaling in Pulmonary Hypertension.
    Circulation. 2024;149:1372-1374.
    PubMed    
    
    
    
32. GERHARDT F, Fiessler E, Olsson KM, Kayser MZ, et al
    Positive Vasoreactivity Testing in Pulmonary Arterial Hypertension: Therapeutic Consequences, Treatment Patterns, and Outcomes in the Modern Management Era.
    Circulation. 2024 Apr 12. doi: 10.1161/CIRCULATIONAHA.122.063821.
    PubMed     Abstract available
    
    
    
33. SHEN H, Gao Y, Ge D, Tan M, et al
    BRCC3 Regulation of ALK2 in Vascular Smooth Muscle Cells: Implication in Pulmonary Hypertension.
    Circulation. 2024 Apr 1. doi: 10.1161/CIRCULATIONAHA.123.066430.
    PubMed     Abstract available
    
    
    March 2024
34. AGGARWAL V, Giri J, Visovatti SH, Mahmud E, et al
    Status and Future Directions for Balloon Pulmonary Angioplasty in Chronic Thromboembolic Pulmonary Disease With and Without Pulmonary Hypertension: A Scientific Statement From the American Heart Association.
    Circulation. 2024 Mar 7. doi: 10.1161/CIR.0000000000001197.
    PubMed     Abstract available
    
    
    February 2024
35. LUO Y, Qi X, Zhang Z, Zhang J, et al
    Inactivation of Malic Enzyme 1 in Endothelial Cells Alleviates Pulmonary Hypertension.
    Circulation. 2024 Feb 5. doi: 10.1161/CIRCULATIONAHA.123.067579.
    PubMed     Abstract available
    
    
    January 2024
36. BIAN JS, Chen J, Zhang J, Tan J, et al
    ErbB3 Governs Endothelial Dysfunction in Hypoxia-Induced Pulmonary Hypertension.
    Circulation. 2024 Jan 12. doi: 10.1161/CIRCULATIONAHA.123.067005.
    PubMed     Abstract available
    
    
    November 2023
37. WALTERS R, Vasilaki E, Wilkins MR, Zhao L, et al
    Response by Walters et al to Letter Regarding Article, "SOX17 Enhancer Variants Disrupt Transcription Factor Binding and Enhancer Inactivity Drives Pulmonary Hypertension".
    Circulation. 2023;148:1825-1826.
    PubMed    
    
    
    
38. LI G, Chen H, Ren C
    Letter by Li et al Regarding Article, "SOX17 Enhancer Variants Disrupt Transcription Factor Binding and Enhancer Inactivity Drives Pulmonary Hypertension".
    Circulation. 2023;148:1823-1824.
    PubMed    
    
    
    
39. HOSOKAWA K, Watanabe H, Taniguchi Y, Ikeda N, et al
    A Multicenter, Single-Blind, Randomized, Warfarin-Controlled Trial of Edoxaban in Patients With Chronic Thromboembolic Pulmonary Hypertension: KABUKI Trial.
    Circulation. 2023 Nov 13. doi: 10.1161/CIRCULATIONAHA.123.067528.
    PubMed    
    
    
    September 2023
40. KUEHN BM
    Experimental Drug, Combination Pill Show Promise for Treating Pulmonary Hypertension.
    Circulation. 2023;148:852-854.
    PubMed    
    
    
    July 2023
41. 
    Correction to: Heteroplasmy of Wild-Type Mitochondrial DNA Variants in Mice Causes Metabolic Heart Disease With Pulmonary Hypertension and Frailty.
    Circulation. 2023;148:e2.
    PubMed    
    
    
    May 2023
42. JANI V, Aslam MI, Fenwick AJ, Ma W, et al
    Right Ventricular Sarcomere Contractile Depression and the Role of Thick Filament Activation in Human Heart Failure With Pulmonary Hypertension.
    Circulation. 2023 May 17. doi: 10.1161/CIRCULATIONAHA.123.064717.
    PubMed     Abstract available
    
    
    
43. 
    Correction to: Gremlin Plays a Key Role in the Pathogenesis of Pulmonary Hypertension.
    Circulation. 2023;147:e718.
    PubMed    
    
    
    April 2023
44. GUIGNABERT C, Savale L, Boucly A, Thuillet R, et al
    Serum and Pulmonary Expression Profiles of the Activin Signaling System in Pulmonary Arterial Hypertension.
    Circulation. 2023 Apr 25. doi: 10.1161/CIRCULATIONAHA.122.061501.
    PubMed     Abstract available
    
    
    
45. WALTERS R, Vasilaki E, Aman J, Chen CN, et al
    SOX17 Enhancer Variants Disrupt Transcription Factor Binding And Enhancer Inactivity Drives Pulmonary Hypertension.
    Circulation. 2023 Apr 17. doi: 10.1161/CIRCULATIONAHA.122.061940.
    PubMed     Abstract available
    
    
    March 2023
46. RAJAGOPAL S, Ruetzler K, Ghadimi K, Horn EM, et al
    Evaluation and Management of Pulmonary Hypertension in Noncardiac Surgery: A Scientific Statement From the American Heart Association.
    Circulation. 2023 Mar 16. doi: 10.1161/CIR.0000000000001136.
    PubMed     Abstract available
    
    
    February 2023
47. CHIN KM, Santiago-Munoz P
    Pregnancy and Congenital Heart Disease-Associated Pulmonary Hypertension: Are Outcomes Improving?
    Circulation. 2023;147:562-564.
    PubMed    
    
    
    
48. ZHANG Q, Zhu F, Shi G, Hu C, et al
    Maternal Outcomes Among Pregnant Women With Congenital Heart Disease-Associated Pulmonary Hypertension.
    Circulation. 2023;147:549-561.
    PubMed     Abstract available
    
    
    December 2022
49. BORN E, Lipskaia L, Breau M, Houssaini A, et al
    Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression.
    Circulation. 2022 Dec 14. doi: 10.1161/CIRCULATIONAHA.122.058794.
    PubMed     Abstract available
    
    
    November 2022
50. ZHOU W, Liu K, Zeng L, He J, et al
    Targeting VEGF-A/VEGFR2 Y949 Signaling-Mediated Vascular Permeability Alleviates Hypoxic Pulmonary Hypertension.
    Circulation. 2022 Nov 17. doi: 10.1161/CIRCULATIONAHA.122.061900.
    PubMed     Abstract available
    
    
    
51. JHA AK
    Letter by Jha Regarding Article, "Latent Pulmonary Vascular Disease and Therapeutic Atrial Shunt".
    Circulation. 2022;146:e242-e243.
    PubMed    
    
    
    
52. BORLAUG BA, Shah SJ
    Response by Borlaug and Shah Regarding Article, "Latent Pulmonary Vascular Disease and Therapeutic Atrial Shunt".
    Circulation. 2022;146:e244-e245.
    PubMed    
    
    
    September 2022
53. ZHONG Y, Yu PB
    Decoding the Link Between Inflammation and Pulmonary Arterial Hypertension.
    Circulation. 2022;146:1023-1025.
    PubMed    
    
    
    
54. 
    Correction to: Nanoparticle Delivery of STAT3 Alleviates Pulmonary Hypertension in a Mouse Model of Alveolar Capillary Dysplasia.
    Circulation. 2022;146:e168.
    PubMed    
    
    
    August 2022
55. BRUSCA SB, Elinoff JM, Zou Y, Jang MK, et al
    Plasma Cell-Free DNA Predicts Survival and Maps Specific Sources of Injury in Pulmonary Arterial Hypertension.
    Circulation. 2022 Aug 25:101161CIRCULATIONAHA121056719.
    PubMed     Abstract available
    
    
    
56. YAKU A, Inagaki T, Asano R, Okazawa M, et al
    Regnase-1 Prevents Pulmonary Arterial Hypertension Through mRNA Degradation of Interleukin-6 and Platelet-Derived Growth Factor in Alveolar Macrophages.
    Circulation. 2022 Aug 23:101161CIRCULATIONAHA122059435.
    PubMed     Abstract available
    
    
    
57. RUFFENACH G, Medzikovic L, Aryan L, Li M, et al
    HNRNPA2B1: RNA-Binding Protein That Orchestrates Smooth Muscle Cell Phenotype in Pulmonary Arterial Hypertension.
    Circulation. 2022 Aug 22:101161CIRCULATIONAHA122059591.
    PubMed     Abstract available
    
    
    
58. STEFFES LC, Cheng P, Quertermous T, Kumar ME, et al
    von Willebrand Factor Is Produced Exclusively by Endothelium, Not Neointima, in Occlusive Vascular Lesions in Both Pulmonary Hypertension and Atherosclerosis.
    Circulation. 2022;146:429-431.
    PubMed    
    
    
    
59. JIN Q, Guan L, Zhou D
    Letter by Jin et al Regarding Article, "SPARC, A Novel Regulator of Vascular Cell Function in Pulmonary Hypertension".
    Circulation. 2022;146:e14-e15.
    PubMed    
    
    
    
60. VEITH C, Ghofrani HA, Weissmann N
    Response by Veith et al to Letter Regarding Article, "SPARC, A Novel Regulator of Vascular Cell Function in Pulmonary Hypertension".
    Circulation. 2022;146:e16-e17.
    PubMed    
    
    
    July 2022
61. BRITTAIN EL, Thenappan T, Huston JH, Agrawal V, et al
    Elucidating the Clinical Implications and Pathophysiology of Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction: A Call to Action: A Science Advisory From the American Heart Association.
    Circulation. 2022 Jul 11:101161CIR0000000000001079.
    PubMed     Abstract available
    
    
    
62. TREMBLAY E, Gosselin C, Mai V, Lajoie AC, et al
    Assessment of Clinical Worsening End Points as a Surrogate for Mortality in Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Circulation. 2022 Jul 8:101161CIRCULATIONAHA121058635.
    PubMed     Abstract available
    
    
    March 2022
63. STEWART RH, Cox CS Jr, Allen SJ, Laine GA, et al
    Myocardial Edema Provides a Link Between Pulmonary Arterial Hypertension and Pericardial Effusion.
    Circulation. 2022;145:793-795.
    PubMed    
    
    
    
64. LECHUGA-VIECO AV, Latorre-Pellicer A, Calvo E, Torroja C, et al
    Heteroplasmy of Wild Type Mitochondrial DNA Variants in Mice Causes Metabolic Heart Disease With Pulmonary Hypertension and Frailty.
    Circulation. 2022 Mar 3. doi: 10.1161/CIRCULATIONAHA.121.056286.
    PubMed     Abstract available
    
    

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