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	The Medical Article of the Year 2008: Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78. Free full-text

Pulmonary Hypertension

Free Subscription Articles published in Circulation Retrieve available abstracts of 57 articles: HTML format

Single Articles

June 2008
1. FARBER HW
   The status of pulmonary arterial hypertension in 2008.
   Circulation. 2008;117:2966-8.
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2. DILLER GP , van Eijl S, Okonko DO, Howard LS, et al
   Circulating Endothelial Progenitor Cells in Patients With Eisenmenger Syndrome and Idiopathic Pulmonary Arterial Hypertension.
   Circulation. 2008;.
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   May 2008
3. DEMPSIE Y , Morecroft I, Welsh DJ, Macritchie NA, et al
   Converging Evidence in Support of the Serotonin Hypothesis of Dexfenfluramine-Induced Pulmonary Hypertension With Novel Transgenic Mice.
   Circulation. 2008;.
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4. GALIE N , Olschewski H, Oudiz RJ, Torres F, et al
   Ambrisentan for the Treatment of Pulmonary Arterial Hypertension. Results of the Ambrisentan in Pulmonary Arterial Hypertension, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Efficacy (ARIES) Study 1 and 2.
   Circulation. 2008;.
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5. SHAH SJ , Thenappan T, Rich S, Tian L, et al
   Association of Serum Creatinine With Abnormal Hemodynamics and Mortality in Pulmonary Arterial Hypertension.
   Circulation. 2008;.
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   April 2008
6. FREDENBURGH LE , Liang OD, Macias AA, Polte TR, et al
   Absence of Cyclooxygenase-2 Exacerbates Hypoxia-Induced Pulmonary Hypertension and Enhances Contractility of Vascular Smooth Muscle Cells.
   Circulation. 2008;.
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   November 2007
7. BARTSCH P , Gibbs JS
   Effect of altitude on the heart and the lungs.
   Circulation. 2007;116:2191-202.
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8. SHAFIQ Q , Bashir R
   Images in cardiovascular medicine. ST-segment elevations secondary to electrical cardioversion.
   Circulation. 2007;116:e519-20.
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   September 2007
9. LEWIS GD , Shah R, Shahzad K, Camuso JM, et al
   Sildenafil Improves Exercise Capacity and Quality of Life in Patients With Systolic Heart Failure and Secondary Pulmonary Hypertension.
   Circulation. 2007;.
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10. ENDO J , Sano M, Fujita J, Hayashida K, et al
    Bone marrow derived cells are involved in the pathogenesis of cardiac hypertrophy in response to pressure overload.
    Circulation. 2007;116:1176-84.
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    August 2007
11. VERMEERSCH P , Buys E, Pokreisz P, Marsboom G, et al
    Soluble guanylate cyclase-alpha1 deficiency selectively inhibits the pulmonary vasodilator response to nitric oxide and increases the pulmonary vascular remodeling response to chronic hypoxia.
    Circulation. 2007;116:936-43.
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    May 2007
12. ZAKRZEWICZ A , Hecker M, Marsh LM, Kwapiszewska G, et al
    Receptor for Activated C-Kinase 1, a Novel Interaction Partner of Type II Bone Morphogenetic Protein Receptor, Regulates Smooth Muscle Cell Proliferation in Pulmonary Arterial Hypertension.
    Circulation. 2007;.
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    April 2007
13. SCHERMULY RT , Pullamsetti SS, Kwapiszewska G, Dumitrascu R, et al
    Phosphodiesterase 1 Upregulation in Pulmonary Arterial Hypertension. Target for Reverse-Remodeling Therapy.
    Circulation. 2007;.
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14. BONDERMAN D , Skoro-Sajer N, Jakowitsch J, Adlbrecht C, et al
    Predictors of Outcome in Chronic Thromboembolic Pulmonary Hypertension.
    Circulation. 2007;.
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    March 2007
15. MAGNE J , Mathieu P, Dumesnil JG, Tanne D, et al
    Impact of prosthesis-patient mismatch on survival after mitral valve replacement.
    Circulation. 2007;115:1417-25.
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16. PENALOZA D , Arias-Stella J
    The heart and pulmonary circulation at high altitudes: healthy highlanders and chronic mountain sickness.
    Circulation. 2007;115:1132-46.
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17. HUEZ S , Faoro V, Vachiery JL, Unger P, et al
    Images in cardiovascular medicine. High-altitude-induced right-heart failure.
    Circulation. 2007;115:e308-9.
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18. HANSMANN G , Wagner RA, Schellong S, de Jesus Perez VA, et al
    Pulmonary Arterial Hypertension Is Linked to Insulin Resistance and Reversed by Peroxisome Proliferator-Activated Receptor-{gamma} Activation.
    Circulation. 2007;.
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    February 2007
19. DILLER GP , Gatzoulis MA
    Pulmonary vascular disease in adults with congenital heart disease.
    Circulation. 2007;115:1039-50.
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20. SAID SI , Hamidi SA, Dickman KG, Szema AM, et al
    Moderate Pulmonary Arterial Hypertension in Male Mice Lacking the Vasoactive Intestinal Peptide Gene.
    Circulation. 2007;.
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    January 2007
21. SAHARA M , Sata M, Morita T, Nakamura K, et al
    Diverse Contribution of Bone Marrow-Derived Cells to Vascular Remodeling Associated With Pulmonary Arterial Hypertension and Arterial Neointimal Formation.
    Circulation. 2007;.
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    December 2006
22. WARNES CA
    Transposition of the great arteries.
    Circulation. 2006;114:2699-709.
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23. D'AVILA A , Rabischoffsky A, Saad E
    Images in cardiovascular medicine. Reverse Bernheim phenomenon as a cause of exercise-induced syncope.
    Circulation. 2006;114:e618-20.
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    October 2006
24. VOELKEL NF , Quaife RA, Leinwand LA, Barst RJ, et al
    Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure.
    Circulation. 2006;114:1883-91.
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25. SCHNEIDER DJ , Moore JW
    Patent ductus arteriosus.
    Circulation. 2006;114:1873-82.
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26. WEBB G , Gatzoulis MA
    Atrial septal defects in the adult: recent progress and overview.
    Circulation. 2006;114:1645-53.
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27. NEWMAN JH , Robbins IM
    Exercise training in pulmonary hypertension: implications for the evaluation of drug trials.
    Circulation. 2006;114:1448-9.
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    September 2006
28. TORJESEN I
    Pulmonary hypertension: deserving of attention.
    Circulation. 2006;114:f149-50.
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29. MCLAUGHLIN VV , McGoon MD
    Pulmonary arterial hypertension.
    Circulation. 2006;114:1417-31.
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30. RUBIN LJ
    Endothelin-1 and the pulmonary vascular response to altitude: a new therapeutic target?
    Circulation. 2006;114:1350-1.
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31. MODESTI PA , Vanni S, Morabito M, Modesti A, et al
    Role of endothelin-1 in exposure to high altitude: Acute Mountain Sickness and Endothelin-1 (ACME-1) study.
    Circulation. 2006;114:1410-6.
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32. MERELES D , Ehlken N, Kreuscher S, Ghofrani S, et al
    Exercise and Respiratory Training Improve Exercise Capacity and Quality of Life in Patients With Severe Chronic Pulmonary Hypertension.
    Circulation. 2006;.
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    August 2006
33. JASMIN JF , Mercier I, Dupuis J, Tanowitz HB, et al
    Short-term administration of a cell-permeable caveolin-1 peptide prevents the development of monocrotaline-induced pulmonary hypertension and right ventricular hypertrophy.
    Circulation. 2006;114:912-20.
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34. HSIEH PC , MacGillivray C, Gannon J, Cruz FU, et al
    Local controlled intramyocardial delivery of platelet-derived growth factor improves postinfarction ventricular function without pulmonary toxicity.
    Circulation. 2006;114:637-44.
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    July 2006
35. KANKI-HORIMOTO S , Horimoto H, Mieno S, Kishida K, et al
    Implantation of mesenchymal stem cells overexpressing endothelial nitric oxide synthase improves right ventricular impairments caused by pulmonary hypertension.
    Circulation. 2006;114.
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    June 2006
36. DIMOPOULOS K , Okonko DO, Diller GP, Broberg CS, et al
    Abnormal ventilatory response to exercise in adults with congenital heart disease relates to cyanosis and predicts survival.
    Circulation. 2006;113:2796-802.
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    May 2006
37. BONNET S , Michelakis ED, Porter CJ, Andrade-Navarro MA, et al
    An Abnormal Mitochondrial-Hypoxia Inducible Factor-1{alpha}-Kv Channel Pathway Disrupts Oxygen Sensing and Triggers Pulmonary Arterial Hypertension in Fawn Hooded Rats. Similarities to Human Pulmonary Arterial Hypertension.
    Circulation. 2006;.
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38. ELLIOTT CG , Glissmeyer EW, Havlena GT, Carlquist J, et al
    Relationship of BMPR2 Mutations to Vasoreactivity in Pulmonary Arterial Hypertension.
    Circulation. 2006;.
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39. ROSENHEK R , Rader F, Klaar U, Gabriel H, et al
    Outcome of Watchful Waiting in Asymptomatic Severe Mitral Regurgitation.
    Circulation. 2006;.
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    April 2006
40. HOEPER MM , Mayer E, Simonneau G, Rubin LJ, et al
    Chronic thromboembolic pulmonary hypertension.
    Circulation. 2006;113:2011-20.
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41. EDDAHIBI S , Guignabert C, Barlier-Mur AM, Dewachter L, et al
    Cross Talk Between Endothelial and Smooth Muscle Cells in Pulmonary Hypertension. Critical Role for Serotonin-Induced Smooth Muscle Hyperplasia.
    Circulation. 2006;.
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    March 2006
42. SATOH K , Kagaya Y, Nakano M, Ito Y, et al
    Important Role of Endogenous Erythropoietin System in Recruitment of Endothelial Progenitor Cells in Hypoxia-Induced Pulmonary Hypertension in Mice.
    Circulation. 2006;.
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    January 2006
43. DUMITRASCU R , Weissmann N, Ghofrani HA, Dony E, et al
    Activation of Soluble Guanylate Cyclase Reverses Experimental Pulmonary Hypertension and Vascular Remodeling.
    Circulation. 2006;.
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    December 2005
44. HSUE PY , Waters DD
    What a cardiologist needs to know about patients with human immunodeficiency virus infection.
    Circulation. 2005;112:3947-57.
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45. NTSEKHE M , Hakim J
    Impact of human immunodeficiency virus infection on cardiovascular disease in Africa.
    Circulation 2005;112:3602-7.
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    November 2005
46. SHEEHAN R , Perloff JK, Fishbein MC, Gjertson D, et al
    Pulmonary neovascularity: a distinctive radiographic finding in Eisenmenger syndrome.
    Circulation. 2005;112:2778-85.
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    October 2005
47. MCCANN GP , Beek AM, Vonk-Noordegraaf A, van Rossum AC, et al
    Delayed contrast-enhanced magnetic resonance imaging in pulmonary arterial hypertension.
    Circulation 2005;112:e268.
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    September 2005
48. OGAWA A , Nakamura K, Matsubara H, Fujio H, et al
    Prednisolone Inhibits Proliferation of Cultured Pulmonary Artery Smooth Muscle Cells of Patients With Idiopathic Pulmonary Arterial Hypertension.
    Circulation 2005;.
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    August 2005
49. GAYNOR SL , Maniar HS, Bloch JB, Steendijk P, et al
    Right atrial and ventricular adaptation to chronic right ventricular pressure overload.
    Circulation. 2005;112.
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50. KANG WC , Park CH, Chung WJ, Han SH, et al
    Images in cardiovascular medicine. Severe pulmonary artery stenosis caused by extrinsic compression of a calcified circular ring.
    Circulation 2005;112:e76-8.
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    July 2005
51. MERKLINGER SL , Jones PL, Martinez EC, Rabinovitch M, et al
    Epidermal growth factor receptor blockade mediates smooth muscle cell apoptosis and improves survival in rats with pulmonary hypertension.
    Circulation 2005;112:423-31.
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52. SONG Y , Jones JE, Beppu H, Keaney JF Jr, et al
    Increased Susceptibility to Pulmonary Hypertension in Heterozygous BMPR2-Mutant Mice.
    Circulation 2005;.
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    June 2005
53. HUMPL T , Reyes JT, Holtby H, Stephens D, et al
    Beneficial Effect of Oral Sildenafil Therapy on Childhood Pulmonary Arterial Hypertension. Twelve-Month Clinical Trial of a Single-Drug, Open-Label, Pilot Study.
    Circulation 2005;.
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54. SITBON O , Humbert M, Jais X, Ioos V, et al
    Long-Term Response to Calcium Channel Blockers in Idiopathic Pulmonary Arterial Hypertension.
    Circulation 2005;.
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    February 2005
55. MACHADO RD , James V, Southwood M, Harrison RE, et al
    Investigation of second genetic hits at the BMPR2 locus as a modulator of disease progression in familial pulmonary arterial hypertension.
    Circulation 2005;111:607-13.
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56. YUAN JX , Rubin LJ
    Pathogenesis of pulmonary arterial hypertension: the need for multiple hits.
    Circulation 2005;111:534-8.
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    August 2004
57. VELEZ-ROA S , Ciarka A, Najem B, Vachiery JL, et al
    Increased Sympathetic Nerve Activity in Pulmonary Artery Hypertension.
    Circulation 2004;.
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