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	Amedeo Prize 2008 The 21 Finalists

Prostate Cancer

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April 2008
1. BERTILACCIO MT , Grioni M, Sutherland BW, Degl'innocenti E, et al
   Vasculature-targeted tumor necrosis factor-alpha increases the therapeutic index of doxorubicin against prostate cancer.
   Prostate. 2008;.
   PubMed     Related articles    Abstract available
   
   
   
2. ABRIL J , de Heredia ML, Gonzalez L, Cleries R, et al
   Altered expression of 12S/MT-RNR1, MT-CO2/COX2, and MT-ATP6 mitochondrial genes in prostate cancer.
   Prostate. 2008;.
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3. GOSSELAAR C , Kranse R, Roobol MJ, Roemeling S, et al
   The interobserver variability of digital rectal examination in a large randomized trial for the screening of prostate cancer.
   Prostate. 2008;.
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4. WU Z , Gioeli D, Conaway M, Weber MJ, et al
   Restoration of PTEN expression alters the sensitivity of prostate cancer cells to EGFR inhibitors.
   Prostate. 2008;.
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5. MEHRAEIN-GHOMI F , Lee E, Church DR, Thompson TA, et al
   JunD mediates androgen-induced oxidative stress in androgen dependent LNCaP human prostate cancer cells.
   Prostate. 2008;.
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6. INOUE T , Leman ES, Yeater DB, Getzenberg RH, et al
   The potential role of purine-rich element binding protein (PUR) alpha as a novel treatment target for hormone-refractory prostate cancer.
   Prostate. 2008;.
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   March 2008
7. JIANG M , Li M, Fu X, Huang Y, et al
   Simultaneously detection of genomic and expression alterations in prostate cancer using cDNA microarray.
   Prostate. 2008;.
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8. TROYER DA , Tang Y, Bedolla R, Adhvaryu SG, et al
   Characterization of PacMetUT1, a recently isolated human prostate cancer cell line.
   Prostate. 2008;.
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9. HORIGUCHI A , Zheng R, Shen R, Nanus DM, et al
   Inactivation of the NF2 tumor suppressor protein merlin in DU145 prostate cancer cells.
   Prostate. 2008;.
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10. SUN J , Purcell L, Gao Z, Isaacs SD, et al
    Association between sequence variants at 17q12 and 17q24.3 and prostate cancer risk in European and African Americans.
    Prostate. 2008;.
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11. MORGAN TM , Pitts TE, Gross TS, Poliachik SL, et al
    RAD001 (Everolimus) inhibits growth of prostate cancer in the bone and the inhibitory effects are increased by combination with docetaxel and zoledronic acid.
    Prostate. 2008;.
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12. FESTUCCIA C , Gravina GL, Muzi P, Millimaggi D, et al
    Akt down-modulation induces apoptosis of human prostate cancer cells and synergizes with EGFR tyrosine kinase inhibitors.
    Prostate. 2008;.
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13. IGNATOSKI KM , Escara-Wilke JF, Dai JL, Lui A, et al
    RANKL inhibition is an effective adjuvant for docetaxel in a prostate cancer bone metastases model.
    Prostate. 2008;.
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14. RICCIARDELLI C , Jackson MW, Choong CS, Stahl J, et al
    Elevated levels of HER-2/neu and androgen receptor in clinically localized prostate cancer identifies metastatic potential.
    Prostate. 2008;.
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15. JIA L , Yu W, Wang P, Sanders BG, et al
    In vivo and in vitro studies of anticancer actions of alpha-TEA for human prostate cancer cells.
    Prostate. 2008;.
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16. WANG W , Rayburn ER, Hao M, Zhao Y, et al
    Experimental therapy of prostate cancer with novel natural product anti-cancer ginsenosides.
    Prostate. 2008;.
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17. GRAVINA GL , Festuccia C, Millimaggi D, Dolo V, et al
    Chronic azacitidine treatment results in differentiating effects, sensitizes against bicalutamide in androgen-independent prostate cancer cells.
    Prostate. 2008;.
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18. MACOSKA JA , Begley LA, Dunn RL, Siddiqui J, et al
    Pilot and feasibility study of serum chemokines as markers to distinguish prostatic disease in men with low total serum PSA.
    Prostate. 2008;68:442-52.
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19. MINELLI A , Bellezza I, Tucci A, Conte C, et al
    2-chloroadenosine modulates PAR-1 and IL-23 expression and enhances docetaxel effects on PC3 cells.
    Prostate. 2008;68:360-72.
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20. RUNDLE A , Neugut AI
    Obesity and screening PSA levels among men undergoing an annual physical exam.
    Prostate. 2008;68:373-80.
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21. PALMER J , Venkateswaran V, Fleshner NE, Klotz LH, et al
    The impact of diet and micronutrient supplements on the expression of neuroendocrine markers in murine Lady transgenic prostate.
    Prostate. 2008;68:345-53.
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    February 2008
22. CHO KS , Lee JS, Cho NH, Park K, et al
    Gene amplification and mutation analysis of epidermal growth factor receptor in hormone refractory prostate cancer.
    Prostate. 2008;.
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23. NEELEY YC , Arredouani MS, Hollenbeck B, Eng MH, et al
    Partially circumventing peripheral tolerance for oncogene-specific prostate cancer immunotherapy.
    Prostate. 2008;.
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24. GOODWIN AC , Jadallah S, Toubaji A, Lecksell K, et al
    Increased spermine oxidase expression in human prostate cancer and prostatic intraepithelial neoplasia tissues.
    Prostate. 2008;.
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25. ALLMEN EU , Koch M, Fritz G, Legler DF, et al
    V domain of RAGE interacts with AGEs on prostate carcinoma cells.
    Prostate. 2008;.
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26. D'ANTONIO JM , Ma C, Monzon FA, Pflug BR, et al
    Longitudinal analysis of androgen deprivation of prostate cancer cells identifies pathways to androgen independence.
    Prostate. 2008;.
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27. AGALLIU I , Suuriniemi M, Prokunina-Olsson L, Johanneson B, et al
    Evaluation of a variant in the transcription factor 7-like 2 (TCF7L2) gene and prostate cancer risk in a population-based study.
    Prostate. 2008;.
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28. CHOW L , Rezmann L, Imamura K, Wang L, et al
    Functional angiotensin II type 2 receptors inhibit growth factor signaling in LNCaP and PC3 prostate cancer cell lines.
    Prostate. 2008;.
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29. ANGELUCCI A , Muzi P, Cristiano L, Millimaggi D, et al
    Neuroendocrine transdifferentiation induced by VPA is mediated by PPARgamma activation and confers resistance to antiblastic therapy in prostate carcinoma.
    Prostate. 2008;.
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30. TISCHKOWITZ M , Sabbaghian N, Ray AM, Lange EM, et al
    Analysis of the gene coding for the BRCA2-Interacting protein PALB2 in hereditary prostate cancer.
    Prostate. 2008;.
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31. MABJEESH NJ , Shefler A, Amir S, Matzkin H, et al
    Potentiation of 2-Methoxyestradiol-Induced cytotoxicity by blocking endothelin A receptor in prostate cancer cells.
    Prostate. 2008;.
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32. BERRY LJ , Au GG, Barry RD, Shafren DR, et al
    Potent Oncolytic activity of human enteroviruses against human prostate cancer.
    Prostate. 2008;.
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33. MORIKAWA A , Varma V, Gillespie TW, Lyles RH, et al
    Counting alleles in single lesions of prostate tumors from ethnically diverse patients.
    Prostate. 2008;68:231-40.
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34. OLSSON M , Lindstrom S, Haggkvist B, Adami HO, et al
    The UGT2B17 gene deletion is not associated with prostate cancer risk.
    Prostate. 2008;.
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35. SERDA RE , Bisoffi M, Thompson TA, Ji M, et al
    1alpha,25-Dihydroxyvitamin D(3) down-regulates expression of prostate specific membrane antigen in prostate cancer cells.
    Prostate. 2008;.
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36. STROM SS , Yamamura Y, Flores-Sandoval FN, Pettaway CA, et al
    Prostate cancer in Mexican-Americans: Identification of risk factors.
    Prostate. 2008;.
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37. KUNDU SD , Lee C, Billips BK, Habermacher GM, et al
    The toll-like receptor pathway: a novel mechanism of infection-induced carcinogenesis of prostate epithelial cells.
    Prostate. 2008;68:223-9.
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38. MOORE ML , Teitell MA, Kim Y, Watabe T, et al
    Deletion of PSCA increases metastasis of TRAMP-induced prostate tumors without altering primary tumor formation.
    Prostate. 2008;68:139-51.
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39. VAN WIJNGAARDEN E , Singer EA, Palapattu GS
    Prostate-specific antigen levels in relation to cadmium exposure and zinc intake: results from the 2001-2002 National Health and Nutrition Examination Survey.
    Prostate. 2008;68:122-8.
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    January 2008
40. PIENTA KJ , Abate-Shen C, Agus DB, Attar RM, et al
    The current state of preclinical prostate cancer animal models.
    Prostate. 2008;.
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41. SUN J , Lange EM, Isaacs SD, Liu W, et al
    Chromosome 8q24 risk variants in hereditary and non-hereditary prostate cancer patients.
    Prostate. 2008;.
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42. SERKOVA NJ , Gamito EJ, Jones RH, O'Donnell C, et al
    The metabolites citrate, myo-inositol, and spermine are potential age-independent markers of prostate cancer in human expressed prostatic secretions.
    Prostate. 2008;.
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43. GREGORAKIS AK , Stefanakis S, Malovrouvas D, Petraki K, et al
    Total and free PSA kinetics in patients without prostate cancer undergoing radical cystoprostatectomy.
    Prostate. 2008;.
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44. AITCHISON AA , Veerakumarasivam A, Vias M, Kumar R, et al
    Promoter methylation correlates with reduced Smad4 expression in advanced prostate cancer.
    Prostate. 2008;.
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45. MU Z , Hachem P, Hensley H, Stoyanova R, et al
    Antisense MDM2 enhances the response of androgen insensitive human prostate cancer cells to androgen deprivation in vitro and in vivo.
    Prostate. 2008;.
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46. KAUSHAL A , Myers SA, Dong Y, Lai J, et al
    A novel transcript from the KLKP1 gene is androgen regulated, down-regulated during prostate cancer progression and encodes the first non-serine protease identified from the human kallikrein gene locus.
    Prostate. 2008;.
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47. DANFORTH KN , Rodriguez C, Hayes RB, Sakoda LC, et al
    TNF polymorphisms and prostate cancer risk.
    Prostate. 2008;.
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48. SUN A , Tang J, Hong Y, Song J, et al
    Androgen receptor-dependent regulation of Bcl-xL expression: Implication in prostate cancer progression.
    Prostate. 2008;.
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49. LAI CL , van den Ham R, van Leenders G, van der Lugt J, et al
    Histopathological and immunohistochemical characterization of canine prostate cancer.
    Prostate. 2008;.
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50. SROKA IC , McDaniel K, Nagle RB, Bowden GT, et al
    Differential localization of MT1-MMP in human prostate cancer tissue: Role of IGF-1R in MT1-MMP expression.
    Prostate. 2008;.
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51. JIA L , Yu W, Wang P, Li J, et al
    Critical roles for JNK, c-Jun, and Fas/FasL-Signaling in vitamin E analog-induced apoptosis in human prostate cancer cells.
    Prostate. 2008;.
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52. MIZUMACHI T , Muskhelishvili L, Naito A, Furusawa J, et al
    Increased distributional variance of mitochondrial DNA content associated with prostate cancer cells as compared with normal prostate cells.
    Prostate. 2008;.
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53. LIU JW , Nagpal JK, Jeronimo C, Lee JE, et al
    Hypermethylation of MCAM gene is associated with advanced tumor stage in prostate cancer.
    Prostate. 2008;.
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54. SHEA PR , Ishwad CS, Bunker CH, Patrick AL, et al
    RNASEL and RNASEL-inhibitor variation and prostate cancer risk in Afro-Caribbeans.
    Prostate. 2008;.
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55. NARITA S , Tsuchiya N, Saito M, Inoue T, et al
    Candidate genes involved in enhanced growth of human prostate cancer under high fat feeding identified by microarray analysis.
    Prostate. 2008;.
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56. ARMSTRONG AP , Miller RE, Jones JC, Zhang J, et al
    RANKL acts directly on RANK-expressing prostate tumor cells and mediates migration and expression of tumor metastasis genes.
    Prostate. 2008;68:92-104.
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57. GUPTA A , Wang Y, Browne C, Kim S, et al
    Neuroendocrine differentiation in the 12T-10 transgenic prostate mouse model mimics endocrine differentiation of pancreatic beta cells.
    Prostate. 2008;68:50-60.
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58. LOCKE JA , Wasan KM, Nelson CC, Guns ES, et al
    Androgen-mediated cholesterol metabolism in LNCaP and PC-3 cell lines is regulated through two different isoforms of acyl-coenzyme A:Cholesterol Acyltransferase (ACAT).
    Prostate. 2008;68:20-33.
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    December 2007
59. ZHU ML , Partin JV, Bruckheimer EM, Strup SE, et al
    TGF-beta signaling and androgen receptor status determine apoptotic cross-talk in human prostate cancer cells.
    Prostate. 2007;.
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60. SARMA AV , Dunn RL, Lange LA, Ray A, et al
    Genetic polymorphisms in CYP17, CYP3A4, CYP19A1, SRD5A2, IGF-1, and IGFBP-3 and prostate cancer risk in African-American men: The Flint Men's Health Study.
    Prostate. 2007;.
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61. SFANOS KS , Sauvageot J, Fedor HL, Dick JD, et al
    A molecular analysis of prokaryotic and viral DNA sequences in prostate tissue from patients with prostate cancer indicates the presence of multiple and diverse microorganisms.
    Prostate. 2007;.
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62. SHAIDA N , Launchbury R, Boddy JL, Jones C, et al
    Expression of BNIP3 correlates with hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha and the androgen receptor in prostate cancer and is regulated directly by hypoxia but not androgens in cell lines.
    Prostate. 2007;.
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63. LANGSENLEHNER T , Langsenlehner U, Renner W, Kapp KS, et al
    The Glu228Ala polymorphism in the ligand binding domain of death receptor 4 is associated with increased risk for prostate cancer metastases.
    Prostate. 2007;.
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64. HELLSTEN R , Johansson M, Dahlman A, Dizeyi N, et al
    Galiellalactone is a novel therapeutic candidate against hormone-refractory prostate cancer expressing activated Stat3.
    Prostate. 2007;.
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65. SONG Y , Tangen C, Goodman P, Parnes HL, et al
    Finasteride, prostate cancer, and weight gain: Evidence for genetic or environmental factors that affect cancer outcomes during finasteride treatment.
    Prostate. 2007;.
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66. BRYANT RJ , Winder SJ, Cross SS, Hamdy FC, et al
    The polycomb group protein EZH2 regulates actin polymerization in human prostate cancer cells.
    Prostate. 2007;.
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67. WALTON TJ , Li G, Seth R, McArdle SE, et al
    DNA demethylation and histone deacetylation inhibition co-operate to re-express estrogen receptor beta and induce apoptosis in prostate cancer cell-lines.
    Prostate. 2007;.
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68. MAKAROV DV , Marlow C, Epstein JI, Miller MC, et al
    Using nuclear morphometry to predict the need for treatment among men with low grade, low stage prostate cancer enrolled in a program of expectant management with curative intent.
    Prostate. 2007;.
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69. ZHIGANG Z , Wenlu S
    The association of prostate stem cell antigen (PSCA) mRNA expression and subsequent prostate cancer risk in men with benign prostatic hyperplasia following transurethral resection of the prostate.
    Prostate. 2007;.
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70. GUSTAVSSON H , Jennbacken K, Welen K, Damber JE, et al
    Altered expression of genes regulating angiogenesis in experimental androgen-independent prostate cancer.
    Prostate. 2007;.
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71. THORPE JA , Christian PA, Schwarze SR
    Proteasome inhibition blocks caspase-8 degradation and sensitizes prostate cancer cells to death receptor-mediated apoptosis.
    Prostate. 2007;.
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72. BETHEL CR , Bieberich CJ
    Loss of Nkx3.1 expression in the transgenic adenocarcinoma of mouse prostate model.
    Prostate. 2007;67:1740-50.
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73. QIAO Y , Zhang ZK, Cai LQ, Tan C, et al
    17alpha-estradiol inhibits LAPC-4 prostatic tumor cell proliferation in cell cultures and tumor growth in xenograft animals.
    Prostate. 2007;67:1719-28.
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    November 2007
74. MEHROTRA J , Varde S, Wang H, Chiu H, et al
    Quantitative, spatial resolution of the epigenetic field effect in prostate cancer.
    Prostate. 2007;.
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75. WOLF P , Alt K, Buhler P, Katzenwadel A, et al
    Anti-PSMA immunotoxin as novel treatment for prostate cancer? High and specific antitumor activity on human prostate xenograft tumors in SCID mice.
    Prostate. 2007;.
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76. CHIU FL , Lin JK
    Downregulation of androgen receptor expression by luteolin causes inhibition of cell proliferation and induction of apoptosis in human prostate cancer cells and xenografts.
    Prostate. 2007;.
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77. MERSEBURGER AS , Kramer MW, Hennenlotter J, Simon P, et al
    Involvement of decreased Galectin-3 expression in the pathogenesis and progression of prostate cancer.
    Prostate. 2007;.
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78. SAHA B , Arase A, Imam SS, Tsao-Wei D, et al
    Overexpression of E-cadherin and beta-Catenin proteins in metastatic prostate cancer cells in bone.
    Prostate. 2007;.
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79. LEE SO , Pinder E, Chun JY, Lou W, et al
    Interleukin-4 stimulates androgen-independent growth in LNCaP human prostate cancer cells.
    Prostate. 2007;.
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80. HIGUCHI T , Nakamura M, Shimada K, Ishida E, et al
    HRK inactivation associated with promoter methylation and LOH in prostate cancer.
    Prostate. 2007;.
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81. ELLINGER J , Haan K, Heukamp LC, Kahl P, et al
    CpG Island hypermethylation in cell-free serum DNA identifies patients with localized prostate cancer.
    Prostate. 2007;.
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82. FREEDLAND SJ , Mavropoulos J, Wang A, Darshan M, et al
    Carbohydrate restriction, prostate cancer growth, and the insulin-like growth factor axis.
    Prostate. 2007;.
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83. LEROUX ME , Auzenne E, Evans R, Hail N Jr, et al
    Sphingolipids and the sphingosine kinase inhibitor, SKI II, induce BCL-2-independent apoptosis in human prostatic adenocarcinoma cells.
    Prostate. 2007;67:1699-717.
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84. GARCIA FU , Haber MM, Chen X
    Prostatic basal cells in the peripheral and transitional zones: zonal variation in morphology and in immunophenotype.
    Prostate. 2007;67:1686-92.
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    October 2007
85. EBELT K , Babaryka G, Figel AM, Pohla H, et al
    Dominance of CD4(+) lymphocytic infiltrates with disturbed effector cell characteristics in the tumor microenvironment of prostate carcinoma.
    Prostate. 2007;.
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86. WANG D , Lu S, Dong Z
    Regulation of TGF-beta1 gene transcription in human prostate cancer cells by nitric oxide.
    Prostate. 2007;.
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87. TARAROVA ND , Narizhneva N, Krivokrisenko V, Gudkov AV, et al
    Prostate cancer cells tolerate a narrow range of androgen receptor expression and activity.
    Prostate. 2007;.
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88. LEIBLICH A , Cross SS, Catto JW, Pesce G, et al
    Human prostate cancer cells express neuroendocrine cell markers PGP 9.5 and chromogranin A.
    Prostate. 2007;.
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89. CAO KY , Mao XP, Wang DH, Xu L, et al
    High expression of PSM-E correlated with tumor grade in prostate cancer: A new alternatively spliced variant of prostate-specific membrane antigen.
    Prostate. 2007;.
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90. DUBOVSKY JA , McNeel DG
    Inducible expression of a prostate cancer-testis antigen, SSX-2, following treatment with a DNA methylation inhibitor.
    Prostate. 2007;.
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91. WLAZLINSKI A , Engers R, Hoffmann MJ, Hader C, et al
    Downregulation of several fibulin genes in prostate cancer.
    Prostate. 2007;.
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92. PROWALD A , Cronauer MV, von Klot C, Eilers T, et al
    Modulation of beta-catenin-mediated TCF-signalling in prostate cancer cell lines by wild-type and mutant p53.
    Prostate. 2007;.
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93. BIGLER D , Gioeli D, Conaway MR, Weber MJ, et al
    Rap2 regulates androgen sensitivity in human prostate cancer cells.
    Prostate. 2007;67:1590-9.
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94. PARK SE , Park JW, Cho YS, Ryu JH, et al
    HIF-1alpha promotes survival of prostate cells at a high zinc environment.
    Prostate. 2007;67:1514-23.
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    September 2007
95. OLSON BM , McNeel DG
    Antibody and T-cell responses specific for the androgen receptor in patients with prostate cancer.
    Prostate. 2007;.
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96. MAO S , Daliani DD, Wang X, Thall PF, et al
    Employing the treatment-free interval of intermittent androgen ablation to screen candidate prostate cancer therapies.
    Prostate. 2007;67:1677-1685.
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97. PARIS PL , Sridharan S, Scheffer A, Tsalenko A, et al
    High resolution oligonucleotide CGH using DNA from archived prostate tissue.
    Prostate. 2007;67:1447-55.
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98. MEMARI N , Diamandis EP, Earle T, Campbell A, et al
    Human kallikrein-related peptidase 12: antibody generation and immunohistochemical localization in prostatic tissues.
    Prostate. 2007;67:1465-74.
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99. OLSSON M , Gustafsson O, Skogastierna C, Tolf A, et al
    Regulation and expression of human CYP7B1 in prostate: overexpression of CYP7B1 during progression of prostatic adenocarcinoma.
    Prostate. 2007;67:1439-46.
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100. BROWN MD , Gilmore PE, Hart CA, Samuel JD, et al
     Characterization of benign and malignant prostate epithelial Hoechst 33342 side populations.
     Prostate. 2007;67:1384-96.
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101. PRESCOTT J , Jariwala U, Jia L, Cogan JP, et al
     Androgen receptor-mediated repression of novel target genes.
     Prostate. 2007;67:1371-83.
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102. JOHANSSON A , Jones J, Pietras K, Kilter S, et al
     A stroma targeted therapy enhances castration effects in a transplantable rat prostate cancer model.
     Prostate. 2007;.
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103. NESLUND-DUDAS C , Bock CH, Monaghan K, Nock NL, et al
     SRD5A2 and HSD3B2 polymorphisms are associated with prostate cancer risk and aggressiveness.
     Prostate. 2007;.
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104. ZHANG AL , Russell PJ, Knittel T, Milross C, et al
     Paclitaxel enhanced radiation sensitization for the suppression of human prostate cancer tumor growth via a p53 independent pathway.
     Prostate. 2007;.
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105. GILL C , Walsh SE, Morrissey C, Fitzpatrick JM, et al
     Resveratrol sensitizes androgen independent prostate cancer cells to death-receptor mediated apoptosis through multiple mechanisms.
     Prostate. 2007;.
     PubMed     Related articles    Abstract available
     
     
     
106. CHOO R , Danjoux C, Morton G, Szumacher E, et al
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