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Alzheimer's Disease

Free Subscription Articles published in Exp Neurol Retrieve available abstracts of 71 articles: HTML format

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November 2025
1. ALTINDAG F, Bayir MH, Alhalboosi JKI, Yildizhan K, et al
   Syringic acid mitigates scopolamine-induced cognitive impairment by regulating PSD-95 and GSK-3beta and by preventing neurodegeneration in an Alzheimer-like rat model.
   Exp Neurol. 2025 Nov 17:115556. doi: 10.1016/j.expneurol.2025.115556.
   PubMed     Abstract available
   
   
   
2. HEATH AM, Mojabi FS, Kraybill EP, Beard C, et al
   Comparison of treatment schedules on cognitive effects of rTMS in the 3xTg-AD model of Alzheimer's disease.
   Exp Neurol. 2025;396:115551.
   PubMed     Abstract available
   
   
   
3. YAO M, Li Z, Lin Y, Cai H, et al
   Hyperbaric oxygen therapy ameliorates Alzheimer's disease pathology by restoration of mitophagy and suppressing neuroinflammation in 5xFAD mice.
   Exp Neurol. 2025 Nov 4:115534. doi: 10.1016/j.expneurol.2025.115534.
   PubMed     Abstract available
   
   
   October 2025
4. ZHENG M, Zhang Q, Siebert HC, Loers G, et al
   Semaglutide attenuates Alzheimer's disease model progression by targeting microglial NLRP3 inflammasome-mediated neuroinflammation and ferroptosis.
   Exp Neurol. 2025 Oct 29:115537. doi: 10.1016/j.expneurol.2025.115537.
   PubMed     Abstract available
   
   
   
5. YOUSEFI A, Karimani F, Delphi L, Ghahfarokhi MR, et al
   Modulation of the mediodorsal thalamus nitric oxide system ameliorated amnesia and medial prefrontal abnormal network activity in a streptozotocin-induced rat model of Alzheimer's disease.
   Exp Neurol. 2025 Oct 22:115524. doi: 10.1016/j.expneurol.2025.115524.
   PubMed     Abstract available
   
   
   
6. VRBJAR N, Radosinska D, Radosinska J
   The involvement of Na,K-ATPase enzyme in the development of Alzheimer's disease.
   Exp Neurol. 2025 Oct 21:115526. doi: 10.1016/j.expneurol.2025.115526.
   PubMed     Abstract available
   
   
   
7. KIM D, Shim K, Kim J, Ko G, et al
   Potential anti-amyloid beta oligomerization effects of PD166793 in Alzheimer's disease.
   Exp Neurol. 2025 Oct 13:115504. doi: 10.1016/j.expneurol.2025.115504.
   PubMed     Abstract available
   
   
   
8. PANTIYA P, Chattipakorn N, Chattipakorn SC
   Exploring the role of CD147 in cerebrovascular and Alzheimer's pathologies: Insights into mechanisms and interventions.
   Exp Neurol. 2025;395:115498.
   PubMed     Abstract available
   
   
   
9. GENG D, Yan Y, Liu A, Zheng W, et al
   Experimental and computational study of 40?Hz low-field magnetic stimulation modulating neural activity and pathology in a mouse model of Alzheimer's disease.
   Exp Neurol. 2025 Oct 6:115494. doi: 10.1016/j.expneurol.2025.115494.
   PubMed     Abstract available
   
   
   
10. ZHANG M, Hai S, Gao X, Cui Z, et al
    MYT1L promotes autophagy to ameliorate amyloid-beta pathology and cognitive deficits in Alzheimer's disease via Notch signaling pathway.
    Exp Neurol. 2025 Oct 6:115492. doi: 10.1016/j.expneurol.2025.115492.
    PubMed     Abstract available
    
    
    
11. LI S, Zheng F, Liu S, Wu R, et al
    Physical exercise protects neurons from energy deficit and improves cognitive function by upregulating astrocytic Slc2a1 in Alzheimer's disease.
    Exp Neurol. 2025 Oct 6:115493. doi: 10.1016/j.expneurol.2025.115493.
    PubMed     Abstract available
    
    
    
12. CHEN G, Zhang J, Dong A, Xiao L, et al
    AXL-mediate GEF-H1 phosphorylation was involved in microglia synapse phagocytosis in 5xFAD mice.
    Exp Neurol. 2025;392:115327.
    PubMed     Abstract available
    
    
    September 2025
13. ONO K, Noguchi-Shinohara M, Yoshita M, Naiki H, et al
    Retraction Notice to "Cerebrospinal fluid of Alzheimer's disease and dementia with Lewy bodies patients enhances -synuclein fibril formation in vitro" [Experimental Neurology 203 (2007) 579-583].
    Exp Neurol. 2025 Sep 10:115456. doi: 10.1016/j.expneurol.2025.115456.
    PubMed    
    
    
    August 2025
14. SU WS, Wu MT, Cheng IH, Yang FY, et al
    Low-intensity pulsed ultrasound enhances microglial-mediated Abeta clearance and synaptic preservation in an APP transgenic mouse model of Alzheimer's disease.
    Exp Neurol. 2025 Aug 12:115420. doi: 10.1016/j.expneurol.2025.115420.
    PubMed     Abstract available
    
    
    
15. KAYE S, Gold A, Lin D, Chen M, et al
    Hypercholesterolemia drives microglial dysfunction and weakens response to amyloid plaques.
    Exp Neurol. 2025;390:115272.
    PubMed     Abstract available
    
    
    July 2025
16. AZMAL M, Paul JK, Prima FS, Haque ANMSNB, et al
    Microglial dysfunction in Alzheimer's disease: Mechanisms, emerging therapies, and future directions.
    Exp Neurol. 2025;392:115374.
    PubMed     Abstract available
    
    
    
17. ALVES RL, Goncalves A, Voytyuk I, Harrison DC, et al
    Behaviour profile characterization of PS19 and rTg4510 tauopathy mouse models: A systematic review and a meta-analysis.
    Exp Neurol. 2025;389:115234.
    PubMed     Abstract available
    
    
    June 2025
18. FRENCH AR, Christian-Hinman CA
    Aromatase inhibition modulates intrinsic properties and excitability of hippocampal CA1 pyramidal cells in the APP/PS1 mouse model of Alzheimer's disease.
    Exp Neurol. 2025 Jun 30:115365. doi: 10.1016/j.expneurol.2025.115365.
    PubMed     Abstract available
    
    
    
19. HUNG WC, Sun WC, Su TC, Lee YJ, et al
    FGFR1 agonists alleviate pathology and cognitive impairment in an Alzheimer's disease mouse model.
    Exp Neurol. 2025 Jun 23:115357. doi: 10.1016/j.expneurol.2025.115357.
    PubMed     Abstract available
    
    
    
20. PENG XQ, Guo HS, Zhang X, Wu XY, et al
    TREM2 promotes hippocampal neurogenesis through regulating microglial M2 polarization in APP/PS1 mice.
    Exp Neurol. 2025;388:115205.
    PubMed     Abstract available
    
    
    May 2025
21. VIJAYAN V, Siddique IA, Gupta S, Chopra EM, et al
    Osteocalcin modulates Abeta42 aggregation to aid in amyloid reduction in mouse models of Alzheimer's disease.
    Exp Neurol. 2025 May 27:115322. doi: 10.1016/j.expneurol.2025.115322.
    PubMed     Abstract available
    
    
    
22. HE Q, Jiang L, Chao FL, Zhou CN, et al
    The role of LINGO-1 in regulating CB1R/TrkB signalling and GABAergic interneurons in Alzheimer's disease pathogenesis.
    Exp Neurol. 2025 May 27:115319. doi: 10.1016/j.expneurol.2025.115319.
    PubMed     Abstract available
    
    
    April 2025
23. SIM AY, Kim JY, Lee YH, Lee JE, et al
    Neuroprotective roles of SGLT2 and DPP4 inhibitors: Modulating ketone metabolism and suppressing NLRP3 inflammasome in T2D induced Alzheimer's disease.
    Exp Neurol. 2025 Apr 26:115271. doi: 10.1016/j.expneurol.2025.115271.
    PubMed     Abstract available
    
    
    
24. KERR NA, Bramlett HM, Sanchez-Molano J, Higueras AF, et al
    Stool-derived extracellular vesicles increase inflammasome signaling and regulate the gut-brain axis after stroke in Alzheimer's disease transgenic mice.
    Exp Neurol. 2025;390:115269.
    PubMed     Abstract available
    
    
    
25. REN J, Wang Y, Wang Y, Zhang Y, et al
    Dynamic changes of hippocampal dendritic spines in Alzheimer's disease mice among the different stages.
    Exp Neurol. 2025 Apr 15:115266. doi: 10.1016/j.expneurol.2025.115266.
    PubMed     Abstract available
    
    
    
26. ROZEBOOM A, Broekaart DWM, Anink JJ, Boonkamp L, et al
    Cellular expression of low-density lipoprotein receptor-related protein 1 and amyloid beta deposition in human and rat epileptogenic brain.
    Exp Neurol. 2025;386:115149.
    PubMed     Abstract available
    
    
    March 2025
27. LIU TT, Yang X, Lei HP, Hu YT, et al
    Gastrodin alleviates Abeta(25-35)-induced glycolytic dysfunction via activating PI3K/AKT/BACH1 signaling in Alzheimer's disease models.
    Exp Neurol. 2025 Mar 22:115225. doi: 10.1016/j.expneurol.2025.115225.
    PubMed     Abstract available
    
    
    
28. ALTUN S, Ozdemir S, Arslan H, Kiliclioglu M, et al
    Impact of long-term deltamethrin exposure on Alzheimer's-related neurodegeneration in rats.
    Exp Neurol. 2025;388:115223.
    PubMed     Abstract available
    
    
    
29. WANG A, Zhang F, Zhang W, Gong J, et al
    PPM1D ameliorates Alzheimer's disease by promoting mitophagy.
    Exp Neurol. 2025 Mar 14:115218. doi: 10.1016/j.expneurol.2025.115218.
    PubMed     Abstract available
    
    
    
30. DA SILVA EA, Faber J, Penitente AR, Fernandes J, et al
    Effects of resistance exercise on behavioral and molecular changes in transgenic female mice for Alzheimer's disease in early and advanced stages.
    Exp Neurol. 2025;388:115217.
    PubMed     Abstract available
    
    
    February 2025
31. CARTER SKR, Tipton RK, Forman CM, Mosher AP, et al
    Glutamate stress in the caudal nucleus tractus solitarii (nTS): Impact on respiratory function and synaptic signaling in an Alzheimer's disease model.
    Exp Neurol. 2025;387:115190.
    PubMed     Abstract available
    
    
    
32. RODRIGUEZ-LOPEZ A, Esteban D, Dominguez-Romero AN, Gevorkian G, et al
    Tg-SwDI transgenic mice: A suitable model for Alzheimer's disease and cerebral amyloid angiopathy basic research and preclinical studies.
    Exp Neurol. 2025;387:115189.
    PubMed     Abstract available
    
    
    January 2025
33. YANG MX, Wang ZR, Zhang YL, Zhang ZN, et al
    Albumin antagonizes Alzheimer's disease-related Tau pathology and enhances cognitive performance by inhibiting aberrant Tau aggregation.
    Exp Neurol. 2025 Jan 19:115155. doi: 10.1016/j.expneurol.2025.115155.
    PubMed     Abstract available
    
    
    
34. LIU S, Liu X, Ke M, Wang J, et al
    Sleep fragmentation impairs cognitive function and exacerbates Alzheimer's disease-related pathology in a mouse model by disrupting mitochondrial biogenesis.
    Exp Neurol. 2025;386:115153.
    PubMed     Abstract available
    
    
    
35. LI M, Mo Y, Yu Q, Anayyat U, et al
    Rotating magnetic field improves cognitive and memory impairments in APP/PS1 mice by activating autophagy and inhibiting the PI3K/AKT/mTOR signaling pathway.
    Exp Neurol. 2025;383:115029.
    PubMed     Abstract available
    
    
    December 2024
36. KAUR R, Pandey S, Gupta S, Singh J, et al
    Harnessing the potential of long non-coding RNAs in the pathophysiology of Alzheimer's disease.
    Exp Neurol. 2024;385:115134.
    PubMed     Abstract available
    
    
    
37. FRANKLIN Z, Hull C, Delibegovic M, Platt B, et al
    Pharmacological PTP1B inhibition rescues motor learning, neuroinflammation, and hyperglycaemia in a mouse model of Alzheimer's disease.
    Exp Neurol. 2024;385:115115.
    PubMed     Abstract available
    
    
    November 2024
38. WANG Y, Wu W, Zeng F, Meng X, et al
    The role of kynurenine pathway metabolism mediated by exercise in the microbial-gut-brain axis in Alzheimer's disease.
    Exp Neurol. 2024;384:115070.
    PubMed     Abstract available
    
    
    
39. EL-DESOUKY S, Abdel-Halim M, Fathalla RK, Abadi AH, et al
    A novel phosphodiesterase 5 inhibitor, RF26, improves memory impairment and ameliorates tau aggregation and neuroinflammation in the P301S tauopathy mouse model of Alzheimer's disease.
    Exp Neurol. 2024;384:115058.
    PubMed     Abstract available
    
    
    
40. MERINO-SERRAIS P, Soria JM, Arrabal CA, Ortigado-Lopez A, et al
    Protein tau phosphorylation in the proline rich region and its implication in the progression of Alzheimer's disease.
    Exp Neurol. 2024 Nov 8:115049. doi: 10.1016/j.expneurol.2024.115049.
    PubMed     Abstract available
    
    
    October 2024
41. DHIMAN N, Deshwal S, Rishi V, Singhal N, et al
    Zebrafish as a model organism to study sporadic Alzheimer's disease: Behavioural, biochemical and histological validation.
    Exp Neurol. 2024 Oct 25:115034. doi: 10.1016/j.expneurol.2024.115034.
    PubMed     Abstract available
    
    
    
42. ZHENG F, Dong T, Chen Y, Wang L, et al
    Border-associated macrophages: From physiology to therapeutic targets in Alzheimer's disease.
    Exp Neurol. 2024;383:115021.
    PubMed     Abstract available
    
    
    
43. WANG X, Wang Q, Wang X, Zhao H, et al
    Early intervention using long-term rhythmic pulsed magnetic stimulation alleviates cognitive decline in a 5xFAD mouse model of Alzheimer's disease.
    Exp Neurol. 2024 Oct 15:115002. doi: 10.1016/j.expneurol.2024.115002.
    PubMed     Abstract available
    
    
    September 2024
44. BALE LK, West SA, Gades NM, Baker DJ, et al
    Gene deletion of Pregnancy-associated Plasma Protein-A (PAPP-A) improves pathology and cognition in an Alzheimer's disease mouse model.
    Exp Neurol. 2024;382:114976.
    PubMed     Abstract available
    
    
    August 2024
45. YE Y, Fu C, Li Y, Sun J, et al
    Alternate-day fasting improves cognitive and brain energy deficits by promoting ketone metabolism in the 3xTg mouse model of Alzheimer's disease.
    Exp Neurol. 2024 Aug 12:114920. doi: 10.1016/j.expneurol.2024.114920.
    PubMed     Abstract available
    
    
    July 2024
46. BERETTI F, Gatti M, Ricchi F, Lipani F, et al
    Neurotoxic effects of coronavirus: Potential implications in Alzheimer's onset and progression.
    Exp Neurol. 2024 Jul 30:114908. doi: 10.1016/j.expneurol.2024.114908.
    PubMed     Abstract available
    
    
    
47. ZHAO Y, He C, Hu S, Ni H, et al
    Anti-oxidative stress and cognitive improvement of a semi-synthetic isoorientin-based GSK-3beta inhibitor in rat pheochromocytoma cell PC12 and scopolamine-induced AD model mice via AKT/GSK-3beta/Nrf2 pathway.
    Exp Neurol. 2024 Jul 10:114881. doi: 10.1016/j.expneurol.2024.114881.
    PubMed     Abstract available
    
    
    
48. LI CL, Zhou GF, Xie XY, Wang L, et al
    STAU1 exhibits a dual function by promoting amyloidogenesis and tau phosphorylation in cultured cells.
    Exp Neurol. 2024;377:114805.
    PubMed     Abstract available
    
    
    May 2024
49. HUANG XY, Xue LL, Ma RF, Shi JS, et al
    Inhibition of CXCR4: A perspective on miracle fruit seed for Alzheimer's disease treatment.
    Exp Neurol. 2024 May 29:114841. doi: 10.1016/j.expneurol.2024.114841.
    PubMed     Abstract available
    
    
    
50. EL-ARABY RE, Wasif K, Johnson R, Tu Q, et al
    Establishment of a novel cellular model for Alzheimer's disease in vitro studies.
    Exp Neurol. 2024 May 22:114820. doi: 10.1016/j.expneurol.2024.114820.
    PubMed     Abstract available
    
    
    
51. ZHANG Y, Mu BR, Ran Z, Zhu T, et al
    Pericytes in Alzheimer's disease: Key players and therapeutic targets.
    Exp Neurol. 2024 May 20:114825. doi: 10.1016/j.expneurol.2024.114825.
    PubMed     Abstract available
    
    
    
52. BARATI N, Shojaeian A, Ramezani M, Kalhori F, et al
    Investigating the effect of parasites (toxoplasma gondii RH strain, Leishmania major (MRHO/IR/75/ER), and hydatid cyst) antigens on Alzheimer's disease: An in vivo evaluation.
    Exp Neurol. 2024;377:114813.
    PubMed     Abstract available
    
    
    March 2024
53. ZHUGE F, Zheng L, Pan Y, Ni L, et al
    DPP-4 inhibition by linagliptin ameliorates age-related mild cognitive impairment by regulating microglia polarization in mice.
    Exp Neurol. 2024;373:114689.
    PubMed     Abstract available
    
    
    
54. ZUO Y, Liu HT, Lin LB, Yue RZ, et al
    A new metal ion chelator attenuates human tau accumulation-induced neurodegeneration and memory deficits in mice.
    Exp Neurol. 2024;373:114657.
    PubMed     Abstract available
    
    
    February 2024
55. ESHANI M, Anupam R, Raj SA, Ashish J, et al
    To evaluate the effect of endothelin receptor agonist IRL-1620 alone and in combination with donepezil in modulating neurodegeneration elicited by amyloid-beta in rats.
    Exp Neurol. 2024 Feb 9:114720. doi: 10.1016/j.expneurol.2024.114720.
    PubMed     Abstract available
    
    
    January 2024
56. XU M, Li J, Xia L, Du Y, et al
    PCSK6 exacerbates Alzheimer's disease pathogenesis by promoting MT5-MMP maturation.
    Exp Neurol. 2024 Jan 10:114688. doi: 10.1016/j.expneurol.2024.114688.
    PubMed     Abstract available
    
    
    
57. YUBOLPHAN R, Pratchayasakul W, Koonrungsesomboon N, Chattipakorn N, et al
    Potential links between platelets and amyloid-beta in the pathogenesis of Alzheimer's disease: Evidence from in vitro, in vivo, and clinical studies.
    Exp Neurol. 2024 Jan 9:114683. doi: 10.1016/j.expneurol.2024.114683.
    PubMed     Abstract available
    
    
    
58. DEMBY T, Gross PS, Mandelblatt J, Huang JK, et al
    The chemotherapeutic agent doxorubicin induces brain senescence, with modulation by APOE genotype.
    Exp Neurol. 2024;371:114609.
    PubMed     Abstract available
    
    
    September 2023
59. HOSSEININIA M, Rostami F, Delphi L, Ghasemzadeh Z, et al
    Memory impairment was ameliorated by corticolimbic microinjections of arachidonylcyclopropylamide (ACPA) and miRNA-regulated lentiviral particles in a streptozotocin-induced Alzheimer's rat model.
    Exp Neurol. 2023 Sep 30:114560. doi: 10.1016/j.expneurol.2023.114560.
    PubMed     Abstract available
    
    
    
60. UPADHYAY P, Gupta S
    Dual mode of Triphala in the reversal of cognition through gut restoration in antibiotic mediated prolonged dysbiosis condition in 5XFAD mice.
    Exp Neurol. 2023;367:114473.
    PubMed     Abstract available
    
    
    August 2023
61. TIAN S, Ye T, Cheng X
    The behavioral, pathological and therapeutic features of the triple transgenic Alzheimer's disease (3 x Tg-AD) mouse model strain.
    Exp Neurol. 2023 Aug 17:114505. doi: 10.1016/j.expneurol.2023.114505.
    PubMed     Abstract available
    
    
    
62. HOSSAIN SR, Karem H, Jafari Z, Kolb BE, et al
    Early tactile stimulation influences the development of Alzheimer's disease in gestationally stressed APP (NL-G-F) adult offspring (NL-G-F/NL-G-F) mice.
    Exp Neurol. 2023 Aug 1:114498. doi: 10.1016/j.expneurol.2023.114498.
    PubMed     Abstract available
    
    
    June 2023
63. DU K, Dou Y, Chen K, Zhao Y, et al
    Activation of TRPV4 induces intraneuronal tau hyperphosphorylation via cholesterol accumulation.
    Exp Neurol. 2023;364:114392.
    PubMed     Abstract available
    
    
    May 2023
64. GHASEMI A, Qaffaripour Z, Tourani M, Saleki K, et al
    The relationship between long non-coding RNAs and Wnt/beta-catenin signaling pathway in the pathogenesis of Alzheimer's disease.
    Exp Neurol. 2023 May 16:114434. doi: 10.1016/j.expneurol.2023.114434.
    PubMed     Abstract available
    
    
    
65. WANG YY, Zhou YN, Jiang L, Wang S, et al
    Long-term voluntary exercise inhibited AGE/RAGE and microglial activation and reduced the loss of dendritic spines in the hippocampi of APP/PS1 transgenic mice.
    Exp Neurol. 2023;363:114371.
    PubMed     Abstract available
    
    
    April 2023
66. JAFARI Z, Afrashteh N, Kolb BE, Mohajerani MH, et al
    Hearing loss and impaired short-term memory in an Alzheimer's disease mouse model of amyloid-beta pathology.
    Exp Neurol. 2023 Apr 17:114413. doi: 10.1016/j.expneurol.2023.114413.
    PubMed     Abstract available
    
    
    
67. YANG YY, Ren YT, Jia MY, Bai CY, et al
    The human islet amyloid polypeptide reduces hippocampal tauopathy and behavioral impairments in P301S mice without inducing neurotoxicity or seeding amyloid aggregation.
    Exp Neurol. 2023;362:114346.
    PubMed     Abstract available
    
    
    
68. WU SL, Yu B, Cheng YJ, Ren SY, et al
    Brain region-specific myelinogenesis is not directly linked to amyloid-beta in APP/PS1 transgenic mice.
    Exp Neurol. 2023;362:114344.
    PubMed     Abstract available
    
    
    
69. LI L, Miao J, Jiang Y, Dai CL, et al
    Passive immunization inhibits tau phosphorylation and improves recognition learning and memory in 3xTg-AD mice.
    Exp Neurol. 2023;362:114337.
    PubMed     Abstract available
    
    
    March 2023
70. MEI Y, Li Y, Cheng YX, Gao L, et al
    The effect of gastric bypass surgery on cognitive function of Alzheimer's disease and the role of GLP1-SGLT1 pathway.
    Exp Neurol. 2023 Mar 7:114377. doi: 10.1016/j.expneurol.2023.114377.
    PubMed     Abstract available
    
    
    
71. WANG C, Chang Y, Zhu J, Wu Y, et al
    AdipoRon mitigates tau pathology and restores mitochondrial dynamics via AMPK-related pathway in a mouse model of Alzheimer's disease.
    Exp Neurol. 2023;363:114355.
    PubMed     Abstract available
    
    

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