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Articles published in Science

Retrieve available abstracts of 51 articles:
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Single Articles


    July 2026
  1. ZHANG Y, Lu X, Kunisky AK, Alam S, et al
    Single-cell multiomics connects 3D genome and transcriptome alterations in Alzheimer's disease.
    Science. 2026;393:eadz1652.
    PubMed     Abstract available


  2. SMITH JE
    Alzheimer's trial results lend momentum to drugs targeting tau.
    Science. 2026;393:343-344.
    PubMed     Abstract available


  3. CROWLEY G, Kim M, O'Neill N, Turkes E, et al
    C1q and immunoglobulins mediate activity-dependent synapse loss in the adult brain.
    Science. 2026;393:eadv1219.
    PubMed     Abstract available


    April 2026
  4. DE STROOPER B, Zetterberg H
    Tracking the turning point in Alzheimer's disease.
    Science. 2026;392:468-469.
    PubMed     Abstract available


  5. ZHANG L, Ma Q, Kong X, Zou W, et al
    Mapping transcription factor functions in astrocytes using in vivo gain-of-function Perturb-seq.
    Science. 2026;392:eadw2156.
    PubMed     Abstract available


  6. REINEKE LC, Zhu PJ, Dalwadi U, Dooling SW, et al
    Harnessing viral strategies to reverse cognitive dysfunction through the integrated stress response.
    Science. 2026;392:eaea8782.
    PubMed     Abstract available


  7. SMITH JE
    Scientists brace for expansion of Alzheimer's blood tests.
    Science. 2026;392:14-15.
    PubMed     Abstract available


    March 2026
  8. BOLES J, Gate D
    Astrocytes engineered to fight Alzheimer's plaques.
    Science. 2026;391:990-991.
    PubMed     Abstract available


  9. CHEN Y, Liu Y, Nguyen K, Wu J, et al
    Targeting amyloid-beta pathology by chimeric antigen receptor astrocyte (CAR-A) therapy.
    Science. 2026;391:eads3972.
    PubMed     Abstract available


    January 2026
  10. PILLER C
    Fake data from trial sites ruin studies, drug firms say.
    Science. 2026;391:112-114.
    PubMed     Abstract available


    December 2025

  11. Erratum for the Report "Site-specific phosphorylation of tau inhibits amyloid-beta toxicity in Alzheimer's mice" by A. Ittner et al.
    Science. 2025;390:eaee4634.
    PubMed    


    October 2025
  12. DEPP C
    White matters arising: Rethinking Alzheimer's disease through the lens of myelin.
    Science. 2025;390:483.
    PubMed     Abstract available


  13. DONG G, Ma CC, Mao S, Brown KS, et al
    Diverse somatic genomic alterations in single neurons in chronic traumatic encephalopathy.
    Science. 2025;390:eadu1351.
    PubMed     Abstract available


  14. CHANG M, Krussel S, Parajuli LK, Kim J, et al
    Intercellular communication in the brain through a dendritic nanotubular network.
    Science. 2025;390:eadr7403.
    PubMed     Abstract available


    August 2025
  15. XING M, Song W
    Improving Alzheimer's disease immunotherapy.
    Science. 2025;389:571-572.
    PubMed     Abstract available


  16. PIZZO ME, Plowey ED, Khoury N, Kwan W, et al
    Transferrin receptor-targeted anti-amyloid antibody enhances brain delivery and mitigates ARIA.
    Science. 2025;389:eads3204.
    PubMed     Abstract available


    July 2025
  17. KEIL SA, Jansson D, Braun M, Iliff JJ, et al
    Glymphatic dysfunction in Alzheimer's disease: A critical appraisal.
    Science. 2025;389:eadv8269.
    PubMed     Abstract available


  18. THORP HH
    Sluggishness and defensiveness helped enable an executive order on research integrity.
    Science. 2025;389:9.
    PubMed     Abstract available


    May 2025
  19. TOPOL E
    Predicting and preventing Alzheimer's disease.
    Science. 2025;388:eady3217.
    PubMed     Abstract available


    April 2025
  20. LESLIE M
    Risky moves.
    Science. 2025;388:244-247.
    PubMed     Abstract available


    February 2025
  21. ELLIOTT C
    A scientific field, misledDoctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's Charles Piller Atria/One Signal, 2025. 352 pp.
    Science. 2025;387:724.
    PubMed     Abstract available


    January 2025
  22. ELLIOTT C
    A scientific field, misledDoctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's Charles Piller Atria/One Signal, 2025. 352 pp.
    Science. 2025;387:724.
    PubMed     Abstract available


    November 2024
  23. LOPEZ-LEE C, Kodama L, Fan L, Zhu D, et al
    Tlr7 drives sex differences in age- and Alzheimer's disease-related demyelination.
    Science. 2024;386:eadk7844.
    PubMed     Abstract available


  24. COUZIN-FRANKEL J
    Preprint on Alzheimer's drug deaths ignites author dispute.
    Science. 2024;386:717-718.
    PubMed     Abstract available


  25. COUZIN-FRANKEL J
    Alzheimer's drug approvals create prescribing dilemmas.
    Science. 2024;386:472-473.
    PubMed     Abstract available


    October 2024
  26. PILLER C
    Firm misled investors on Alzheimer's drug, SEC charges.
    Science. 2024;386:15.
    PubMed     Abstract available


    September 2024
  27. WALKER LC, Jucker M
    The prion principle and Alzheimer's disease.
    Science. 2024;385:1278-1279.
    PubMed     Abstract available


  28. KAISER J
    The burden of a gene.
    Science. 2024;385:1154-1157.
    PubMed     Abstract available


    August 2024
  29. BENN J, Cheng S, Keeling S, Smith AE, et al
    Aggregate-selective removal of pathological tau by clustering-activated degraders.
    Science. 2024;385:1009-1016.
    PubMed     Abstract available


  30. JOHNSON LA, Macauley SL
    Alzheimer's and metabolism wed with IDO1.
    Science. 2024;385:826-827.
    PubMed     Abstract available


  31. MINHAS PS, Jones JR, Latif-Hernandez A, Sugiura Y, et al
    Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies.
    Science. 2024;385:eabm6131.
    PubMed     Abstract available


  32. COUZIN-FRANKEL J
    Hunt for infectious causes of Alzheimer's gains momentum.
    Science. 2024;385:479-480.
    PubMed     Abstract available


  33. SUN Z, Kwon JS, Ren Y, Chen S, et al
    Modeling late-onset Alzheimer's disease neuropathology via direct neuronal reprogramming.
    Science. 2024;385:adl2992.
    PubMed     Abstract available


    July 2024
  34. KIPNIS J
    The anatomy of brainwashing.
    Science. 2024;385:368-370.
    PubMed     Abstract available


    June 2024
  35. PARK J, Wang J, Guan W, Gjesteby LA, et al
    Integrated platform for multiscale molecular imaging and phenotyping of the human brain.
    Science. 2024;384:eadh9979.
    PubMed     Abstract available


  36. COUZIN-FRANKEL J
    New Alzheimer's drug clears FDA advisory vote despite unknowns.
    Science. 2024;384:1164-1165.
    PubMed     Abstract available


  37. PILLER C
    Authors move to retract discredited Alzheimer's study.
    Science. 2024;384:1055.
    PubMed     Abstract available


    May 2024
  38. PRINCEN K, Van Dooren T, van Gorsel M, Louros N, et al
    Pharmacological modulation of septins restores calcium homeostasis and is neuroprotective in models of Alzheimer's disease.
    Science. 2024;384:eadd6260.
    PubMed     Abstract available


  39. TOPOL EJ
    Medical forecasting.
    Science. 2024;384:eadp7977.
    PubMed     Abstract available


    March 2024
  40. PILLER C
    'Damning' FDA inspection report undermines Alzheimer's drug.
    Science. 2024;383:1165-1166.
    PubMed     Abstract available


    December 2023
  41. GOLDE TE, Levey AI
    Immunotherapies for Alzheimer's disease.
    Science. 2023;382:1242-1244.
    PubMed     Abstract available


    November 2023
  42. PILLER C
    Brain games?
    Science. 2023;382:754-759.
    PubMed     Abstract available


    October 2023
  43. PILLER C
    Probe of Alzheimer's studies finds 'egregious misconduct'.
    Science. 2023;382:251-252.
    PubMed     Abstract available


    September 2023
  44. BALUSU S, Horre K, Thrupp N, Craessaerts K, et al
    MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer's disease.
    Science. 2023;381:1176-1182.
    PubMed     Abstract available


  45. SIRKIS DW, Yokoyama JS
    Role for cell death pathway in Alzheimer's disease.
    Science. 2023;381:1156-1157.
    PubMed     Abstract available


  46. AGUZZI A, Kampmann M
    Neurodegeneration enters the era of functional genomics.
    Science. 2023;381:eadk5693.
    PubMed     Abstract available


    August 2023
  47. COUZIN-FRANKEL J
    Side effects loom over Alzheimer's drugs.
    Science. 2023;381:466-467.
    PubMed     Abstract available


    July 2023
  48. ZHANG ZY, Harischandra DS, Wang R, Ghaisas S, et al
    TRIM11 protects against tauopathies and is down-regulated in Alzheimer's disease.
    Science. 2023;381:eadd6696.
    PubMed     Abstract available


    May 2023
  49. TRAVIS J
    Latest Alzheimer's antibody is 'not a miracle drug'.
    Science. 2023;380:571.
    PubMed     Abstract available


    April 2023
  50. PILLER C
    Report on trial death stokes Alzheimer's drug fears.
    Science. 2023;380:122-123.
    PubMed     Abstract available


  51. COUZIN-FRANKEL J
    Promising Alzheimer's therapies shrink brains.
    Science. 2023;380:19.
    PubMed     Abstract available


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