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Articles published in J Clin Invest

Retrieve available abstracts of 23 articles:
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Single Articles


    April 2021
  1. MATTE A, Federti E, Kung C, Kosinski PA, et al
    The pyruvate kinase activator mitapivat reduces hemolysis and improves anemia in a beta-thalassemia mouse model.
    J Clin Invest. 2021 Apr 6. pii: 144206. doi: 10.1172/JCI144206.
    PubMed     Abstract available


    October 2020
  2. PFEFFERLE M, Ingoglia G, Schaer CA, Yalamanoglu A, et al
    Hemolysis transforms liver macrophages into antiinflammatory erythrophagocytes.
    J Clin Invest. 2020;130:5576-5590.
    PubMed     Abstract available


    July 2020
  3. CRISPIN A, Guo C, Chen C, Campagna DR, et al
    Mutations in the iron-sulfur cluster biogenesis protein HSCB cause congenital sideroblastic anemia.
    J Clin Invest. 2020 Jul 7. pii: 135479. doi: 10.1172/JCI135479.
    PubMed     Abstract available


    May 2020
  4. GAVRIILAKI E, Brodsky RA
    Complementopathies and precision medicine.
    J Clin Invest. 2020;130:2152-2163.
    PubMed     Abstract available


  5. FRANCIS RO, D'Alessandro A, Eisenberger A, Soffing M, et al
    Donor glucose-6-phosphate dehydrogenase deficiency decreases blood quality for transfusion.
    J Clin Invest. 2020;130:2270-2285.
    PubMed     Abstract available


    April 2020
  6. KREUTMAIR S, Erlacher M, Andrieux G, Istvanffy R, et al
    Loss of the Fanconi anemia-associated protein NIPA causes bone marrow failure.
    J Clin Invest. 2020 Apr 27. pii: 126215. doi: 10.1172/JCI126215.
    PubMed     Abstract available


    March 2020
  7. HEBBEL RP, Belcher JD, Vercellotti GM
    The multifaceted role of ischemia/reperfusion in sickle cell anemia.
    J Clin Invest. 2020;130:1062-1072.
    PubMed     Abstract available


    January 2020
  8. ASHLEY RJ, Yan H, Wang N, Hale J, et al
    Steroid-resistance in Diamond Blackfan anemia associates with p57Kip2 dysregulation in erythroid progenitors.
    J Clin Invest. 2020 Jan 21. pii: 132284. doi: 10.1172/JCI132284.
    PubMed     Abstract available


  9. SANKARAN VG, Ulirsch JC, Tchaikovskii V, Ludwig LS, et al
    X-linked macrocytic dyserythropoietic anemia in females with an ALAS2 mutation.
    J Clin Invest. 2020;130:552.
    PubMed    


  10. BEDIN M, Boyer O, Servais A, Li Y, et al
    Human C-terminal CUBN variants associate with chronic proteinuria and normal renal function.
    J Clin Invest. 2020;130:335-344.
    PubMed     Abstract available


  11. BRODSKY RA, DeBaun MR
    Are genetic approaches still needed to cure sickle cell disease?
    J Clin Invest. 2020;130:7-9.
    PubMed    


    December 2019
  12. OPPEZZO A, Bourseguin J, Renaud E, Pawlikowska P, et al
    Microphthalmia transcription factor expression contributes to bone marrow failure in Fanconi anemia.
    J Clin Invest. 2019 Dec 26. pii: 131540. doi: 10.1172/JCI131540.
    PubMed     Abstract available


    June 2019
  13. MOHANDAS N
    Anemia lurking in introns.
    J Clin Invest. 2019;130.
    PubMed     Abstract available


    April 2019
  14. GALLAGHER PG, Maksimova Y, Lezon-Geyda K, Newburger PE, et al
    Aberrant splicing contributes to severe alpha-spectrin-linked congenital hemolytic anemia.
    J Clin Invest. 2019;130.
    PubMed     Abstract available


    March 2019
  15. SMITH-JACKSON K, Yang Y, Denton H, Pappworth IY, et al
    Hyperfunctional complement C3 promotes C5-dependent atypical hemolytic uremic syndrome in mice.
    J Clin Invest. 2019;129:1061-1075.
    PubMed     Abstract available


    February 2019
  16. CRIPPA S, Rossella V, Aprile A, Silvestri L, et al
    Bone marrow stromal cells from beta-thalassemia patients have impaired hematopoietic supportive capacity.
    J Clin Invest. 2019;129:1566-1580.
    PubMed     Abstract available


    January 2019
  17. LEE FS
    At the crossroads of oxygen and iron sensing: hepcidin control of HIF-2alpha.
    J Clin Invest. 2019;129:72-74.
    PubMed     Abstract available


  18. SCHWARTZ AJ, Das NK, Ramakrishnan SK, Jain C, et al
    Hepatic hepcidin/intestinal HIF-2alpha axis maintains iron absorption during iron deficiency and overload.
    J Clin Invest. 2019;129:336-348.
    PubMed     Abstract available


    November 2018
  19. WANG H, Georgakopoulou A, Psatha N, Li C, et al
    In vivo hematopoietic stem cell gene therapy ameliorates murine thalassemia intermedia.
    J Clin Invest. 2018 Nov 13. pii: 122836. doi: 10.1172/JCI122836.
    PubMed     Abstract available


    July 2017
  20. KNIES K, Inano S, Ramirez MJ, Ishiai M, et al
    Biallelic mutations in the ubiquitin ligase RFWD3 cause Fanconi anemia.
    J Clin Invest. 2017 Jul 10. pii: 92069. doi: 10.1172/JCI92069.
    PubMed     Abstract available


    May 2017
  21. RYU MS, Zhang D, Protchenko O, Shakoury-Elizeh M, et al
    PCBP1 and NCOA4 regulate erythroid iron storage and heme biosynthesis.
    J Clin Invest. 2017;127:1786-1797.
    PubMed     Abstract available


    March 2017
  22. BLUTEAU D, Masliah-Planchon J, Clairmont C, Rousseau A, et al
    Biallelic inactivation of REV7 is associated with Fanconi anemia.
    J Clin Invest. 2017;127:1117.
    PubMed    


  23. KATO GJ, Steinberg MH, Gladwin MT
    Intravascular hemolysis and the pathophysiology of sickle cell disease.
    J Clin Invest. 2017;127:750-760.
    PubMed     Abstract available


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