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Articles published in N Engl J Med

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Single Articles


    April 2021
  1. LEVIN A
    Therapy for Anemia in Chronic Kidney Disease - New Interventions and New Questions.
    N Engl J Med. 2021;384:1657-1658.
    PubMed    


  2. ECKARDT KU, Agarwal R, Aswad A, Awad A, et al
    Safety and Efficacy of Vadadustat for Anemia in Patients Undergoing Dialysis.
    N Engl J Med. 2021;384:1601-1612.
    PubMed     Abstract available


  3. CHERTOW GM, Pergola PE, Farag YMK, Agarwal R, et al
    Vadadustat in Patients with Anemia and Non-Dialysis-Dependent CKD.
    N Engl J Med. 2021;384:1589-1600.
    PubMed     Abstract available


  4. ROTH A, Barcellini W, D'Sa S, Miyakawa Y, et al
    Sutimlimab in Cold Agglutinin Disease.
    N Engl J Med. 2021;384:1323-1334.
    PubMed     Abstract available


    March 2021
  5. HILLMEN P, Szer J, Weitz I, Roth A, et al
    Pegcetacoplan versus Eculizumab in Paroxysmal Nocturnal Hemoglobinuria.
    N Engl J Med. 2021;384:1028-1037.
    PubMed     Abstract available


  6. OGUNWOLE SM
    Without Sanctuary.
    N Engl J Med. 2021;384:791-793.
    PubMed    


    February 2021
  7. MENON BS, Teh KH
    Gum Hypertrophy from Cyclosporine.
    N Engl J Med. 2021;384:744.
    PubMed    


  8. TAHER AT, Musallam KM, Cappellini MD
    beta-Thalassemias.
    N Engl J Med. 2021;384:727-743.
    PubMed    


    January 2021
  9. MALECH HL
    Treatment by CRISPR-Cas9 Gene Editing - A Proof of Principle.
    N Engl J Med. 2021;384:286-287.
    PubMed    


  10. WALTERS MC
    Induction of Fetal Hemoglobin by Gene Therapy.
    N Engl J Med. 2021;384:284-285.
    PubMed    


  11. ESRICK EB, Lehmann LE, Biffi A, Achebe M, et al
    Post-Transcriptional Genetic Silencing of BCL11A to Treat Sickle Cell Disease.
    N Engl J Med. 2021;384:205-215.
    PubMed     Abstract available


  12. FRANGOUL H, Altshuler D, Cappellini MD, Chen YS, et al
    CRISPR-Cas9 Gene Editing for Sickle Cell Disease and beta-Thalassemia.
    N Engl J Med. 2021;384:252-260.
    PubMed     Abstract available


    December 2020
  13. KIRPALANI H, Bell EF, Hintz SR, Tan S, et al
    Higher or Lower Hemoglobin Transfusion Thresholds for Preterm Infants.
    N Engl J Med. 2020;383:2639-2651.
    PubMed     Abstract available


  14. MENSAH F, Pilichowska M
    Hemophagocytosis of Sickle Cells.
    N Engl J Med. 2020;383:2571.
    PubMed    


  15. KWAMBAI TK, Dhabangi A, Idro R, Opoka R, et al
    Malaria Chemoprevention in the Postdischarge Management of Severe Anemia.
    N Engl J Med. 2020;383:2242-2254.
    PubMed     Abstract available


    November 2020
  16. MALHOTRA R, Namasivayam M, Ghoshhajra BB, Passeri JJ, et al
    Case 36-2020: A 72-Year-Old Woman with Dark Urine and Weakness.
    N Engl J Med. 2020;383:2066-2076.
    PubMed    


  17. POWER-HAYS A, McGann PT
    When Actions Speak Louder Than Words - Racism and Sickle Cell Disease.
    N Engl J Med. 2020;383:1902-1903.
    PubMed    


    August 2020
  18. YOUNG S, Chen L, Palatnick W, Wong P, et al
    Led Astray.
    N Engl J Med. 2020;383:578-583.
    PubMed    


    July 2020
  19. KAPLAN JM
    Roxadustat for Anemia in Patients with Chronic Kidney Disease. Reply.
    N Engl J Med. 2020;383:e3.
    PubMed    


  20. XIE J, Chen N
    Roxadustat for Anemia in Patients with Chronic Kidney Disease. Reply.
    N Engl J Med. 2020;383:e3.
    PubMed    


  21. SHAH HH, Fishbane S
    Roxadustat for Anemia in Patients with Chronic Kidney Disease.
    N Engl J Med. 2020;383:e3.
    PubMed    


  22. MOHANDAS R, Segal MS
    Roxadustat for Anemia in Patients with Chronic Kidney Disease.
    N Engl J Med. 2020;383:e3.
    PubMed    


  23. ZIELNIOK K, Burdzinska A, Paczek L
    Roxadustat for Anemia in Patients with Chronic Kidney Disease.
    N Engl J Med. 2020;383:e3.
    PubMed    


  24. ANKER MS, Butler J, Anker SD
    Roxadustat for Anemia in Patients with Chronic Kidney Disease.
    N Engl J Med. 2020;383:e3.
    PubMed    


    June 2020
  25. JOHN CC, Opoka RO, Latham TS, Hume HA, et al
    Hydroxyurea Dose Escalation for Sickle Cell Anemia in Sub-Saharan Africa.
    N Engl J Med. 2020;382:2524-2533.
    PubMed     Abstract available


    May 2020
  26. JUUL SE, Comstock BA, Heagerty PJ
    Erythropoietin in Preterm Infants. Reply.
    N Engl J Med. 2020;382:1862-1863.
    PubMed    


  27. EHRENREICH H, Neubauer AP, Miskowiak K
    Erythropoietin in Preterm Infants.
    N Engl J Med. 2020;382:1862.
    PubMed    


    March 2020
  28. CAPPELLINI MD, Viprakasit V, Taher AT, Georgiev P, et al
    A Phase 3 Trial of Luspatercept in Patients with Transfusion-Dependent beta-Thalassemia.
    N Engl J Med. 2020;382:1219-1231.
    PubMed     Abstract available


    February 2020
  29. ARAUJO PEREIRA J, Sousa Gomes M
    Twin Anemia Polycythemia Sequence.
    N Engl J Med. 2020;382:e9.
    PubMed    


    January 2020
  30. JUUL SE, Comstock BA, Wadhawan R, Mayock DE, et al
    A Randomized Trial of Erythropoietin for Neuroprotection in Preterm Infants.
    N Engl J Med. 2020;382:233-243.
    PubMed     Abstract available


  31. FENAUX P, Platzbecker U, Mufti GJ, Garcia-Manero G, et al
    Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes.
    N Engl J Med. 2020;382:140-151.
    PubMed     Abstract available


    November 2019
  32. CUMMINGS BM, Shailam R, Rosales AM, Huang MS, et al
    Case 37-2019: A 20-Month-Old Boy with Severe Anemia.
    N Engl J Med. 2019;381:2158-2167.
    PubMed    


  33. BRODSKY RA
    Warm Autoimmune Hemolytic Anemia. Reply.
    N Engl J Med. 2019;381:1881-1882.
    PubMed    


  34. SHVIDEL L, Stanevsky A, Sigler E
    Warm Autoimmune Hemolytic Anemia.
    N Engl J Med. 2019;381:1881.
    PubMed    


    October 2019
  35. MAITLAND K, Olupot-Olupot P, Walker AS
    Transfusion Timing and Volume in African Children with Severe Anemia. Reply.
    N Engl J Med. 2019;381:1687-1688.
    PubMed    


  36. SATO T, Takahashi K, Tasaki T
    Transfusion Timing and Volume in African Children with Severe Anemia.
    N Engl J Med. 2019;381:1686-1687.
    PubMed    


  37. ROBINSON AN, Loh JSP
    Atrophic Glossitis.
    N Engl J Med. 2019;381:1568.
    PubMed    


  38. VALLURUPALLI M, Divakaran S, Parnes A, Levy BD, et al
    The Element of Surprise.
    N Engl J Med. 2019;381:1365-1371.
    PubMed    


    September 2019
  39. VALLURUPALLI M, Vaidya A, Foote M, Jain N, et al
    The Element of Surprise.
    N Engl J Med. 2019;381:e28.
    PubMed    


  40. SHARMA K, Patel A
    Livedo Reticularis in Cold Agglutinin Disease.
    N Engl J Med. 2019;381:e27.
    PubMed    


  41. GANZ T
    Anemia of Inflammation.
    N Engl J Med. 2019;381:1148-1157.
    PubMed    


  42. PANNU AK, Manikandan G
    Disseminated Varicella Infection.
    N Engl J Med. 2019;381:e21.
    PubMed    


  43. GRACE RF, Rose C, Layton DM, Galacteros F, et al
    Safety and Efficacy of Mitapivat in Pyruvate Kinase Deficiency.
    N Engl J Med. 2019;381:933-944.
    PubMed     Abstract available


    August 2019
  44. BRODSKY RA
    Warm Autoimmune Hemolytic Anemia.
    N Engl J Med. 2019;381:647-654.
    PubMed    


  45. THOMPSON A
    A Targeted Agent for Sickle Cell Disease - Changing the Protein but Not the Gene.
    N Engl J Med. 2019;381:579-580.
    PubMed    


  46. VICHINSKY E, Hoppe CC, Ataga KI, Ware RE, et al
    A Phase 3 Randomized Trial of Voxelotor in Sickle Cell Disease.
    N Engl J Med. 2019;381:509-519.
    PubMed     Abstract available


  47. INGELFINGER JR
    Immediate Transfusion and Transfusion Volume in African Children with Severe Anemia.
    N Engl J Med. 2019;381:475-476.
    PubMed    


  48. MAITLAND K, Olupot-Olupot P, Kiguli S, Chagaluka G, et al
    Transfusion Volume for Children with Severe Anemia in Africa.
    N Engl J Med. 2019;381:420-431.
    PubMed     Abstract available


  49. MAITLAND K, Kiguli S, Olupot-Olupot P, Engoru C, et al
    Immediate Transfusion in African Children with Uncomplicated Severe Anemia.
    N Engl J Med. 2019;381:407-419.
    PubMed     Abstract available


  50. GOLDMAN RH, Weissmann L
    A Diagnosis to Chew On.
    N Engl J Med. 2019;381:466-473.
    PubMed    


  51. HIGH KA, Roncarolo MG
    Gene Therapy.
    N Engl J Med. 2019;381:455-464.
    PubMed    


    July 2019
  52. CHEN N, Hao C, Liu BC, Lin H, et al
    Roxadustat Treatment for Anemia in Patients Undergoing Long-Term Dialysis.
    N Engl J Med. 2019 Jul 24. doi: 10.1056/NEJMoa1901713.
    PubMed     Abstract available


  53. KAPLAN J
    Roxadustat and Anemia of Chronic Kidney Disease.
    N Engl J Med. 2019 Jul 24. doi: 10.1056/NEJMe1908978.
    PubMed    


  54. CHEN N, Hao C, Peng X, Lin H, et al
    Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis.
    N Engl J Med. 2019 Jul 24. doi: 10.1056/NEJMoa1813599.
    PubMed     Abstract available


  55. LEE I, Walker JB, Nozaki K, Willett LL, et al
    Weak and Winded.
    N Engl J Med. 2019;381:76-82.
    PubMed    


    February 2019
  56. AHMED J, Kumar A, Jafri F, Batool S, et al
    Low Incidence of Hospital-Onset Clostridium difficile Infection in Sickle Cell Disease.
    N Engl J Med. 2019;380:887-888.
    PubMed    


  57. BARDIA A, Mayer IA, Vahdat LT, Tolaney SM, et al
    Sacituzumab Govitecan-hziy in Refractory Metastatic Triple-Negative Breast Cancer.
    N Engl J Med. 2019;380:741-751.
    PubMed     Abstract available


  58. HOGAN C, Little BP, Carlson JCT, Freudenreich O, et al
    Case 5-2019: A 48-Year-Old Woman with Delusional Thinking and Paresthesia of the Right Hand.
    N Engl J Med. 2019;380:665-674.
    PubMed    


  59. BEN-CHETRIT E, Shavit L, Tvito A, Korem M, et al
    The Devil Is in the Details.
    N Engl J Med. 2019;380:581-586.
    PubMed    


    January 2019
  60. LLANOS-CUENTAS A, Lacerda MVG, Hien TT, Velez ID, et al
    Tafenoquine versus Primaquine to Prevent Relapse of Plasmodium vivax Malaria.
    N Engl J Med. 2019;380:229-241.
    PubMed     Abstract available


  61. LUZZATTO L, Makani J
    Hydroxyurea - An Essential Medicine for Sickle Cell Disease in Africa.
    N Engl J Med. 2019;380:187-189.
    PubMed    


    December 2018
  62. MENDE M, Sockel K
    Parvovirus B19 Infection.
    N Engl J Med. 2018;379:2361.
    PubMed    


  63. TSHILOLO L, Tomlinson G, Williams TN, Santos B, et al
    Hydroxyurea for Children with Sickle Cell Anemia in Sub-Saharan Africa.
    N Engl J Med. 2018 Dec 1. doi: 10.1056/NEJMoa1813598.
    PubMed     Abstract available


    November 2018
  64. HIDER RC, Hoffbrand AV
    The Role of Deferiprone in Iron Chelation.
    N Engl J Med. 2018;379:2140-2150.
    PubMed    


  65. ANKER MS, Haverkamp W, Anker SD
    A Phase 3 Trial of l-Glutamine in Sickle Cell Disease.
    N Engl J Med. 2018;379:1879.
    PubMed    


  66. GUDDATI AK, Kota V
    A Phase 3 Trial of l-Glutamine in Sickle Cell Disease.
    N Engl J Med. 2018;379:1879.
    PubMed    



  67. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease.
    N Engl J Med. 2018;379:1879-1880.
    PubMed    


  68. CHAPUY CI, Kaufman RM, Alyea EP, Connors JM, et al
    Daratumumab for Delayed Red-Cell Engraftment after Allogeneic Transplantation.
    N Engl J Med. 2018;379:1846-1850.
    PubMed     Abstract available


  69. ADVANI R, Flinn I, Popplewell L, Forero A, et al
    CD47 Blockade by Hu5F9-G4 and Rituximab in Non-Hodgkin's Lymphoma.
    N Engl J Med. 2018;379:1711-1721.
    PubMed     Abstract available


    October 2018
  70. MACDOUGALL IC, White C, Anker SD, Bhandari S, et al
    Intravenous Iron in Patients Undergoing Maintenance Hemodialysis.
    N Engl J Med. 2018 Oct 26. doi: 10.1056/NEJMoa1810742.
    PubMed     Abstract available


  71. YOUNG NS
    Aplastic Anemia.
    N Engl J Med. 2018;379:1643-1656.
    PubMed    


  72. PASRICHA SR, Drakesmith H
    Hemoglobinopathies in the Fetal Position.
    N Engl J Med. 2018;379:1675-1677.
    PubMed    


    August 2018
  73. GHAFFARI S, Pourafkari L
    Koilonychia in Iron-Deficiency Anemia.
    N Engl J Med. 2018;379:e13.
    PubMed    


  74. KEYSERLING K, Koprowski S
    Spur-Cell Anemia.
    N Engl J Med. 2018;379:774.
    PubMed    


    July 2018
  75. BENNETT SE, Schmitt WP, Stanford FC, Baron JM, et al
    Case 22-2018: A 64-Year-Old Man with Progressive Leg Weakness, Recurrent Falls, and Anemia.
    N Engl J Med. 2018;379:282-289.
    PubMed    


  76. MINNITI CP
    l-Glutamine and the Dawn of Combination Therapy for Sickle Cell Disease.
    N Engl J Med. 2018;379:292-294.
    PubMed    


  77. NIIHARA Y, Miller ST, Kanter J, Lanzkron S, et al
    A Phase 3 Trial of l-Glutamine in Sickle Cell Disease.
    N Engl J Med. 2018;379:226-235.
    PubMed     Abstract available


    June 2018
  78. KAO AY, Sagar P, Klig JE, Sharma A, et al
    Case 19-2018: A 15-Year-Old Girl with Acute Kidney Injury.
    N Engl J Med. 2018;378:2421-2429.
    PubMed    



  79. Horse versus Rabbit Antithymocyte Globulin in Acquired Aplastic Anemia.
    N Engl J Med. 2018 Jun 13. doi: 10.1056/NEJMx180020.
    PubMed    


    April 2018
  80. BIFFI A
    Gene Therapy as a Curative Option for beta-Thalassemia.
    N Engl J Med. 2018;378:1551-1552.
    PubMed    


  81. THOMPSON AA, Walters MC, Kwiatkowski J, Rasko JEJ, et al
    Gene Therapy in Patients with Transfusion-Dependent beta-Thalassemia.
    N Engl J Med. 2018;378:1479-1493.
    PubMed     Abstract available


    March 2018
  82. STEINER M, Ludemann J, Krammer-Steiner B
    Favism and Glucose-6-Phosphate Dehydrogenase Deficiency.
    N Engl J Med. 2018;378:1068.
    PubMed    


  83. WINTERBOURN CC, Cheah F-C
    Favism and Glucose-6-Phosphate Dehydrogenase Deficiency.
    N Engl J Med. 2018;378:1067-8.
    PubMed    


  84. ZAIDI AU, Callaghan MU, Ravindranath Y
    Favism and Glucose-6-Phosphate Dehydrogenase Deficiency.
    N Engl J Med. 2018;378:1067.
    PubMed    


  85. LUZZATTO L, Arese P
    Favism and Glucose-6-Phosphate Dehydrogenase Deficiency.
    N Engl J Med. 2018;378:1068-1069.
    PubMed    


    February 2018
  86. KNUESEL SJ, Guseh JS 2nd, Karp Leaf R, Ciaranello AL, et al
    Case 6-2018: A 35-Year-Old Woman with Headache, Subjective Fever, and Anemia.
    N Engl J Med. 2018;378:753-760.
    PubMed    


    January 2018
  87. GUPTA A, Jain P
    Calcified Spleen and Gallstones.
    N Engl J Med. 2018;378:380.
    PubMed    


  88. RICHTERMAN A, Vaidya A, Brown JM, Braun DA, et al
    In the Balance.
    N Engl J Med. 2018;378:e5.
    PubMed    


  89. LUZZATTO L, Arese P
    Favism and Glucose-6-Phosphate Dehydrogenase Deficiency.
    N Engl J Med. 2018;378:60-71.
    PubMed    


    December 2017
  90. SYKES DB, Rosovsky RP, Singhal AB, Gonzalez RG, et al
    Case 40-2017. A 32-Year-Old Woman with Headache, Abdominal Pain, Anemia, and Thrombocytopenia.
    N Engl J Med. 2017;377:2581-2590.
    PubMed    


    November 2017
  91. DHALIWAL G, Mojtahed A, Fogerty AE, Kadauke S, et al
    Case 36-2017. A 30-Year-Old Man with Fatigue, Rash, Anemia, and Thrombocytopenia.
    N Engl J Med. 2017;377:2074-2083.
    PubMed    


  92. RENCIC J, Zhou M, Hsu G, Dhaliwal G, et al
    Circling Back for the Diagnosis.
    N Engl J Med. 2017;377:1778-1784.
    PubMed    


    July 2017
  93. MILUNSKY A
    Sickle Cell Disease.
    N Engl J Med. 2017;377:304-5.
    PubMed    


  94. SMITH ER, Heeney M, Scott RM
    Sickle Cell Disease.
    N Engl J Med. 2017;377:304.
    PubMed    


  95. PIEL FB, Steinberg MH, Rees DC
    Sickle Cell Disease.
    N Engl J Med. 2017;377:305.
    PubMed    


  96. LIONNET F, Haymann JP, Bachmeyer C
    Sickle Cell Disease.
    N Engl J Med. 2017;377:304.
    PubMed    


  97. BIBAS M
    Sickle Cell Disease.
    N Engl J Med. 2017;377:303-304.
    PubMed    


  98. INUSA B, Popoola J, Wonkam A
    Sickle Cell Disease.
    N Engl J Med. 2017;377:302-303.
    PubMed    


    May 2017
  99. BADAT M, Davies J
    Gene Therapy in a Patient with Sickle Cell Disease.
    N Engl J Med. 2017;376:2093-4.
    PubMed    


  100. LEBOULCH P, Cavazzana M
    Gene Therapy in a Patient with Sickle Cell Disease.
    N Engl J Med. 2017;376:2094.
    PubMed    



  101. Gene Therapy in a Patient with Sickle Cell Disease.
    N Engl J Med. 2017;376:2093-2094.
    PubMed    


  102. MANSOUR MK, Letourneau AR, Wallace ZS, Fintelmann FJ, et al
    Case 15-2017 - A 27-Year-Old Woman with Anemia, Thrombocytosis, and Skin Lesions after Travel Abroad.
    N Engl J Med. 2017;376:1973-1981.
    PubMed    


  103. ATAGA KI, Kutlar A, Kanter J
    Crizanlizumab in Sickle Cell Disease.
    N Engl J Med. 2017;376:1796.
    PubMed    


  104. YU Z, Blankenship L, Jaiyesimi I
    Crizanlizumab in Sickle Cell Disease.
    N Engl J Med. 2017;376:1795-1796.
    PubMed    


    April 2017
  105. TOWNSLEY DM, Scheinberg P, Winkler T, Desmond R, et al
    Eltrombopag Added to Standard Immunosuppression for Aplastic Anemia.
    N Engl J Med. 2017;376:1540-1550.
    PubMed     Abstract available


  106. PIEL FB, Steinberg MH, Rees DC
    Sickle Cell Disease.
    N Engl J Med. 2017;376:1561-1573.
    PubMed    


  107. LAVERY K, Gilden DJ, Saint S, Judson MA, et al
    A Bare-Bones Approach.
    N Engl J Med. 2017;376:1371-1376.
    PubMed    


    March 2017
  108. WOOLLEY AE, Montgomery MW, Savage WJ, Achebe MO, et al
    Post-Babesiosis Warm Autoimmune Hemolytic Anemia.
    N Engl J Med. 2017;376:939-946.
    PubMed     Abstract available


  109. RIBEIL JA, Hacein-Bey-Abina S, Payen E, Magnani A, et al
    Gene Therapy in a Patient with Sickle Cell Disease.
    N Engl J Med. 2017;376:848-855.
    PubMed     Abstract available


  110. WAILOO K
    Sickle Cell Disease - A History of Progress and Peril.
    N Engl J Med. 2017;376:805-807.
    PubMed    


    January 2017
  111. BLUM S, Shapir N, Miari R, Lerner B, et al
    TARGT Gene Therapy Platform for Correction of Anemia in End-Stage Renal Disease.
    N Engl J Med. 2017;376:189-191.
    PubMed    


    December 2016
  112. ATAGA KI, Kutlar A, Kanter J, Liles D, et al
    Crizanlizumab for the Prevention of Pain Crises in Sickle Cell Disease.
    N Engl J Med. 2016.
    PubMed     Abstract available


    October 2016
  113. BANHIDY NF, Banhidy FP
    Sickle Cell Trait and Rhabdomyolysis among U.S. Army Soldiers.
    N Engl J Med. 2016;375:1695.
    PubMed    



  114. Sickle Cell Trait and Rhabdomyolysis among U.S. Army Soldiers.
    N Engl J Med. 2016;375:1695-1696.
    PubMed    


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