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Articles published in Proc Natl Acad Sci U S A

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Single Articles


    June 2022
  1. ZAHOOR I, Suhail H, Datta I, Ahmed ME, et al
    Blood-based untargeted metabolomics in relapsing-remitting multiple sclerosis revealed the testable therapeutic target.
    Proc Natl Acad Sci U S A. 2022;119:e2123265119.
    PubMed     Abstract available


  2. KIM S, Lu HC, Steelman AJ, Li J, et al
    Myeloid caspase-8 restricts RIPK3-dependent proinflammatory IL-1beta production and CD4 T cell activation in autoimmune demyelination.
    Proc Natl Acad Sci U S A. 2022;119:e2117636119.
    PubMed     Abstract available


  3. DAMATO V, Theorell J, Al-Diwani A, Kienzler AK, et al
    Rituximab abrogates aquaporin-4-specific germinal center activity in patients with neuromyelitis optica spectrum disorders.
    Proc Natl Acad Sci U S A. 2022;119:e2121804119.
    PubMed     Abstract available



  4. Correction for Chia et al., Identification of genetic risk loci and prioritization of genes and pathways for myasthenia gravis: a genome-wide association study.
    Proc Natl Acad Sci U S A. 2022;119:e2206754119.
    PubMed    


    May 2022
  5. MANRY J, Bastard P, Gervais A, Le Voyer T, et al
    The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies.
    Proc Natl Acad Sci U S A. 2022;119:e2200413119.
    PubMed     Abstract available


  6. KISSLER S
    Toward a precision medicine approach for autoimmunity.
    Proc Natl Acad Sci U S A. 2022;119:e2204841119.
    PubMed    


    April 2022
  7. YU L, He L, Gan B, Ti R, et al
    Structural insights into sphingosine-1-phosphate receptor activation.
    Proc Natl Acad Sci U S A. 2022;119:e2117716119.
    PubMed     Abstract available


  8. POLICHENI AN, Teh CE, Robbins A, Tuzlak S, et al
    PD-1 cooperates with AIRE-mediated tolerance to prevent lethal autoimmune disease.
    Proc Natl Acad Sci U S A. 2022;119:e2120149119.
    PubMed     Abstract available


  9. POSTIGO-FERNANDEZ J, Firdessa-Fite R, Creusot RJ
    Preclinical evaluation of a precision medicine approach to DNA vaccination in type 1 diabetes.
    Proc Natl Acad Sci U S A. 2022;119:e2110987119.
    PubMed     Abstract available


  10. HWANG D, Seyedsadr MS, Ishikawa LLW, Boehm A, et al
    CSF-1 maintains pathogenic but not homeostatic myeloid cells in the central nervous system during autoimmune neuroinflammation.
    Proc Natl Acad Sci U S A. 2022;119:e2111804119.
    PubMed     Abstract available


    March 2022
  11. SARRAZIN N, Chavret-Reculon E, Bachelin C, Felfli M, et al
    Failed remyelination of the nonhuman primate optic nerve leads to axon degeneration, retinal damages, and visual dysfunction.
    Proc Natl Acad Sci U S A. 2022;119:e2115973119.
    PubMed     Abstract available


  12. GUPTA A, Smith P, Bournazos S, Ravetch JV, et al
    A novel mouse strain optimized for chronic human antibody administration.
    Proc Natl Acad Sci U S A. 2022;119:e2123002119.
    PubMed     Abstract available


  13. CHUNDER R, Weier A, Maurer H, Luber N, et al
    Antibody cross-reactivity between casein and myelin-associated glycoprotein results in central nervous system demyelination.
    Proc Natl Acad Sci U S A. 2022;119:e2117034119.
    PubMed     Abstract available


    February 2022
  14. LIU D, Zhao Z, She Y, Zhang L, et al
    TRIM14 inhibits OPTN-mediated autophagic degradation of KDM4D to epigenetically regulate inflammation.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  15. AMENDT T, Allies G, Nicolo A, El Ayoubi O, et al
    Autoreactive antibodies control blood glucose by regulating insulin homeostasis.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  16. GUO X, Kimura A, Namekata K, Harada C, et al
    ASK1 signaling regulates phase-specific glial interactions during neuroinflammation.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  17. BUCALA RJ
    Targeting fibrocytes in autoimmunity.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed    


  18. CHIA R, Saez-Atienzar S, Murphy N, Chio A, et al
    Identification of genetic risk loci and prioritization of genes and pathways for myasthenia gravis: a genome-wide association study.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    January 2022
  19. WANG Y, Guo L, Yin X, McCarthy EC, et al
    Pathogenic TNF-alpha drives peripheral nerve inflammation in an Aire-deficient model of autoimmunity.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    December 2021
  20. MONAGHAN KL, Aesoph D, Ammer AG, Zheng W, et al
    Tetramerization of STAT5 promotes autoimmune-mediated neuroinflammation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  21. FERNANDO R, Caldera O, Smith TJ
    Therapeutic IGF-I receptor inhibition alters fibrocyte immune phenotype in thyroid-associated ophthalmopathy.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  22. CHANDRAN V, Bermudez ML, Koka M, Chandran B, et al
    Large-scale genomic study reveals robust activation of the immune system following advanced Inner Engineering meditation retreat.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  23. MA Q, Caillier SJ, Muzic S, Wilson MR, et al
    Specific hypomethylation programs underpin B cell activation in early multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  24. LANDEGREN N, Ishii N, Aranda-Guillen M, Gunnarsson HI, et al
    A gene-centric approach to biomarker discovery identifies transglutaminase 1 as an epidermal autoantigen.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  25. VAN DER VAART J, Bosmans L, Sijbesma SF, Knoops K, et al
    Adult mouse and human organoids derived from thyroid follicular cells and modeling of Graves' hyperthyroidism.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  26. IRIKI H, Takahashi H, Wada N, Nomura H, et al
    Peripheral tolerance by Treg via constraining OX40 signal in autoreactive T cells against desmoglein 3, a target antigen in pemphigus.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    November 2021
  27. FORAY AP, Candon S, Hildebrand S, Marquet C, et al
    De novo germline mutation in the dual specificity phosphatase 10 gene accelerates autoimmune diabetes.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  28. CHOI JK, Yu CR, Bing SJ, Jittayasothorn Y, et al
    IL-27-producing B-1a cells suppress neuroinflammation and CNS autoimmune diseases.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  29. VARATHARAJ A, Carare RO, Weller RO, Gawne-Cain M, et al
    Gadolinium enhancement of cranial nerves: Implications for interstitial fluid drainage from brainstem into cranial nerves in humans.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  30. VON HERRATH M, Bonifacio E
    How benign autoimmunity becomes detrimental in type 1 diabetes.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  31. WANG J, Jalali Motlagh N, Wang C, Wojtkiewicz GR, et al
    d-mannose suppresses oxidative response and blocks phagocytosis in experimental neuroinflammation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    October 2021
  32. RAMIREZ DG, Ciccaglione M, Upadhyay AK, Pham VT, et al
    Detecting insulitis in type 1 diabetes with ultrasound phase-change contrast agents.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  33. ANDERSON AM, Landry LG, Alkanani AA, Pyle L, et al
    Human islet T cells are highly reactive to preproinsulin in type 1 diabetes.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  34. MANOUCHEHRI N, Stuve O
    Choroid plexus volumetrics and brain inflammation in multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


    September 2021
  35. YANG K, O'Cearbhaill ED, Liu SS, Zhou A, et al
    A therapeutic convection-enhanced macroencapsulation device for enhancing beta cell viability and insulin secretion.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  36. FLEISCHER V, Gonzalez-Escamilla G, Ciolac D, Albrecht P, et al
    Translational value of choroid plexus imaging for tracking neuroinflammation in mice and humans.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  37. HARTLEHNERT M, Borsch AL, Li X, Burmeister M, et al
    Bcl6 controls meningeal Th17-B cell interaction in murine neuroinflammation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    August 2021
  38. LAROCHELLE C, Wasser B, Jamann H, Loffel JT, et al
    Pro-inflammatory T helper 17 directly harms oligodendrocytes in neuroinflammation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  39. SINGH KD, Jara ZP, Harford T, Saha PP, et al
    Novel allosteric ligands of the angiotensin receptor AT1R as autoantibody blockers.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  40. LONGBRAKE EE, Hafler DA
    (23)Na imaging: Worth its salt for understanding multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  41. JING X, Yao Y, Wu D, Hong H, et al
    IFP35 family proteins promote neuroinflammation and multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    July 2021
  42. JUUL-MADSEN K, Troldborg A, Wittenborn TR, Axelsen MG, et al
    Characterization of DNA-protein complexes by nanoparticle tracking analysis and their association with systemic lupus erythematosus.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available



  43. Correction for Ostkamp et al., Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  44. BRYAN CM, Rocklin GJ, Bick MJ, Ford A, et al
    Computational design of a synthetic PD-1 agonist.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  45. HUHN K, Linz P, Pemsel F, Michalke B, et al
    Skin sodium is increased in male patients with multiple sclerosis and related animal models.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  46. COLOMBO E, Triolo D, Bassani C, Bedogni F, et al
    Dysregulated copper transport in multiple sclerosis may cause demyelination via astrocytes.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    June 2021
  47. PATERGNANI S, Bonora M, Ingusci S, Previati M, et al
    Antipsychotic drugs counteract autophagy and mitophagy in multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  48. PYFROM S, Paneru B, Knox JJ, Cancro MP, et al
    The dynamic epigenetic regulation of the inactive X chromosome in healthy human B cells is dysregulated in lupus patients.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    May 2021
  49. HUANG YS, Tseng WY, Clanchy FIL, Topping LM, et al
    Pharmacological modulation of T cell immunity results in long-term remission of autoimmune arthritis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  50. UMEDA M, Yoshida N, Hisada R, Burbano C, et al
    ADAM9 enhances Th17 cell differentiation and autoimmunity by activating TGF-beta1.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  51. BARNES SE, Han MH
    CD317 puts the brakes on dendritic cell trafficking to the CNS.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


    April 2021
  52. ZHELEZNYAKOVA GY, Piket E, Needhamsen M, Hagemann-Jensen M, et al
    Small noncoding RNA profiling across cellular and biofluid compartments and their implications for multiple sclerosis immunopathology.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available



  53. Correction to Supporting Information for Luo et al., The conserved autoimmune-disease risk gene TMEM39A regulates lysosome dynamics.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  54. MANOUCHEHRI N, Hussain RZ, Cravens PD, Esaulova E, et al
    CD11c(+)CD88(+)CD317(+) myeloid cells are critical mediators of persistent CNS autoimmunity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    March 2021
  55. RONIN E, Pouchy C, Khosravi M, Hilaire M, et al
    Tissue-restricted control of established central nervous system autoimmunity by TNF receptor 2-expressing Treg cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  56. VERGOOSSEN DLE, Plomp JJ, Gstottner C, Fillie-Grijpma YE, et al
    Functional monovalency amplifies the pathogenicity of anti-MuSK IgG4 in myasthenia gravis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  57. NA SY, Janakiraman M, Leliavski A, Krishnamoorthy G, et al
    High-salt diet suppresses autoimmune demyelination by regulating the blood-brain barrier permeability.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  58. SUN T, Yu Y, Wu X, Acevedo A, et al
    Decoupling expression and editing preferences of ADAR1 p150 and p110 isoforms.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  59. RAVENEY BJE, Sato W, Takewaki D, Zhang C, et al
    Involvement of cytotoxic Eomes-expressing CD4(+) T cells in secondary progressive multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  60. TOROK O, Schreiner B, Schaffenrath J, Tsai HC, et al
    Pericytes regulate vascular immune homeostasis in the CNS.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  61. BRANDLE SM, Cerina M, Weber S, Held K, et al
    Cross-reactivity of a pathogenic autoantibody to a tumor antigen in GABAA receptor encephalitis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  62. WANG MY, Dean ED, Quittner-Strom E, Zhu Y, et al
    Glucagon blockade restores functional beta-cell mass in type 1 diabetic mice and enhances function of human islets.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    February 2021
  63. KHAW YM, Tierney A, Cunningham C, Soto-Diaz K, et al
    Astrocytes lure CXCR2-expressing CD4(+) T cells to gray matter via TAK1-mediated chemokine production in a mouse model of multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  64. TEO W, Caprariello AV, Morgan ML, Luchicchi A, et al
    Nile Red fluorescence spectroscopy reports early physicochemical changes in myelin with high sensitivity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  65. LUO S, Wang X, Bai M, Jiang W, et al
    The conserved autoimmune-disease risk gene TMEM39A regulates lysosome dynamics.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  66. MITCHELL AM, Alkanani AA, McDaniel KA, Pyle L, et al
    T-cell responses to hybrid insulin peptides prior to type 1 diabetes development.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  67. MUNOZ M, Hegazy AN, Brunner TM, Holecska V, et al
    Th2 cells lacking T-bet suppress naive and memory T cell responses via IL-10.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    January 2021
  68. OSTKAMP P, Salmen A, Pignolet B, Gorlich D, et al
    Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  69. APICCO DJ, Shlevkov E, Nezich CL, Tran DT, et al
    The Parkinson's disease-associated gene ITPKB protects against alpha-synuclein aggregation by regulating ER-to-mitochondria calcium release.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  70. MARSLAND R 3RD, Howell O, Mayer A, Mehta P, et al
    Tregs self-organize into a computing ecosystem and implement a sophisticated optimization algorithm for mediating immune response.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    December 2020
  71. KENISON JE, Jhaveri A, Li Z, Khadse N, et al
    Tolerogenic nanoparticles suppress central nervous system inflammation.
    Proc Natl Acad Sci U S A. 2020;117:32017-32028.
    PubMed     Abstract available


  72. LISAK RP, Richman DP
    Thymectomy and myasthenia gravis.
    Proc Natl Acad Sci U S A. 2020 Dec 3. pii: 2022901117.
    PubMed    


    November 2020
  73. WANG Z, Wang J, Li H, Yu J, et al
    Dual self-regulated delivery of insulin and glucagon by a hybrid patch.
    Proc Natl Acad Sci U S A. 2020;117:29512-29517.
    PubMed     Abstract available


  74. TANG S, Zhang M, Zeng S, Huang Y, et al
    Reversal of autoimmunity by mixed chimerism enables reactivation of beta cells and transdifferentiation of alpha cells in diabetic NOD mice.
    Proc Natl Acad Sci U S A. 2020 Nov 23. pii: 2012389117.
    PubMed     Abstract available


  75. JIANG R, Hoehn KB, Lee CS, Pham MC, et al
    Thymus-derived B cell clones persist in the circulation after thymectomy in myasthenia gravis.
    Proc Natl Acad Sci U S A. 2020 Nov 16. pii: 2007206117.
    PubMed     Abstract available


  76. SUN S, Luo L, Liang W, Yin Q, et al
    Bifidobacterium alters the gut microbiota and modulates the functional metabolism of T regulatory cells in the context of immune checkpoint blockade.
    Proc Natl Acad Sci U S A. 2020;117:27509-27515.
    PubMed     Abstract available


    October 2020
  77. COX LM, Weiner HL
    The microbiome requires a genetically susceptible host to induce central nervous system autoimmunity.
    Proc Natl Acad Sci U S A. 2020 Oct 29. pii: 2020106117.
    PubMed    


  78. MONTGOMERY TL, Kunstner A, Kennedy JJ, Fang Q, et al
    Interactions between host genetics and gut microbiota determine susceptibility to CNS autoimmunity.
    Proc Natl Acad Sci U S A. 2020 Oct 19. pii: 2002817117.
    PubMed     Abstract available


  79. MCGOWAN J, Peter C, Kim J, Popli S, et al
    14-3-3zeta-TRAF5 axis governs interleukin-17A signaling.
    Proc Natl Acad Sci U S A. 2020;117:25008-25017.
    PubMed     Abstract available


  80. DAOU S, Talukdar M, Tang J, Dong B, et al
    A phenolic small molecule inhibitor of RNase L prevents cell death from ADAR1 deficiency.
    Proc Natl Acad Sci U S A. 2020;117:24802-24812.
    PubMed     Abstract available


    September 2020
  81. NISSIMOV N, Hajiyeva Z, Torke S, Grondey K, et al
    B cells reappear less mature and more activated after their anti-CD20-mediated depletion in multiple sclerosis.
    Proc Natl Acad Sci U S A. 2020 Sep 30. pii: 2012249117.
    PubMed     Abstract available


  82. MONDANELLI G, Carvalho A, Puccetti P, Grohmann U, et al
    Reply to Han et al.: On track for an IDO1-based personalized therapy in autoimmunity.
    Proc Natl Acad Sci U S A. 2020;117:24037-24038.
    PubMed    


  83. HU Y, Hu Y, Xiao Y, Wen F, et al
    Genetic landscape and autoimmunity of monocytes in developing Vogt-Koyanagi-Harada disease.
    Proc Natl Acad Sci U S A. 2020 Sep 28. pii: 2002476117.
    PubMed     Abstract available


  84. MAYER CT, Nieke JP, Gazumyan A, Cipolla M, et al
    An apoptosis-dependent checkpoint for autoimmunity in memory B and plasma cells.
    Proc Natl Acad Sci U S A. 2020 Sep 22. pii: 2015372117.
    PubMed     Abstract available


  85. LIU W, Wang Z, Liu L, Yang Z, et al
    LncRNA Malat1 inhibition of TDP43 cleavage suppresses IRF3-initiated antiviral innate immunity.
    Proc Natl Acad Sci U S A. 2020;117:23695-23706.
    PubMed     Abstract available


  86. VILLOSLADA P, Zamvil SS
    The immune signatures of multiple sclerosis: Lessons from twin studies.
    Proc Natl Acad Sci U S A. 2020 Sep 14. pii: 2016711117.
    PubMed    


  87. DIDONNA A, Canto Puig E, Ma Q, Matsunaga A, et al
    Ataxin-1 regulates B cell function and the severity of autoimmune experimental encephalomyelitis.
    Proc Natl Acad Sci U S A. 2020 Sep 2. pii: 2003798117.
    PubMed     Abstract available


  88. MONDAL S, Kundu M, Jana M, Roy A, et al
    IL-12 p40 monomer is different from other IL-12 family members to selectively inhibit IL-12Rbeta1 internalization and suppress EAE.
    Proc Natl Acad Sci U S A. 2020;117:21557-21567.
    PubMed     Abstract available


    August 2020
  89. RAMESH A, Schubert RD, Greenfield AL, Dandekar R, et al
    A pathogenic and clonally expanded B cell transcriptome in active multiple sclerosis.
    Proc Natl Acad Sci U S A. 2020 Aug 28. pii: 2008523117.
    PubMed     Abstract available


  90. O'CONNELL GC, Alder ML, Smothers CG, Chang JHC, et al
    Large-scale informatic analysis to algorithmically identify blood biomarkers of neurological damage.
    Proc Natl Acad Sci U S A. 2020;117:20764-20775.
    PubMed     Abstract available


  91. TAKEWAKI D, Suda W, Sato W, Takayasu L, et al
    Alterations of the gut ecological and functional microenvironment in different stages of multiple sclerosis.
    Proc Natl Acad Sci U S A. 2020 Aug 24. pii: 2011703117.
    PubMed     Abstract available


  92. KUERTEN S, Lanz TV, Lingampalli N, Lahey LJ, et al
    Autoantibodies against central nervous system antigens in a subset of B cell-dominant multiple sclerosis patients.
    Proc Natl Acad Sci U S A. 2020 Aug 18. pii: 2011249117.
    PubMed     Abstract available


  93. GERDES LA, Janoschka C, Eveslage M, Mannig B, et al
    Immune signatures of prodromal multiple sclerosis in monozygotic twins.
    Proc Natl Acad Sci U S A. 2020 Aug 17. pii: 2003339117.
    PubMed     Abstract available


    July 2020
  94. OTHY S, Jairaman A, Dynes JL, Dong TX, et al
    Regulatory T cells suppress Th17 cell Ca(2+) signaling in the spinal cord during murine autoimmune neuroinflammation.
    Proc Natl Acad Sci U S A. 2020 Jul 30. pii: 2006895117.
    PubMed     Abstract available



  95. Correction for Morianos et al., Activin-A limits Th17 pathogenicity and autoimmune neuroinflammation via CD39 and CD73 ectonucleotidases and Hif1-alpha-dependent pathways.
    Proc Natl Acad Sci U S A. 2020 Jul 13. pii: 2012449117.
    PubMed    


    June 2020
  96. JING C, Castro-Dopico T, Richoz N, Tuong ZK, et al
    Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis.
    Proc Natl Acad Sci U S A. 2020 Jun 15. pii: 2000943117.
    PubMed     Abstract available


  97. EBERING A, Waisman A
    Time to activin on pathogenic T cells.
    Proc Natl Acad Sci U S A. 2020;117:12513-12514.
    PubMed    


  98. SINHA AA
    Checking autoimmune genetic risk to stratify immune checkpoint inhibitor responders.
    Proc Natl Acad Sci U S A. 2020 Jun 5. pii: 2007744117.
    PubMed    


    May 2020
  99. HUANG J, Khademi M, Fugger L, Lindhe O, et al
    Inflammation-related plasma and CSF biomarkers for multiple sclerosis.
    Proc Natl Acad Sci U S A. 2020 May 26. pii: 1912839117.
    PubMed     Abstract available


  100. KHAN Z, Di Nucci F, Kwan A, Hammer C, et al
    Polygenic risk for skin autoimmunity impacts immune checkpoint blockade in bladder cancer.
    Proc Natl Acad Sci U S A. 2020 May 19. pii: 1922867117.
    PubMed     Abstract available


  101. MALINOW R, Klein ME
    Reply to Hashimoto: Ketamine is not an opioid but requires opioid system for antidepressant actions.
    Proc Natl Acad Sci U S A. 2020 May 19. pii: 2002739117.
    PubMed    


  102. HALDER SK, Milner R
    Chronic mild hypoxia accelerates recovery from preexisting EAE by enhancing vascular integrity and apoptosis of infiltrated monocytes.
    Proc Natl Acad Sci U S A. 2020;117:11126-11135.
    PubMed     Abstract available


  103. MORIANOS I, Trochoutsou AI, Papadopoulou G, Semitekolou M, et al
    Activin-A limits Th17 pathogenicity and autoimmune neuroinflammation via CD39 and CD73 ectonucleotidases and Hif1-alpha-dependent pathways.
    Proc Natl Acad Sci U S A. 2020 May 14. pii: 1918196117.
    PubMed     Abstract available


    April 2020
  104. QADIR MMF, Alvarez-Cubela S, Klein D, van Dijk J, et al
    Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche.
    Proc Natl Acad Sci U S A. 2020 Apr 30. pii: 1918314117.
    PubMed     Abstract available


  105. WOLBERT J, Li X, Heming M, Mausberg AK, et al
    Redefining the heterogeneity of peripheral nerve cells in health and autoimmunity.
    Proc Natl Acad Sci U S A. 2020 Apr 15. pii: 1912139117.
    PubMed     Abstract available


  106. GONZALEZ-MORO I, Olazagoitia-Garmendia A, Colli ML, Cobo-Vuilleumier N, et al
    The T1D-associated lncRNA Lnc13 modulates human pancreatic beta cell inflammation by allele-specific stabilization of STAT1 mRNA.
    Proc Natl Acad Sci U S A. 2020 Apr 13. pii: 1914353117.
    PubMed     Abstract available


  107. ZHANG Y, Li X, Ciric B, Curtis MT, et al
    A dual effect of ursolic acid to the treatment of multiple sclerosis through both immunomodulation and direct remyelination.
    Proc Natl Acad Sci U S A. 2020 Apr 6. pii: 2000208117.
    PubMed     Abstract available


    March 2020
  108. POLINA I, Jansen HJ, Li T, Moghtadaei M, et al
    Loss of insulin signaling may contribute to atrial fibrillation and atrial electrical remodeling in type 1 diabetes.
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