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Articles published in Proc Natl Acad Sci U S A

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    August 2021
  1. SINGH KD, Jara ZP, Harford T, Saha PP, et al
    Novel allosteric ligands of the angiotensin receptor AT1R as autoantibody blockers.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  2. LONGBRAKE EE, Hafler DA
    (23)Na imaging: Worth its salt for understanding multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  3. JING X, Yao Y, Wu D, Hong H, et al
    IFP35 family proteins promote neuroinflammation and multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    July 2021
  4. JUUL-MADSEN K, Troldborg A, Wittenborn TR, Axelsen MG, et al
    Characterization of DNA-protein complexes by nanoparticle tracking analysis and their association with systemic lupus erythematosus.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available



  5. Correction for Ostkamp et al., Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  6. HUHN K, Linz P, Pemsel F, Michalke B, et al
    Skin sodium is increased in male patients with multiple sclerosis and related animal models.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  7. COLOMBO E, Triolo D, Bassani C, Bedogni F, et al
    Dysregulated copper transport in multiple sclerosis may cause demyelination via astrocytes.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    June 2021
  8. PATERGNANI S, Bonora M, Ingusci S, Previati M, et al
    Antipsychotic drugs counteract autophagy and mitophagy in multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    May 2021
  9. HUANG YS, Tseng WY, Clanchy FIL, Topping LM, et al
    Pharmacological modulation of T cell immunity results in long-term remission of autoimmune arthritis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  10. UMEDA M, Yoshida N, Hisada R, Burbano C, et al
    ADAM9 enhances Th17 cell differentiation and autoimmunity by activating TGF-beta1.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    April 2021
  11. ZHELEZNYAKOVA GY, Piket E, Needhamsen M, Hagemann-Jensen M, et al
    Small noncoding RNA profiling across cellular and biofluid compartments and their implications for multiple sclerosis immunopathology.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available



  12. Correction to Supporting Information for Luo et al., The conserved autoimmune-disease risk gene TMEM39A regulates lysosome dynamics.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  13. MANOUCHEHRI N, Hussain RZ, Cravens PD, Esaulova E, et al
    CD11c(+)CD88(+)CD317(+) myeloid cells are critical mediators of persistent CNS autoimmunity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    March 2021
  14. RONIN E, Pouchy C, Khosravi M, Hilaire M, et al
    Tissue-restricted control of established central nervous system autoimmunity by TNF receptor 2-expressing Treg cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  15. VERGOOSSEN DLE, Plomp JJ, Gstottner C, Fillie-Grijpma YE, et al
    Functional monovalency amplifies the pathogenicity of anti-MuSK IgG4 in myasthenia gravis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  16. NA SY, Janakiraman M, Leliavski A, Krishnamoorthy G, et al
    High-salt diet suppresses autoimmune demyelination by regulating the blood-brain barrier permeability.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  17. SUN T, Yu Y, Wu X, Acevedo A, et al
    Decoupling expression and editing preferences of ADAR1 p150 and p110 isoforms.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  18. RAVENEY BJE, Sato W, Takewaki D, Zhang C, et al
    Involvement of cytotoxic Eomes-expressing CD4(+) T cells in secondary progressive multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  19. TOROK O, Schreiner B, Schaffenrath J, Tsai HC, et al
    Pericytes regulate vascular immune homeostasis in the CNS.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  20. BRANDLE SM, Cerina M, Weber S, Held K, et al
    Cross-reactivity of a pathogenic autoantibody to a tumor antigen in GABAA receptor encephalitis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  21. WANG MY, Dean ED, Quittner-Strom E, Zhu Y, et al
    Glucagon blockade restores functional beta-cell mass in type 1 diabetic mice and enhances function of human islets.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    February 2021
  22. KHAW YM, Tierney A, Cunningham C, Soto-Diaz K, et al
    Astrocytes lure CXCR2-expressing CD4(+) T cells to gray matter via TAK1-mediated chemokine production in a mouse model of multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  23. TEO W, Caprariello AV, Morgan ML, Luchicchi A, et al
    Nile Red fluorescence spectroscopy reports early physicochemical changes in myelin with high sensitivity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  24. LUO S, Wang X, Bai M, Jiang W, et al
    The conserved autoimmune-disease risk gene TMEM39A regulates lysosome dynamics.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  25. MITCHELL AM, Alkanani AA, McDaniel KA, Pyle L, et al
    T-cell responses to hybrid insulin peptides prior to type 1 diabetes development.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  26. MUNOZ M, Hegazy AN, Brunner TM, Holecska V, et al
    Th2 cells lacking T-bet suppress naive and memory T cell responses via IL-10.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    January 2021
  27. OSTKAMP P, Salmen A, Pignolet B, Gorlich D, et al
    Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  28. APICCO DJ, Shlevkov E, Nezich CL, Tran DT, et al
    The Parkinson's disease-associated gene ITPKB protects against alpha-synuclein aggregation by regulating ER-to-mitochondria calcium release.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  29. MARSLAND R 3RD, Howell O, Mayer A, Mehta P, et al
    Tregs self-organize into a computing ecosystem and implement a sophisticated optimization algorithm for mediating immune response.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    December 2020
  30. KENISON JE, Jhaveri A, Li Z, Khadse N, et al
    Tolerogenic nanoparticles suppress central nervous system inflammation.
    Proc Natl Acad Sci U S A. 2020;117:32017-32028.
    PubMed     Abstract available


  31. LISAK RP, Richman DP
    Thymectomy and myasthenia gravis.
    Proc Natl Acad Sci U S A. 2020 Dec 3. pii: 2022901117.
    PubMed    


    November 2020
  32. WANG Z, Wang J, Li H, Yu J, et al
    Dual self-regulated delivery of insulin and glucagon by a hybrid patch.
    Proc Natl Acad Sci U S A. 2020;117:29512-29517.
    PubMed     Abstract available


  33. TANG S, Zhang M, Zeng S, Huang Y, et al
    Reversal of autoimmunity by mixed chimerism enables reactivation of beta cells and transdifferentiation of alpha cells in diabetic NOD mice.
    Proc Natl Acad Sci U S A. 2020 Nov 23. pii: 2012389117.
    PubMed     Abstract available


  34. JIANG R, Hoehn KB, Lee CS, Pham MC, et al
    Thymus-derived B cell clones persist in the circulation after thymectomy in myasthenia gravis.
    Proc Natl Acad Sci U S A. 2020 Nov 16. pii: 2007206117.
    PubMed     Abstract available


  35. SUN S, Luo L, Liang W, Yin Q, et al
    Bifidobacterium alters the gut microbiota and modulates the functional metabolism of T regulatory cells in the context of immune checkpoint blockade.
    Proc Natl Acad Sci U S A. 2020;117:27509-27515.
    PubMed     Abstract available


    October 2020
  36. COX LM, Weiner HL
    The microbiome requires a genetically susceptible host to induce central nervous system autoimmunity.
    Proc Natl Acad Sci U S A. 2020 Oct 29. pii: 2020106117.
    PubMed    


  37. MONTGOMERY TL, Kunstner A, Kennedy JJ, Fang Q, et al
    Interactions between host genetics and gut microbiota determine susceptibility to CNS autoimmunity.
    Proc Natl Acad Sci U S A. 2020 Oct 19. pii: 2002817117.
    PubMed     Abstract available


  38. MCGOWAN J, Peter C, Kim J, Popli S, et al
    14-3-3zeta-TRAF5 axis governs interleukin-17A signaling.
    Proc Natl Acad Sci U S A. 2020;117:25008-25017.
    PubMed     Abstract available


  39. DAOU S, Talukdar M, Tang J, Dong B, et al
    A phenolic small molecule inhibitor of RNase L prevents cell death from ADAR1 deficiency.
    Proc Natl Acad Sci U S A. 2020;117:24802-24812.
    PubMed     Abstract available


    September 2020
  40. NISSIMOV N, Hajiyeva Z, Torke S, Grondey K, et al
    B cells reappear less mature and more activated after their anti-CD20-mediated depletion in multiple sclerosis.
    Proc Natl Acad Sci U S A. 2020 Sep 30. pii: 2012249117.
    PubMed     Abstract available


  41. MONDANELLI G, Carvalho A, Puccetti P, Grohmann U, et al
    Reply to Han et al.: On track for an IDO1-based personalized therapy in autoimmunity.
    Proc Natl Acad Sci U S A. 2020;117:24037-24038.
    PubMed    


  42. HU Y, Hu Y, Xiao Y, Wen F, et al
    Genetic landscape and autoimmunity of monocytes in developing Vogt-Koyanagi-Harada disease.
    Proc Natl Acad Sci U S A. 2020 Sep 28. pii: 2002476117.
    PubMed     Abstract available


  43. MAYER CT, Nieke JP, Gazumyan A, Cipolla M, et al
    An apoptosis-dependent checkpoint for autoimmunity in memory B and plasma cells.
    Proc Natl Acad Sci U S A. 2020 Sep 22. pii: 2015372117.
    PubMed     Abstract available


  44. LIU W, Wang Z, Liu L, Yang Z, et al
    LncRNA Malat1 inhibition of TDP43 cleavage suppresses IRF3-initiated antiviral innate immunity.
    Proc Natl Acad Sci U S A. 2020;117:23695-23706.
    PubMed     Abstract available


  45. VILLOSLADA P, Zamvil SS
    The immune signatures of multiple sclerosis: Lessons from twin studies.
    Proc Natl Acad Sci U S A. 2020 Sep 14. pii: 2016711117.
    PubMed    


  46. DIDONNA A, Canto Puig E, Ma Q, Matsunaga A, et al
    Ataxin-1 regulates B cell function and the severity of autoimmune experimental encephalomyelitis.
    Proc Natl Acad Sci U S A. 2020 Sep 2. pii: 2003798117.
    PubMed     Abstract available


  47. MONDAL S, Kundu M, Jana M, Roy A, et al
    IL-12 p40 monomer is different from other IL-12 family members to selectively inhibit IL-12Rbeta1 internalization and suppress EAE.
    Proc Natl Acad Sci U S A. 2020;117:21557-21567.
    PubMed     Abstract available


    August 2020
  48. RAMESH A, Schubert RD, Greenfield AL, Dandekar R, et al
    A pathogenic and clonally expanded B cell transcriptome in active multiple sclerosis.
    Proc Natl Acad Sci U S A. 2020 Aug 28. pii: 2008523117.
    PubMed     Abstract available


  49. O'CONNELL GC, Alder ML, Smothers CG, Chang JHC, et al
    Large-scale informatic analysis to algorithmically identify blood biomarkers of neurological damage.
    Proc Natl Acad Sci U S A. 2020;117:20764-20775.
    PubMed     Abstract available


  50. TAKEWAKI D, Suda W, Sato W, Takayasu L, et al
    Alterations of the gut ecological and functional microenvironment in different stages of multiple sclerosis.
    Proc Natl Acad Sci U S A. 2020 Aug 24. pii: 2011703117.
    PubMed     Abstract available


  51. KUERTEN S, Lanz TV, Lingampalli N, Lahey LJ, et al
    Autoantibodies against central nervous system antigens in a subset of B cell-dominant multiple sclerosis patients.
    Proc Natl Acad Sci U S A. 2020 Aug 18. pii: 2011249117.
    PubMed     Abstract available


  52. GERDES LA, Janoschka C, Eveslage M, Mannig B, et al
    Immune signatures of prodromal multiple sclerosis in monozygotic twins.
    Proc Natl Acad Sci U S A. 2020 Aug 17. pii: 2003339117.
    PubMed     Abstract available


    July 2020
  53. OTHY S, Jairaman A, Dynes JL, Dong TX, et al
    Regulatory T cells suppress Th17 cell Ca(2+) signaling in the spinal cord during murine autoimmune neuroinflammation.
    Proc Natl Acad Sci U S A. 2020 Jul 30. pii: 2006895117.
    PubMed     Abstract available



  54. Correction for Morianos et al., Activin-A limits Th17 pathogenicity and autoimmune neuroinflammation via CD39 and CD73 ectonucleotidases and Hif1-alpha-dependent pathways.
    Proc Natl Acad Sci U S A. 2020 Jul 13. pii: 2012449117.
    PubMed    


    June 2020
  55. JING C, Castro-Dopico T, Richoz N, Tuong ZK, et al
    Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis.
    Proc Natl Acad Sci U S A. 2020 Jun 15. pii: 2000943117.
    PubMed     Abstract available


  56. EBERING A, Waisman A
    Time to activin on pathogenic T cells.
    Proc Natl Acad Sci U S A. 2020;117:12513-12514.
    PubMed    


  57. SINHA AA
    Checking autoimmune genetic risk to stratify immune checkpoint inhibitor responders.
    Proc Natl Acad Sci U S A. 2020 Jun 5. pii: 2007744117.
    PubMed    


    May 2020
  58. HUANG J, Khademi M, Fugger L, Lindhe O, et al
    Inflammation-related plasma and CSF biomarkers for multiple sclerosis.
    Proc Natl Acad Sci U S A. 2020 May 26. pii: 1912839117.
    PubMed     Abstract available


  59. KHAN Z, Di Nucci F, Kwan A, Hammer C, et al
    Polygenic risk for skin autoimmunity impacts immune checkpoint blockade in bladder cancer.
    Proc Natl Acad Sci U S A. 2020 May 19. pii: 1922867117.
    PubMed     Abstract available


  60. MALINOW R, Klein ME
    Reply to Hashimoto: Ketamine is not an opioid but requires opioid system for antidepressant actions.
    Proc Natl Acad Sci U S A. 2020 May 19. pii: 2002739117.
    PubMed    


  61. HALDER SK, Milner R
    Chronic mild hypoxia accelerates recovery from preexisting EAE by enhancing vascular integrity and apoptosis of infiltrated monocytes.
    Proc Natl Acad Sci U S A. 2020;117:11126-11135.
    PubMed     Abstract available


  62. MORIANOS I, Trochoutsou AI, Papadopoulou G, Semitekolou M, et al
    Activin-A limits Th17 pathogenicity and autoimmune neuroinflammation via CD39 and CD73 ectonucleotidases and Hif1-alpha-dependent pathways.
    Proc Natl Acad Sci U S A. 2020 May 14. pii: 1918196117.
    PubMed     Abstract available


    April 2020
  63. QADIR MMF, Alvarez-Cubela S, Klein D, van Dijk J, et al
    Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche.
    Proc Natl Acad Sci U S A. 2020 Apr 30. pii: 1918314117.
    PubMed     Abstract available


  64. WOLBERT J, Li X, Heming M, Mausberg AK, et al
    Redefining the heterogeneity of peripheral nerve cells in health and autoimmunity.
    Proc Natl Acad Sci U S A. 2020 Apr 15. pii: 1912139117.
    PubMed     Abstract available


  65. GONZALEZ-MORO I, Olazagoitia-Garmendia A, Colli ML, Cobo-Vuilleumier N, et al
    The T1D-associated lncRNA Lnc13 modulates human pancreatic beta cell inflammation by allele-specific stabilization of STAT1 mRNA.
    Proc Natl Acad Sci U S A. 2020 Apr 13. pii: 1914353117.
    PubMed     Abstract available


  66. ZHANG Y, Li X, Ciric B, Curtis MT, et al
    A dual effect of ursolic acid to the treatment of multiple sclerosis through both immunomodulation and direct remyelination.
    Proc Natl Acad Sci U S A. 2020 Apr 6. pii: 2000208117.
    PubMed     Abstract available


    March 2020
  67. POLINA I, Jansen HJ, Li T, Moghtadaei M, et al
    Loss of insulin signaling may contribute to atrial fibrillation and atrial electrical remodeling in type 1 diabetes.
    Proc Natl Acad Sci U S A. 2020 Mar 20. pii: 1914853117.
    PubMed     Abstract available


  68. FACCIOTTI F, Larghi P, Bosotti R, Vasco C, et al
    Evidence for a pathogenic role of extrafollicular, IL-10-producing CCR6(+)B helper T cells in systemic lupus erythematosus.
    Proc Natl Acad Sci U S A. 2020 Mar 17. pii: 1917834117.
    PubMed     Abstract available


  69. CRIBBS AP, Terlecki-Zaniewicz S, Philpott M, Baardman J, et al
    Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism.
    Proc Natl Acad Sci U S A. 2020;117:6056-6066.
    PubMed     Abstract available


  70. MARTINEZ ALLO VC, Hauk V, Sarbia N, Pinto NA, et al
    Suppression of age-related salivary gland autoimmunity by glycosylation-dependent galectin-1-driven immune inhibitory circuits.
    Proc Natl Acad Sci U S A. 2020 Mar 11. pii: 1922778117.
    PubMed     Abstract available


  71. PLATT MP, Bolding KA, Wayne CR, Chaudhry S, et al
    Th17 lymphocytes drive vascular and neuronal deficits in a mouse model of postinfectious autoimmune encephalitis.
    Proc Natl Acad Sci U S A. 2020 Mar 11. pii: 1911097117.
    PubMed     Abstract available


  72. GOEL RR, Wang X, O'Neil LJ, Nakabo S, et al
    Interferon lambda promotes immune dysregulation and tissue inflammation in TLR7-induced lupus.
    Proc Natl Acad Sci U S A. 2020;117:5409-5419.
    PubMed     Abstract available


  73. HOUBEN E, Janssens K, Hermans D, Vandooren J, et al
    Oncostatin M-induced astrocytic tissue inhibitor of metalloproteinases-1 drives remyelination.
    Proc Natl Acad Sci U S A. 2020;117:5028-5038.
    PubMed     Abstract available


    February 2020
  74. LU HC, Kim S, Steelman AJ, Tracy K, et al
    STAT3 signaling in myeloid cells promotes pathogenic myelin-specific T cell differentiation and autoimmune demyelination.
    Proc Natl Acad Sci U S A. 2020 Feb 24. pii: 1913997117.
    PubMed     Abstract available


  75. MONDANELLI G, Coletti A, Greco FA, Pallotta MT, et al
    Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation.
    Proc Natl Acad Sci U S A. 2020;117:3848-3857.
    PubMed     Abstract available


  76. STANBERY AG, Newman ZR, Barton GM
    Dysregulation of TLR9 in neonates leads to fatal inflammatory disease driven by IFN-gamma.
    Proc Natl Acad Sci U S A. 2020;117:3074-3082.
    PubMed     Abstract available


    January 2020
  77. ZHAO Y, Yamasaki R, Yamaguchi H, Nagata S, et al
    Oligodendroglial connexin 47 regulates neuroinflammation upon autoimmune demyelination in a novel mouse model of multiple sclerosis.
    Proc Natl Acad Sci U S A. 2020 Jan 13. pii: 1901294117.
    PubMed     Abstract available


    December 2019
  78. GOURH P, Safran SA, Alexander T, Boyden SE, et al
    HLA and autoantibodies define scleroderma subtypes and risk in African and European Americans and suggest a role for molecular mimicry.
    Proc Natl Acad Sci U S A. 2019 Dec 23. pii: 1906593116.
    PubMed     Abstract available


  79. HUSZTHY PC, Gopalakrishnan RP, Jacobsen JT, Haabeth OAW, et al
    B cell receptor ligation induces display of V-region peptides on MHC class II molecules to T cells.
    Proc Natl Acad Sci U S A. 2019;116:25850-25859.
    PubMed     Abstract available


  80. CASLIN B, Maguire C, Karmakar A, Mohler K, et al
    Alcohol shifts gut microbial networks and ameliorates a murine model of neuroinflammation in a sex-specific pattern.
    Proc Natl Acad Sci U S A. 2019;116:25808-25815.
    PubMed     Abstract available


  81. HALDER SK, Milner R
    A critical role for microglia in maintaining vascular integrity in the hypoxic spinal cord.
    Proc Natl Acad Sci U S A. 2019;116:26029-26037.
    PubMed     Abstract available


  82. BADAMI E, Cexus ONF, Quaratino S
    Activation-induced cell death of self-reactive regulatory T cells drives autoimmunity.
    Proc Natl Acad Sci U S A. 2019 Dec 9. pii: 1910281116.
    PubMed     Abstract available


  83. HAUPELTSHOFER S, Leichsenring T, Berg S, Pedreiturria X, et al
    Smad7 in intestinal CD4(+) T cells determines autoimmunity in a spontaneous model of multiple sclerosis.
    Proc Natl Acad Sci U S A. 2019 Dec 3. pii: 1905955116.
    PubMed     Abstract available


  84. WAISMAN A, Ebering A
    Unraveling the T-B tangle in anti-CD20 multiple sclerosis therapy.
    Proc Natl Acad Sci U S A. 2019 Dec 2. pii: 1919044116.
    PubMed    


    November 2019
  85. DESFOUGERES Y, Wilson MSC, Laha D, Miller GJ, et al
    ITPK1 mediates the lipid-independent synthesis of inositol phosphates controlled by metabolism.
    Proc Natl Acad Sci U S A. 2019 Nov 21. pii: 1911431116.
    PubMed     Abstract available


  86. MISTRY P, Nakabo S, O'Neil L, Goel RR, et al
    Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus.
    Proc Natl Acad Sci U S A. 2019 Nov 21. pii: 1908576116.
    PubMed     Abstract available


  87. SABATINO JJ JR, Wilson MR, Calabresi PA, Hauser SL, et al
    Anti-CD20 therapy depletes activated myelin-specific CD8(+) T cells in multiple sclerosis.
    Proc Natl Acad Sci U S A. 2019 Nov 20. pii: 1915309116.
    PubMed     Abstract available


  88. ARAYA P, Waugh KA, Sullivan KD, Nunez NG, et al
    Trisomy 21 dysregulates T cell lineages toward an autoimmunity-prone state associated with interferon hyperactivity.
    Proc Natl Acad Sci U S A. 2019 Nov 7. pii: 1908129116.
    PubMed     Abstract available


    October 2019
  89. CAHILL LS, Zhang MA, Ramaglia V, Whetstone H, et al
    Aged hind-limb clasping experimental autoimmune encephalomyelitis models aspects of the neurodegenerative process seen in multiple sclerosis.
    Proc Natl Acad Sci U S A. 2019 Oct 22. pii: 1915141116.
    PubMed     Abstract available


  90. IRVING AA, Marling SJ, Seeman J, Plum LA, et al
    UV light suppression of EAE (a mouse model of multiple sclerosis) is independent of vitamin D and its receptor.
    Proc Natl Acad Sci U S A. 2019 Oct 21. pii: 1913294116.
    PubMed     Abstract available


  91. ZHANG C, Raveney BJE, Hohjoh H, Tomi C, et al
    Extrapituitary prolactin promotes generation of Eomes-positive helper T cells mediating neuroinflammation.
    Proc Natl Acad Sci U S A. 2019;116:21131-21139.
    PubMed     Abstract available


  92. TAHIR SA, Gao J, Miura Y, Blando J, et al
    Autoimmune antibodies correlate with immune checkpoint therapy-induced toxicities.
    Proc Natl Acad Sci U S A. 2019 Oct 14. pii: 1908079116.
    PubMed     Abstract available


  93. INIGUEZ LP, de Mulder Rougvie M, Stearrett N, Jones RB, et al
    Transcriptomic analysis of human endogenous retroviruses in systemic lupus erythematosus.
    Proc Natl Acad Sci U S A. 2019 Oct 8. pii: 1907705116.
    PubMed    


  94. HOU L, Rao DA, Yuki K, Cooley J, et al
    SerpinB1 controls encephalitogenic T helper cells in neuroinflammation.
    Proc Natl Acad Sci U S A. 2019;116:20635-20643.
    PubMed     Abstract available


    September 2019
  95. PETERS E, Tompkins MK, Knoll MAZ, Ardoin SP, et al
    Despite high objective numeracy, lower numeric confidence relates to worse financial and medical outcomes.
    Proc Natl Acad Sci U S A. 2019;116:19386-19391.
    PubMed     Abstract available


  96. SHEN H, Ji Y, Xiong Y, Kim H, et al
    Medullary thymic epithelial NF-kB-inducing kinase (NIK)/IKKalpha pathway shapes autoimmunity and liver and lung homeostasis in mice.
    Proc Natl Acad Sci U S A. 2019 Sep 3. pii: 1901056116.
    PubMed     Abstract available


    August 2019
  97. RUPRECHT K, Mayer J
    On the origin of a pathogenic HERV-W envelope protein present in multiple sclerosis lesions.
    Proc Natl Acad Sci U S A. 2019 Aug 27. pii: 1911703116.
    PubMed    


  98. KREMER D, Perron H, Kury P
    Reply to Ruprecht and Mayer: Unearthing genomic fossils in the pathogenesis of multiple sclerosis.
    Proc Natl Acad Sci U S A. 2019 Aug 27. pii: 1912315116.
    PubMed    


  99. CHANG C, Loo CS, Zhao X, Solt LA, et al
    The nuclear receptor REV-ERBalpha modulates Th17 cell-mediated autoimmune disease.
    Proc Natl Acad Sci U S A. 2019 Aug 27. pii: 1907563116.
    PubMed     Abstract available


  100. ASHOURI JF, Hsu LY, Yu S, Rychkov D, et al
    Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis.
    Proc Natl Acad Sci U S A. 2019 Aug 27. pii: 1904271116.
    PubMed     Abstract available


  101. LI Y, James SJ, Wyllie DH, Wynne C, et al
    TMEM203 is a binding partner and regulator of STING-mediated inflammatory signaling in macrophages.
    Proc Natl Acad Sci U S A. 2019;116:16479-16488.
    PubMed     Abstract available


  102. TENGVALL K, Huang J, Hellstrom C, Kammer P, et al
    Molecular mimicry between Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 associates with multiple sclerosis risk.
    Proc Natl Acad Sci U S A. 2019 Aug 2. pii: 1902623116.
    PubMed     Abstract available


    July 2019
  103. PETERS A, Wekerle H
    Autoimmune diabetes mellitus and the leaky gut.
    Proc Natl Acad Sci U S A. 2019 Jul 9. pii: 1909224116.
    PubMed    


  104. LISAK RP
    Human retrovirus pHEV-W envelope protein and the pathogenesis of multiple sclerosis.
    Proc Natl Acad Sci U S A. 2019 Jul 9. pii: 1909786116.
    PubMed    


  105. BAYDYUK M, Cha DS, Hu J, Yamazaki R, et al
    Tracking the evolution of CNS remyelinating lesion in mice with neutral red dye.
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    July 2018
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