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  Autoimmune Disorders

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Articles published in Proc Natl Acad Sci U S A

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Single Articles


    February 2024
  1. IVERSEN R, Sollid LM
    Dissecting autoimmune encephalitis through the lens of intrathecal B cells.
    Proc Natl Acad Sci U S A. 2024;121:e2401337121.
    PubMed    


  2. ADAMS C, Manouchehrinia A, Quach HL, Quach DL, et al
    Evidence supports a causal association between allele-specific vitamin D receptor binding and multiple sclerosis among Europeans.
    Proc Natl Acad Sci U S A. 2024;121:e2302259121.
    PubMed     Abstract available


  3. CHEN Y, Chen K, Zhu H, Qin H, et al
    Methyltransferase Setd2 prevents T cell-mediated autoimmune diseases via phospholipid remodeling.
    Proc Natl Acad Sci U S A. 2024;121:e2314561121.
    PubMed     Abstract available


  4. THEORELL J, Harrison R, Williams R, Raybould MIJ, et al
    Ultrahigh frequencies of peripherally matured LGI1- and CASPR2-reactive B cells characterize the cerebrospinal fluid in autoimmune encephalitis.
    Proc Natl Acad Sci U S A. 2024;121:e2311049121.
    PubMed     Abstract available


  5. QIN C, Dong MH, Zhou LQ, Wang W, et al
    Single-cell analysis of refractory anti-SRP necrotizing myopathy treated with anti-BCMA CAR-T cell therapy.
    Proc Natl Acad Sci U S A. 2024;121:e2315990121.
    PubMed     Abstract available


  6. SELCK C, Jhala G, De George DJ, Kwong CJ, et al
    Extraislet expression of islet antigen boosts T cell exhaustion to partially prevent autoimmune diabetes.
    Proc Natl Acad Sci U S A. 2024;121:e2315419121.
    PubMed     Abstract available


    January 2024
  7. SUTTER PA, Willis CM, Menoret A, Nicaise AM, et al
    Astrocytic TIMP-1 regulates production of Anastellin, an inhibitor of oligodendrocyte differentiation and FTY720 responses.
    Proc Natl Acad Sci U S A. 2024;121:e2306816121.
    PubMed     Abstract available


  8. AHMED AR, Kalesinskas M, Kaveri SV
    Restoring immune tolerance in pemphigus vulgaris.
    Proc Natl Acad Sci U S A. 2024;121:e2317762121.
    PubMed     Abstract available


  9. GOTTLIEB A, Pham HPT, Saltarrelli JG, Lindsey JW, et al
    Expanded T lymphocytes in the cerebrospinal fluid of multiple sclerosis patients are specific for Epstein-Barr-virus-infected B cells.
    Proc Natl Acad Sci U S A. 2024;121:e2315857121.
    PubMed     Abstract available


    December 2023
  10. DIJKSTRA DJ, van de Bovenkamp FS, Abendstein L, Zuijderduijn R, et al
    Human anti-C1q autoantibodies bind specifically to solid-phase C1q and enhance phagocytosis but not complement activation.
    Proc Natl Acad Sci U S A. 2023;120:e2310666120.
    PubMed     Abstract available


  11. YE C, Clements SA, Gu W, Geurts AM, et al
    Deletion of Vbeta3(+)CD4(+) T cells by endogenous mouse mammary tumor virus 3 prevents type 1 diabetes induction by autoreactive CD8(+) T cells.
    Proc Natl Acad Sci U S A. 2023;120:e2312039120.
    PubMed     Abstract available


  12. SHIMO Y, Cathomas F, Lin HY, Chan KL, et al
    Social stress induces autoimmune responses against the brain.
    Proc Natl Acad Sci U S A. 2023;120:e2305778120.
    PubMed     Abstract available


    November 2023
  13. SCHMIDT H, Raj T, O'Neill TJ, Muschaweckh A, et al
    Unrestrained cleavage of Roquin-1 by MALT1 induces spontaneous T cell activation and the development of autoimmunity.
    Proc Natl Acad Sci U S A. 2023;120:e2309205120.
    PubMed     Abstract available


  14. THOMANN AS, McQuade CA, Pinjusic K, Kolz A, et al
    A B cell-driven EAE mouse model reveals the impact of B cell-derived cytokines on CNS autoimmunity.
    Proc Natl Acad Sci U S A. 2023;120:e2300733120.
    PubMed     Abstract available


    September 2023
  15. GRUCHOT J, Lewen I, Dietrich M, Reiche L, et al
    Transgenic expression of the HERV-W envelope protein leads to polarized glial cell populations and a neurodegenerative environment.
    Proc Natl Acad Sci U S A. 2023;120:e2308187120.
    PubMed     Abstract available


  16. GAN T, Wang D
    Picobirnaviruses encode proteins that are functional bacterial lysins.
    Proc Natl Acad Sci U S A. 2023;120:e2309647120.
    PubMed     Abstract available


  17. GARCIA CORRALES AV, Verberk SGS, Haidar M, Grajchen E, et al
    Fatty acid elongation by ELOVL6 hampers remyelination by promoting inflammatory foam cell formation during demyelination.
    Proc Natl Acad Sci U S A. 2023;120:e2301030120.
    PubMed     Abstract available


    August 2023
  18. CANTOR H
    Renegade T cell clones and autoimmune disease.
    Proc Natl Acad Sci U S A. 2023;120:e2310236120.
    PubMed    


    July 2023
  19. SAGAN SA, Moinfar Z, Moseley CE, Dandekar R, et al
    T cell deletional tolerance restricts AQP4 but not MOG CNS autoimmunity.
    Proc Natl Acad Sci U S A. 2023;120:e2306572120.
    PubMed     Abstract available


    June 2023
  20. SEYEDSADR M, Wang Y, Elzoheiry M, Shree Gopal S, et al
    IL-11 induces NLRP3 inflammasome activation in monocytes and inflammatory cell migration to the central nervous system.
    Proc Natl Acad Sci U S A. 2023;120:e2221007120.
    PubMed     Abstract available


  21. LOUZADA RA, Blandino-Rosano M, Flores S, Lubaczeuski C, et al
    GRHR agonist MR-409 protects beta-cells from streptozotocin-induced diabetes.
    Proc Natl Acad Sci U S A. 2023;120:e2209810120.
    PubMed     Abstract available


  22. URBONAVICIUTE V, Romero-Castillo L, Xu B, Luo H, et al
    Therapy targeting antigen-specific T cells by a peptide-based tolerizing vaccine against autoimmune arthritis.
    Proc Natl Acad Sci U S A. 2023;120:e2218668120.
    PubMed     Abstract available


    May 2023
  23. CAVERZASI E, Papinutto N, Cordano C, Kirkish G, et al
    MWF of the corpus callosum is a robust measure of remyelination: Results from the ReBUILD trial.
    Proc Natl Acad Sci U S A. 2023;120:e2217635120.
    PubMed     Abstract available


  24. ZHAO Z, Wang Y, Gao Y, Ju Y, et al
    The PRAK-NRF2 axis promotes the differentiation of Th17 cells by mediating the redox homeostasis and glycolysis.
    Proc Natl Acad Sci U S A. 2023;120:e2212613120.
    PubMed     Abstract available


  25. ZHANG W, Cao X, Zhong X, Wu H, et al
    SRC2 controls CD4(+) T cell activation via stimulating c-Myc-mediated upregulation of amino acid transporter Slc7a5.
    Proc Natl Acad Sci U S A. 2023;120:e2221352120.
    PubMed     Abstract available


    April 2023
  26. KAPATE N, Dunne M, Kumbhojkar N, Prakash S, et al
    A backpack-based myeloid cell therapy for multiple sclerosis.
    Proc Natl Acad Sci U S A. 2023;120:e2221535120.
    PubMed     Abstract available


  27. SONG Y, Bell DR, Ahmed R, Chan KC, et al
    A mutagenesis study of autoantigen optimization for potential T1D vaccine design.
    Proc Natl Acad Sci U S A. 2023;120:e2214430120.
    PubMed     Abstract available


  28. GHAREGHANI M, Zibara K, Rivest S
    Melatonin and vitamin D, two sides of the same coin, better to land on its edge to improve multiple sclerosis.
    Proc Natl Acad Sci U S A. 2023;120:e2219334120.
    PubMed     Abstract available


    March 2023
  29. MADER S, Ho S, Wong HK, Baier S, et al
    Dissection of complement and Fc-receptor-mediated pathomechanisms of autoantibodies to myelin oligodendrocyte glycoprotein.
    Proc Natl Acad Sci U S A. 2023;120:e2300648120.
    PubMed     Abstract available


  30. FERRIS ST, Liu T, Chen J, Ohara RA, et al
    WDFY4 deficiency in NOD mice ameliorates autoimmune diabetes and insulitis.
    Proc Natl Acad Sci U S A. 2023;120:e2219956120.
    PubMed     Abstract available


    February 2023
  31. HEMING M, Wiendl H
    Learning multiple sclerosis immunopathogenesis from anti-CD20 therapy.
    Proc Natl Acad Sci U S A. 2023;120:e2221544120.
    PubMed    


  32. MANOUCHEHRI N, Salinas VH, Hussain RZ, Stuve O, et al
    Distinctive transcriptomic and epigenomic signatures of bone marrow-derived myeloid cells and microglia in CNS autoimmunity.
    Proc Natl Acad Sci U S A. 2023;120:e2212696120.
    PubMed     Abstract available


    January 2023
  33. SHINODA K, Li R, Rezk A, Mexhitaj I, et al
    Differential effects of anti-CD20 therapy on CD4 and CD8 T cells and implication of CD20-expressing CD8 T cells in MS disease activity.
    Proc Natl Acad Sci U S A. 2023;120:e2207291120.
    PubMed     Abstract available


  34. JANOSCHKA C, Lindner M, Koppers N, Starost L, et al
    Enhanced pathogenicity of Th17 cells due to natalizumab treatment: Implications for MS disease rebound.
    Proc Natl Acad Sci U S A. 2023;120:e2209944120.
    PubMed     Abstract available


    November 2022
  35. RUBIN DE CELIS MF, Garcia-Martin R, Syed I, Lee J, et al
    PAHSAs reduce cellular senescence and protect pancreatic beta cells from metabolic stress through regulation of Mdm2/p53.
    Proc Natl Acad Sci U S A. 2022;119:e2206923119.
    PubMed     Abstract available


  36. PENG V, Cao S, Trsan T, Bando JK, et al
    Ornithine decarboxylase supports ILC3 responses in infectious and autoimmune colitis through positive regulation of IL-22 transcription.
    Proc Natl Acad Sci U S A. 2022;119:e2214900119.
    PubMed     Abstract available


  37. LIAO Y, Fan L, Bin P, Zhu C, et al
    GABA signaling enforces intestinal germinal center B cell differentiation.
    Proc Natl Acad Sci U S A. 2022;119:e2215921119.
    PubMed     Abstract available


    October 2022
  38. KWIATKOWSKI AJ, Helm EY, Stewart JM, Drashansky TT, et al
    Treatment with an antigen-specific dual microparticle system reverses advanced multiple sclerosis in mice.
    Proc Natl Acad Sci U S A. 2022;119:e2205417119.
    PubMed     Abstract available


  39. BEHRANGI N, Heinig L, Frintrop L, Santrau E, et al
    Siponimod ameliorates metabolic oligodendrocyte injury via the sphingosine-1 phosphate receptor 5.
    Proc Natl Acad Sci U S A. 2022;119:e2204509119.
    PubMed     Abstract available


    September 2022
  40. ZHU Z, Chen X, Wang C, Cheng L, et al
    Novel genes/loci validate the small effect size of ERBB2 in patients with myasthenia gravis.
    Proc Natl Acad Sci U S A. 2022;119:e2207273119.
    PubMed    


  41. CHIA R, Saez-Atienzar S, Drachman DB, Traynor BJ, et al
    Reply to Zhu et al.: Implications of CHRNB1 and ERBB2 in the pathobiology of myasthenia gravis.
    Proc Natl Acad Sci U S A. 2022;119:e2209096119.
    PubMed    


    August 2022
  42. MEYER T, Shimon D, Youssef S, Yankovitz G, et al
    NAD(+) metabolism drives astrocyte proinflammatory reprogramming in central nervous system autoimmunity.
    Proc Natl Acad Sci U S A. 2022;119:e2211310119.
    PubMed     Abstract available


  43. DIEBOLD M, Galli E, Kopf A, Sanderson NSR, et al
    High-dimensional immune profiling identifies a biomarker to monitor dimethyl fumarate response in multiple sclerosis.
    Proc Natl Acad Sci U S A. 2022;119:e2205042119.
    PubMed     Abstract available


  44. GIRDHAR K, Huang Q, Chow IT, Vatanen T, et al
    A gut microbial peptide and molecular mimicry in the pathogenesis of type 1 diabetes.
    Proc Natl Acad Sci U S A. 2022;119:e2120028119.
    PubMed     Abstract available


  45. XIA M, Zhang C, Chen Y, Zhao X, et al
    Transcription factor EB coordinates environmental cues to regulate T regulatory cells' mitochondrial fitness and function.
    Proc Natl Acad Sci U S A. 2022;119:e2205469119.
    PubMed     Abstract available


    July 2022
  46. FRESQUET M, Lockhart-Cairns MP, Rhoden SJ, Jowitt TA, et al
    Structure of PLA2R reveals presentation of the dominant membranous nephropathy epitope and an immunogenic patch.
    Proc Natl Acad Sci U S A. 2022;119:e2202209119.
    PubMed     Abstract available


    June 2022
  47. ZAHOOR I, Suhail H, Datta I, Ahmed ME, et al
    Blood-based untargeted metabolomics in relapsing-remitting multiple sclerosis revealed the testable therapeutic target.
    Proc Natl Acad Sci U S A. 2022;119:e2123265119.
    PubMed     Abstract available


  48. KIM S, Lu HC, Steelman AJ, Li J, et al
    Myeloid caspase-8 restricts RIPK3-dependent proinflammatory IL-1beta production and CD4 T cell activation in autoimmune demyelination.
    Proc Natl Acad Sci U S A. 2022;119:e2117636119.
    PubMed     Abstract available


  49. DAMATO V, Theorell J, Al-Diwani A, Kienzler AK, et al
    Rituximab abrogates aquaporin-4-specific germinal center activity in patients with neuromyelitis optica spectrum disorders.
    Proc Natl Acad Sci U S A. 2022;119:e2121804119.
    PubMed     Abstract available



  50. Correction for Chia et al., Identification of genetic risk loci and prioritization of genes and pathways for myasthenia gravis: a genome-wide association study.
    Proc Natl Acad Sci U S A. 2022;119:e2206754119.
    PubMed    


    May 2022
  51. MANRY J, Bastard P, Gervais A, Le Voyer T, et al
    The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies.
    Proc Natl Acad Sci U S A. 2022;119:e2200413119.
    PubMed     Abstract available


  52. KISSLER S
    Toward a precision medicine approach for autoimmunity.
    Proc Natl Acad Sci U S A. 2022;119:e2204841119.
    PubMed    


    April 2022
  53. YU L, He L, Gan B, Ti R, et al
    Structural insights into sphingosine-1-phosphate receptor activation.
    Proc Natl Acad Sci U S A. 2022;119:e2117716119.
    PubMed     Abstract available


  54. POLICHENI AN, Teh CE, Robbins A, Tuzlak S, et al
    PD-1 cooperates with AIRE-mediated tolerance to prevent lethal autoimmune disease.
    Proc Natl Acad Sci U S A. 2022;119:e2120149119.
    PubMed     Abstract available


  55. POSTIGO-FERNANDEZ J, Firdessa-Fite R, Creusot RJ
    Preclinical evaluation of a precision medicine approach to DNA vaccination in type 1 diabetes.
    Proc Natl Acad Sci U S A. 2022;119:e2110987119.
    PubMed     Abstract available


  56. HWANG D, Seyedsadr MS, Ishikawa LLW, Boehm A, et al
    CSF-1 maintains pathogenic but not homeostatic myeloid cells in the central nervous system during autoimmune neuroinflammation.
    Proc Natl Acad Sci U S A. 2022;119:e2111804119.
    PubMed     Abstract available


    March 2022
  57. SARRAZIN N, Chavret-Reculon E, Bachelin C, Felfli M, et al
    Failed remyelination of the nonhuman primate optic nerve leads to axon degeneration, retinal damages, and visual dysfunction.
    Proc Natl Acad Sci U S A. 2022;119:e2115973119.
    PubMed     Abstract available


  58. GUPTA A, Smith P, Bournazos S, Ravetch JV, et al
    A novel mouse strain optimized for chronic human antibody administration.
    Proc Natl Acad Sci U S A. 2022;119:e2123002119.
    PubMed     Abstract available


  59. CHUNDER R, Weier A, Maurer H, Luber N, et al
    Antibody cross-reactivity between casein and myelin-associated glycoprotein results in central nervous system demyelination.
    Proc Natl Acad Sci U S A. 2022;119:e2117034119.
    PubMed     Abstract available


    February 2022
  60. LIU D, Zhao Z, She Y, Zhang L, et al
    TRIM14 inhibits OPTN-mediated autophagic degradation of KDM4D to epigenetically regulate inflammation.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  61. AMENDT T, Allies G, Nicolo A, El Ayoubi O, et al
    Autoreactive antibodies control blood glucose by regulating insulin homeostasis.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  62. GUO X, Kimura A, Namekata K, Harada C, et al
    ASK1 signaling regulates phase-specific glial interactions during neuroinflammation.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  63. BUCALA RJ
    Targeting fibrocytes in autoimmunity.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed    


  64. CHIA R, Saez-Atienzar S, Murphy N, Chio A, et al
    Identification of genetic risk loci and prioritization of genes and pathways for myasthenia gravis: a genome-wide association study.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    January 2022
  65. WANG Y, Guo L, Yin X, McCarthy EC, et al
    Pathogenic TNF-alpha drives peripheral nerve inflammation in an Aire-deficient model of autoimmunity.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    December 2021
  66. MONAGHAN KL, Aesoph D, Ammer AG, Zheng W, et al
    Tetramerization of STAT5 promotes autoimmune-mediated neuroinflammation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  67. FERNANDO R, Caldera O, Smith TJ
    Therapeutic IGF-I receptor inhibition alters fibrocyte immune phenotype in thyroid-associated ophthalmopathy.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  68. CHANDRAN V, Bermudez ML, Koka M, Chandran B, et al
    Large-scale genomic study reveals robust activation of the immune system following advanced Inner Engineering meditation retreat.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  69. MA Q, Caillier SJ, Muzic S, Wilson MR, et al
    Specific hypomethylation programs underpin B cell activation in early multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  70. LANDEGREN N, Ishii N, Aranda-Guillen M, Gunnarsson HI, et al
    A gene-centric approach to biomarker discovery identifies transglutaminase 1 as an epidermal autoantigen.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  71. VAN DER VAART J, Bosmans L, Sijbesma SF, Knoops K, et al
    Adult mouse and human organoids derived from thyroid follicular cells and modeling of Graves' hyperthyroidism.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  72. IRIKI H, Takahashi H, Wada N, Nomura H, et al
    Peripheral tolerance by Treg via constraining OX40 signal in autoreactive T cells against desmoglein 3, a target antigen in pemphigus.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    November 2021
  73. FORAY AP, Candon S, Hildebrand S, Marquet C, et al
    De novo germline mutation in the dual specificity phosphatase 10 gene accelerates autoimmune diabetes.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  74. CHOI JK, Yu CR, Bing SJ, Jittayasothorn Y, et al
    IL-27-producing B-1a cells suppress neuroinflammation and CNS autoimmune diseases.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  75. VARATHARAJ A, Carare RO, Weller RO, Gawne-Cain M, et al
    Gadolinium enhancement of cranial nerves: Implications for interstitial fluid drainage from brainstem into cranial nerves in humans.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  76. VON HERRATH M, Bonifacio E
    How benign autoimmunity becomes detrimental in type 1 diabetes.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  77. WANG J, Jalali Motlagh N, Wang C, Wojtkiewicz GR, et al
    d-mannose suppresses oxidative response and blocks phagocytosis in experimental neuroinflammation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    October 2021
  78. RAMIREZ DG, Ciccaglione M, Upadhyay AK, Pham VT, et al
    Detecting insulitis in type 1 diabetes with ultrasound phase-change contrast agents.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  79. ANDERSON AM, Landry LG, Alkanani AA, Pyle L, et al
    Human islet T cells are highly reactive to preproinsulin in type 1 diabetes.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  80. MANOUCHEHRI N, Stuve O
    Choroid plexus volumetrics and brain inflammation in multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


    September 2021
  81. YANG K, O'Cearbhaill ED, Liu SS, Zhou A, et al
    A therapeutic convection-enhanced macroencapsulation device for enhancing beta cell viability and insulin secretion.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  82. FLEISCHER V, Gonzalez-Escamilla G, Ciolac D, Albrecht P, et al
    Translational value of choroid plexus imaging for tracking neuroinflammation in mice and humans.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  83. HARTLEHNERT M, Borsch AL, Li X, Burmeister M, et al
    Bcl6 controls meningeal Th17-B cell interaction in murine neuroinflammation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    August 2021
  84. LAROCHELLE C, Wasser B, Jamann H, Loffel JT, et al
    Pro-inflammatory T helper 17 directly harms oligodendrocytes in neuroinflammation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  85. SINGH KD, Jara ZP, Harford T, Saha PP, et al
    Novel allosteric ligands of the angiotensin receptor AT1R as autoantibody blockers.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  86. LONGBRAKE EE, Hafler DA
    (23)Na imaging: Worth its salt for understanding multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  87. JING X, Yao Y, Wu D, Hong H, et al
    IFP35 family proteins promote neuroinflammation and multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    July 2021
  88. JUUL-MADSEN K, Troldborg A, Wittenborn TR, Axelsen MG, et al
    Characterization of DNA-protein complexes by nanoparticle tracking analysis and their association with systemic lupus erythematosus.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available



  89. Correction for Ostkamp et al., Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  90. BRYAN CM, Rocklin GJ, Bick MJ, Ford A, et al
    Computational design of a synthetic PD-1 agonist.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  91. HUHN K, Linz P, Pemsel F, Michalke B, et al
    Skin sodium is increased in male patients with multiple sclerosis and related animal models.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  92. COLOMBO E, Triolo D, Bassani C, Bedogni F, et al
    Dysregulated copper transport in multiple sclerosis may cause demyelination via astrocytes.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    June 2021
  93. PATERGNANI S, Bonora M, Ingusci S, Previati M, et al
    Antipsychotic drugs counteract autophagy and mitophagy in multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  94. PYFROM S, Paneru B, Knox JJ, Cancro MP, et al
    The dynamic epigenetic regulation of the inactive X chromosome in healthy human B cells is dysregulated in lupus patients.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    May 2021
  95. HUANG YS, Tseng WY, Clanchy FIL, Topping LM, et al
    Pharmacological modulation of T cell immunity results in long-term remission of autoimmune arthritis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  96. UMEDA M, Yoshida N, Hisada R, Burbano C, et al
    ADAM9 enhances Th17 cell differentiation and autoimmunity by activating TGF-beta1.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  97. BARNES SE, Han MH
    CD317 puts the brakes on dendritic cell trafficking to the CNS.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


    April 2021
  98. ZHELEZNYAKOVA GY, Piket E, Needhamsen M, Hagemann-Jensen M, et al
    Small noncoding RNA profiling across cellular and biofluid compartments and their implications for multiple sclerosis immunopathology.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available



  99. Correction to Supporting Information for Luo et al., The conserved autoimmune-disease risk gene TMEM39A regulates lysosome dynamics.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


    March 2021
  100. RONIN E, Pouchy C, Khosravi M, Hilaire M, et al
    Tissue-restricted control of established central nervous system autoimmunity by TNF receptor 2-expressing Treg cells.
    Proc Natl Acad Sci U S A. 2021;118:e2014043118.
    PubMed     Abstract available


  101. SUN T, Yu Y, Wu X, Acevedo A, et al
    Decoupling expression and editing preferences of ADAR1 p150 and p110 isoforms.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  102. RAVENEY BJE, Sato W, Takewaki D, Zhang C, et al
    Involvement of cytotoxic Eomes-expressing CD4(+) T cells in secondary progressive multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  103. TOROK O, Schreiner B, Schaffenrath J, Tsai HC, et al
    Pericytes regulate vascular immune homeostasis in the CNS.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  104. WANG MY, Dean ED, Quittner-Strom E, Zhu Y, et al
    Glucagon blockade restores functional beta-cell mass in type 1 diabetic mice and enhances function of human islets.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    February 2021
  105. TEO W, Caprariello AV, Morgan ML, Luchicchi A, et al
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