Retrieve available abstracts of 66 articles: HTML format
Single Articles
May 2025
KIM EJ, Wang Y, Chen YL, Ma M, et al CARM1-mediated MAP2K4 methylation potentiates the oncogenic functions of MAP2K4
and constitutes a targetable dependency in triple-negative breast cancer.
Cancer Res. 2025 May 29. doi: 10.1158/0008-5472.CAN-24-3476. PubMedAbstract available
ELKHOLI IE, Robert A, Malouf C, Wu JL, et al Targeting the Dependence on PIK3C3-mTORC1 Signaling in Dormancy-Prone Breast
Cancer Cells Blunts Metastasis Initiation.
Cancer Res. 2025 May 15:OF1-OF20. doi: 10.1158/0008-5472.CAN-23-2654. PubMedAbstract available
GOHARI Z, Stojanovic L, Rassool FV Combining STING Agonists with PARP Inhibitors Mounts an NK-Dependent Defense
against Therapy-Resistant Breast Cancer.
Cancer Res. 2025;85:1747-1749. PubMedAbstract available
April 2025
LUTZ C, Chao X, de Klein B, Bhin J, et al Large-Scale Characterization of Orthotopic Cell Line-Derived Xenografts
Identifies TGF-beta Signaling as a Key Regulator of Breast Cancer Morphology and
Aggressiveness.
Cancer Res. 2025 Apr 30. doi: 10.1158/0008-5472.CAN-24-2022. PubMedAbstract available
SOUTO EP, Gong P, Landua JD, Rajaram Srinivasan R, et al Lineage Tracing and Single-Cell RNA Sequencing Reveal a Common Transcriptional
State in Breast Cancer Tumor-Initiating Cells Characterized by IFN/STAT1
Activity.
Cancer Res. 2025;85:1390-1409. PubMedAbstract available
DOMMER AP, Kumarasamy V, Wang J, O'Connor TN, et al Tumor Suppressors Condition Differential Responses to the Selective CDK2
Inhibitor BLU-222.
Cancer Res. 2025;85:1310-1326. PubMedAbstract available
March 2025
PEDRETTI F, Abdalfttah M, Pellegrino B, Mateo F, et al Harnessing STING Signaling and Natural Killer Cells overcomes PARP Inhibitor
Resistance in Homologous Recombination Deficient Breast Cancer.
Cancer Res. 2025 Mar 11. doi: 10.1158/0008-5472.CAN-24-2531. PubMedAbstract available
February 2025
SUN Z, Li Z, Wei Y, Xu L, et al SMARCA4 Inhibits Breast Cancer Progression and Metastasis through RHOA
Suppression.
Cancer Res. 2025 Feb 24. doi: 10.1158/0008-5472.CAN-24-2801. PubMedAbstract available
BADO IL Deterministic Role of FOXF2 in Organ-Specific Macrometastasis Transition.
Cancer Res. 2025;85:639-641. PubMedAbstract available
ZHOU S, Zhang Y, Belmar J, Hou C, et al Stabilization of RUNX1 Induced by O-GlcNAcylation Promotes PDGF-BB-Mediated
Resistance to CDK4/6 Inhibitors in Breast Cancer.
Cancer Res. 2025 Feb 12. doi: 10.1158/0008-5472.CAN-24-2492. PubMedAbstract available
IPPOLITOV D, Lin YH, Spence J, Glogowska A, et al The Brain-Penetrant Pan ErbB Inhibitor Poziotinib Effectively Targets HER2+
Breast Cancer Brain Metastases.
Cancer Res. 2025 Feb 11. doi: 10.1158/0008-5472.CAN-24-1793. PubMedAbstract available
METGE BJ, Williams L, Swain CA, Hinshaw DC, et al Ribosomal RNA Biosynthesis Functionally Programs Tumor-Associated Macrophages to
Support Breast Cancer Progression.
Cancer Res. 2025 Feb 4. doi: 10.1158/0008-5472.CAN-24-0707. PubMedAbstract available
MADORSKY ROWDO FP, Martini R, Ackermann SE, Tang CP, et al Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast
Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1
Inhibition.
Cancer Res. 2025;85:551-566. PubMedAbstract available
TREMBATH HE, Spanheimer PM In Search of Representative Translational Cancer Model Systems.
Cancer Res. 2025;85:407-409. PubMedAbstract available
January 2025
TABET I, Orhan E, Candiello E, Fenou L, et al Replication-Poison Treatment in BRCA1-Deficient Breast Cancer Causes MRE11
Over-Resection that Induces Single-Stranded DNA Accumulation and Mitotic
Catastrophe.
Cancer Res. 2025 Jan 29. doi: 10.1158/0008-5472.CAN-24-1404. PubMedAbstract available
VAN ALSTEN SC, Love MI, Calhoun BC, Butler EN, et al Genomic Analysis Reveals Racial and Age-Related Differences in the Somatic
Landscape of Breast Cancer and the Association with Socioeconomic Factors.
Cancer Res. 2025 Jan 29. doi: 10.1158/0008-5472.CAN-24-1788. PubMedAbstract available
DEY P, Brisken C Breaking the Rhythm: Harnessing the Menstrual Cycle for Better Chemotherapy.
Cancer Res. 2025 Jan 29. doi: 10.1158/0008-5472.CAN-25-0335. PubMedAbstract available
VISAL TH, Bayraktar R, den Hollander P, Attathikhun MA, et al Accumulation of CD38 in Hybrid Epithelial/Mesenchymal Cells Promotes Immune
Remodeling and Metastasis in Breast Cancer.
Cancer Res. 2025 Jan 24:OF1-OF18. doi: 10.1158/0008-5472.CAN-24-0400. PubMedAbstract available
PIERRO EW, Cottam MA, An H, Lehmann BD, et al Comparison of Lean, Obese, and Weight Loss Models Reveals TREM2 Deficiency
Attenuates Breast Cancer Growth Uniquely in Lean Mice and Alters Clonal T Cell
Populations.
Cancer Res. 2025 Jan 22. doi: 10.1158/0008-5472.CAN-24-3511. PubMedAbstract available
GAO L, Huang J, Xia J, Zhao P, et al SNHG17 Reprograms Energy Metabolism of Breast Cancer by Activating Mitochondrial
DNAs Transcription.
Cancer Res. 2025 Jan 22. doi: 10.1158/0008-5472.CAN-24-1271. PubMedAbstract available
TAU S, Chamberlin MD, Yang H, Marotti JD, et al Oxidative Phosphorylation is a Metabolic Vulnerability of Endocrine
Therapy-Tolerant Persister Cells in ER+ Breast Cancer.
Cancer Res. 2025 Jan 9. doi: 10.1158/0008-5472.CAN-24-1204. PubMedAbstract available
December 2024
CHEN SY, He PL, Lu LY, Lin MC, et al ST6GAL1-Mediated Sialylation of PECAM-1 Promotes a Transcellular Diapedesis-Like
Process that Directs Lung Tropism of Metastatic Breast Cancer.
Cancer Res. 2024 Dec 30. doi: 10.1158/0008-5472.CAN-24-1550. PubMedAbstract available
CHEN F, Ding K, Priedigkeit N, Elangovan A, et al Correction: Single-Cell Transcriptomic Heterogeneity in Invasive Ductal and
Lobular Breast Cancer Cells.
Cancer Res. 2024;84:4298. PubMed
FENG JR, Li X, Han C, Chang Y, et al C-Reactive Protein Induces Immunosuppression by Activating FcgammaR2B in Pulmonary
Macrophages to Promote Lung Metastasis.
Cancer Res. 2024;84:4184-4198. PubMedAbstract available
SHI W, Li L, Zhao H, Li Z, et al Targeting SHCBP1 Inhibits Tumor Progression by Restoring Ciliogenesis in Ductal
Carcinoma.
Cancer Res. 2024;84:4156-4172. PubMedAbstract available
BHAGWAT SV, Mur C, Vandekopple M, Zhao B, et al Imlunestrant is an Oral, Brain-Penetrant Selective Estrogen Receptor Degrader
with Potent Antitumor Activity in ESR1 Wildtype and Mutant Breast Cancer.
Cancer Res. 2024 Dec 9. doi: 10.1158/0008-5472.CAN-24-2608. PubMedAbstract available
FRIELING JS, Lynch CC Tales of Cancer-Induced Bone Disease from the Senescent Osteocyte Crypt.
Cancer Res. 2024;84:3917-3918. PubMedAbstract available
November 2024
JIANG WJ, Zhou TH, Huang HJ, Li LS, et al Breast Cancer Subtype-Specific Organotropism is Dictated by FOXF2-Regulated
Metastatic Dormancy and Recovery.
Cancer Res. 2024 Nov 26. doi: 10.1158/0008-5472.CAN-24-0479. PubMedAbstract available
ZENG W, Zhang R, Huang P, Chen M, et al Ferroptotic Neutrophils Induce Immunosuppression and Chemoresistance in Breast
Cancer.
Cancer Res. 2024 Nov 12. doi: 10.1158/0008-5472.CAN-24-1941. PubMedAbstract available
SHEA A, Eyal-Lubling Y, Guerrero-Romero D, Manzano Garcia R, et al Modeling Drug Responses and Evolutionary Dynamics using Patient-Derived
Xenografts Reveals Precision Medicine Strategies for Triple Negative Breast
Cancer.
Cancer Res. 2024 Nov 8. doi: 10.1158/0008-5472.CAN-24-1703. PubMedAbstract available
October 2024
KUETT L, Bollhagen A, Tietscher S, Sobottka B, et al Distant Metastases of Breast Cancer Resemble Primary Tumors in Cancer Cell
Composition but Differ in Immune Cell Phenotypes.
Cancer Res. 2024 Oct 22. doi: 10.1158/0008-5472.CAN-24-1211. PubMedAbstract available
CACKOWSKI FC, Korkaya H Breast Cancer Disseminated Tumor Cells: Do They Stay and Fight or Run and Hide?
Cancer Res. 2024;84:3319-3321. PubMedAbstract available
PAREJA F, Dopeso H, Wang YK, Gazzo AM, et al A Genomics-Driven Artificial Intelligence-Based Model Classifies Breast Invasive
Lobular Carcinoma and Discovers CDH1 Inactivating Mechanisms.
Cancer Res. 2024;84:3478-3489. PubMedAbstract available
FALCONE M, Salhia B, Hughes Halbert C, Roussos Torres ET, et al Impact of Structural Racism and Social Determinants of Health on Disparities in
Breast Cancer Mortality.
Cancer Res. 2024 Oct 2. doi: 10.1158/0008-5472.CAN-24-1359. PubMedAbstract available
GEMMA C, Lai CF, Singh AK, Belfiore A, et al Induction of the TEAD Co-activator VGLL1 by Estrogen Receptor-Targeted Therapy
Drives Resistance in Breast Cancer.
Cancer Res. 2024 Oct 2. doi: 10.1158/0008-5472.CAN-24-0013. PubMedAbstract available
PURDY SC, Ford HL Remembering Hypoxia: Uncovering the Long-Term Effects of Transient Oxygen
Deprivation on IFN Signaling and Progression of Breast Cancer.
Cancer Res. 2024;84:3125-3127. PubMedAbstract available
GONZALEZ ME, Brophy B, Eido A, Leonetti AE, et al CCN6 Suppresses Metaplastic Breast Carcinoma by Antagonizing Wnt/beta-Catenin
Signaling to Inhibit EZH2-Driven EMT.
Cancer Res. 2024;84:3235-3249. PubMedAbstract available
SHIN SY, Chew NJ, Ghomlaghi M, Chueh AC, et al Integrative Modeling of Signaling Network Dynamics Identifies Cell Type-Selective
Therapeutic Strategies for FGFR4-Driven Cancers.
Cancer Res. 2024;84:3296-3309. PubMedAbstract available
September 2024
KAUR J, Adhikari M, Sabol HM, Anloague A, et al Single-cell Transcriptomic Analysis Identifies Senescent Osteocytes that Trigger
Bone Destruction in Breast Cancer Metastasis.
Cancer Res. 2024 Sep 23. doi: 10.1158/0008-5472.CAN-24-0857. PubMedAbstract available
LUO M, Shen N, Shang L, Fang Z, et al Simultaneous Targeting of NQO1 and SOD1 Eradicates Breast Cancer Stem Cells via
Mitochondrial Futile Redox Cycling.
Cancer Res. 2024 Sep 12. doi: 10.1158/0008-5472.CAN-24-0800. PubMedAbstract available
GILKES DM, Chaturvedi P, Bajpai S, Wong CC, et al Retraction: Collagen Prolyl Hydroxylases Are Essential for Breast Cancer
Metastasis.
Cancer Res. 2024;84:2927. PubMed
SAMANTA D, Park Y, Andrabi SA, Shelton LM, et al Retraction: PHGDH Expression Is Required for Mitochondrial Redox Homeostasis,
Breast Cancer Stem Cell Maintenance, and Lung Metastasis.
Cancer Res. 2024;84:2926. PubMed
CONNER SJ, Borges HB, Guarin JR, Gerton TJ, et al Obesity Induces Temporally Regulated Alterations in the Extracellular Matrix That
Drive Breast Tumor Invasion and Metastasis.
Cancer Res. 2024;84:2761-2775. PubMedAbstract available
August 2024
ZHOU Z, Si Y, Zhang J, Chen K, et al A Dual-Payload Antibody-Drug Conjugate Targeting CD276/B7-H3 Elicits Cytotoxicity
and Immune Activation in Triple-Negative Breast Cancer.
Cancer Res. 2024 Aug 26. doi: 10.1158/0008-5472.CAN-23-4099. PubMedAbstract available
LI YW, Dai LJ, Wu XR, Zhao S, et al Molecular Characterization and Classification of HER2-Positive Breast Cancer
Inform Tailored Therapeutic Strategies.
Cancer Res. 2024 Aug 26. doi: 10.1158/0008-5472.CAN-23-4066. PubMedAbstract available
LEWIS MW, King CM, Wisniewska K, Regner MJ, et al CRISPR Screening of Transcribed Super-Enhancers Identifies Drivers of
Triple-Negative Breast Cancer Progression.
Cancer Res. 2024 Aug 26. doi: 10.1158/0008-5472.CAN-23-3995. PubMedAbstract available
LI M, Lulla AR, Wang Y, Tsavachidis S, et al Low Molecular Weight Cyclin E Confers a Vulnerability to PKMYT1 Inhibition in
Triple-Negative Breast Cancer.
Cancer Res. 2024 Aug 26. doi: 10.1158/0008-5472.CAN-23-4130. PubMedAbstract available
HEATH J, Mirabelli C, Annis MG, Sabourin V, et al The Neurodevelopmental Protein POGZ Suppresses Metastasis in Triple Negative
Breast Cancer by Attenuating TGFbeta Signaling.
Cancer Res. 2024 Aug 13. doi: 10.1158/0008-5472.CAN-23-3887. PubMedAbstract available
BUSHNELL GG, Sharma D, Wilmot HC, Zheng M, et al Natural Killer Cell Regulation of Breast Cancer Stem Cells Mediates Metastatic
Dormancy.
Cancer Res. 2024 Aug 6. doi: 10.1158/0008-5472.CAN-24-0030. PubMedAbstract available
July 2024
WANG X, Qu Y, Xu Q, Jiang Z, et al NQO1 Triggers Neutrophil Recruitment and NET formation to Drive Lung Metastasis
of Invasive Breast Cancer.
Cancer Res. 2024 Jul 29. doi: 10.1158/0008-5472.CAN-24-0291. PubMedAbstract available
HSU WJ, Chiang MC, Chao YC, Chang YC, et al Arginine methylation of DDX3 by PRMT1 mediates mitochondrial homeostasis to
promote breast cancer metastasis.
Cancer Res. 2024 Jul 23. doi: 10.1158/0008-5472.CAN-23-3829. PubMedAbstract available
PIEMONTE KM, Ingles NN, Weber Bonk KL, Valentine MJ, et al Targeting YES1 Disrupts Mitotic Fidelity and Potentiates the Response to Taxanes
in Triple-Negative Breast Cancer.
Cancer Res. 2024 Jul 22. doi: 10.1158/0008-5472.CAN-23-2558. PubMedAbstract available
HUANG YZ, Sang MY, Xi PW, Xu RX, et al FANCI Inhibition Induces PARP1 Redistribution to Enhance the Efficacy of PARP
Inhibitors in Breast Cancer.
Cancer Res. 2024 Jul 22. doi: 10.1158/0008-5472.CAN-23-2738. PubMedAbstract available
HILLIS AL, Martin TD, Manchester HE, Hogstrom J, et al Targeting Cholesterol Biosynthesis with Statins Synergizes with AKT Inhibitors in
Triple-Negative Breast Cancer.
Cancer Res. 2024 Jul 18. doi: 10.1158/0008-5472.CAN-24-0970. PubMedAbstract available
IRIONDO O, Mecenas D, Li Y, Chin CR, et al Hypoxic Memory Mediates Prolonged Tumor Intrinsic Type I Interferon Suppression
to Promote Breast Cancer Progression.
Cancer Res. 2024 Jul 11. doi: 10.1158/0008-5472.CAN-23-2028. PubMedAbstract available
LEE G, Wong C, Cho A, West JJ, et al E-cadherin Induces Serine Synthesis to Support Progression and Metastasis of
Breast Cancer.
Cancer Res. 2024 Jul 3. doi: 10.1158/0008-5472.CAN-23-3082. PubMedAbstract available
June 2024
MENEGOLLO M, Bentham RB, Henriques T, Ng SQ, et al Multi-State Gene Cluster Switches Determine the Adaptive Mitochondrial And
Metabolic Landscape of Breast Cancer.
Cancer Res. 2024 Jun 26. doi: 10.1158/0008-5472.CAN-23-3172. PubMedAbstract available
XU G, Huang R, Wumaier R, Lyu J, et al Proteomic Profiling of Serum Extracellular Vesicles Identifies Diagnostic
Signatures and Therapeutic Targets in Breast Cancer.
Cancer Res. 2024 Jun 20. doi: 10.1158/0008-5472.CAN-23-3998. PubMedAbstract available
TUCKER JB, Carlsen CL, Scribano CM, Pattaswamy SM, et al CENP-E inhibition induces chromosomal instability and synergizes with diverse
microtubule-targeting agents in breast cancer.
Cancer Res. 2024 Jun 4. doi: 10.1158/0008-5472.CAN-23-3332. PubMedAbstract available
SUN X, Verma SP, Jia G, Wang X, et al Case-Case Genome-Wide Analyses Identify Subtype-Informative Variants that Confer
Risk for Breast Cancer.
Cancer Res. 2024 Jun 4. doi: 10.1158/0008-5472.CAN-23-3854. PubMedAbstract available
ELEMENTO O How Artificial Intelligence Unravels the Complex Web of Cancer Drug Response.
Cancer Res. 2024;84:1745-1746. PubMedAbstract available
May 2024
HUANG MY, Hu SY, Dong J, Deng L, et al The DRAP1/DR1 Repressor Complex Increases mTOR Activity to Promote Progression
and Confer Everolimus Sensitivity in Triple-Negative Breast Cancer.
Cancer Res. 2024 May 15. doi: 10.1158/0008-5472.CAN-23-2781. PubMedAbstract available
April 2024
XIA J, Zhang L, Peng X, Tu J, et al IL1R2 blockade alleviates immunosuppression and potentiates anti-PD-1 efficacy in
triple-negative breast cancer.
Cancer Res. 2024 Apr 24. doi: 10.1158/0008-5472.CAN-23-3429. PubMedAbstract available
ZHENG SM, Feng YC, Zhu Q, Li RQ, et al MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast
Cancer.
Cancer Res. 2024 Apr 9:OF1-OF15. doi: 10.1158/0008-5472.CAN-23-3046. PubMedAbstract available
March 2024
ZHANG M, Zhou K, Wang Z, Liu T, et al A subpopulation of luminal progenitors secretes pleiotrophin to promote
angiogenesis and metastasis in inflammatory breast cancer.
Cancer Res. 2024 Mar 20. doi: 10.1158/0008-5472.CAN-23-2640. PubMedAbstract available
QIU Y, Wang X, Sun Y, Jin T, et al ACSL4-mediated membrane phospholipid remodeling induces integrin beta1 activation to
facilitate triple-negative breast cancer metastasis.
Cancer Res. 2024 Mar 12. doi: 10.1158/0008-5472.CAN-23-2491. PubMedAbstract available