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  Breast Cancer

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Articles published in N Engl J Med

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Single Articles


    August 2020
  1. O'DRISCOLL L
    When E-Cadherin Becomes Unstuck in Cancer.
    N Engl J Med. 2020;383:871-873.
    PubMed    


    July 2020
  2. SPRING LM, Specht MC, Jimenez RB, Isakoff SJ, et al
    Case 22-2020: A 62-Year-Old Woman with Early Breast Cancer during the Covid-19 Pandemic.
    N Engl J Med. 2020 Jul 1. doi: 10.1056/NEJMcpc2002422.
    PubMed    


    June 2020
  3. SCHMID P, Dent R, O'Shaughnessy J
    Pembrolizumab for Early Triple-Negative Breast Cancer. Reply.
    N Engl J Med. 2020;382:e108.
    PubMed    


  4. CETIN B, Gumusay O
    Pembrolizumab for Early Triple-Negative Breast Cancer.
    N Engl J Med. 2020;382:e108.
    PubMed    


  5. WINER EP
    Therapy for HER2-Positive Metastatic Breast Cancer. Reply.
    N Engl J Med. 2020;382:e98.
    PubMed    


  6. DEKKER TJA
    Therapy for HER2-Positive Metastatic Breast Cancer.
    N Engl J Med. 2020;382:e98.
    PubMed    


  7. SLAMON DJ, Jerusalem G
    Ribociclib plus Fulvestrant in Advanced Breast Cancer. Reply.
    N Engl J Med. 2020;382:e85.
    PubMed    


  8. HINDIE E
    Ribociclib plus Fulvestrant in Advanced Breast Cancer.
    N Engl J Med. 2020;382:e85.
    PubMed    


    April 2020
  9. MOLIERE S, Mathelin C
    The Cowden Syndrome.
    N Engl J Med. 2020;382:e29.
    PubMed    


    March 2020
  10. BAKKER MF, de Lange SV, van Gils CH
    MRI Screening in Women with Dense Breasts. Reply.
    N Engl J Med. 2020;382:1284.
    PubMed    


  11. WELCH HG, Zahl PH
    MRI Screening in Women with Dense Breasts.
    N Engl J Med. 2020;382:1283-1284.
    PubMed    


  12. GORDON PB
    MRI Screening in Women with Dense Breasts.
    N Engl J Med. 2020;382:1283.
    PubMed    


  13. AUTIER P
    MRI Screening in Women with Dense Breasts.
    N Engl J Med. 2020;382:1282.
    PubMed    


  14. SHARMA V
    MRI Screening in Women with Dense Breasts.
    N Engl J Med. 2020;382:1282.
    PubMed    


    February 2020
  15. SCHMID P, Cortes J, Pusztai L, McArthur H, et al
    Pembrolizumab for Early Triple-Negative Breast Cancer.
    N Engl J Med. 2020;382:810-821.
    PubMed     Abstract available


  16. ISAKOFF SJ, Lehman CD, Shannon KM, Basnet KM, et al
    Case 7-2020: A 52-Year-Old Man with a Mass in the Left Breast.
    N Engl J Med. 2020;382:856-864.
    PubMed    


  17. SHARMA P
    Major Strides in HER2 Blockade for Metastatic Breast Cancer.
    N Engl J Med. 2020;382:669-671.
    PubMed    


    January 2020
  18. PINKERTON JV
    Hormone Therapy for Postmenopausal Women.
    N Engl J Med. 2020;382:446-455.
    PubMed    


  19. HAYES DF
    Progress in the Treatment of Breast Cancer. Reply.
    N Engl J Med. 2020;382:e4.
    PubMed    


  20. KONNER M
    Progress in the Treatment of Breast Cancer.
    N Engl J Med. 2020;382:e4.
    PubMed    


    December 2019

  21. Tucatinib, Trastuzumab, and Capecitabine for HER2-Positive Metastatic Breast Cancer.
    N Engl J Med. 2019 Dec 27. doi: 10.1056/NEJMx190039.
    PubMed    


  22. SLAMON DJ, Neven P, Chia S, Fasching PA, et al
    Overall Survival with Ribociclib plus Fulvestrant in Advanced Breast Cancer.
    N Engl J Med. 2019 Dec 11. doi: 10.1056/NEJMoa1911149.
    PubMed     Abstract available


  23. MURTHY RK, Loi S, Okines A, Paplomata E, et al
    Tucatinib, Trastuzumab, and Capecitabine for HER2-Positive Metastatic Breast Cancer.
    N Engl J Med. 2019 Dec 11. doi: 10.1056/NEJMoa1914609.
    PubMed     Abstract available


  24. MODI S, Saura C, Yamashita T, Park YH, et al
    Trastuzumab Deruxtecan in Previously Treated HER2-Positive Breast Cancer.
    N Engl J Med. 2019 Dec 11. doi: 10.1056/NEJMoa1914510.
    PubMed     Abstract available


    November 2019
  25. LONGO DL
    Detecting Breast Cancer in Women with Dense Breasts.
    N Engl J Med. 2019;381:2169-2170.
    PubMed    


  26. BAKKER MF, de Lange SV, Pijnappel RM, Mann RM, et al
    Supplemental MRI Screening for Women with Extremely Dense Breast Tissue.
    N Engl J Med. 2019;381:2091-2102.
    PubMed     Abstract available


    October 2019
  27. IM SA, Lu YS, Tripathy D
    Ribociclib and Endocrine Therapy in Breast Cancer. Reply.
    N Engl J Med. 2019;381:1592-1593.
    PubMed    


  28. ROCCA A, Melegari E, Palleschi M
    Ribociclib and Endocrine Therapy in Breast Cancer.
    N Engl J Med. 2019;381:1592.
    PubMed    


    September 2019
  29. SPARANO JA
    Clinical and Genomic Risk in Adjuvant Therapy for Breast Cancer. Reply.
    N Engl J Med. 2019;381:1290-1291.
    PubMed    


  30. GIORGI ROSSI P, Lebeau A, Schunemann HJ
    Clinical and Genomic Risk in Adjuvant Therapy for Breast Cancer.
    N Engl J Med. 2019;381:1289-1290.
    PubMed    


  31. SCHVARTSMAN G, Kaliks RA
    Clinical and Genomic Risk in Adjuvant Therapy for Breast Cancer.
    N Engl J Med. 2019;381:1289-1291.
    PubMed    


  32. SALINAS-BOTRAN A, Guarin-Corredor MJ
    Orbital Metastasis in Breast Cancer.
    N Engl J Med. 2019;381:e26.
    PubMed    


  33. HAYES DF
    HER2 and Breast Cancer - A Phenomenal Success Story.
    N Engl J Med. 2019 Sep 10. doi: 10.1056/NEJMcibr1909386.
    PubMed    


    August 2019
  34. ANDRE F, Mills D, Taran T
    Alpelisib for PIK3CA-Mutated Advanced Breast Cancer. Reply.
    N Engl J Med. 2019;381:687.
    PubMed    


  35. COPUR MS, Jonglertham P
    Alpelisib for PIK3CA-Mutated Advanced Breast Cancer.
    N Engl J Med. 2019;381:686-687.
    PubMed    


  36. PARK J, Shin SW
    Alpelisib for PIK3CA-Mutated Advanced Breast Cancer.
    N Engl J Med. 2019;381:686.
    PubMed    


    July 2019
  37. RUGO HS
    Achieving Improved Survival Outcomes in Advanced Breast Cancer.
    N Engl J Med. 2019;381:371-372.
    PubMed    


    June 2019
  38. HUNTER DJ, Longo DL
    The Precision of Evidence Needed to Practice "Precision Medicine".
    N Engl J Med. 2019;380:2472-2474.
    PubMed    


  39. BARDIA A, Mayer IA, Kalinsky K
    Sacituzumab Govitecan-hziy in Triple-Negative Breast Cancer. Reply.
    N Engl J Med. 2019;380:2382.
    PubMed    


  40. OZAKI Y, Masuda J, Takano T
    Sacituzumab Govitecan-hziy in Triple-Negative Breast Cancer.
    N Engl J Med. 2019;380:2382.
    PubMed    



  41. Overall Survival with Fulvestrant plus Anastrozole in Metastatic Breast Cancer.
    N Engl J Med. 2019;380:2282.
    PubMed    


  42. IM SA, Lu YS, Bardia A, Harbeck N, et al
    Overall Survival with Ribociclib plus Endocrine Therapy in Breast Cancer.
    N Engl J Med. 2019 Jun 4. doi: 10.1056/NEJMoa1903765.
    PubMed     Abstract available


  43. SPARANO JA, Gray RJ, Ravdin PM, Makower DF, et al
    Clinical and Genomic Risk to Guide the Use of Adjuvant Therapy for Breast Cancer.
    N Engl J Med. 2019 Jun 3. doi: 10.1056/NEJMoa1904819.
    PubMed     Abstract available


    May 2019
  44. ANDRE F, Ciruelos E, Rubovszky G, Campone M, et al
    Alpelisib for PIK3CA-Mutated, Hormone Receptor-Positive Advanced Breast Cancer.
    N Engl J Med. 2019;380:1929-1940.
    PubMed     Abstract available


    April 2019
  45. WALKER SP
    The ROC Curve Redefined - Optimizing Sensitivity (and Specificity) to the Lived Reality of Cancer.
    N Engl J Med. 2019;380:1594-1595.
    PubMed    


  46. PALLOK K, De Maio F, Ansell DA
    Structural Racism - A 60-Year-Old Black Woman with Breast Cancer.
    N Engl J Med. 2019;380:1489-1493.
    PubMed    


  47. NARDI V
    Case 35-2018: A Woman with Back Pain and a Remote History of Breast Cancer. Reply.
    N Engl J Med. 2019;380.
    PubMed    


  48. FOULKES WD, Witkowski L
    Case 35-2018: A Woman with Back Pain and a Remote History of Breast Cancer.
    N Engl J Med. 2019;380.
    PubMed    


    March 2019
  49. MEHTA RS, Barlow WE, Albain KS, Vandenberg TA, et al
    Overall Survival with Fulvestrant plus Anastrozole in Metastatic Breast Cancer.
    N Engl J Med. 2019;380:1226-1234.
    PubMed     Abstract available


  50. SCHMID P, Chui SY, Emens LA
    Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer. Reply.
    N Engl J Med. 2019;380:987-988.
    PubMed    


  51. ALTUNDAG K
    Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer.
    N Engl J Med. 2019;380:986-987.
    PubMed    


  52. O'SULLIVAN H, Collins D, O'Reilly S
    Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer.
    N Engl J Med. 2019;380:986.
    PubMed    


  53. AKTAS BY, Taban H, Aksoy S
    Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer.
    N Engl J Med. 2019;380:985-986.
    PubMed    


    February 2019
  54. MCCAW ZR, Vassy JL, Wei LJ
    Palbociclib and Fulvestrant in Breast Cancer.
    N Engl J Med. 2019;380:796.
    PubMed    


  55. TURNER NC, Huang X, Cristofanilli M
    Palbociclib and Fulvestrant in Breast Cancer. Reply.
    N Engl J Med. 2019;380:797.
    PubMed    


  56. NAIK RD, Batra A, Gupta VG
    Palbociclib and Fulvestrant in Breast Cancer.
    N Engl J Med. 2019;380:796.
    PubMed    


  57. BARDIA A, Mayer IA, Vahdat LT, Tolaney SM, et al
    Sacituzumab Govitecan-hziy in Refractory Metastatic Triple-Negative Breast Cancer.
    N Engl J Med. 2019;380:741-751.
    PubMed     Abstract available


  58. PROWELL TM, Beaver JA, Pazdur R
    Residual Disease after Neoadjuvant Therapy - Developing Drugs for High-Risk Early Breast Cancer.
    N Engl J Med. 2019;380:612-615.
    PubMed    


  59. HAYES DF
    Further Progress for Patients with Breast Cancer.
    N Engl J Med. 2019;380:676-677.
    PubMed    



  60. Lymphedema after Breast Cancer Treatment.
    N Engl J Med. 2019;380:694.
    PubMed    


  61. JINDEEL A
    Lymphedema after Breast Cancer Treatment.
    N Engl J Med. 2019;380:694.
    PubMed    


    January 2019
  62. DEFILIPPIS EM, Nohria A, Burstein HJ, Doyle LA, et al
    A Breath-Taking Diagnosis.
    N Engl J Med. 2019;380:81-87.
    PubMed    


    December 2018

  63. Ribociclib as First-Line Therapy for HR-Positive, Advanced Breast Cancer.
    N Engl J Med. 2018;379:2582.
    PubMed    


  64. VON MINCKWITZ G, Huang CS, Mano MS, Loibl S, et al
    Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer.
    N Engl J Med. 2018 Dec 5. doi: 10.1056/NEJMoa1814017.
    PubMed     Abstract available


    November 2018
  65. ROCKSON SG
    Lymphedema after Breast Cancer Treatment.
    N Engl J Med. 2018;379:1937-1944.
    PubMed    


  66. BARDIA A, Hovnanian MD, Brachtel EF, Nardi V, et al
    Case 35-2018: A 68-Year-Old Woman with Back Pain and a Remote History of Breast Cancer.
    N Engl J Med. 2018;379:1946-1953.
    PubMed    


    October 2018
  67. CHLEBOWSKI RT, Pan K
    Adjuvant Endocrine Therapy for Premenopausal Breast Cancer.
    N Engl J Med. 2018;379:1684.
    PubMed    


  68. PATEL A, Gupta VG
    Adjuvant Endocrine Therapy for Premenopausal Breast Cancer.
    N Engl J Med. 2018;379:1683-4.
    PubMed    


  69. LOVE RR
    Adjuvant Endocrine Therapy for Premenopausal Breast Cancer.
    N Engl J Med. 2018;379:1683.
    PubMed    


  70. NEWMAN LA
    Gene Expression-Guided Adjuvant Chemotherapy in Breast Cancer.
    N Engl J Med. 2018;379:1681-2.
    PubMed    


  71. MCCAW ZR, Wei LJ, Kim DH
    Gene Expression-Guided Adjuvant Chemotherapy in Breast Cancer.
    N Engl J Med. 2018;379:1681.
    PubMed    


  72. CHENG Y, Wu Y, Wu L
    Gene Expression-Guided Adjuvant Chemotherapy in Breast Cancer.
    N Engl J Med. 2018;379:1680-1.
    PubMed    



  73. Adjuvant Endocrine Therapy for Premenopausal Breast Cancer.
    N Engl J Med. 2018;379:1683-1685.
    PubMed    



  74. Gene Expression-Guided Adjuvant Chemotherapy in Breast Cancer.
    N Engl J Med. 2018;379:1680-1682.
    PubMed    


  75. SCHMID P, Adams S, Rugo HS, Schneeweiss A, et al
    Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer.
    N Engl J Med. 2018 Oct 20. doi: 10.1056/NEJMoa1809615.
    PubMed     Abstract available


  76. TURNER NC, Slamon DJ, Ro J, Bondarenko I, et al
    Overall Survival with Palbociclib and Fulvestrant in Advanced Breast Cancer.
    N Engl J Med. 2018 Oct 20. doi: 10.1056/NEJMoa1810527.
    PubMed     Abstract available



  77. Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations; Adjuvant Pertuzumab and Trastuzumab in Early HER2-Positive Breast Cancer.
    N Engl J Med. 2018;379:1585.
    PubMed    



  78. Breast Cancer in Men.
    N Engl J Med. 2018;379:1385-1386.
    PubMed    


  79. KANAKIS GA, Jorgensen N, Goulis DG
    Breast Cancer in Men.
    N Engl J Med. 2018;379:1385.
    PubMed    


    August 2018
  80. LITTON JK, Rugo HS, Ettl J, Hurvitz SA, et al
    Talazoparib in Patients with Advanced Breast Cancer and a Germline BRCA Mutation.
    N Engl J Med. 2018 Aug 15. doi: 10.1056/NEJMoa1802905.
    PubMed     Abstract available


    July 2018
  81. STEARNS V
    TAILORing Adjuvant Systemic Therapy for Breast Cancer.
    N Engl J Med. 2018;379:191-192.
    PubMed    


    June 2018
  82. GIORDANO SH
    Breast Cancer in Men.
    N Engl J Med. 2018;378:2311-2320.
    PubMed    


  83. MULASI I
    The Scarlet Virus.
    N Engl J Med. 2018;378:2157-2159.
    PubMed    


  84. FRANCIS PA, Pagani O, Fleming GF, Walley BA, et al
    Tailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer.
    N Engl J Med. 2018 Jun 4. doi: 10.1056/NEJMoa1803164.
    PubMed     Abstract available


  85. LIPPMAN ME
    Endocrine Adjuvant Therapy for Localized Breast Cancer.
    N Engl J Med. 2018 Jun 4. doi: 10.1056/NEJMe1806130.
    PubMed    


  86. SPARANO JA, Gray RJ, Makower DF, Pritchard KI, et al
    Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer.
    N Engl J Med. 2018 Jun 3. doi: 10.1056/NEJMoa1804710.
    PubMed     Abstract available


    May 2018
  87. ELMORE SNC
    p53 and Me.
    N Engl J Med. 2018;378:1962-1963.
    PubMed    


    March 2018
  88. NACHTIGALL L, Naftolin F, Keefe DL
    Contemporary Hormonal Contraception and the Risk of Breast Cancer.
    N Engl J Med. 2018;378:1265.
    PubMed    


  89. CRAMER DW, Braaten K
    Contemporary Hormonal Contraception and the Risk of Breast Cancer.
    N Engl J Med. 2018;378:1264-8.
    PubMed    


  90. ROBERTS K, Merkatz RB, Vieira CS
    Contemporary Hormonal Contraception and the Risk of Breast Cancer.
    N Engl J Med. 2018;378:1264.
    PubMed    


  91. WOOD S
    Contemporary Hormonal Contraception and the Risk of Breast Cancer.
    N Engl J Med. 2018;378:1264.
    PubMed    


  92. SCHWARZ EB, Foster DG, Grossman D
    Contemporary Hormonal Contraception and the Risk of Breast Cancer.
    N Engl J Med. 2018;378:1263-4.
    PubMed    



  93. Contemporary Hormonal Contraception and the Risk of Breast Cancer.
    N Engl J Med. 2018;378:1263-1266.
    PubMed    



  94. Breast-Cancer Recurrence after Stopping Endocrine Therapy.
    N Engl J Med. 2018;378:870-871.
    PubMed    


  95. ANDERSON GM
    Breast-Cancer Recurrence after Stopping Endocrine Therapy.
    N Engl J Med. 2018;378:870.
    PubMed    


    January 2018
  96. VAN DEN HEUVELEIBRINK MM, van der Kooi ALF, Wallace WHB
    Fertility Preservation in Women.
    N Engl J Med. 2018;378:399-400.
    PubMed    


  97. DONNEZ J, Dolmans MM
    Fertility Preservation in Women.
    N Engl J Med. 2018;378:400-401.
    PubMed    


    December 2017
  98. TURNER NC
    Signatures of DNA-Repair Deficiencies in Breast Cancer.
    N Engl J Med. 2017;377:2490-2492.
    PubMed    


  99. MORCH LS, Skovlund CW, Hannaford PC, Iversen L, et al
    Contemporary Hormonal Contraception and the Risk of Breast Cancer.
    N Engl J Med. 2017;377:2228-2239.
    PubMed     Abstract available


  100. DEMICHELE A, Yee D, Esserman L
    Mechanisms of Resistance to Neoadjuvant Chemotherapy in Breast Cancer.
    N Engl J Med. 2017;377:2287-2289.
    PubMed    


  101. HUNTER DJ
    Oral Contraceptives and the Small Increased Risk of Breast Cancer.
    N Engl J Med. 2017;377:2276-2277.
    PubMed    


    November 2017
  102. PAN H, Gray R, Braybrooke J, Davies C, et al
    20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years.
    N Engl J Med. 2017;377:1836-1846.
    PubMed     Abstract available


  103. NAROD S, Booth CM, Foulkes WD
    Olaparib for Metastatic Germline BRCA-Mutated Breast Cancer.
    N Engl J Med. 2017;377:1792.
    PubMed    


  104. OIDE T, Mitsuishi T
    Pigmented Macule - A Skin Manifestation of Invasive Breast Cancer.
    N Engl J Med. 2017;377:1777.
    PubMed    



  105. Olaparib for Metastatic Germline BRCA-Mutated Breast Cancer.
    N Engl J Med. 2017;377:1792-3.
    PubMed    


  106. GREENE AK, Voss SD, Maclellan RA
    Liposuction for Swelling in Patients with Lymphedema.
    N Engl J Med. 2017;377:1788-1789.
    PubMed    


    October 2017
  107. LEMERY S, Keegan P, Pazdur R
    First FDA Approval Agnostic of Cancer Site - When a Biomarker Defines the Indication.
    N Engl J Med. 2017;377:1409-1412.
    PubMed    


    September 2017
  108. RAMASWAMI R, Morrow M, Jagsi R
    Contralateral Prophylactic Mastectomy.
    N Engl J Med. 2017;377:1288-1291.
    PubMed    


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