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COVID Reference, 5th edition, 486 pages

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Articles published in Proc Natl Acad Sci U S A

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    November 2020
  1. BARONE M, Muller M, Chiha S, Ren J, et al
    Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
    Proc Natl Acad Sci U S A. 2020 Nov 12. pii: 2007213117.
    PubMed     Abstract available


    October 2020
  2. YANG PB, Hou PP, Liu FY, Hong WB, et al
    Blocking PPARgamma interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression.
    Proc Natl Acad Sci U S A. 2020 Oct 21. pii: 2002997117.
    PubMed     Abstract available


    September 2020
  3. CHEN IX, Newcomer K, Pauken KE, Juneja VR, et al
    A bilateral tumor model identifies transcriptional programs associated with patient response to immune checkpoint blockade.
    Proc Natl Acad Sci U S A. 2020;117:23684-23694.
    PubMed     Abstract available


    August 2020
  4. KHATIB A, Solaimuthu B, Ben Yosef M, Abu Rmaileh A, et al
    The glutathione peroxidase 8 (GPX8)/IL-6/STAT3 axis is essential in maintaining an aggressive breast cancer phenotype.
    Proc Natl Acad Sci U S A. 2020 Aug 18. pii: 2010275117.
    PubMed     Abstract available


    July 2020
  5. MCLAUGHLIN LJ, Stojanovic L, Kogan AA, Rutherford JL, et al
    Pharmacologic induction of innate immune signaling directly drives homologous recombination deficiency.
    Proc Natl Acad Sci U S A. 2020;117:17785-17795.
    PubMed     Abstract available


  6. CALLMANN CE, Cole LE, Kusmierz CD, Huang Z, et al
    Tumor cell lysate-loaded immunostimulatory spherical nucleic acids as therapeutics for triple-negative breast cancer.
    Proc Natl Acad Sci U S A. 2020 Jul 15. pii: 2005794117.
    PubMed     Abstract available


  7. ZERVANTONAKIS IK, Poskus MD, Scott AL, Selfors LM, et al
    Fibroblast-tumor cell signaling limits HER2 kinase therapy response via activation of MTOR and antiapoptotic pathways.
    Proc Natl Acad Sci U S A. 2020;117:16500-16508.
    PubMed     Abstract available


    June 2020
  8. GRAVES JD, Lee YJ, Liu K, Li G, et al
    E2F1 sumoylation as a protective cellular mechanism in oxidative stress response.
    Proc Natl Acad Sci U S A. 2020;117:14958-14969.
    PubMed     Abstract available


  9. ZHU N, Zhang J, Du Y, Qin X, et al
    Loss of ZIP facilitates JAK2-STAT3 activation in tamoxifen-resistant breast cancer.
    Proc Natl Acad Sci U S A. 2020 Jun 12. pii: 1910278117.
    PubMed     Abstract available


    April 2020
  10. LEE S, Hu Y, Loo SK, Tan Y, et al
    Landscape analysis of adjacent gene rearrangements reveals BCL2L14-ETV6 gene fusions in more aggressive triple-negative breast cancer.
    Proc Natl Acad Sci U S A. 2020 Apr 22. pii: 1921333117.
    PubMed     Abstract available


  11. CARVAJAL-GARCIA J, Cho JE, Carvajal-Garcia P, Feng W, et al
    Mechanistic basis for microhomology identification and genome scarring by polymerase theta.
    Proc Natl Acad Sci U S A. 2020;117:8476-8485.
    PubMed     Abstract available


  12. LEUNG KK, Wilson GM, Kirkemo LL, Riley NM, et al
    Broad and thematic remodeling of the surfaceome and glycoproteome on isogenic cells transformed with driving proliferative oncogenes.
    Proc Natl Acad Sci U S A. 2020;117:7764-7775.
    PubMed     Abstract available


  13. KUMAR S, Singh SK, Viswakarma N, Sondarva G, et al
    Mixed lineage kinase 3 inhibition induces T cell activation and cytotoxicity.
    Proc Natl Acad Sci U S A. 2020;117:7961-7970.
    PubMed     Abstract available


    March 2020
  14. YI Y, Chen D, Ao J, Zhang W, et al
    Transcriptional suppression of AMPKalpha1 promotes breast cancer metastasis upon oncogene activation.
    Proc Natl Acad Sci U S A. 2020 Mar 19. pii: 1914786117.
    PubMed     Abstract available


  15. NA TY, Schecterson L, Mendonsa AM, Gumbiner BM, et al
    The functional activity of E-cadherin controls tumor cell metastasis at multiple steps.
    Proc Natl Acad Sci U S A. 2020;117:5931-5937.
    PubMed     Abstract available


  16. PHILLIPS JW, Pan Y, Tsai BL, Xie Z, et al
    Pathway-guided analysis identifies Myc-dependent alternative pre-mRNA splicing in aggressive prostate cancers.
    Proc Natl Acad Sci U S A. 2020;117:5269-5279.
    PubMed     Abstract available


  17. KESAVAN R, Fromel T, Zukunft S, Laban H, et al
    Cyp2c44 regulates prostaglandin synthesis, lymphangiogenesis, and metastasis in a mouse model of breast cancer.
    Proc Natl Acad Sci U S A. 2020 Mar 2. pii: 1921381117.
    PubMed     Abstract available


    February 2020
  18. SCHNELL M, Mittal S, Falahkheirkhah K, Mittal A, et al
    All-digital histopathology by infrared-optical hybrid microscopy.
    Proc Natl Acad Sci U S A. 2020;117:3388-3396.
    PubMed     Abstract available


  19. BRANDT AC, McNally L, Lorimer EL, Unger B, et al
    Splice switching an oncogenic ratio of SmgGDS isoforms as a strategy to diminish malignancy.
    Proc Natl Acad Sci U S A. 2020;117:3627-3636.
    PubMed     Abstract available


  20. XIONG G, Chen J, Zhang G, Wang S, et al
    Hsp47 promotes cancer metastasis by enhancing collagen-dependent cancer cell-platelet interaction.
    Proc Natl Acad Sci U S A. 2020;117:3748-3758.
    PubMed     Abstract available


  21. COSTALES MG, Aikawa H, Li Y, Childs-Disney JL, et al
    Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer.
    Proc Natl Acad Sci U S A. 2020;117:2406-2411.
    PubMed     Abstract available


    January 2020
  22. PUGACHEVA EM, Kubo N, Loukinov D, Tajmul M, et al
    CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention.
    Proc Natl Acad Sci U S A. 2020;117:2020-2031.
    PubMed     Abstract available


  23. GALLAGHER FA, Woitek R, McLean MA, Gill AB, et al
    Imaging breast cancer using hyperpolarized carbon-13 MRI.
    Proc Natl Acad Sci U S A. 2020 Jan 21. pii: 1913841117.
    PubMed     Abstract available


  24. BLOCKHUYS S, Zhang X, Wittung-Stafshede P
    Single-cell tracking demonstrates copper chaperone Atox1 to be required for breast cancer cell migration.
    Proc Natl Acad Sci U S A. 2020 Jan 13. pii: 1910722117.
    PubMed     Abstract available


  25. WINKLER I, Bitter C, Winkler S, Weichenhan D, et al
    Identification of Ppargamma-modulated miRNA hubs that target the fibrotic tumor microenvironment.
    Proc Natl Acad Sci U S A. 2020;117:454-463.
    PubMed     Abstract available


  26. LIN CW, Xie J, Zhang D, Han KH, et al
    Immunity against cancer cells may promote their proliferation and metastasis.
    Proc Natl Acad Sci U S A. 2020;117:426-431.
    PubMed     Abstract available


    December 2019
  27. GREENE KS, Lukey MJ, Wang X, Blank B, et al
    SIRT5 stabilizes mitochondrial glutaminase and supports breast cancer tumorigenesis.
    Proc Natl Acad Sci U S A. 2019 Dec 16. pii: 1911954116.
    PubMed     Abstract available


  28. FU X, Pereira R, De Angelis C, Veeraraghavan J, et al
    FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer.
    Proc Natl Acad Sci U S A. 2019 Dec 11. pii: 1911584116.
    PubMed     Abstract available


  29. BANERJEE S, Wei T, Wang J, Lee JJ, et al
    Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression.
    Proc Natl Acad Sci U S A. 2019;116:24881-24891.
    PubMed     Abstract available


    November 2019
  30. HJELMELAND AB, Patel RP
    SOD2 acetylation and deacetylation: Another tale of Jekyll and Hyde in cancer.
    Proc Natl Acad Sci U S A. 2019;116:23376-23378.
    PubMed    


  31. YOU S, Barkalifa R, Chaney EJ, Tu H, et al
    Label-free visualization and characterization of extracellular vesicles in breast cancer.
    Proc Natl Acad Sci U S A. 2019 Nov 15. pii: 1909243116.
    PubMed     Abstract available


  32. RODRIGUES-FERREIRA S, Nehlig A, Moindjie H, Monchecourt C, et al
    Improving breast cancer sensitivity to paclitaxel by increasing aneuploidy.
    Proc Natl Acad Sci U S A. 2019 Nov 4. pii: 1910824116.
    PubMed     Abstract available


    October 2019
  33. KREUZALER P, Clarke MA, Brown EJ, Wilson CH, et al
    Heterogeneity of Myc expression in breast cancer exposes pharmacological vulnerabilities revealed through executable mechanistic modeling.
    Proc Natl Acad Sci U S A. 2019 Oct 14. pii: 1903485116.
    PubMed     Abstract available


  34. HAGERLING C, Gonzalez H, Salari K, Wang CY, et al
    Immune effector monocyte-neutrophil cooperation induced by the primary tumor prevents metastatic progression of breast cancer.
    Proc Natl Acad Sci U S A. 2019 Oct 7. pii: 1907660116.
    PubMed     Abstract available


  35. HE C, Danes JM, Hart PC, Zhu Y, et al
    SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer.
    Proc Natl Acad Sci U S A. 2019 Oct 7. pii: 1902308116.
    PubMed     Abstract available


    May 2019
  36. MOROTTI M, Bridges E, Valli A, Choudhry H, et al
    Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine resistance in breast cancer.
    Proc Natl Acad Sci U S A. 2019 May 31. pii: 1818521116.
    PubMed     Abstract available



  37. Correction for Kroger et al., Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells.
    Proc Natl Acad Sci U S A. 2019 May 28. pii: 1907473116.
    PubMed    


  38. BAI J, Wu K, Cao MH, Yang Y, et al
    SCF(FBXO22) targets HDM2 for degradation and modulates breast cancer cell invasion and metastasis.
    Proc Natl Acad Sci U S A. 2019 May 28. pii: 1820990116.
    PubMed     Abstract available


    April 2019
  39. VERMA S, Yeddula N, Soda Y, Zhu Q, et al
    BRCA1/BARD1-dependent ubiquitination of NF2 regulates Hippo-YAP1 signaling.
    Proc Natl Acad Sci U S A. 2019;116:7363-7370.
    PubMed     Abstract available


  40. SHANBHAG V, Jasmer-McDonald K, Zhu S, Martin AL, et al
    ATP7A delivers copper to the lysyl oxidase family of enzymes and promotes tumorigenesis and metastasis.
    Proc Natl Acad Sci U S A. 2019;116:6836-6841.
    PubMed     Abstract available


    March 2019
  41. ZHANG J, Goliwas KF, Wang W, Taufalele PV, et al
    Energetic regulation of coordinated leader-follower dynamics during collective invasion of breast cancer cells.
    Proc Natl Acad Sci U S A. 2019 Mar 28. pii: 1809964116.
    PubMed     Abstract available


  42. CROW M, Lim N, Ballouz S, Pavlidis P, et al
    Predictability of human differential gene expression.
    Proc Natl Acad Sci U S A. 2019;116:6491-6500.
    PubMed     Abstract available


  43. KROGER C, Afeyan A, Mraz J, Eaton EN, et al
    Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells.
    Proc Natl Acad Sci U S A. 2019 Mar 25. pii: 1812876116.
    PubMed     Abstract available



  44. Correction for Blasco-Benito et al., Therapeutic targeting of HER2-CB2R heteromers in HER2-positive breast cancer.
    Proc Natl Acad Sci U S A. 2019 Mar 18. pii: 1903209116.
    PubMed    


    February 2019
  45. CHUANG PK, Hsiao M, Hsu TL, Chang CF, et al
    Signaling pathway of globo-series glycosphingolipids and beta1,3-galactosyltransferase V (beta3GalT5) in breast cancer.
    Proc Natl Acad Sci U S A. 2019;116:3518-3523.
    PubMed     Abstract available


  46. ONDECK MG, Kumar A, Placone JK, Plunkett CM, et al
    Dynamically stiffened matrix promotes malignant transformation of mammary epithelial cells via collective mechanical signaling.
    Proc Natl Acad Sci U S A. 2019;116:3502-3507.
    PubMed     Abstract available


  47. JIA D, Lu M, Jung KH, Park JH, et al
    Elucidating cancer metabolic plasticity by coupling gene regulation with metabolic pathways.
    Proc Natl Acad Sci U S A. 2019;116:3909-3918.
    PubMed     Abstract available


  48. SLEDGE GW
    Targeting CXCR4-induced desmoplasia to improve checkpoint inhibition in breast cancer.
    Proc Natl Acad Sci U S A. 2019 Feb 22. pii: 1900368116.
    PubMed    


  49. VOUTOURI C, Kirkpatrick ND, Chung E, Mpekris F, et al
    Experimental and computational analyses reveal dynamics of tumor vessel cooption and optimal treatment strategies.
    Proc Natl Acad Sci U S A. 2019;116:2662-2671.
    PubMed     Abstract available


  50. LI X, Gruosso T, Zuo D, Omeroglu A, et al
    Infiltration of CD8(+) T cells into tumor cell clusters in triple-negative breast cancer.
    Proc Natl Acad Sci U S A. 2019 Feb 7. pii: 1817652116.
    PubMed     Abstract available


  51. BLASCO-BENITO S, Moreno E, Seijo-Vila M, Tundidor I, et al
    Therapeutic targeting of HER2-CB2R heteromers in HER2-positive breast cancer.
    Proc Natl Acad Sci U S A. 2019 Feb 7. pii: 1815034116.
    PubMed     Abstract available


  52. KUBLI SP, Bassi C, Roux C, Wakeham A, et al
    AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer.
    Proc Natl Acad Sci U S A. 2019 Feb 7. pii: 1815126116.
    PubMed     Abstract available


    January 2019
  53. CHEN IX, Chauhan VP, Posada J, Ng MR, et al
    Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer.
    Proc Natl Acad Sci U S A. 2019 Jan 30. pii: 1815515116.
    PubMed     Abstract available


  54. KOBOLD S
    Innate and adaptive immunity combined for cancer treatment.
    Proc Natl Acad Sci U S A. 2019;116:1087-1088.
    PubMed    


  55. ZHANG S, Zhang H, Ghia EM, Huang J, et al
    Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody.
    Proc Natl Acad Sci U S A. 2019 Jan 8. pii: 1816262116.
    PubMed     Abstract available


    December 2018
  56. TOMINAGA K, Minato H, Murayama T, Sasahara A, et al
    Semaphorin signaling via MICAL3 induces symmetric cell division to expand breast cancer stem-like cells.
    Proc Natl Acad Sci U S A. 2018 Dec 26. pii: 1806851116.
    PubMed     Abstract available


  57. BOCCI F, Gearhart-Serna L, Boareto M, Ribeiro M, et al
    Toward understanding cancer stem cell heterogeneity in the tumor microenvironment.
    Proc Natl Acad Sci U S A. 2018 Dec 26. pii: 1815345116.
    PubMed     Abstract available


  58. KAPLANOV I, Carmi Y, Kornetsky R, Shemesh A, et al
    Blocking IL-1beta reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation.
    Proc Natl Acad Sci U S A. 2018 Dec 13. pii: 1812266115.
    PubMed     Abstract available


  59. TOKUYAMA M, Kong Y, Song E, Jayewickreme T, et al
    ERVmap analysis reveals genome-wide transcription of human endogenous retroviruses.
    Proc Natl Acad Sci U S A. 2018;115:12565-12572.
    PubMed     Abstract available


  60. LIU C, Sun L, Yang J, Liu T, et al
    FSIP1 regulates autophagy in breast cancer.
    Proc Natl Acad Sci U S A. 2018 Dec 3. pii: 1809681115.
    PubMed     Abstract available


    November 2018
  61. MATSUNUMA R, Chan DW, Kim BJ, Singh P, et al
    DPYSL3 modulates mitosis, migration, and epithelial-to-mesenchymal transition in claudin-low breast cancer.
    Proc Natl Acad Sci U S A. 2018 Nov 29. pii: 1810598115.
    PubMed     Abstract available


    October 2018
  62. SUN XX, Chen Y, Su Y, Wang X, et al
    SUMO protease SENP1 deSUMOylates and stabilizes c-Myc.
    Proc Natl Acad Sci U S A. 2018;115:10983-10988.
    PubMed     Abstract available


  63. LIANG W, Li Q, Ferrara N
    Metastatic growth instructed by neutrophil-derived transferrin.
    Proc Natl Acad Sci U S A. 2018;115:11060-11065.
    PubMed     Abstract available


    September 2018
  64. REESE JM, Bruinsma ES, Nelson AW, Chernukhin I, et al
    ERbeta-mediated induction of cystatins results in suppression of TGFbeta signaling and inhibition of triple-negative breast cancer metastasis.
    Proc Natl Acad Sci U S A. 2018 Sep 26. pii: 1807751115.
    PubMed     Abstract available


  65. GURYEV EL, Volodina NO, Shilyagina NY, Gudkov SV, et al
    Radioactive ((90)Y) upconversion nanoparticles conjugated with recombinant targeted toxin for synergistic nanotheranostics of cancer.
    Proc Natl Acad Sci U S A. 2018;115:9690-9695.
    PubMed     Abstract available


  66. LAN J, Lu H, Samanta D, Salman S, et al
    Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment.
    Proc Natl Acad Sci U S A. 2018 Sep 21. pii: 1809695115.
    PubMed     Abstract available


  67. CHU B, He A, Tian Y, He W, et al
    Photoaffinity-engineered protein scaffold for systematically exploring native phosphotyrosine signaling complexes in tumor samples.
    Proc Natl Acad Sci U S A. 2018;115:E8863-E8872.
    PubMed     Abstract available


    August 2018
  68. ARVANITIS CD, Askoxylakis V, Guo Y, Datta M, et al
    Mechanisms of enhanced drug delivery in brain metastases with focused ultrasound-induced blood-tumor barrier disruption.
    Proc Natl Acad Sci U S A. 2018 Aug 27. pii: 1807105115.
    PubMed     Abstract available


  69. GRITHER WR, Longmore GD
    Inhibition of tumor-microenvironment interaction and tumor invasion by small-molecule allosteric inhibitor of DDR2 extracellular domain.
    Proc Natl Acad Sci U S A. 2018;115:E7786-E7794.
    PubMed     Abstract available


  70. DATTA S, Misra SK, Saha ML, Lahiri N, et al
    Orthogonal self-assembly of an organoplatinum(II) metallacycle and cucurbit[8]uril that delivers curcumin to cancer cells.
    Proc Natl Acad Sci U S A. 2018;115:8087-8092.
    PubMed     Abstract available


  71. FOULDS CE
    Disrupting a negative feedback loop drives endocrine therapy-resistant breast cancer.
    Proc Natl Acad Sci U S A. 2018 Aug 6. pii: 1811263115.
    PubMed    


    July 2018
  72. REN C, Zhang G, Han F, Fu S, et al
    Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth.
    Proc Natl Acad Sci U S A. 2018;115:7949-7954.
    PubMed     Abstract available


  73. WANG B, Li D, Kovalchuk I, Apel IJ, et al
    miR-34a directly targets tRNAi(Met) precursors and affects cellular proliferation, cell cycle, and apoptosis.
    Proc Natl Acad Sci U S A. 2018;115:7392-7397.
    PubMed     Abstract available


  74. XIAO T, Li W, Wang X, Xu H, et al
    Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.
    Proc Natl Acad Sci U S A. 2018 Jul 9. pii: 1722617115.
    PubMed     Abstract available


  75. LEE JJ, van de Ven RAH, Zaganjor E, Ng MR, et al
    Inhibition of epithelial cell migration and Src/FAK signaling by SIRT3.
    Proc Natl Acad Sci U S A. 2018;115:7057-7062.
    PubMed     Abstract available


    June 2018
  76. MITTAL S, Yeh K, Leslie LS, Kenkel S, et al
    Simultaneous cancer and tumor microenvironment subtyping using confocal infrared microscopy for all-digital molecular histopathology.
    Proc Natl Acad Sci U S A. 2018;115:E5651-E5660.
    PubMed     Abstract available


  77. SUN X, Wang X, Tang Z, Grivainis M, et al
    Transcription factor profiling reveals molecular choreography and key regulators of human retrotransposon expression.
    Proc Natl Acad Sci U S A. 2018;115:E5526-E5535.
    PubMed     Abstract available


  78. DE SEMIR D, Bezrookove V, Nosrati M, Dar AA, et al
    PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer.
    Proc Natl Acad Sci U S A. 2018 Jun 4. pii: 1804779115.
    PubMed     Abstract available


    May 2018
  79. ROY B, Venkatachalapathy S, Ratna P, Wang Y, et al
    Laterally confined growth of cells induces nuclear reprogramming in the absence of exogenous biochemical factors.
    Proc Natl Acad Sci U S A. 2018;115:E4741-E4750.
    PubMed     Abstract available


  80. SEO A, Steinberg-Shemer O, Unal S, Casadei S, et al
    Mechanism for survival of homozygous nonsense mutations in the tumor suppressor gene BRCA1.
    Proc Natl Acad Sci U S A. 2018;115:5241-5246.
    PubMed     Abstract available


  81. LAI X, Stiff A, Duggan M, Wesolowski R, et al
    Modeling combination therapy for breast cancer with BET and immune checkpoint inhibitors.
    Proc Natl Acad Sci U S A. 2018 May 7. pii: 1721559115.
    PubMed     Abstract available


    April 2018
  82. NAIR P, Vilcek J
    Profile of Alexander Y. Rudensky, winner of the 2018 Vilcek Prize in Biomedical Science.
    Proc Natl Acad Sci U S A. 2018;115:4301-4304.
    PubMed    


  83. VEGA-RUBIN-DE-CELIS S, Zou Z, Fernandez AF, Ci B, et al
    Increased autophagy blocks HER2-mediated breast tumorigenesis.
    Proc Natl Acad Sci U S A. 2018;115:4176-4181.
    PubMed     Abstract available


  84. ZHAO L, Huang S, Mei S, Yang Z, et al
    Pharmacological activation of estrogen receptor beta augments innate immunity to suppress cancer metastasis.
    Proc Natl Acad Sci U S A. 2018;115:E3673-E3681.
    PubMed     Abstract available


    March 2018
  85. KE H, Zhao L, Zhang H, Feng X, et al
    Loss of TDP43 inhibits progression of triple-negative breast cancer in coordination with SRSF3.
    Proc Natl Acad Sci U S A. 2018 Mar 26. pii: 1714573115.
    PubMed     Abstract available


  86. FLOROS KV, Lochmann TL, Hu B, Monterrubio C, et al
    Coamplification of miR-4728 protects HER2-amplified breast cancers from targeted therapy.
    Proc Natl Acad Sci U S A. 2018;115:E2594-E2603.
    PubMed     Abstract available


    February 2018
  87. HASHIMOTO K, Ochi H, Sunamura S, Kosaka N, et al
    Cancer-secreted hsa-miR-940 induces an osteoblastic phenotype in the bone metastatic microenvironment via targeting ARHGAP1 and FAM134A.
    Proc Natl Acad Sci U S A. 2018;115:2204-2209.
    PubMed     Abstract available


    January 2018
  88. THU KL, Silvester J, Elliott MJ, Ba-Alawi W, et al
    Disruption of the anaphase-promoting complex confers resistance to TTK inhibitors in triple-negative breast cancer.
    Proc Natl Acad Sci U S A. 2018 Jan 29. pii: 1719577115.
    PubMed     Abstract available


  89. SAMANTA D, Park Y, Ni X, Li H, et al
    Chemotherapy induces enrichment of CD47(+)/CD73(+)/PDL1(+) immune evasive triple-negative breast cancer cells.
    Proc Natl Acad Sci U S A. 2018 Jan 24. pii: 1718197115.
    PubMed     Abstract available


  90. DEVIGNES CS, Aslan Y, Brenot A, Devillers A, et al
    HIF signaling in osteoblast-lineage cells promotes systemic breast cancer growth and metastasis in mice.
    Proc Natl Acad Sci U S A. 2018 Jan 16. pii: 1718009115.
    PubMed     Abstract available


    December 2017
  91. DOHERTY MR, Cheon H, Junk DJ, Vinayak S, et al
    Interferon-beta represses cancer stem cell properties in triple-negative breast cancer.
    Proc Natl Acad Sci U S A. 2017 Dec 11. pii: 1713728114.
    PubMed     Abstract available


    November 2017
  92. BEAUSANG JF, Wheeler AJ, Chan NH, Hanft VR, et al
    T cell receptor sequencing of early-stage breast cancer tumors identifies altered clonal structure of the T cell repertoire.
    Proc Natl Acad Sci U S A. 2017 Nov 14. pii: 201713863.
    PubMed     Abstract available



  93. Correction for Sansone et al., Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer.
    Proc Natl Acad Sci U S A. 2017 Nov 13. pii: 201718630.
    PubMed    


    October 2017
  94. BASUDHAR D, Glynn SA, Greer M, Somasundaram V, et al
    Coexpression of NOS2 and COX2 accelerates tumor growth and reduces survival in estrogen receptor-negative breast cancer.
    Proc Natl Acad Sci U S A. 2017 Oct 27. pii: 201709119.
    PubMed     Abstract available


  95. SANSONE P, Savini C, Kurelac I, Chang Q, et al
    Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer.
    Proc Natl Acad Sci U S A. 2017;114:E9066-E9075.
    PubMed     Abstract available


    September 2017
  96. HE F, Chiou AE, Loh HC, Lynch M, et al
    Multiscale characterization of the mineral phase at skeletal sites of breast cancer metastasis.
    Proc Natl Acad Sci U S A. 2017 Sep 18. pii: 201708161.
    PubMed     Abstract available


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