Retrieve available abstracts of 39 articles: HTML format
Single Articles
July 2025
HORWITZ E, Dubash TD, Szabolcs A, Wittner BS, et al CDKN1B (p27/kip1) enhances drug-tolerant persister CTCs by restricting polyploidy
following mitotic inhibitors.
Proc Natl Acad Sci U S A. 2025;122:e2507203122. PubMedAbstract available
SUN R, Jiang P, Wang Z, Yan B, et al DNA2 protein destruction dictates DNA hyperexcision, cGAS-STING activation, and
innate immune response in CDK12-deregulated cancers.
Proc Natl Acad Sci U S A. 2025;122:e2413732122. PubMedAbstract available
ZOU Y, Wang Z, Jiang Q, Kong X, et al UFMylation: A supervisor of the HIF1alpha pathway and a potential therapeutic target
for anti-PD-1 combination therapy in hypoxic tumors.
Proc Natl Acad Sci U S A. 2025;122:e2500562122. PubMedAbstract available
GUO J, Li K, Ming Y, Pan Y, et al A circular RNA overcomes acquired resistance to BET inhibitors by antagonizing
IGF2BP2-mediated c-MYC translation in TNBC.
Proc Natl Acad Sci U S A. 2025;122:e2504320122. PubMedAbstract available
LIM J, Jung HD, Park SY, Jeon M, et al Genome-scale knockout simulation and clustering analysis of drug-resistant breast
cancer cells reveal drug sensitization targets.
Proc Natl Acad Sci U S A. 2025;122:e2425384122. PubMedAbstract available
June 2025
ZENG W, Guo H, Liu Q, Wong WH, et al Improving polygenic prediction from whole-genome sequencing data by leveraging
predicted epigenomic features.
Proc Natl Acad Sci U S A. 2025;122:e2419202122. PubMedAbstract available
OZAKI MK, Zhang Y, Bartlett AQ, de Wilde E, et al Reproductive state controls transcription in the murine liver, with implications
for breast cancer liver metastasis.
Proc Natl Acad Sci U S A. 2025;122:e2420174122. PubMedAbstract available
DING Q, Liu J, Wang Y, Kim J, et al Dual-laser "808 and 1,064 nm" strategy that circumvents the Achilles' heel of
photothermal therapy.
Proc Natl Acad Sci U S A. 2025;122:e2503574122. PubMedAbstract available
May 2025
FERRERO G, Cardamone MD, Luca F, Bourk E, et al Nonproteolytic ubiquitination regulates chromatin occupancy by the
NCoR/SMRT/HDAC3 corepressor complex in MCF-7 breast cancer cells.
Proc Natl Acad Sci U S A. 2025;122:e2502805122. PubMedAbstract available
April 2025
CHEN YF, Zhang QH, Zhang ZW, Zhou YJ, et al SNX10 deficiency impairs sensitivity to anti-HER2 antibody-drug conjugates via
altering HER2 trafficking in HER2-positive breast cancer.
Proc Natl Acad Sci U S A. 2025;122:e2417586122. PubMedAbstract available
ZHAO X, Zhao Y, Li Z, Liu H, et al Proximity-activated DNA scanning encoded sequencing for massive access to
membrane proteins nanoscale organization.
Proc Natl Acad Sci U S A. 2025;122:e2425000122. PubMedAbstract available
March 2025
Correction for Qin et al., A signaling molecule from intratumor bacteria promotes
trastuzumab resistance in breast cancer cells.
Proc Natl Acad Sci U S A. 2025;122:e2502214122. PubMed
STAROSTECKA M, Jeong H, Hasenfeld P, Benito-Garagorri E, et al Structural variant and nucleosome occupancy dynamics postchemotherapy in a HER2+
breast cancer organoid model.
Proc Natl Acad Sci U S A. 2025;122:e2415475122. PubMedAbstract available
February 2025
YI J, Du J, Chen X, Nie RC, et al A circRNA-mRNA pairing mechanism regulates tumor growth and endocrine therapy
resistance in ER-positive breast cancer.
Proc Natl Acad Sci U S A. 2025;122:e2420383122. PubMedAbstract available
LEI L, Song Y, Yang L, Wang Y, et al Triethylamine-mediated protonation-deprotonation unlocks dual-drug self assembly
to suppress breast cancer progression and metastasis.
Proc Natl Acad Sci U S A. 2025;122:e2416796122. PubMedAbstract available
January 2025
QIN G, Shao X, Liu X, Xu J, et al A signaling molecule from intratumor bacteria promotes trastuzumab resistance in
breast cancer cells.
Proc Natl Acad Sci U S A. 2025;122:e2421710122. PubMedAbstract available
ZHENG M, Wang S, Tang K, Kong R, et al The CYLD-PARP1 feedback loop regulates DNA damage repair and chemosensitivity in
breast cancer cells.
Proc Natl Acad Sci U S A. 2025;122:e2413890121. PubMedAbstract available
December 2024
GONZALEZ-FERNANDEZ M, Perry C, Gerhards NM, Francica P, et al Docetaxel response in BRCA1,p53-deficient mammary tumor cells is affected by
Huntingtin and BAP1.
Proc Natl Acad Sci U S A. 2024;121:e2402849121. PubMedAbstract available
SINHA A, Saini KK, Chandramouli A, Tripathi K, et al ACSL4-mediated H3K9 and H3K27 hyperacetylation upregulates SNAIL to drive TNBC
metastasis.
Proc Natl Acad Sci U S A. 2024;121:e2408049121. PubMedAbstract available
MATSUZAKI T, Fujii M, Noro H, Togo S, et al Simultaneous visualization of membrane fluidity and morphology defines adhesion
signatures of cancer cells.
Proc Natl Acad Sci U S A. 2024;121:e2412914121. PubMedAbstract available
November 2024
DING X, Liang J, Sharko AC, Hilimire TA, et al Mediator kinase inhibitors suppress triple-negative breast cancer growth and
extend tumor suppression by mTOR and AKT inhibitors.
Proc Natl Acad Sci U S A. 2024;121:e2414501121. PubMedAbstract available
ARULRAJ T, Wang H, Deshpande A, Varadhan R, et al Virtual patient analysis identifies strategies to improve the performance of
predictive biomarkers for PD-1 blockade.
Proc Natl Acad Sci U S A. 2024;121:e2410911121. PubMedAbstract available
October 2024
LI C, Kaur A, Pavlidaki A, Spenle C, et al Targeting the MAtrix REgulating MOtif abolishes several hallmarks of cancer,
triggering antitumor immunity.
Proc Natl Acad Sci U S A. 2024;121:e2404485121. PubMedAbstract available
BALDASSARRI I, Tavakol DN, Graney PL, Chramiec AG, et al An engineered model of metastatic colonization of human bone marrow reveals
breast cancer cell remodeling of the hematopoietic niche.
Proc Natl Acad Sci U S A. 2024;121:e2405257121. PubMedAbstract available
Correction for Zhang et al., HIF-1 regulates CD47 expression in breast cancer
cells to promote evasion of phagocytosis and maintenance of cancer stem cells.
Proc Natl Acad Sci U S A. 2024;121:e2418194121. PubMed
ASEMOTA S, Effah W, Holt J, Johnson D, et al A molecular switch from tumor suppressor to oncogene in ER+ve breast cancer: Role
of androgen receptor, JAK-STAT, and lineage plasticity.
Proc Natl Acad Sci U S A. 2024;121:e2406837121. PubMedAbstract available
September 2024
FENG X, Yang C, Huang Y, Su D, et al In vivo CRISPR screens identify Mga as an immunotherapy target in triple-negative
breast cancer.
Proc Natl Acad Sci U S A. 2024;121:e2406325121. PubMedAbstract available
August 2024
CHIANG HC, Qi L, Mitra P, Huang Y, et al R-loop functions in Brca1-associated mammary tumorigenesis.
Proc Natl Acad Sci U S A. 2024;121:e2403600121. PubMedAbstract available
July 2024
SHAH OS, Nasrazadani A, Foldi J, Atkinson JM, et al Spatial molecular profiling of mixed invasive ductal and lobular breast cancers
reveals heterogeneity in intrinsic molecular subtypes, oncogenic signatures, and
mutations.
Proc Natl Acad Sci U S A. 2024;121:e2322068121. PubMedAbstract available
ZIN I, China A, Khan K, Nag JK, et al AKT-dependent nuclear localization of EPRS1 activates PARP1 in breast cancer
cells.
Proc Natl Acad Sci U S A. 2024;121:e2303642121. PubMedAbstract available
ZHOU Q, Yu H, Chen Y, Ren J, et al The CRL3(KCTD10) ubiquitin ligase-USP18 axis coordinately regulates cystine
uptake and ferroptosis by modulating SLC7A11.
Proc Natl Acad Sci U S A. 2024;121:e2320655121. PubMedAbstract available
June 2024
RUAN ML, Ni WX, Chu JCH, Lam TL, et al Iridium(III) carbene complexes as potent girdin inhibitors against metastatic
cancers.
Proc Natl Acad Sci U S A. 2024;121:e2316615121. PubMedAbstract available
May 2024
CHEN J, Liu X, Zou Y, Gong J, et al A high-fat diet promotes cancer progression by inducing gut microbiota-mediated
leucine production and PMN-MDSC differentiation.
Proc Natl Acad Sci U S A. 2024;121:e2306776121. PubMedAbstract available
ASHOKAN A, Sarkar S, Kamran MZ, Surnar B, et al Simultaneous targeting of peripheral and brain tumors with a therapeutic
nanoparticle to disrupt metabolic adaptability at both sites.
Proc Natl Acad Sci U S A. 2024;121:e2318119121. PubMedAbstract available
GOYETTE MA, Stevens LE, DePinho CR, Seehawer M, et al Cancer-stromal cell interactions in breast cancer brain metastases induce
glycocalyx-mediated resistance to HER2-targeting therapies.
Proc Natl Acad Sci U S A. 2024;121:e2322688121. PubMedAbstract available
April 2024
MONDAL DK, Xie C, Pascal GJ, Buraschi S, et al Decorin suppresses tumor lymphangiogenesis: A mechanism to curtail cancer
progression.
Proc Natl Acad Sci U S A. 2024;121:e2317760121. PubMedAbstract available
March 2024
WANG D, Tang M, Zhang P, Yang K, et al Activation of ERbeta hijacks the splicing machinery to trigger R-loop formation in
triple-negative breast cancer.
Proc Natl Acad Sci U S A. 2024;121:e2306814121. PubMedAbstract available
TAYLOR-PHILLIPS S, Jenkinson D, Stinton C, Kunar MA, et al Fatigue and vigilance in medical experts detecting breast cancer.
Proc Natl Acad Sci U S A. 2024;121:e2309576121. PubMedAbstract available
LAMIA KA Telling time in tumor samples reveals diversity of clock disruption.
Proc Natl Acad Sci U S A. 2024;121:e2401496121. PubMed