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  Liver Cirrhosis

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Articles published in Gastroenterology

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    November 2021
  1. BHAGAT N, Rathi S, Singh V
    Early Transplantation for Alcohol-Related Cirrhosis: Risks, Resources, and Relapse.
    Gastroenterology. 2021 Nov 5. pii: S0016-5085(21)03724.
    PubMed    


    October 2021
  2. LEE TH, Roper J, King L
    MIRROR MIRROR ON THE WALL, WHO IS THE FITTEST OF THEM ALL: A NOVEL PREDICTION MODEL FOR POSTOPERATIVE HEPATIC DECOMPENSATION IN PATIENTS WITH CIRRHOSIS.
    Gastroenterology. 2021 Oct 21. pii: S0016-5085(21)03662.
    PubMed     Abstract available


    September 2021
  3. INTAGLIATA NM, Davitkov P, Allen AM, Falck-Ytter YT, et al
    AGA Technical Review on Coagulation in Cirrhosis.
    Gastroenterology. 2021 Sep 24. pii: S0016-5085(21)03477.
    PubMed    


  4. O'SHEA RS, Davitkov P, Ko CW, Rajasekhar A, et al
    AGA Clinical Practice Guideline on the Management of Coagulation Disorders in Patients With Cirrhosis.
    Gastroenterology. 2021 Sep 24. pii: S0016-5085(21)03382.
    PubMed    


  5. BEKKI Y, Fenig Y
    Evaluation of Early Liver Transplantation for Alcohol-Related Cirrhosis.
    Gastroenterology. 2021 Sep 13. pii: S0016-5085(21)03491.
    PubMed    


    August 2021
  6. SU F
    COVID-19 and cirrhosis: a combination we must strive to prevent.
    Gastroenterology. 2021 Aug 25. pii: S0016-5085(21)03417.
    PubMed    


  7. CARRIQUE L, Quance J, Tan A, Abbey S, et al
    Results of Early Transplantation for Alcohol-Related Cirrhosis: Integrated Addiction Treatment with Low Rate of Relapse.
    Gastroenterology. 2021 Aug 6. pii: S0016-5085(21)03342.
    PubMed     Abstract available


    July 2021
  8. GE J, Pletcher MJ, Lai JC
    Outcomes of SARS-CoV-2 Infection in Patients with Chronic Liver Disease and Cirrhosis: a N3C Study.
    Gastroenterology. 2021 Jul 17. pii: S0016-5085(21)03244.
    PubMed     Abstract available


    May 2021
  9. EDWARDS LA, Goldenberg SD, Shawcross DL
    Meeting the challenge of antimicrobial resistance in cirrhosis: the invisible threat that lies within.
    Gastroenterology. 2021 May 25. pii: S0016-5085(21)03065.
    PubMed    


  10. GARCIA-TSAO G, Abraldes JG
    Non-selective beta-blockers in compensated cirrhosis: Preventing variceal hemorrhage or preventing decompensation?
    Gastroenterology. 2021 May 11. pii: S0016-5085(21)02972.
    PubMed    


    April 2021
  11. SHAMSADDINI A, Gillevet PM, Acharya C, Fagan A, et al
    Impact of Antibiotic Resistance Genes in Gut Microbiome of Patients with Cirrhosis.
    Gastroenterology. 2021 Apr 12. pii: S0016-5085(21)00634.
    PubMed     Abstract available


    March 2021
  12. ADENIJI N, Carr RM, Aby ES, Catana AM, et al
    Socioeconomic Factors Contribute to the Higher Risk of COVID-19 in Racial and Ethnic Minorities With Chronic Liver Diseases.
    Gastroenterology. 2021;160:1406-1409.
    PubMed    


  13. GOLDBERG D, Ross-Driscoll K, Lynch R
    County Differences in Liver Mortality in the United States: Impact of Sociodemographics, Disease Risk Factors, and Access to Care.
    Gastroenterology. 2021;160:1140-1150.
    PubMed     Abstract available


    February 2021
  14. YOUNOSSI ZM, Corey KE, Lim JK
    AGA Clinical Practice Update on Lifestyle Modification Using Diet and Exercise to Achieve Weight Loss in the Management of Nonalcoholic Fatty Liver Disease: Expert Review.
    Gastroenterology. 2021;160:912-918.
    PubMed     Abstract available


    January 2021
  15. ROCKEY DC, Friedman SL
    Fibrosis regression after eradication of hepatitis C virus - from bench to bedside.
    Gastroenterology. 2021 Jan 30. pii: S0016-5085(21)00330.
    PubMed     Abstract available


  16. PAIK JM, Younossi Y, Henry L, Mishra A, et al
    Recent Trends in the Global Burden of Hepatitis B virus (HBV): 2007-2017.
    Gastroenterology. 2021 Jan 6. pii: S0016-5085(21)00029.
    PubMed    


    December 2020
  17. EMDIN CA, Haas M, Ajmera V, Simon TG, et al
    Association of genetic variation with cirrhosis: a multi-trait genome-wide association and gene-environment interaction study.
    Gastroenterology. 2020 Dec 10. pii: S0016-5085(20)35545.
    PubMed     Abstract available


  18. YOUNOSSI ZM, Anstee QM, Wai-Sun Wong V, Trauner M, et al
    The Association of Histologic and Non-invasive Tests with Adverse Clinical and Patient-Reported Outcomes in Patients with Advanced Fibrosis Due to Nonalcoholic Steatohepatitis (NASH).
    Gastroenterology. 2020 Dec 8. pii: S0016-5085(20)35529.
    PubMed     Abstract available


  19. ARVIND A, Osganian SA, Sjoquist JA, Corey KE, et al
    Epoxygenase-Derived Epoxyeicosatrienoic Acid Mediators Are Associated With Nonalcoholic Fatty Liver Disease, Nonalcoholic Steatohepatitis, and Fibrosis.
    Gastroenterology. 2020;159:2232-2234.
    PubMed    


    November 2020
  20. HSU SJ, Zhang C, Jeong J, Lee SI, et al
    Enhanced meningeal lymphatic drainage ameliorates neuroinflammation and hepatic encephalopathy in cirrhotic rats.
    Gastroenterology. 2020 Nov 20. pii: S0016-5085(20)35439.
    PubMed     Abstract available


  21. NOUREDDIN M, Jones C, Alkhouri N, Gomez EV, et al
    Screening for Nonalcoholic Fatty Liver Disease in Persons with Type 2 Diabetes in the United States Is Cost-effective: A Comprehensive Cost-Utility Analysis.
    Gastroenterology. 2020;159:1985-1987.
    PubMed    


  22. LANG S, Demir M, Martin A, Jiang L, et al
    Intestinal Virome Signature Associated With Severity of Nonalcoholic Fatty Liver Disease.
    Gastroenterology. 2020;159:1839-1852.
    PubMed     Abstract available


    October 2020
  23. ASEEM SO, Jalan-Sakrikar N, Chi C, Navarro-Corcuera A, et al
    Epigenomic Evaluation of Cholangiocyte TGFbeta Signaling Identifies a Selective Role for Histone 3 Lysine 9 Acetylation in Biliary Fibrosis.
    Gastroenterology. 2020 Oct 12. pii: S0016-5085(20)35245.
    PubMed     Abstract available


  24. DE VRIES E, Bolier R, Goet J, Pares A, et al
    Fibrates for itch (FITCH) in fibrosing cholangiopathies: a double blind, randomized, placebo-controlled trial.
    Gastroenterology. 2020 Oct 5. pii: S0016-5085(20)35226.
    PubMed     Abstract available


  25. ROMEO S
    MARC1 and HNRNPUL1: Two Novel Players in Alcohol-related Liver Disease.
    Gastroenterology. 2020;159:1231-1232.
    PubMed    


    September 2020
  26. SOLE C, Guilly S, Da Silva K, Llopis M, et al
    ALTERATIONS IN GUT MICROBIOME IN CIRRHOSIS AS ASSESSED BY QUANTITATIVE METAGENOMICS. RELATIONSHIP WITH ACUTE-ON-CHRONIC LIVER FAILURE AND PROGNOSIS.
    Gastroenterology. 2020 Sep 14. pii: S0016-5085(20)35150.
    PubMed     Abstract available


    August 2020
  27. FLEMMING JA, Mullin M, Lu J, Sarkar MA, et al
    Outcomes of Pregnant Women With Cirrhosis and Their Infants in a Population-Based Study.
    Gastroenterology. 2020 Aug 8. pii: S0016-5085(20)35024.
    PubMed     Abstract available


  28. HARRISON SA, Neff G, Guy CD, Bashir MR, et al
    Efficacy and Safety of Aldafermin, an Engineered FGF19 Analog, in a Randomized, Double-Blind, Placebo-Controlled Trial of Patients With Nonalcoholic Steatohepatitis.
    Gastroenterology. 2020 Aug 8. pii: S0016-5085(20)35018.
    PubMed     Abstract available


  29. NABI O, Lacombe K, Boursier J, Mathurin P, et al
    Prevalence and Risk Factors of Nonalcoholic Fatty Liver Disease and Advanced Fibrosis in General Population: the French Nationwide NASH-CO Study.
    Gastroenterology. 2020;159:791-793.
    PubMed    


  30. SCHNEIDER CV, Hamesch K, Gross A, Mandorfer M, et al
    Liver Phenotypes of European Adults Heterozygous or Homozygous for Pi *Z Variant of AAT (Pi *MZ vs Pi *ZZ genotype) and Noncarriers.
    Gastroenterology. 2020;159:534-548.
    PubMed     Abstract available


  31. GUPTA V, Gupta I, Park J, Bram Y, et al
    Hedgehog Signaling Demarcates a Niche of Fibrogenic Peribiliary Mesenchymal Cells.
    Gastroenterology. 2020;159:624-638.
    PubMed     Abstract available


    July 2020
  32. BAJAJ JS, Reddy KR, O'Leary JG, Vargas HE, et al
    Serum Levels of Metabolites Produced by Intestinal Microbes and Lipid Moieties Independently Associated With Acute on Chronic Liver Failure and Death in Patients With Cirrhosis.
    Gastroenterology. 2020 Jul 17. pii: S0016-5085(20)34947.
    PubMed     Abstract available


    June 2020
  33. INNES H, Buch S, Hutchinson S, Guha IN, et al
    Genome-wide Association Study for Alcohol-related Cirrhosis Identifies Risk Loci in MARC1 and HNRNPUL1.
    Gastroenterology. 2020 Jun 16. pii: S0016-5085(20)34767.
    PubMed     Abstract available


  34. LASSAILLY G, Caiazzo R, Ntandja-Wandji LC, Gnemmi V, et al
    Bariatric Surgery Provides Long-term Resolution of Nonalcoholic Steatohepatitis and Regression of Fibrosis.
    Gastroenterology. 2020 Jun 15. pii: S0016-5085(20)34758.
    PubMed     Abstract available


    May 2020
  35. MAHMUD N, Hubbard RA, Kaplan DE, Serper M, et al
    Declining Cirrhosis Hospitalizations in the Wake of the COVID-19 Pandemic: A National Cohort Study.
    Gastroenterology. 2020 May 5. pii: S0016-5085(20)30597.
    PubMed    


  36. TAYLOR RS, Taylor RJ, Bayliss S, Hagstrom H, et al
    Association Between Fibrosis Stage and Outcomes of Patients With Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis.
    Gastroenterology. 2020;158:1611-1625.
    PubMed     Abstract available


  37. SCORLETTI E, Afolabi PR, Miles EA, Smith DE, et al
    Synbiotics Alter Fecal Microbiomes, But Not Liver Fat or Fibrosis, in a Randomized Trial of Patients With Nonalcoholic Fatty Liver Disease.
    Gastroenterology. 2020;158:1597-1610.
    PubMed     Abstract available


  38. GOLDNER D, Lavine JE
    Nonalcoholic Fatty Liver Disease in Children: Unique Considerations and Challenges.
    Gastroenterology. 2020;158:1967-1983.
    PubMed     Abstract available


  39. SCHWABE RF, Tabas I, Pajvani UB
    Mechanisms of Fibrosis Development in Nonalcoholic Steatohepatitis.
    Gastroenterology. 2020;158:1913-1928.
    PubMed     Abstract available


    April 2020
  40. NOUREDDIN M, Chan JL, Barradas K, Dimick-Santos L, et al
    Attribution of Nonalcoholic Steatohepatitis as an Etiology of Cirrhosis for Clinical Trials Eligibility: Recommendations from the Multi-stakeholder Liver Forum.
    Gastroenterology. 2020 Apr 27. pii: S0016-5085(20)30556.
    PubMed    


  41. PONTES AFECTO EM, Joao DA, Resende Rodrigues MA
    Unusual esophageal polyps in advanced cirrhosis.
    Gastroenterology. 2020 Apr 23. pii: S0016-5085(20)30559.
    PubMed    


  42. CARVAO J, Pereira VM, Jasmins L
    A case of unexplained cutaneous lesions, cholestatic hepatitis and non-cirrhotic portal hypertension in a female patient.
    Gastroenterology. 2020 Apr 16. pii: S0016-5085(20)30494.
    PubMed    


  43. KAMBOJ AK, Yung-Lun Chin J, Huebert RC
    A Curious Case of Confusion in a Patient with Cirrhosis.
    Gastroenterology. 2020 Apr 15. pii: S0016-5085(20)30513.
    PubMed    


    March 2020
  44. EL-SERAG HB, Kanwal F, Feng Z, Marrero JA, et al
    Risk Factors for Cirrhosis in Contemporary Hepatology Practices-Findings from Texas Hepatocellular Carcinoma Consortium Cohort.
    Gastroenterology. 2020 Mar 29. pii: S0016-5085(20)30403.
    PubMed    


  45. SAHIN-TOTH M
    Channelopathy of the pancreas causes chronic pancreatitis.
    Gastroenterology. 2020 Mar 20. pii: S0016-5085(20)30376.
    PubMed    


  46. MEJIAS M, Gallego J, Naranjo-Suarez S, Ramirez M, et al
    CPEB4 Increases Expression of PFKFB3 to Induce Glycolysis and Activate Mouse and Human Hepatic Stellate Cells, Promoting Liver Fibrosis.
    Gastroenterology. 2020 Mar 10. pii: S0016-5085(20)30328.
    PubMed     Abstract available


  47. KRUGER AJ
    Can macrophages in cirrhotic ascites fluid predict clinical outcome in SBP?
    Gastroenterology. 2020 Mar 2. pii: S0016-5085(20)30267.
    PubMed    


    January 2020
  48. STENGEL S, Quickert S, Lutz P, Ibidapo-Obe O, et al
    Peritoneal Level of CD206 Associates With Mortality and an Inflammatory Macrophage Phenotype in Patients With Decompensated Cirrhosis and Spontaneous Bacterial Peritonitis.
    Gastroenterology. 2020 Jan 23. pii: S0016-5085(20)30121.
    PubMed     Abstract available


  49. LIU X, Xu J, Rosenthal S, Zhang LJ, et al
    Identification of Lineage-specific Transcription Factors That Prevent Activation of Hepatic Stellate Cells and Promote Fibrosis Resolution.
    Gastroenterology. 2020 Jan 20. pii: S0016-5085(20)30117.
    PubMed     Abstract available


  50. LIN YH, Zhang S, Zhu M, Lu T, et al
    Mice With Increased Numbers of Polyploid Hepatocytes Maintain Regenerative Capacity but Develop Fewer Tumors Following Chronic Liver Injury.
    Gastroenterology. 2020 Jan 20. pii: S0016-5085(20)30116.
    PubMed     Abstract available


  51. HAGSTROM H, Talback M, Andreasson A, Walldius G, et al
    Ability of Noninvasive Scoring Systems to Identify Individuals in the Population at Risk for Severe Liver Disease.
    Gastroenterology. 2020;158:200-214.
    PubMed     Abstract available


    December 2019
  52. CHALASANI N, Abdelmalek MF, Garcia-Tsao G, Vuppalanchi R, et al
    Effects of Belapectin, an Inhibitor of Galectin-3, in Patients with Nonalcoholic Steatohepatitis With Cirrhosis And Portal Hypertension.
    Gastroenterology. 2019 Dec 5. pii: S0016-5085(19)41895.
    PubMed     Abstract available


    September 2019
  53. CHEUK-FUNG YIP T, Wai-Sun Wong V, Lik-Yuen Chan H, Tse YK, et al
    Tenofovir is Associated With Lower Risk of Hepatocellular Carcinoma Than Entecavir in Patients With Chronic HBV Infection in China.
    Gastroenterology. 2019 Sep 28. pii: S0016-5085(19)41367.
    PubMed     Abstract available


  54. DING X, He M, Chan AWH, Song QX, et al
    Genomic and Epigenomic Features of Primary and Recurrent Hepatocellular Carcinomas.
    Gastroenterology. 2019 Sep 24. pii: S0016-5085(19)41338.
    PubMed     Abstract available


  55. HAMESCH K, Mandorfer M, Pereira VM, Moeller LS, et al
    Liver Fibrosis and Metabolic Alterations in Adults With alpha-1-antitrypsin Deficiency Caused by the Pi*ZZ Mutation.
    Gastroenterology. 2019;157:705-719.
    PubMed     Abstract available


    July 2019
  56. FAN W, Liu T, Chen W, Hammad S, et al
    ECM1 Prevents Activation of Transforming Growth Factor beta, Hepatic Stellate Cells, and Fibrogenesis in Mice.
    Gastroenterology. 2019 Jul 27. pii: S0016-5085(19)41133.
    PubMed     Abstract available


  57. MORAN-SALVADOR E, Garcia-Macia M, Sivaharan A, Sabater L, et al
    Fibrogenic Activity of MECP2 is Regulated by Phosphorylation in Hepatic Stellate Cells.
    Gastroenterology. 2019 Jul 25. pii: S0016-5085(19)41126.
    PubMed     Abstract available


    June 2019
  58. SCHWIMMER JB, Johnson JS, Angeles JE, Behling C, et al
    Microbiome Signatures Associated with Steatohepatitis and Moderate to Severe Fibrosis in Children With Nonalcoholic Fatty Liver Disease.
    Gastroenterology. 2019 Jun 27. pii: S0016-5085(19)41037.
    PubMed     Abstract available


  59. YAN J, Tung HC, Li S, Niu Y, et al
    Aryl Hydrocarbon Receptor Signaling Prevents Activation of Hepatic Stellate Cells and Liver Fibrogenesis in Mice.
    Gastroenterology. 2019 Jun 3. pii: S0016-5085(19)40984.
    PubMed     Abstract available


    May 2019
  60. WIDJAJA AA, Singh BK, Adami E, Viswanathan S, et al
    Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Non-Alcoholic Steatohepatitis.
    Gastroenterology. 2019 May 8. pii: S0016-5085(19)40858.
    PubMed     Abstract available


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