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  Neoplasms of the CNS

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Articles published in J Neuropathol Exp Neurol

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Single Articles


    October 2024
  1. CECCHI R, Guptil D, Haslett N, Hristov A, et al
    Primary CNS histiocytic sarcoma: Two case reports highlighting a novel MIGA2::BRAF gene fusion and genome-wide DNA methylation profiling results.
    J Neuropathol Exp Neurol. 2024;83:882-886.
    PubMed    


    September 2024
  2. OHARA K, Al Assaad M, McNulty SN, Alnajar H, et al
    Detection of rare and novel gene fusions in patients with diffuse glioma: An institutional retrospective study.
    J Neuropathol Exp Neurol. 2024 Sep 28:nlae105. doi: 10.1093.
    PubMed    


  3. REIMANN RR, Gramatzki D, Bink A, Hench J, et al
    Long survival in a patient with fumarate hydratase mutation-associated glioma.
    J Neuropathol Exp Neurol. 2024 Sep 16:nlae100. doi: 10.1093.
    PubMed    


  4. KLEINSCHMIDT-DEMASTERS BK
    Mixed pituitary adenoma/pituitary neuroendocrine tumor-gangliocytoma: Immunohistochemical insights.
    J Neuropathol Exp Neurol. 2024;83:708-721.
    PubMed     Abstract available


  5. FENG Y, Wong PJC, Fu M, Kong Y, et al
    The comprehensive morphological and molecular characteristics of lipoastrocytoma: A case report.
    J Neuropathol Exp Neurol. 2024;83:785-790.
    PubMed    


    August 2024
  6. WANG C, Han H, Cheng F, Wang H, et al
    Clinical significance and potential mechanism of AEBP1 in glioblastoma.
    J Neuropathol Exp Neurol. 2024 Aug 27:nlae091. doi: 10.1093.
    PubMed     Abstract available


  7. TIAN S, Xie G, Zhang H, Zuo F, et al
    A heritable form of SMARCE1-related meningiomas with clinical implications.
    J Neuropathol Exp Neurol. 2024 Aug 19:nlae080. doi: 10.1093.
    PubMed    


  8. MORRIS M, Ararat K, Cutshall H, Gokden M, et al
    SMARCA4-deficient central nervous system metastases: A case series and systematic review.
    J Neuropathol Exp Neurol. 2024;83:638-654.
    PubMed     Abstract available


  9. ABOUBAKR O, Senova S, Kauv P, Castel D, et al
    A non-midline unclassified glioneuronal tumor with H3K27M mutation enlarging the spectrum of CNS tumors H3K27ME3-altered.
    J Neuropathol Exp Neurol. 2024;83:701-705.
    PubMed    


    July 2024
  10. TANAKA Y, Natsumeda M, Ohashi M, Saito R, et al
    Primary spinal cord gliomas: Pathologic features associated with prognosis.
    J Neuropathol Exp Neurol. 2024 Jul 29:nlae084. doi: 10.1093.
    PubMed     Abstract available


  11. ALTURKUSTANI M, Walker AD, Castaneda EA, Cotter JA, et al
    Utility of OLIG2 immunostaining in pediatric brain tumors with embryonal morphology.
    J Neuropathol Exp Neurol. 2024 Jul 27:nlae082. doi: 10.1093.
    PubMed     Abstract available


  12. KANATHANAVANICH M, Koga S, Stone SL, Roth J, et al
    CTDSP2::GLI1 fusion in glioblastoma: A diagnostic challenge through tumor heterogeneity.
    J Neuropathol Exp Neurol. 2024 Jul 9:nlae073. doi: 10.1093.
    PubMed    


  13. LE MK, Tran NQV, Nguyen PT, Nguyen TA, et al
    Comprehensive analysis of distinct circadian clock subtypes of adult diffuse glioma and their associations with clinicopathological, genetic, and epigenetic profiles.
    J Neuropathol Exp Neurol. 2024 Jul 4:nlae055. doi: 10.1093.
    PubMed     Abstract available


  14. FENG K, Ye G, Wang H, Li S, et al
    Research on the mechanism of TWSG1 in the malignant progression of glioma cells and tumor-associated macrophage infiltration.
    J Neuropathol Exp Neurol. 2024 Jul 1:nlae067. doi: 10.1093.
    PubMed     Abstract available


    June 2024
  15. KISELJAK-VASSILIADES K, Lipe K, Turin CG, Fishbein L, et al
    E-cadherin expression and gene expression profiles in corticotroph pituitary neuroendocrine tumor subtypes.
    J Neuropathol Exp Neurol. 2024;83:586-595.
    PubMed     Abstract available


  16. PARKER M, Kazemi F, Krishnakumar A, Horowitz MA, et al
    Availability and utilization of molecular testing for primary central nervous system tumors among US hospitals.
    J Neuropathol Exp Neurol. 2024;83:579-585.
    PubMed     Abstract available


  17. ZSCHERNACK V, Thomas C, Schaub C, Kristiansen G, et al
    FH-mutant glioma displaying the epigenetic signature of IDH-mutant astrocytomas.
    J Neuropathol Exp Neurol. 2024 Jun 14:nlae064. doi: 10.1093.
    PubMed    


  18. LORETO PALACIO P, Pan X, Jones D, Otero JJ, et al
    Exploring a distinct FGFR2::DLG5 rearrangement in a low-grade neuroepithelial tumor: A case report and mini-review of protein fusions in brain tumors.
    J Neuropathol Exp Neurol. 2024 Jun 4:nlae040. doi: 10.1093.
    PubMed     Abstract available


    May 2024
  19. SHIBAHARA I, Nakashima T, Toyoda M, Inukai M, et al
    Evolving driver mutations in adult-onset SHH-medulloblastoma originated from radiological cerebellar abnormality.
    J Neuropathol Exp Neurol. 2024 May 29:nlae051. doi: 10.1093.
    PubMed    


  20. VIZCAINO MA, Giannini C, Lalich D, Nael A, et al
    Ganglioglioma with anaplastic/high-grade transformation: Histopathologic, molecular, and epigenetic characterization of 3 cases.
    J Neuropathol Exp Neurol. 2024;83:416-424.
    PubMed     Abstract available


    April 2024
  21. MACRAE CB, Grieco KC, Solomon IH
    Diagnostic yield of postmortem brain examination following premortem brain biopsy for neoplastic and nonneoplastic disease.
    J Neuropathol Exp Neurol. 2024;83:331-337.
    PubMed     Abstract available


  22. WILCOCK DM, Goold E, Zuromski LM, Davidson C, et al
    EGFR/CEP7 high polysomy is separate and distinct from EGFR amplification in glioblastoma as determined by fluorescence in situ hybridization.
    J Neuropathol Exp Neurol. 2024 Apr 11:nlae028. doi: 10.1093.
    PubMed     Abstract available


    March 2024
  23. KALTER JA, Yang RA, Toland A, Milla S, et al
    IDH-mutant astrocytoma arising from a demyelinating plaque in a child with X-linked adrenoleukodystrophy.
    J Neuropathol Exp Neurol. 2024;83:289-292.
    PubMed    


  24. NEWMAN J, Leelatian N, Liang J
    Characterization of pediatric non-hematopoietic tumor metastases to the central nervous system: A single institution review.
    J Neuropathol Exp Neurol. 2024;83:268-275.
    PubMed     Abstract available


  25. DONEV K, Sundararajan V, Johnson D, Balan J, et al
    Diffuse hemispheric glioma with H3 p.K28M (K27M) mutation: Unusual non-midline presentation of diffuse midline glioma, H3 K27M-altered?
    J Neuropathol Exp Neurol. 2024 Mar 6:nlae018. doi: 10.1093.
    PubMed     Abstract available


    February 2024
  26. QI P, Yao QL, Lao IW, Ren M, et al
    A custom next-generation sequencing panel for 1p/19q codeletion and mutational analysis in gliomas.
    J Neuropathol Exp Neurol. 2024 Feb 26:nlae011. doi: 10.1093.
    PubMed     Abstract available


  27. KRAUSE KA, Woods JK, Golby AJ, Lee EQ, et al
    Progestin-associated meningiomatosis with unusual schwannoma-like morphology.
    J Neuropathol Exp Neurol. 2024 Feb 1:nlae008. doi: 10.1093.
    PubMed    


    January 2024
  28. XI S, Huang Q, Zeng J
    A novel grading system combining histological grade and CDKN2A homozygous and hemizygous deletion to predict prognosis in IDH-mutant astrocytoma.
    J Neuropathol Exp Neurol. 2024;83:125-130.
    PubMed     Abstract available


  29. FENG Y, Xu H, Hu X, Zhang J, et al
    Heterogenous driving genetic events contribute to the dissemination of choroid plexus papilloma.
    J Neuropathol Exp Neurol. 2024;83:131-135.
    PubMed    


  30. MARIET C, Grill J, Ajlil Y, Castel D, et al
    "Hemispheric pilocytic astrocytoma" revisited: A comprehensive clinicopathological and molecular series emphasizing their overlap with other glioneuronal tumors.
    J Neuropathol Exp Neurol. 2024;83:115-124.
    PubMed     Abstract available


  31. ABOUBAKR O, Metais A, Doz F, Saffroy R, et al
    LEF-1 immunohistochemistry, a better diagnostic biomarker than beta-catenin for medulloblastoma, WNT-activated subtyping.
    J Neuropathol Exp Neurol. 2024 Jan 17:nlad104. doi: 10.1093.
    PubMed    


  32. GUBBIOTTI MA, Weinberg JS, Weathers SP, Dasgupta P, et al
    An incidental finding of a high-grade glioma with pleomorphic and pseudopapillary features (HPAP) with PBRM1 mutation.
    J Neuropathol Exp Neurol. 2024 Jan 2:nlad114. doi: 10.1093.
    PubMed    


    December 2023
  33. ROBINSON LJ, Goold E, Potter S, Quigley EP, et al
    A pleomorphic xanthoastrocytoma highlighting the morphological heterogeneity of this uncommon tumor.
    J Neuropathol Exp Neurol. 2023;83:61-64.
    PubMed    


  34. GUNDOGDU F, Babaoglu B, Soylemezoglu F
    Reliability assessment of methylthioadenosine phosphorylase immunohistochemistry as a surrogate biomarker for CDKN2A homozygous deletion in adult-type IDH-mutant diffuse gliomas.
    J Neuropathol Exp Neurol. 2023 Dec 18:nlad109. doi: 10.1093.
    PubMed     Abstract available


    November 2023
  35. GESTRICH C, Grieco K, Lidov HG, Baird LC, et al
    H3K27-altered diffuse midline gliomas with MAPK pathway alterations: Prognostic and therapeutic implications.
    J Neuropathol Exp Neurol. 2023 Nov 30:nlad103. doi: 10.1093.
    PubMed     Abstract available


  36. HUA Y, Youens KE, Castro E, Wang D, et al
    Autopsy findings in a 6-month-old infant with rhabdoid tumor predisposition syndrome 1: Case report with literature review.
    J Neuropathol Exp Neurol. 2023;82:1040-1043.
    PubMed    


  37. WHITE B, Filo J, Orrego-Gonzalez E, Schwartz SN, et al
    Synchronous contralateral low-grade oligodendroglioma and high-grade IDH-mutant astrocytoma.
    J Neuropathol Exp Neurol. 2023;82:1048-1050.
    PubMed    


  38. NUECHTERLEIN N, Shelbourn A, Cimino PJ
    Whole gain of chromosome 19, not co-gain of chromosomes 19 and 20, characterizes a class of glioblastomas with more favorable outcomes.
    J Neuropathol Exp Neurol. 2023 Nov 14:nlad092. doi: 10.1093.
    PubMed    


  39. BLUM N, Mirian C, Maier AD, Mathiesen TI, et al
    Translocator protein (TSPO) expression in neoplastic cells and tumor-associated macrophages in meningiomas.
    J Neuropathol Exp Neurol. 2023 Nov 11:nlad093. doi: 10.1093.
    PubMed     Abstract available


    October 2023
  40. NAZEM A, Lavezo J, Abdullaev Z, Aldape K, et al
    Diffuse hemispheric glioma with H3-3B G34R mutation: Expanding the spectrum of histone H3 genes in diffuse hemispheric glioma, H3 G34-mutant.
    J Neuropathol Exp Neurol. 2023 Oct 25:nlad089. doi: 10.1093.
    PubMed    


  41. ABOUBAKR O, Metais A, Hasty L, Saffroy R, et al
    Brainstem oligodendroglioma, IDH-mutant, and 1P/19Q-codeleted: A potential diagnostic pitfall.
    J Neuropathol Exp Neurol. 2023;82:958-962.
    PubMed    


  42. CAO C, Zhang L, Sorensen MD, Reifenberger G, et al
    D-2-hydroxyglutarate regulates human brain vascular endothelial cell proliferation and barrier function.
    J Neuropathol Exp Neurol. 2023;82:921-933.
    PubMed     Abstract available


  43. SHELBOURN A, Nuechterlein N, Parada CA, Eaton J, et al
    Validating MCM2 as a clinically relevant surrogate immunohistochemical marker for an aggressive meningioma molecular subtype.
    J Neuropathol Exp Neurol. 2023 Oct 13:nlad082. doi: 10.1093.
    PubMed    


  44. KOLEILAT A, Kumar V, Al Hmada Y, Milosevic D, et al
    Concurrent TERT promoter C228T and C250T mutations in diffuse gliomas: Rare occurrence of intratumoral heterogeneity.
    J Neuropathol Exp Neurol. 2023 Oct 9:nlad081. doi: 10.1093.
    PubMed    


    September 2023
  45. XU E, Stone SL, Zhong Y, Golenberg N, et al
    A novel ARIH1::BRAF fusion in a glioma.
    J Neuropathol Exp Neurol. 2023 Sep 23:nlad074. doi: 10.1093.
    PubMed    


  46. ZHANG Y, Huang H, Liu P, Xie Y, et al
    NFYB increases chemosensitivity in glioblastoma by promoting HDAC5-mediated transcriptional inhibition of SHMT2.
    J Neuropathol Exp Neurol. 2023 Sep 23:nlad073. doi: 10.1093.
    PubMed     Abstract available


  47. YOKODA RT, Cobb WS, Yong RL, Crary JF, et al
    CDKN2A mutations have equivalent prognostic significance to homozygous deletion in IDH-mutant astrocytoma.
    J Neuropathol Exp Neurol. 2023;82:845-852.
    PubMed     Abstract available


    June 2023
  48. GUBBIOTTI MA, Madsen PJ, Tucker AM, Abdullaev Z, et al
    ZFTA-fused supratentorial ependymoma with a novel fusion partner, DUX4.
    J Neuropathol Exp Neurol. 2023;82:668-671.
    PubMed    


  49. MAIER AD, Christiansen SN, Haslund-Vinding J, Krogager ME, et al
    DNA methylation profile of human dura and leptomeninges.
    J Neuropathol Exp Neurol. 2023;82:641-649.
    PubMed     Abstract available


  50. FUKUOKA K, Nakazawa A, Hirato J, Nobusawa S, et al
    An infantile pineal embryonal tumor showing pathological features of a CNS ganglioneuroblastoma and the methylation profiling of an atypical teratoid/rhabdoid tumor and SMARCA4 mutation.
    J Neuropathol Exp Neurol. 2023;82:664-667.
    PubMed    


  51. BROGGI G, Barresi V
    Assessment of CDKN2A/B homozygous deletion in gliomas: To FISH or not to FISH?
    J Neuropathol Exp Neurol. 2023 Jun 12:nlad045. doi: 10.1093.
    PubMed    


    May 2023
  52. LE MK, Vuong HG, Nguyen TTT, Kondo T, et al
    NAA10 overexpression dictates distinct epigenetic, genetic, and clinicopathological characteristics in adult gliomas.
    J Neuropathol Exp Neurol. 2023 May 30:nlad037. doi: 10.1093.
    PubMed     Abstract available


  53. LIU X, Zhao J, Wu Q, Wang L, et al
    ANKRD22 promotes glioma proliferation, migration, invasion, and epithelial-mesenchymal transition by upregulating E2F1-mediated MELK expression.
    J Neuropathol Exp Neurol. 2023 May 10:nlad034. doi: 10.1093.
    PubMed     Abstract available


    April 2023
  54. GUBBIOTTI MA, Dhillon KS, Harris J, Kothari S, et al
    An unusual case of metastatic diffuse midline glioma in an adult.
    J Neuropathol Exp Neurol. 2023 Apr 19:nlad032. doi: 10.1093.
    PubMed    


  55. YANG X, Ye Z, Zhang M, Ouyang Y, et al
    Tissue clearing to examine glioma complexity in 3 dimensions.
    J Neuropathol Exp Neurol. 2023 Apr 6:nlad024. doi: 10.1093.
    PubMed     Abstract available


    March 2023
  56. PERSONS JE, Eschbacher KL
    A case of dedifferentiated meningeal solitary fibrous tumor.
    J Neuropathol Exp Neurol. 2023;82:367-369.
    PubMed    


  57. CONG H, Guo X, Fan B, Liu Y, et al
    Dimethylation of histone H3 lysine 36 (H3K36me2) as a potential biomarker for glioma diagnosis, grading, and prognosis.
    J Neuropathol Exp Neurol. 2023 Mar 15:nlad016. doi: 10.1093.
    PubMed     Abstract available


  58. BRANDEL MG, Goodwill VS, Park A, Snyder V, et al
    Sudden unexpected death from hydrocephalus due to cerebellopontine angle meningioma.
    J Neuropathol Exp Neurol. 2023 Mar 2:nlad014. doi: 10.1093.
    PubMed    


    February 2023
  59. JUNGO P, Hewer E
    Code-free machine learning for classification of central nervous system histopathology images.
    J Neuropathol Exp Neurol. 2023;82:221-230.
    PubMed     Abstract available


  60. GUBBIOTTI MA, Santi M, Storm PB, Li M, et al
    First-time identification of a KIF5B-NTRK2 fusion in extraventricular neurocytoma.
    J Neuropathol Exp Neurol. 2023;82:272-275.
    PubMed    


  61. KLEINSCHMIDT-DEMASTERS BK, Ormond DR
    Leptomeningeal metastases and dural spread in adult high-grade astrocytomas.
    J Neuropathol Exp Neurol. 2023;82:194-201.
    PubMed     Abstract available


  62. KANG MK, Ahn SJ, Ha J, Park SH, et al
    Natural killer T-cell primary CNS lymphoma presenting as lymphomatosis cerebri: a case report and literature review.
    J Neuropathol Exp Neurol. 2023;82:261-266.
    PubMed    


    January 2023
  63. SUH YY, Lee K, Shim YM, Phi JH, et al
    MYB/MYBL1::QKI fusion-positive diffuse glioma.
    J Neuropathol Exp Neurol. 2023 Jan 2:nlac123. doi: 10.1093.
    PubMed     Abstract available


    November 2022
  64. NORRIS GA, Willard N, Donson AM, Gaskell A, et al
    PDGFB:APOBEC3C fusion in congenital diffuse high-grade glioma of the brainstem.
    J Neuropathol Exp Neurol. 2022 Nov 28:nlac112. doi: 10.1093.
    PubMed    


  65. OULD ISMAIL AA, Parra O, Hughes EG, Green DC, et al
    Novel FGFR2::ZCCHC24 Fusion in Dysembryoplastic Neuroepithelial Tumor.
    J Neuropathol Exp Neurol. 2022;81:1029-1032.
    PubMed    


  66. VIZCAINO MA, Giannini C, King RL, Johnson DR, et al
    Primary Leptomeningeal Lymphoma: Clinicopathologic Features of 2 Rare Phenotypes.
    J Neuropathol Exp Neurol. 2022;81:1002-1007.
    PubMed     Abstract available


  67. RAGHUNATHAN A, Ida CM, Westbroek EM, Gupta S, et al
    Mutations of FH and IDH may induce gliomagenesis by similar mechanisms.
    J Neuropathol Exp Neurol. 2022 Nov 11. pii: 6823866. doi: 10.1093.
    PubMed    


  68. TREJO-LOPEZ JA, Praska CE, Zepeda Mendoza C, Kollmeyer TM, et al
    H3 G34 mutation assessment for diffuse gliomas in adults: when would testing be most diagnostically useful?
    J Neuropathol Exp Neurol. 2022 Nov 3. pii: 6795064. doi: 10.1093.
    PubMed    


    October 2022
  69. AHRENDSEN JT, Freund RS, Hsu N, Bryke C, et al
    Cytogenetic and Molecular Characterization of IDH-Wildtype Glioblastomas and Grade 4 IDH-Mutant Astrocytomas with Unusual Histology.
    J Neuropathol Exp Neurol. 2022 Oct 18. pii: 6762949. doi: 10.1093.
    PubMed     Abstract available


  70. LEROND J, Morisse MC, Letourneur Q, Gimonnet C, et al
    Immune Microenvironment and Lineage Tracing Help to Decipher Rosette-Forming Glioneuronal Tumors: A Multi-Omics Analysis.
    J Neuropathol Exp Neurol. 2022;81:873-884.
    PubMed     Abstract available


  71. SHIVELY SB, Edwards NA, MacDonald TJ, Johnson KR, et al
    Developmentally Arrested Basket/Stellate Cells in Postnatal Human Brain as Potential Tumor Cells of Origin for Cerebellar Hemangioblastoma in von Hippel-Lindau Patients.
    J Neuropathol Exp Neurol. 2022;81:885-899.
    PubMed     Abstract available


    September 2022
  72. TUBRE T, Hacking S, Alexander A, Brickman A, et al
    Prostate-Specific Membrane Antigen Expression in Meningioma: A Promising Theranostic Target.
    J Neuropathol Exp Neurol. 2022 Sep 30. pii: 6732413. doi: 10.1093.
    PubMed     Abstract available


  73. HEIN AL, Cathcart SJ, Cushman-Vokoun A, Shonka NA, et al
    EGFR Exon 20 Insertion in Bithalamic and Unithalamic Glioma: A Report of 2 Cases and Literature Review.
    J Neuropathol Exp Neurol. 2022 Sep 12. pii: 6696214. doi: 10.1093.
    PubMed    


    August 2022
  74. BERRY JF, Vidrine DW, Wojcik AA, Trivedi D, et al
    Glioblastoma, IDH-Wildtype Harboring a KIAA1549::BRAF Fusion: Report of a Case With Comprehensive Molecular Profiling.
    J Neuropathol Exp Neurol. 2022 Aug 27. pii: 6678072. doi: 10.1093.
    PubMed    


  75. GARCIA MR, Feng Y, Vasudevaraja V, Galbraith K, et al
    Clinical, Pathological, and Molecular Characteristics of Diffuse Spinal Cord Gliomas.
    J Neuropathol Exp Neurol. 2022 Aug 23. pii: 6673886. doi: 10.1093.
    PubMed     Abstract available


  76. LEELATIAN N, Goss J, Pastakia D, Dewan MC, et al
    Primary Intracranial Sarcoma, DICER1-Mutant Presenting as a Pineal Region Tumor Mimicking Pineoblastoma: Case Report and Review of the Literature.
    J Neuropathol Exp Neurol. 2022;81:762-764.
    PubMed    



  77. Correction to: Basal Recess in Third Ventricle Tumors: A Pathological Feature Defining a Clinical-Topographical Subpopulation of Papillary Craniopharyngiomas.
    J Neuropathol Exp Neurol. 2022 Aug 13. pii: 6665892. doi: 10.1093.
    PubMed    


    July 2022
  78. MO H, Magaki S, Deisch JK, Raghavan R, et al
    Isocitrate Dehydrogenase Mutations Are Associated with Different Expression and DNA Methylation Patterns of OLIG2 in Adult Gliomas.
    J Neuropathol Exp Neurol. 2022 Jul 20. pii: 6647005. doi: 10.1093.
    PubMed     Abstract available


  79. LUCAS CG, Davidson CJ, Alashari M, Putnam AR, et al
    Targeted Next-Generation Sequencing Reveals Divergent Clonal Evolution in Components of Composite Pleomorphic Xanthoastrocytoma-Ganglioglioma.
    J Neuropathol Exp Neurol. 2022;81:650-657.
    PubMed     Abstract available


    June 2022

  80. Correction to: Tumor-Derived Cell Culture Model for the Investigation of Meningioma Biology.
    J Neuropathol Exp Neurol. 2022 Jun 17. pii: 6613581. doi: 10.1093.
    PubMed    


    May 2022
  81. LIU C, Chen X, Zhang L, Liu J, et al
    F-Box Protein 11 Suppresses Cell Proliferation and Aerobic Glycolysis in Glioblastomas by Mediating the Ubiquitin Degradation of Cdc25A.
    J Neuropathol Exp Neurol. 2022 May 18. pii: 6587358. doi: 10.1093.
    PubMed     Abstract available


  82. TUNA G, Dal-Bekar NE, Akay A, Ruksen M, et al
    Minimally Invasive Detection of IDH1 Mutation With Cell-Free Circulating Tumor DNA and D-2-Hydroxyglutarate, D/L-2-Hydroxyglutarate Ratio in Gliomas.
    J Neuropathol Exp Neurol. 2022 May 18. pii: 6587360. doi: 10.1093.
    PubMed     Abstract available


    April 2022
  83. PASCUAL JM, Prieto R, Carrasco R, Barrios L, et al
    Basal Recess in Third Ventricle Tumors: A Pathological Feature Defining a Clinical-Topographical Subpopulation of Papillary Craniopharyngiomas.
    J Neuropathol Exp Neurol. 2022 Apr 26. pii: 6574454. doi: 10.1093.
    PubMed     Abstract available


  84. SAHU U, Barth RF, Otani Y, McCormack R, et al
    Rat and Mouse Brain Tumor Models for Experimental Neuro-Oncology Research.
    J Neuropathol Exp Neurol. 2022 Apr 21. pii: 6572007. doi: 10.1093.
    PubMed     Abstract available


    March 2022
  85. TROY C, Gill BJA, Miller ML, Hickman RA, et al
    Adenocarcinoma Arising in a Yolk Sac Tumor of the Pineal Gland.
    J Neuropathol Exp Neurol. 2022;81:291-295.
    PubMed    


  86. VALERIO E, Alves de Castro JV, Carraro DM, Torrezan GT, et al
    Beyond Midline: Diffuse Hemispheric Glioma, H3 K27M-Mutant with Aggressive Behavior.
    J Neuropathol Exp Neurol. 2022 Mar 18. pii: 6550548. doi: 10.1093.
    PubMed    


    February 2022
  87. TOGNI C, Rom E, Burghardt I, Roth P, et al
    Prognostic Relevance of Transforming Growth Factor-beta Receptor Expression and Signaling in Glioblastoma, Isocitrate Dehydrogenase-Wildtype.
    J Neuropathol Exp Neurol. 2022;81:225-235.
    PubMed     Abstract available


    January 2022
  88. BITAR M, Chornenkyy Y, Flanagan ME, Steffens A, et al
    The Frequency of Focal Cortical Dysplasia-Like Histologic Features Near Adult-Type Diffuse Gliomas.
    J Neuropathol Exp Neurol. 2022;81:48-53.
    PubMed     Abstract available


  89. ABOUBAKR O, Metais A, Berthaud C, Gigant P, et al
    L1CAM Is Not a Reliable Diagnostic Biomarker for Distinguishing Supratentorial Ependymomas, ZFTA Fusion-Positive From Other Central Nervous System Tumors.
    J Neuropathol Exp Neurol. 2022;81:82-85.
    PubMed    


  90. ONYENEKWU CP, Cunningham AM, Schilter K, Reddi HV, et al
    Diffuse Leptomeningeal Histiocytic Sarcoma: Histologic and Molecular Findings in an Autopsy Case.
    J Neuropathol Exp Neurol. 2022;81:79-81.
    PubMed    


  91. VIZCAINO MA, Kurtin PJ, King RL, Spinner RJ, et al
    Diffuse Large B-Cell Lymphoma of Peripheral Nerve with Distinctive Pathological Features Resembling Primary CNS Lymphoma.
    J Neuropathol Exp Neurol. 2022;81:76-78.
    PubMed    


    December 2021
  92. KRONISH A, DeNardo B, Kanach C, Lulla RR, et al
    Activating BRAF G469A Missense Mutation in a Pediatric Patient With High-Grade Glioma.
    J Neuropathol Exp Neurol. 2021;80:1141-1142.
    PubMed    


  93. KIMURA T, Ikedo T, Ohta-Ogo K, Hamano E, et al
    A Pathologically Verified Case of Peripheral Intracranial Aneurysmal Formation With Massively Infiltrating Meningioma Cells.
    J Neuropathol Exp Neurol. 2021 Dec 29. pii: 6487232. doi: 10.1093.
    PubMed    


  94. SASAKI S, Takeda M, Hirose T, Fujii T, et al
    Correlation of MTAP Immunohistochemistry With CDKN2A Status Assessed by Fluorescence In Situ Hybridization and Clinicopathological Features in CNS WHO Grade 2 and 3 Meningiomas: A Single Center Cohort Study.
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    PubMed     Abstract available


  95. ROSAGER AM, Dahlrot RH, Sorensen MD, Bangso JA, et al
    The Epigenetic Regulator Jumonji Domain-Containing Protein 6 (JMJD6) Is Highly Expressed but Not Prognostic in IDH-Wildtype Glioblastoma Patients.
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    PubMed     Abstract available


  96. LARKIN CJ, Jennings LJ, Heimberger AB, Horbinski C, et al
    Next-Generation Sequencing of a Glioblastoma with True Epithelial Differentiation.
    J Neuropathol Exp Neurol. 2021 Dec 3. pii: 6448594. doi: 10.1093.
    PubMed    


    November 2021
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    Tumor-Derived Cell Culture Model for the Investigation of Meningioma Biology.
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  98. LIND KT, Chatwin HV, DeSisto J, Coleman P, et al
    Novel RAF Fusions in Pediatric Low-Grade Gliomas Demonstrate MAPK Pathway Activation.
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  99. CHKHEIDZE R, Raisanen J, Gagan J, Richardson TE, et al
    Alterations in the RB Pathway With Inactivation of RB1 Characterize Glioblastomas With a Primitive Neuronal Component.
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    PubMed     Abstract available


  100. KLEINSCHMIDT-DEMASTERS BK
    Metastases to the Pituitary Gland: Histological Patterns of Spread and Review of the Literature.
    J Neuropathol Exp Neurol. 2021;80:1033-1042.
    PubMed     Abstract available


    October 2021
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    An Unusual Ganglioglioma with Pseudopapillary Features and PRKAR2B-BRAF Fusion.
    J Neuropathol Exp Neurol. 2021;80:1000-1003.
    PubMed    


  102. LIN CC, Mansukhani MM, Bruce JN, Canoll P, et al
    Rosette-Forming Glioneuronal Tumor in the Pineal Region: A Series of 6 Cases and Literature Review.
    J Neuropathol Exp Neurol. 2021;80:933-943.
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    Papillary Glioneuronal Tumor With a Novel GPR37L1-PRKCA Fusion.
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    PubMed    


    September 2021
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    Molecular Alterations in Pediatric Low-Grade Gliomas That Led to Death.
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    PubMed     Abstract available


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    Expression of STAT6 and Phosphorylated STAT6 in Primary Central Nervous System Lymphomas.
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  106. LIN CC, Lefferts JA, Chan AM, Zanazzi G, et al
    Rare Activating BRAF Alteration Involving the beta3-alphaC Kinase Domain in Ganglioglioma.
    J Neuropathol Exp Neurol. 2021;80:887-889.
    PubMed    


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    Molecular Alterations in Meningioangiomatosis Causing Epilepsy.
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    PubMed     Abstract available


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    Pediatric Gliomas Presenting with Gliomatosis-Like Spread, Lack of Contrast Enhancement, EGFR Mutation, and TERT Promoter Variants.
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    PubMed    


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    Bioengineered Models to Study Microenvironmental Regulation of Glioblastoma Metabolism.
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    PubMed     Abstract available


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    Primary Nondural Central Nervous System Marginal ZoneB-Cell Lymphoma of the Mucosa-Associated Lymphoid Tissue Type Mimicking CNS Inflammatory Diseases.
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    PubMed     Abstract available


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    Nuclear IMPDH Filaments in Human Gliomas.
    J Neuropathol Exp Neurol. 2021 Sep 8. pii: 6366485. doi: 10.1093.
    PubMed     Abstract available


    August 2021
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    A Rare Presentation of Low-Grade Prostate Adenocarcinoma as Delayed Pineal Region Metastasis: A Case Report and Review of Multicenter Clinical Experience in Prostate Carcinoma Brain Metastases.
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    PubMed    


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    Analyses of DNA Methylation Profiling in the Diagnosis of Intramedullary Astrocytomas.
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    PubMed     Abstract available


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    Primary Epithelioid Hemangioma of the Central Nervous System: A Case Report and Review of the Literature.
    J Neuropathol Exp Neurol. 2021;80:717-719.
    PubMed    


    July 2021
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    MicroRNA Dysregulation in Canine Meningioma: RT-qPCR Analysis of Formalin-Fixed Paraffin-Embedded Samples.
    J Neuropathol Exp Neurol. 2021 Jul 17. pii: 6323287. doi: 10.1093.
    PubMed     Abstract available


  116. PROSNIAK M, Kenyon LC, Hooper DC
    Glioblastoma Contains Topologically Distinct Proliferative and Metabolically Defined Subpopulations of Nestin- and Glut1-Expressing Cells.
    J Neuropathol Exp Neurol. 2021 Jul 16. pii: 6322918. doi: 10.1093.
    PubMed     Abstract available


    June 2021
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    Sarcomatous Meningioma: Diagnostic Pitfalls and the Utility of Molecular Testing.
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    May 2021
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    Expression and Prognostic Value of the Immune Checkpoints Galectin-9 and PD-L1 in Glioblastomas.
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  119. HIRAKI T, Fukuoka K, Mori M, Arakawa Y, et al
    Application of Genome-Wide DNA Methylation Analysis to Differentiate a Case of Radiation-Induced Glioblastoma From Late-Relapsed Medulloblastoma.
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    April 2021
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    Medulloblastoma in Adults: Cytogenetic Phenotypes Identify Prognostic Subgroups.
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    What Every Neuropathologist Needs to Know: Practical Aspects and Pitfalls in Molecular Diagnosis of Brain Tumors.
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    March 2021
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    NTRK Fusions Can Co-Occur With H3K27M Mutations and May Define Druggable Subclones Within Diffuse Midline Gliomas.
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    Molecular Signatures of Chromosomal Instability Correlate With Copy Number Variation Patterns and Patient Outcome in IDH-Mutant and IDH-Wildtype Astrocytomas.
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    Heterogeneous Pattern of Differentiation With BCAS1/NABC1 Expression in a Case of Oligodendroglioma.
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    PubMed    


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    Novel Glutamine Antagonist JHU395 Suppresses MYC-Driven Medulloblastoma Growth and Induces Apoptosis.
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    February 2021
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    Comment on: SMARCB1 Gene Mutation Predisposes to Earlier Development of Glioblastoma: A Case Report of Familial GBM.
    J Neuropathol Exp Neurol. 2021;80:289-290.
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    Authors' Reply: SMARCB1 Gene Mutation Predisposes to Earlier Development of Glioblastoma: A Case Report of Familial GBM.
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    IDH-Mutant Astrocytoma With Chromosome 19q13 Deletion Manifesting as an Oligodendroglioma-Like Morphology.
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    Spinal Cord Pilocytic Astrocytoma With FGFR1-TACC1 Fusion and Anaplastic Transformation.
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    Non-canonical IDH Mutation Frequency in IDH1-R132H-Negative Glioblastoma Patients Older Than 54 Years.
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    January 2021
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    Subependymal Giant Cell Astrocytoma in a 79-Year-Old Woman without Clinical Features of Tuberous Sclerosis: A Case Report.
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    Spatially Resolved and Quantitative Analysis of the Immunological Landscape in Human Meningiomas.
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    Clinical-Pathological, Immunohistochemical, and Genetic Characterization of a Series of Posterior Pituitary Tumors.
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    Intra-Axial Frontal Cyst with Ependymoma-Like Proliferation: Neuroectodermal or Neurenteric?
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    December 2020
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    Glioma-Derived TSP2 Promotes Excitatory Synapse Formation and Results in Hyperexcitability in the Peritumoral Cortex of Glioma.
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    Clinical Aggressiveness of TP53-Wild Type Sonic Hedgehog Medulloblastoma With MYCN Amplification, Chromosome 17p Loss, and Chromothripsis.
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    Epithelioid Pituicytoma: Expanding the Morphologic Spectrum of a Rare Neoplasm.
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    November 2020
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    GLI3 Is Associated With Neuronal Differentiation in SHH-Activated and WNT-Activated Medulloblastoma.
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    Tumor-Infiltrating Lymphocytes Are Enriched in Nonhypoxic Glioblastoma Niches.
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    PRKCA D463H Mutation in Chordoid Glioma of the Third Ventricle: A Cohort of 16 Cases, Including Two Cases Harboring BRAFV600E Mutation.
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    Broadening the Age of Incidence of Intracranial Angiomatoid Fibrous Histiocytoma With EWSR1-CREM Fusion: A Case Report.
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    Identification of a Novel BRCA1 Alteration in Recurrent Melanocytoma Resulting in Increased Proliferation.
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    Overexpression of Long Noncoding RNA HOTAIR Is a Unique Epigenetic Characteristic of Myxopapillary Ependymoma.
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    October 2020
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    Myxoid Meningioma: First Report of a Rare Metaplastic Meningioma Variant in the Pineal Region.
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    Anaplastic Transformation in Myxopapillary Ependymoma: A Report of 2 Cases and Review of the Literature.
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    September 2020
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    Acquired ATRX Loss and ALT Phenotype Through Tumor Recurrences in a Case of Pleomorphic Xanthoastrocytoma Suggest Their Possible Roles in Tumor Progression.
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    August 2020
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    Pineal Region High-Grade Glioneuronal Tumor With a Novel ZBTB10-NTRK3 Fusion.
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    Exploring DNA Methylation for Prognosis and Analyzing the Tumor Microenvironment in Pleomorphic Xanthoastrocytoma.
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    July 2020
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    Primary CNS CD45-Depleted T-Cell Lymphoma: The First Pathologically Confirmed Case.
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    MEK Inhibition Suppresses Growth of Atypical Teratoid/Rhabdoid Tumors.
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