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Articles published in Neuro Oncol

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Single Articles


    November 2018
  1. NARITA Y, Arakawa Y, Yamasaki F, Nishikawa R, et al
    A randomized, double-blind, phase III trial of personalized peptide vaccination for recurrent glioblastoma.
    Neuro Oncol. 2018 Nov 30. pii: 5219198. doi: 10.1093.
    PubMed     Text format     Abstract available


  2. BALE TA, Jordan JT, Rapalino O, Ramamurthy N, et al
    Financially Effective Test-Algorithm to Identify an Aggressive, EGFR-amplified Variant of IDH-Wildtype, Lower-Grade Diffuse Glioma.
    Neuro Oncol. 2018 Nov 28. pii: 5212363. doi: 10.1093.
    PubMed     Text format     Abstract available


  3. LUDMIR EB, Mandel JJ, McAleer MF, de Groot JF, et al
    Disparities along the glioblastoma clinical trials landscape.
    Neuro Oncol. 2018 Nov 26. pii: 5209731. doi: 10.1093.
    PubMed     Text format    


  4. DI STEFANO AL, Savatovsky J, Feuvret L, Villa C, et al
    CNS inflammatory disorder after concurrent radiotherapy-temozolomide and nivolumab in a glioblastoma patient.
    Neuro Oncol. 2018 Nov 23. pii: 5203543. doi: 10.1093.
    PubMed     Text format    


  5. HORBINSKI C
    Differences in molecular profiles of glioblastomas according to location.
    Neuro Oncol. 2018 Nov 15. pii: 5183524. doi: 10.1093.
    PubMed     Text format    


  6. SCHIFF D, de Groot JF
    Lower-grade gliomas: the wrong target for bevacizumab.
    Neuro Oncol. 2018;20:1559-1560.
    PubMed     Text format    


  7. SPERDUTO PW, Deegan BJ, Li J, Jethwa KR, et al
    Estimating survival for renal cell carcinoma patients with brain metastases: an update of the Renal Graded Prognostic Assessment tool.
    Neuro Oncol. 2018;20:1652-1660.
    PubMed     Text format     Abstract available


  8. EISEMANN T, Costa B, Harter PN, Wick W, et al
    Podoplanin expression is a prognostic biomarker but may be dispensable for the malignancy of glioblastoma.
    Neuro Oncol. 2018 Nov 10. pii: 5168873. doi: 10.1093.
    PubMed     Text format     Abstract available


  9. PRABHU AH, Kant S, Kesarwani P, Ahmed K, et al
    Integrative cross-platform analyses identify enhanced heterotrophy as a metabolic hallmark in glioblastoma.
    Neuro Oncol. 2018 Nov 10. pii: 5172259. doi: 10.1093.
    PubMed     Text format     Abstract available


  10. AQUILANTI E, Miller J, Santagata S, Cahill DP, et al
    Updates in prognostic markers for gliomas.
    Neuro Oncol. 2018;20.
    PubMed     Text format     Abstract available


    October 2018
  11. DIPLAS BH, Liu H, Yang R, Hansen LJ, et al
    Sensitive and rapid detection of TERT promoter and IDH mutations in diffuse gliomas.
    Neuro Oncol. 2018 Oct 22. pii: 5140128. doi: 10.1093.
    PubMed     Text format     Abstract available


  12. JOHN F, Bosnyak E, Robinette NL, Amit-Yousif AJ, et al
    Multimodal Imaging-defined Subregions in Newly-diagnosed Glioblastoma: Impact on Overall Survival.
    Neuro Oncol. 2018 Oct 22. pii: 5140157. doi: 10.1093.
    PubMed     Text format     Abstract available


  13. DE LEEUW CN, Vogelbaum MA
    Supratotal Resection in Glioma: A Systematic Review.
    Neuro Oncol. 2018 Oct 15. pii: 5131643. doi: 10.1093.
    PubMed     Text format     Abstract available


  14. KORJA M, Raj R, Seppa K, Luostarinen T, et al
    Glioblastoma survival is improving despite increasing incidence rates: a nationwide study between 2000 and 2013 in Finland.
    Neuro Oncol. 2018 Oct 12. pii: 5127281. doi: 10.1093.
    PubMed     Text format     Abstract available


  15. ACHEY RL, Gittleman H, Schroer J, Khanna V, et al
    Non-malignant and malignant meningioma incidence and survival in the elderly from 2005-2015 using the Central Brain Tumor Registry of the United States.
    Neuro Oncol. 2018 Oct 6. pii: 5122860. doi: 10.1093.
    PubMed     Text format     Abstract available


  16. WICK W, Dettmer S, Berberich A, Kessler T, et al
    N2M2 (NOA20) phase I/II trial of molecularly matched targeted therapies plus radiotherapy in patients with newly diagnosed non-MGMT hypermethylated glioblastoma.
    Neuro Oncol. 2018 Oct 1. pii: 5113425. doi: 10.1093.
    PubMed     Text format     Abstract available


  17. BARAJAS RF JR, Hamilton BE, Schwartz D, McConnell HL, et al
    Combined Iron Oxide Nanoparticle Ferumoxytol and Gadolinium Contrast Enhanced MRI Defines Glioblastoma Pseudo-progression.
    Neuro Oncol. 2018 Oct 1. pii: 5113424. doi: 10.1093.
    PubMed     Text format     Abstract available


    September 2018
  18. MORAES FY, Winter J, Atenafu EG, Dasgputa A, et al
    Outcomes following SRS for small- to medium-sized brain metastases are exceptionally dependent upon tumor size and prescribed dose.
    Neuro Oncol. 2018 Sep 28. pii: 5108534. doi: 10.1093.
    PubMed     Text format     Abstract available


  19. ZHANG H, Liao J, Zhang X, Zhao E, et al
    Sex difference of mutation clonality in diffuse glioma evolution.
    Neuro Oncol. 2018 Sep 25. pii: 5106960. doi: 10.1093.
    PubMed     Text format     Abstract available


  20. KORSHUNOV A, Sahm F, Zheludkova O, Golanov A, et al
    DNA-methylation profiling is a method of choice for molecular verification of pediatric WNT activated medulloblastomas.
    Neuro Oncol. 2018 Sep 25. pii: 5106618. doi: 10.1093.
    PubMed     Text format     Abstract available


  21. AJITHKUMAR T, Imbulgoda N, Rees E, Harris F, et al
    Uncommon low-grade brain tumors.
    Neuro Oncol. 2018 Sep 20. pii: 5104003. doi: 10.1093.
    PubMed     Text format     Abstract available


  22. POORE B, Yuan M, Arnold A, Price A, et al
    mTORC1 inhibition in pediatric low-grade glioma depletes glutathione and therapeutically synergizes with carboplatin.
    Neuro Oncol. 2018 Sep 18. pii: 5100756. doi: 10.1093.
    PubMed     Text format     Abstract available


  23. MANSOURI A, Hachem LD, Mansouri S, Nassiri F, et al
    MGMT promoter methylation status testing to guide therapy for glioblastoma: refining the approach based on emerging evidence and current challenges.
    Neuro Oncol. 2018 Sep 5. pii: 5090948. doi: 10.1093.
    PubMed     Text format     Abstract available


  24. YAMASHITA AS, da Costa Rosa M, Borodovsky A, Festuccia WT, et al
    Demethylation and epigenetic modification with 5-Azacytidine reduces IDH1 mutant glioma growth in combination with Temozolomide.
    Neuro Oncol. 2018 Sep 3. pii: 5089721. doi: 10.1093.
    PubMed     Text format     Abstract available


    August 2018
  25. HENCH J, Bihl M, Bratic Hench I, Hoffmann P, et al
    Satisfying your neuro-oncologist: a fast approach to routine molecular glioma diagnostics.
    Neuro Oncol. 2018 Aug 30. pii: 5087930. doi: 10.1093.
    PubMed     Text format    


  26. LIEBERMAN NAP, DeGolier K, Kovar HM, Davis A, et al
    Characterization of the immune microenvironment of diffuse intrinsic pontine glioma: Implications for development of immunotherapy.
    Neuro Oncol. 2018 Aug 28. pii: 5085631. doi: 10.1093.
    PubMed     Text format     Abstract available


  27. JACOBS DI, Fukumura K, Bainbridge MN, Armstrong GN, et al
    Elucidating the molecular pathogenesis of glioma: integrated germline and somatic profiling of a familial glioma case series.
    Neuro Oncol. 2018 Aug 24. pii: 5079134. doi: 10.1093.
    PubMed     Text format     Abstract available


  28. SVENSSON F, Westerman B, Wurdinger T, Bailey D, et al
    GBM Drug Bank-a new resource for glioblastoma drug discovery and informatics research.
    Neuro Oncol. 2018 Aug 20. pii: 5076955. doi: 10.1093.
    PubMed     Text format    


  29. HUANG RY, Bi WL, Weller M, Kaley T, et al
    Proposed Response Assessment and Endpoints for Meningioma Clinical Trials: Report from the Response Assessment in Neuro-Oncology (RANO) Working Group.
    Neuro Oncol. 2018 Aug 18. pii: 5076187. doi: 10.1093.
    PubMed     Text format     Abstract available


  30. OSTROM QT, Coleman W, Huang W, Rubin JB, et al
    Sex-specific gene and pathway modeling of inherited glioma risk.
    Neuro Oncol. 2018 Aug 14. pii: 5073373. doi: 10.1093.
    PubMed     Text format     Abstract available


  31. KIM JY, Park JE, Jo Y, Shim WH, et al
    Incorporating diffusion- and perfusion-weighted MRI into a radiomics model improves diagnostic performance for pseudoprogression in glioblastoma patients.
    Neuro Oncol. 2018 Aug 11. pii: 5069926. doi: 10.1093.
    PubMed     Text format     Abstract available


  32. TEJADA NEYRA MA, Neuberger U, Reinhardt A, Brugnara G, et al
    Voxel-wise radiogenomic mapping of tumor location with key molecular alterations in patients with glioma.
    Neuro Oncol. 2018 Aug 9. pii: 5068679. doi: 10.1093.
    PubMed     Text format     Abstract available


  33. KOK JL, Teepen JC, van Leeuwen FE, Tissing WJE, et al
    Risk of benign meningioma after childhood cancer in the DCOG-LATER cohort: contributions of radiation dose, exposed cranial volume, and age.
    Neuro Oncol. 2018 Aug 7. pii: 5067497. doi: 10.1093.
    PubMed     Text format     Abstract available


  34. HUANG RY, Unadkat P, Linda Bi W, George E, et al
    Response Assessment of Meningioma: 1D, 2D and Volumetric Criteria for Treatment Response and Tumor Progression.
    Neuro Oncol. 2018 Aug 2. pii: 5063817. doi: 10.1093.
    PubMed     Text format     Abstract available


  35. HARTMANN C
    Inclusion bias of patients with genetically different glioblastoma subgroups in clinical trials.
    Neuro Oncol. 2018 Aug 1. pii: 5063295. doi: 10.1093.
    PubMed     Text format    


    July 2018
  36. CHO HJ, Zhao J, Jung SW, Ladewig E, et al
    Distinct genomic profile and specific targeted drug responses in adult cerebellar glioblastoma.
    Neuro Oncol. 2018 Jul 31. pii: 5061885. doi: 10.1093.
    PubMed     Text format     Abstract available


  37. PARK AK, Kim P, Ballester LY, Esquenazi Y, et al
    Subtype-specific signaling pathways and genomic aberrations associated with prognosis of glioblastoma.
    Neuro Oncol. 2018 Jul 25. pii: 5059682. doi: 10.1093.
    PubMed     Text format     Abstract available


  38. KATHAGEN-BUHMANN A, Maire CL, Weller J, Schulte A, et al
    The secreted glycolytic enzyme GPI/AMF stimulates glioblastoma cell migration and invasion in an autocrine fashion but can have antiproliferative effects.
    Neuro Oncol. 2018 Jul 24. pii: 5057755. doi: 10.1093.
    PubMed     Text format     Abstract available


  39. SUH CH, Kim HS, Jung SC, Choi CG, et al
    2-hydroxyglutarate MR Spectroscopy for Prediction of Isocitrate Dehydrogenase Mutant Glioma: A Systemic Review and Meta-analysis using Individual Patient Data.
    Neuro Oncol. 2018 Jul 18. pii: 5055433. doi: 10.1093.
    PubMed     Text format     Abstract available


  40. SPIEGL-KREINECKER S, Lotsch D, Neumayer K, Kastler L, et al
    TERT promoter mutations are associated with poor prognosis and cell immortalization in meningioma.
    Neuro Oncol. 2018 Jul 11. pii: 5052146. doi: 10.1093.
    PubMed     Text format     Abstract available


  41. LASSMAN AB, van den Bent MJ, Gan HK, Reardon DA, et al
    Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro Oncol. 2018 Jul 5. pii: 5049251. doi: 10.1093.
    PubMed     Text format     Abstract available


  42. THEELER BJ
    De novo and secondary anaplastic meningiomas: natural history, prognosis, and the TERT promoter.
    Neuro Oncol. 2018;20:1009-1010.
    PubMed     Text format    


  43. CIMINO PJ, McFerrin L, Wirsching HG, Arora S, et al
    Copy number profiling across glioblastoma populations has implications for clinical trial design.
    Neuro Oncol. 2018 Jul 2. pii: 5047422. doi: 10.1093.
    PubMed     Text format     Abstract available


    June 2018
  44. LEE EQ, McFaline-Figueroa JR, Cloughesy TF, Wen PY, et al
    Is it time to reconsider the role of irinotecan for the treatment of high-grade gliomas?
    Neuro Oncol. 2018 Jun 27. pii: 5046042. doi: 10.1093.
    PubMed     Text format    


  45. MICHAELSEN SR, Staberg M, Pedersen H, Jensen KE, et al
    VEGF-C Sustains VEGFR2 Activation under Bevacizumab Therapy and Promotes Glioblastoma Maintenance.
    Neuro Oncol. 2018 Jun 25. pii: 5043488. doi: 10.1093.
    PubMed     Text format     Abstract available


  46. SA JK, Kim SH, Lee JK, Cho HJ, et al
    Identification of Genomic and Molecular Traits that Present Therapeutic Vulnerability to HGF-targeted therapy in Glioblastoma.
    Neuro Oncol. 2018 Jun 23. pii: 5043207. doi: 10.1093.
    PubMed     Text format     Abstract available


  47. ANDRONESI OC
    Precision oncology in the era of radiogenomics: the case of D-2HG as an imaging biomarker for mutant IDH gliomas.
    Neuro Oncol. 2018;20:865-867.
    PubMed     Text format    


  48. LAL S, Carrera D, Phillips JJ, Weiss WA, et al
    An oncolytic measles virus-sensitive Group 3 medulloblastoma model in immune-competent mice.
    Neuro Oncol. 2018 Jun 14. pii: 5038008. doi: 10.1093.
    PubMed     Text format     Abstract available


  49. BROWN DA, Himes BT, Kerezoudis P, Chilinda-Salter YM, et al
    Insurance Correlates with Improved Access to Care and Outcome Among Glioblastoma Patients.
    Neuro Oncol. 2018 Jun 11. pii: 5035412. doi: 10.1093.
    PubMed     Text format     Abstract available


  50. KUNZ M, Albert NL, Unterrainer M, la Fougere C, et al
    Dynamic 18F-FET PET is a powerful imaging biomarker in gadolinium-negative gliomas.
    Neuro Oncol. 2018 Jun 9. pii: 5035376. doi: 10.1093.
    PubMed     Text format     Abstract available


  51. FALK DELGADO A, De Luca F, van Westen D, Falk Delgado A, et al
    Arterial Spin Labeling MR imaging for differentiation between high and low grade glioma - a meta-analysis.
    Neuro Oncol. 2018 Jun 2. pii: 5032325. doi: 10.1093.
    PubMed     Text format     Abstract available


  52. LOMBARDI G, Della Puppa A, Gardiman MP, Rossi S, et al
    Discordance of IDH mutational status between lesions in an adult patient with multifocal glioma.
    Neuro Oncol. 2018 Jun 2. pii: 5032324. doi: 10.1093.
    PubMed     Text format    


    May 2018
  53. ZHANG L, He L, Lugano R, Roodakker K, et al
    IDH-mutation Status is Associated with Distinct Vascular Gene Expression Signatures in Lower Grade Gliomas.
    Neuro Oncol. 2018 May 29. pii: 5018656. doi: 10.1093.
    PubMed     Text format     Abstract available


  54. DASGUPTA A, Gupta T, Pungavkar S, Shirsat N, et al
    Nomograms based on Pre-operative Multi-parametric Magnetic Resonance Imaging for Prediction of Molecular Subgrouping in Medulloblastoma: Results from a Radiogenomics Study of 111 Patients.
    Neuro Oncol. 2018 May 29. pii: 5018966. doi: 10.1093.
    PubMed     Text format     Abstract available


  55. JOSEPH SK, Samaha H, Bielamowicz K, Ahmed N, et al
    Invited Response to the Comment by Caruso and Heimberger on "Trivalent CAR T cells overcome interpatient antigenic variability in glioblastoma" by Bielamowicz et al.
    Neuro Oncol. 2018 May 19. pii: 4999739. doi: 10.1093.
    PubMed     Text format    


  56. BROWN NF, Williams M, Arkenau HT, Fleming RA, et al
    A Study of the Focal Adhesion Kinase Inhibitor GSK2256098 in Patients with Recurrent Glioblastoma with Evaluation of Tumor Penetration of [11C]GSK2256098.
    Neuro Oncol. 2018 May 17. pii: 4998845. doi: 10.1093.
    PubMed     Text format     Abstract available


  57. GILLESPIE S, Monje M
    An Active Role for Neurons in Glioma Progression: Making Sense of Scherer's Structures.
    Neuro Oncol. 2018 May 17. pii: 4998849. doi: 10.1093.
    PubMed     Text format     Abstract available


  58. GEURTS M, van den Bent MJ
    Timing of radiotherapy in newly diagnosed glioblastoma: no need to rush?
    Neuro Oncol. 2018 May 15. pii: 4996074. doi: 10.1093.
    PubMed     Text format    


  59. VAN DEN BOSSCHE WBL, Kleijn A, Teunissen CE, Voerman JSA, et al
    Oncolytic virotherapy in glioblastoma patients induces a tumor macrophage phenotypic shift leading to an altered glioblastoma microenvironment.
    Neuro Oncol. 2018 May 15. pii: 4996453. doi: 10.1093.
    PubMed     Text format     Abstract available


  60. CLAUS EB, Cornish AJ, Broderick P, Schildkraut JM, et al
    Genome-wide association analysis identifies a meningioma risk locus at 11p15.5.
    Neuro Oncol. 2018 May 12. pii: 4995586. doi: 10.1093.
    PubMed     Text format     Abstract available


  61. CLOUGHESY TF, Landolfi J, Vogelbaum MA, Ostertag D, et al
    Durable Complete Responses in Some Recurrent High Grade Glioma Patients Treated with Toca 511 & Toca FC.
    Neuro Oncol. 2018 May 12. pii: 4995454. doi: 10.1093.
    PubMed     Text format     Abstract available


  62. PUDELKO L, Edwards S, Balan M, Nyqvist D, et al
    An orthotopic glioblastoma animal model suitable for high-throughput screenings.
    Neuro Oncol. 2018 May 10. pii: 4994699. doi: 10.1093.
    PubMed     Text format     Abstract available


  63. ZACHARIAH M, Oliveira-Costa JP, Carter B, Stott SL, et al
    Blood-Based Biomarkers for the Diagnosis and Monitoring of Gliomas.
    Neuro Oncol. 2018 May 9. pii: 4994194. doi: 10.1093.
    PubMed     Text format    


  64. GUPTA N, Goumnerova LC, Manley P, Chi SN, et al
    Prospective Feasibility and Safety Assessment of Surgical Biopsy for Patients with Newly Diagnosed Diffuse Intrinsic Pontine Glioma.
    Neuro Oncol. 2018 May 5. pii: 4993208. doi: 10.1093.
    PubMed     Text format     Abstract available


  65. KARACHI A, Dastmalchi F, Mitchell D, Rahman M, et al
    Temozolomide for Immunomodulation in the Treatment of Glioblastoma.
    Neuro Oncol. 2018 May 4. pii: 4992672. doi: 10.1093.
    PubMed     Text format     Abstract available


  66. PAECH D, Windschuh J, Oberhollenzer J, Dreher C, et al
    Assessing the predictability of IDH mutation and MGMT methylation status in glioma patients using relaxation-compensated multi-pool CEST MRI at 7.0 Tesla.
    Neuro Oncol. 2018 May 4. pii: 4992691. doi: 10.1093.
    PubMed     Text format     Abstract available


    April 2018
  67. STADLBAUER A, Zimmermann M, Doerfler A, Oberndorfer S, et al
    Intratumoral Heterogeneity of Oxygen Metabolism and Neovascularization Uncovers Two Survival Relevant Subgroups of IDH1 Wild-type Glioblastoma.
    Neuro Oncol. 2018 Apr 28. pii: 4989834. doi: 10.1093.
    PubMed     Text format     Abstract available


  68. ELLINGSON BM, Abrey LE, Garcia J, Chinot O, et al
    Post-chemoradiation volumetric response predicts survival in newly diagnosed glioblastoma treated with radiation, temozolomide and bevacizumab or placebo.
    Neuro Oncol. 2018 Apr 20. pii: 4979515. doi: 10.1093.
    PubMed     Text format     Abstract available


  69. HERSH DS, Harder BG, Roos A, Peng S, et al
    The TNF Receptor Family Member Fn14 is Highly Expressed in Recurrent Glioblastoma (GBM) and in GBM Patient-Derived Xenografts With Acquired Temozolomide Resistance.
    Neuro Oncol. 2018 Apr 20. pii: 4979510. doi: 10.1093.
    PubMed     Text format     Abstract available


  70. DU Z, Brewster R, Merrill PH, Chmielecki J, et al
    Meningioma transcription factors link cell lineage with systemic metabolic cues.
    Neuro Oncol. 2018 Apr 12. pii: 4969420. doi: 10.1093.
    PubMed     Text format     Abstract available


  71. KOGA T, Li B, Figueroa JM, Ren B, et al
    Mapping of genomic EGFRvIII deletions in glioblastoma: insight into rearrangement mechanisms and biomarker development.
    Neuro Oncol. 2018 Apr 12. pii: 4969527. doi: 10.1093.
    PubMed     Text format     Abstract available


  72. CARUSO H, Heimberger AB
    Comment on "Trivalent CAR T cells overcome interpatient antigenic variability in glioblastoma".
    Neuro Oncol. 2018 Apr 10. pii: 4965825. doi: 10.1093.
    PubMed     Text format    


  73. LINNINGER A, Hartung GA, Liu BP, Mirkov S, et al
    Modeling the diffusion of D-2-hydroxyglutarate from IDH1 mutant gliomas in the central nervous system.
    Neuro Oncol. 2018 Apr 5. pii: 4962158. doi: 10.1093.
    PubMed     Text format     Abstract available


  74. ELLINGSON BM, Abrey LE, Nelson SJ, Kaufmann TJ, et al
    Validation of post-operative residual contrast enhancing tumor volume as an independent prognostic factor for overall survival in newly diagnosed glioblastoma.
    Neuro Oncol. 2018 Apr 5. pii: 4962189. doi: 10.1093.
    PubMed     Text format     Abstract available


  75. ELLINGSON BM, Aftab DT, Schwab GM, Hessel C, et al
    Volumetric response quantified using T1 subtraction predicts long-term survival benefit from cabozantinib monotherapy in recurrent glioblastoma.
    Neuro Oncol. 2018 Apr 5. pii: 4962211. doi: 10.1093.
    PubMed     Text format     Abstract available


  76. ALEXANDER BM, Cloughesy TF
    Platform trials arrive on time for glioblastoma.
    Neuro Oncol. 2018 Apr 2. pii: 4958219. doi: 10.1093.
    PubMed     Text format    


    March 2018
  77. AKBARI H, Bakas S, Pisapia JM, Nasrallah MP, et al
    In vivo evaluation of EGFRvIII mutation in primary glioblastoma patients via complex multiparametric MRI signature.
    Neuro Oncol. 2018 Mar 30. pii: 4956862. doi: 10.1093.
    PubMed     Text format     Abstract available


  78. BABAK S, Mason WP
    mTOR inhibition in glioblastoma: requiem for a dream?
    Neuro Oncol. 2018 Mar 28. pii: 4955983. doi: 10.1093.
    PubMed     Text format    


  79. NASSIRI F, Aldape K, Zadeh G
    The multiforme of glioblastoma.
    Neuro Oncol. 2018;20:437-438.
    PubMed     Text format    


  80. BOXERMAN JL, Zhang Z, Safriel Y, Rogg JM, et al
    Prognostic Value of Contrast Enhancement and FLAIR for Survival in Newly Diagnosed Glioblastoma Treated With and Without Bevacizumab: Results from ACRIN 6686.
    Neuro Oncol. 2018 Mar 26. pii: 4953723. doi: 10.1093.
    PubMed     Text format     Abstract available


  81. BROEN MPG, Smits M, Wijnenga MMJ, Dubbink HJ, et al
    The T2-FLAIR Mismatch Sign as an Imaging Marker for Non-Enhancing IDH-mutant, 1p/19q-intact Lower Grade Glioma: A Validation Study.
    Neuro Oncol. 2018 Mar 26. pii: 4953716. doi: 10.1093.
    PubMed     Text format     Abstract available


  82. ANGUS SP, Oblinger JL, Stuhlmiller TJ, DeSouza PA, et al
    EPH receptor signaling as a novel therapeutic target in NF2-deficient meningioma.
    Neuro Oncol. 2018 Mar 21. pii: 4947870. doi: 10.1093.
    PubMed     Text format     Abstract available


  83. SAADEH FS, Melamed EF, Rea ND, Krieger MD, et al
    Seizure outcomes of supratentorial brain tumor resection in pediatric patients.
    Neuro Oncol. 2018 Mar 20. pii: 4944459. doi: 10.1093.
    PubMed     Text format     Abstract available


  84. PEDROSA R, Mustafa DA, Soffietti R, Kros JM, et al
    Breast cancer brain metastasis: molecular mechanisms and directions for treatment.
    Neuro Oncol. 2018 Mar 16. pii: 4939604. doi: 10.1093.
    PubMed     Text format     Abstract available


  85. HE J, Zhao Y, Zhao E, Wang X, et al
    Cancer-testis Specific Gene OIP5: A Downstream Gene of E2F1 that Promotes Tumorigenesis and Metastasis in Glioblastoma by Stabilizing E2F1 Signalling.
    Neuro Oncol. 2018 Mar 14. pii: 4934327. doi: 10.1093.
    PubMed     Text format     Abstract available


  86. APPAY R, Tabouret E, Macagno N, Touat M, et al
    IDH2 mutations are commonly associated with 1p/19q codeletion in diffuse adult gliomas.
    Neuro Oncol. 2018 Mar 7. pii: 4924365. doi: 10.1093.
    PubMed     Text format    


  87. VANDERBEEK AM, Rahman R, Fell G, Ventz S, et al
    The clinical trials landscape for glioblastoma: is it adequate to develop new treatments?
    Neuro Oncol. 2018 Mar 6. pii: 4922286. doi: 10.1093.
    PubMed     Text format     Abstract available


  88. COY S, Rashid R, Lin JR, Du Z, et al
    Multiplexed Immunofluorescence Reveals Potential PD-1/PD-L1 Pathway Vulnerabilities in Craniopharyngioma.
    Neuro Oncol. 2018 Mar 2. pii: 4917565. doi: 10.1093.
    PubMed     Text format     Abstract available


  89. BAGLEY SJ, Desai AS, Linette GP, June CH, et al
    CAR T Cell Therapy for Glioblastoma: Recent Clinical Advances and Future Challenges.
    Neuro Oncol. 2018 Mar 2. pii: 4917531. doi: 10.1093.
    PubMed     Text format     Abstract available


    February 2018
  90. PARK JW, Wollmann G, Urbiola C, Fogli B, et al
    Sprouty2 enhances the tumorigenic potential of glioblastoma cells.
    Neuro Oncol. 2018 Feb 23. pii: 4904223. doi: 10.1093.
    PubMed     Text format     Abstract available


  91. OSTROM QT, Rubin JB, Lathia JD, Berens ME, et al
    Females have the survival advantage in glioblastoma.
    Neuro Oncol. 2018 Feb 21. pii: 4883496. doi: 10.1093.
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    Short delay in initiation of radiotherapy for patients with glioblastoma- effect of concurrent chemotherapy: a secondary analysis from the NRG Oncology/Radiation Therapy Oncology Group (RTOG) database.
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  93. BASKARAN S, Mayrhofer M, Kultima HG, Bergstrom T, et al
    Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages.
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    Temozolomide-associated Hypermutation in Gliomas.
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    Diagnostic Accuracy of 2-Hydroxyglutarate Magnetic Resonance Spectroscopy in Newly-Diagnosed Brain Mass and Suspected Recurrent Gliomas.
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  96. ABOUNADER R
    A new practical and versatile mouse model of proneural glioblastoma.
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  97. ALDAPE K, Amin SB, Ashley DM, Barnholtz-Sloan JS, et al
    Glioma Through the Looking GLASS: Molecular Evolution of Diffuse Gliomas and the Glioma Longitudinal AnalySiS Consortium.
    Neuro Oncol. 2018 Feb 8. pii: 4843984. doi: 10.1093.
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  98. LIAO P, Ostrom QT, Stetson L, Barnholtz-Sloan JS, et al
    Models of Epigenetic Age Capture Patterns of DNA Methylation in Glioma Associated with Molecular Subtype, Survival, and Recurrence.
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  99. BRENNER A, Zuniga R, Sun JD, Floyd J, et al
    Hypoxia Activated Evofosfamide for Treatment of Recurrent Bevacizumab-Refractory Glioblastoma: A phase I surgical study.
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  100. NHAT TRAN A, Walker K, Harrison DG, Chen W, et al
    Reactive Species Balance via GTP Cyclohydrolase I Regulates Glioblastoma Growth and Tumor Initiating Cell Maintenance.
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  101. LOUVRIER C, Pasmant E, Briand-Suleau A, Cohen J, et al
    Targeted next-generation sequencing for differential diagnosis of neurofibromatosis type 2, schwannomatosis, and meningiomatosis.
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    SYK Inhibition Blocks Proliferation and Migration of Glioma Cells, and Modifies the Tumor Microenvironment.
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    The aberrant splicing of BAF45d links splicing regulation and transcription in glioblastoma.
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  104. AUDIA A, Bhat KP
    Ritanserin, a novel agent targeting the mesenchymal subtype of glioblastomas.
    Neuro Oncol. 2018;20:151-152.
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  105. RUBIN JB, Finlay JL
    Pediatric low-grade gliomas: a brave new world.
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  106. WARREN KE, Vezina G, Poussaint TY, Warmuth-Metz M, et al
    Response to Harreld re: "Response assessment in medulloblastoma and leptomeningeal seeding tumors: recommendations from the Response Assessment in Pediatric Neuro-Oncology Committee".
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  107. HARRELD JH
    Comment on "Response assessment in medulloblastoma and leptomeningeal seeding tumors: recommendations from the Response Assessment in Pediatric Neuro-Oncology Committee".
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  108. PRUST ML, Jafari-Khouzani K, Kalpathy-Cramer J, Polaskova P, et al
    Standard chemoradiation in combination with VEGF targeted therapy for glioblastoma results in progressive gray and white matter volume loss.
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  109. CHIN AL, Moding EJ, Donaldson SS, Gibbs IC, et al
    Survival Impact of Postoperative Radiotherapy Timing in Pediatric and Adolescent Medulloblastoma.
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  110. RUDA R, Soffietti R
    Extent of surgery in low-grade gliomas: an old question in a new context.
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    December 2017
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    Regulation of bioenergetics through dual inhibition of aldehyde dehydrogenase and mitochondrial complex I suppresses glioblastoma tumorspheres.
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  112. MAHLOKOZERA T, Vellimana AK, Li T, Mao DD, et al
    Biological and therapeutic implications of multisector sequencing in newly diagnosed glioblastomas.
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  113. CALMON R, Puget S, Varlet P, Dangouloff-Ros V, et al
    Cerebral blood flow changes after radiation therapy identifies pseudo-progression in diffuse intrinsic pontine gliomas.
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  114. IUS T, Ciani Y, Ruaro ME, Isola M, et al
    A NF-kappaB signature predicts low-grade glioma prognosis: a precision medicine approach based on patient-derived stem cells.
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  115. PEYRE M, Gauchotte G, Giry M, Froehlich S, et al
    De novo and secondary anaplastic meningiomas: a study of clinical and histomolecular prognostic factors.
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    November 2017
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    Germline SUFU mutation carriers and medulloblastoma: clinical characteristics, cancer risk and prognosis.
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  117. PFAFF E, Kessler T, Balasubramanian GP, Berberich A, et al
    Feasibility of real-time molecular profiling for patients with newly diagnosed glioblastoma without MGMT promoter-hypermethylation - the NCT Neuro Master Match (N2M2) pilot study.
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  118. DOVER LL, Dulaney CR, Williams CP, Fiveash JB, et al
    Hospice care, cancer-directed therapy, and Medicare expenditures among older patients dying with malignant brain tumors.
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  119. ABDELBAKI MS, Boue DR, Finlay JL, Kieran MW, et al
    Desmoplastic Nodular Medulloblastoma in Young Children: A Management Dilemma.
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  120. NASSIRI F, Zadeh G, Aldape K
    IDH mutation testing in gliomas-where do we draw the line?
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  121. LAKS DR, Oses-Prieto JA, Alvarado AG, Nakashima J, et al
    A Molecular Cascade Modulates MAP1B and Confers Resistance to mTOR Inhibition in Human Glioblastoma.
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  122. SCHAFER N, Proescholdt M, Steinbach JP, Weyerbrock A, et al
    Quality of life in the GLARIUS trial randomizing bevacizumab/irinotecan versus temozolomide in newly diagnosed, MGMT-nonmethylated glioblastoma.
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  123. GONDI V, Mehta MP
    Control versus cognition: the changing paradigm of adjuvant therapy for resected brain metastasis.
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  124. CHINNAIYAN P, Won M, Wen PY, Rojiani AM, et al
    A randomized phase II study of everolimus in combination with chemoradiation in newly diagnosed glioblastoma: Results of NRG Oncology RTOG 0913.
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  125. CARAGHER SP, Hall RR 3rd, Ahsan R, Ahmed AU, et al
    Monoamines in Glioblastoma: complex biology with therapeutic potential.
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  126. WANG J, Yang ZY, Guo YF, Kuang JY, et al
    Targeting different domains of gap junction protein to control malignant glioma.
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    PRMT5 as a druggable target for glioblastoma therapy.
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  128. TENG J, Hejazi S, Hiddingh L, Carvalho L, et al
    Recycling drug screen repurposes hydroxyurea as a sensitizer of glioblastomas to temozolomide targeting de novo DNA synthesis, irrespective of molecular subtype.
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    October 2017
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    Synergy of vaccination and agonist OX40 treatment-toward a mechanism-driven combination of glioma immunotherapy.
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  130. OMURO A, Vlahovic G, Lim M, Sahebjam S, et al
    Nivolumab with or without ipilimumab in patients with recurrent glioblastoma: results from exploratory phase 1 cohorts of CheckMate 143.
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  131. GAN HK, Reardon DA, Lassman AB, Merrell R, et al
    Safety, Pharmacokinetics and Antitumor Response of Depatuxizumab Mafodotin as Monotherapy or in Combination with Temozolomide in Patients with Glioblastoma.
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  132. HAYES J, Yu Y, Jalbert LE, Mazor T, et al
    Genomic analysis of the origins and evolution of multicentric diffuse lower-grade gliomas.
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    EGFRvIII vaccine in glioblastoma-InACT-IVe or not ReACTive enough?
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  134. UNTERRAINER M, Niyazi M, Ruf V, Bartenstein P, et al
    The endothelial prostate-specific membrane antigen is highly expressed in gliosarcoma and visualized by [68Ga]-PSMA-11 PET: a theranostic outlook for brain tumor patients?
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    Hospice Utilization in Patients with Malignant Gliomas.
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  136. ELLINGSON BM, Wen PY, Cloughesy TF
    Evidence and Context of Use for Contrast Enhancement as a Surrogate of Disease Burden and Treatment Response in Malignant Glioma.
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  137. ESKILSSON E, Rosland GV, Solecki G, Wang Q, et al
    EGFR heterogeneity and implications for therapeutic intervention in glioblastoma.
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  138. RUIZ VY, Praska CE, Armstrong G, Kollmeyer TM, et al
    Molecular Subtyping of Tumors from Patients with Familial Glioma.
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  139. CLOUGHESY TF, Drappatz J, de Groot J, Prados MD, et al
    Phase II study of cabozantinib in patients with progressive glioblastoma: subset analysis of patients with prior antiangiogenic therapy.
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  140. JOHN-PAUL K, Bartels U
    Intracystic interferon-alpha in pediatric craniopharyngioma patients-reply.
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  141. PENAS-PRADO M, de Groot J
    CATNON interim results: another triumph of upfront chemotherapy in glioma.
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  142. CAVALHEIRO S
    Intracystic interferon-alpha in pediatric craniopharyngioma patients.
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  143. LOU E
    Can you hear them now? Tumor microtubes form cellular communication networks that protect gliomas from surgical lesions and chemotherapy treatments.
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    September 2017
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    Radiomic subtyping improves disease stratification beyond key molecular, clinical and standard imaging characteristics in patients with glioblastoma.
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  145. MALTA TM, de Souza CF, Sabedot TS, Silva TC, et al
    Glioma CpG Island Methylator Phenotype (G-CIMP): Biological and Clinical Implications.
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  146. KAUR S, Ramdzan ZM, Guiot MC, Li L, et al
    CUX1 Stimulates APE1 Enzymatic Activity and Increases the Resistance of Glioblastoma Cells to the Mono-Alkylating Agent, Temozolomide.
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  147. SAHM F, Wick A
    ID(H)entifying checkpoint inhibitor candidates among diffuse glioma.
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  148. BIELAMOWICZ K, Fousek K, Byrd TT, Samaha H, et al
    Trivalent CAR T-cells Overcome Interpatient Antigenic Variability in Glioblastoma.
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    Challenges of developing small molecule kinase inhibitors for brain tumors and the need for emphasis on free drug levels.
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    PIK3CB/p110beta is a Selective Survival Factor for Glioblastoma.
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    Visual and semiquantitative 11C-methionine PET: An independent prognostic factor for survival of newly diagnosed and treatment naive gliomas.
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    Attention-mediated neurocognitive profiles in survivors of pediatric brain tumors: Comparison to children with neurodevelopmental ADHD.
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    Is the blood-brain barrier really disrupted in all glioblastomas? - A critical assessment of existing clinical data.
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  154. WIJNENGA MMJ, French PJ, Dubbink HJ, Dinjens WNM, et al
    The impact of surgery in molecularly defined low-grade glioma: an integrated clinical, radiological and molecular analysis.
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    Metabolic heterogeneity and plasticity of glioma stem cells in a mouse glioblastoma model.
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  156. BALASUBRAMANIYAN V, Bhat KP
    Targeting MIR155HG in glioma: a novel approach.
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  157. COONEY T, Lane A, Bartels U, Bouffet E, et al
    Contemporary survival endpoints: an International Diffuse Intrinsic Pontine Glioma Registry study.
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  158. SCHNEIDER M, Reitter EM, Kastner MT, Thannesberger J, et al
    Absence of CMV viremia in high-grade glioma patients under low dosage glucocorticoid treatment.
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  159. GOERIG NL, Frey B, Uberla K, Gaipl U, et al
    A clinician's plea to test glioma patients for CMV.
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  160. NOWOSIELSKI M, Ellingson BM, Chinot OL, Garcia J, et al
    Radiologic progression of glioblastoma under therapy - an exploratory analysis of AVAglio.
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    August 2017
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    Long-term Exposure to Ambient Air Pollution and Incidence of Brain Tumor: the European Study of Cohorts for Air Pollution Effects (ESCAPE).
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  162. SZULZEWSKY F, Schwendinger N, Guneykaya D, Cimino PJ, et al
    Loss of host-derived osteopontin creates a glioblastoma-promoting microenvironment.
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  163. TAUNK NK, Oh JH, Shukla-Dave A, Beal K, et al
    Early Post-treatment Assessment of MRI Perfusion Biomarkers Can Predict Long-term Response of Lung Cancer Brain Metastases to Stereotactic Radiosurgery.
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  164. KESSLER T, Sahm F, Sadik A, Stichel D, et al
    Molecular differences in IDH wildtype glioblastoma according to MGMT promoter methylation.
    Neuro Oncol. 2017 Aug 24. doi: 10.1093.
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  165. KHAGI S, Miller CR
    Putting "multiforme" back into glioblastoma: intratumoral transcriptome heterogeneity is a consequence of its complex morphology.
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  166. GALANIS E, Anderson SK, Miller CR, Sarkaria JN, et al
    Phase I/II Trial of Vorinostat Combined with Temozolomide and Radiation Therapy for Newly Diagnosed Glioblastoma: Final Results of Alliance N0874/ABTC 02.
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  167. DAGMAR D, Proescholdt M, Reinert C, Pietsch T, et al
    Multicenter pilot study of radio-chemotherapy as first-line treatment for adults with medulloblastoma (NOA-07).
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  168. WEN PY, Drappatz J, de Groot J, Prados MD, et al
    Phase II study of cabozantinib in patients with progressive glioblastoma: subset analysis of patients naive to antiangiogenic therapy.
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  169. LANG FM, Hossain A, Gumin J, Momin EN, et al
    Mesenchymal Stem Cells as Natural Bio-Factories for Exosomes Carrying miR-124a in the Treatment of Gliomas.
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  170. KARREMANN M, Gielen GH, Hoffmann M, Wiese M, et al
    Diffuse high-grade gliomas with H3 K27M mutations carry a dismal prognosis independent of tumor location.
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  171. JONES DTW, Kieran MW, Bouffet E, Alexandrescu S, et al
    Pediatric Low-Grade Gliomas: Next Biologically Driven Steps.
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  172. GROSSMAN SA, Kleinberg L
    A search for the "Goldilocks zone" with regard to the optimal duration of adjuvant temozolomide in patients with glioblastoma.
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    July 2017
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    Inability of positive phase II clinical trials of investigational treatments to subsequently predict positive phase III clinical trials in glioblastoma.
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    Divergent evolution of temozolomide resistance in glioblastoma stem cells is reflected in extracellular vesicles and coupled with radiosensitization.
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    A Proposed Framework of Supportive and Palliative Care for people with High Grade Glioma.
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  176. BHERE D, Tamura K, Wakimoto H, Choi SH, et al
    microRNA-7 upregulates death receptor 5 and primes resistant brain tumors to caspase-mediated apoptosis.
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    Selective BCL-XL inhibition promotes apoptosis in combination with MLN8237 in medulloblastoma and pediatric glioblastoma cells.
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    Posterior fossa syndrome and long-term neuropsychological outcomes among children treated for medulloblastoma on a multi-institutional, prospective study.
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    Prognostic relevance of genetic alterations in diffuse lower-grade gliomas.
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    Glioblastoma in the elderly: solid conclusions built on shifting sand?
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    Clinical characteristics associated with postoperative seizure control in adult low-grade gliomas: a systematic review and meta-analysis.
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  183. COULDWELL WT, Cannon-Albright LA
    A description of familial clustering of meningiomas in the Utah population.
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  184. WU S, Wang S, Gao F, Li L, et al
    Activation of WEE1 confers resistance to PI3K inhibition in glioblastoma.
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  185. JAHAN N, Talat H, Curry WT
    Agonist OX40 immunotherapy improves survival in glioma-bearing mice and is complementary with vaccination with irradiated GM-CSF-expressing tumor cells.
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  186. RAHME GJ, Luikart BW, Cheng C, Israel MA, et al
    A recombinant lentiviral PDGF-driven mouse model of proneural glioblastoma.
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    Dissecting human gliomas by single-cell RNA sequencing.
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  188. OKADA H, Thorne SH
    Is the immune response a friend or foe for viral therapy of glioma?
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  189. ZHANG Z, Chan AK, Ding X, Li Y, et al
    Glioma groups classified by IDH and TERT promoter mutations remain stable among primary and recurrent gliomas.
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    June 2017
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    Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha.
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    Cost-effectiveness of IDH testing in diffuse gliomas according to the 2016 WHO classification of tumors of the central nervous system recommendations.
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  196. GALLDIKS N, Albert NL, Sommerauer M, Grosu AL, et al
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  199. MORROW AM, Morgan RM, Villano JL
    Seizure control as a new metric in assessing efficacy of tumor treatment in low-grade glioma trials-impact of psychogenic non-epileptic seizures.
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  200. WANG X, Holgado BL, Ramaswamy V, Mack S, et al
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  206. GLASS JO, Ogg RJ, Hyun JW, Harreld JH, et al
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    Lessons learned from diffuse intrinsic pontine glioma: how a terrible disease forced us to think better.
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  210. JACKSON S, ElAli A, Virgintino D, Gilbert MR, et al
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  215. GROSSMANN P, Narayan V, Chang K, Rahman R, et al
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  240. WEN PY, Jiang T, Schiff D
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  253. FOULADI M, Pfister SM
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  262. JEON MS, Dhillon HM, Agar MR
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