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Neoplasms of the CNS

Free Subscription Articles published in Proc Natl Acad Sci U S A Retrieve available abstracts of 47 articles: HTML format

Single Articles

June 2026
1. ZHENG D, Li F, Zhang Z, Dong Y, et al
   TFPI2 promotes NK cell-mediated glioblastoma killing through adhesion and checkpoint control.
   Proc Natl Acad Sci U S A. 2026;123:e2529973123.
   PubMed     Abstract available
   
   
   
2. KIELISZEK AM, Apel E, Zheng S, Piotrowski M, et al
   Selectively targeting inosine monophosphate dehydrogenase-2 impairs brain metastatic potential while preserving immune cell function.
   Proc Natl Acad Sci U S A. 2026;123:e2603440123.
   PubMed     Abstract available
   
   
   
3. LOZZI B, Gatesman TA, Dasgupta P, Sardar D, et al
   Hp1bp3 loss links chromatin reorganization to metabolic vulnerability in glioma.
   Proc Natl Acad Sci U S A. 2026;123:e2601061123.
   PubMed     Abstract available
   
   
   March 2026
4. POLARA R, Gliddon BL, Ganesan R, Davies LT, et al
   CD47 stabilizes ROBO2 to regulate glioblastoma progression by preventing ITCH-mediated ubiquitination.
   Proc Natl Acad Sci U S A. 2026;123:e2602460123.
   PubMed     Abstract available
   
   
   
5. CHEN X, Zhong X, Yue W, Wang B, et al
   A transcription regulator atlas identifies TOX3 as an Atoh1 coactivator in cerebellar development and tumorigenesis.
   Proc Natl Acad Sci U S A. 2026;123:e2527163123.
   PubMed     Abstract available
   
   
   
6. BILLINGHAM LK, DeLay SL, Eshac Y, Chia TY, et al
   Microglial fructose metabolism is essential for glioblastoma growth.
   Proc Natl Acad Sci U S A. 2026;123:e2521256123.
   PubMed     Abstract available
   
   
   
7. FU Z, Zhao X, Zhang Q, Han M, et al
   Synthetic SIGLEC9-based chimeric switch receptor augments the efficacy of CAR macrophages against glioblastoma.
   Proc Natl Acad Sci U S A. 2026;123:e2519819123.
   PubMed     Abstract available
   
   
   January 2026
8. ZARODNIUK M, Wenninger A, Najera J, Lee J, et al
   Mechanical compression induces neuronal apoptosis, reduces synaptic activity, and promotes glial neuroinflammation in mice and humans.
   Proc Natl Acad Sci U S A. 2026;123:e2513172122.
   PubMed     Abstract available
   
   
   
9. KAANOGLU H, Akyel YK, Adefolaju A, Valdivia A, et al
   Combinatorial treatment of glioblastoma with temozolomide (TMZ) plus 5-ethynyl-2'-deoxyuridine (EdU).
   Proc Natl Acad Sci U S A. 2026;123:e2532187123.
   PubMed     Abstract available
   
   
   November 2025
10. 
    Correction for Goyette et al., Cancer-stromal cell interactions in breast cancer brain metastases induce glycocalyx-mediated resistance to HER2-targeting therapies.
    Proc Natl Acad Sci U S A. 2025;122:e2530590122.
    PubMed    
    
    
    
11. MAHAJAN AS, Dussold C, Kim S, Jarvis R, et al
    cGAS-agonistic spherical nucleic acids reprogram the glioblastoma immune microenvironment and promote antitumor immunity.
    Proc Natl Acad Sci U S A. 2025;122:e2409557122.
    PubMed     Abstract available
    
    
    
12. MELSSEN M, Dimberg A
    Keeping Wnt in check for efficient checkpoint blockade in glioblastoma.
    Proc Natl Acad Sci U S A. 2025;122:e2523639122.
    PubMed    
    
    
    September 2025
13. KRISHNAN S, Lee S, Amoozgar Z, Subudhi S, et al
    Wnt inhibition alleviates resistance to anti-PD1 therapy and improves antitumor immunity in glioblastoma.
    Proc Natl Acad Sci U S A. 2025;122:e2414941122.
    PubMed     Abstract available
    
    
    
14. KEAHI DL, Sanders MA, Paul MR, Webster ALH, et al
    G-quadruplexes as a source of vulnerability in BRCA2-deficient granule cell progenitors and medulloblastoma.
    Proc Natl Acad Sci U S A. 2025;122:e2503872122.
    PubMed     Abstract available
    
    
    August 2025
15. KHAN F, Liu Y, Whitfield D, Pang L, et al
    Macrophage TBK1 signaling drives the development and outgrowth of breast cancer brain metastasis.
    Proc Natl Acad Sci U S A. 2025;122:e2420793122.
    PubMed     Abstract available
    
    
    July 2025
16. ZHOU L, Song Q, Zhang X, Cao M, et al
    In vivo generation of CAR macrophages via the enucleated mesenchymal stem cell delivery system for glioblastoma therapy.
    Proc Natl Acad Sci U S A. 2025;122:e2426724122.
    PubMed     Abstract available
    
    
    
17. ZHU Z, Wang H, Li T, Huang TM, et al
    OMT and tensor SVD-based deep learning model for segmentation and predicting genetic markers of glioma: A multicenter study.
    Proc Natl Acad Sci U S A. 2025;122:e2500004122.
    PubMed     Abstract available
    
    
    June 2025
18. 
    Correction for Feng et al., Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis.
    Proc Natl Acad Sci U S A. 2025;122:e2511499122.
    PubMed    
    
    
    May 2025
19. 
    Correction to Supporting Information for Jensen et al., Bcl2L13 is a ceramide synthase inhibitor in glioblastoma.
    Proc Natl Acad Sci U S A. 2025;122:e2507673122.
    PubMed    
    
    
    
20. ZHANG L, Yang J, Zhou Z, Ren Y, et al
    A zinc transporter drives glioblastoma progression via extracellular vesicles-reprogrammed microglial plasticity.
    Proc Natl Acad Sci U S A. 2025;122:e2427073122.
    PubMed     Abstract available
    
    
    April 2025
21. 
    Correction for He et al., Radiation-induced cellular plasticity primes glioblastoma for forskolin-mediated differentiation.
    Proc Natl Acad Sci U S A. 2025;122:e2506044122.
    PubMed    
    
    
    March 2025
22. 
    Correction for Xu et al., BCL6 promotes glioma and serves as a therapeutic target.
    Proc Natl Acad Sci U S A. 2025;122:e2504152122.
    PubMed    
    
    
    
23. DI CARO V, Cesari P, Sala F, Cattaneo L, et al
    The neural bases of the reach-grasp movement in humans: Quantitative evidence from brain lesions.
    Proc Natl Acad Sci U S A. 2025;122:e2419801122.
    PubMed     Abstract available
    
    
    
24. HE L, Azizad D, Bhat K, Ioannidis A, et al
    Radiation-induced cellular plasticity primes glioblastoma for forskolin-mediated differentiation.
    Proc Natl Acad Sci U S A. 2025;122:e2415557122.
    PubMed     Abstract available
    
    
    February 2025
25. LI J, Shih LK, Markwell SM, Olson CL, et al
    A clinically relevant model and method to study necrosis as a driving force in glioma restructuring and progression.
    Proc Natl Acad Sci U S A. 2025;122:e2416024122.
    PubMed     Abstract available
    
    
    January 2025
26. REN J, Amoozgar Z, Uccello TP, Lei PJ, et al
    Targeting EPHB2/ABL1 restores antitumor immunity in preclinical models of ependymoma.
    Proc Natl Acad Sci U S A. 2025;122:e2319474122.
    PubMed     Abstract available
    
    
    
27. FURTH N, Cohen N, Spitzer A, Salame TM, et al
    Oncogenic IDH1(mut) drives robust loss of histone acetylation and increases chromatin heterogeneity.
    Proc Natl Acad Sci U S A. 2025;122:e2403862122.
    PubMed     Abstract available
    
    
    December 2024
28. HSIEH AL, Ganesh S, Kula T, Irshad M, et al
    Widespread neuroanatomical integration and distinct electrophysiological properties of glioma-innervating neurons.
    Proc Natl Acad Sci U S A. 2024;121:e2417420121.
    PubMed     Abstract available
    
    
    August 2024
29. 
    Correction for Kudruk et al., Multimodal neuro-nanotechnology: Challenging the existing paradigm in glioblastoma therapy.
    Proc Natl Acad Sci U S A. 2024;121:e2413733121.
    PubMed    
    
    
    June 2024
30. HUA W, Zhang W, Brown H, Wu J, et al
    Rapid detection of IDH mutations in gliomas by intraoperative mass spectrometry.
    Proc Natl Acad Sci U S A. 2024;121:e2318843121.
    PubMed     Abstract available
    
    
    May 2024
31. ASHOKAN A, Sarkar S, Kamran MZ, Surnar B, et al
    Simultaneous targeting of peripheral and brain tumors with a therapeutic nanoparticle to disrupt metabolic adaptability at both sites.
    Proc Natl Acad Sci U S A. 2024;121:e2318119121.
    PubMed     Abstract available
    
    
    
32. GOYETTE MA, Stevens LE, DePinho CR, Seehawer M, et al
    Cancer-stromal cell interactions in breast cancer brain metastases induce glycocalyx-mediated resistance to HER2-targeting therapies.
    Proc Natl Acad Sci U S A. 2024;121:e2322688121.
    PubMed     Abstract available
    
    
    April 2024
33. WU R, Sun C, Chen X, Yang R, et al
    NSUN5/TET2-directed chromatin-associated RNA modification of 5-methylcytosine to 5-hydroxymethylcytosine governs glioma immune evasion.
    Proc Natl Acad Sci U S A. 2024;121:e2321611121.
    PubMed     Abstract available
    
    
    March 2024
34. SAITO Y, Yang Y, Saito M, Park CY, et al
    NOVA1 acts as an oncogenic RNA-binding protein to regulate cholesterol homeostasis in human glioblastoma cells.
    Proc Natl Acad Sci U S A. 2024;121:e2314695121.
    PubMed     Abstract available
    
    
    February 2024
35. WANG R, Lei H, Wang H, Qi L, et al
    Dysregulated inter-mitochondrial crosstalk in glioblastoma cells revealed by in situ cryo-electron tomography.
    Proc Natl Acad Sci U S A. 2024;121:e2311160121.
    PubMed     Abstract available
    
    
    
36. NOCH EK, Palma L, Yim I, Bullen N, et al
    Cysteine induces mitochondrial reductive stress in glioblastoma through hydrogen peroxide production.
    Proc Natl Acad Sci U S A. 2024;121:e2317343121.
    PubMed     Abstract available
    
    
    
37. KUDRUK S, Forsyth CM, Dion MZ, Hedlund Orbeck JK, et al
    Multimodal neuro-nanotechnology: Challenging the existing paradigm in glioblastoma therapy.
    Proc Natl Acad Sci U S A. 2024;121:e2306973121.
    PubMed     Abstract available
    
    
    December 2023
38. WEN J, Nasrallah IM, Abdulkadir A, Satterthwaite TD, et al
    Genomic loci influence patterns of structural covariance in the human brain.
    Proc Natl Acad Sci U S A. 2023;120:e2300842120.
    PubMed     Abstract available
    
    
    September 2023
39. PANT A, Lim M
    Overcoming EGFR inhibitor resistance in Glioblastoma by targeting co-amplified genes.
    Proc Natl Acad Sci U S A. 2023;120:e2312277120.
    PubMed    
    
    
    August 2023
40. ROY A, Sakthikumar S, Kozyrev SV, Nordin J, et al
    Using evolutionary constraint to define novel candidate driver genes in medulloblastoma.
    Proc Natl Acad Sci U S A. 2023;120:e2300984120.
    PubMed     Abstract available
    
    
    
41. VOUTYRAKI C, Choromidis A, Meligkounaki A, Vlachopoulos NA, et al
    Growth deregulation and interaction with host hemocytes contribute to tumor progression in a Drosophila brain tumor model.
    Proc Natl Acad Sci U S A. 2023;120:e2221601120.
    PubMed     Abstract available
    
    
    
42. ZENG K, Zeng Y, Zhan H, Zhan Z, et al
    SEC61G assists EGFR-amplified glioblastoma to evade immune elimination.
    Proc Natl Acad Sci U S A. 2023;120:e2303400120.
    PubMed     Abstract available
    
    
    May 2023
43. RAVIRAM R, Raman A, Preissl S, Ning J, et al
    Integrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneity.
    Proc Natl Acad Sci U S A. 2023;120:e2210991120.
    PubMed     Abstract available
    
    
    
44. WANG F, Huang Q, Su H, Sun M, et al
    Self-assembling paclitaxel-mediated stimulation of tumor-associated macrophages for postoperative treatment of glioblastoma.
    Proc Natl Acad Sci U S A. 2023;120:e2204621120.
    PubMed     Abstract available
    
    
    
45. MOTA M, Sweha SR, Pun M, Natarajan SK, et al
    Targeting SWI/SNF ATPases in H3.3K27M diffuse intrinsic pontine gliomas.
    Proc Natl Acad Sci U S A. 2023;120:e2221175120.
    PubMed     Abstract available
    
    
    April 2023
46. MISHRA-GORUR K, Barak T, Kaulen LD, Henegariu O, et al
    Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease.
    Proc Natl Acad Sci U S A. 2023;120:e2214997120.
    PubMed     Abstract available
    
    
    
47. CHIPMAN ME, Wang Z, Sun D, Pedraza AM, et al
    Tumor progression is independent of tumor-associated macrophages in cell lineage-based mouse models of glioblastoma.
    Proc Natl Acad Sci U S A. 2023;120:e2222084120.
    PubMed     Abstract available
    
    

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