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  Neoplasms of the CNS

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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 38 articles:
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Single Articles


    November 2025

  1. Correction for Goyette et al., Cancer-stromal cell interactions in breast cancer brain metastases induce glycocalyx-mediated resistance to HER2-targeting therapies.
    Proc Natl Acad Sci U S A. 2025;122:e2530590122.
    PubMed    


  2. MAHAJAN AS, Dussold C, Kim S, Jarvis R, et al
    cGAS-agonistic spherical nucleic acids reprogram the glioblastoma immune microenvironment and promote antitumor immunity.
    Proc Natl Acad Sci U S A. 2025;122:e2409557122.
    PubMed     Abstract available


  3. MELSSEN M, Dimberg A
    Keeping Wnt in check for efficient checkpoint blockade in glioblastoma.
    Proc Natl Acad Sci U S A. 2025;122:e2523639122.
    PubMed    


    September 2025
  4. KRISHNAN S, Lee S, Amoozgar Z, Subudhi S, et al
    Wnt inhibition alleviates resistance to anti-PD1 therapy and improves antitumor immunity in glioblastoma.
    Proc Natl Acad Sci U S A. 2025;122:e2414941122.
    PubMed     Abstract available


  5. KEAHI DL, Sanders MA, Paul MR, Webster ALH, et al
    G-quadruplexes as a source of vulnerability in BRCA2-deficient granule cell progenitors and medulloblastoma.
    Proc Natl Acad Sci U S A. 2025;122:e2503872122.
    PubMed     Abstract available


    August 2025
  6. KHAN F, Liu Y, Whitfield D, Pang L, et al
    Macrophage TBK1 signaling drives the development and outgrowth of breast cancer brain metastasis.
    Proc Natl Acad Sci U S A. 2025;122:e2420793122.
    PubMed     Abstract available


    July 2025
  7. ZHOU L, Song Q, Zhang X, Cao M, et al
    In vivo generation of CAR macrophages via the enucleated mesenchymal stem cell delivery system for glioblastoma therapy.
    Proc Natl Acad Sci U S A. 2025;122:e2426724122.
    PubMed     Abstract available


  8. ZHU Z, Wang H, Li T, Huang TM, et al
    OMT and tensor SVD-based deep learning model for segmentation and predicting genetic markers of glioma: A multicenter study.
    Proc Natl Acad Sci U S A. 2025;122:e2500004122.
    PubMed     Abstract available


    June 2025

  9. Correction for Feng et al., Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis.
    Proc Natl Acad Sci U S A. 2025;122:e2511499122.
    PubMed    


    May 2025

  10. Correction to Supporting Information for Jensen et al., Bcl2L13 is a ceramide synthase inhibitor in glioblastoma.
    Proc Natl Acad Sci U S A. 2025;122:e2507673122.
    PubMed    


  11. ZHANG L, Yang J, Zhou Z, Ren Y, et al
    A zinc transporter drives glioblastoma progression via extracellular vesicles-reprogrammed microglial plasticity.
    Proc Natl Acad Sci U S A. 2025;122:e2427073122.
    PubMed     Abstract available


    April 2025

  12. Correction for He et al., Radiation-induced cellular plasticity primes glioblastoma for forskolin-mediated differentiation.
    Proc Natl Acad Sci U S A. 2025;122:e2506044122.
    PubMed    


    March 2025

  13. Correction for Xu et al., BCL6 promotes glioma and serves as a therapeutic target.
    Proc Natl Acad Sci U S A. 2025;122:e2504152122.
    PubMed    


  14. DI CARO V, Cesari P, Sala F, Cattaneo L, et al
    The neural bases of the reach-grasp movement in humans: Quantitative evidence from brain lesions.
    Proc Natl Acad Sci U S A. 2025;122:e2419801122.
    PubMed     Abstract available


  15. HE L, Azizad D, Bhat K, Ioannidis A, et al
    Radiation-induced cellular plasticity primes glioblastoma for forskolin-mediated differentiation.
    Proc Natl Acad Sci U S A. 2025;122:e2415557122.
    PubMed     Abstract available


    February 2025
  16. LI J, Shih LK, Markwell SM, Olson CL, et al
    A clinically relevant model and method to study necrosis as a driving force in glioma restructuring and progression.
    Proc Natl Acad Sci U S A. 2025;122:e2416024122.
    PubMed     Abstract available


    January 2025
  17. REN J, Amoozgar Z, Uccello TP, Lei PJ, et al
    Targeting EPHB2/ABL1 restores antitumor immunity in preclinical models of ependymoma.
    Proc Natl Acad Sci U S A. 2025;122:e2319474122.
    PubMed     Abstract available


  18. FURTH N, Cohen N, Spitzer A, Salame TM, et al
    Oncogenic IDH1(mut) drives robust loss of histone acetylation and increases chromatin heterogeneity.
    Proc Natl Acad Sci U S A. 2025;122:e2403862122.
    PubMed     Abstract available


    December 2024
  19. HSIEH AL, Ganesh S, Kula T, Irshad M, et al
    Widespread neuroanatomical integration and distinct electrophysiological properties of glioma-innervating neurons.
    Proc Natl Acad Sci U S A. 2024;121:e2417420121.
    PubMed     Abstract available


    August 2024

  20. Correction for Kudruk et al., Multimodal neuro-nanotechnology: Challenging the existing paradigm in glioblastoma therapy.
    Proc Natl Acad Sci U S A. 2024;121:e2413733121.
    PubMed    


    June 2024
  21. HUA W, Zhang W, Brown H, Wu J, et al
    Rapid detection of IDH mutations in gliomas by intraoperative mass spectrometry.
    Proc Natl Acad Sci U S A. 2024;121:e2318843121.
    PubMed     Abstract available


    May 2024
  22. ASHOKAN A, Sarkar S, Kamran MZ, Surnar B, et al
    Simultaneous targeting of peripheral and brain tumors with a therapeutic nanoparticle to disrupt metabolic adaptability at both sites.
    Proc Natl Acad Sci U S A. 2024;121:e2318119121.
    PubMed     Abstract available


  23. GOYETTE MA, Stevens LE, DePinho CR, Seehawer M, et al
    Cancer-stromal cell interactions in breast cancer brain metastases induce glycocalyx-mediated resistance to HER2-targeting therapies.
    Proc Natl Acad Sci U S A. 2024;121:e2322688121.
    PubMed     Abstract available


    April 2024
  24. WU R, Sun C, Chen X, Yang R, et al
    NSUN5/TET2-directed chromatin-associated RNA modification of 5-methylcytosine to 5-hydroxymethylcytosine governs glioma immune evasion.
    Proc Natl Acad Sci U S A. 2024;121:e2321611121.
    PubMed     Abstract available


    March 2024
  25. SAITO Y, Yang Y, Saito M, Park CY, et al
    NOVA1 acts as an oncogenic RNA-binding protein to regulate cholesterol homeostasis in human glioblastoma cells.
    Proc Natl Acad Sci U S A. 2024;121:e2314695121.
    PubMed     Abstract available


    February 2024
  26. WANG R, Lei H, Wang H, Qi L, et al
    Dysregulated inter-mitochondrial crosstalk in glioblastoma cells revealed by in situ cryo-electron tomography.
    Proc Natl Acad Sci U S A. 2024;121:e2311160121.
    PubMed     Abstract available


  27. NOCH EK, Palma L, Yim I, Bullen N, et al
    Cysteine induces mitochondrial reductive stress in glioblastoma through hydrogen peroxide production.
    Proc Natl Acad Sci U S A. 2024;121:e2317343121.
    PubMed     Abstract available


  28. KUDRUK S, Forsyth CM, Dion MZ, Hedlund Orbeck JK, et al
    Multimodal neuro-nanotechnology: Challenging the existing paradigm in glioblastoma therapy.
    Proc Natl Acad Sci U S A. 2024;121:e2306973121.
    PubMed     Abstract available


    December 2023
  29. WEN J, Nasrallah IM, Abdulkadir A, Satterthwaite TD, et al
    Genomic loci influence patterns of structural covariance in the human brain.
    Proc Natl Acad Sci U S A. 2023;120:e2300842120.
    PubMed     Abstract available


    September 2023
  30. PANT A, Lim M
    Overcoming EGFR inhibitor resistance in Glioblastoma by targeting co-amplified genes.
    Proc Natl Acad Sci U S A. 2023;120:e2312277120.
    PubMed    


    August 2023
  31. ROY A, Sakthikumar S, Kozyrev SV, Nordin J, et al
    Using evolutionary constraint to define novel candidate driver genes in medulloblastoma.
    Proc Natl Acad Sci U S A. 2023;120:e2300984120.
    PubMed     Abstract available


  32. VOUTYRAKI C, Choromidis A, Meligkounaki A, Vlachopoulos NA, et al
    Growth deregulation and interaction with host hemocytes contribute to tumor progression in a Drosophila brain tumor model.
    Proc Natl Acad Sci U S A. 2023;120:e2221601120.
    PubMed     Abstract available


  33. ZENG K, Zeng Y, Zhan H, Zhan Z, et al
    SEC61G assists EGFR-amplified glioblastoma to evade immune elimination.
    Proc Natl Acad Sci U S A. 2023;120:e2303400120.
    PubMed     Abstract available


    May 2023
  34. RAVIRAM R, Raman A, Preissl S, Ning J, et al
    Integrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneity.
    Proc Natl Acad Sci U S A. 2023;120:e2210991120.
    PubMed     Abstract available


  35. WANG F, Huang Q, Su H, Sun M, et al
    Self-assembling paclitaxel-mediated stimulation of tumor-associated macrophages for postoperative treatment of glioblastoma.
    Proc Natl Acad Sci U S A. 2023;120:e2204621120.
    PubMed     Abstract available


  36. MOTA M, Sweha SR, Pun M, Natarajan SK, et al
    Targeting SWI/SNF ATPases in H3.3K27M diffuse intrinsic pontine gliomas.
    Proc Natl Acad Sci U S A. 2023;120:e2221175120.
    PubMed     Abstract available


    April 2023
  37. MISHRA-GORUR K, Barak T, Kaulen LD, Henegariu O, et al
    Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease.
    Proc Natl Acad Sci U S A. 2023;120:e2214997120.
    PubMed     Abstract available


  38. CHIPMAN ME, Wang Z, Sun D, Pedraza AM, et al
    Tumor progression is independent of tumor-associated macrophages in cell lineage-based mouse models of glioblastoma.
    Proc Natl Acad Sci U S A. 2023;120:e2222084120.
    PubMed     Abstract available


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