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Articles published in Anticancer Res

Retrieve available abstracts of 165 articles:
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Single Articles


    September 2026
  1. KAMADA T, Takano Y, Goto K, Tsukihara S, et al
    High Cancer Inflammation Prognostic Index Identifies Patients With Stage II Colorectal Cancer With Outcomes Comparable to Stage III.
    Anticancer Res. 2026;46:5205-5215.
    PubMed     Abstract available


  2. YAGYU T, Yamamoto M, Tsuda A, Ashida K, et al
    Lymphocyte Count Predicts Adjuvant Chemotherapy Completion After Severe Postoperative Complications in Colorectal Cancer.
    Anticancer Res. 2026;46:5055-5065.
    PubMed     Abstract available


  3. ISHIKAWA I, Takagi K, Fuji T, Yasui K, et al
    Technical Considerations of the Jejunal Limb Route During Pancreaticoduodenectomy Following Total Colectomy for Familial Adenomatous Polyposis: A Case Report and Literature Review.
    Anticancer Res. 2026;46:5311-5317.
    PubMed     Abstract available


  4. KIM JS, Im CM, Oh HH, Park SY, et al
    Malformin A1 Enhances 5-Fluorouracil-induced Apoptosis, Cell Cycle Arrest, and Anti-angiogenesis in Colorectal Cancer Cells.
    Anticancer Res. 2026;46:4959-4972.
    PubMed     Abstract available


  5. IKUTA S, Aihara T, Nakajima T, Iwasaki T, et al
    Repeat Hepatectomy Versus Thermal Ablation for Intrahepatic Recurrence After Resection of Colorectal Liver Metastases: A Propensity-adjusted Analysis With Multiple Imputation.
    Anticancer Res. 2026;46:5281-5287.
    PubMed     Abstract available


  6. YUSA T, Masuda T, Tomiguchi M, Nagayama Y, et al
    A Case of Concurrent Liver Metastases from Colorectal and Breast Cancer Diagnosed Using Percutaneous Tumor Biopsy.
    Anticancer Res. 2026;46:5339-5345.
    PubMed     Abstract available


    August 2026
  7. SUZUKI H, Okuda H, Saito H, Tsuji T, et al
    CD44 Translocates in the Nucleus of Tumor Cells in a Colitis-associated Colorectal Cancer Mouse Model.
    Anticancer Res. 2026;46:4193-4202.
    PubMed     Abstract available


  8. KITAGUCHI T, Abe S, Matsumoto T, Yoshida K, et al
    Pyra-Metho-Carnil Suppresses CD73-associated Macrophage Infiltration in KRAS-mutant Colorectal Cancer.
    Anticancer Res. 2026;46:4649-4663.
    PubMed     Abstract available


  9. KAMADA T, Takano Y, Goto K, Tsukihara S, et al
    A Preoperative Symptom-tumor-nutrition Score Predicting Survival After Laparoscopic Resection for Colorectal Cancer.
    Anticancer Res. 2026;46:4499-4507.
    PubMed     Abstract available


  10. KINUGASA T, Matsumoto T, Okada T, Sudo T, et al
    MUC5AC, CEACAM7, and DUOX2 Distinguish Colitis-associated Cancer from Sporadic Colorectal Cancer.
    Anticancer Res. 2026;46:4707-4717.
    PubMed     Abstract available


  11. YOSHIDA N, Takamatsu M, Takaki K, Hisada K, et al
    Analysis for IL-22/ IL-22BP Axis and Cell Adhesion Molecules in Advanced Colorectal Cancer.
    Anticancer Res. 2026;46:4627-4637.
    PubMed     Abstract available


  12. WANG S, Minagawa T, Toyoda Y, Sadanaga T, et al
    Leucine-rich KQLLL Motif Coordinates Secretion, Nuclear Localization, and Proliferation of Chitinase 3-like 1.
    Anticancer Res. 2026;46:4681-4687.
    PubMed     Abstract available


    July 2026
  13. MA R, Shimura T, Huang Y, Yoshimura K, et al
    Anti-tumor Effects of Loureirin A Treatment in Colorectal Cancer Cells via Inhibition of AKT Phosphorylation.
    Anticancer Res. 2026;46:3627-3638.
    PubMed     Abstract available


  14. DEMIRORS B, Godbole N, Brock LF, Bowers JC, et al
    Geographic Disparities in Socioeconomic Factors and Advanced-stage Presentation in Rectosigmoid Cancer: A National Cancer Database Analysis.
    Anticancer Res. 2026;46:3871-3878.
    PubMed     Abstract available


  15. SHIBUTANI M, Seki Y, Kasashima H, Maeda K, et al
    Surgical Treatment and Postoperative Surveillance for Familial Adenomatous Polyposis.
    Anticancer Res. 2026;46:3583-3591.
    PubMed     Abstract available


  16. KUO TC, Wang WC, Hsiao WP, Yen Y, et al
    Association Between Body Mass Index and Overall Survival in Patients With Colorectal Cancer in Taiwan.
    Anticancer Res. 2026;46:4139-4150.
    PubMed     Abstract available


    June 2026
  17. FUNAKOSHI K, Sasaki K, Hata K, Nozawa H, et al
    Genomic Profiling of Cancerous Areas, Dysplasia, and Background Mucosa in Ulcerative Colitis-associated Colorectal Cancer.
    Anticancer Res. 2026;46:3281-3291.
    PubMed     Abstract available


  18. MAEDA K, Koyama S, Kawada K, Hayashi T, et al
    Fosnetupitant Versus Fosaprepitant for Delayed Vomiting Upon Irinotecan-Oxaliplatin Combination Chemotherapy for Pancreatic/Colorectal Cancer.
    Anticancer Res. 2026;46:3191-3203.
    PubMed     Abstract available


  19. RAFIQUE A, Koh YS
    Unveiling the Anti-tumor Actions and Therapeutic Potential of Calcitriol in Colorectal Cancer.
    Anticancer Res. 2026;46:2985-3004.
    PubMed     Abstract available


  20. MURAI Y, Sugimoto K, Irie T, Fujisaki T, et al
    Circulating Tumor DNA Methylation Level Is a More Accurate Prognostic Biomarker in Colon Cancer.
    Anticancer Res. 2026;46:3267-3280.
    PubMed     Abstract available


    May 2026
  21. SHIRAISHI T, Tominaga T, Nonaka T, Takamura Y, et al
    Prognostic Significance of the Lymph Node Ratio in Obstructive Colorectal Cancer: A Retrospective Multicenter Study.
    Anticancer Res. 2026;46:2703-2711.
    PubMed     Abstract available


  22. ISHII K, Tauchi Y, Yano T
    Evaluation of Combined Treatment With Atorvastatin and SREBP2 Inhibitors Against Colorectal Cancer Cells Under Two-dimensional and Three-dimensional Culture Models.
    Anticancer Res. 2026;46:2403-2415.
    PubMed     Abstract available


  23. SALIMIAGHDAM N, Yang X, Liang H
    The Ovarian Portal: An Unusual Pathway to Discovery, A Rare Initial Manifestation of Colon Cancer.
    Anticancer Res. 2026;46:2915-2923.
    PubMed     Abstract available


  24. ADACHI Y, Matsuda T, Inubushi S, Yasuda K, et al
    Serum Extracellular Vesicles Double-positive for CD9 and CD147 or for CD9 and CD63 Decrease After Surgical Resection in Patients With Colorectal Cancer: Potential Biomarkers of Residual Tumor.
    Anticancer Res. 2026;46:2345-2352.
    PubMed     Abstract available


  25. KYROS E, Mylonakis A, Kastanaki P, Velliou RI, et al
    Cytometry by Time-of-Flight for Profiling Therapeutic Response in Colorectal Cancer: Strengths, Limitations, and Translational Challenges.
    Anticancer Res. 2026;46:2297-2316.
    PubMed     Abstract available


  26. KOBAYASHI Y, Takano Y, Fukushima A, Takishima T, et al
    Prognostic Impact of the Geriatric Nutritional Risk Index in Elderly Patients With Colorectal Cancer.
    Anticancer Res. 2026;46:2753-2762.
    PubMed     Abstract available


  27. ISHII K, Yano T
    6-O-Carboxypropyl-alpha-Tocotrienol Enhances the Anticancer Effects of Bortezomib Without Suppressing NRF1 and NRF3 in Colorectal Cancer Cells.
    Anticancer Res. 2026;46:2375-2386.
    PubMed     Abstract available


  28. KIM J, Han Q, Li S, Kang BM, et al
    Sulfasalazine an Inhibitor of System x(C) (-) (Cystine/glutamate Antiporter), Combined With Recombinant Methioninase, Inhibits Both Cancer and Normal Cells, Suggesting Lack of Cancer Selectivity of Cysteine Restriction.
    Anticancer Res. 2026;46:2353-2359.
    PubMed     Abstract available


  29. KOMORI K, Kinoshita T, Ouchi A, Kishida T, et al
    Laparotomy After Total Pelvic Exenteration: Current Status and Techniques for Ileal Conduit Preservation.
    Anticancer Res. 2026;46:2735-2741.
    PubMed     Abstract available


  30. ZHANG Z, Tu H, Han Z, Wang S, et al
    Profiling of Lysine Lactylation Reveals Its Proliferation-promoting Functions in Colorectal Cancer Cells.
    Anticancer Res. 2026;46:2565-2581.
    PubMed     Abstract available


  31. THI TN, Nguyen VT, Thanh HD, Kwon SY, et al
    Inhibition of AP-1 Reduces CD46-mediated Invasion of Bladder and Colon Cancer Cells.
    Anticancer Res. 2026;46:2525-2539.
    PubMed     Abstract available


  32. MATOBA D, Saito T, Noda T, Uemura M, et al
    PD-1(+)Tim-3(+)CD103(+) CD8(+) Tumor-infiltrating Lymphocytes Are Associated With Favorable Outcomes in Colorectal Cancer.
    Anticancer Res. 2026;46:2387-2401.
    PubMed     Abstract available


    April 2026
  33. KONDOR AE, Vereczkei A, Varga P, Sindler LD, et al
    The Role of MRI in the Preoperative Staging of Rectal Cancer: Ten-year Experience from a Single Tertiary Center.
    Anticancer Res. 2026;46:2125-2132.
    PubMed     Abstract available


  34. SAELIM P, Ei ZZ, Racha S, Yokoya M, et al
    Methoxy and Ketone Substitutions of Resveratrol Enhance Its Anticancer Activity by Increasing MEK and ERK Binding Affinity in Colorectal Cancer Cells.
    Anticancer Res. 2026;46:1957-1966.
    PubMed     Abstract available


  35. KATAYAMA R, Aoki T, Tashiro Y, Hirai T, et al
    Relationship Between Histopathological Growth Patterns and Indocyanine Green Fluorescence in Colorectal Liver Metastases.
    Anticancer Res. 2026;46:2087-2093.
    PubMed     Abstract available


    March 2026
  36. LOPES C, Macedo-Silva C, Farinha M, Costa J, et al
    Exploring SLC1A5 (ASCT2), SLC7A5, and SLC3A2 (LAT1) Genetic Variants in Colorectal Cancer: Implications for Prognosis and Personalized Care.
    Anticancer Res. 2026;46:1281-1292.
    PubMed     Abstract available


  37. MAIMON O, Nisman B, Ben-David I, Kuznetz A, et al
    Autologous Tumor Vaccination in Melanoma and Colon Cancer Patients With Recurrent Liver Metastases: A Case Series.
    Anticancer Res. 2026;46:1569-1575.
    PubMed     Abstract available


  38. GKEKAS I, Novotny J, Kaprio T, Fabian P, et al
    Risk of Non-colorectal Malignancies in Sporadic Versus Lynch Syndrome-associated dMMR Colorectal Cancer.
    Anticancer Res. 2026;46:1489-1496.
    PubMed     Abstract available


  39. KAUR H, Bhall GIS, Lauder C, DA Silva N, et al
    Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Outcomes for Colorectal and Mesothelioma Peritoneal Metastases: A 12-year Study.
    Anticancer Res. 2026;46:1507-1515.
    PubMed     Abstract available


  40. TAKCI RG, Sarac B, Hacisuleyman L, Sahinbas B, et al
    Synergistic Anticancer Effects of the PLK1 Inhibitor BI-2536 and beta-Glucan in Colon and Gastric Cancer Cells.
    Anticancer Res. 2026;46:1461-1474.
    PubMed     Abstract available


    February 2026
  41. KIM J, Han Q, Li S, Kang BM, et al
    Lack of Cancer Specificity of Methionine Adenosyltransferase 2A (MAT2A) Inhibitor AG-270 in Combination With Recombinant Methioninase In Vitro.
    Anticancer Res. 2026;46:705-712.
    PubMed     Abstract available


  42. TANDA H, Shibutani M, Seki Y, Nishiyama T, et al
    The Usefulness of the Modified Controlling Nutritional Status Score for Assessing Prognosis in Patients With Colorectal Cancer.
    Anticancer Res. 2026;46:1097-1105.
    PubMed     Abstract available


  43. YAMANAKA R, Matsumoto N, Murase R, Kubota Y, et al
    Polymorphisms of FGFR Pathway-related Factors and Capecitabine-induced Hand-foot Syndrome in Japanese Patients With Colorectal Cancer.
    Anticancer Res. 2026;46:835-846.
    PubMed     Abstract available


  44. OKADO S, Nakamura S, Sugihara M, Kinoshita F, et al
    Prognostic Factors for Pulmonary Metastasectomy for Colorectal Cancer: A Propensity Score Matching Analysis.
    Anticancer Res. 2026;46:1143-1152.
    PubMed     Abstract available


  45. KUWATA D, Shimoda H, Miura T, Chiba T, et al
    Anatomical-specific Lymphatic Route Beyond Mesorectal Fascia: Analyses from Female Cadavers and Patients With Rectal Cancer.
    Anticancer Res. 2026;46:885-899.
    PubMed     Abstract available


  46. INOUE A, Ota H, Matsuura Y, Munakata K, et al
    First-line FOLFOXIRI-based Chemotherapy for Unresectable Metastatic Colorectal Cancer: Real-world Outcomes, Safety, and Conversion Surgery.
    Anticancer Res. 2026;46:975-985.
    PubMed     Abstract available


  47. SEKI Y, Shibutani M, Tanda H, Tsukida T, et al
    Impact of the Immunonutritional Status on the Feasibility of Subsequent Treatment After the Discontinuation of Trifluridine-Tipiracil Plus Bevacizumab Therapy in Patients With Metastatic Colorectal Cancer.
    Anticancer Res. 2026;46:1117-1122.
    PubMed     Abstract available


  48. KIM HB, Lee HJ, Park SG
    Oncogenic Role and Clinical Significance of NPM1 in Colorectal Cancer via the AKT/mTOR Signaling Pathway.
    Anticancer Res. 2026;46:727-736.
    PubMed     Abstract available


  49. KUO CY, Liao TL, Hsu FT, Chang CM, et al
    Lenvatinib Exhibits Potent Anti-tumor Activity and Favorable Safety Profile in a Colorectal Cancer Xenograft Model.
    Anticancer Res. 2026;46:797-810.
    PubMed     Abstract available


    January 2026
  50. KOSUGE T, Mazaki J, Kasahara K, Osakabe H, et al
    Prediction of the Clinicopathological Prognosis of Colon Cancer After Radical Resection Using Artificial Intelligence "TabNet".
    Anticancer Res. 2026;46:467-474.
    PubMed     Abstract available


  51. NARIHIRO S, Kitaguchi D, Ryu S, Fukuda M, et al
    Short-term Outcomes of Robotic-assisted Versus Laparoscopic Right Hemicolectomy for Right-sided Colon Cancer: A Retrospective Study.
    Anticancer Res. 2026;46:493-501.
    PubMed     Abstract available


  52. KIM BH, Lee J, Lee D, Kim K, et al
    Immune Microenvironment Signatures Predict Response and Survival in Rectal Cancer Patients After Neoadjuvant Chemoradiation.
    Anticancer Res. 2026;46:123-134.
    PubMed     Abstract available


  53. MATSUBARA D, Soga K, Fujita Y, Ochi F, et al
    Oncological Outcomes of Laparoscopic Surgery With Stent Bridge in Stage II-III Obstructive Colorectal Cancer.
    Anticancer Res. 2026;46:347-357.
    PubMed     Abstract available


  54. KATAYAMA H, Noda K, Tominaga T, Hashimoto S, et al
    Effect of the Endoscopic Surgical Skill Qualification System for Colorectal Cancer Surgery With Multivisceral Resection on Long-term Outcomes: Japanese Multicenter Analysis.
    Anticancer Res. 2026;46:457-465.
    PubMed     Abstract available


  55. NODA K, Tominaga T, Hashimoto S, Yamashita M, et al
    Effect of Pathological Response After Neoadjuvant Chemotherapy on Long-term Outcomes in Locally Advanced Colorectal Cancer: A Japanese Multicenter Study.
    Anticancer Res. 2026;46:327-336.
    PubMed     Abstract available


  56. OHTAKI KI, Takeuchi R, Iwayama K, Chuma M, et al
    Evaluation of Regorafenib-induced Pancreatic Enzyme Elevation in Metastatic Colorectal Cancer Treatment.
    Anticancer Res. 2026;46:359-369.
    PubMed     Abstract available


    December 2025
  57. MUECKE R, Fakhrian K, Gosenheimer R, Schmitz V, et al
    Neoadjuvant Radiochemotherapy for Locally Advanced Rectal Cancer: A Single-institutional Real-world Study.
    Anticancer Res. 2025;45:5513-5521.
    PubMed     Abstract available


  58. KIM J, Han Q, Li S, Kang BM, et al
    The Combination of Recombinant Methioninase and Low-dose Chloroquine Selectively Eradicates Colon-Cancer Cells Without Apparent Toxicity on Co-cultured Normal Fibroblasts.
    Anticancer Res. 2025;45:5313-5320.
    PubMed     Abstract available


  59. FURUKAWA K, Haruki K, Shirai Y, Onda S, et al
    Pulmonary Emphysema Assessed by the Goddard Score Predicts Outcomes After Hepatic Resection for Colorectal Liver Metastases.
    Anticancer Res. 2025;45:5765-5772.
    PubMed     Abstract available


  60. YONEMITSU K, Kasashima H, Fukuoka T, Tanaka A, et al
    Successful Reconstruction of Recurrent Perineal Hernia After APR Using a Vertical Rectus Abdominis Myocutaneous Flap: A Salvage Option for a Refractory Case.
    Anticancer Res. 2025;45:5813-5817.
    PubMed     Abstract available


    November 2025
  61. KOTAKE Y, Tanigawa Y, Ikenaga H, Kitagawa T, et al
    OIP5-AS1 Positively Regulates the Proliferation of Colorectal Cancer Cells by Repressing Apoptosis.
    Anticancer Res. 2025;45:4783-4790.
    PubMed     Abstract available


  62. KIM MW, Kim D, Lee SE, Ahn J, et al
    JI-CJ002, a Natural Herbal Formula, Enhances the Antitumor Efficacy of FOLFOX in Colorectal Cancer by Suppressing the DDR Pathway.
    Anticancer Res. 2025;45:4987-5000.
    PubMed     Abstract available


  63. MARUTA H, Noda K, Tominaga T, Hashimoto S, et al
    Efficacy and Safety of Robotic Surgery for Bulky Colorectal Tumors.
    Anticancer Res. 2025;45:5139-5146.
    PubMed     Abstract available


  64. SHIMASAKI M, Kiyozumi Y, Ohmura R, Matsuishi K, et al
    Pathological Complete Response in Locally-advanced MSI-H/dMMR Sigmoid Colon Cancer Treated With Pembrolizumab and Abdominal Reconstruction.
    Anticancer Res. 2025;45:5239-5246.
    PubMed     Abstract available


  65. TSAI YF, Wu MH, Lin TC, Yueh TC, et al
    Contribution of Xeroderma Pigmentosum Complementation Group C Genotypes to Colorectal Cancer in Taiwanese.
    Anticancer Res. 2025;45:4751-4763.
    PubMed     Abstract available


  66. KITAGUCHI D, Enomoto T, Hoshiai S, Furuya K, et al
    Preoperative Risk Analysis for Postoperative Recurrence in Locally Advanced Rectal Cancer Following Chemoradiotherapy.
    Anticancer Res. 2025;45:5147-5157.
    PubMed     Abstract available


  67. HOSOKAWA A, Yamada R, Otsuki Y, Tamura H, et al
    Remarkable and Durable Tumor Response to Pembrolizumab in Locally Advanced dMMR/MSI-H Rectal Cancer.
    Anticancer Res. 2025;45:5069-5076.
    PubMed     Abstract available


    October 2025
  68. TAKAHASHI H, Kojima D, Miyasaka Y, Wada H, et al
    Neoadjuvant Chemotherapy for Initially Resectable Metachronous Colorectal Cancer Liver Metastases Is Associated With Early Postoperative Relapse.
    Anticancer Res. 2025;45:4547-4564.
    PubMed     Abstract available


  69. JIMENEZ PB, Merly AA, Shekouhi R, Demirors B, et al
    Survival Impact and Sociodemographic Correlates of Colon Cancer Surgery Refusal.
    Anticancer Res. 2025;45:4305-4313.
    PubMed     Abstract available


  70. KANG BM, Han Q, Li S, Kim JS, et al
    Recombinant Methioninase Selectively Eliminates Cancer Cells Co-cultured With Normal Fibroblasts Indicating the High-Precision Efficacy of Targeting Methionine Addiction of Cancer.
    Anticancer Res. 2025;45:4193-4200.
    PubMed     Abstract available


  71. FUKATA K, Ogura A, Murata Y, Kobayashi R, et al
    The Impact of Adjuvant Chemotherapy in Patients With Locally Advanced Rectal Cancer After Neoadjuvant Chemotherapy: A Propensity Score Matching Cohort Study.
    Anticancer Res. 2025;45:4431-4439.
    PubMed     Abstract available


  72. CIFTCI M, Ozgur E, Kulle CB, Gezer U, et al
    Exploring the Clinical Significance of Circulating H19 lncRNA and IGF-2 mRNA in Colorectal Carcinoma.
    Anticancer Res. 2025;45:4243-4251.
    PubMed     Abstract available


  73. HARISI R, Jaray B, Zsirka A, Kulka J, et al
    Differential PCNA Expression Between Neoplastic and Adjacent Mucosa as a Prognostic Marker in Colorectal Adenoma-Carcinoma Progression.
    Anticancer Res. 2025;45:4415-4430.
    PubMed     Abstract available


    September 2025
  74. WADA N, Nishida N, Takeda M, Sekido Y, et al
    Efficacy and Safety of S-1 and Oxaliplatin With Radiotherapy for Anorectal Cancer.
    Anticancer Res. 2025;45:3847-3857.
    PubMed     Abstract available


  75. OTANI K, Kazama K, Aoyama T, Hashimoto I, et al
    Geriatric Nutritional Risk Index Predicts Prognosis in Older Patients With Colorectal Cancer: A Multicenter Study.
    Anticancer Res. 2025;45:4015-4025.
    PubMed     Abstract available


  76. KOKAINE L, Daneberga Z, Satcs M, Zvina D, et al
    The Prognostic Role of microRNAs 142-5p, 182-3p, and 99a-3p in Locally Advanced Rectal Cancer Patients.
    Anticancer Res. 2025;45:3895-3912.
    PubMed     Abstract available


  77. KIM J, Han Q, Li S, Kang BM, et al
    Combinations of Salmonella typhimurium A1-R, Recombinant Methioninase, and Chloroquine, Each Targeting Fundamental Cancer Hallmarks, Are Selectively Effective on Colon Cancer Cells Compared to Normal Fibroblasts.
    Anticancer Res. 2025;45:3661-3668.
    PubMed     Abstract available


  78. NOZAWA H, Kasuga SO, Murono K, Sasaki K, et al
    Effects of Neoadjuvant Treatments on Mesorectal Computed Tomography Values and Tumor Regression in Rectal Cancer.
    Anticancer Res. 2025;45:3921-3930.
    PubMed     Abstract available


  79. KIMURA N, Hiraki M, Furukawa S, Ikuno H, et al
    Oncological Outcomes of Varying Resection Margin Lengths in Colon Cancer Surgery: A Retrospective Analysis.
    Anticancer Res. 2025;45:4005-4013.
    PubMed     Abstract available


    August 2025
  80. OGURA A, Murata Y, Sando M, Kobayashi R, et al
    Response-guided Strategy Based on Induction Chemotherapy Without Routine Use of Radiotherapy for Locally Advanced Rectal Cancer.
    Anticancer Res. 2025;45:3393-3398.
    PubMed     Abstract available


  81. MUKOHYAMA J, Saito I, Mochizuki S, Ota Y, et al
    Endometrial Cancer Metastatic to the Sigmoid Colon and Pelvic Retroperitoneal Space: A Case Report.
    Anticancer Res. 2025;45:3567-3573.
    PubMed     Abstract available


  82. LEE S, Koh JW, Lee JH, Park SJ, et al
    Silencing of Acyl-CoA Thioesterase 7 Inhibits Proliferation and Metastatic Potential in Colorectal Cancer Cells.
    Anticancer Res. 2025;45:3315-3325.
    PubMed     Abstract available


    July 2025
  83. HUANG CW, Yang JS, Tsai YF, Kuo SC, et al
    Anti-cancer Effects of a Novel Curcumin Derivative, 4,4-Diallyl Curcumin Bis(2,2-Hydroxymethyl)Propanoate (35e), on Radio-resistant Colorectal Cancer Cells.
    Anticancer Res. 2025;45:2891-2904.
    PubMed     Abstract available


  84. ASANO Y, Han Q, Li S, Mizuta K, et al
    The Combination of the Autophagy Inhibitor Chloroquine and Recombinant Methioninase Has Selective Synergistic Efficacy on Human Colon Cancer Cells But Not on Normal Human Fibroblasts.
    Anticancer Res. 2025;45:2825-2831.
    PubMed     Abstract available


  85. KIM J, Han Q, Kang BM, Mizuta K, et al
    The Triple Combination of Recombinant Methioninase, Rapamycin, and Chloroquine Synergistically Eradicates HCT116 Colon Cancer Cells.
    Anticancer Res. 2025;45:2773-2779.
    PubMed     Abstract available


  86. LEE J, Kim H, Moon J, Nualsanit T, et al
    Damnacanthal Suppresses TCF4 Expression in Colorectal Cancer Cells.
    Anticancer Res. 2025;45:2847-2858.
    PubMed     Abstract available


  87. KANG BM, Han Q, Li S, Mizuta K, et al
    The Conditions of Non-rescuability of Methioninase-treated Cancer Cells by Methionine Replenishment: The Point of No Return.
    Anticancer Res. 2025;45:2817-2823.
    PubMed     Abstract available


  88. NGUYEN MLT, Bui LA, Pham C, Nham PLT, et al
    Adiponectin Receptor Agonist Suppresses Human Colorectal Cancer.
    Anticancer Res. 2025;45:3059-3068.
    PubMed     Abstract available


  89. VAN BUSSEL MTJ, Bravenboer N, Essen HV, Snaebjornsson P, et al
    Bone Toxicity Case Report Combining Encorafenib, Cetuximab and WNT974 in a Phase I Trial.
    Anticancer Res. 2025;45:3137-3147.
    PubMed     Abstract available


  90. SUETSUGU F, Tadokoro T, Fujita K, Fujihara S, et al
    Antitumor Effects of Epigallocatechin-3-Gallate on Colorectal Cancer: An In Vitro and In Vivo Study.
    Anticancer Res. 2025;45:2937-2947.
    PubMed     Abstract available


    June 2025
  91. MINAMI S, Miyoshi N, Fujino S, Yasui M, et al
    Role of the Circadian Clock Gene DEC1 in Chemosensitivity and Apoptosis in Colorectal Cancer.
    Anticancer Res. 2025;45:2309-2328.
    PubMed     Abstract available


  92. YU X, Tsunedomi R, Hazama S, Nakagami Y, et al
    Immunogenicity of Neoantigens in Colorectal Cancer: Potential Influence of Tumor Mutation Burden, Stages, and Metastasis.
    Anticancer Res. 2025;45:2385-2399.
    PubMed     Abstract available


  93. ANDO Y, Orito H, Mizuno T, Katsuno H, et al
    Effect of a Biweekly Dosing Schedule on Severe Neutropenia Induced by Trifluridine/Tipiracil in Colorectal Cancer.
    Anticancer Res. 2025;45:2587-2594.
    PubMed     Abstract available


  94. ESKELINEN M, Selander T, Guimaraes DP, Kaarniranta K, et al
    Four Different Artificial Intelligence Models Versus Logistic Regression to Enhance the Diagnostic Accuracy of Fecal Immunochemical Test in the Detection of Colorectal Carcinoma in a Screening Setting.
    Anticancer Res. 2025;45:2477-2491.
    PubMed     Abstract available


  95. KODAMA H, Yamaguchi T, Kameishi S, Kadono T, et al
    Tumor Budding Grade and T Stage as Recurrence Predictors of High-risk Stage II Colorectal Cancer.
    Anticancer Res. 2025;45:2619-2628.
    PubMed     Abstract available


  96. KATAOKA A, Kawasaki T, Kaira K, Hirano Y, et al
    Pathological Investigation of Grasping-related Mesenteric Injury During Laparoscopic Colorectal Cancer Resection.
    Anticancer Res. 2025;45:2493-2499.
    PubMed     Abstract available


  97. ASANO Y, Han Q, Li S, Mizuta K, et al
    Selective Synergy of Ivermectin Combined With Recombinant Methioninase Against Colon-Cancer Cells in Contrast to Normal Fibroblasts.
    Anticancer Res. 2025;45:2257-2263.
    PubMed     Abstract available


  98. KOBAYASHI Y, Takano Y, Matsukida S, Takishima T, et al
    Prognostic Nutritional Index Is the Key Prognostic Factor in Elderly Patients With Colorectal Cancer.
    Anticancer Res. 2025;45:2595-2603.
    PubMed     Abstract available


    May 2025
  99. HWANG HH, Yoo JS, Je JH, Lee HC, et al
    SH003 Inhibits Proliferation and Induces Apoptosis in Colon Cancer Through the RTK-STAT3 Pathway.
    Anticancer Res. 2025;45:1965-1980.
    PubMed     Abstract available


  100. IZUTANI Y, Ogino T, Fujii M, Sekido Y, et al
    Appendectomy Mitigates Ulcerative Colitis Activity and Delays Colorectal Cancer Onset: A Retrospective Cohort Study.
    Anticancer Res. 2025;45:2205-2214.
    PubMed     Abstract available


    April 2025
  101. OKEMOTO D, Yamaguchi T, Sugino K, Matsuo N, et al
    Chemotherapy Efficacy in Patients With Colorectal Cancer Experiencing Early Recurrence During or After Adjuvant Chemotherapy.
    Anticancer Res. 2025;45:1695-1705.
    PubMed     Abstract available


  102. YUEH TC, Chen YJ, Mong MC, Ke TW, et al
    The Contribution of Interleukin-12A and Interleukin-12B Genotypes to Colorectal Cancer in Taiwan.
    Anticancer Res. 2025;45:1501-1512.
    PubMed     Abstract available


  103. NII T, Yoshimi T, Tanito K, Hijii S, et al
    Inflammation-triggering Engineered Macrophages (MacTriggers) Are Promising Cell-based Therapeutic Avenues for Chemoresistant Solid Tumors.
    Anticancer Res. 2025;45:1395-1405.
    PubMed     Abstract available


  104. SUGIMOTO K, Irie T, Momose H, Kochi S, et al
    Circulating Tumor DNA Methylation Is a Biomarker of Poor Recurrence-free Survival in Locally-Advanced Rectal Cancer.
    Anticancer Res. 2025;45:1559-1573.
    PubMed     Abstract available


    March 2025
  105. TERAISHI F, Yoshida Y, Shoji R, Kanaya N, et al
    Short-term Safety of Robot-assisted Rectal Surgery in Patients Aged >/=75 Years: A Single-center Retrospective Study.
    Anticancer Res. 2025;45:1291-1299.
    PubMed     Abstract available


  106. WEISS TS, Buechler C
    Proprotein Convertase Subtilisin/Kexin Type 9 Induction in Hypercholesterinemic Patients With Primary and Metastatic Liver Tumors.
    Anticancer Res. 2025;45:1171-1180.
    PubMed     Abstract available


  107. SHOJI R, Teraishi F, Kondo Y, Yoshida Y, et al
    Tailoring Neoadjuvant Therapy for Rectal Cancer: A Single-center Study of Local Recurrence Patterns.
    Anticancer Res. 2025;45:1261-1271.
    PubMed     Abstract available


  108. GOTO K, Ryu S, Imaizumi Y, Iwauchi S, et al
    Urethral Visualization Using Near-infrared Light Observation During Transanal/Perineal Total Mesorectal Excision.
    Anticancer Res. 2025;45:1241-1249.
    PubMed     Abstract available


  109. SUGIYAMA M, Kasagi Y, Yokomizo R, Terashi M, et al
    Oncologic Relevance and Anal Preservation Potential of Transanal Total Mesorectal Excision for Rectal Cancer Invading Adjacent Organs.
    Anticancer Res. 2025;45:1233-1239.
    PubMed     Abstract available


    February 2025
  110. DREVS J, Malhotra MS, Sahinbas H, Iliopoulos A, et al
    Adjusting Treatment Strategies Using Circulating Tumor Cells: Preliminary Results on Metastatic Colorectal Cancer.
    Anticancer Res. 2025;45:491-502.
    PubMed     Abstract available


  111. YANG IJ, Kim DH, Lee KH, Kim JY, et al
    Safety and Survival Benefit of Adjuvant Chemotherapy for Elderly Patients With Stage II/III Colon Cancer.
    Anticancer Res. 2025;45:797-809.
    PubMed     Abstract available


  112. TAKISHIMA T, Kobayashi Y, Matsukida S, Kai W, et al
    Negative Impact of Low Serum Cholinesterase on Short- and Long-term Outcomes in Elderly Patients Undergoing Scheduled Surgery for Colorectal Cancer.
    Anticancer Res. 2025;45:743-750.
    PubMed     Abstract available


    January 2025
  113. KAWAMURA H, Imaizumi T, Miyakawa T, Nakao E, et al
    Development of a Prognostic Model for Stage IV Colorectal Cancer Using Metastatic Patterns.
    Anticancer Res. 2025;45:341-350.
    PubMed     Abstract available


  114. ZHANG Y, Li X, Li S, Yang Z, et al
    Alternating Oxaliplatin and Irinotecan Chemotherapy Combined With Capecitabine and Bevacizumab for Microsatellite-stable Stage IV Metastatic Colon Cancer With a BRAF V600E Mutation: Two Case Reports Indicating Survival Improvement over Standard Therap
    Anticancer Res. 2025;45:399-404.
    PubMed     Abstract available


  115. KASUGA SO, Nozawa H, Ishihara S
    Changes in Mesorectal CT Values and Therapeutic Effect of Preoperative Chemoradiotherapy in Rectal Cancer.
    Anticancer Res. 2025;45:359-367.
    PubMed     Abstract available


  116. ESKELINEN M, Selander T, Guimaraes DP, Kaarniranta K, et al
    Artificial Intelligence Models Could Enhance the Diagnostic Accuracy (DA) of Fecal Immunochemical Test (FIT) in the Detection of Colorectal Adenoma in a Screening Setting.
    Anticancer Res. 2025;45:267-275.
    PubMed     Abstract available


  117. TSAI YY, Ke TW, Huang CH, Chen TW, et al
    Prognostic Relevance of Immunosuppressive CD155/TIGIT Signaling in Locally Advanced Rectal Cancer Patients With Neoadjuvant Chemoradiotherapy.
    Anticancer Res. 2025;45:323-333.
    PubMed     Abstract available


    December 2024
  118. KIM HB, Choi WY, Kim SH, Lee HJ, et al
    GNAO1: A Novel Tumor Suppressor Gene in Colorectal Cancer Pathogenesis.
    Anticancer Res. 2024;44:5425-5433.
    PubMed     Abstract available


  119. SHIBUTANI M, Kashiwagi S, Tanda H, Seki Y, et al
    Prognostic Significance of Innovative Inflammation-nutrition Biomarker Score in Patients With Colorectal Cancer.
    Anticancer Res. 2024;44:5559-5567.
    PubMed     Abstract available


  120. SHIN H, Kim Y, Lee Y, Kim J, et al
    Chlorhexidine Dihydrochloride Shows Anti-tumor Effects in Desmoid Tumors and Colorectal Cancer.
    Anticancer Res. 2024;44:5435-5443.
    PubMed     Abstract available


  121. LEE Y, Kim Y, Shin H, Ryu YC, et al
    Anti-tumor Effects of Idarubicin Hydrochloride in Desmoid Tumors.
    Anticancer Res. 2024;44:5313-5322.
    PubMed     Abstract available


    November 2024
  122. ZADOROZNYJ A, Karam E, Michot N, Thiery J, et al
    Clinical and Oncological Impact of a Protective Ileostomy in Rectal Cancer Patients Undergoing Adjuvant Chemotherapy.
    Anticancer Res. 2024;44:4995-5005.
    PubMed     Abstract available


  123. NGUYEN MLT, Pham C, Nguyen TS, Nham PLT, et al
    Single-agent Adavosertib Shows Anticancer Effects Against Colorectal Cancer Cells.
    Anticancer Res. 2024;44:4941-4949.
    PubMed     Abstract available


  124. YASUI C, Kono Y, Ishiguro R, Yagyu T, et al
    New Treatment Modalities for Colorectal Cancer Through Simultaneous Suppression of FSP1 and GPX4.
    Anticancer Res. 2024;44:4905-4914.
    PubMed     Abstract available


  125. SUNG YN, Kim Y, Datuin AT, Jang I, et al
    Routine Elastic Staining Helps Detection of Vascular Invasion in Colorectal Cancer: A Comprehensive Analysis of T3 or Higher Tumors Without Lymph Node Metastasis.
    Anticancer Res. 2024;44:5059-5065.
    PubMed     Abstract available


    October 2024
  126. UNRUG-BIELAWSKA K, Earnshaw D, Cybulska-Lubak M, Kaniuga E, et al
    Therapeutic Responses to Two New SN-38 Derivatives in Colorectal Cancer Patient-Derived Xenografts and Respective 3D In Vitro Cultures.
    Anticancer Res. 2024;44:4219-4224.
    PubMed     Abstract available


  127. RUBIO CA, Vieth M, Lang-Schwarz C
    Nondysplastic Colon Crypts Intercalated in Tubular Adenomas Support Field Cancerization.
    Anticancer Res. 2024;44:4371-4377.
    PubMed     Abstract available


  128. HOSIK J, Hosikova B, Kolarova H, Bajgar R, et al
    5,10,15,20-Tetrakis(4-sulfonatophenyl)porphyrin Zinc and Chloro-aluminum Phthalocyanine Disulfonate in Photodynamic Therapy of Colorectal Adenocarcinoma In Vitro.
    Anticancer Res. 2024;44:4339-4346.
    PubMed     Abstract available


  129. VIRGILIO E, Salvemini C, Treglia MG, Thai E, et al
    Hotspots of Anal Cancer Screening in a High-risk Population: A Clinical Study on Free Provision, Best Method, Self-sampling, and Independent Risk Factors.
    Anticancer Res. 2024;44:4465-4481.
    PubMed     Abstract available


    September 2024
  130. HOSOKAWA A, Tamura H, Ichihara A, Imamura N, et al
    Pathological Complete Response to Liver Metastasis With Pembrolizumab in a Previously Treated Patient With Microsatellite Instability-high Colorectal Cancer.
    Anticancer Res. 2024;44:4119-4125.
    PubMed     Abstract available


  131. SHIRAISHI T, Yamaguchi A, Shibasaki Y, Osone K, et al
    Risk Factors of Poor Outcomes After Colorectal Cancer Surgery for Patients With Severe Comorbidities.
    Anticancer Res. 2024;44:4073-4083.
    PubMed     Abstract available


  132. COZZANI F, Ricchiuto M, Virgilio E, Viani L, et al
    The Controlling Nutritional Status (CONUT) Score Predicts Post-operatory Risks and Prognosis in Patients With Surgically Treated Colon Cancer: A Retrospective Study.
    Anticancer Res. 2024;44:3955-3964.
    PubMed     Abstract available


  133. JINNO T, Yamaguchi J, Ogura A, Kokuryo T, et al
    Loss of Trefoil Factor 1 Accelerates the Immune Response to Colorectal Cancer.
    Anticancer Res. 2024;44:3757-3769.
    PubMed     Abstract available


  134. FUKUSHIMA G, Sato E, Udo R, Tago T, et al
    Stromal CD4 (+) T Cell Subsets Mediate Antitumor Cytotoxic Immune Responses in Human Colorectal Carcinoma.
    Anticancer Res. 2024;44:3899-3906.
    PubMed     Abstract available


  135. KAYANO H, Mamuro N, Kamei Y, Ogimi T, et al
    Risk Factors Associated With Perioperative Skeletal Muscle Loss in Patients With Colorectal Cancer.
    Anticancer Res. 2024;44:4019-4029.
    PubMed     Abstract available


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    Simultaneously Detected Liver and Lung Metastases from Colorectal Carcinoma: A Potential Treatment Strategy.
    Anticancer Res. 2024;44:3945-3954.
    PubMed     Abstract available


    August 2024
  137. KAMADA T, Furukawa K, Takahashi J, Aida T, et al
    Preoperative Vertebral Fracture: A Prognostic Factor in Stage I-III Colorectal Cancer.
    Anticancer Res. 2024;44:3533-3541.
    PubMed     Abstract available


  138. YOKOTA Y, Nozawa H, Sonoda H, Yokoyama Y, et al
    Indoleamine 2,3-Dioxygenase Inhibitor Suppresses Colon Cancer Cell Migration, Invasion, and Epithelial-Mesenchymal Transition.
    Anticancer Res. 2024;44:3337-3342.
    PubMed     Abstract available


  139. TSUJIO G, Fukuoka T, Sugimoto A, Yonemitsu K, et al
    The Efficacy of Chemical Bowel Preparation Against Incisional Surgical Site Infection in Colorectal Cancer Surgery: A Propensity Score Matching Study.
    Anticancer Res. 2024;44:3473-3480.
    PubMed     Abstract available


  140. FUKUDA J, Sudo T, Kikuchi M, Kawahara A, et al
    Identification of DNA Repair-related Genes as Biomarkers Reflecting MSI, TMB, and TIL in Colorectal Cancer.
    Anticancer Res. 2024;44:3567-3575.
    PubMed     Abstract available


  141. TAKAHASHI H, Kojima D, Wada H, Hanaoka K, et al
    A Bridge to Curative Surgery for Obstructive Colorectal Cancer: Self-expandable Metallic Stent Versus Decompression Tube.
    Anticancer Res. 2024;44:3427-3441.
    PubMed     Abstract available


  142. MUKOHYAMA J, Koizumi M, Yamashita K, Yoshimi A, et al
    Knockdown of CDX2 Induces microRNA-221 Up-regulation in Human Colon Cancer Cells.
    Anticancer Res. 2024;44:3553-3556.
    PubMed     Abstract available


    July 2024
  143. KOMORI K, Yoshida M, Tsukushi S, Kinoshita T, et al
    Combined Pubic Arch and Ischial Bone Resection for Metachronous and Frequent Local Recurrences of Rectal Cancer.
    Anticancer Res. 2024;44:3205-3211.
    PubMed     Abstract available


  144. LEE SH, Kim SA, Park SJ, Lee MY, et al
    NUAK2 Inhibitors, KHKI-01128 and KHKI-01215, Exhibit Potent Anticancer Activity Against SW480 Colorectal Cancer Cells.
    Anticancer Res. 2024;44:2909-2919.
    PubMed     Abstract available


  145. SHIOI I, Ogawa H, Naito R, Endo M, et al
    Risks and Outcomes of Early Dose Reduction in Adjuvant CAPOX Therapy for Colorectal Cancer.
    Anticancer Res. 2024;44:3013-3023.
    PubMed     Abstract available


  146. TSUMURAYA H, Mimura K, Nakajima S, Hanayama H, et al
    Tumor Infiltrating Effector Regulatory T Cells Express VEGF Receptor 2 in Patients With Colorectal Cancer.
    Anticancer Res. 2024;44:2933-2941.
    PubMed     Abstract available


  147. KARLIKOVA M, Curillova M, Pecen L, Karnos V Jr, et al
    Evaluation of Serum Cytokeratines, Thymidine Kinase, and Growth Factors as Cancer Biomarkers in Colorectal Cancer.
    Anticancer Res. 2024;44:3105-3113.
    PubMed     Abstract available


    June 2024
  148. MOON SU, Lee JH, Shah M, Yoon S, et al
    RRM2 Is a CTNNB1 Transport Regulator Promoting Colon Cancer Progression.
    Anticancer Res. 2024;44:2471-2485.
    PubMed     Abstract available


  149. TOREN W, Sasor A, Ansari D, Andersson R, et al
    ARHGAP4 as a Prognostic Biomarker for Colon Liver Metastases After Surgical Resection.
    Anticancer Res. 2024;44:2597-2604.
    PubMed     Abstract available


  150. MATSUDA A, Yamada T, Takahashi G, Matsumoto S, et al
    Significance of Adjuvant Chemotherapy for Obstructive Colorectal Cancer After Stent Placement: A Multicenter Retrospective Study.
    Anticancer Res. 2024;44:2737-2745.
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  151. LIM SC, Lee TB, Han SI
    Caffeic Acid Enhances Anticancer Drug-induced Apoptosis in Acid-adapted HCT116 Colon Cancer Cells.
    Anticancer Res. 2024;44:2587-2595.
    PubMed     Abstract available


    May 2024
  152. WAGNER D, Karitnig R, Wienerroither V, Hau HM, et al
    Sarcopenic Obesity Promotes Recurrence in Patients Undergoing Resection for Colorectal Liver Metastases (CRLM).
    Anticancer Res. 2024;44:2177-2183.
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    April 2024
  153. WU CC, Su CC, Chen YH, Hsu CW, et al
    Comparative Effectiveness of Adjuvant Therapy on Survival in Patients With Metastatic Colorectal Cancer.
    Anticancer Res. 2024;44:1619-1628.
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  154. TANAKA H, Hayashi H, Tomita H, Tokumaru Y, et al
    Association of Preoperative and Postoperative Plasma Syndecan-1 and Colorectal Cancer Outcome.
    Anticancer Res. 2024;44:1611-1618.
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  155. SHIRAISHI T, Tominaga T, Ono R, Noda K, et al
    Short- and Long-term Outcomes After Colonic Stent Insertion as a Bridge to Surgery in Elderly Colorectal Cancer Patients.
    Anticancer Res. 2024;44:1637-1643.
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  156. SYRJANEN K, Eskelinen M, Meklin J, Hendolin P, et al
    Colorectal Cancer Screening by Fecal Immunochemical Tests (FIT): Considerations on Sampling and Markers (Hb and Hb/Hp Complex) of Fecal Occult Blood (FOB).
    Anticancer Res. 2024;44:1513-1523.
    PubMed     Abstract available


  157. BEPPU T, Yamamura K, Masuda T, Miyamoto H, et al
    High-risk Patients With Colorectal Liver Metastases Assessed by the Beppu Score Can Have Excellent Survival Through Multidisciplinary Treatment Including Local Ablation.
    Anticancer Res. 2024;44:1533-1539.
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  158. SATOYOSHI T, Hirohashi Y, Okuya K, Miyo M, et al
    CD8-positive T Cell Infiltration With Human Leukocyte Antigen Class 1 Expression Predicts Patients With Stage IV Colorectal Cancer Survival.
    Anticancer Res. 2024;44:1603-1610.
    PubMed     Abstract available


  159. AOYAMA T, Yukawa N, Saito A
    Clinical Impact of Nutrition and Inflammation Assessment Tools in Colorectal Cancer Treatment.
    Anticancer Res. 2024;44:1335-1351.
    PubMed     Abstract available


    March 2024
  160. ZHENG W, Chen K, Lv Y, Lao W, et al
    Pyrvinium Pamoate Induces Cell Apoptosis and Autophagy in Colorectal Cancer.
    Anticancer Res. 2024;44:1193-1199.
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  161. EBATA Y, Nakanishi R, Tanaka Y, Kawazoe T, et al
    Neoadjuvant Chemotherapy in Patients With T4b or Obstructive Colon Cancer: A Single Center Retrospective Cohort Study.
    Anticancer Res. 2024;44:1281-1287.
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  162. HARA S, Sakai D, Ikemura K, Shintani T, et al
    Comparative Efficacy and Safety of Standard and Biweekly Trifluridine/Tipiracil Regimen in Patients With Colorectal Cancer.
    Anticancer Res. 2024;44:1219-1226.
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  163. SILVA EF, Fernandes BN, Marinello P, Deminice R, et al
    Pre and Post-high-intensity Interval Training Delays Colon Tumor Onset in a Syngeneic Mouse Model.
    Anticancer Res. 2024;44:1209-1217.
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  164. HEGEDUS D, Szemeredi N, Gabor M, Sas J, et al
    Cyclic Amines Coupled to Indole Derivatives With Improved Efflux Pump Inhibiting Activity in Bacteria and Cancer Cells.
    Anticancer Res. 2024;44:1149-1160.
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  165. ARDJMAND D, Kubota Y, Sato M, Han Q, et al
    Selective Synergy of Rapamycin Combined With Methioninase on Cancer Cells Compared to Normal Cells.
    Anticancer Res. 2024;44:929-933.
    PubMed     Abstract available


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