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  Colorectal Neoplasms

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Articles published in Br J Cancer

Retrieve available abstracts of 70 articles:
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Single Articles


    October 2025
  1. CHANG YH, Bresnahan ST, Taylor Head S, Harrison TA, et al
    Isoform-level analyses of 6 cancers uncover extensive genetic risk mechanisms undetected at the gene-level.
    Br J Cancer. 2025;133:874-885.
    PubMed     Abstract available


  2. THONG MSY, Doege D, Koch-Gallenkamp L, Bertram H, et al
    Fatigue in long-term cancer survivors: prevalence, associated factors, and mortality. A prospective population-based study.
    Br J Cancer. 2025;133:831-843.
    PubMed     Abstract available


  3. YU H, Jin S, Zeng M, Yang Z, et al
    TIGIT antibody with PVR competitive ability enhances cancer immunotherapy and capable of eliciting anti-tumour immune memory.
    Br J Cancer. 2025;133:743-755.
    PubMed     Abstract available


    September 2025
  4. KAWAMURA H, Honda M, Nakayama Y, Oba K, et al
    Adverse events of postoperative adjuvant chemotherapy predict survival outcomes in locally advanced colorectal cancer: a pooled analysis of Japanese clinical trials.
    Br J Cancer. 2025 Sep 22. doi: 10.1038/s41416-025-03199.
    PubMed     Abstract available


  5. FENG Y, Zhu J, Ou C, Deng Z, et al
    Retraction Note: MicroRNA-145 inhibits tumour growth and metastasis in colorectal cancer by targeting fascin-1.
    Br J Cancer. 2025 Sep 19. doi: 10.1038/s41416-025-03209.
    PubMed    


  6. MONTERO-CALLE A, Jimenez de Ocana S, Rejas-Gonzalez R, Benavente-Naranjo R, et al
    Deciphering the central role of TMOD2 in colorectal cancer progression and metastasis.
    Br J Cancer. 2025 Sep 17. doi: 10.1038/s41416-025-03184.
    PubMed     Abstract available


    August 2025
  7. BALLHAUSEN A, Morano F, Stahler A, Lonardi S, et al
    Primary tumor sidedness and negative hyperselection to modulate anti-EGFR-based maintenance strategies in patients with RAS wild-type metastatic colorectal cancer: individual patient data pooled analysis of two randomized clinical trials.
    Br J Cancer. 2025 Aug 28. doi: 10.1038/s41416-025-03164.
    PubMed     Abstract available


  8. BARLOW M, Messenger D, Preece R, Prowse A, et al
    The diagnostic accuracy of the faecal immunochemical test for the detection of early-onset colorectal cancer: an age-stratified analysis in South West England.
    Br J Cancer. 2025 Aug 22. doi: 10.1038/s41416-025-03154.
    PubMed     Abstract available


  9. ZHANG D, Yang S, Xu H, Chen Z, et al
    The novel role of DUSP4 in suppressing ferroptosis and promoting cytotoxicity of CD8(+) T cells in MSI colorectal cancer.
    Br J Cancer. 2025 Aug 22. doi: 10.1038/s41416-025-03119.
    PubMed     Abstract available


  10. GALMARINI CM, Zamora R, Gomez Del Campo P, Del Castillo-Izquierdo J, et al
    PROCC: a predictive score to identify KRAS wild type metastatic colorectal cancer patients who are likely to obtain survival benefit from panitumumab treatment.
    Br J Cancer. 2025 Aug 20. doi: 10.1038/s41416-025-03157.
    PubMed     Abstract available


  11. TOH Y, Wu L, Tu J, Liang Z, et al
    Anti-tumor activity of camptothecin analog conjugate of an RSPO4-based peptibody targeting LGR4/5/6 in preclinical models of colorectal cancer.
    Br J Cancer. 2025 Aug 18. doi: 10.1038/s41416-025-03121.
    PubMed     Abstract available


    July 2025
  12. SHENG Y, Yan L, Liu Q, Peng Y, et al
    The pronounced cytotoxic effects of chimeric antigen receptor T cells targeting B7-H3 in organoids and liver xenografts derived from colorectal cancer patients.
    Br J Cancer. 2025 Jul 28. doi: 10.1038/s41416-025-03114.
    PubMed     Abstract available


  13. YU L, Guo Q, Gu X, Wang Z, et al
    Impact of gut microbiome on radiotherapy and immunotherapy efficacy in microsatellite-stable colorectal cancer: role of propionic acid and B. fragilis.
    Br J Cancer. 2025 Jul 26. doi: 10.1038/s41416-025-03105.
    PubMed     Abstract available


  14. ZHANG J, Xiao Z, Lai D, Sun J, et al
    Retraction Note: miR-21, miR-17 and miR-19a induced by phosphatase of regenerating liver-3 promote the proliferation and metastasis of colon cancer.
    Br J Cancer. 2025 Jul 25. doi: 10.1038/s41416-025-03135.
    PubMed    


  15. ZHANG J, Dong H, Liang L, Hu L, et al
    Targeting gut microbiota and arginase boosts MEK inhibitors' enhancement of antitumour immunity via MHC-I upregulation in colorectal cancer.
    Br J Cancer. 2025 Jul 17. doi: 10.1038/s41416-025-03106.
    PubMed     Abstract available


  16. SEO JW, Kim JY, Ha YJ, Tak KH, et al
    Prognostic and therapeutic value of a 23-gene risk score tailored to the molecular characteristics of mucinous colorectal cancer.
    Br J Cancer. 2025 Jul 2. doi: 10.1038/s41416-025-03104.
    PubMed     Abstract available


    June 2025
  17. MESA-EGUIAGARAY I, Iakovliev A, Li X, Timofeeva M, et al
    Association between methylation quantitative trait loci and colorectal cancer risk, survival and cancer recurrence.
    Br J Cancer. 2025 Jun 12. doi: 10.1038/s41416-025-03064.
    PubMed     Abstract available


  18. ZHONG W, Zhang Y, Wang W, Shao Z, et al
    TRIM26 deficiency potentially suppresses colorectal cancer liver metastasis through NF-kappaB-mediated M1-like tumor-associated macrophage polarization.
    Br J Cancer. 2025 Jun 9. doi: 10.1038/s41416-025-03072.
    PubMed     Abstract available


  19. RUBIO-CUESTA B, Carretero-Puche C, Llamas P, Sarmentero J, et al
    Co-targeting SRC overcomes resistance to BRAF inhibitors in colorectal cancer.
    Br J Cancer. 2025 Jun 6. doi: 10.1038/s41416-025-03058.
    PubMed     Abstract available


  20. ANDEL D, Nouwens AJ, Klaassen S, Laoukili J, et al
    Rational design of alternative treatment options for radioresistant rectal cancer using patient-derived organoids.
    Br J Cancer. 2025;132:973-981.
    PubMed     Abstract available


    April 2025
  21. YUAN F, Jia G, Wen W, Xu S, et al
    Blood metabolic biomarkers and colorectal cancer risk: results from large prospective cohort and Mendelian randomisation analyses.
    Br J Cancer. 2025 Apr 30. doi: 10.1038/s41416-025-02997.
    PubMed     Abstract available


  22. REITSAM NG, Markl B
    Stroma AReactive Invasion Front Areas (SARIFA) and the tumour immune microenvironment in colorectal cancer.
    Br J Cancer. 2025 Apr 26. doi: 10.1038/s41416-025-03034.
    PubMed    


  23. LEE HJ, Park SW, Lee JH, Chang SY, et al
    Correction: Differential cellular origins of the extracellular matrix of tumor and normal tissues according to colorectal cancer subtypes.
    Br J Cancer. 2025 Apr 11. doi: 10.1038/s41416-025-02988.
    PubMed    


  24. HASJIM BJ, Ostowari A, Gandawidjaja M, Mohammadi MD, et al
    De novo colorectal cancer after kidney transplantation: a systematic review and meta-analysis.
    Br J Cancer. 2025 Apr 5. doi: 10.1038/s41416-025-02994.
    PubMed     Abstract available


  25. ELOMAA H, Tarkiainen V, Aijala VK, Sirnio P, et al
    Associations of mucinous differentiation and mucin expression with immune cell infiltration and prognosis in colorectal adenocarcinoma.
    Br J Cancer. 2025;132:660-669.
    PubMed     Abstract available


    March 2025
  26. GRANCHER A, Beaussire-Trouvay L, Vernon V, Dutherage M, et al
    ctDNA variations according to treatment intensity in first-line metastatic colorectal cancer.
    Br J Cancer. 2025 Mar 15. doi: 10.1038/s41416-025-02971.
    PubMed     Abstract available


  27. TANG F, Zhu Y, Shen J, Yuan B, et al
    CD44(+) cells enhance pro-tumor stroma in the spatial landscape of colorectal cancer leading edge.
    Br J Cancer. 2025 Mar 12. doi: 10.1038/s41416-025-02968.
    PubMed     Abstract available


  28. TAPIAINEN VV, Sirnio P, Elomaa H, Karjalainen H, et al
    Stroma AReactive Invasion Front Areas (SARIFA), tumour immune microenvironment, and survival in colorectal cancer.
    Br J Cancer. 2025 Mar 7. doi: 10.1038/s41416-025-02972.
    PubMed     Abstract available


  29. LEE HJ, Park SW, Lee JH, Chang SY, et al
    Differential cellular origins of the extracellular matrix of tumor and normal tissues according to colorectal cancer subtypes.
    Br J Cancer. 2025 Mar 3. doi: 10.1038/s41416-025-02964.
    PubMed     Abstract available


    February 2025
  30. ZHANG Y, Wu D, Zhang Z, Ma J, et al
    Correction: Impact of lymph node metastasis on immune microenvironment and prognosis in colorectal cancer liver metastasis: insights from multiomics profiling.
    Br J Cancer. 2025 Feb 17. doi: 10.1038/s41416-025-02941.
    PubMed    


  31. BUNDRED J, Lal N, Chan DKH, Buczacki SJA, et al
    Lymph node yield as a surrogate marker for tumour biology and prognosis in colon cancer.
    Br J Cancer. 2025 Feb 14. doi: 10.1038/s41416-025-02949.
    PubMed     Abstract available


  32. KATO Y, Seishima R, Hattori K, Kato H, et al
    Significance of homologous recombinant deficiency as a biomarker for drug sensitivity in colorectal cancer.
    Br J Cancer. 2025 Feb 11. doi: 10.1038/s41416-025-02950.
    PubMed     Abstract available


    January 2025
  33. ZHANG Y, Wu D, Zhang Z, Ma J, et al
    Impact of lymph node metastasis on immune microenvironment and prognosis in colorectal cancer liver metastasis: insights from multiomics profiling.
    Br J Cancer. 2025 Jan 3. doi: 10.1038/s41416-024-02921.
    PubMed     Abstract available


    December 2024
  34. LIU C, Reger M, Fan H, Wang J, et al
    Dietary intake of isoflavones and coumestrol and risk of pancreatic cancer in the prostate, lung, colorectal, and ovarian cancer screening trial.
    Br J Cancer. 2024 Dec 16. doi: 10.1038/s41416-024-02929.
    PubMed     Abstract available


    November 2024
  35. PRETTA A, Ziranu P, Perissinotto E, Ghelardi F, et al
    Early onset metastatic colorectal cancer patients as a distinctive clinical and molecular phenomenon.
    Br J Cancer. 2024 Nov 27. doi: 10.1038/s41416-024-02902.
    PubMed     Abstract available


  36. CHAN WC, Liu L, Bouras E, Zuber V, et al
    Associations of blood lipids and LDL cholesterol lowering drug-targets with colorectal cancer risk: a Mendelian randomisation study.
    Br J Cancer. 2024 Nov 23. doi: 10.1038/s41416-024-02900.
    PubMed     Abstract available


  37. POGHOSYAN S, Frenkel N, van den Bent L, Raats D, et al
    VEGF-C propagates 'onward' colorectal cancer metastasis from liver to lung.
    Br J Cancer. 2024 Nov 9. doi: 10.1038/s41416-024-02892.
    PubMed     Abstract available


  38. CAMPOS GUDINO R, Neudorf NM, Andromidas D, Lichtensztejn Z, et al
    Loss of EMI1 compromises chromosome stability and is associated with cellular transformation in colonic epithelial cell contexts.
    Br J Cancer. 2024;131:1516-1528.
    PubMed     Abstract available


    October 2024
  39. LI B, Yang W, Liu N, Bi D, et al
    Phase II Study of Irinotecan, Trifluridine/tipiracil (TAS-102) plus Bevacizumab as a Later-line Therapy for Patients with Metastatic Colorectal Cancer (mCRC): a prospective single-center explorative study.
    Br J Cancer. 2024 Oct 24. doi: 10.1038/s41416-024-02885.
    PubMed     Abstract available


  40. OGAARD N, Jensen SO, Orntoft MW, Demuth C, et al
    Circulating tumour DNA and risk of recurrence in patients with asymptomatic versus symptomatic colorectal cancer.
    Br J Cancer. 2024 Oct 10. doi: 10.1038/s41416-024-02867.
    PubMed     Abstract available


  41. NOH H, Lee J, Seyed Khoei N, Peruchet-Noray L, et al
    Serum bilirubin levels and risk of colorectal cancer in Korean adults: results from the Korean Genome and Epidemiology Study-Health Examinee (KoGES-HEXA) Cohort Study.
    Br J Cancer. 2024 Oct 8. doi: 10.1038/s41416-024-02847.
    PubMed     Abstract available


  42. SEKHAR H, Kochhar R, Carrington B, Kaye T, et al
    Pre-treatment magnetic resonance imaging in anal cancer: large-scale evaluation of mrT, mrN and novel staging parameters.
    Br J Cancer. 2024;131:1137-1146.
    PubMed     Abstract available


    September 2024
  43. AMODIO V, Vitiello PP, Bardelli A, Germano G, et al
    DNA repair-dependent immunogenic liabilities in colorectal cancer: opportunities from errors.
    Br J Cancer. 2024 Sep 13. doi: 10.1038/s41416-024-02848.
    PubMed     Abstract available


  44. BOLAND PM, Mukherjee S, Imanirad I, Vijayvergia N, et al
    TAS-102, Irinotecan, and bevacizumab in pre-treated metastatic colorectal cancer (TABAsCO), a phase II clinical trial.
    Br J Cancer. 2024 Sep 7. doi: 10.1038/s41416-024-02845.
    PubMed     Abstract available


  45. CHOWDHURY S, Xiu J, Ribeiro JR, Nicolaides T, et al
    Consensus molecular subtyping of metastatic colorectal cancer expands biomarker-directed therapeutic benefit for patients with CMS1 and CMS2 tumors.
    Br J Cancer. 2024 Sep 4. doi: 10.1038/s41416-024-02826.
    PubMed     Abstract available


    August 2024
  46. GWENZI T, Schrotz-King P, Anker SC, Schottker B, et al
    Prognostic value of post-operative iron biomarkers in colorectal cancer: population-based patient cohort.
    Br J Cancer. 2024 Aug 27. doi: 10.1038/s41416-024-02814.
    PubMed     Abstract available


    July 2024
  47. SEGAL NH, Tie J, Kopetz S, Ducreux M, et al
    COLUMBIA-1: a randomised study of durvalumab plus oleclumab in combination with chemotherapy and bevacizumab in metastatic microsatellite-stable colorectal cancer.
    Br J Cancer. 2024 Jul 25. doi: 10.1038/s41416-024-02796.
    PubMed     Abstract available


  48. LAWLER T, Hibler E, Walts ZL, Giurini L, et al
    Associations of diabetes and mortality among colorectal cancer patients from the Southern Community Cohort Study.
    Br J Cancer. 2024 Jul 19. doi: 10.1038/s41416-024-02787.
    PubMed     Abstract available


  49. HOU P, Shi P, Jiang T, Yin H, et al
    Correction: DKC1 enhances angiogenesis by promoting HIF-1alpha transcription and facilitates metastasis in colorectal cancer.
    Br J Cancer. 2024 Jul 17. doi: 10.1038/s41416-024-02801.
    PubMed    


  50. MASUI H, Kawada K, Itatani Y, Hirai H, et al
    Synergistic antitumor activity by dual blockade of CCR1 and CXCR2 expressed on myeloid cells within the tumor microenvironment.
    Br J Cancer. 2024;131:63-76.
    PubMed     Abstract available


  51. TSUKADA Y, Bando H, Inamori K, Wakabayashi M, et al
    Three-year outcomes of preoperative chemoradiotherapy plus nivolumab in microsatellite stable and microsatellite instability-high locally advanced rectal cancer.
    Br J Cancer. 2024;131:283-289.
    PubMed     Abstract available


    June 2024
  52. YANG L, Yi J, He W, Kong P, et al
    Correction: Death receptors 4/5 mediate tumour sensitivity to natural killer cell-mediated cytotoxicity in mismatch repair deficient colorectal cancer.
    Br J Cancer. 2024 Jun 26. doi: 10.1038/s41416-024-02768.
    PubMed    


  53. EXARCHAKOU A, Rachet B, Lyratzopoulos G, Maringe C, et al
    What can hospital emergency admissions prior to cancer diagnosis tell us about socio-economic inequalities in cancer diagnosis? Evidence from population-based data in England.
    Br J Cancer. 2024;130:1960-1968.
    PubMed     Abstract available


    May 2024
  54. YANG L, Yi J, He W, Kong P, et al
    Death receptors 4/5 mediate tumour sensitivitNot applicably to natural killer cell-mediated cytotoxicity in mismatch repair deficient colorectal cancer.
    Br J Cancer. 2024 May 25. doi: 10.1038/s41416-024-02673.
    PubMed     Abstract available


  55. ZWART K, van Nassau SCMW, van der Baan FH, Koopman M, et al
    Efficacy-effectiveness analysis on survival in a population-based real-world study of BRAF-mutated metastatic colorectal cancer patients treated with encorafenib-cetuximab.
    Br J Cancer. 2024 May 20. doi: 10.1038/s41416-024-02711.
    PubMed     Abstract available


  56. VILLAREAL LB, Falcon DM, Xie L, Xue X, et al
    Hypoxia-inducible factor 3alpha1 increases epithelial-to-mesenchymal transition and iron uptake to drive colorectal cancer liver metastasis.
    Br J Cancer. 2024 May 1. doi: 10.1038/s41416-024-02699.
    PubMed     Abstract available


  57. QIAO L, Liu Y, Yang Q
    Comment on: "Neoadjuvant chemotherapy is noninferior to chemoradiotherapy for early-onset locally advanced rectal cancer in the FOWARC trial".
    Br J Cancer. 2024;130:1432-1433.
    PubMed    


  58. CAI J, Lin K, Luo T, Weng J, et al
    Neoadjuvant chemotherapy is noninferior to chemoradiotherapy for early-onset locally advanced rectal cancer in the FOWARC trial.
    Br J Cancer. 2024;130:1434-1440.
    PubMed     Abstract available


  59. MENG XN, Ma JF, Liu YH, Li SQ, et al
    Dynamic genomic changes in methotrexate-resistant human cancer cell lines beyond DHFR amplification suggest potential new targets for preventing drug resistance.
    Br J Cancer. 2024;130:1819-1827.
    PubMed     Abstract available


  60. KISAKOL B, Matveeva A, Salvucci M, Kel A, et al
    Identification of unique rectal cancer-specific subtypes.
    Br J Cancer. 2024;130:1809-1818.
    PubMed     Abstract available


    April 2024
  61. REE AH, Saltyte Benth J, Hamre HM, Kersten C, et al
    First-line oxaliplatin-based chemotherapy and nivolumab for metastatic microsatellite-stable colorectal cancer-the randomised METIMMOX trial.
    Br J Cancer. 2024 Apr 25. doi: 10.1038/s41416-024-02696.
    PubMed     Abstract available


  62. RIO-VILARINO A, Cenigaonandia-Campillo A, Garcia-Bautista A, Mateos-Gomez PA, et al
    Correction: Inhibition of the AURKA/YAP1 axis is a promising therapeutic option for overcoming cetuximab resistance in colorectal cancer stem cells.
    Br J Cancer. 2024 Apr 4. doi: 10.1038/s41416-024-02667.
    PubMed    


  63. BARANYI M, Molnar E, Hegedus L, Gabriel Z, et al
    Farnesyl-transferase inhibitors show synergistic anticancer effects in combination with novel KRAS-G12C inhibitors.
    Br J Cancer. 2024;130:1059-1072.
    PubMed     Abstract available


  64. TIAN Y, Lin Y, Qu C, Arndt V, et al
    Genetic risk impacts the association of menopausal hormone therapy with colorectal cancer risk.
    Br J Cancer. 2024 Apr 1. doi: 10.1038/s41416-024-02638.
    PubMed     Abstract available


    March 2024
  65. FELIU J, Gamez-Pozo A, Martinez-Perez D, Perez-Wert P, et al
    Functional proteomics of colon cancer Consensus Molecular Subtypes.
    Br J Cancer. 2024 Mar 14. doi: 10.1038/s41416-024-02650.
    PubMed     Abstract available


  66. ZHANG X, He Y, Li X, Shraim R, et al
    Circulating 25-hydroxyvitamin D and survival outcomes of colorectal cancer: evidence from population-based prospective cohorts and Mendelian randomisation.
    Br J Cancer. 2024 Mar 13. doi: 10.1038/s41416-024-02643.
    PubMed     Abstract available


  67. RIO-VILARINO A, Cenigaonandia-Campillo A, Garcia-Bautista A, Mateos-Gomez PA, et al
    Inhibition of the AURKA/YAP1 axis is a promising therapeutic option for overcoming cetuximab resistance in colorectal cancer stem cells.
    Br J Cancer. 2024 Mar 11. doi: 10.1038/s41416-024-02649.
    PubMed     Abstract available


  68. DENG LQ, Shi CJ, Zhou ST, Zeng WQ, et al
    EIF4A3-negatively driven circular RNA beta-catenin (circbeta-catenin) promotes colorectal cancer progression via miR-197-3p/CTNND1 regulatory axis.
    Br J Cancer. 2024 Mar 8. doi: 10.1038/s41416-024-02612.
    PubMed     Abstract available


  69. GOURIOU C, Lemanski C, Pommier P, Le Malicot K, et al
    Management of non-metastatic anal cancer in the elderly: ancillary study of the French multicenter prospective cohort FFCD-ANABASE.
    Br J Cancer. 2024;130:769-776.
    PubMed     Abstract available


    February 2024
  70. KARAPETIS CS, Liu H, Sorich MJ, Pederson LD, et al
    Fluoropyrimidine type, patient age, tumour sidedness and mutation status as determinants of benefit in patients with metastatic colorectal cancer treated with EGFR monoclonal antibodies: individual patient data pooled analysis of randomised trials fro
    Br J Cancer. 2024 Feb 24. doi: 10.1038/s41416-024-02604.
    PubMed     Abstract available


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