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COVID Reference, 5th edition, 486 pages

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Articles published in Br J Cancer

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Single Articles


    November 2020
  1. JACOME AA, Vreeland TJ, Johnson B, Kawaguchi Y, et al
    The prognostic impact of RAS on overall survival following liver resection in early versus late-onset colorectal cancer patients.
    Br J Cancer. 2020 Nov 19. pii: 10.1038/s41416-020-01169.
    PubMed     Abstract available


  2. HUIJBERTS SCFA, Boelens MC, Bernards R, Opdam FL, et al
    Mutational profiles associated with resistance in patients with BRAFV600E mutant colorectal cancer treated with cetuximab and encorafenib +/- binimetinib or alpelisib.
    Br J Cancer. 2020 Nov 18. pii: 10.1038/s41416-020-01147.
    PubMed     Abstract available


  3. HEINEMANN V, von Weikersthal LF, Decker T, Kiani A, et al
    FOLFIRI plus cetuximab or bevacizumab for advanced colorectal cancer: final survival and per-protocol analysis of FIRE-3, a randomised clinical trial.
    Br J Cancer. 2020 Nov 6. pii: 10.1038/s41416-020-01140.
    PubMed     Abstract available


  4. FANG Z, He M, Song M
    Serum lipid profiles and risk of colorectal cancer: a prospective cohort study in the UK Biobank.
    Br J Cancer. 2020 Nov 3. pii: 10.1038/s41416-020-01143.
    PubMed     Abstract available


    October 2020
  5. CHA PH, Hwang JH, Kwak DK, Koh E, et al
    APC loss induces Warburg effect via increased PKM2 transcription in colorectal cancer.
    Br J Cancer. 2020 Oct 19. pii: 10.1038/s41416-020-01118.
    PubMed     Abstract available


  6. WENSINK GE, Elferink MAG, May AM, Mol L, et al
    Survival of patients with deficient mismatch repair metastatic colorectal cancer in the pre-immunotherapy era.
    Br J Cancer. 2020 Oct 13. pii: 10.1038/s41416-020-01076.
    PubMed     Abstract available


  7. ROSSINI D, Lonardi S, Antoniotti C, Santini D, et al
    Treatments after progression to first-line FOLFOXIRI and bevacizumab in metastatic colorectal cancer: a pooled analysis of TRIBE and TRIBE2 studies by GONO.
    Br J Cancer. 2020 Oct 7. pii: 10.1038/s41416-020-01089.
    PubMed     Abstract available


    September 2020
  8. SIMIN J, Fornes R, Liu Q, Olsen RS, et al
    Antibiotic use and risk of colorectal cancer: a systematic review and dose-response meta-analysis.
    Br J Cancer. 2020 Sep 24. pii: 10.1038/s41416-020-01082.
    PubMed     Abstract available


  9. VAUGHAN-SHAW PG, Buijs LF, Blackmur JP, Theodoratou E, et al
    The effect of vitamin D supplementation on survival in patients with colorectal cancer: systematic review and meta-analysis of randomised controlled trials.
    Br J Cancer. 2020 Sep 15. pii: 10.1038/s41416-020-01060.
    PubMed     Abstract available


    August 2020
  10. MASUISHI T, Tsuji A, Kotaka M, Nakamura M, et al
    Phase 2 study of irinotecan plus cetuximab rechallenge as third-line treatment in KRAS wild-type metastatic colorectal cancer: JACCRO CC-08.
    Br J Cancer. 2020 Aug 31. pii: 10.1038/s41416-020-01042.
    PubMed     Abstract available


  11. COWLING TE, Bellot A, Boyle J, Walker K, et al
    One-year mortality of colorectal cancer patients: development and validation of a prediction model using linked national electronic data.
    Br J Cancer. 2020 Aug 24. pii: 10.1038/s41416-020-01034.
    PubMed     Abstract available


  12. KIM TW, Lee YS, Yun NH, Shin CH, et al
    Correction: MicroRNA-17-5p regulates EMT by targeting vimentin in colorectal cancer.
    Br J Cancer. 2020 Aug 20. pii: 10.1038/s41416-020-1027.
    PubMed     Abstract available


    July 2020
  13. RAGHAV K, Shen JP, Jacome AA, Guerra JL, et al
    Integrated clinico-molecular profiling of appendiceal adenocarcinoma reveals a unique grade-driven entity distinct from colorectal cancer.
    Br J Cancer. 2020 Jul 31. pii: 10.1038/s41416-020-1015.
    PubMed     Abstract available


  14. CRAIG SG, Humphries MP, Alderdice M, Bingham V, et al
    Immune status is prognostic for poor survival in colorectal cancer patients and is associated with tumour hypoxia.
    Br J Cancer. 2020 Jul 20. pii: 10.1038/s41416-020-0985.
    PubMed     Abstract available


  15. YANG L, Chen P, Zhang L, Wang L, et al
    Prognostic value of nucleotyping, DNA ploidy and stroma in high-risk stage II colon cancer.
    Br J Cancer. 2020 Jul 6. pii: 10.1038/s41416-020-0974.
    PubMed     Abstract available


  16. YUAN C, Ng K
    Vitamin D supplementation: a potential therapeutic agent for metastatic colorectal cancer.
    Br J Cancer. 2020 Jul 6. pii: 10.1038/s41416-020-0958.
    PubMed     Abstract available


    June 2020
  17. IWAMOTO K, Takahashi H, Okuzaki D, Osawa H, et al
    Syntenin-1 promotes colorectal cancer stem cell expansion and chemoresistance by regulating prostaglandin E2 receptor.
    Br J Cancer. 2020 Jun 29. pii: 10.1038/s41416-020-0965.
    PubMed     Abstract available


  18. KIM TW, Lee YS, Yun NH, Shin CH, et al
    MicroRNA-17-5p regulates EMT by targeting vimentin in colorectal cancer.
    Br J Cancer. 2020 Jun 17. pii: 10.1038/s41416-020-0940.
    PubMed     Abstract available


  19. BABIC A, Zhang X, Morales-Oyarvide V, Yuan C, et al
    Acid-suppressive medications and risk of colorectal cancer: results from three large prospective cohort studies.
    Br J Cancer. 2020 Jun 16. pii: 10.1038/s41416-020-0939.
    PubMed     Abstract available


  20. PERNOT S, Pellerin O, Artru P, Monterymard C, et al
    Intra-arterial hepatic beads loaded with irinotecan (DEBIRI) with mFOLFOX6 in unresectable liver metastases from colorectal cancer: a Phase 2 study.
    Br J Cancer. 2020 Jun 8. pii: 10.1038/s41416-020-0917.
    PubMed     Abstract available


  21. PARK JW, Chang HJ, Yeo HY, Han N, et al
    The relationships between systemic cytokine profiles and inflammatory markers in colorectal cancer and the prognostic significance of these parameters.
    Br J Cancer. 2020 Jun 3. pii: 10.1038/s41416-020-0924.
    PubMed     Abstract available


    May 2020
  22. RAY AL, Nofchissey RA, Khan MA, Reidy MA, et al
    The role of sex in the innate and adaptive immune environment of metastatic colorectal cancer.
    Br J Cancer. 2020 May 26. pii: 10.1038/s41416-020-0913.
    PubMed     Abstract available


  23. WANG K, Song K, Ma Z, Yao Y, et al
    Identification of EMT-related high-risk stage II colorectal cancer and characterisation of metastasis-related genes.
    Br J Cancer. 2020 May 21. pii: 10.1038/s41416-020-0902.
    PubMed     Abstract available


  24. FUCA G, Guarini V, Antoniotti C, Morano F, et al
    The Pan-Immune-Inflammation Value is a new prognostic biomarker in metastatic colorectal cancer: results from a pooled-analysis of the Valentino and TRIBE first-line trials.
    Br J Cancer. 2020 May 19. pii: 10.1038/s41416-020-0894.
    PubMed     Abstract available


  25. LOKTIONOV A, Soubieres A, Bandaletova T, Francis N, et al
    Biomarker measurement in non-invasively sampled colorectal mucus as a novel approach to colorectal cancer detection: screening and triage implications.
    Br J Cancer. 2020 May 13. pii: 10.1038/s41416-020-0893.
    PubMed     Abstract available


    April 2020
  26. BARISCIANO G, Colangelo T, Rosato V, Muccillo L, et al
    Correction: miR-27a is a master regulator of metabolic reprogramming and chemoresistance in colorectal cancer.
    Br J Cancer. 2020 Apr 17. pii: 10.1038/s41416-020-0855.
    PubMed     Abstract available


    March 2020
  27. MILANO G, Gal J
    Comment on: "Exploring the best treatment options for BRAF-mutant metastatic colon cancer".
    Br J Cancer. 2020 Mar 31. pii: 10.1038/s41416-020-0819.
    PubMed    


  28. AMITAY EL, Carr PR, Jansen L, Roth W, et al
    Smoking, alcohol consumption and colorectal cancer risk by molecular pathological subtypes and pathways.
    Br J Cancer. 2020 Mar 30. pii: 10.1038/s41416-020-0803.
    PubMed     Abstract available


  29. WANG X, Li D, Sun L, Shen G, et al
    Regulation of the small GTPase Ran by miR-802 modulates proliferation and metastasis in colorectal cancer cells.
    Br J Cancer. 2020 Mar 25. pii: 10.1038/s41416-020-0809.
    PubMed     Abstract available


  30. YUAN Z, Liang X, Zhan Y, Wang Z, et al
    Targeting CD133 reverses drug-resistance via the AKT/NF-kappaB/MDR1 pathway in colorectal cancer.
    Br J Cancer. 2020 Mar 16. pii: 10.1038/s41416-020-0783.
    PubMed     Abstract available


  31. USHER-SMITH JA, Harshfield A, Saunders CL, Sharp SJ, et al
    Correction: External validation of risk prediction models for incident colorectal cancer using UK Biobank.
    Br J Cancer. 2020 Mar 12. pii: 10.1038/s41416-020-0767.
    PubMed     Abstract available


  32. HARUKI K, Kosumi K, Li P, Arima K, et al
    An integrated analysis of lymphocytic reaction, tumour molecular characteristics and patient survival in colorectal cancer.
    Br J Cancer. 2020 Mar 11. pii: 10.1038/s41416-020-0780.
    PubMed     Abstract available


  33. BARNES EME, Xu Y, Benito A, Herendi L, et al
    Lactic acidosis induces resistance to the pan-Akt inhibitor uprosertib in colon cancer cells.
    Br J Cancer. 2020 Mar 10. pii: 10.1038/s41416-020-0777.
    PubMed     Abstract available


  34. BARISCIANO G, Colangelo T, Rosato V, Muccillo L, et al
    miR-27a is a master regulator of metabolic reprogramming and chemoresistance in colorectal cancer.
    Br J Cancer. 2020 Mar 5. pii: 10.1038/s41416-020-0773.
    PubMed     Abstract available


  35. OTANDAULT A, Abraham JD, Al Amir Dache Z, Khalyfa A, et al
    Hypoxia differently modulates the release of mitochondrial and nuclear DNA.
    Br J Cancer. 2020;122:715-725.
    PubMed     Abstract available


    February 2020
  36. BANDO H, Kagawa Y, Kato T, Akagi K, et al
    Correction: A multicentre, prospective study of plasma circulating tumour DNA test for detecting RAS mutation in patients with metastatic colorectal cancer.
    Br J Cancer. 2020 Feb 25. pii: 10.1038/s41416-020-0766.
    PubMed     Abstract available


  37. MORIMOTO Y, Mizushima T, Wu X, Okuzaki D, et al
    miR-4711-5p regulates cancer stemness and cell cycle progression via KLF5, MDM2 and TFDP1 in colon cancer cells.
    Br J Cancer. 2020 Feb 18. pii: 10.1038/s41416-020-0758.
    PubMed     Abstract available


  38. GUO F, De Brabander I, Francart J, Candeur M, et al
    Benefits of switching from guaiac-based faecal occult blood to faecal immunochemical testing: experience from the Wallonia-Brussels colorectal cancer screening programme.
    Br J Cancer. 2020 Feb 18. pii: 10.1038/s41416-020-0754.
    PubMed     Abstract available


  39. VAN DE BEEK I, Glykofridis IE, Wolthuis RMF, Gille HJJP, et al
    No evidence for increased prevalence of colorectal carcinoma in 399 Dutch patients with Birt-Hogg-Dube syndrome.
    Br J Cancer. 2020;122:590-594.
    PubMed     Abstract available


    January 2020
  40. ARMSTRONG D, Dregan A, Ashworth M, White P, et al
    The association between colorectal cancer and prior antibiotic prescriptions: case control study.
    Br J Cancer. 2020 Jan 13. pii: 10.1038/s41416-019-0701.
    PubMed     Abstract available


  41. LIANG Y, Zhu D, Hou L, Wang Y, et al
    MiR-107 confers chemoresistance to colorectal cancer by targeting calcium-binding protein 39.
    Br J Cancer. 2020 Jan 10. pii: 10.1038/s41416-019-0703.
    PubMed     Abstract available


    December 2019
  42. HOU P, Shi P, Jiang T, Yin H, et al
    DKC1 enhances angiogenesis by promoting HIF-1alpha transcription and facilitates metastasis in colorectal cancer.
    Br J Cancer. 2019 Dec 20. pii: 10.1038/s41416-019-0695.
    PubMed     Abstract available


  43. WU L, Zhou Z, Han S, Chen J, et al
    PLAGL2 promotes epithelial-mesenchymal transition and mediates colorectal cancer metastasis via beta-catenin-dependent regulation of ZEB1.
    Br J Cancer. 2019 Dec 12. pii: 10.1038/s41416-019-0679.
    PubMed     Abstract available


  44. FU M, Chen D, Luo F, Li M, et al
    Association of the tumour stroma percentage in the preoperative biopsies with lymph node metastasis in colorectal cancer.
    Br J Cancer. 2019 Dec 2. pii: 10.1038/s41416-019-0671.
    PubMed     Abstract available


    October 2019
  45. KUWAHARA T, Hazama S, Suzuki N, Yoshida S, et al
    Correction: Intratumoural-infiltrating CD4 + and FOXP3 + T cells as strong positive predictive markers for the prognosis of resectable colorectal cancer.
    Br J Cancer. 2019 Oct 17. pii: 10.1038/s41416-019-0605.
    PubMed     Abstract available


  46. SAHIN IH, Akce M, Alese O, Shaib W, et al
    Immune checkpoint inhibitors for the treatment of MSI-H/MMR-D colorectal cancer and a perspective on resistance mechanisms.
    Br J Cancer. 2019 Oct 14. pii: 10.1038/s41416-019-0599.
    PubMed     Abstract available


    September 2019
  47. CIRONE M, Lotti LV, Granato M, Renzo LD, et al
    Sourcing the immune system to induce immunogenic cell death in Kras-colorectal cancer cells.
    Br J Cancer. 2019 Sep 27. pii: 10.1038/s41416-019-0561.
    PubMed     Abstract available


  48. DASHTI SG, Li WY, Buchanan DD, Clendenning M, et al
    Type 2 diabetes mellitus, blood cholesterol, triglyceride and colorectal cancer risk in Lynch syndrome.
    Br J Cancer. 2019 Sep 25. pii: 10.1038/s41416-019-0580.
    PubMed     Abstract available


  49. GLAIRE MA, Domingo E, Sveen A, Bruun J, et al
    Correction: Tumour-infiltrating CD8(+) lymphocytes and colorectal cancer recurrence by tumour and nodal stage.
    Br J Cancer. 2019 Sep 23. pii: 10.1038/s41416-019-0590.
    PubMed     Abstract available


  50. ZHAO J, Giri A, Zhu X, Shrubsole MJ, et al
    Calcium: magnesium intake ratio and colorectal carcinogenesis, results from the prostate, lung, colorectal, and ovarian cancer screening trial.
    Br J Cancer. 2019 Sep 23. pii: 10.1038/s41416-019-0579.
    PubMed     Abstract available


  51. KUWAHARA T, Hazama S, Suzuki N, Yoshida S, et al
    Intratumoural-infiltrating CD4 + and FOXP3 + T cells as strong positive predictive markers for the prognosis of resectable colorectal cancer.
    Br J Cancer. 2019 Sep 6. pii: 10.1038/s41416-019-0559.
    PubMed     Abstract available


  52. LOUPAKIS F, Biason P, Prete AA, Cremolini C, et al
    CK7 and consensus molecular subtypes as major prognosticators in (V600E)BRAF mutated metastatic colorectal cancer.
    Br J Cancer. 2019 Sep 2. pii: 10.1038/s41416-019-0560.
    PubMed     Abstract available


    August 2019
  53. KORPHAISARN K, Morris V, Davis JS, Overman MJ, et al
    Signet ring cell colorectal cancer: genomic insights into a rare subpopulation of colorectal adenocarcinoma.
    Br J Cancer. 2019 Aug 13. pii: 10.1038/s41416-019-0548.
    PubMed     Abstract available


  54. GLAIRE MA, Domingo E, Sveen A, Bruun J, et al
    Tumour-infiltrating CD8(+) lymphocytes and colorectal cancer recurrence by tumour and nodal stage.
    Br J Cancer. 2019 Aug 7. pii: 10.1038/s41416-019-0540.
    PubMed     Abstract available


    July 2019
  55. ELEZ E, Pericay C, Valladares-Ayerbes M, Bando I, et al
    A phase 2 study of panitumumab with irinotecan as salvage therapy in chemorefractory KRAS exon 2 wild-type metastatic colorectal cancer patients.
    Br J Cancer. 2019 Jul 31. pii: 10.1038/s41416-019-0537.
    PubMed     Abstract available


  56. PFUDERER PL, Ballhausen A, Seidler F, Stark HJ, et al
    High endothelial venules are associated with microsatellite instability, hereditary background and immune evasion in colorectal cancer.
    Br J Cancer. 2019 Jul 30. pii: 10.1038/s41416-019-0514.
    PubMed     Abstract available


  57. TAIEB J, Lapeyre-Prost A, Laurent Puig P, Zaanan A, et al
    Exploring the best treatment options for BRAF-mutant metastatic colon cancer.
    Br J Cancer. 2019 Jul 29. pii: 10.1038/s41416-019-0526.
    PubMed     Abstract available


  58. GORBUNOVA V, Beck JT, Hofheinz RD, Garcia-Alfonso P, et al
    Correction: A phase 2 randomised study of veliparib plus FOLFIRI+/-bevacizumab versus placebo plus FOLFIRI+/-bevacizumab in metastatic colorectal cancer.
    Br J Cancer. 2019 Jul 26. pii: 10.1038/s41416-019-0528.
    PubMed     Abstract available


  59. KROUPA M, Rachakonda SK, Liska V, Srinivas N, et al
    Relationship of telomere length in colorectal cancer patients with cancer phenotype and patient prognosis.
    Br J Cancer. 2019 Jul 17. pii: 10.1038/s41416-019-0525.
    PubMed     Abstract available


  60. AUCLIN E, Andre T, Taieb J, Banzi M, et al
    Association of post-operative CEA with survival and oxaliplatin benefit in patients with stage II colon cancer: a post hoc analysis of the MOSAIC trial.
    Br J Cancer. 2019 Jul 12. pii: 10.1038/s41416-019-0521.
    PubMed     Abstract available


  61. MEZHEYEUSKI A, Hrynchyk I, Herrera M, Karlberg M, et al
    Stroma-normalised vessel density predicts benefit from adjuvant fluorouracil-based chemotherapy in patients with stage II/III colon cancer.
    Br J Cancer. 2019 Jul 10. pii: 10.1038/s41416-019-0519.
    PubMed     Abstract available


  62. OKI E, Emi Y, Yamanaka T, Uetake H, et al
    Randomised phase II trial of mFOLFOX6 plus bevacizumab versus mFOLFOX6 plus cetuximab as first-line treatment for colorectal liver metastasis (ATOM trial).
    Br J Cancer. 2019;121:222-229.
    PubMed     Abstract available


  63. REZENDE LFM, Lee DH, Keum N, Nimptsch K, et al
    Physical activity during adolescence and risk of colorectal adenoma later in life: results from the Nurses' Health Study II.
    Br J Cancer. 2019;121:86-94.
    PubMed     Abstract available


    May 2019
  64. CHARITOU T, Srihari S, Lynn MA, Jarboui MA, et al
    Transcriptional and metabolic rewiring of colorectal cancer cells expressing the oncogenic KRAS(G13D) mutation.
    Br J Cancer. 2019 May 28. pii: 10.1038/s41416-019-0477.
    PubMed     Abstract available


  65. SYRIOPOULOU E, Morris E, Finan PJ, Lambert PC, et al
    Understanding the impact of socioeconomic differences in colorectal cancer survival: potential gain in life-years.
    Br J Cancer. 2019 May 1. pii: 10.1038/s41416-019-0455.
    PubMed     Abstract available


    April 2019
  66. BANDO H, Kagawa Y, Kato T, Akagi K, et al
    A multicentre, prospective study of plasma circulating tumour DNA test for detecting RAS mutation in patients with metastatic colorectal cancer.
    Br J Cancer. 2019 Apr 24. pii: 10.1038/s41416-019-0457.
    PubMed     Abstract available


  67. NAGATA H, Ishihara S, Abe H, Ushiku T, et al
    LGR5 expression predicts peritoneal recurrence after curative resection of primary colon cancer.
    Br J Cancer. 2019 Apr 19. pii: 10.1038/s41416-019-0442.
    PubMed     Abstract available


  68. XU X, Zhu L, Yang Y, Pan Y, et al
    Low tumour PPM1H indicates poor prognosis in colorectal cancer via activation of cancer-associated fibroblasts.
    Br J Cancer. 2019 Apr 16. pii: 10.1038/s41416-019-0450.
    PubMed     Abstract available


  69. MOON JH, Hong SW, Kim JE, Shin JS, et al
    Targeting beta-catenin overcomes MEK inhibition resistance in colon cancer with KRAS and PIK3CA mutations.
    Br J Cancer. 2019 Apr 4. pii: 10.1038/s41416-019-0434.
    PubMed     Abstract available


  70. KATHER JN, Halama N
    Harnessing the innate immune system and local immunological microenvironment to treat colorectal cancer.
    Br J Cancer. 2019 Apr 2. pii: 10.1038/s41416-019-0441.
    PubMed     Abstract available


  71. STROWITZKI MJ, Radhakrishnan P, Pavicevic S, Scheer J, et al
    High hepatic expression of PDK4 improves survival upon multimodal treatment of colorectal liver metastases.
    Br J Cancer. 2019;120:675-688.
    PubMed     Abstract available


    March 2019
  72. OH HJ, Bae JM, Wen X, Jung S, et al
    p53 expression status is associated with cancer-specific survival in stage III and high-risk stage II colorectal cancer patients treated with oxaliplatin-based adjuvant chemotherapy.
    Br J Cancer. 2019 Mar 21. pii: 10.1038/s41416-019-0429.
    PubMed     Abstract available


  73. IJSSELSTEIJN ME, Petitprez F, Lacroix L, Ruano D, et al
    Revisiting immune escape in colorectal cancer in the era of immunotherapy.
    Br J Cancer. 2019 Mar 13. pii: 10.1038/s41416-019-0421.
    PubMed     Abstract available


  74. TOMITA N, Kunieda K, Maeda A, Hamada C, et al
    Phase III randomised trial comparing 6 vs. 12-month of capecitabine as adjuvant chemotherapy for patients with stage III colon cancer: final results of the JFMC37-0801 study.
    Br J Cancer. 2019 Mar 5. pii: 10.1038/s41416-019-0410.
    PubMed     Abstract available


  75. MARTIN V, Chiriaco C, Modica C, Acquadro A, et al
    Met inhibition revokes IFNgamma-induction of PD-1 ligands in MET-amplified tumours.
    Br J Cancer. 2019;120:527-536.
    PubMed     Abstract available


    February 2019
  76. RASMUSSEN S, Haastrup PF, Balasubramaniam K, Elnegaard S, et al
    Predictive values of colorectal cancer alarm symptoms in the general population: a nationwide cohort study.
    Br J Cancer. 2019 Feb 22. pii: 10.1038/s41416-019-0385.
    PubMed     Abstract available


    January 2019
  77. VARKARIS A, Katsiampoura A, Davis JS, Shah N, et al
    Circulating inflammation signature predicts overall survival and relapse-free survival in metastatic colorectal cancer.
    Br J Cancer. 2019 Jan 14. pii: 10.1038/s41416-018-0360.
    PubMed     Abstract available


  78. GOEPPERT B, Roessler S, Renner M, Singer S, et al
    Mismatch repair deficiency is a rare but putative therapeutically relevant finding in non-liver fluke associated cholangiocarcinoma.
    Br J Cancer. 2019;120:109-114.
    PubMed     Abstract available


    December 2018
  79. PAEZ D, Tobena M, Fernandez-Plana J, Sebio A, et al
    Pharmacogenetic clinical randomised phase II trial to evaluate the efficacy and safety of FOLFIRI with high-dose irinotecan (HD-FOLFIRI) in metastatic colorectal cancer patients according to their UGT1A 1 genotype.
    Br J Cancer. 2018 Dec 26. pii: 10.1038/s41416-018-0348.
    PubMed     Abstract available


  80. CROSS AJ, Wooldrage K, Robbins EC, Pack K, et al
    Whole-colon investigation vs. flexible sigmoidoscopy for suspected colorectal cancer based on presenting symptoms and signs: a multicentre cohort study.
    Br J Cancer. 2018 Dec 19. pii: 10.1038/s41416-018-0335.
    PubMed     Abstract available


  81. SIRNIO P, Vayrynen JP, Klintrup K, Makela J, et al
    Alterations in serum amino-acid profile in the progression of colorectal cancer: associations with systemic inflammation, tumour stage and patient survival.
    Br J Cancer. 2018 Dec 19. pii: 10.1038/s41416-018-0357.
    PubMed     Abstract available


  82. WANG J, Shibayama Y, Zhang A, Ohsaki H, et al
    (Pro)renin receptor promotes colorectal cancer through the Wnt/beta-catenin signalling pathway despite constitutive pathway component mutations.
    Br J Cancer. 2018 Dec 17. pii: 10.1038/s41416-018-0350.
    PubMed     Abstract available


  83. GORBUNOVA V, Beck JT, Hofheinz RD, Garcia-Alfonso P, et al
    A phase 2 randomised study of veliparib plus FOLFIRI+/-bevacizumab versus placebo plus FOLFIRI+/-bevacizumab in metastatic colorectal cancer.
    Br J Cancer. 2018 Dec 11. pii: 10.1038/s41416-018-0343.
    PubMed     Abstract available


    November 2018
  84. LOUPAKIS F, Hurwitz HI, Saltz L, Arnold D, et al
    Impact of primary tumour location on efficacy of bevacizumab plus chemotherapy in metastatic colorectal cancer.
    Br J Cancer. 2018 Nov 29. pii: 10.1038/s41416-018-0304.
    PubMed     Abstract available


  85. GILBERT DC, Wakeham K, Langley RE, Vale CL, et al
    Increased risk of second cancers at sites associated with HPV after a prior HPV-associated malignancy, a systematic review and meta-analysis.
    Br J Cancer. 2018 Nov 28. pii: 10.1038/s41416-018-0273.
    PubMed     Abstract available


  86. GARCIA-FONCILLAS J, Tabernero J, Elez E, Aranda E, et al
    Prospective multicenter real-world RAS mutation comparison between OncoBEAM-based liquid biopsy and tissue analysis in metastatic colorectal cancer.
    Br J Cancer. 2018 Nov 23. pii: 10.1038/s41416-018-0293.
    PubMed     Abstract available


  87. HANSEN TF, Kjaer-Frifeldt S, Eriksen AC, Lindebjerg J, et al
    Prognostic impact of CDX2 in stage II colon cancer: results from two nationwide cohorts.
    Br J Cancer. 2018 Nov 14. pii: 10.1038/s41416-018-0285.
    PubMed     Abstract available


  88. ROBLES-ZURITA J, Boyd KA, Briggs AH, Iveson T, et al
    SCOT: a comparison of cost-effectiveness from a large randomised phase III trial of two durations of adjuvant Oxaliplatin combination chemotherapy for colorectal cancer.
    Br J Cancer. 2018 Nov 13. pii: 10.1038/s41416-018-0319.
    PubMed     Abstract available


  89. KIM BK, Nam SW, Min BS, Ban HS, et al
    Bcl-2-dependent synthetic lethal interaction of the IDF-11774 with the V0 subunit C of vacuolar ATPase (ATP6V0C) in colorectal cancer.
    Br J Cancer. 2018 Nov 13. pii: 10.1038/s41416-018-0289.
    PubMed     Abstract available


  90. MA Y, Yang W, Song M, Smith-Warner SA, et al
    Type 2 diabetes and risk of colorectal cancer in two large U.S. prospective cohorts.
    Br J Cancer. 2018 Nov 7. pii: 10.1038/s41416-018-0314.
    PubMed     Abstract available


  91. TRINH A, Ladrach C, Dawson HE, Ten Hoorn S, et al
    Tumour budding is associated with the mesenchymal colon cancer subtype and RAS/RAF mutations: a study of 1320 colorectal cancers with Consensus Molecular Subgroup (CMS) data.
    Br J Cancer. 2018 Nov 2. pii: 10.1038/s41416-018-0230.
    PubMed     Abstract available


    October 2018
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  95. BARTOLOME RA, Jaen M, Casal JI
    An IL13Ralpha2 peptide exhibits therapeutic activity against metastatic colorectal cancer.
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  96. UZUNPARMAK B, Sahin IH
    Comment on "ERK and p38MAPK combine to improve survival in patients with BRAF mutant colorectal cancer".
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  97. ROSEWEIR AK, McMillan DC, Edwards J
    Reply to comment of "ERK and p38MAPK combine to improve survival in patients with BRAF mutant colorectal cancer".
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  98. HALIM S, Markert EK, Vazquez A
    Analysis of cell proliferation and tissue remodelling uncovers a KLF4 activity score associated with poor prognosis in colorectal cancer.
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  99. BRENNER H, Chen C
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  100. CARVAJAL-CARMONA LG
    Moving the needle on colorectal cancer genetics: it takes more than two to TANGO.
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    The value of using the faecal immunochemical test in general practice on patients presenting with non-alarm symptoms of colorectal cancer.
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    Early metabolic response in sequential FDG-PET/CT under cetuximab is a predictive marker for clinical response in first-line metastatic colorectal cancer patients: results of the phase II REMOTUX trial.
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    September 2017
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    Evidence for genetic association between chromosome 1q loci and predisposition to colorectal neoplasia.
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    August 2017
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    Long-term outcomes of patients with 10 or more colorectal liver metastases.
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