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  Colorectal Neoplasms

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Articles published in Cancer Res

Retrieve available abstracts of 50 articles:
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Single Articles


    December 2025
  1. DALAL PJ, Shah YM
    Gut Check: Lactobacillus johnsonii Harnesses Bile Acids and Reactive Oxygen Species to Suppress High-Fat Diet-Induced Colorectal Cancer.
    Cancer Res. 2025;85:4579-4581.
    PubMed     Abstract available


  2. ARNOUK SM, Kancheva D, Van Damme H, Courtoy GE, et al
    Depleting IL1R2+ Tumor-Infiltrating Regulatory T Cells with an ADCC-Prone Nanobody Construct Boosts the Efficacy of Anti-PD-1 Immunotherapy.
    Cancer Res. 2025;85:4681-4700.
    PubMed     Abstract available


  3. ZHAO J, Chen B, Deng Y, Fan L, et al
    ChREBP-Mediated Choline Deprivation and Chemokine Secretion Shape Tumor-Associated Macrophages to Promote Immune Evasion.
    Cancer Res. 2025;85:4701-4717.
    PubMed     Abstract available


    November 2025
  4. GILLETTE A, Udgata S, Schmitz AE, Stoecker JN, et al
    Wide-Field Optical Redox Imaging with Leading-Edge Detection Enables Assessment of Treatment Response and Heterogeneity in Patient-Derived Cancer Organoids.
    Cancer Res. 2025;85:4329-4340.
    PubMed     Abstract available


  5. MOHAMMAD MIRZAEI N, Hur C, Terry MB, Dalerba P, et al
    Modeling Early-Onset Cancer Kinetics Reveals Changes in Underlying Risk and the Impact of Population Screening.
    Cancer Res. 2025;85:4558-4570.
    PubMed     Abstract available


  6. NATTRESS CB, O'Sullivan R, Fowler D, Hutton C, et al
    Phenoscaping Reveals Multimodal gammadelta T-cell Cytotoxicity as a Strategy to Overcome Cancer Cell-Mediated Immunomodulation.
    Cancer Res. 2025;85:4415-4432.
    PubMed     Abstract available


  7. FUMET JD, Latour C, Nuttin L, Derangere V, et al
    Tumor-Associated Macrophages Produce PGE2 to Promote CD8+ T Cell Exhaustion and Drive Resistance to PD-L1 Blockade in Microsatellite Stable Colorectal Cancer.
    Cancer Res. 2025 Nov 6. doi: 10.1158/0008-5472.CAN-25-0079.
    PubMed     Abstract available


    October 2025
  8. BRUNET GUASCH M, Feeley NA, Soriano I, Thorn S, et al
    Mathematical Modeling Quantifies "Just-Right" APC Inactivation for Colorectal Cancer Initiation.
    Cancer Res. 2025 Oct 15. doi: 10.1158/0008-5472.CAN-25-0445.
    PubMed     Abstract available


  9. LI B, Li H, Li Y, Chen Z, et al
    Genetic Control of tRNA-Derived Fragments Contributes to Cancer Risk.
    Cancer Res. 2025;85:3855-3874.
    PubMed     Abstract available


  10. LIU S, Zhang Z, Wang Z, Liu C, et al
    SPP1 Drives Colorectal Cancer Liver Metastasis and Immunotherapy Resistance by Stimulating CXCL12 Production in Cancer-Associated Fibroblasts.
    Cancer Res. 2025 Oct 6. doi: 10.1158/0008-5472.CAN-24-4916.
    PubMed     Abstract available


  11. SCHATTON D, Frezza C
    Alternatively Spliced Citrate Synthase Supports Colorectal Cancer.
    Cancer Res. 2025 Oct 1:OF1-OF3. doi: 10.1158/0008-5472.CAN-25-3356.
    PubMed     Abstract available


    September 2025
  12. MODL B, Zwolanek D, Schwertner K, Krauss D, et al
    TYK2 Promotes Immunosurveillance of Colorectal Cancer Liver Metastasis.
    Cancer Res. 2025 Sep 24. doi: 10.1158/0008-5472.CAN-24-4224.
    PubMed     Abstract available


  13. ZHOU M, Liu H, Hui J, Chen Q, et al
    Extracellular Vesicle-Packaged miR-99a Reprograms Fibroblasts to Create an Inflammatory Niche that Drives Colorectal Cancer Metastasis.
    Cancer Res. 2025 Sep 24. doi: 10.1158/0008-5472.CAN-25-0663.
    PubMed     Abstract available


  14. SUN F, Wang K, Dong X, Secaira-Morocho H, et al
    The Microbial Bile Acid Metabolite 3-oxo-LCA Inhibits Colorectal Cancer Progression.
    Cancer Res. 2025 Sep 16. doi: 10.1158/0008-5472.CAN-24-3898.
    PubMed     Abstract available


  15. LIU C, Lai P, Hu J, Yin S, et al
    Lactobacillus johnsonii Synthesizes Chenodeoxycholic Acid to Reduce Susceptibility to High-Fat Diet-Induced Colorectal Cancer.
    Cancer Res. 2025 Sep 15. doi: 10.1158/0008-5472.CAN-25-0879.
    PubMed     Abstract available


  16. CHEUNG JCT, Ng LW, Zhu Z, Chen B, et al
    A Citrate Synthase Splice Variant Rewires the TCA Cycle to Promote Colorectal Cancer Progression.
    Cancer Res. 2025 Sep 3. doi: 10.1158/0008-5472.CAN-24-2355.
    PubMed     Abstract available


    August 2025
  17. ZHOU HM, Liu Y, Shi F, Qiu HW, et al
    CLK2 Regulates the KEAP1/NRF2 and p53 Pathways to Suppress Ferroptosis in Colorectal Cancer.
    Cancer Res. 2025 Aug 29. doi: 10.1158/0008-5472.CAN-24-4949.
    PubMed     Abstract available


  18. ZHENG Z, Yuan F, Li J, Zhu X, et al
    Gut Microbiota-Mediated Bile Acid Metabolism Regulates Colorectal Cancer Liver Metastasis by Altering Neutrophil Recruitment.
    Cancer Res. 2025 Aug 27. doi: 10.1158/0008-5472.CAN-24-4425.
    PubMed     Abstract available


  19. SHORT SP
    Ferreting Out Ferroptosis: Extending the Mechanism of Action of RSL3 to the Selenoproteome in Colorectal Cancer.
    Cancer Res. 2025;85:2775-2777.
    PubMed     Abstract available


  20. OLIVEIRA EA, Milite S, Fernandez-Mateos J, Cresswell GD, et al
    Epigenetic Heritability of Cell Plasticity Drives Cancer Drug Resistance through a One-to-Many Genotype-to-Phenotype Paradigm.
    Cancer Res. 2025;85:2921-2938.
    PubMed     Abstract available


    May 2025
  21. DEANGELO SL, Zhao L, Dziechciarz S, Shin M, et al
    Recharacterization of the Tumor Suppressive Mechanism of RSL3 Identifies the Selenoproteome as a Druggable Pathway in Colorectal Cancer.
    Cancer Res. 2025 May 20. doi: 10.1158/0008-5472.CAN-24-3478.
    PubMed     Abstract available


  22. MATEJCIC M, Teer JK, Hoehn HJ, Diaz DB, et al
    Colorectal Tumors in Diverse Patient Populations Feature a Spectrum of Somatic Mutational Profiles.
    Cancer Res. 2025;85:1928-1944.
    PubMed     Abstract available


  23. BUCKENMEYER MJ, Brooks EA, Taylor MS, Orenuga IK, et al
    A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates In Vivo Tumor Phenotypes and Heterogeneity.
    Cancer Res. 2025;85:1577-1595.
    PubMed     Abstract available


    March 2025
  24. TIKUM AF, Henning NW, Pougoue Ketchemen J, Doroudi A, et al
    An Anti-EGFR Antibody-Drug Radioconjugate Labeled with Actinium-225 Elicits Durable Anti-Tumor Responses in KRAS and BRAF Mutant Colorectal Cancer.
    Cancer Res. 2025 Mar 24. doi: 10.1158/0008-5472.CAN-24-2266.
    PubMed     Abstract available


    February 2025
  25. LIN Y, Zhang Y, Huang T, Chen J, et al
    Arginine Deprivation Induces Quiescence and Confers Vulnerability to Ferroptosis in Colorectal Cancer.
    Cancer Res. 2025 Feb 24. doi: 10.1158/0008-5472.CAN-24-1940.
    PubMed     Abstract available


  26. DENG S, Wang J, Zou F, Cheng D, et al
    Palmitic Acid Accumulation Activates Fibroblasts and Promotes Matrix Stiffness in Colorectal Cancer.
    Cancer Res. 2025 Feb 24. doi: 10.1158/0008-5472.CAN-24-2892.
    PubMed     Abstract available


  27. XU J, Meng Q, Li X, Yang H, et al
    Correction: Long Noncoding RNA MIR17HG Promotes Colorectal Cancer Progression via miR-17-5p.
    Cancer Res. 2025;85:826.
    PubMed    


  28. CASTRO J, Daniels MH, Brennan D, Johnston B, et al
    A Potent, Selective, Small-Molecule Inhibitor of DHX9 Abrogates Proliferation of Microsatellite Instable Cancers with Deficient Mismatch Repair.
    Cancer Res. 2025;85:758-776.
    PubMed     Abstract available


    January 2025
  29. LI D, Liu X, Gao W, Zhao W, et al
    An Immune Subtype Classification System Enables the Development of Strategies to Predict and Enhance Immunotherapy Responses in Colorectal Cancer.
    Cancer Res. 2025 Jan 29. doi: 10.1158/0008-5472.CAN-24-2464.
    PubMed     Abstract available


  30. KALLIO P, Bessone C, Seyednasrollah F, Brodkin J, et al
    A Multipotent PROX1+ Tumor Stem/Progenitor Cell Population Emerges During Intestinal Tumorigenesis and Mediates Radioresistance in Colorectal Cancer.
    Cancer Res. 2025 Jan 22. doi: 10.1158/0008-5472.CAN-23-1851.
    PubMed     Abstract available


    December 2024
  31. JACOB J, Anami Y, High PC, Liang Z, et al
    Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer.
    Cancer Res. 2024 Dec 18. doi: 10.1158/0008-5472.CAN-24-0798.
    PubMed     Abstract available


  32. CUI L, Liu R, Han S, Zhang C, et al
    Targeting Arachidonic Acid Metabolism Enhances Immunotherapy Efficacy in ARID1A-Deficient Colorectal Cancer.
    Cancer Res. 2024 Dec 9. doi: 10.1158/0008-5472.CAN-24-1611.
    PubMed     Abstract available


  33. GUO X, Luo S, Wang X, Cui Y, et al
    CD24-Targeted NIR-II Fluorescence Imaging Enables Early Detection of Colorectal Neoplasia.
    Cancer Res. 2024;84:4099-4113.
    PubMed     Abstract available


    October 2024
  34. CHUA J, Gregorieff A, Ayyaz A
    Bottom-up or Top-down: Inflammation Reprograms Paneth Cells to Develop Bowel Cancers.
    Cancer Res. 2024;84:3324-3326.
    PubMed     Abstract available


  35. LADAIKA CA, Ghobashi AH, Boulton WC, Miller SA, et al
    LSD1 and CoREST2 Potentiate STAT3 Activity to Promote Enteroendocrine Cell Differentiation in Mucinous Colorectal Cancer.
    Cancer Res. 2024 Oct 4. doi: 10.1158/0008-5472.CAN-24-0788.
    PubMed     Abstract available


  36. ROLFO C, Russo A
    The Next Frontier for Colorectal Cancer Screening: Blood-Based Tests.
    Cancer Res. 2024;84:3128-3129.
    PubMed     Abstract available


    September 2024
  37. WANG H, Chen J, Chen X, Liu Y, et al
    Cancer-Associated Fibroblasts Expressing Sulfatase 1 Facilitate VEGFA-Dependent Microenvironmental Remodeling to Support Colorectal Cancer.
    Cancer Res. 2024 Sep 9. doi: 10.1158/0008-5472.CAN-23-3987.
    PubMed     Abstract available


  38. CHEN D, Ji F, Zhou Q, Cheung H, et al
    RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m6A-Dependent Oncogenic Translation and Colorectal Tumorigenesis.
    Cancer Res. 2024;84:2856-2872.
    PubMed     Abstract available


  39. SHU Y, Jin X, Ji M, Zhang Z, et al
    Ku70 Binding to YAP Alters PARP1 Ubiquitination to Regulate Genome Stability and Tumorigenesis.
    Cancer Res. 2024;84:2836-2855.
    PubMed     Abstract available


    August 2024
  40. SAHA S, Ghosh M, Li J, Wen A, et al
    Serine Depletion Promotes Antitumor Immunity by Activating Mitochondrial DNA-Mediated cGAS-STING Signaling.
    Cancer Res. 2024;84:2645-2659.
    PubMed     Abstract available


    July 2024
  41. CAO Y, Wang N, Wu X, Tang W, et al
    Multi-Dimensional Fragmentomics Enables Early and Accurate Detection of Colorectal Cancer.
    Cancer Res. 2024 Jul 29. doi: 10.1158/0008-5472.CAN-23-3486.
    PubMed     Abstract available


  42. LIAO S, Deng J, Deng M, Chen C, et al
    AFDN deficiency promotes liver tropism of metastatic colorectal cancer.
    Cancer Res. 2024 Jul 24. doi: 10.1158/0008-5472.CAN-23-3140.
    PubMed     Abstract available


    June 2024
  43. LI L, Jiang D, Liu H, Guo C, et al
    Comprehensive Proteogenomic Profiling Reveals the Molecular Characteristics of Colorectal Cancer at Distinct Stages of Progression.
    Cancer Res. 2024 Jun 11. doi: 10.1158/0008-5472.CAN-23-1878.
    PubMed     Abstract available


    May 2024
  44. BAKER AM, Nageswaran G, Nenclares P, Ronel T, et al
    FUME-TCRseq Enables Sensitive and Accurate Sequencing of the T-cell Receptor from Limited Input of Degraded RNA.
    Cancer Res. 2024;84:1560-1569.
    PubMed     Abstract available


  45. BAHRAMBEIGI V, Lee JJ, Branchi V, Rajapakshe KI, et al
    Transcriptomic Profiling of Plasma Extracellular Vesicles Enables Reliable Annotation of the Cancer-Specific Transcriptome and Molecular Subtype.
    Cancer Res. 2024;84:1719-1732.
    PubMed     Abstract available


    April 2024
  46. YANG S, Zhang D, Sun Q, Nie H, et al
    Single-Cell and Spatial Transcriptome Profiling Identifies the Transcription Factor BHLHE40 as a Driver of EMT in Metastatic Colorectal Cancer.
    Cancer Res. 2024 Apr 24. doi: 10.1158/0008-5472.CAN-23-3264.
    PubMed     Abstract available


  47. ZHAO N, Cao Y, Tao R, Zhu X, et al
    The circMYBL2-encoded p185 protein suppresses colorectal cancer progression by inhibiting serine biosynthesis.
    Cancer Res. 2024 Apr 18. doi: 10.1158/0008-5472.CAN-23-2940.
    PubMed     Abstract available


  48. CHEN Y, Ying Y, Ma W, Ma H, et al
    Targeting the Epigenetic Reader ENL Inhibits Super-Enhancer-Driven Oncogenic Transcription and Synergizes with BET Inhibition to Suppress Tumor Progression.
    Cancer Res. 2024;84:1237-1251.
    PubMed     Abstract available


    March 2024
  49. MCCOLLUM SE, Shah YM
    Stressing Out Cancer: Chronic Stress Induces Dysbiosis and Enhances Colon Cancer Growth.
    Cancer Res. 2024;84:645-647.
    PubMed     Abstract available


  50. FANG L, Zhang L, Wang M, He Y, et al
    Pooled CRISPR Screening Identifies P-Bodies as Repressors of Cancer Epithelial-Mesenchymal Transition.
    Cancer Res. 2024;84:659-674.
    PubMed     Abstract available


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