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COVID-19: Daily Top 10 Papers


  Colorectal Neoplasms

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Articles published in Cancer Res

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    April 2021
  1. WEI B, Xu L, Guo W, Wang Y, et al
    SHP2-mediated inhibition of DNA repair contributes to cGAS-STING activation and chemotherapeutic sensitivity in colon cancer.
    Cancer Res. 2021 Apr 5. pii: 0008-5472.CAN-20-3738.
    PubMed     Abstract available


    March 2021
  2. WU QN, Luo XJ, Liu J, Lu YX, et al
    MYC-activated lncRNA MNX1-AS1 promotes the progression of colorectal cancer by stabilizing YB1.
    Cancer Res. 2021 Mar 29. pii: 0008-5472.CAN-20-3747.
    PubMed     Abstract available


  3. ADAMCZYK A, Pastille E, Kehrmann J, Vu VP, et al
    GPR15 facilitates recruitment of regulatory T cells to promote colorectal cancer.
    Cancer Res. 2021 Mar 16. pii: 0008-5472.CAN-20-2133.
    PubMed     Abstract available


    February 2021
  4. ZHANG B, Yao K, Zhou E, Zhang L, et al
    Chr20q amplification defines a distinct molecular subtype of microsatellite stable colorectal cancer.
    Cancer Res. 2021 Feb 22. pii: 0008-5472.CAN-20-4009.
    PubMed     Abstract available


  5. ZHOU J, Li Q, Cao Y
    Spatiotemporal Heterogeneity Across Metastases and Organ-Specific Response Informs Drug Efficacy and Patient Survival in Colorectal Cancer.
    Cancer Res. 2021 Feb 15. pii: 0008-5472.CAN-20-3665.
    PubMed     Abstract available


  6. MONTROSE DC, Saha S, Foronda M, McNally EM, et al
    Exogenous and endogenous sources of serine contribute to colon cancer metabolism, growth, and resistance to 5-fluorouracil.
    Cancer Res. 2021 Feb 1. pii: 0008-5472.CAN-20-1541.
    PubMed     Abstract available


    December 2020
  7. BARNOUD T, Leung JC, Leu JI, Basu S, et al
    A Novel Inhibitor of HSP70 Induces Mitochondrial Toxicity and Immune Cell Recruitment in Tumors.
    Cancer Res. 2020;80:5270-5281.
    PubMed     Abstract available


    November 2020
  8. CHEN HN, Liang KH, Lai JK, Lan CH, et al
    EpCAM Signaling Promotes Tumor Progression and Protein Stability of PD-L1 through the EGFR Pathway.
    Cancer Res. 2020;80:5035-5050.
    PubMed     Abstract available


  9. KWOK ZH, Zhang B, Chew XH, Chan JJ, et al
    Systematic analysis of intronic microRNAs reveals cooperativity within the multi-component FTX locus to promote colon cancer development.
    Cancer Res. 2020 Nov 10. pii: 0008-5472.CAN-20-1406.
    PubMed     Abstract available


  10. ZHAO Y, Feng X, Chen Y, Selfridge JE, et al
    5-Fluorouracil Enhances the Antitumor Activity of the Glutaminase Inhibitor CB-839 against PIK3CA-Mutant Colorectal Cancers.
    Cancer Res. 2020;80:4815-4827.
    PubMed     Abstract available


    October 2020
  11. MOSA MH, Michels BE, Menche C, Nicolas AM, et al
    A Wnt-induced phenotypic switch in cancer-associated fibroblasts inhibits EMT in colorectal cancer.
    Cancer Res. 2020 Oct 14. pii: 0008-5472.CAN-20-0263.
    PubMed     Abstract available


  12. LI Y, Bai L, Yu H, Cai D, et al
    Epigenetic inactivation of alpha-internexin accelerates microtubule polymerization in colorectal cancer.
    Cancer Res. 2020 Oct 13. pii: 0008-5472.CAN-20-1590.
    PubMed     Abstract available


  13. WANG TW, Chern E, Hsu CW, Tseng KC, et al
    SIRT1-mediated expression of CD24 and epigenetic suppression of novel tumor suppressor miR-1185-1 increases colorectal cancer stemness.
    Cancer Res. 2020 Oct 12. pii: 0008-5472.CAN-19-3188.
    PubMed     Abstract available


  14. WANG Q, Zhang T, Chang X, Lim DY, et al
    ARC Is a Critical Protector against Inflammatory Bowel Disease (IBD) and IBD-Associated Colorectal Tumorigenesis.
    Cancer Res. 2020;80:4158-4171.
    PubMed     Abstract available


  15. DU L, Fakih MG, Rosen ST, Chen Y, et al
    SUMOylation of E2F1 Regulates Expression of EZH2.
    Cancer Res. 2020;80:4212-4223.
    PubMed     Abstract available


    September 2020
  16. LEONI G, D'Alise AM, Cotugno G, Langone F, et al
    A Genetic Vaccine Encoding Shared Cancer Neoantigens to Treat Tumors with Microsatellite Instability.
    Cancer Res. 2020;80:3972-3982.
    PubMed     Abstract available


  17. GHERGUROVICH JM, Esposito M, Chen Z, Wang JZ, et al
    Glucose-6-Phosphate Dehydrogenase Is Not Essential for K-Ras-Driven Tumor Growth or Metastasis.
    Cancer Res. 2020;80:3820-3829.
    PubMed     Abstract available


  18. JACKSON DN, Alula KM, Delgado-Deida Y, Tabti R, et al
    The Synthetic Small Molecule FL3 Combats Intestinal Tumorigenesis via Axin1-Mediated Inhibition of Wnt/beta-Catenin Signaling.
    Cancer Res. 2020;80:3519-3529.
    PubMed     Abstract available


    August 2020
  19. SHIOKAWA D, Sakai H, Ohata H, Miyazaki T, et al
    Slow-cycling cancer stem cells regulate progression and chemoresistance in colon cancer.
    Cancer Res. 2020 Aug 19. pii: 0008-5472.CAN-20-0378.
    PubMed     Abstract available


  20. UROSEVIC J, Blasco MT, Llorente A, Bellmunt A, et al
    ERK1/2 signaling induces upregulation of ANGPT2 and CXCR4 to mediate liver metastasis in colon cancer.
    Cancer Res. 2020 Aug 19. pii: 0008-5472.CAN-19-4028.
    PubMed     Abstract available


  21. SHOLL LM, Oxnard GR, Paweletz CP
    Traditional Diagnostics versus Disruptive Technology: The Role of the Pathologist in the Era of Liquid Biopsy.
    Cancer Res. 2020;80:3197-3199.
    PubMed     Abstract available


  22. ZHANG Y, Cedervall J, Hamidi A, Herre M, et al
    Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis.
    Cancer Res. 2020;80:3345-3358.
    PubMed     Abstract available


  23. VANKEMMELBEKE M, McIntosh RS, Chua JX, Kirk T, et al
    Engineering the Human Fc Region Enables Direct Cell Killing by Cancer Glycan-Targeting Antibodies without the Need for Immune Effector Cells or Complement.
    Cancer Res. 2020;80:3399-3412.
    PubMed     Abstract available


  24. HIDAKA A, Harrison TA, Cao Y, Sakoda LC, et al
    Intake of dietary fruit, vegetables, and fiber and risk of colorectal cancer according to molecular subtypes: A pooled analysis of 9 studies.
    Cancer Res. 2020 Aug 14. pii: 0008-5472.CAN-20-0168.
    PubMed     Abstract available


    July 2020
  25. HOUSLEY SN, Nardelli P, Carrasco DI, Rotterman TM, et al
    Cancer Exacerbates Chemotherapy-Induced Sensory Neuropathy.
    Cancer Res. 2020;80:2940-2955.
    PubMed     Abstract available


  26. PORTA C, Consonni FM, Morlacchi S, Sangaletti S, et al
    Tumor-Derived Prostaglandin E2 Promotes p50 NF-kappaB-Dependent Differentiation of Monocytic MDSCs.
    Cancer Res. 2020;80:2874-2888.
    PubMed     Abstract available


    June 2020
  27. KALLIO P, Jokinen E, Hogstrom J, Das S, et al
    Blocking Angiopoietin-2 Promotes Vascular Damage and Growth Inhibition in Mouse Tumors Treated with Small Doses of Radiation.
    Cancer Res. 2020;80:2639-2650.
    PubMed     Abstract available


    March 2020
  28. BRUSCHI M, Garnier L, Cleroux E, Giordano A, et al
    Loss of APC Rapidly Impairs DNA Methylation Programs and Cell Fate Decisions in LGR5+ Intestinal Stem Cells.
    Cancer Res. 2020 Mar 25. pii: 0008-5472.CAN-19-2104.
    PubMed     Abstract available


  29. ROGERS RF, Walton MI, Cherry DL, Collins I, et al
    CHK1 inhibition is synthetically lethal with loss of B-family DNA polymerase function in human lung and colorectal cancer cells.
    Cancer Res. 2020 Mar 11. pii: 0008-5472.CAN-19-1372.
    PubMed     Abstract available


  30. TIAN J, Lou J, Cai Y, Rao M, et al
    Risk SNP-mediated enhancer-promoter interaction drives colorectal cancer through both FADS2 and AP002754.2.
    Cancer Res. 2020 Mar 3. pii: 0008-5472.CAN-19-2389.
    PubMed     Abstract available


    January 2020
  31. FERRANDON S, DeVecchio J, Duraes L, Chouhan H, et al
    CoA Synthase (COASY) Mediates Radiation Resistance via PI3K Signaling in Rectal Cancer.
    Cancer Res. 2020;80:334-346.
    PubMed     Abstract available


    November 2019
  32. PLANTUREUX L, Mege D, Crescence L, Carminita E, et al
    The interaction of platelets with colorectal cancer cells inhibits tumor growth but promotes metastasis.
    Cancer Res. 2019 Nov 14. pii: 0008-5472.CAN-19-1181.
    PubMed     Abstract available


  33. ZHOU J, Liu Y, Zhang Y, Li Q, et al
    Modeling tumor evolutionary dynamics to predict clinical outcomes for patients with metastatic colorectal cancer: a retrospective analysis.
    Cancer Res. 2019 Nov 1. pii: 0008-5472.CAN-19-1940.
    PubMed     Abstract available


    October 2019
  34. GRIGORYAN H, Schiffman C, Gunter MJ, Naccarati A, et al
    Cys34 Adductomics Links Colorectal Cancer with the Gut Microbiota and Redox Biology.
    Cancer Res. 2019 Oct 22. pii: 0008-5472.CAN-19-1529.
    PubMed     Abstract available


    September 2019
  35. PELULLO M, Nardozza F, Zema S, Quaranta R, et al
    Kras/ADAM17-dependent Jag1-ICD reverse signalling sustains colorectal cancer progression and chemoresistance.
    Cancer Res. 2019 Sep 10. pii: 0008-5472.CAN-19-0145.
    PubMed     Abstract available


    August 2019
  36. MUKOHYAMA J, Isobe T, Hu Q, Hayashi T, et al
    miR-221 targets QKI to enhance the tumorigenic capacity of human colorectal cancer stem cells.
    Cancer Res. 2019 Aug 15. pii: 0008-5472.CAN-18-3544.
    PubMed     Abstract available


  37. XU J, Meng Q, Li X, Yang H, et al
    Long non-coding RNA MIR17HG promotes colorectal cancer progression via miR-17-5p.
    Cancer Res. 2019 Aug 13. pii: 0008-5472.CAN-18-3880.
    PubMed     Abstract available


    July 2019
  38. TOME M, Pappalardo A, Soulet F, Lopez JJ, et al
    Inactivation of proprotein convertases in T cells inhibits PD-1 expression and creates a favorable immune microenvironment in colorectal cancer.
    Cancer Res. 2019 Jul 29. pii: 0008-5472.CAN-19-0086.
    PubMed     Abstract available


  39. WU S, Sun H, Wang Y, Yang X, et al
    MALAT1 rs664589 polymorphism inhibits binding to miR-194-5p contributing to colorectal cancer risk, growth and metastasis.
    Cancer Res. 2019 Jul 16. pii: 0008-5472.CAN-19-0773.
    PubMed     Abstract available


  40. WANG YQ, Jiang DM, Hu SS, Zhao L, et al
    SATB2-AS1 Suppresses Colorectal Carcinoma Aggressiveness by Inhibiting SATB2-Dependent Snail Transcription and Epithelial-Mesenchymal Transition.
    Cancer Res. 2019;79:3542-3556.
    PubMed     Abstract available


  41. YE YC, Zhao JL, Lu YT, Gao CC, et al
    Notch signaling via Wnt regulates the proliferation of alternative, CCR2-independent tumor-associated macrophages in hepatocellular carcinoma.
    Cancer Res. 2019 Jul 2. pii: 0008-5472.CAN-18-1691.
    PubMed     Abstract available


    June 2019
  42. KAMAL Y, Schmit SL, Hoehn HJ, Amos CI, et al
    Transcriptomic differences between primary colorectal adenocarcinomas and distant metastases reveal metastatic colorectal cancer subtypes.
    Cancer Res. 2019 Jun 25. pii: 0008-5472.CAN-18-3945.
    PubMed     Abstract available


  43. WANG D, Fu L, Wei J, Xiong Y, et al
    PPARdelta mediates the effect of dietary fat in promoting colorectal cancer metastasis.
    Cancer Res. 2019 Jun 25. pii: 0008-5472.CAN-19-0384.
    PubMed     Abstract available


  44. YU J, Wang S, Zhang Y, Huang J, et al
    TRIM67 activates p53 to suppress colorectal cancer initiation and progression.
    Cancer Res. 2019 Jun 25. pii: 0008-5472.CAN-18-3614.
    PubMed     Abstract available


  45. TACCONI C, Ungaro F, Correale C, Arena V, et al
    Activation of the VEGFC/VEGFR3 pathway induces tumor immune escape in colorectal cancer.
    Cancer Res. 2019 Jun 25. pii: 0008-5472.CAN-18-3657.
    PubMed     Abstract available


  46. INDARTE M, Puentes R, Maruggi M, Ihle NT, et al
    An Inhibitor of the Pleckstrin Homology Domain of CNK1 Selectively Blocks the Growth of Mutant KRAS Cells and Tumors.
    Cancer Res. 2019;79:3100-3111.
    PubMed     Abstract available


    May 2019
  47. SANTIAGO I, Santinha J, Ianus A, Galzerano A, et al
    Susceptibility Perturbation MRI Maps Tumor Infiltration into Mesorectal Lymph Nodes.
    Cancer Res. 2019;79:2435-2444.
    PubMed     Abstract available


  48. SHEN A, Chen Y, Liu L, Huang Y, et al
    EBF1-Mediated Upregulation of Ribosome Assembly Factor PNO1 Contributes to Cancer Progression by Negatively Regulating the p53 Signaling Pathway.
    Cancer Res. 2019;79:2257-2270.
    PubMed     Abstract available


    April 2019
  49. COMBES E, Andrade AF, Tosi D, Michaud HA, et al
    Inhibition of Ataxia-Telangiectasia Mutated and RAD3-related (ATR) overcomes oxaliplatin resistance and promotes anti-tumor immunity in colorectal cancer.
    Cancer Res. 2019 Apr 15. pii: 0008-5472.CAN-18-2807.
    PubMed     Abstract available


  50. LOPES-RAMOS CM, Kuijjer ML, Ogino S, Fuchs CS, et al
    Correction: Gene Regulatory Network Analysis Identifies Sex-Linked Differences in Colon Cancer Drug Metabolism.
    Cancer Res. 2019;79:2084.
    PubMed    


  51. WANG W, Yang J, Edin ML, Wang Y, et al
    Targeted Metabolomics Identifies the Cytochrome P450 Monooxygenase Eicosanoid Pathway as a Novel Therapeutic Target of Colon Tumorigenesis.
    Cancer Res. 2019;79:1822-1830.
    PubMed     Abstract available


  52. TRAVELLI C, Consonni FM, Sangaletti S, Storto M, et al
    Nicotinamide Phosphoribosyltransferase Acts as a Metabolic Gate for Mobilization of Myeloid-Derived Suppressor Cells.
    Cancer Res. 2019;79:1938-1951.
    PubMed     Abstract available


  53. HUANG S, Wang Z, Zhou J, Huang J, et al
    EZH2 Inhibitor GSK126 Suppresses Antitumor Immunity by Driving Production of Myeloid-Derived Suppressor Cells.
    Cancer Res. 2019;79:2009-2020.
    PubMed     Abstract available


  54. YOKOYAMA Y, Lew ED, Seelige R, Tindall EA, et al
    Immuno-oncological Efficacy of RXDX-106, a Novel TAM (TYRO3, AXL, MER) Family Small-Molecule Kinase Inhibitor.
    Cancer Res. 2019;79:1996-2008.
    PubMed     Abstract available


  55. JAYAKUMAR A, Bothwell ALM
    RIPK3-Induced Inflammation by I-MDSCs Promotes Intestinal Tumors.
    Cancer Res. 2019;79:1587-1599.
    PubMed     Abstract available


    March 2019
  56. KATONA BW, Glynn RA, Paulosky KE, Feng Z, et al
    Combined menin and EGFR inhibitors synergize to suppress colorectal cancer via EGFR-independent and calcium-mediated repression of SKP2 transcription.
    Cancer Res. 2019 Mar 15. pii: 0008-5472.CAN-18-2133.
    PubMed     Abstract available


  57. VALERI N
    Streamlining Detection of Fusion Genes in Colorectal Cancer: Having "Faith" in Precision Oncology in the (Tissue) "Agnostic" Era.
    Cancer Res. 2019;79:1041-1043.
    PubMed     Abstract available


  58. BISHNUPURI KS, Alvarado DM, Khouri AN, Shabsovich M, et al
    IDO1 and Kynurenine Pathway Metabolites Activate PI3K-Akt Signaling in the Neoplastic Colon Epithelium to Promote Cancer Cell Proliferation and Inhibit Apoptosis.
    Cancer Res. 2019;79:1138-1150.
    PubMed     Abstract available


  59. SALEM M, Wallace C, Velegraki M, Li A, et al
    GARP Dampens Cancer Immunity by Sustaining Function and Accumulation of Regulatory T Cells in the Colon.
    Cancer Res. 2019;79:1178-1190.
    PubMed     Abstract available


  60. COCCO E, Benhamida J, Middha S, Zehir A, et al
    Colorectal Carcinomas Containing Hypermethylated MLH1 Promoter and Wild-Type BRAF/KRAS Are Enriched for Targetable Kinase Fusions.
    Cancer Res. 2019;79:1047-1053.
    PubMed     Abstract available


  61. LIU C, Banister CE, Buckhaults PJ
    Spindle assembly checkpoint inhibition can resensitize p53-null stem cells to cancer chemotherapy.
    Cancer Res. 2019 Mar 12. pii: 0008-5472.CAN-18-3024.
    PubMed     Abstract available


  62. WEISNER J, Landel I, Reintjes C, Uhlenbrock N, et al
    Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib in KRAS-mutant Pancreatic and Colorectal Cancer.
    Cancer Res. 2019 Mar 11. pii: 0008-5472.CAN-18-2861.
    PubMed     Abstract available


  63. LIU Y, Deguchi Y, Tian R, Wei D, et al
    Pleiotropic Effects of PPARD Accelerate Colorectal Tumorigenesis, Progression, and Invasion.
    Cancer Res. 2019;79:954-969.
    PubMed     Abstract available


  64. RAJENDRAN P, Johnson G, Li L, Chen YS, et al
    Acetylation of CCAR2 Establishes a BET/BRD9 Acetyl Switch in Response to Combined Deacetylase and Bromodomain Inhibition.
    Cancer Res. 2019;79:918-927.
    PubMed     Abstract available


    February 2019
  65. TAKEDA M, Koseki J, Takahashi H, Miyoshi N, et al
    Disruption of endolysosomal RAB5/7 efficiently eliminates colorectal cancer stem cells.
    Cancer Res. 2019 Feb 14. pii: 0008-5472.CAN-18-2192.
    PubMed     Abstract available


  66. SAPIENZA C
    Epigenetic Drift in Colorectal Cancer-It's Probably Later Than You Think.
    Cancer Res. 2019;79:437-438.
    PubMed     Abstract available


  67. OSHIMA G, Poli EC, Bolt MJ, Chlenski A, et al
    DNA Methylation Controls Metastasis-Suppressive 14q32-Encoded miRNAs.
    Cancer Res. 2019;79:650-662.
    PubMed     Abstract available


  68. LUEBECK GE, Hazelton WD, Curtius K, Maden SK, et al
    Implications of Epigenetic Drift in Colorectal Neoplasia.
    Cancer Res. 2019;79:495-504.
    PubMed     Abstract available


    January 2019
  69. SCHIAPPACASSE COCIO GV, Schiappacasse ED
    Is Adjuvant Chemotherapy Efficient in Colon Cancer with High Microsatellite Instability? A Look Towards the Future.
    Cancer Res. 2019 Jan 24. pii: 0008-5472.CAN-18-2991.
    PubMed     Abstract available


  70. TAN X, Tong J, Wang YJ, Fletcher R, et al
    BET inhibitors potentiate chemotherapy and killing of SPOP-mutant colon cancer cells via induction of DR5.
    Cancer Res. 2019 Jan 23. pii: 0008-5472.CAN-18-3223.
    PubMed     Abstract available


  71. SHEN J, Zhao W, Ju Z, Wang L, et al
    PARPi Triggers the STING-Dependent Immune Response and Enhances the Therapeutic Efficacy of Immune Checkpoint Blockade Independent of BRCAness.
    Cancer Res. 2019;79:311-319.
    PubMed     Abstract available


    November 2018
  72. ZHANG C, Qu L, Lian S, Meng L, et al
    PRL-3 promotes ubiquitination and degradation of AURKA and colorectal cancer progression via dephosphorylation of FZR1.
    Cancer Res. 2018 Nov 29. pii: 0008-5472.CAN-18-0520.
    PubMed     Abstract available


  73. LAN J, Sun L, Xu F, Liu L, et al
    M2 macrophage-derived exosomes promote cell migration and invasion in colon cancer.
    Cancer Res. 2018 Nov 6. pii: 0008-5472.CAN-18-0014.
    PubMed     Abstract available


    October 2018
  74. LOPES-RAMOS CM, Kuijjer ML, Ogino S, Fuchs CS, et al
    Gene Regulatory Network Analysis Identifies Sex-Linked Differences in Colon Cancer Drug Metabolism.
    Cancer Res. 2018;78:5538-5547.
    PubMed     Abstract available


    September 2018
  75. LIANG J, Chen M, Hughes D, Chumanevich AA, et al
    CDK8 selectively promotes the growth of colon cancer metastases in the liver by regulating gene expression of TIMP3 and matrix metalloproteinases.
    Cancer Res. 2018 Sep 5. pii: 0008-5472.CAN-18-1583.
    PubMed     Abstract available



  76. Editor's Note: Zerumbone Enhances TRAIL-Induced Apoptosis through the Induction of Death Receptors in Human Colon Cancer Cells: Evidence for an Essential Role of Reactive Oxygen Species.
    Cancer Res. 2018;78:5183.
    PubMed    


    August 2018
  77. HOGSTROM J, Heino S, Kallio P, Lahde M, et al
    Transcription factor PROX1 suppresses Notch pathway activation via the nucleosome remodeling and deacetylase complex in colorectal cancer stem-like cells.
    Cancer Res. 2018 Aug 28. pii: 0008-5472.CAN-18-0451.
    PubMed     Abstract available


    July 2018
  78. KRISHNAMURTHY A, Dasari A, Noonan AM, Mehnert JM, et al
    Phase Ib Results of the Rational Combination of Selumetinib and Cyclosporin A in Advanced Solid Tumors with an Expansion Cohort in Metastatic Colorectal Cancer.
    Cancer Res. 2018 Jul 24. pii: 0008-5472.CAN-18-0316.
    PubMed     Abstract available


  79. CHENG J, Dwyer M, Okolotowicz KJ, Mercola M, et al
    A novel inhibitor targets both Wnt signaling and ATM/p53 in colorectal cancer.
    Cancer Res. 2018 Jul 21. pii: 0008-5472.CAN-17-2642.
    PubMed     Abstract available


  80. CHANG J, Tian J, Yang Y, Zhong R, et al
    A rare missense variant in TCF7L2 associates with colorectal cancer risk by interacting with a GWAS-identified regulatory variant in the MYC enhancer.
    Cancer Res. 2018 Jul 19. pii: 0008-5472.CAN-18-0910.
    PubMed     Abstract available


  81. VILLARREAL DO, L'Huillier A, Armington S, Mottershead C, et al
    Targeting CCR8 induces protective antitumor immunity and enhances vaccine-induced responses in colon cancer.
    Cancer Res. 2018 Jul 19. pii: 0008-5472.CAN-18-1119.
    PubMed     Abstract available


  82. STEVENS PD, Wen YA, Xiong X, Zaytseva YY, et al
    Erbin suppresses KSR1-mediated RAS/RAF signaling and tumorigenesis in colorectal cancer.
    Cancer Res. 2018 Jul 6. pii: 0008-5472.CAN-17-3629.
    PubMed     Abstract available


  83. KATHER JN, Charoentong P, Suarez-Carmona M, Herpel E, et al
    High-throughput screening of combinatorial immunotherapies with patient-specific in silico models of metastatic colorectal cancer.
    Cancer Res. 2018 Jul 2. pii: 0008-5472.CAN-18-1126.
    PubMed     Abstract available



  84. Correction: Heterochromatin Protein HP1gamma Promotes Colorectal Cancer Progression and Is Regulated by miR-30a.
    Cancer Res. 2018;78:3741.
    PubMed    


    June 2018
  85. WANG X, Chan AT, Slattery ML, Chang-Claude J, et al
    Influence of smoking, body mass index and other factors on the preventive effect of nonsteroidal anti-inflammatory drugs on colorectal cancer risk.
    Cancer Res. 2018 Jun 19. pii: 0008-5472.CAN-18-0326.
    PubMed     Abstract available


    May 2018
  86. LOFFLER MW, Kowalewski DJ, Backert L, Bernhardt J, et al
    Mapping the HLA ligandome of Colorectal Cancer Reveals an Imprint of Malignant Cell Transformation.
    Cancer Res. 2018 May 22. pii: 0008-5472.CAN-17-1745.
    PubMed     Abstract available


  87. ULLMANN P, Rodriguez F, Schmitz M, Meurer SK, et al
    The microRNA-371~373 cluster represses colon cancer initiation and metastatic colonization by inhibiting the TGFBR2/ID1 signaling axis.
    Cancer Res. 2018 May 10. pii: 0008-5472.CAN-17-3003.
    PubMed     Abstract available


    April 2018
  88. WANG Q, Zhou Y, Rychahou P, Harris JW, et al
    Deptor is a novel target of Wnt/beta-catenin/c-Myc and contributes to colorectal cancer cell growth.
    Cancer Res. 2018 Apr 17. pii: 0008-5472.CAN-17-3107.
    PubMed     Abstract available


  89. RESAR L, Chia L, Xian L
    Lessons from the Crypt: HMGA1-Amping up Wnt for Stem Cells and Tumor Progression.
    Cancer Res. 2018 Apr 4. pii: 0008-5472.CAN-17-3045.
    PubMed     Abstract available


  90. CASTLE PE
    Charting the Future of Cancer Health Disparities Research-Letter.
    Cancer Res. 2018;78:1883-1885.
    PubMed    


  91. SCHWAB A, Siddiqui A, Vazakidou ME, Napoli F, et al
    Polyol Pathway Links Glucose Metabolism to the Aggressiveness of Cancer Cells.
    Cancer Res. 2018;78:1604-1618.
    PubMed     Abstract available


  92. WALKER-SAMUEL S, Roberts TA, Ramasawmy R, Burrell JS, et al
    Investigating Low-Velocity Fluid Flow in Tumors with Convection-MRI.
    Cancer Res. 2018;78:1859-1872.
    PubMed     Abstract available


    March 2018
  93. MENG Q, Wu S, Wang Y, Xu J, et al
    MPO promoter polymorphism rs2333227 enhances malignant phenotypes of colorectal cancer by altering the binding affinity of AP-2alpha.
    Cancer Res. 2018 Mar 14. pii: 0008-5472.CAN-17-2538.
    PubMed     Abstract available


  94. PAQUET-FIFIELD S, Koh SL, Cheng L, Beyit LM, et al
    Tight junction protein claudin-2 promotes self-renewal of human colorectal cancer stem-like cells.
    Cancer Res. 2018 Mar 6. pii: 0008-5472.CAN-17-1869.
    PubMed     Abstract available


    February 2018
  95. TOMMELEIN J, De Vlieghere E, Verset L, Melsens E, et al
    Radiotherapy-Activated Cancer-Associated Fibroblasts Promote Tumor Progression through Paracrine IGF1R Activation.
    Cancer Res. 2018;78:659-670.
    PubMed     Abstract available


  96. CHOWELL D, Napier J, Gupta R, Anderson KS, et al
    Modeling the Subclonal Evolution of Cancer Cell Populations.
    Cancer Res. 2018;78:830-839.
    PubMed     Abstract available


    January 2018
  97. LIU L, Zhang Y, Wong CC, Zhang J, et al
    RNF6 promotes colorectal cancer by activating the Wnt/beta-catenin pathway via ubiquitination of TLE3.
    Cancer Res. 2018 Jan 26. pii: 0008-5472.CAN-17-2683.
    PubMed     Abstract available


  98. YAN TT, Ren LL, Shen CQ, Wang ZH, et al
    MicroRNA-508 defines the stem-like/mesenchymal subtype in colorectal cancer.
    Cancer Res. 2018 Jan 26. pii: 0008-5472.CAN-17-2101.
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  99. YANG X, Wang Z, Li X, Liu B, et al
    SHMT2 Desuccinylation by SIRT5 Drives Cancer Cell Proliferation.
    Cancer Res. 2018;78:372-386.
    PubMed     Abstract available


    December 2017
  100. HANKEY WC, McIlhatton MA, Ebede K, Kennedy B, et al
    Mutational mechanisms that activate Wnt signaling and predict outcomes in colorectal cancer patients.
    Cancer Res. 2017 Dec 6. pii: 0008-5472.CAN-17-1357.
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  101. Correction: miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4.
    Cancer Res. 2017;77:6788.
    PubMed    


  102. YAEGER R, Yao Z, Hyman DM, Hechtman JF, et al
    Mechanisms of Acquired Resistance to BRAF V600E Inhibition in Colon Cancers Converge on RAF Dimerization and Are Sensitive to Its Inhibition.
    Cancer Res. 2017;77:6513-6523.
    PubMed     Abstract available


    November 2017
  103. EMERSON MA, Banegas MP, Chawla N, Achacoso N, et al
    Disparities in Prostate, Lung, Breast, and Colorectal Cancer Survival and Comorbidity Status among Urban American Indians and Alaskan Natives.
    Cancer Res. 2017 Nov 29. pii: 0008-5472.CAN-17-0429.
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  104. YAU EH, Kummetha IR, Lichinchi G, Tang R, et al
    Genome-Wide CRISPR Screen for Essential Cell Growth Mediators in Mutant KRAS Colorectal Cancers.
    Cancer Res. 2017;77:6330-6339.
    PubMed     Abstract available



  105. Correction: A Squalene-Based Nanomedicine for Oral Treatment of Colon Cancer.
    Cancer Res. 2017;77:6048.
    PubMed    


    October 2017
  106. LULLA AR, Slifker MJ, Zhou Y, Lev A, et al
    miR-6883 family miRNAs target CDK4/6 to induce G1 phase cell cycle arrest in colon cancer cells.
    Cancer Res. 2017 Oct 23. pii: canres.1767.2017.
    PubMed     Abstract available


  107. KIM SY, Jung JH, Lee HJ, Soh H, et al
    [18F]fluorothymidine positron emission tomography informs the synergistic efficacy of capecitabine and trifluridine/tipiracil in colon cancer.
    Cancer Res. 2017 Oct 20. pii: canres.1406.2017.
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  108. HUANG S, Fantini D, Merrill B, Bagchi S, et al
    DDB2 is a Novel Regulator of Wnt-Signaling in Colon Cancer.
    Cancer Res. 2017 Oct 11. pii: canres.1570.2017.
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  109. TANG YC, Yuwen H, Wang K, Bruno PM, et al
    Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis.
    Cancer Res. 2017;77:5272-5286.
    PubMed     Abstract available


    September 2017
  110. KIDDER BL, He R, Wangsa D, Padilla-Nash HM, et al
    SMYD5 controls heterochromatin and chromosome integrity during embryonic stem cell differentiation.
    Cancer Res. 2017 Sep 26. pii: canres.0828.2017.
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  111. ZHOU X, Geng L, Wang D, Yi H, et al
    R-Spondin1/LGR5 Activates TGFbeta Signaling and Suppresses Colon Cancer Metastasis.
    Cancer Res. 2017 Sep 22. pii: canres.0219.2017.
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  112. KATHER JN, Poleszczuk J, Suarez-Carmona M, Krisam J, et al
    In silico modeling of immunotherapy and stroma-targeting therapies in human colorectal cancer.
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  113. LI P, Wuthrick E, Rappaport JA, Kraft C, et al
    GUCY2C Signaling Opposes the Acute Radiation-Induced GI Syndrome.
    Cancer Res. 2017;77:5095-5106.
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  114. TAKADA M, Zhang W, Suzuki A, Kuroda TS, et al
    FBW7 Loss Promotes Chromosomal Instability and Tumorigenesis via Cyclin E1/CDK2-Mediated Phosphorylation of CENP-A.
    Cancer Res. 2017;77:4881-4893.
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    August 2017
  115. ZHAO Y, Ting KK, Li J, Cogger VC, et al
    Targeting Vascular Endothelial-Cadherin in Tumor-Associated Blood Vessels Promotes T-cell-Mediated Immunotherapy.
    Cancer Res. 2017;77:4434-4447.
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  116. MARELLI G, Erreni M, Anselmo A, Taverniti V, et al
    Heme-oxygenase-1 Production by Intestinal CX3CR1+ Macrophages Helps to Resolve Inflammation and Prevents Carcinogenesis.
    Cancer Res. 2017;77:4472-4485.
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    July 2017
  117. JERMYN M, Mercier J, Aubertin K, Desroches J, et al
    Highly Accurate Detection of Cancer In Situ with Intraoperative, Label-Free, Multimodal Optical Spectroscopy.
    Cancer Res. 2017;77:3942-3950.
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    May 2017
  118. VISWANATHAN V, Damle S, Zhang T, Opdenaker LM, et al
    An miRNA expression signature for the human colonic stem cell niche distinguishes malignant from normal epithelia.
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  119. LANG M, Berry D, Passecker K, Mesteri I, et al
    HuR Small-Molecule Inhibitor Elicits Differential Effects in Adenomatosis Polyposis and Colorectal Carcinogenesis.
    Cancer Res. 2017;77:2424-2438.
    PubMed     Abstract available


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