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COVID Reference, 5th edition, 486 pages

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  Colorectal Neoplasms

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Articles published in Clin Cancer Res

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Single Articles


    November 2020
  1. JACOBS SA, Lee JJ, George TJ, Wade JL, et al
    Neratinib plus Cetuximab in Quadruple WT (KRAS, NRAS, BRAF, PIK3CA) Metastatic Colorectal Cancer Resistant to Cetuximab or Panitumumab: NSABP FC-7, A Phase Ib Study.
    Clin Cancer Res. 2020 Nov 17. pii: 1078-0432.CCR-20-1831.
    PubMed     Abstract available


  2. JIFFRY J, Thavornwatanayong T, Rao D, Fogel EJ, et al
    Oncolytic reovirus (pelareorep) induces autophagy in KRAS-mutated colorectal cancer.
    Clin Cancer Res. 2020 Nov 9. pii: 1078-0432.CCR-20-2385.
    PubMed     Abstract available


    October 2020
  3. LOREE JM, Dowers A, Tu D, Jonker D, et al
    Expanded low allele frequency RAS and BRAF V600E testing in metastatic colorectal cancer as predictive biomarkers for cetuximab in the randomized CO.17 trial.
    Clin Cancer Res. 2020 Oct 21. pii: 1078-0432.CCR-20-2710.
    PubMed     Abstract available


  4. XIE H, Mahoney DW, Foote PH, Burger KN, et al
    Novel Methylated DNA Markers in the Surveillance of Colorectal Cancer Recurrence.
    Clin Cancer Res. 2020 Oct 7. pii: 1078-0432.CCR-20-2589.
    PubMed     Abstract available


  5. MALLA SB, Fisher D, Domingo E, Blake A, et al
    In-depth clinical and biological exploration of DNA Damage Immune Response (DDIR) as a biomarker for oxaliplatin use in colorectal cancer.
    Clin Cancer Res. 2020 Oct 7. pii: 1078-0432.CCR-20-3237.
    PubMed     Abstract available


    September 2020
  6. MAITLAND ML, Wilkerson J, Karovic S, Zhao B, et al
    Enhanced detection of treatment effects on metastatic colorectal cancer with volumetric CT measurements for tumor burden growth rate evaluation.
    Clin Cancer Res. 2020 Sep 28. pii: 1078-0432.CCR-20-1493.
    PubMed     Abstract available


  7. NUSRAT M
    Response to anti-PD-1 in microsatellite stable colorectal cancer: a STAT need.
    Clin Cancer Res. 2020 Sep 21. pii: 1078-0432.CCR-20-2901.
    PubMed     Abstract available


  8. INNOCENTI F, Sibley AB, Patil SA, Etheridge AS, et al
    Genomic analysis of germline variation associated with survival of colorectal cancer patients treated with chemotherapy plus biologics in CALGB/SWOG 80405 (Alliance).
    Clin Cancer Res. 2020 Sep 21. pii: 1078-0432.CCR-20-2021.
    PubMed     Abstract available


  9. STAHLER A, Stintzing S, Modest DP, Ricard I, et al
    Amphiregulin expression is a predictive biomarker for EGFR inhibition in metastatic colorectal cancer: combined analysis of three randomized trials.
    Clin Cancer Res. 2020 Sep 17. pii: 1078-0432.CCR-20-2748.
    PubMed     Abstract available


  10. DE GOOYER JM, Elekonawo FMK, Bos DL, van der Post RS, et al
    Multimodal CEA-targeted image-guided colorectal cancer surgery using 111In-labeled SGM-101.
    Clin Cancer Res. 2020 Sep 8. pii: 1078-0432.CCR-20-2255.
    PubMed     Abstract available


    July 2020
  11. KAWAZOE A, Kuboki Y, Shinozaki E, Hara H, et al
    Multicenter phase 1/2 Trial of napabucasin and pembrolizumab in patients with metastatic colorectal cancer (EPOC1503/SCOOP Trial).
    Clin Cancer Res. 2020 Jul 21. pii: 1078-0432.CCR-20-1803.
    PubMed     Abstract available


  12. RANDON G, Pagani F, Pietrantonio F
    MGMT Promoter Methylation as a Target In Metastatic Colorectal Cancer: Rapid Turnover and Use of Folates Alter its Study-Response.
    Clin Cancer Res. 2020;26:3495.
    PubMed    


  13. OTTAIANO A, Caraglia M
    MGMT Promoter Methylation as a Target In Metastatic Colorectal Cancer: Rapid Turnover and Use of Folates Alter its Study-Letter.
    Clin Cancer Res. 2020;26:3493-3494.
    PubMed    


    June 2020
  14. CHU JE, Johnson B, Kugathasan L, Morris VK, et al
    Population-based screening for BRAF (V600E) in metastatic colorectal cancer reveals increased prevalence and poor prognosis.
    Clin Cancer Res. 2020 Jun 22. pii: 1078-0432.CCR-20-1024.
    PubMed     Abstract available


    May 2020
  15. VAYRYNEN JP, Lau MC, Haruki K, Vayrynen SA, et al
    Prognostic significance of immune cell populations identified by machine learning in colorectal cancer using routine hematoxylin & eosin stained sections.
    Clin Cancer Res. 2020 May 21. pii: 1078-0432.CCR-20-0071.
    PubMed     Abstract available


  16. MCCUAIG S, Barras D, Mann E, Friedrich M, et al
    The interleukin 22 pathway interacts with mutant KRAS to promote poor prognosis in colon cancer.
    Clin Cancer Res. 2020 May 19. pii: 1078-0432.CCR-19-1086.
    PubMed     Abstract available


    April 2020
  17. LAKINS MA, Koers A, Giambalvo R, Munoz-Olaya J, et al
    FS222, a CD137/PD-L1 tetravalent bispecific antibody exhibits low toxicity and anti-tumor activity in colorectal cancer models.
    Clin Cancer Res. 2020 Apr 28. pii: 1078-0432.CCR-19-2958.
    PubMed     Abstract available


  18. KIM RD, Azad NS, Morse MA, Poplin E, et al
    Phase II Study of Ensituximab, a Novel Chimeric Monoclonal Antibody, in Adults with Unresectable, Metastatic Colorectal Cancer.
    Clin Cancer Res. 2020 Apr 17. pii: 1078-0432.CCR-20-0426.
    PubMed     Abstract available


  19. BRUUN J, Kryeziu K, Eide PW, Moosavi SH, et al
    Patient-derived organoids from multiple colorectal cancer liver metastases reveal moderate intra-patient pharmacotranscriptomic heterogeneity.
    Clin Cancer Res. 2020 Apr 16. pii: 1078-0432.CCR-19-3637.
    PubMed     Abstract available


  20. MORRIS VK, Bekaii-Saab T
    Improvements in Clinical Outcomes for BRAFV600E-mutant Metastatic Colorectal Cancer.
    Clin Cancer Res. 2020 Apr 6. pii: 1078-0432.CCR-19-3809.
    PubMed     Abstract available


    March 2020
  21. MAX MA X, Bendell JC, Hurwitz HI, Ju C, et al
    Disease Monitoring Using Post-Induction Circulating Tumor DNA Analysis Following First-Line Therapy in Patients with Metastatic Colorectal Cancer.
    Clin Cancer Res. 2020 Mar 27. pii: 1078-0432.CCR-19-1209.
    PubMed     Abstract available


    February 2020
  22. YOO SY, Park HE, Kim JH, Wen X, et al
    Whole-Slide Image Analysis Reveals Quantitative Landscape of Tumor-Immune Microenvironment in Colorectal Cancers.
    Clin Cancer Res. 2020;26:870-881.
    PubMed     Abstract available


  23. CAPDEVILA J, Arques O, Hernandez Mora JR, Matito J, et al
    Epigenetic EGFR Gene Repression Confers Sensitivity to Therapeutic BRAFV600E Blockade in Colon Neuroendocrine Carcinomas.
    Clin Cancer Res. 2020;26:902-909.
    PubMed     Abstract available


  24. MIDDLETON G, Yang Y, Campbell CD, Andre T, et al
    BRAF-mutant Transcriptional Subtypes Predict Outcome of Combined BRAF, MEK, and EGFR Blockade with Dabrafenib, Trametinib, and Panitumumab in Patients with Colorectal Cancer.
    Clin Cancer Res. 2020 Feb 11. pii: 1078-0432.CCR-19-3579.
    PubMed     Abstract available


    January 2020
  25. KHAKOO S, Carter PD, Brown G, Valeri N, et al
    MRI Tumor Regression Grade and Circulating Tumor DNA as Complementary Tools to Assess Response and Guide Therapy Adaptation in Rectal Cancer.
    Clin Cancer Res. 2020;26:183-192.
    PubMed     Abstract available


    November 2019
  26. PIETRANTONIO F, Lobefaro R, Antista M, Lonardi S, et al
    Capecitabine and temozolomide versus FOLFIRI in RAS mutated, MGMT methylated metastatic colorectal cancer.
    Clin Cancer Res. 2019 Nov 18. pii: 1078-0432.CCR-19-3024.
    PubMed     Abstract available


  27. DATTA J, Smith JJ, Chatila WK, McAuliffe JC, et al
    Co-Altered Ras/B-raf and TP53 is Associated with Extremes of Survivorship and Distinct Patterns of Metastasis in Metastatic Colorectal Cancer Patients.
    Clin Cancer Res. 2019 Nov 12. pii: 1078-0432.CCR-19-2390.
    PubMed     Abstract available


    October 2019
  28. WANG S, Huang J, Li C, Zhao L, et al
    MAP9 loss triggers chromosomal instability, initiates colorectal tumorigenesis and is associated with poor survival of colorectal cancer patients.
    Clin Cancer Res. 2019 Oct 29. pii: 1078-0432.CCR-19-1611.
    PubMed     Abstract available


    September 2019
  29. YUAN C, Sato K, Hollis BW, Zhang S, et al
    Plasma 25-Hydroxyvitamin D Levels and Survival in Patients with Advanced or Metastatic Colorectal Cancer: Findings from CALGB/SWOG 80405 (Alliance).
    Clin Cancer Res. 2019 Sep 23. pii: 1078-0432.CCR-19-0877.
    PubMed     Abstract available


  30. YAEGER R, Kotani D, Mondaca S, Parikh AR, et al
    Response to Anti-EGFR Therapy in Patients with BRAF non-V600-Mutant Metastatic Colorectal Cancer.
    Clin Cancer Res. 2019 Sep 12. pii: 1078-0432.CCR-19-2004.
    PubMed     Abstract available


  31. LLOSA NJ, Luber B, Tam AJ, Smith KN, et al
    Intratumoral Adaptive Immunosuppression and Type 17 Immunity in Mismatch Repair Proficient Colorectal Tumors.
    Clin Cancer Res. 2019;25:5250-5259.
    PubMed     Abstract available


    August 2019
  32. ANGELL HK, Bruni D, Barrett JC, Herbst R, et al
    The Immunoscore: Colon Cancer and Beyond.
    Clin Cancer Res. 2019 Aug 14. pii: 1078-0432.CCR-18-1851.
    PubMed     Abstract available


  33. LAZZARI L, Corti G, Picco G, Isella C, et al
    Patient-derived xenografts and matched cell lines identify pharmacogenomic vulnerabilities in colorectal cancer.
    Clin Cancer Res. 2019 Aug 2. pii: 1078-0432.CCR-18-3440.
    PubMed     Abstract available


    July 2019
  34. LEE DW, Han SW, Bae JM, Jang H, et al
    Tumor Mutation Burden and Prognosis in Colorectal Cancer Patients Treated with Adjuvant Fluoropyrimidine and Oxaliplatin.
    Clin Cancer Res. 2019 Jul 8. pii: 1078-0432.CCR-19-1105.
    PubMed     Abstract available


  35. WILLIS JA, Overman MJ, Vilar E
    Mismatch repair-proficient colorectal cancer: finding the right TiME to respond.
    Clin Cancer Res. 2019 Jul 1. pii: 1078-0432.CCR-19-1447.
    PubMed     Abstract available


    June 2019
  36. LIEU CH, Golemis EA, Serebriiskii IG, Newberg JY, et al
    Comprehensive Genomic Landscapes in Early and Later Onset Colorectal Cancer.
    Clin Cancer Res. 2019 Jun 26. pii: 1078-0432.CCR-19-0899.
    PubMed     Abstract available


  37. FREIRE VALLS A, Knipper K, Giannakouri E, Sarachaga V, et al
    VEGFR1(+) metastasis-associated macrophages contribute to metastatic angiogenesis and influence colorectal cancer patient outcome.
    Clin Cancer Res. 2019 Jun 25. pii: 1078-0432.CCR-18-2123.
    PubMed     Abstract available


    April 2019
  38. PISKOL R, Huw LY, Sergin I, Klijn C, et al
    A Clinical Applicable Gene Expression Classifier Reveals Intrinsic and Extrinsic Contributions to Consensus Molecular Subtypes in Primary and Metastatic Colon Cancer.
    Clin Cancer Res. 2019 Apr 19. pii: 1078-0432.CCR-18-3032.
    PubMed     Abstract available


  39. FENG Q, Chang W, Mao Y, He G, et al
    Tumor-associated macrophages as prognostic and predictive biomarkers for postoperative adjuvant chemotherapy in patients with stage II colon cancer.
    Clin Cancer Res. 2019 Apr 15. pii: 1078-0432.CCR-18-2076.
    PubMed     Abstract available


  40. WANG XC, Yue X, Zhang R, Liu TY, et al
    Genome-wide RNAi screening identifies RFC4 as a factor that mediates radioresistance in colorectal cancer by facilitating non-homologous end joining repair.
    Clin Cancer Res. 2019 Apr 12. pii: 1078-0432.CCR-18-3735.
    PubMed     Abstract available


  41. DIAZ-MAROTO NG, Sanz-Pamplona R, Berdiel-Acer M, Cimas FJ, et al
    Non-canonical TGFb pathway relieves the blockade of IL-1b/TGFb-mediated crosstalk between tumour and stroma: TGFBR1TAK1 inhibition in colorectal cancer.
    Clin Cancer Res. 2019 Apr 12. pii: 1078-0432.CCR-18-3957.
    PubMed     Abstract available


  42. SCHIRRIPA M, Biason P, Lonardi S, Pella N, et al
    Class 1, 2 and 3 BRAF mutated metastatic colorectal cancer: a detailed clinical, pathological and molecular characterization.
    Clin Cancer Res. 2019 Apr 9. pii: 1078-0432.CCR-19-0311.
    PubMed     Abstract available


  43. ANANDAPPA G, Lampis A, Cunningham D, Khan KH, et al
    MicroRNA 31-3p expression and benefit from anti-EGFR inhibitors in metastatic colorectal cancer patients enrolled in the prospective phase II PROSPECT-C trial.
    Clin Cancer Res. 2019 Apr 5. pii: 1078-0432.CCR-18-3769.
    PubMed     Abstract available


  44. MORRIS VK
    Circulating Tumor DNA in Advanced Anal Cancer: A Blood Biomarker Goes Viral.
    Clin Cancer Res. 2019;25:2030-2032.
    PubMed     Abstract available


    February 2019
  45. SIRAVEGNA G, Sartore-Bianchi A, Nagy RJ, Raghav K, et al
    Plasma HER2 (ERBB2) copy number predicts response to HER2-targeted therapy in metastatic colorectal cancer.
    Clin Cancer Res. 2019 Feb 26. pii: 1078-0432.CCR-18-3389.
    PubMed     Abstract available


    January 2019
  46. OGAWA R, Yamamoto T, Hirai H, Hanada K, et al
    Loss of SMAD4 promotes colorectal cancer progression by recruiting tumor-associated neutrophils via CXCL1/8-CXCR2 axis.
    Clin Cancer Res. 2019 Jan 31. pii: 1078-0432.CCR-18-3684.
    PubMed     Abstract available


  47. TOKUNAGA R, Xiu J, Johnston C, Goldberg RM, et al
    Molecular profiling of appendiceal adenocarcinoma and comparison with right-sided and left-sided colorectal cancer.
    Clin Cancer Res. 2019 Jan 28. pii: 1078-0432.CCR-18-3388.
    PubMed     Abstract available


    December 2018
  48. WASSERMAN I, Lee LH, Ogino S, Marco MR, et al
    SMAD4 loss in colorectal cancer patients correlates with recurrence, loss of immune infiltrate, and chemoresistance.
    Clin Cancer Res. 2018 Dec 26. pii: 1078-0432.CCR-18-1726.
    PubMed     Abstract available


  49. YANG W, Ma Y, Smith-Warner SA, Song M, et al
    Calcium intake and survival after colorectal cancer diagnosis.
    Clin Cancer Res. 2018 Dec 13. pii: 1078-0432.CCR-18-2965.
    PubMed     Abstract available


    November 2018
  50. PEETERS M, Price T, Boedigheimer M, Kim TW, et al
    Evaluation of Emergent Mutations in Circulating Cell-Free DNA and Clinical Outcomes in Patients With Metastatic Colorectal Cancer Treated With Panitumumab in the ASPECCT Study.
    Clin Cancer Res. 2018 Nov 28. pii: 1078-0432.CCR-18-2072.
    PubMed     Abstract available


  51. PARK SY, Kim JY, Choi JH, Kim JH, et al
    Inhibition of LEF1-mediated DCLK1 by Niclosamide Attenuates Colorectal Cancer Stemness.
    Clin Cancer Res. 2018 Nov 16. pii: 1078-0432.CCR-18-1232.
    PubMed     Abstract available


    October 2018
  52. LEE LY, Woolley CE, Starkey T, Biswas S, et al
    SERUM- AND GLUCOCORTICOID-INDUCED KINASE SGK1 DIRECTLY PROMOTES THE DIFFERENTIATION OF COLORECTAL CANCER CELLS AND RESTRAINS METASTASIS.
    Clin Cancer Res. 2018 Oct 15. pii: 1078-0432.CCR-18-1033.
    PubMed     Abstract available


    September 2018
  53. PARIKH AR, Lee FC, Yau L, Koh H, et al
    MAVERICC, a randomized, biomarker-stratified, phase 2 study of mFOLFOX6-bevacizumab vs FOLFIRI-bevacizumab as first-line chemotherapy in metastatic colorectal cancer.
    Clin Cancer Res. 2018 Sep 17. pii: 1078-0432.CCR-18-1221.
    PubMed     Abstract available


    August 2018
  54. LAURENT-PUIG P, Grisoni ML, Heinemann V, Liebaert F, et al
    Validation of miR-31-3p Expression to Predict Cetuximab Efficacy When Used as First-Line Treatment in RAS Wild-Type Metastatic Colorectal Cancer.
    Clin Cancer Res. 2018 Aug 14. pii: 1078-0432.CCR-18-1324.
    PubMed     Abstract available


  55. LEE V, Wang JS, Zahurak ML, Gootjes EC, et al
    A phase I trial of a guadecitabine (SGI-110) and irinotecan in metastatic colorectal cancer patients previously exposed to irinotecan.
    Clin Cancer Res. 2018 Aug 10. pii: 1078-0432.CCR-18-0421.
    PubMed     Abstract available


    June 2018
  56. PAAUWE M, Schoonderwoerd MJ, Helderman RFCPA, Harryvan TJ, et al
    Endoglin expression on cancer-associated fibroblasts regulates invasion and stimulates colorectal cancer metastasis.
    Clin Cancer Res. 2018 Jun 26. pii: 1078-0432.CCR-18-0329.
    PubMed     Abstract available


  57. GALLOIS C, Taieb J, Le Corre D, Le Malicot K, et al
    Prognostic value of methylator phenotype in stage III colon cancer treated with oxaliplatin-based adjuvant chemotherapy.
    Clin Cancer Res. 2018 Jun 19. pii: 1078-0432.CCR-18-0866.
    PubMed     Abstract available


  58. BIAN Z, Zhang J, Li M, Feng Y, et al
    LncRNA-FEZF1-AS1 promotes tumor proliferation and metastasis in colorectal cancer by regulating PKM2 signaling.
    Clin Cancer Res. 2018 Jun 18. pii: 1078-0432.CCR-17-2967.
    PubMed     Abstract available


  59. KIM TW, Peeters M, Thomas AL, Gibbs P, et al
    Impact of Emergent Circulating Tumor DNA RAS Mutation in Panitumumab-Treated Chemoresistant Metastatic Colorectal Cancer.
    Clin Cancer Res. 2018 Jun 13. pii: 1078-0432.CCR-17-3377.
    PubMed     Abstract available


    May 2018
  60. NODA M, Okayama H, Tachibana K, Sakamoto W, et al
    Glycosyltransferase gene expression identifies a poor prognostic colorectal cancer subtype associated with mismatch repair deficiency and incomplete glycan synthesis.
    Clin Cancer Res. 2018 May 29. pii: 1078-0432.CCR-17-3533.
    PubMed     Abstract available


  61. TOWNSEND A, Tebbutt NC, Karapetis CS, Cooper P, et al
    PHASE IB/II STUDY OF SECOND LINE THERAPY WITH PANITUMUMAB, IRINOTECAN AND EVEROLIMUS (PIE) IN KRAS WILD TYPE METASTATIC COLORECTAL CANCER.
    Clin Cancer Res. 2018 May 8. pii: 1078-0432.CCR-17-3590.
    PubMed     Abstract available


    April 2018
  62. RODRIGUEZ J, Vicent S, Chopitea A, Ponz-Sarvise M, et al
    Adjuvant therapy for colon cancer: genes, genes... and the patient in the center.
    Clin Cancer Res. 2018 Apr 20. pii: 1078-0432.CCR-18-0818.
    PubMed     Abstract available


    March 2018
  63. TOLEDO RA, Garralda E, Mitsi M, Pons T, et al
    Exome sequencing of plasma DNA portrays the mutation landscape of colorectal cancer and discovers mutated VEGFR2 receptors as modulators of anti-angiogenic therapies.
    Clin Cancer Res. 2018 Mar 27. pii: 1078-0432.CCR-18-0103.
    PubMed     Abstract available


  64. MURCIA O, Jover R, Egoavil CM, Juarez M, et al
    TFAP2E Methylation and Expression Status Does Not Predict Response to 5FU-based Chemotherapy in Colorectal Cancer.
    Clin Cancer Res. 2018 Mar 13. pii: 1078-0432.CCR-17-2940.
    PubMed     Abstract available


  65. KANDIMALLA R, Gao F, Matsuyama T, Ishikawa T, et al
    Genome-wide discovery and identification of a novel miRNA signature for recurrence prediction in stage II and III colorectal cancer.
    Clin Cancer Res. 2018 Mar 7. pii: 1078-0432.CCR-17-3236.
    PubMed     Abstract available


  66. HILL AG, Findlay M, Burge M, Jackson C, et al
    Phase II study of the dual EGFR/HER3 inhibitor duligotuzumab (MEHD7945A) vs. cetuximab in combination with FOLFIRI in RAS wild-type metastatic colorectal cancer.
    Clin Cancer Res. 2018 Mar 5. pii: 1078-0432.CCR-17-0646.
    PubMed     Abstract available


    February 2018
  67. MESANGE P, Bouygues A, Ferrand N, Sabbah M, et al
    Combinations of Bevacizumab and Erlotinib show activity in colorectal cancer independent of RAS status.
    Clin Cancer Res. 2018 Feb 28. pii: 1078-0432.CCR-17-3187.
    PubMed     Abstract available


  68. HAYNES J, McKee TD, Haller AC, Wang Y, et al
    Administration of Hypoxia-Activated Prodrug Evofosfamide after Adjuvant Therapy Enhances Therapeutic Outcome and Targets Cancer-Initiating Cells in Colorectal Cancer.
    Clin Cancer Res. 2018 Feb 23. pii: 1078-0432.CCR-17-1715.
    PubMed     Abstract available


  69. LI X, Wang Q, Gao X, Yu T, et al
    REGgamma controls Hippo signaling and reciprocal NF-kappaB-YAP regulation to promote colon cancer.
    Clin Cancer Res. 2018 Feb 6. pii: 1078-0432.CCR-17-2986.
    PubMed     Abstract available


  70. LAMPRECHT S, Kaller M, Schmidt EM, Blaj C, et al
    PBX3 is part of an EMT regulatory network and indicates poor outcome in colorectal cancer.
    Clin Cancer Res. 2018 Feb 1. pii: 1078-0432.CCR-17-2572.
    PubMed     Abstract available


    January 2018

  71. Correction: Prevention of Colitis and Colitis-Associated Colorectal Cancer by a Novel Polypharmacological Histone Deacetylase Inhibitor.
    Clin Cancer Res. 2018;24:499.
    PubMed    


  72. MARSHALL JF
    Targeting CDH17 in Cancer: When Blocking the Ligand Beats Blocking the Receptor?
    Clin Cancer Res. 2018;24:253-255.
    PubMed     Abstract available


    December 2017
  73. LIANG Q, Ma D, Zhu X, Wang Z, et al
    RING-finger protein 6 amplification activates JAK/STAT3 pathway by modifying SHP-1 ubiquitylation and associates with poor outcome in colorectal cancer.
    Clin Cancer Res. 2017 Dec 29. pii: 1078-0432.CCR-17-2133.
    PubMed     Abstract available


  74. DIENSTMANN R
    Tumor side as model of integrative molecular classification of colorectal cancer.
    Clin Cancer Res. 2017 Dec 21. pii: 1078-0432.CCR-17-3477.
    PubMed     Abstract available


  75. SVEEN A, Bruun J, Eide PW, Eilertsen IA, et al
    Colorectal cancer Consensus Molecular Subtypes translated to preclinical models uncover potentially targetable cancer-cell dependencies.
    Clin Cancer Res. 2017 Dec 14. pii: 1078-0432.CCR-17-1234.
    PubMed     Abstract available


  76. BERGER MD, Stintzing S, Heinemann V, Cao S, et al
    A polymorphism within the vitamin D transporter gene predicts outcome in metastatic colorectal cancer patients treated with FOLFIRI/bevacizumab or FOLFIRI/cetuximab.
    Clin Cancer Res. 2017 Dec 5. pii: 1078-0432.CCR-17-1663.
    PubMed     Abstract available


  77. ULINTZ PJ, Greenson JK, Wu R, Fearon ER, et al
    Lymph Node Metastases in Colon Cancer are Polyclonal.
    Clin Cancer Res. 2017 Dec 4. pii: 1078-0432.CCR-17-1425.
    PubMed     Abstract available


  78. CARNERO A, Lucena-Cacace A, Otero-Albiol D, Jimenez-Garcia MP, et al
    NAMPT is a Potent Oncogene in Colon Cancer Progression that Modulates Cancer Stem Cell Properties and resistance to therapy through Sirt1 and PARP.
    Clin Cancer Res. 2017 Dec 4. pii: 1078-0432.CCR-17-2575.
    PubMed     Abstract available


    November 2017
  79. LOREE JM, Pereira AA, Lam M, Willauer AN, et al
    Classifying colorectal cancer by tumor location rather than sidedness highlights a continuum in mutation profiles and Consensus Molecular Subtypes.
    Clin Cancer Res. 2017 Nov 27. pii: 1078-0432.CCR-17-2484.
    PubMed     Abstract available


    October 2017
  80. GROTHEY A, Strosberg JR, Renfro LA, Hurwitz HI, et al
    A Randomized, Double-blind, Placebo-controlled Phase 2 Study of Ontuxizumab (MORAb-004) in Patients with Chemorefractory Metastatic Colorectal Cancer.
    Clin Cancer Res. 2017 Oct 30. pii: clincanres.1558.2017.
    PubMed     Abstract available


  81. LAL N, White BS, Goussous G, Pickles OJ, et al
    KRAS mutation and Consensus Molecular Subtypes 2 and 3 are independently associated with reduced immune infiltration and reactivity in colorectal cancer.
    Clin Cancer Res. 2017 Oct 23. pii: clincanres.1090.2017.
    PubMed     Abstract available


  82. BOCCACCIO C, Luraghi P, Bigatto V, Cipriano E, et al
    A molecularly annotated model of patient-derived colon cancer stem-like cells to assess genetic and non-genetic mechanisms of resistance to anti-EGFR therapy.
    Clin Cancer Res. 2017 Oct 3. pii: clincanres.2151.2017.
    PubMed     Abstract available


    September 2017
  83. KANG DW, Lee BH, Suh YA, Choi YS, et al
    Phospholipase D1 inhibition linked to upregulation of ICAT blocks colorectal cancer growth hyperactivated by Wnt/beta-catenin and PI3K/Akt Signaling.
    Clin Cancer Res. 2017 Sep 22. pii: clincanres.0749.2017.
    PubMed     Abstract available


  84. JOUNG JG, Oh BY, Hong HK, AlKhalidi H, et al
    Tumor heterogeneity predicts metastatic potential in colorectal cancer.
    Clin Cancer Res. 2017 Sep 22. pii: clincanres.0306.2017.
    PubMed     Abstract available


  85. YIN Y, Yao S, Hu Y, Feng Y, et al
    The Immune-microenvironment Confers Chemoresistance of Colorectal Cancer through Macrophage-derived IL-6.
    Clin Cancer Res. 2017 Sep 19. pii: clincanres.1283.2017.
    PubMed     Abstract available


  86. BARTOLOME RA, Aizpurua C, Jaen M, Torres S, et al
    Monoclonal antibodies directed against cadherin RGD exhibit therapeutic activity against melanoma and colorectal cancer metastasis.
    Clin Cancer Res. 2017 Sep 15. pii: clincanres.1444.2017.
    PubMed     Abstract available


  87. JIAO HL, Ye YP, Yang RW, Sun HY, et al
    Down-regulation of SAFB sustains the NF-kappaB pathway by targeting TAK1 during the progression of colorectal cancer.
    Clin Cancer Res. 2017 Sep 14. pii: clincanres.0747.2017.
    PubMed     Abstract available


    March 2017
  88. PAKISH JB, Zhang Q, Chen Z, Liang H, et al
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