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Colorectal Neoplasms

Free Subscription 25.08.2025 2 Ann Oncol 3 Ann Surg Oncol 2 BMC Cancer 4 BMC Gastroenterol 4 Br J Cancer 2 Cancer 1 Cancer Treat Res 1 Clin Cancer Res 1 Clin Res Hepatol Gastroenterol 4 Dis Colon Rectum 4 Eur J Cancer 1 Gastroenterology 3 Gastrointest Endosc 1 Gut 3 Int J Cancer 8 Int J Colorectal Dis 1 J Am Coll Surg 6 J Natl Cancer Inst 1 J Surg Oncol 2 Oncogene 1 PLoS Genet

Retrieve available abstracts of this week’s articles: HTML format

Single Articles

Ann Oncol

1. GERMANI MM, Heinemann V, Rossini D, Fischer von Weikersthal L, et al
   Risk of disease progression in the first-line therapy of metastatic colorectal cancer to guide disease re-assessments - analysis of eleven trials by AIO and GONO.
   Ann Oncol. 2025 Aug 19:S0923-7534(25)00921-4. doi: 10.1016/j.annonc.2025.
   PubMed         Abstract available
   
   
2. BAROT S, Liljegren A, Nordenvall C, Blom J, et al
   Incidence Trends and Long-Term Survival in Early-Onset Colorectal Cancer: A Nationwide Swedish Study.
   Ann Oncol. 2025 Aug 13:S0923-7534(25)00920-2. doi: 10.1016/j.annonc.2025.
   PubMed         Abstract available
   
   

   
   Ann Surg Oncol

3. NAKAMICHI N, Shiozaki A, Kosuga T, Shimizu H, et al
   The Function and Clinical Significance of TRPV2 in Human Colon Cancer.
   Ann Surg Oncol. 2025 Aug 19. doi: 10.1245/s10434-025-18083.
   PubMed         Abstract available
   
   
4. NIE Y, Fujiyama Y, Shibaki S, Okamoto R, et al
   SPARC Induces COL1A1/COL3A1 Expressions Representing Aggressive Molecular Cancer-Associated Fibroblasts Signatures and CSF1-Mediated Cancer Invasion in Colorectal Cancer.
   Ann Surg Oncol. 2025 Aug 20. doi: 10.1245/s10434-025-18039.
   PubMed         Abstract available
   
   
5. NIE Y, Kumamoto Y, Yamashita K
   ASO Author Reflections: Cancer Stroma and SPARC are Involved in the Molecular Mechanisms of Poor Prognosis in Colorectal Cancer.
   Ann Surg Oncol. 2025 Aug 23. doi: 10.1245/s10434-025-18111.
   PubMed        
   
   

   
   BMC Cancer

6. CHA Y, Cho SH, Park EY, Lee DE, et al
   Platform study of circulating tumor DNA directed adjuvant chemotherapy in colon cancer (CLAUDIA colon cancer, KCSG CO22-12).
   BMC Cancer. 2025;25:1373.
   PubMed        
   
   
7. XIA L, Wang J, Gao J, Cui X, et al
   Integrative multi-omics analysis identifies key genes and colocalized signals associated with colorectal cancer risk.
   BMC Cancer. 2025;25:1372.
   PubMed        
   
   

   
   BMC Gastroenterol

8. ZHONG Y, Wu T, Khan NU
   Association between GLP-1 receptor agonists as a class and colorectal cancer risk: a meta-analysis of retrospective cohort studies.
   BMC Gastroenterol. 2025;25:614.
   PubMed         Abstract available
   
   
9. YUAN T, Jia G, Cao W, Chen H, et al
   The prognostic value of indoleamine 2,3-dioxygenase in colorectal cancer: a systematic review and meta-analysis.
   BMC Gastroenterol. 2025;25:603.
   PubMed         Abstract available
   
   
10. BAKER FA, Gal O, Tatour M, Ovadia B, et al
    Serrated polyps in colorectal cancer prevention: prevalence, characteristics and clinical insights from a large retrospective cohort study.
    BMC Gastroenterol. 2025;25:590.
    PubMed         Abstract available
    
    
11. KHADER M, Delgado JS, Artoul R, Shafrir A, et al
    Insights from age-stratified endoscopic detection metrics support initiating colorectal cancer screening at age 45.
    BMC Gastroenterol. 2025;25:597.
    PubMed         Abstract available
    
    

    
    Br J Cancer

12. TOH Y, Wu L, Tu J, Liang Z, et al
    Anti-tumor activity of camptothecin analog conjugate of an RSPO4-based peptibody targeting LGR4/5/6 in preclinical models of colorectal cancer.
    Br J Cancer. 2025 Aug 18. doi: 10.1038/s41416-025-03121.
    PubMed         Abstract available
    
    
13. BARLOW M, Messenger D, Preece R, Prowse A, et al
    The diagnostic accuracy of the faecal immunochemical test for the detection of early-onset colorectal cancer: an age-stratified analysis in South West England.
    Br J Cancer. 2025 Aug 22. doi: 10.1038/s41416-025-03154.
    PubMed         Abstract available
    
    
14. ZHANG D, Yang S, Xu H, Chen Z, et al
    The novel role of DUSP4 in suppressing ferroptosis and promoting cytotoxicity of CD8(+) T cells in MSI colorectal cancer.
    Br J Cancer. 2025 Aug 22. doi: 10.1038/s41416-025-03119.
    PubMed         Abstract available
    
    
15. GALMARINI CM, Zamora R, Gomez Del Campo P, Del Castillo-Izquierdo J, et al
    PROCC: a predictive score to identify KRAS wild type metastatic colorectal cancer patients who are likely to obtain survival benefit from panitumumab treatment.
    Br J Cancer. 2025 Aug 20. doi: 10.1038/s41416-025-03157.
    PubMed         Abstract available
    
    

    
    Cancer

16. NIERENGARTEN MB
    Colorectal cancer treatments show promise: Studies find longer progression-free survival and a potential relative reduction in the risk of death with treatment advances.
    Cancer. 2025;131:e70000.
    PubMed        
    
    
17. STEVENS SX, Gyawali B
    CodeBreaK or code blue? Assessing sotorasib's vital signs in metastatic colorectal cancer.
    Cancer. 2025;131:e70056.
    PubMed         Abstract available
    
    

    
    Cancer Treat Res

18. TEYMOURI F, Brar G
    Colorectal Cancers and Immunotherapy.
    Cancer Treat Res. 2025;129:83-102.
    PubMed         Abstract available
    
    

    
    Clin Cancer Res

19. MICHAEL M, Wong R, Gill S, Strickland AH, et al
    The Ave-Rec Trial: Phase II Trial of PDL1/PD1 Blockade with Avelumab after Chemoradiotherapy for Locally Advanced Resectable T3B-4/N1-2 Rectal Cancer.
    Clin Cancer Res. 2025;31:3452-3462.
    PubMed         Abstract available
    
    

    
    Clin Res Hepatol Gastroenterol

20. BESSON A, Gallois C, Lepere C, Netter J, et al
    Cardiac metastasis of colorectal cancer: a case report and review of literature.
    Clin Res Hepatol Gastroenterol. 2025 Aug 14:102669.
    PubMed        
    
    

    
    Dis Colon Rectum

21. GUPTA V, Mor A, Mundhada RO, Kazi MK, et al
    Textbook Outcomes of Minimally Invasive Total Mesorectal Excision: A Composite Tool to Assess and Compare Outcomes for Benchmarking.
    Dis Colon Rectum. 2025;68:1042-1051.
    PubMed         Abstract available
    
    
22. REZENDE DT, Kawaguti FS, Kimura CMS, Nahas CSR, et al
    Risk Factors for Stricture After Endoscopic Submucosal Dissection of Large Rectal Neoplasms.
    Dis Colon Rectum. 2025;68:1112-1119.
    PubMed         Abstract available
    
    
23. FRIEDMAN G, Specht K
    Robotic Transanal Minimally Invasive Surgery With da Vinci Single-Port Platform and Single-Port Access Port.
    Dis Colon Rectum. 2025;68:e1783-e1787.
    PubMed         Abstract available
    
    
24. STEFFENS D, Alves S, Koh CE, Ansari N, et al
    International Prospective Quality of Life in Patients With Colorectal Peritoneal Metastases Treated by Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy in the United Kingdom and Australia.
    Dis Colon Rectum. 2025;68:1074-1084.
    PubMed         Abstract available
    
    

    
    Eur J Cancer

25. ALPERT A, Shirron N, Shirman Y, Goshen-Lago T, et al
    Deciphering the proteomic landscape of pregnancy-associated colorectal cancer.
    Eur J Cancer. 2025;228:115718.
    PubMed         Abstract available
    
    
26. BATTAGLIN F, O'Neil BH, Stintzing S, Ou FS, et al
    Outcomes for FOLFIRI plus bevacizumab or cetuximab in patients treated with oxaliplatin-based adjuvant therapy: A combined analysis of FIRE-3 and CALGB/SWOG 80405 (Alliance).
    Eur J Cancer. 2025;227:115694.
    PubMed         Abstract available
    
    
27. DASARI A, Eng C, Lonardi S, Garcia-Carbonero R, et al
    Fruquintinib in less pretreated patients: Multivariate profile-matching analysis of FRESCO-2 to FRESCO.
    Eur J Cancer. 2025;227:115641.
    PubMed         Abstract available
    
    
28. LANGHEINRICH M, Gerken M, Robers G, Hansinger J, et al
    Survival benefit of adjuvant chemotherapy in elderly patients with UICC stage III colon carcinoma: A 20-year population-based German cohort study.
    Eur J Cancer. 2025;227:115583.
    PubMed         Abstract available
    
    

    
    Gastroenterology

29. SANCHEZ A, Castillo-Iturra J, Roos VH, Duenas N, et al
    Gene-Specific Detection Rate of Adenomas and Advanced Adenomas in Lynch Syndrome.
    Gastroenterology. 2025;169:663-675.
    PubMed         Abstract available
    
    

    
    Gastrointest Endosc

30. LUI TKL, Ko MKL, To EWP, Leung WK, et al
    Surveillance findings in high-risk patients after baseline computer-assisted detection colonoscopy: a propensity score matching analysis.
    Gastrointest Endosc. 2025;102:384-390.
    PubMed         Abstract available
    
    
31. ZHANG X, Dou J, Gong Y, Wu C, et al
    Performance comparison of quantitative and qualitative fecal immunochemical tests in community-based colorectal cancer screening.
    Gastrointest Endosc. 2025 Aug 18:S0016-5107(25)01912.
    PubMed         Abstract available
    
    
32. SHIRATORI Y, Ishii N, Kalloo A
    Colorectal cancer screening from the standpoint of sequential versus simultaneous approaches: insights from the Danish national screening program.
    Gastrointest Endosc. 2025;102:436-437.
    PubMed        
    
    

    
    Gut

33. FIORI ME
    Gut feeling: extracellular vesicles dictate liver's susceptibility to colorectal cancer metastasis.
    Gut. 2025 Aug 25:gutjnl-2025-336108. doi: 10.1136/gutjnl-2025-336108.
    PubMed        
    
    

    
    Int J Cancer

34. PHAM TT, Nimptsch K, Aleksandrova K, Jenab M, et al
    Circulating fatty acid binding protein 4 (FABP-4) concentrations and mortality in individuals with colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study.
    Int J Cancer. 2025 Aug 26. doi: 10.1002/ijc.70090.
    PubMed         Abstract available
    
    
35. LI T, Li Y, Yin L, Li W, et al
    Folic acid fortification and late-onset colorectal cancer risk: A systematic assessment of the worldwide evidence.
    Int J Cancer. 2025 Aug 25. doi: 10.1002/ijc.70109.
    PubMed         Abstract available
    
    
36. YUAN T, Tagscherer KE, Roth W, Bewerunge-Hudler M, et al
    Methylation-based alcohol consumption scores as prognostic biomarkers in colorectal cancer: Insights from a population-based cohort.
    Int J Cancer. 2025 Aug 19. doi: 10.1002/ijc.70086.
    PubMed         Abstract available
    
    

    
    Int J Colorectal Dis

37. HANEN G, Mohammed HE, Nasser M, Haseeb ME, et al
    Optimizing surveillance in Lynch syndrome: lesion detection and comparative performance of different colonoscopy modalities-a systematic review and network meta-analysis.
    Int J Colorectal Dis. 2025;40:175.
    PubMed         Abstract available
    
    
38. SUN Y, Tang Z, Jiang W, Wang X, et al
    Textbook outcome in low rectal cancer patients undergoing laparoscopic or open surgery: 3-year results from the multicentric LASRE Trial.
    Int J Colorectal Dis. 2025;40:177.
    PubMed         Abstract available
    
    
39. KAZI M, Pawar A, Saklani A, Bhatt A, et al
    Cytoreductive surgery for colorectal peritoneal metastasis in the era modern systemic therapies: a systematic review and meta-analysis of survival outcomes.
    Int J Colorectal Dis. 2025;40:178.
    PubMed         Abstract available
    
    
40. SHEN S, Gao H, Cao Z, Xia W, et al
    The impact of nano-carbon suspension lymph node tracing on rectal cancer surgery post-neoadjuvant therapy.
    Int J Colorectal Dis. 2025;40:182.
    PubMed         Abstract available
    
    
41. YU K, Liu P, Dong J, Zhang X, et al
    ERO1alpha regulates colon cancer progression and 5-FU resistance through the miR-451a/ARF1 axis.
    Int J Colorectal Dis. 2025;40:184.
    PubMed         Abstract available
    
    
42. SUN Y, Xu Z, Tang Y, Deng Y, et al
    Unveiling the impact of body mass index on surgical difficulty and oncological prognosis in low rectal cancer: post-hoc analysis of the LASRE trial.
    Int J Colorectal Dis. 2025;40:185.
    PubMed         Abstract available
    
    
43. CANTAGALLI MM, Sani V, Schena CA, de'Angelis N, et al
    Organ preservation in rectal cancer: opportunity within boundaries.
    Int J Colorectal Dis. 2025;40:186.
    PubMed         Abstract available
    
    
44. XU S, Gosavi R, Chung YC, Teoh W, et al
    Obesity Selectively Increases Intraoperative Risk in Left-Sided Colon Cancer Surgery: A Retrospective Cohort Study.
    Int J Colorectal Dis. 2025;40:188.
    PubMed         Abstract available
    
    

    
    J Am Coll Surg

45. KITAGUCHI D, Seow-En I, Shen MY, Ke TW, et al
    Delayed vs Immediate Coloanal Anastomosis after Total Mesorectal Excision for Low Rectal Cancer: An International Multicenter Retrospective Cohort Study.
    J Am Coll Surg. 2025;241:448-459.
    PubMed         Abstract available
    
    

    
    J Natl Cancer Inst

46. FULLER S, Alexeeff S, Caan B, Goncalves MD, et al
    Early identification of weight loss trajectories in advanced cancer and associations with survival.
    J Natl Cancer Inst. 2025;117:1729-1732.
    PubMed         Abstract available
    
    
47. DUHOKY R, Geitenbeek RTJ, Niccolo Piozzi G, Burghgraef TA, et al
    Ten years of robot-assisted versus laparoscopic total mesorectal excision for rectal cancer (short-term RESOLUTION).
    J Natl Cancer Inst. 2025;117:1614-1626.
    PubMed         Abstract available
    
    
48. TSEGAYE AT, Shing JZ, Vo JB, Kreimer AR, et al
    Racial and ethnic differences in HPV-related cancer incidence in the United States, 2001-2020.
    J Natl Cancer Inst. 2025 Apr 26:djaf107. doi: 10.1093.
    PubMed         Abstract available
    
    
49. ZAANAN A, Bergen ES, Evesque L, Meurisse A, et al
    Circulating tumor DNA driving anti-EGFR rechallenge therapy in metastatic colorectal cancer: the RASINTRO prospective multicenter study.
    J Natl Cancer Inst. 2025 Aug 20:djaf229. doi: 10.1093.
    PubMed         Abstract available
    
    
50. MAJOR A, Chou J, Lam H, Kim KE, et al
    Mortality after colorectal cancer among survivors of childhood cancer.
    J Natl Cancer Inst. 2025 Aug 21:djaf127. doi: 10.1093.
    PubMed         Abstract available
    
    
51. DOWNHAM L, Laversanne M, Perdomo S, Filho AM, et al
    Increase of early-onset colorectal cancer: a cohort effect.
    J Natl Cancer Inst. 2025 Aug 23:djaf238. doi: 10.1093.
    PubMed         Abstract available
    
    

    
    J Surg Oncol

52. VISPUTE T, Ballal DS, Kapadia R, Desouza A, et al
    Optimal Choice of Radiotherapy in Locally Advanced, Low Rectal Cancer: A Propensity Matched Analysis Comparing Short-Course Radiation With Long-Course Chemoradiation From a Tertiary Cancer Center.
    J Surg Oncol. 2025;132:384-391.
    PubMed         Abstract available
    
    

    
    Oncogene

53. STRELEZ C, Battaglin F, Perez R, Yang Y, et al
    GABAergic signaling contributes to tumor cell invasion and poor overall survival in colorectal cancer.
    Oncogene. 2025 Aug 24. doi: 10.1038/s41388-025-03546.
    PubMed         Abstract available
    
    
54. HUANG M, Qin B, Xie Z, Zhou R, et al
    RCN3 functions as a tumor promoter in colorectal cancer by modulating the GRP78-PI3K-AKT signaling pathway.
    Oncogene. 2025 Aug 23. doi: 10.1038/s41388-025-03535.
    PubMed         Abstract available
    
    

    
    PLoS Genet

55. GAUDERMAN WJ, Fu Y, Queme B, Kawaguchi E, et al
    Pathway polygenic risk scores (pPRS) for the analysis of gene-environment interaction.
    PLoS Genet. 2025;21:e1011543.
    PubMed         Abstract available
    
    

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