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90‑sec video • 4‑min audio • paper abstracts

This week, 27 April 2025:

  1. Treatment-resistant hypertension
  2. Influenza transmission
  3. Nanoplastics in human brains
  4. Malaria elimination
  5. Chikungunya vaccine

  Colorectal Neoplasms

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10.03.2025

10 Ann Surg Oncol
5 Anticancer Res
8 BMC Cancer
1 BMC Gastroenterol
2 BMJ Oncol
1 Br J Cancer
1 Cancer Lett
1 Clin Cancer Res
1 Curr Treat Options Oncol
1 Dis Colon Rectum
7 Eur J Surg Oncol
3 Gastroenterology
7 Gastrointest Endosc
1 Gut
1 Hum Pathol
1 Int J Cancer
1 Int J Colorectal Dis
1 J Natl Cancer Inst
1 J Pathol
1 PLoS One
1 Proc Natl Acad Sci U S A


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Ann Surg Oncol

  1. HANEVELT J, Brohet RM, Moons LMG, Lacle MM, et al
    ASO Visual Abstract: Risk of Lymph Node Metastasis in T2 Colon Cancer: A Nationwide Population-Based Cohort Study.
    Ann Surg Oncol. 2025 Mar 3. doi: 10.1245/s10434-025-17071.
    PubMed        

  2. MANGIERI CW, Votanopoulos KI, Shen P, Levine EA, et al
    Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) of Extraperitoneal Abdominal Disease, is it Appropriate?
    Ann Surg Oncol. 2025;32:2893-2902.
    PubMed         Abstract available

  3. WALE A, Harris H, Brown G
    Diagnostic Certainty in Characterizing Liver Lesions in Rectal Cancer: Abbreviated Liver MRI versus CT.
    Ann Surg Oncol. 2025;32:2435-2445.
    PubMed         Abstract available

  4. MAKI H, Ayabe RI, Haddad A, Nishioka Y, et al
    Associations of KRAS Point Mutations with Survival of Patients Who Underwent Curative-Intent Resection of Colorectal Liver Metastases.
    Ann Surg Oncol. 2025;32:2425-2434.
    PubMed         Abstract available

  5. SILEO A, Sassun R, Ng JC, Aboelmaaty S, et al
    Age Matters: Early-Onset Rectal Cancer Exhibits Higher Rates of Pathological Complete Response: A Retrospective Analysis of the Influence of Young Age on Treatment Success in Stage II-III Rectal Cancer.
    Ann Surg Oncol. 2025;32:2302-2307.
    PubMed         Abstract available

  6. WANG A, Zhang P, Zang J, Zhang X, et al
    Total Pelvic Exenteration with Presacral Fascia and Pelvic Musculature Excision for Pelvic Recurrence of Rectal Cancer.
    Ann Surg Oncol. 2025;32:2308-2309.
    PubMed         Abstract available

  7. COUBEAU L, Foguenne M, Marique L, Bonaccorsi Riani E, et al
    RAPID-Type Auxiliary Liver Transplantation for Unresectable Colorectal Liver Metastases: A First-Stage Surgical Video.
    Ann Surg Oncol. 2025;32:2300-2301.
    PubMed         Abstract available

  8. FALLON EA, Awiwi MO, Bhutiani N, Helmink B, et al
    Peritoneal Cancer Index Correlates with Radiographic Assessment of Colorectal Carcinomatosis.
    Ann Surg Oncol. 2025;32:2923-2931.
    PubMed         Abstract available

  9. GAN Y, Hu Q, Shen Q, Lin P, et al
    Comparison of Intratumoral and Peritumoral Deep Learning, Radiomics, and Fusion Models for Predicting KRAS Gene Mutations in Rectal Cancer Based on Endorectal Ultrasound Imaging.
    Ann Surg Oncol. 2025;32:3019-3030.
    PubMed         Abstract available

  10. TROESTER A, Weaver L, Mott SL, Welton L, et al
    Patterns of Care and Oncologic Outcomes after Pelvic Exenteration for Locally Advanced Rectal Cancer in the United States.
    Ann Surg Oncol. 2025;32:2271-2281.
    PubMed         Abstract available


    Anticancer Res

  11. SUGIYAMA M, Kasagi Y, Yokomizo R, Terashi M, et al
    Oncologic Relevance and Anal Preservation Potential of Transanal Total Mesorectal Excision for Rectal Cancer Invading Adjacent Organs.
    Anticancer Res. 2025;45:1233-1239.
    PubMed         Abstract available

  12. GOTO K, Ryu S, Imaizumi Y, Iwauchi S, et al
    Urethral Visualization Using Near-infrared Light Observation During Transanal/Perineal Total Mesorectal Excision.
    Anticancer Res. 2025;45:1241-1249.
    PubMed         Abstract available

  13. SHOJI R, Teraishi F, Kondo Y, Yoshida Y, et al
    Tailoring Neoadjuvant Therapy for Rectal Cancer: A Single-center Study of Local Recurrence Patterns.
    Anticancer Res. 2025;45:1261-1271.
    PubMed         Abstract available

  14. WEISS TS, Buechler C
    Proprotein Convertase Subtilisin/Kexin Type 9 Induction in Hypercholesterinemic Patients With Primary and Metastatic Liver Tumors.
    Anticancer Res. 2025;45:1171-1180.
    PubMed         Abstract available

  15. TERAISHI F, Yoshida Y, Shoji R, Kanaya N, et al
    Short-term Safety of Robot-assisted Rectal Surgery in Patients Aged >/=75 Years: A Single-center Retrospective Study.
    Anticancer Res. 2025;45:1291-1299.
    PubMed         Abstract available


    BMC Cancer

  16. LI Y, Zhuang M, Mei S, Hu G, et al
    Gut microbiota, immune cell, colorectal cancer association mediators: a Mendelian randomization study.
    BMC Cancer. 2025;25:396.
    PubMed         Abstract available

  17. NAVARRO-SANCHEZ A, Nieto-Vitoria MA, Lopez-Lopez JA, Martinez-Crespo JJ, et al
    Is the oral pathogen, Porphyromona gingivalis, associated to colorectal cancer?: a systematic review.
    BMC Cancer. 2025;25:395.
    PubMed         Abstract available

  18. LIU R, Tang L, Liu Y, Hu H, et al
    Causal relationship between immune cell signatures and colorectal cancer: a bi-directional, two-sample mendelian randomization study.
    BMC Cancer. 2025;25:387.
    PubMed         Abstract available

  19. LENG W, Wen Z, Wang H, Cao P, et al
    Raltitrexed, S-1 and fruquintinib (RSF) in the treatment of refractory metastatic colorectal cancer: study protocol for a multicenter, prospective, single-arm, phase II trial.
    BMC Cancer. 2025;25:376.
    PubMed         Abstract available

  20. LI H, Sun W, Fu S, Wang J, et al
    Prognostic value of the preoperative prognostic nutritional and systemic immunoinflammatory indexes in patients with colorectal cancer.
    BMC Cancer. 2025;25:403.
    PubMed         Abstract available

  21. CHEN C, Fu Q, Wang L, Tanaka S, et al
    Establishment of a novel mouse model of colorectal cancer by orthotopic transplantation.
    BMC Cancer. 2025;25:405.
    PubMed         Abstract available

  22. ALMILAJI O, Sharples L, Aggarwal A, Cromwell D, et al
    Value of hospital administrative data linked to national cancer registry records to identify metastatic disease at time of primary diagnosis in colorectal cancer patients: a study using national data in England.
    BMC Cancer. 2025;25:407.
    PubMed         Abstract available

  23. POWER S, Wooldrage K, Thomas-Gibson S, Cross AJ, et al
    The impact of patient-reported factors of endoscopic screening experience on attendance at future examinations and distal colorectal cancer incidence.
    BMC Cancer. 2025;25:409.
    PubMed         Abstract available


    BMC Gastroenterol

  24. REZAZADEH M, Kamyabi A, Pisheh RG, Noroozie S, et al
    Diagnostic value of peripheral blood inflammatory indices for clinicopathological profile of colorectal cancer: a retrospective observational study.
    BMC Gastroenterol. 2025;25:127.
    PubMed         Abstract available


    BMJ Oncol

  25. IP S, Harrison H, Usher-Smith JA, Barclay ME, et al
    Genetics, primary care records and lifestyle factors for short-term dynamic risk prediction of colorectal cancer: prospective study of asymptomatic and symptomatic UK Biobank participants.
    BMJ Oncol. 2025;4:e000336.
    PubMed         Abstract available

  26. KARTSONAKI C
    Predicting short-term risk of colorectal cancer using primary care records, genetics and lifestyle factors.
    BMJ Oncol. 2025;4:e000637.
    PubMed        


    Br J Cancer

  27. LEE HJ, Park SW, Lee JH, Chang SY, et al
    Differential cellular origins of the extracellular matrix of tumor and normal tissues according to colorectal cancer subtypes.
    Br J Cancer. 2025 Mar 3. doi: 10.1038/s41416-025-02964.
    PubMed         Abstract available


    Cancer Lett

  28. LOPES AL, Paulino AC, Thaumaturgo MAS, Araujo WM, et al
    Dietary intake of the red meat-derived glycan Neu5Gc fuels colorectal cancer through up-regulation of Wnt signaling pathway.
    Cancer Lett. 2025;616:217598.
    PubMed         Abstract available


    Clin Cancer Res

  29. JAZIEH K, Tsai J, Solomon S, Zhu M, et al
    Identification of Candidate Alterations Mediating KRASG12C Inhibitor Resistance in Advanced Colorectal and Pancreatic Cancers.
    Clin Cancer Res. 2025;31:899-906.
    PubMed         Abstract available


    Curr Treat Options Oncol

  30. JIAO J, Wu Y, Wu S, Jiang J, et al
    Enhancing Colorectal Cancer Treatment Through VEGF/VEGFR Inhibitors and Immunotherapy.
    Curr Treat Options Oncol. 2025 Mar 6. doi: 10.1007/s11864-025-01306.
    PubMed         Abstract available


    Dis Colon Rectum

  31. BAEK SJ, Lim H, Oh S, Lee S, et al
    Development of a Predictive Model for Colorectal Cancer Using Exhaled Volatile Organic Compounds.
    Dis Colon Rectum. 2025 Mar 5. doi: 10.1097/DCR.0000000000003706.
    PubMed         Abstract available


    Eur J Surg Oncol

  32. CARRION-ALVAREZ L, Primavesi F, Soreide K, Sochorova D, et al
    Liver metastases from colorectal cancer: A joint ESSO-EAHPBA-UEMS core curriculum collaboration.
    Eur J Surg Oncol. 2025;51:109728.
    PubMed         Abstract available

  33. TANG J, Liao L, Xiao B, Sui Q, et al
    Efficacy and safety of subtotal pelvic peritonectomy for colorectal cancer patients with peritoneal metastasis confined to the pelvic cavity.
    Eur J Surg Oncol. 2025;51:109703.
    PubMed         Abstract available

  34. TIWARI A, Lee SL, MacCabe T, Woyton M, et al
    Intraoperative electron radiotherapy (IOERT) in colorectal cancer: Updated systematic review of techniques, oncological outcomes and complications.
    Eur J Surg Oncol. 2025;51:109724.
    PubMed         Abstract available

  35. GIRARDI L, Mallick R, Wang TF, Carrier M, et al
    Efficacy and safety of extended duration postoperative thromboprophylaxis with low molecular weight heparin among subgroups of patients undergoing surgical resection of colorectal cancer: A post-hoc analysis of the PERIOP-01 trial.
    Eur J Surg Oncol. 2025;51:109701.
    PubMed         Abstract available

  36. GHABRA S, Chang D, Sugarbaker PH
    Preoperative tumor marker elevations in colorectal cancer patients with peritoneal metastases should be used to help select patients for cytoreductive surgery.
    Eur J Surg Oncol. 2025;51:109720.
    PubMed         Abstract available

  37. BAE SU, Lee JL, Yang CS, Park EJ, et al
    Survival benefit of adjuvant chemotherapy in high-risk patients with colon cancer regardless of microsatellite instability.
    Eur J Surg Oncol. 2025;51:109674.
    PubMed         Abstract available

  38. GROEN LC, Timmers TG, Daams FD, Doodeman HJ, et al
    Fit4Surgery app: Home-based prehabilitation app for older patients undergoing elective colorectal cancer surgery.
    Eur J Surg Oncol. 2025;51:109691.
    PubMed         Abstract available


    Gastroenterology

  39. JACOBSON BC, Anderson JC, Burke CA, Dominitz JA, et al
    Optimizing Bowel Preparation Quality for Colonoscopy: Consensus Recommendations by the US Multi-Society Task Force on Colorectal Cancer.
    Gastroenterology. 2025 Feb 25:S0016-5085(25)00361.
    PubMed         Abstract available

  40. HASSAN IN, Ibrahim M
    Regarding "Stool-Based Testing for Post-Polypectomy Colorectal Cancer Surveillance Safely Reduces Colonoscopies: The MOCCAS Study".
    Gastroenterology. 2025 Feb 26:S0016-5085(25)00418.
    PubMed        

  41. YANG C, Shan D
    Toward Optimizing Familial Colorectal Cancer Surveillance Strategies.
    Gastroenterology. 2025 Feb 28:S0016-5085(25)00463.
    PubMed        


    Gastrointest Endosc

  42. CAMUS M, Karsenti D, Levy J, Moreno M, et al
    Success rate of fiducial marker placement for treatment of esophageal or rectal cancers: a prospective multicenter study (FIDECHO study) (with video).
    Gastrointest Endosc. 2025;101:570-577.
    PubMed         Abstract available

  43. TANAKA K, Yabuuchi Y, Imai K, Hosotani K, et al
    Safety and efficacy of underwater EMR for 10- to 20-mm colorectal serrated lesions (SEA CLEAR study).
    Gastrointest Endosc. 2025;101:632-638.
    PubMed         Abstract available

  44. NAGAI M, Ishibashi F, Okusa K, Mochida K, et al
    Optimal visual gaze pattern of endoscopists for improving adenoma detection during colonoscopy (with video).
    Gastrointest Endosc. 2025;101:639-646.
    PubMed         Abstract available

  45. SINGH S, Mohan BP, Vinayek R, Dutta S, et al
    Underwater versus conventional endoscopic submucosal dissection for colorectal lesions: systematic review and meta-analysis.
    Gastrointest Endosc. 2025;101:551-557.
    PubMed         Abstract available

  46. HUANG J, Chan VCW, Chen M, Liew JJM, et al
    Revisiting the Starting Age of Colorectal Cancer Screening for Average-Risk Asian Population: a cost-effectiveness analysis.
    Gastrointest Endosc. 2025 Feb 28:S0016-5107(25)00141.
    PubMed         Abstract available

  47. HOSSEINI-CARROLL P, Dominitz JA, Jacobson BC, May FP, et al
    American Society for Gastrointestinal Endoscopy Colorectal Cancer Screening Project National Summit.
    Gastrointest Endosc. 2025;101:511-519.
    PubMed        

  48. JACOBSON BC, Anderson JC, Burke CA, Dominitz JA, et al
    Optimizing bowel preparation quality for colonoscopy: consensus recommendations by the US Multi-Society Task Force on Colorectal Cancer.
    Gastrointest Endosc. 2025 Mar 3:S0016-5107(25)00080.
    PubMed         Abstract available


    Gut

  49. TE GROEN M, Wijnands AM, den Broeder N, de Jong DJ, et al
    Surveillance in inflammatory bowel disease: white light endoscopy with segmental re-inspection versus dye-based chromoendoscopy - a multi-arm randomised controlled trial (HELIOS).
    Gut. 2025 Jan 16:gutjnl-2024-333446. doi: 10.1136/gutjnl-2024-333446.
    PubMed         Abstract available


    Hum Pathol

  50. LASOTA J, Kaczorowski M, Chlopek M, Milek-Krupa J, et al
    An immunohistochemical and molecular genetic study of 60 colorectal carcinoma brain metastases in pursuit of predictive biomarkers for cancer therapy.
    Hum Pathol. 2025;155:105717.
    PubMed         Abstract available


    Int J Cancer

  51. PEREMIQUEL-TRILLAS P, Martinez JM, Paytubi S, Frias-Gomez J, et al
    Acceptability and somatic mutations in cervicovaginal self-sampling for early endometrial cancer detection in women with Lynch syndrome.
    Int J Cancer. 2025 Feb 14. doi: 10.1002/ijc.35368.
    PubMed         Abstract available


    Int J Colorectal Dis

  52. MORO-VALDEZATE D, Martin-Arevalo J, Cozar-Lozano C, Garcia-Botello S, et al
    Prognostic value of routine blood biomarkers in 3-year survival of resectable colorectal cancer patients: a prognostic nomogram for clinical practice.
    Int J Colorectal Dis. 2025;40:58.
    PubMed         Abstract available


    J Natl Cancer Inst

  53. LIU Y, Song M, Giovannucci EL, Platz EA, et al
    Pre- and post-diagnostic use of antihypertensive medications and stage I-III colorectal cancer survival: prospective cohort study.
    J Natl Cancer Inst. 2025 Feb 25:djaf046. doi: 10.1093.
    PubMed         Abstract available


    J Pathol

  54. AIJALA VK, Harkonen J, Mantere T, Elomaa H, et al
    Comprehensive characterization of micropapillary colorectal adenocarcinoma.
    J Pathol. 2025;265:408-421.
    PubMed         Abstract available


    PLoS One

  55. TOMIMATSU H, Fujimoto K, Suto T, Matsuo M, et al
    Prognosis of extracolonic findings on clinical computed tomographic colonography: A single-center experience.
    PLoS One. 2025;20:e0315601.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  56. JIN J, Zhang R, Li J, Gao F, et al
    The NAE1-mediated neddylation operates as an essential post-translational modification checkpoint for effector CD8(+) T cells.
    Proc Natl Acad Sci U S A. 2025;122:e2424061122.
    PubMed         Abstract available


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