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  Colorectal Neoplasms

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Articles published in Eur J Cancer

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    June 2020
  1. SAKAI D, Taniguchi H, Sugimoto N, Tamura T, et al
    Randomised phase II study of panitumumab plus irinotecan versus cetuximab plus irinotecan in patients with KRAS wild-type metastatic colorectal cancer refractory to fluoropyrimidine, irinotecan and oxaliplatin (WJOG 6510G).
    Eur J Cancer. 2020;135:11-21.
    PubMed     Abstract available

    May 2020
  2. PASQUALETTI G, Schirripa M, Dochy E, Fassan M, et al
    Thyroid hormones ratio is a major prognostic marker in advanced metastatic colorectal cancer: Results from the phase III randomised CORRECT trial.
    Eur J Cancer. 2020;133:66-73.
    PubMed     Abstract available

    April 2020
  3. BERGER MD, Ning Y, Stintzing S, Heinemann V, et al
    A polymorphism within the R-spondin 2 gene predicts outcome in metastatic colorectal cancer patients treated with FOLFIRI/bevacizumab: data from FIRE-3 and TRIBE trials.
    Eur J Cancer. 2020;131:89-97.
    PubMed     Abstract available

    March 2020
  4. ZLOBEC I, Dawson HE, Blank A, Bokhorst JM, et al
    Are tumour grade and tumour budding equivalent in colorectal cancer? A retrospective analysis of 771 patients.
    Eur J Cancer. 2020;130:139-145.
    PubMed     Abstract available

  5. KLINKHAMMER-SCHALKE M, Steinger B, Koller M, Zeman F, et al
    Diagnosing deficits in quality of life and providing tailored therapeutic options: Results of a randomised trial in 220 patients with colorectal cancer.
    Eur J Cancer. 2020;130:102-113.
    PubMed     Abstract available

  6. COHEN R, Vernerey D, Bellera C, Meurisse A, et al
    Guidelines for time-to-event end-point definitions in adjuvant randomised trials for patients with localised colon cancer: Results of the DATECAN initiative.
    Eur J Cancer. 2020;130:63-71.
    PubMed     Abstract available

  7. KIM JW, Han SW, Cho JY, Chung IJ, et al
    Korean red ginseng for cancer-related fatigue in colorectal cancer patients with chemotherapy: A randomised phase III trial.
    Eur J Cancer. 2020;130:51-62.
    PubMed     Abstract available

    February 2020
  8. LUQUE-FERNANDEZ MA, Goncalves K, Salamanca-Fernandez E, Redondo-Sanchez D, et al
    Multimorbidity and short-term overall mortality among colorectal cancer patients in Spain: A population-based cohort study.
    Eur J Cancer. 2020;129:4-14.
    PubMed     Abstract available

    January 2020
  9. BHARDWAJ M, Weigl K, Tikk K, Holland-Letz T, et al
    Multiplex quantitation of 270 plasma protein markers to identify a signature for early detection of colorectal cancer.
    Eur J Cancer. 2020;127:30-40.
    PubMed     Abstract available

  10. FASTNER G, Sedlmayer F, Widder J, Metz M, et al
    Endocrine therapy with or without whole breast irradiation in low-risk breast cancer patients after breast-conserving surgery: 10-year results of the Austrian Breast and Colorectal Cancer Study Group 8A trial.
    Eur J Cancer. 2020;127:12-20.
    PubMed     Abstract available

  11. GINI A, Jansen EEL, Zielonke N, Meester RGS, et al
    Impact of colorectal cancer screening on cancer-specific mortality in Europe: A systematic review.
    Eur J Cancer. 2020 Jan 10. pii: S0959-8049(19)30870.
    PubMed     Abstract available

    November 2019
  12. SUMMERS MG, Maughan TS, Kaplan R, Law PJ, et al
    Comprehensive analysis of colorectal cancer-risk loci and survival outcome: A prognostic role for CDH1 variants.
    Eur J Cancer. 2019;124:56-63.
    PubMed     Abstract available

  13. DUCREUX M, Petersen LN, Ohler L, Bergamo F, et al
    Safety and effectiveness of regorafenib in patients with metastatic colorectal cancer in routine clinical practice in the prospective, observational CORRELATE study.
    Eur J Cancer. 2019;123:146-154.
    PubMed     Abstract available

    October 2019
  14. SOLDEVILLA B, Carretero-Puche C, Gomez-Lopez G, Al-Shahrour F, et al
    The correlation between immune subtypes and consensus molecular subtypes in colorectal cancer identifies novel tumour microenvironment profiles, with prognostic and therapeutic implications.
    Eur J Cancer. 2019;123:118-129.
    PubMed     Abstract available

    August 2019
  15. MUNEMOTO Y, Nakamura M, Takahashi M, Kotaka M, et al
    SAPPHIRE: a randomised phase II study of planned discontinuation or continuous treatment of oxaliplatin after six cycles of modified FOLFOX6 plus panitumumab in patients with colorectal cancer.
    Eur J Cancer. 2019;119:158-167.
    PubMed     Abstract available

  16. GALLOIS C, Artru P, Lievre A, Auclin E, et al
    Evaluation of two nutritional scores' association with systemic treatment toxicity and survival in metastatic colorectal cancer: an AGEO prospective multicentre study.
    Eur J Cancer. 2019;119:35-43.
    PubMed     Abstract available

    July 2019
  17. LOUPAKIS F, Intini R, Cremolini C, Orlandi A, et al
    A validated prognostic classifier for (V600E)BRAF-mutated metastatic colorectal cancer: the 'BRAF BeCool' study.
    Eur J Cancer. 2019;118:121-130.
    PubMed     Abstract available

  18. MILANO G
    More rationale for optimal sequencing of therapeutic monoclonal antibodies in metastatic colorectal cancer.
    Eur J Cancer. 2019;117:131-132.

    June 2019
  19. BROUWER NPM, Heil TC, Olde Rikkert MGM, Lemmens VEPP, et al
    The gap in postoperative outcome between older and younger patients with stage I-III colorectal cancer has been bridged; results from the Netherlands cancer registry.
    Eur J Cancer. 2019;116:1-9.
    PubMed     Abstract available

    May 2019
  20. VAUGHAN-SHAW PG, Zgaga L, Theodoratou E, Blackmur JP, et al
    Whether vitamin D supplementation protects against colorectal cancer risk remains an open question.
    Eur J Cancer. 2019;115:1-3.

    March 2019
  21. ARGILES G, Andre T, Hollebecque A, Calvo A, et al
    Phase I dose-escalation of trifluridine/tipiracil in combination with oxaliplatin in patients with metastatic colorectal cancer.
    Eur J Cancer. 2019;112:12-19.
    PubMed     Abstract available

  22. PUCCINI A, Loupakis F, Stintzing S, Cao S, et al
    Impact of polymorphisms within genes involved in regulating DNA methylation in patients with metastatic colorectal cancer enrolled in three independent, randomised, open-label clinical trials: a meta-analysis from TRIBE, MAVERICC and FIRE-3.
    Eur J Cancer. 2019;111:138-147.
    PubMed     Abstract available

    February 2019
  23. KOSUMI K, Hamada T, Zhang S, Liu L, et al
    Prognostic association of PTGS2 (COX-2) over-expression according to BRAF mutation status in colorectal cancer: Results from two prospective cohorts and CALGB 89803 (Alliance) trial.
    Eur J Cancer. 2019;111:82-93.
    PubMed     Abstract available

  24. CASCINU S, Poli D, Zaniboni A, Lonardi S, et al
    The prognostic impact of primary tumour location in patients with stage II and stage III colon cancer receiving adjuvant therapy. A GISCAD analysis from three large randomised trials.
    Eur J Cancer. 2019;111:1-7.
    PubMed     Abstract available

  25. ANDERSSON TM, Engholm G, Lund AQ, Lourenco S, et al
    Avoidable cancers in the Nordic countries-the potential impact of increased physical activity on postmenopausal breast, colon and endometrial cancer.
    Eur J Cancer. 2019;110:42-48.
    PubMed     Abstract available

  26. CREMOLINI C, Marmorino F, Bergamo F, Aprile G, et al
    Phase II randomised study of maintenance treatment with bevacizumab or bevacizumab plus metronomic chemotherapy after first-line induction with FOLFOXIRI plus Bevacizumab for metastatic colorectal cancer patients: the MOMA trial.
    Eur J Cancer. 2019;109:175-182.
    PubMed     Abstract available

    January 2019
  27. MODEST DP, Pant S, Sartore-Bianchi A
    Treatment sequencing in metastatic colorectal cancer.
    Eur J Cancer. 2019;109:70-83.
    PubMed     Abstract available

    December 2018
  28. SCHWARTZ S, Szeto C, Tian Y, Cecchi F, et al
    Refining the selection of patients with metastatic colorectal cancer for treatment with temozolomide using proteomic analysis of O6-methylguanine-DNA-methyltransferase.
    Eur J Cancer. 2018;107:164-174.
    PubMed     Abstract available

  29. SUENAGA M, Stintzing S, Cao S, Zhang W, et al
    Role of CCL5 and CCR5 gene polymorphisms in epidermal growth factor receptor signalling blockade in metastatic colorectal cancer: analysis of the FIRE-3 trial.
    Eur J Cancer. 2018;107:100-114.
    PubMed     Abstract available

    November 2018
  30. HOLCH JW, Ricard I, Stintzing S, Fischer von Weikersthal L, et al
    Relevance of baseline carcinoembryonic antigen for first-line treatment against metastatic colorectal cancer with FOLFIRI plus cetuximab or bevacizumab (FIRE-3 trial).
    Eur J Cancer. 2018;106:115-125.
    PubMed     Abstract available

  31. BARANISKIN A, Buchberger B, Pox C, Graeven U, et al
    Efficacy of bevacizumab in first-line treatment of metastatic colorectal cancer: A systematic review and meta-analysis.
    Eur J Cancer. 2018;106:37-44.
    PubMed     Abstract available

  32. IMANISHI M, Yamamoto Y, Hamano Y, Yamada T, et al
    Efficacy of adjuvant chemotherapy after resection of pulmonary metastasis from colorectal cancer: a propensity score-matched analysis.
    Eur J Cancer. 2018;106:69-77.
    PubMed     Abstract available

    October 2018
    Synergistic activity of dasatinib in combination with beta-catenin blockade in colorectal cancer cells.
    Eur J Cancer. 2018 Oct 12. pii: S0959-8049(18)31366.

    September 2018
  34. SALEM ME, Yin J, Weinberg BA, Renfro LA, et al
    Clinicopathological differences and survival outcomes with first-line therapy in patients with left-sided colon cancer and rectal cancer: Pooled analysis of 2879 patients from AGITG (MAX), COIN, FOCUS2, OPUS, CRYSTAL and COIN-B trials in the ARCAD dat
    Eur J Cancer. 2018;103:205-213.
    PubMed     Abstract available

  35. LORD AC, D'Souza N, Pucher PH, Moran BJ, et al
    Author response to comment on 'significance of extranodal tumour deposits in colorectal cancer: A systematic review and meta-analysis'.
    Eur J Cancer. 2018 Sep 25. pii: S0959-8049(18)31336.

  36. GOOTJES EC, Bakkerus L, Ten Tije AJ, Witteveen PO, et al
    The value of tumour debulking for patients with extensive multi-organ metastatic colorectal cancer.
    Eur J Cancer. 2018;103:160-164.
    PubMed     Abstract available

  37. HAMADA T, Liu L, Nowak JA, Mima K, et al
    Vitamin D status after colorectal cancer diagnosis and patient survival according to immune response to tumour.
    Eur J Cancer. 2018;103:98-107.
    PubMed     Abstract available

  38. HIRST Y, Stoffel S, Baio G, McGregor L, et al
    Uptake of the English Bowel (Colorectal) Cancer Screening Programme: an update 5 years after the full roll-out.
    Eur J Cancer. 2018 Sep 6. pii: S0959-8049(18)31120.
    PubMed     Abstract available

    August 2018
  39. MADI A, Fisher D, Maughan TS, Colley JP, et al
    Pharmacogenetic analyses of 2183 patients with advanced colorectal cancer; potential role for common dihydropyrimidine dehydrogenase variants in toxicity to chemotherapy.
    Eur J Cancer. 2018;102:31-39.
    PubMed     Abstract available

  40. TEJPAR S, Yan P, Piessevaux H, Dietrich D, et al
    Clinical and pharmacogenetic determinants of 5-fluorouracyl/leucovorin/irinotecan toxicity: Results of the PETACC-3 trial.
    Eur J Cancer. 2018;99:66-77.
    PubMed     Abstract available

    July 2018
  41. ARANDA E, Garcia Alfonso P, Benavides M, Sanchez Ruiz A, et al
    First-line mFOLFOX plus cetuximab followed by mFOLFOX plus cetuximab or single-agent cetuximab as maintenance therapy in patients with metastatic colorectal cancer: Phase II randomised MACRO2 TTD study.
    Eur J Cancer. 2018 Jul 24. pii: S0959-8049(18)30938.
    PubMed     Abstract available

  42. HEGEWISCH-BECKER S, Nopel-Dunnebacke S, Hinke A, Graeven U, et al
    Impact of primary tumour location and RAS/BRAF mutational status in metastatic colorectal cancer treated with first-line regimens containing oxaliplatin and bevacizumab: Prognostic factors from the AIO KRK0207 first-line and maintenance therapy trial.
    Eur J Cancer. 2018;101:105-113.
    PubMed     Abstract available

  43. GELLI M, Huguenin JFL, de Baere T, Benhaim L, et al
    Peritoneal and extraperitoneal relapse after previous curative treatment of peritoneal metastases from colorectal cancer: What survival can we expect?
    Eur J Cancer. 2018;100:94-103.
    PubMed     Abstract available

    June 2018
  44. GOEY KKH, Sorbye H, Glimelius B, Adams RA, et al
    Consensus statement on essential patient characteristics in systemic treatment trials for metastatic colorectal cancer: Supported by the ARCAD Group.
    Eur J Cancer. 2018;100:35-45.
    PubMed     Abstract available

  45. STOCKER G, Hacker UT, Fiteni F, John Mahachie J, et al
    Clinical consequences of chemotherapy dose reduction in obese patients with stage III colon cancer: A retrospective analysis from the PETACC 3 study.
    Eur J Cancer. 2018;99:49-57.
    PubMed     Abstract available

    May 2018
  46. APARICIO T, Ducreux M, Faroux R, Barbier E, et al
    Overweight is associated to a better prognosis in metastatic colorectal cancer: A pooled analysis of FFCD trials.
    Eur J Cancer. 2018;98:1-9.
    PubMed     Abstract available

  47. APARICIO T, Bouche O, Francois E, Retornaz F, et al
    Geriatric analysis from PRODIGE 20 randomized phase II trial evaluating bevacizumab + chemotherapy versus chemotherapy alone in older patients with untreated metastatic colorectal cancer.
    Eur J Cancer. 2018;97:16-24.
    PubMed     Abstract available

  48. AUCLIN E, Andre T, Taieb J, Benetkiewicz M, et al
    Low-level postoperative carcinoembryonic antigen improves survival outcomes stratification in patients with stage II colon cancer treated with standard adjuvant treatments.
    Eur J Cancer. 2018 May 3. pii: S0959-8049(18)30782.

  49. GOEY KKH, Mahmoud R, Sorbye H, Glimelius B, et al
    Reporting of patient characteristics and stratification factors in phase 3 trials investigating first-line systemic treatment of metastatic colorectal cancer: A systematic review.
    Eur J Cancer. 2018;96:115-124.
    PubMed     Abstract available

    April 2018
  50. MARGALIT O, Mamtani R, Yang YX, Reiss KA, et al
    A new look at the International Duration Evaluation of Adjuvant therapy (IDEA) classification-Defining novel predictive and prognostic markers in stage III colon cancer.
    Eur J Cancer. 2018;96:105-110.
    PubMed     Abstract available

  51. MATSUDA C, Ishiguro M, Teramukai S, Kajiwara Y, et al
    A randomised-controlled trial of 1-year adjuvant chemotherapy with oral tegafur-uracil versus surgery alone in stage II colon cancer: SACURA trial.
    Eur J Cancer. 2018;96:54-63.
    PubMed     Abstract available

    March 2018
  52. TACHON G, Frouin E, Karayan-Tapon L, Auriault ML, et al
    Heterogeneity of mismatch repair defect in colorectal cancer and its implications in clinical practice.
    Eur J Cancer. 2018 Mar 5. pii: S0959-8049(18)30121.

  53. MARGALIT O, Mamtani R, Yang YX, Reiss KA, et al
    Assessing the prognostic value of carcinoembryonic antigen levels in stage I and II colon cancer.
    Eur J Cancer. 2018;94:1-5.
    PubMed     Abstract available

  54. OGURA A, Akiyoshi T, Yamamoto N, Kawachi H, et al
    Pattern of programmed cell death-ligand 1 expression and CD8-positive T-cell infiltration before and after chemoradiotherapy in rectal cancer.
    Eur J Cancer. 2018;91:11-20.
    PubMed     Abstract available

    February 2018
  55. YOSHINO T, Hsu Y, Nasroulah F
    Response to Letter to the Editor, 'Pharmacokinetics partly explains the relationship between CEA level and survival of colorectal cancer patients treated with ramucirumab,' by Ibrahim et al.
    Eur J Cancer. 2018 Feb 9. pii: S0959-8049(18)30084.

  56. ZOU D, Lou J, Ke J, Mei S, et al
    Integrative expression quantitative trait locus-based analysis of colorectal cancer identified a functional polymorphism regulating SLC22A5 expression.
    Eur J Cancer. 2018;93:1-9.
    PubMed     Abstract available

    January 2018
  57. VAN ROOIJEN KL, Shi Q, Goey KKH, Meyers J, et al
    Prognostic value of primary tumour resection in synchronous metastatic colorectal cancer: Individual patient data analysis of first-line randomised trials from the ARCAD database.
    Eur J Cancer. 2018;91:99-106.
    PubMed     Abstract available

  58. IBRAHIM S, Raoul W, Lecomte T, Paintaud G, et al
    Pharmacokinetics partly explains the relationship between carcinoembryonic antigen level and survival of colorectal cancer patients treated with ramucirumab.
    Eur J Cancer. 2018 Jan 9. pii: S0959-8049(17)31461.

  59. VON MOOS R, Koeberle D, Schacher S, Hayoz S, et al
    Neoadjuvant radiotherapy combined with capecitabine and sorafenib in patients with advanced KRAS-mutated rectal cancer: A phase I/II trial (SAKK 41/08).
    Eur J Cancer. 2018;89:82-89.
    PubMed     Abstract available

  60. SWETS M, Kuppen PJK, Blok EJ, Gelderblom H, et al
    Are pathological high-risk features in locally advanced rectal cancer a useful selection tool for adjuvant chemotherapy?
    Eur J Cancer. 2018;89:1-8.
    PubMed     Abstract available

    December 2017
  61. VAN CUTSEM E, Mayer RJ, Laurent S, Winkler R, et al
    The subgroups of the phase III RECOURSE trial of trifluridine/tipiracil (TAS-102) versus placebo with best supportive care in patients with metastatic colorectal cancer.
    Eur J Cancer. 2017;90:63-72.
    PubMed     Abstract available

    November 2017
  62. MODEST DP, Denecke T, Pratschke J, Ricard I, et al
    Surgical treatment options following chemotherapy plus cetuximab or bevacizumab in metastatic colorectal cancer-central evaluation of FIRE-3.
    Eur J Cancer. 2017;88:77-86.
    PubMed     Abstract available

  63. COHEN R, Buhard O, Cervera P, Hain E, et al
    Clinical and molecular characterisation of hereditary and sporadic metastatic colorectal cancers harbouring microsatellite instability/DNA mismatch repair deficiency.
    Eur J Cancer. 2017;86:266-274.
    PubMed     Abstract available

    October 2017
  64. SUENAGA M, Schirripa M, Cao S, Zhang W, et al
    Potential role of polymorphisms in the transporter genes ENT1 and MATE1/OCT2 in predicting TAS-102 efficacy and toxicity in patients with refractory metastatic colorectal cancer.
    Eur J Cancer. 2017;86:197-206.
    PubMed     Abstract available

  65. KEIKES L, Koopman M, Tanis PJ, Lemmens VEPP, et al
    Evaluating the scientific basis of quality indicators in colorectal cancer care: A systematic review.
    Eur J Cancer. 2017;86:166-177.
    PubMed     Abstract available

  66. PREVOSTEL C, Blache P
    The dose-dependent effect of SOX9 and its incidence in colorectal cancer.
    Eur J Cancer. 2017;86:150-157.
    PubMed     Abstract available

  67. MALKA D, Rotolo F, Boige V
    First-line treatment in metastatic colorectal cancer: Important or crucial?
    Eur J Cancer. 2017;84:363-366.

    September 2017
  68. TURATI F, Bravi F, Di Maso M, Bosetti C, et al
    Adherence to the World Cancer Research Fund/American Institute for Cancer Research recommendations and colorectal cancer risk.
    Eur J Cancer. 2017;85:86-94.
    PubMed     Abstract available

    August 2017
  69. KWAKMAN JJM, Baars A, van Zweeden AA, de Mol P, et al
    Case series of patients treated with the oral fluoropyrimidine S-1 after capecitabine-induced coronary artery vasospasm.
    Eur J Cancer. 2017;81:130-134.

    January 2017
  70. CHAN AK, Siriwardena AK
    Management of synchronous liver metastases and the recommendations of the second St. Gallen European Organisation for Research and Treatment of Cancer consensus conference on the management of rectal cancer.
    Eur J Cancer. 2017;71:51-52.

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