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  Colorectal Neoplasms

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Articles published in Gut

Retrieve available abstracts of 46 articles:
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Single Articles


    January 2026
  1. LADABAUM U, Font Marimon R, Castells Olivera X, Balaguer F, et al
    Effect of long-term adherence on faecal immunochemical test positivity rate, positive predictive value and detection rate in organised population-based colorectal cancer screening.
    Gut. 2026 Jan 30:gutjnl-2025-336994. doi: 10.1136/gutjnl-2025-336994.
    PubMed     Abstract available


  2. VIJAY-KUMAR M, Yeoh BS, Gewirtz AT
    Hydroxylation matters! Microbial bile acid metabolism and colorectal cancer.
    Gut. 2026 Jan 28:gutjnl-2025-337583. doi: 10.1136/gutjnl-2025-337583.
    PubMed    


    December 2025

  3. Correction: RNA-binding protein RALY reprogrammes mitochondrial metabolism via mediating miRNA processing in colorectal cancer.
    Gut. 2025 Dec 25:gutjnl-2020-320652corr1. doi: 10.1136/gutjnl-2020-320652.
    PubMed    


  4. TAN H, Huang L, Wang J, Huang H, et al
    Parasutterella excrementihominis exacerbates experimental colitis and colitis-associated colorectal cancer via pathogenic NETosis activation.
    Gut. 2025 Dec 25:gutjnl-2025-335887. doi: 10.1136/gutjnl-2025-335887.
    PubMed     Abstract available


  5. DU M, Wang X, Hang D, Wang F, et al
    Metabolomic pattern of ultraprocessed food intake and its association with colorectal cancer risk.
    Gut. 2025 Dec 24:gutjnl-2025-335618. doi: 10.1136/gutjnl-2025-335618.
    PubMed     Abstract available


  6. OSSWALD A, Wortmann E, Wylensek D, Kuhls S, et al
    Secondary bile acid production by gut bacteria promotes Western diet-associated colorectal cancer.
    Gut. 2025 Dec 18:gutjnl-2024-332243. doi: 10.1136/gutjnl-2024-332243.
    PubMed     Abstract available


  7. CHEN Y, Padilla Aponte J, Wang K, Du M, et al
    Comparative risk of high-risk neoplasia after polypectomy among individuals aged below 50 years versus 50 years and older.
    Gut. 2025;75:72-80.
    PubMed     Abstract available


    November 2025
  8. GRANCHER A, Denis B, Plaine J, Vidal-Sengchanh S, et al
    Does a long time to colonoscopy after a positive faecal immunochemical test result have a deleterious impact on colorectal cancer outcomes? A nationwide cohort study.
    Gut. 2025 Nov 27:gutjnl-2025-336036. doi: 10.1136/gutjnl-2025-336036.
    PubMed     Abstract available


  9. VAN DER SCHEE L, Albers SC, Didden P, Lacle MM, et al
    Results of endoscopic intermuscular dissection for deep submucosal invasive rectal cancer: a three-year follow-up study.
    Gut. 2025;74:1995-2003.
    PubMed     Abstract available


    October 2025
  10. STEUP C, Kennel K, Neurath MF, Fichtner-Feigl S, et al
    Current and emerging concepts for systemic treatment of metastatic colorectal cancer.
    Gut. 2025 Oct 5:gutjnl-2025-335412. doi: 10.1136/gutjnl-2025-335412.
    PubMed     Abstract available


    September 2025
  11. CUI Y, Liu H, Zhang L, Zhang H, et al
    Fructose drives colorectal cancer progression by regulating crosstalk between cancer-associated fibroblasts and tumour cells.
    Gut. 2025 Sep 11:gutjnl-2025-335014. doi: 10.1136/gutjnl-2025-335014.
    PubMed     Abstract available


  12. RUTTER MD, Ranjan R, Westwood C, Barbour J, et al
    BSG/ACPGBI guidance on the management of colorectal polyps in patients with limited life expectancy.
    Gut. 2025;74:1551-1560.
    PubMed     Abstract available


  13. BAATRUP G, Bjorsum-Meyer T, Kaalby L, Schelde-Olesen B, et al
    Choice of colon capsule or colonoscopy versus default colonoscopy in FIT positive patients in the Danish screening programme: a parallel group randomised controlled trial.
    Gut. 2025;74:1616-1623.
    PubMed     Abstract available


    August 2025
  14. FIORI ME
    Gut feeling: extracellular vesicles dictate liver's susceptibility to colorectal cancer metastasis.
    Gut. 2025 Aug 25:gutjnl-2025-336108. doi: 10.1136/gutjnl-2025-336108.
    PubMed    


    July 2025
  15. WANG S, Ye G, Xu X, Lin Y, et al
    Pericyte drives the formation of circulating tumour cell-neutrophil clusters to promote colorectal cancer metastasis.
    Gut. 2025 Jul 23:gutjnl-2024-334618. doi: 10.1136/gutjnl-2024-334618.
    PubMed     Abstract available


    June 2025
  16. FRAZZONI L, Antonelli G, Pilonis ND, Wisse PHA, et al
    Adenoma detection and subsequent colorectal cancer risk: is the race really over?
    Gut. 2025 Jun 27:gutjnl-2025-335225. doi: 10.1136/gutjnl-2025-335225.
    PubMed    


  17. CAO J, Qin S, Li B, Zhang Z, et al
    Extracellular vesicle-induced lipid dysregulation drives liver premetastatic niche formation in colorectal cancer.
    Gut. 2025 Jun 25:gutjnl-2025-334851. doi: 10.1136/gutjnl-2025-334851.
    PubMed     Abstract available


  18. DREWS J, Zachaus M, Kleemann T, Schirra J, et al
    Multicentre randomised controlled trial of a self-assembling haemostatic gel to prevent delayed bleeding following endoscopic mucosal resection (PURPLE Trial).
    Gut. 2025;74:1103-1111.
    PubMed     Abstract available


  19. SOUNDARARAJAN R, Halade G, Yeatman TJ
    Response to the letter to the editor 'revisiting lipid dysregulation in colorectal cancer: critical appraisal of pro-inflammatory bias and therapeutic implications'.
    Gut. 2025 Jun 4:gutjnl-2025-335452. doi: 10.1136/gutjnl-2025-335452.
    PubMed    


  20. ZHANG Y, Song W, Zhou L, Wei S, et al
    Bacteria-metabolite butyrate boosts anti-PD1 efficacy in colorectal cancer patient-derived organoids through activating autologous tumour-infiltrating GNLY (+)CD8(+) T cells.
    Gut. 2025 Jun 1:gutjnl-2025-335306. doi: 10.1136/gutjnl-2025-335306.
    PubMed    


    April 2025
  21. GAUCI JL, Mandarino FV, Kerrison C, Whitfield AM, et al
    Margin thermal ablation eliminates size as a risk factor for recurrence after piecemeal endoscopic mucosal resection of large non-pedunculated colorectal polyps.
    Gut. 2025;74:752-760.
    PubMed     Abstract available


  22. ROBBINS EC, Wooldrage K, Rutter MD, Veitch AM, et al
    Colorectal cancer incidence after the first surveillance colonoscopy and the need for ongoing surveillance: a retrospective, cohort analysis.
    Gut. 2025 Apr 5:gutjnl-2024-334242. doi: 10.1136/gutjnl-2024-334242.
    PubMed     Abstract available


  23. ZHU X
    Revisiting lipid dysregulation in colorectal cancer: critical appraisal of pro-inflammatory bias and therapeutic implications.
    Gut. 2025 Apr 2:gutjnl-2025-335153. doi: 10.1136/gutjnl-2025-335153.
    PubMed    


    March 2025
  24. DIGBY J, Nobes J, Strachan JA, McCann R, et al
    Combining faecal haemoglobin, iron deficiency anaemia status and age can improve colorectal cancer risk prediction in patients attending primary care with bowel symptoms: a retrospective observational study.
    Gut. 2025 Mar 26:gutjnl-2024-334248. doi: 10.1136/gutjnl-2024-334248.
    PubMed     Abstract available


    February 2025
  25. HU M, Xu Y, Wang Y, Huang Z, et al
    Gut microbial-derived N-acetylmuramic acid alleviates colorectal cancer via the AKT1 pathway.
    Gut. 2025 Feb 27:gutjnl-2024-332891. doi: 10.1136/gutjnl-2024-332891.
    PubMed     Abstract available


    January 2025
  26. AL BAKIR I, Curtius K, Cresswell GD, Grant HE, et al
    Low-coverage whole genome sequencing of low-grade dysplasia strongly predicts advanced neoplasia risk in ulcerative colitis.
    Gut. 2025 Jan 29:gutjnl-2024-333353. doi: 10.1136/gutjnl-2024-333353.
    PubMed     Abstract available


  27. NAN K, Zhong Z, Yue Y, Shen Y, et al
    Fasting-mimicking diet-enriched Bifidobacterium pseudolongum suppresses colorectal cancer by inducing memory CD8(+) T cells.
    Gut. 2025 Jan 27:gutjnl-2024-333020. doi: 10.1136/gutjnl-2024-333020.
    PubMed     Abstract available


  28. ZHOU Q, Lei L, Cheng J, Chen J, et al
    Microbiota-induced S100A11-RAGE axis underlies immune evasion in right-sided colon adenomas and is a therapeutic target to boost anti-PD1 efficacy.
    Gut. 2025;74:214-228.
    PubMed     Abstract available


  29. TE GROEN M, Wijnands AM, den Broeder N, de Jong DJ, et al
    Surveillance in inflammatory bowel disease: white light endoscopy with segmental re-inspection versus dye-based chromoendoscopy - a multi-arm randomised controlled trial (HELIOS).
    Gut. 2025 Jan 16:gutjnl-2024-333446. doi: 10.1136/gutjnl-2024-333446.
    PubMed     Abstract available


    December 2024
  30. WANG S, Peng F, Dang M, Jiao H, et al
    Early detection of colorectal cancer using aberrant circulating cell-free mitochondrial DNA fragmentomics.
    Gut. 2024 Dec 18:gutjnl-2024-333533. doi: 10.1136/gutjnl-2024-333533.
    PubMed     Abstract available


  31. SOUNDARARAJAN R, Maurin MM, Rodriguez-Silva J, Upadhyay G, et al
    Integration of lipidomics with targeted, single cell, and spatial transcriptomics defines an unresolved pro-inflammatory state in colon cancer.
    Gut. 2024 Dec 10:gutjnl-2024-332535. doi: 10.1136/gutjnl-2024-332535.
    PubMed     Abstract available


    November 2024
  32. RAJASEKARAN V, Harris BT, Osborn RT, Smillie C, et al
    Genetic variation at 11q23.1 confers colorectal cancer risk by dysregulation of colonic tuft cell transcriptional activator POU2AF2.
    Gut. 2024 Nov 28:gutjnl-2024-332121. doi: 10.1136/gutjnl-2024-332121.
    PubMed     Abstract available


  33. SCHWARZMUELLER LJ, Adam RS, Moreno LF, Nijman LE, et al
    Identifying colorectal cancer-specific vulnerabilities in the Wnt-driven long non-coding transcriptome.
    Gut. 2024 Nov 19:gutjnl-2024-332752. doi: 10.1136/gutjnl-2024-332752.
    PubMed     Abstract available


  34. SINONQUEL P, Eelbode T, Pech O, De Wulf D, et al
    Clinical consequences of computer-aided colorectal polyp detection.
    Gut. 2024;73:1974-1983.
    PubMed     Abstract available


  35. QU R, Zhang Z, Fu W
    Potential microbial effects on microsatellite instability possibly drive divergence in colorectal cancer immunotherapy responses among different anatomical subsites.
    Gut. 2024 Nov 5:gutjnl-2024-334008. doi: 10.1136/gutjnl-2024-334008.
    PubMed    


    September 2024
  36. POLYCHRONIDIS G, He MM, Vithayathil M, Knudsen MD, et al
    Risk of colorectal neoplasia after removal of conventional adenomas and serrated polyps: a comprehensive evaluation of risk factors and surveillance use.
    Gut. 2024;73:1675-1683.
    PubMed     Abstract available


  37. MANDARINO FV, Medas R, Gauci JL, Kerrison C, et al
    Endoscopic mucosal resection for large non-pedunculated colorectal polyps: staying on track with a safe, effective and cost-efficient technique.
    Gut. 2024;73:e13.
    PubMed    


    August 2024
  38. SU ACY, Ding X, Lau HCH, Kang X, et al
    Lactococcus lactis HkyuLL 10 suppresses colorectal tumourigenesis and restores gut microbiota through its generated alpha-mannosidase.
    Gut. 2024;73:1478-1488.
    PubMed     Abstract available


  39. CHEN J, Hai Y, Li Y, Wang C, et al
    Colonic multiple polypoidal protrusions: not familial adenomatous polyposis.
    Gut. 2024;73:1430-1463.
    PubMed    


  40. DJORDJEVIC J, Cisneros Romero NS, Cascione L, Mele V, et al
    Direct toll-like receptor triggering in colorectal cancer-associated stromal cells elicits immunostimulatory properties leading to enhanced immune cell recruitment.
    Gut. 2024 Aug 8:gutjnl-2023-331759. doi: 10.1136/gutjnl-2023-331759.
    PubMed    


    July 2024
  41. MAO X, Cheung KS, Tan JT, Mak LY, et al
    Optimal glycaemic control and the reduced risk of colorectal adenoma and cancer in patients with diabetes: a population-based cohort study.
    Gut. 2024;73:1313-1320.
    PubMed     Abstract available


    June 2024
  42. IACUCCI M, Santacroce G, Majumder S, Morael J, et al
    Opening the doors of precision medicine: novel tools to assess intestinal barrier in inflammatory bowel disease and colitis-associated neoplasia.
    Gut. 2024 Jun 8:gutjnl-2023-331579. doi: 10.1136/gutjnl-2023-331579.
    PubMed     Abstract available


    May 2024
  43. OULADAN S, Orouji E
    Beyond traditional subtyping: a multilayered genomic perspective on colorectal cancer.
    Gut. 2024 May 15:gutjnl-2024-332325. doi: 10.1136/gutjnl-2024-332325.
    PubMed    


    April 2024
  44. MEULEN LWT, Bogie RMM, Siersema PD, Winkens B, et al
    Standardised training for endoscopic mucosal resection of large non-pedunculated colorectal polyps to reduce recurrence (*STAR-LNPCP study): a multicentre cluster randomised trial.
    Gut. 2024;73:741-750.
    PubMed     Abstract available


    March 2024
  45. CHEN S, Xin J, Gu D, Li H, et al
    Smoking-related Lactobacillus and immune cell infiltration in colorectal cancer: evidence from a population-based study.
    Gut. 2024 Mar 18:gutjnl-2023-331865. doi: 10.1136/gutjnl-2023-331865.
    PubMed    


    February 2024
  46. ABDELRAHIM M, Siggens K, Iwadate Y, Maeda N, et al
    New AI model for neoplasia detection and characterisation in inflammatory bowel disease.
    Gut. 2024 Feb 23:gutjnl-2023-330718. doi: 10.1136/gutjnl-2023-330718.
    PubMed    


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