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Colorectal Neoplasms

Free Subscription Articles published in Gut Retrieve available abstracts of 58 articles: HTML format

Single Articles

June 2026
1. HAN X, Xu HM, Liu ZC, Zhang L, et al
   Helicobacter pylori infection, treatment and colorectal cancer risk by genetic predisposition: evidence from two randomised trials.
   Gut. 2026 Jun 30:gutjnl-2026-338156. doi: 10.1136/gutjnl-2026-338156.
   PubMed     Abstract available
   
   
   
2. 
   Correction: Blockade of interleukin 10 potentiates antitumour immune function in human colorectal cancer liver metastases.
   Gut. 2026 Jun 26:gutjnl-2021-325808corr1. doi: 10.1136/gutjnl-2021-325808.
   PubMed    
   
   
   
3. WANG J, Zhou M, Tan B, Shi H, et al
   SPP1(+) macrophages facilitate the differentiation and maturation of regulatory T cells in tumour-draining lymph nodes of colorectal cancer.
   Gut. 2026 Jun 12:gutjnl-2025-337038. doi: 10.1136/gutjnl-2025-337038.
   PubMed     Abstract available
   
   
   
4. PALLES C, Freeman-Mills L, Arbe-Barnes E, Feeley N, et al
   Comparison between germline and somatic loss-of-function RNF43 mutations reveals different genotype-phenotype associations and provides insights into the genetic mechanisms of colorectal tumourigenesis.
   Gut. 2026;75:1353-1366.
   PubMed     Abstract available
   
   
   
5. HOU Y, Wu H, Zhang Z, Wang J, et al
   Bacteroides intestinalis mediates the sensitivity to irinotecan toxicity via tryptophan catabolites.
   Gut. 2026;75:1322-1337.
   PubMed     Abstract available
   
   
   May 2026
6. CAI R, Zhan W, Lyu X, Yang X, et al
   PTEN deficiency impairs MHC-I-mediated tumour immunity via NRF2-dependent autophagy in microsatellite stable colorectal cancer.
   Gut. 2026 May 22:gutjnl-2026-338195. doi: 10.1136/gutjnl-2026-338195.
   PubMed     Abstract available
   
   
   
7. YANG H, Dungan M, Madhu B, Beyries K, et al
   MAIT cell enrichment in Lynch syndrome is associated with immune surveillance and colorectal cancer risk.
   Gut. 2026 May 19:gutjnl-2025-337343. doi: 10.1136/gutjnl-2025-337343.
   PubMed     Abstract available
   
   
   April 2026
8. LI X, Xie M, Kang JX, Chen Y, et al
   Bifidobacterium catenulatum boosts anti-PD-1 efficacy in microsatellite stable colorectal cancer via activating CD8(+) T cells.
   Gut. 2026 Apr 9:gutjnl-2025-336025. doi: 10.1136/gutjnl-2025-336025.
   PubMed     Abstract available
   
   
   
9. LIU C, Gong J, Luo Z, Lai P, et al
   Gut microbe alleviates stress-related cancer metastasis by oleic acid degradation.
   Gut. 2026;75:968-983.
   PubMed     Abstract available
   
   
   March 2026
10. AWONIYI M, El Hag M, Hernandez J, Yang Q, et al
    Dysbiotic microbiota trigger colitis-associated colorectal cancer and imprint a distinctive bile acid profile in a PSC-IBD model.
    Gut. 2026 Mar 23:gutjnl-2025-336675. doi: 10.1136/gutjnl-2025-336675.
    PubMed     Abstract available
    
    
    
11. JANSSEN KP, Basic M, Bolsega S, Metwaly A, et al
    Extrinsic lipids are absorbed and accumulate in colorectal cancer.
    Gut. 2026 Mar 19:gutjnl-2025-336377. doi: 10.1136/gutjnl-2025-336377.
    PubMed     Abstract available
    
    
    January 2026
12. LADABAUM U, Font Marimon R, Castells Olivera X, Balaguer F, et al
    Effect of long-term adherence on faecal immunochemical test positivity rate, positive predictive value and detection rate in organised population-based colorectal cancer screening.
    Gut. 2026 Jan 30:gutjnl-2025-336994. doi: 10.1136/gutjnl-2025-336994.
    PubMed     Abstract available
    
    
    
13. VIJAY-KUMAR M, Yeoh BS, Gewirtz AT
    Hydroxylation matters! Microbial bile acid metabolism and colorectal cancer.
    Gut. 2026 Jan 28:gutjnl-2025-337583. doi: 10.1136/gutjnl-2025-337583.
    PubMed    
    
    
    
14. WU CT, Targher G, Byrne CD, Younossi ZM, et al
    Colorectal cancer in metabolic dysfunction-associated steatotic liver disease: an international Delphi consensus statement.
    Gut. 2026 Jan 21:gutjnl-2025-337374. doi: 10.1136/gutjnl-2025-337374.
    PubMed     Abstract available
    
    
    December 2025
15. 
    Correction: RNA-binding protein RALY reprogrammes mitochondrial metabolism via mediating miRNA processing in colorectal cancer.
    Gut. 2025 Dec 25:gutjnl-2020-320652corr1. doi: 10.1136/gutjnl-2020-320652.
    PubMed    
    
    
    
16. TAN H, Huang L, Wang J, Huang H, et al
    Parasutterella excrementihominis exacerbates experimental colitis and colitis-associated colorectal cancer via pathogenic NETosis activation.
    Gut. 2025 Dec 25:gutjnl-2025-335887. doi: 10.1136/gutjnl-2025-335887.
    PubMed     Abstract available
    
    
    
17. DU M, Wang X, Hang D, Wang F, et al
    Metabolomic pattern of ultraprocessed food intake and its association with colorectal cancer risk.
    Gut. 2025 Dec 24:gutjnl-2025-335618. doi: 10.1136/gutjnl-2025-335618.
    PubMed     Abstract available
    
    
    
18. OSSWALD A, Wortmann E, Wylensek D, Kuhls S, et al
    Secondary bile acid production by gut bacteria promotes Western diet-associated colorectal cancer.
    Gut. 2025 Dec 18:gutjnl-2024-332243. doi: 10.1136/gutjnl-2024-332243.
    PubMed     Abstract available
    
    
    
19. CHEN Y, Padilla Aponte J, Wang K, Du M, et al
    Comparative risk of high-risk neoplasia after polypectomy among individuals aged below 50 years versus 50 years and older.
    Gut. 2025;75:72-80.
    PubMed     Abstract available
    
    
    November 2025
20. GRANCHER A, Denis B, Plaine J, Vidal-Sengchanh S, et al
    Does a long time to colonoscopy after a positive faecal immunochemical test result have a deleterious impact on colorectal cancer outcomes? A nationwide cohort study.
    Gut. 2025 Nov 27:gutjnl-2025-336036. doi: 10.1136/gutjnl-2025-336036.
    PubMed     Abstract available
    
    
    
21. VAN DER SCHEE L, Albers SC, Didden P, Lacle MM, et al
    Results of endoscopic intermuscular dissection for deep submucosal invasive rectal cancer: a three-year follow-up study.
    Gut. 2025;74:1995-2003.
    PubMed     Abstract available
    
    
    October 2025
22. STEUP C, Kennel K, Neurath MF, Fichtner-Feigl S, et al
    Current and emerging concepts for systemic treatment of metastatic colorectal cancer.
    Gut. 2025 Oct 5:gutjnl-2025-335412. doi: 10.1136/gutjnl-2025-335412.
    PubMed     Abstract available
    
    
    September 2025
23. CUI Y, Liu H, Zhang L, Zhang H, et al
    Fructose drives colorectal cancer progression by regulating crosstalk between cancer-associated fibroblasts and tumour cells.
    Gut. 2025 Sep 11:gutjnl-2025-335014. doi: 10.1136/gutjnl-2025-335014.
    PubMed     Abstract available
    
    
    
24. RUTTER MD, Ranjan R, Westwood C, Barbour J, et al
    BSG/ACPGBI guidance on the management of colorectal polyps in patients with limited life expectancy.
    Gut. 2025;74:1551-1560.
    PubMed     Abstract available
    
    
    
25. BAATRUP G, Bjorsum-Meyer T, Kaalby L, Schelde-Olesen B, et al
    Choice of colon capsule or colonoscopy versus default colonoscopy in FIT positive patients in the Danish screening programme: a parallel group randomised controlled trial.
    Gut. 2025;74:1616-1623.
    PubMed     Abstract available
    
    
    August 2025
26. FIORI ME
    Gut feeling: extracellular vesicles dictate liver's susceptibility to colorectal cancer metastasis.
    Gut. 2025 Aug 25:gutjnl-2025-336108. doi: 10.1136/gutjnl-2025-336108.
    PubMed    
    
    
    July 2025
27. WANG S, Ye G, Xu X, Lin Y, et al
    Pericyte drives the formation of circulating tumour cell-neutrophil clusters to promote colorectal cancer metastasis.
    Gut. 2025 Jul 23:gutjnl-2024-334618. doi: 10.1136/gutjnl-2024-334618.
    PubMed     Abstract available
    
    
    June 2025
28. FRAZZONI L, Antonelli G, Pilonis ND, Wisse PHA, et al
    Adenoma detection and subsequent colorectal cancer risk: is the race really over?
    Gut. 2025 Jun 27:gutjnl-2025-335225. doi: 10.1136/gutjnl-2025-335225.
    PubMed    
    
    
    
29. CAO J, Qin S, Li B, Zhang Z, et al
    Extracellular vesicle-induced lipid dysregulation drives liver premetastatic niche formation in colorectal cancer.
    Gut. 2025 Jun 25:gutjnl-2025-334851. doi: 10.1136/gutjnl-2025-334851.
    PubMed     Abstract available
    
    
    
30. DREWS J, Zachaus M, Kleemann T, Schirra J, et al
    Multicentre randomised controlled trial of a self-assembling haemostatic gel to prevent delayed bleeding following endoscopic mucosal resection (PURPLE Trial).
    Gut. 2025;74:1103-1111.
    PubMed     Abstract available
    
    
    
31. SOUNDARARAJAN R, Halade G, Yeatman TJ
    Response to the letter to the editor 'revisiting lipid dysregulation in colorectal cancer: critical appraisal of pro-inflammatory bias and therapeutic implications'.
    Gut. 2025 Jun 4:gutjnl-2025-335452. doi: 10.1136/gutjnl-2025-335452.
    PubMed    
    
    
    
32. ZHANG Y, Song W, Zhou L, Wei S, et al
    Bacteria-metabolite butyrate boosts anti-PD1 efficacy in colorectal cancer patient-derived organoids through activating autologous tumour-infiltrating GNLY (+)CD8(+) T cells.
    Gut. 2025 Jun 1:gutjnl-2025-335306. doi: 10.1136/gutjnl-2025-335306.
    PubMed    
    
    
    April 2025
33. GAUCI JL, Mandarino FV, Kerrison C, Whitfield AM, et al
    Margin thermal ablation eliminates size as a risk factor for recurrence after piecemeal endoscopic mucosal resection of large non-pedunculated colorectal polyps.
    Gut. 2025;74:752-760.
    PubMed     Abstract available
    
    
    
34. ROBBINS EC, Wooldrage K, Rutter MD, Veitch AM, et al
    Colorectal cancer incidence after the first surveillance colonoscopy and the need for ongoing surveillance: a retrospective, cohort analysis.
    Gut. 2025 Apr 5:gutjnl-2024-334242. doi: 10.1136/gutjnl-2024-334242.
    PubMed     Abstract available
    
    
    
35. ZHU X
    Revisiting lipid dysregulation in colorectal cancer: critical appraisal of pro-inflammatory bias and therapeutic implications.
    Gut. 2025 Apr 2:gutjnl-2025-335153. doi: 10.1136/gutjnl-2025-335153.
    PubMed    
    
    
    March 2025
36. DIGBY J, Nobes J, Strachan JA, McCann R, et al
    Combining faecal haemoglobin, iron deficiency anaemia status and age can improve colorectal cancer risk prediction in patients attending primary care with bowel symptoms: a retrospective observational study.
    Gut. 2025 Mar 26:gutjnl-2024-334248. doi: 10.1136/gutjnl-2024-334248.
    PubMed     Abstract available
    
    
    February 2025
37. HU M, Xu Y, Wang Y, Huang Z, et al
    Gut microbial-derived N-acetylmuramic acid alleviates colorectal cancer via the AKT1 pathway.
    Gut. 2025 Feb 27:gutjnl-2024-332891. doi: 10.1136/gutjnl-2024-332891.
    PubMed     Abstract available
    
    
    January 2025
38. AL BAKIR I, Curtius K, Cresswell GD, Grant HE, et al
    Low-coverage whole genome sequencing of low-grade dysplasia strongly predicts advanced neoplasia risk in ulcerative colitis.
    Gut. 2025 Jan 29:gutjnl-2024-333353. doi: 10.1136/gutjnl-2024-333353.
    PubMed     Abstract available
    
    
    
39. NAN K, Zhong Z, Yue Y, Shen Y, et al
    Fasting-mimicking diet-enriched Bifidobacterium pseudolongum suppresses colorectal cancer by inducing memory CD8(+) T cells.
    Gut. 2025 Jan 27:gutjnl-2024-333020. doi: 10.1136/gutjnl-2024-333020.
    PubMed     Abstract available
    
    
    
40. ZHOU Q, Lei L, Cheng J, Chen J, et al
    Microbiota-induced S100A11-RAGE axis underlies immune evasion in right-sided colon adenomas and is a therapeutic target to boost anti-PD1 efficacy.
    Gut. 2025;74:214-228.
    PubMed     Abstract available
    
    
    
41. TE GROEN M, Wijnands AM, den Broeder N, de Jong DJ, et al
    Surveillance in inflammatory bowel disease: white light endoscopy with segmental re-inspection versus dye-based chromoendoscopy - a multi-arm randomised controlled trial (HELIOS).
    Gut. 2025 Jan 16:gutjnl-2024-333446. doi: 10.1136/gutjnl-2024-333446.
    PubMed     Abstract available
    
    
    December 2024
42. WANG S, Peng F, Dang M, Jiao H, et al
    Early detection of colorectal cancer using aberrant circulating cell-free mitochondrial DNA fragmentomics.
    Gut. 2024 Dec 18:gutjnl-2024-333533. doi: 10.1136/gutjnl-2024-333533.
    PubMed     Abstract available
    
    
    
43. SOUNDARARAJAN R, Maurin MM, Rodriguez-Silva J, Upadhyay G, et al
    Integration of lipidomics with targeted, single cell, and spatial transcriptomics defines an unresolved pro-inflammatory state in colon cancer.
    Gut. 2024 Dec 10:gutjnl-2024-332535. doi: 10.1136/gutjnl-2024-332535.
    PubMed     Abstract available
    
    
    November 2024
44. RAJASEKARAN V, Harris BT, Osborn RT, Smillie C, et al
    Genetic variation at 11q23.1 confers colorectal cancer risk by dysregulation of colonic tuft cell transcriptional activator POU2AF2.
    Gut. 2024 Nov 28:gutjnl-2024-332121. doi: 10.1136/gutjnl-2024-332121.
    PubMed     Abstract available
    
    
    
45. SCHWARZMUELLER LJ, Adam RS, Moreno LF, Nijman LE, et al
    Identifying colorectal cancer-specific vulnerabilities in the Wnt-driven long non-coding transcriptome.
    Gut. 2024 Nov 19:gutjnl-2024-332752. doi: 10.1136/gutjnl-2024-332752.
    PubMed     Abstract available
    
    
    
46. SINONQUEL P, Eelbode T, Pech O, De Wulf D, et al
    Clinical consequences of computer-aided colorectal polyp detection.
    Gut. 2024;73:1974-1983.
    PubMed     Abstract available
    
    
    
47. QU R, Zhang Z, Fu W
    Potential microbial effects on microsatellite instability possibly drive divergence in colorectal cancer immunotherapy responses among different anatomical subsites.
    Gut. 2024 Nov 5:gutjnl-2024-334008. doi: 10.1136/gutjnl-2024-334008.
    PubMed    
    
    
    September 2024
48. POLYCHRONIDIS G, He MM, Vithayathil M, Knudsen MD, et al
    Risk of colorectal neoplasia after removal of conventional adenomas and serrated polyps: a comprehensive evaluation of risk factors and surveillance use.
    Gut. 2024;73:1675-1683.
    PubMed     Abstract available
    
    
    
49. MANDARINO FV, Medas R, Gauci JL, Kerrison C, et al
    Endoscopic mucosal resection for large non-pedunculated colorectal polyps: staying on track with a safe, effective and cost-efficient technique.
    Gut. 2024;73:e13.
    PubMed    
    
    
    August 2024
50. SU ACY, Ding X, Lau HCH, Kang X, et al
    Lactococcus lactis HkyuLL 10 suppresses colorectal tumourigenesis and restores gut microbiota through its generated alpha-mannosidase.
    Gut. 2024;73:1478-1488.
    PubMed     Abstract available
    
    
    
51. CHEN J, Hai Y, Li Y, Wang C, et al
    Colonic multiple polypoidal protrusions: not familial adenomatous polyposis.
    Gut. 2024;73:1430-1463.
    PubMed    
    
    
    
52. DJORDJEVIC J, Cisneros Romero NS, Cascione L, Mele V, et al
    Direct toll-like receptor triggering in colorectal cancer-associated stromal cells elicits immunostimulatory properties leading to enhanced immune cell recruitment.
    Gut. 2024 Aug 8:gutjnl-2023-331759. doi: 10.1136/gutjnl-2023-331759.
    PubMed    
    
    
    July 2024
53. MAO X, Cheung KS, Tan JT, Mak LY, et al
    Optimal glycaemic control and the reduced risk of colorectal adenoma and cancer in patients with diabetes: a population-based cohort study.
    Gut. 2024;73:1313-1320.
    PubMed     Abstract available
    
    
    June 2024
54. IACUCCI M, Santacroce G, Majumder S, Morael J, et al
    Opening the doors of precision medicine: novel tools to assess intestinal barrier in inflammatory bowel disease and colitis-associated neoplasia.
    Gut. 2024 Jun 8:gutjnl-2023-331579. doi: 10.1136/gutjnl-2023-331579.
    PubMed     Abstract available
    
    
    May 2024
55. OULADAN S, Orouji E
    Beyond traditional subtyping: a multilayered genomic perspective on colorectal cancer.
    Gut. 2024 May 15:gutjnl-2024-332325. doi: 10.1136/gutjnl-2024-332325.
    PubMed    
    
    
    April 2024
56. MEULEN LWT, Bogie RMM, Siersema PD, Winkens B, et al
    Standardised training for endoscopic mucosal resection of large non-pedunculated colorectal polyps to reduce recurrence (*STAR-LNPCP study): a multicentre cluster randomised trial.
    Gut. 2024;73:741-750.
    PubMed     Abstract available
    
    
    March 2024
57. CHEN S, Xin J, Gu D, Li H, et al
    Smoking-related Lactobacillus and immune cell infiltration in colorectal cancer: evidence from a population-based study.
    Gut. 2024 Mar 18:gutjnl-2023-331865. doi: 10.1136/gutjnl-2023-331865.
    PubMed    
    
    
    February 2024
58. ABDELRAHIM M, Siggens K, Iwadate Y, Maeda N, et al
    New AI model for neoplasia detection and characterisation in inflammatory bowel disease.
    Gut. 2024 Feb 23:gutjnl-2023-330718. doi: 10.1136/gutjnl-2023-330718.
    PubMed    
    
    

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