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Articles published in Oncogene

Retrieve available abstracts of 97 articles:
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Single Articles


    July 2022
  1. ZHAO L, Zhang X, Zhou Y, Fu K, et al
    Parvimonas micra promotes colorectal tumorigenesis and is associated with prognosis of colorectal cancer patients.
    Oncogene. 2022 Jul 27. pii: 10.1038/s41388-022-02395.
    PubMed     Abstract available


  2. YOU A, Tian W, Yuan H, Gu L, et al
    TTC22 promotes m6A-mediated WTAP expression and colon cancer metastasis in an RPL4 binding-dependent pattern.
    Oncogene. 2022 Jul 7. pii: 10.1038/s41388-022-02402.
    PubMed     Abstract available


    June 2022
  3. PUCCINI A, Poorman K, Catalano F, Seeber A, et al
    Molecular profiling of signet-ring-cell carcinoma (SRCC) from the stomach and colon reveals potential new therapeutic targets.
    Oncogene. 2022;41:3455-3460.
    PubMed     Abstract available


    May 2022
  4. CHEN Y, Zhou S, Wan K, Yu L, et al
    RIOK1 mediates p53 degradation and radioresistance in colorectal cancer through phosphorylation of G3BP2.
    Oncogene. 2022 May 19. pii: 10.1038/s41388-022-02352.
    PubMed     Abstract available


  5. YANG L, WenTao T, ZhiYuan Z, Qi L, et al
    Cullin-9/p53 mediates HNRNPC degradation to inhibit erastin-induced ferroptosis and is blocked by MDM2 inhibition in colorectal cancer.
    Oncogene. 2022 May 3. pii: 10.1038/s41388-022-02284.
    PubMed     Abstract available


    April 2022
  6. CHEN Z, Zhang X, Xing Z, Lv S, et al
    OLFM4 deficiency delays the progression of colitis to colorectal cancer by abrogating PMN-MDSCs recruitment.
    Oncogene. 2022 Apr 29. pii: 10.1038/s41388-022-02324.
    PubMed     Abstract available


  7. GUO P, Chen Q, Peng K, Xie J, et al
    Nuclear receptor coactivator SRC-1 promotes colorectal cancer progression through enhancing GLI2-mediated Hedgehog signaling.
    Oncogene. 2022 Apr 13. pii: 10.1038/s41388-022-02308.
    PubMed     Abstract available


  8. SHI C, Tao S, Ren G, Yang EJ, et al
    Aurora kinase A inhibition induces synthetic lethality in SMAD4-deficient colorectal cancer cells via spindle assembly checkpoint activation.
    Oncogene. 2022 Apr 7. pii: 10.1038/s41388-022-02293.
    PubMed     Abstract available


  9. CUI YM, Jiao HL, Ye YP, Chen CM, et al
    Retraction Note to: FOXC2 promotes colorectal cancer metastasis by directly targeting MET.
    Oncogene. 2022 Apr 1. pii: 10.1038/s41388-022-02287.
    PubMed    


  10. BAKER K, O'Donnell C, Bendix M, Keogh S, et al
    IL-36 signalling enhances a pro-tumorigenic phenotype in colon cancer cells with cancer cell growth restricted by administration of the IL-36R antagonist.
    Oncogene. 2022 Apr 1. pii: 10.1038/s41388-022-02281.
    PubMed     Abstract available


  11. MAGRIN L, Fanale D, Brando C, Corsini LR, et al
    MUTYH-associated tumor syndrome: The other face of MAP.
    Oncogene. 2022;41:2531-2539.
    PubMed     Abstract available


    March 2022
  12. RAO VS, Gu Q, Tzschentke S, Lin K, et al
    Extravesicular TIMP-1 is a non-invasive independent prognostic marker and potential therapeutic target in colorectal liver metastases.
    Oncogene. 2022;41:1809-1820.
    PubMed     Abstract available


  13. FLUM M, Dicks S, Teng YH, Schrempp M, et al
    Canonical TGFbeta signaling induces collective invasion in colorectal carcinogenesis through a Snail1- and Zeb1-independent partial EMT.
    Oncogene. 2022;41:1492-1506.
    PubMed     Abstract available


    February 2022
  14. QIAO G, Kone LB, Phillips EH, Lee SS, et al
    LIGHT enhanced bispecific antibody armed T-cells to treat immunotherapy resistant colon cancer.
    Oncogene. 2022 Feb 17. pii: 10.1038/s41388-022-02209.
    PubMed     Abstract available


  15. PARK YL, Kim HP, Ock CY, Min DW, et al
    EMT-mediated regulation of CXCL1/5 for resistance to anti-EGFR therapy in colorectal cancer.
    Oncogene. 2022 Feb 16. pii: 10.1038/s41388-021-01920.
    PubMed     Abstract available


  16. WU H, Ding X, Hu X, Zhao Q, et al
    LINC01021 maintains tumorigenicity by enhancing N6-methyladenosine reader IMP2 dependent stabilization of MSX1 and JARID2: implication in colorectal cancer.
    Oncogene. 2022 Feb 16. pii: 10.1038/s41388-022-02189.
    PubMed     Abstract available


  17. LI B, Kang H, Xiao Y, Du Y, et al
    LncRNA GAL promotes colorectal cancer liver metastasis through stabilizing GLUT1.
    Oncogene. 2022 Feb 11. pii: 10.1038/s41388-022-02230.
    PubMed     Abstract available


  18. GUERRA E, Relli V, Ceci M, Tripaldi R, et al
    Trop-2, Na(+)/K(+) ATPase, CD9, PKCalpha, cofilin assemble a membrane signaling super-complex that drives colorectal cancer growth and invasion.
    Oncogene. 2022 Feb 7. pii: 10.1038/s41388-022-02220.
    PubMed     Abstract available


    January 2022
  19. SALIBA J, Coutaud B, Makhani K, Epstein Roth N, et al
    Loss of NFE2L3 protects against inflammation-induced colorectal cancer through modulation of the tumor microenvironment.
    Oncogene. 2022 Jan 28. pii: 10.1038/s41388-022-02192.
    PubMed     Abstract available


  20. HE XS, Ye WL, Zhang YJ, Yang XQ, et al
    Oncogenic potential of BEST4 in colorectal cancer via activation of PI3K/Akt signaling.
    Oncogene. 2022 Jan 21. pii: 10.1038/s41388-021-02160.
    PubMed     Abstract available


  21. CHEN Q, Zhuang S, Hong Y, Yang L, et al
    Demethylase JMJD2D induces PD-L1 expression to promote colorectal cancer immune escape by enhancing IFNGR1-STAT3-IRF1 signaling.
    Oncogene. 2022 Jan 14. pii: 10.1038/s41388-021-02173.
    PubMed     Abstract available


  22. LIN J, Xia L, Oyang L, Liang J, et al
    The POU2F1-ALDOA axis promotes the proliferation and chemoresistance of colon cancer cells by enhancing glycolysis and the pentose phosphate pathway activity.
    Oncogene. 2022 Jan 8. pii: 10.1038/s41388-021-02148.
    PubMed     Abstract available


  23. ZHENG D, Cao M, Zuo S, Xia X, et al
    Correction: RANBP1 promotes colorectal cancer progression by regulating pre-miRNA nuclear export via a positive feedback loop with YAP.
    Oncogene. 2022 Jan 4. pii: 10.1038/s41388-021-02152.
    PubMed    


    December 2021
  24. FREY P, Devisme A, Rose K, Schrempp M, et al
    SMAD4 mutations do not preclude epithelial-mesenchymal transition in colorectal cancer.
    Oncogene. 2021 Dec 3. pii: 10.1038/s41388-021-02128.
    PubMed     Abstract available


  25. LI Z, He Y, Li Y, Li J, et al
    NeuroD1 promotes tumor cell proliferation and tumorigenesis by directly activating the pentose phosphate pathway in colorectal carcinoma.
    Oncogene. 2021;40:6736-6747.
    PubMed     Abstract available


  26. CAO CH, Ling H, Han K, Lu XP, et al
    PPIP5K2 promotes colorectal carcinoma pathogenesis through facilitating DNA homologous recombination repair.
    Oncogene. 2021;40:6680-6691.
    PubMed     Abstract available


  27. WANG S, Wong CC, Zhang Y, Huang J, et al
    ZNF545 loss promotes ribosome biogenesis and protein translation to initiate colorectal tumorigenesis in mice.
    Oncogene. 2021;40:6590-6600.
    PubMed     Abstract available


    November 2021
  28. VERY N, Hardiville S, Decourcelle A, Thevenet J, et al
    Thymidylate synthase O-GlcNAcylation: a molecular mechanism of 5-FU sensitization in colorectal cancer.
    Oncogene. 2021 Nov 29. pii: 10.1038/s41388-021-02121.
    PubMed     Abstract available


  29. MA L, Lin Y, Sun SW, Xu J, et al
    KIAA1429 is a potential prognostic marker in colorectal cancer by promoting the proliferation via downregulating WEE1 expression in an m6A-independent manner.
    Oncogene. 2021 Nov 24. pii: 10.1038/s41388-021-02066.
    PubMed     Abstract available


  30. HAN F, Zhang L, Liao S, Zhang Y, et al
    The interaction between S100A2 and KPNA2 mediates NFYA nuclear import and is a novel therapeutic target for colorectal cancer metastasis.
    Oncogene. 2021 Nov 20. pii: 10.1038/s41388-021-02116.
    PubMed     Abstract available


  31. HE F, Song Z, Chen H, Chen Z, et al
    Correction: Long noncoding RNA PVT1-214 promotes proliferation and invasion of colorectal cancer by stabilizing Lin28 and interacting with miR-128.
    Oncogene. 2021 Nov 9. pii: 10.1038/s41388-021-02093.
    PubMed    


  32. ARAI H, Elliott A, Millstein J, Xiu J, et al
    Molecular characteristics and clinical outcomes of patients with Neurofibromin 1-altered metastatic colorectal cancer.
    Oncogene. 2021 Nov 2. pii: 10.1038/s41388-021-02074.
    PubMed     Abstract available


  33. POLOSUKHINA D, Singh K, Asim M, Barry DP, et al
    CCL11 exacerbates colitis and inflammation-associated colon tumorigenesis.
    Oncogene. 2021;40:6540-6546.
    PubMed     Abstract available


  34. XU H, Wong CC, Li W, Zhou Y, et al
    RING-finger protein 6 promotes colorectal tumorigenesis by transcriptionally activating SF3B2.
    Oncogene. 2021;40:6513-6526.
    PubMed     Abstract available


    October 2021
  35. YU C, Luo D, Yu J, Zhang M, et al
    Genome-wide CRISPR-cas9 knockout screening identifies GRB7 as a driver for MEK inhibitor resistance in KRAS mutant colon cancer.
    Oncogene. 2021 Oct 30. pii: 10.1038/s41388-021-02077.
    PubMed     Abstract available


  36. YU S, Zang W, Qiu Y, Liao L, et al
    Deubiquitinase OTUB2 exacerbates the progression of colorectal cancer by promoting PKM2 activity and glycolysis.
    Oncogene. 2021 Oct 20. pii: 10.1038/s41388-021-02071.
    PubMed     Abstract available


  37. ZHANG J, Zhai J, Wong CC, Chen H, et al
    A novel amplification gene PCI domain containing 2 (PCID2) promotes colorectal cancer through directly degrading a tumor suppressor promyelocytic leukemia (PML).
    Oncogene. 2021 Oct 8. pii: 10.1038/s41388-021-01941.
    PubMed     Abstract available


  38. GAO S, Soares F, Wang S, Wong CC, et al
    CRISPR screens identify cholesterol biosynthesis as a therapeutic target on stemness and drug resistance of colon cancer.
    Oncogene. 2021 Oct 7. pii: 10.1038/s41388-021-01882.
    PubMed     Abstract available


  39. ZHENG D, Cao M, Zuo S, Xia X, et al
    RANBP1 promotes colorectal cancer progression by regulating pre-miRNA nuclear export via a positive feedback loop with YAP.
    Oncogene. 2021 Oct 6. pii: 10.1038/s41388-021-02036.
    PubMed     Abstract available


  40. TONG J, Tan X, Risnik D, Gao M, et al
    BET protein degradation triggers DR5-mediated immunogenic cell death to suppress colorectal cancer and potentiate immune checkpoint blockade.
    Oncogene. 2021 Oct 6. pii: 10.1038/s41388-021-02041.
    PubMed     Abstract available


  41. HUA Q, Zhang B, Xu G, Wang L, et al
    CEMIP, a novel adaptor protein of OGT, promotes colorectal cancer metastasis through glutamine metabolic reprogramming via reciprocal regulation of beta-catenin.
    Oncogene. 2021 Oct 4. pii: 10.1038/s41388-021-02023.
    PubMed     Abstract available


  42. TONG K, Kothari OA, Haro KS, Panda A, et al
    SMAD4 is critical in suppression of BRAF-V600E serrated tumorigenesis.
    Oncogene. 2021;40:6034-6048.
    PubMed     Abstract available


  43. CHEN L, Jin XH, Luo J, Duan JL, et al
    ITLN1 inhibits tumor neovascularization and myeloid derived suppressor cells accumulation in colorectal carcinoma.
    Oncogene. 2021;40:5925-5937.
    PubMed     Abstract available


    September 2021
  44. ZHANG W, Pan R, Lu M, Zhang Q, et al
    Epigenetic induction of lipocalin 2 expression drives acquired resistance to 5-fluorouracil in colorectal cancer through integrin beta3/SRC pathway.
    Oncogene. 2021 Sep 29. pii: 10.1038/s41388-021-02029.
    PubMed     Abstract available


    August 2021
  45. YANG G, Huang L, Jia H, Aikemu B, et al
    NDRG1 enhances the sensitivity of cetuximab by modulating EGFR trafficking in colorectal cancer.
    Oncogene. 2021 Aug 12. pii: 10.1038/s41388-021-01962.
    PubMed     Abstract available


  46. CEN B, Wei J, Wang D, Xiong Y, et al
    Mutant APC promotes tumor immune evasion via PD-L1 in colorectal cancer.
    Oncogene. 2021 Aug 12. pii: 10.1038/s41388-021-01972.
    PubMed     Abstract available


  47. GUO W, Zhang C, Feng P, Li M, et al
    M6A methylation of DEGS2, a key ceramide-synthesizing enzyme, is involved in colorectal cancer progression through ceramide synthesis.
    Oncogene. 2021 Aug 6. pii: 10.1038/s41388-021-01987.
    PubMed     Abstract available


  48. QIAO S, Lu W, Glorieux C, Li J, et al
    Wild-type IDH2 protects nuclear DNA from oxidative damage and is a potential therapeutic target in colorectal cancer.
    Oncogene. 2021 Aug 4. pii: 10.1038/s41388-021-01968.
    PubMed     Abstract available


  49. ZHANG J, Jiang X, Yin J, Dou S, et al
    RNF141 interacts with KRAS to promote colorectal cancer progression.
    Oncogene. 2021 Aug 3. pii: 10.1038/s41388-021-01877.
    PubMed     Abstract available


  50. LIEBS S, Eder T, Klauschen F, Schutte M, et al
    Applicability of liquid biopsies to represent the mutational profile of tumor tissue from different cancer entities.
    Oncogene. 2021;40:5204-5212.
    PubMed     Abstract available


    July 2021
  51. CABOT D, Brun S, Paco N, Ginesta MM, et al
    KRAS phosphorylation regulates cell polarization and tumorigenic properties in colorectal cancer.
    Oncogene. 2021 Jul 31. pii: 10.1038/s41388-021-01967.
    PubMed     Abstract available


  52. FAN X, Wang Y, Jiang T, Liu T, et al
    B-Myb accelerates colorectal cancer progression through reciprocal feed-forward transactivation of E2F2.
    Oncogene. 2021 Jul 27. pii: 10.1038/s41388-021-01961.
    PubMed     Abstract available


  53. KOBELT D, Perez-Hernandez D, Fleuter C, Dahlmann M, et al
    The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis.
    Oncogene. 2021 Jul 10. pii: 10.1038/s41388-021-01917.
    PubMed     Abstract available


  54. RUAN DY, Li T, Wang YN, Meng Q, et al
    FTO downregulation mediated by hypoxia facilitates colorectal cancer metastasis.
    Oncogene. 2021 Jul 3. pii: 10.1038/s41388-021-01916.
    PubMed     Abstract available


    June 2021
  55. SUN L, Patai AV, Hogenson TL, Fernandez-Zapico ME, et al
    Irreversible JNK blockade overcomes PD-L1-mediated resistance to chemotherapy in colorectal cancer.
    Oncogene. 2021 Jun 30. pii: 10.1038/s41388-021-01910.
    PubMed     Abstract available


  56. ZHAO S, Guan B, Mi Y, Shi D, et al
    LncRNA MIR17HG promotes colorectal cancer liver metastasis by mediating a glycolysis-associated positive feedback circuit.
    Oncogene. 2021 Jun 18. pii: 10.1038/s41388-021-01859.
    PubMed     Abstract available


  57. WANG H, Wang X, Zhang H, Deng T, et al
    The HSF1/miR-135b-5p axis induces protective autophagy to promote oxaliplatin resistance through the MUL1/ULK1 pathway in colorectal cancer.
    Oncogene. 2021 Jun 17. pii: 10.1038/s41388-021-01898.
    PubMed     Abstract available


  58. MCANDREWS KM, Vazquez-Arreguin K, Kwak C, Sugimoto H, et al
    alphaSMA(+) fibroblasts suppress Lgr5(+) cancer stem cells and restrain colorectal cancer progression.
    Oncogene. 2021 Jun 9. pii: 10.1038/s41388-021-01866.
    PubMed     Abstract available


  59. MALKOMES P, Lunger I, Oppermann E, Abou-El-Ardat K, et al
    Transglutaminase 2 promotes tumorigenicity of colon cancer cells by inactivation of the tumor suppressor p53.
    Oncogene. 2021 Jun 8. pii: 10.1038/s41388-021-01847.
    PubMed     Abstract available


    May 2021
  60. YOU J, Li J, Ke C, Xiao Y, et al
    Oncogenic long intervening noncoding RNA Linc00284 promotes c-Met expression by sponging miR-27a in colorectal cancer.
    Oncogene. 2021 May 28. pii: 10.1038/s41388-021-01839.
    PubMed     Abstract available


  61. CHEN J, Na R, Xiao C, Wang X, et al
    The loss of SHMT2 mediates 5-fluorouracil chemoresistance in colorectal cancer by upregulating autophagy.
    Oncogene. 2021 May 14. pii: 10.1038/s41388-021-01815.
    PubMed     Abstract available


  62. ZHANG XL, Hu LP, Yang Q, Qin WT, et al
    CTHRC1 promotes liver metastasis by reshaping infiltrated macrophages through physical interactions with TGF-beta receptors in colorectal cancer.
    Oncogene. 2021 May 13. pii: 10.1038/s41388-021-01827.
    PubMed     Abstract available


  63. ZENG K, Chen X, Hu X, Liu X, et al
    Correction: LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation.
    Oncogene. 2021 May 6. pii: 10.1038/s41388-021-01795.
    PubMed    


  64. JUNG HR, Oh Y, Na D, Min S, et al
    CRISPR screens identify a novel combination treatment targeting BCL-XL and WNT signaling for KRAS/BRAF-mutated colorectal cancers.
    Oncogene. 2021;40:3287-3302.
    PubMed     Abstract available


    April 2021
  65. LIU J, Huang Z, Chen HN, Qin S, et al
    ZNF37A promotes tumor metastasis through transcriptional control of THSD4/TGF-beta axis in colorectal cancer.
    Oncogene. 2021 Apr 19. pii: 10.1038/s41388-021-01713.
    PubMed     Abstract available


  66. XIAO Q, Gan Y, Li Y, Fan L, et al
    MEF2A transcriptionally upregulates the expression of ZEB2 and CTNNB1 in colorectal cancer to promote tumor progression.
    Oncogene. 2021 Apr 16. pii: 10.1038/s41388-021-01774.
    PubMed     Abstract available


  67. SONG D, Lan J, Chen Y, Liu A, et al
    NSD2 promotes tumor angiogenesis through methylating and activating STAT3 protein.
    Oncogene. 2021;40:2952-2967.
    PubMed     Abstract available


  68. MANTILLA-ROJAS C, Yu M, Rinella ES, Lynch RM, et al
    A molecular subtype of colorectal cancers initiates independently of epidermal growth factor receptor and has an accelerated growth rate mediated by IL10-dependent anergy.
    Oncogene. 2021;40:3047-3059.
    PubMed     Abstract available


    March 2021
  69. CHUEH AC, Advani G, Foroutan M, Smith J, et al
    CSK-homologous kinase (CHK/MATK) is a potential colorectal cancer tumour suppressor gene epigenetically silenced by promoter methylation.
    Oncogene. 2021 Mar 25. pii: 10.1038/s41388-021-01755.
    PubMed     Abstract available


  70. WESTENDORP F, Karpus ON, Koelink PJ, Vermeulen JLM, et al
    Epithelium-derived Indian Hedgehog restricts stromal expression of ErbB family members that drive colonic tumor cell proliferation.
    Oncogene. 2021;40:1628-1643.
    PubMed     Abstract available


  71. GOLLAVILLI PN, Parma B, Siddiqui A, Yang H, et al
    The role of miR-200b/c in balancing EMT and proliferation revealed by an activity reporter.
    Oncogene. 2021;40:2309-2322.
    PubMed     Abstract available


  72. FLETCHER R, Tong J, Risnik D, Leibowitz BJ, et al
    Non-steroidal anti-inflammatory drugs induce immunogenic cell death in suppressing colorectal tumorigenesis.
    Oncogene. 2021;40:2035-2050.
    PubMed     Abstract available


    February 2021
  73. CUI K, Yao S, Zhang H, Zhou M, et al
    Identification of an immune overdrive high-risk subpopulation with aberrant expression of FOXP3 and CTLA4 in colorectal cancer.
    Oncogene. 2021 Feb 24. pii: 10.1038/s41388-021-01677.
    PubMed     Abstract available


  74. PENG K, Zhuo M, Li M, Chen Q, et al
    Correction to: Histone demethylase JMJD2D activates HIF1 signaling pathway via multiple mechanisms to promote colorectal cancer glycolysis and progression.
    Oncogene. 2021 Feb 22. pii: 10.1038/s41388-021-01678.
    PubMed    


  75. XU H, Liu L, Li W, Zou D, et al
    Correction: Transcription factors in colorectal cancer: molecular mechanism and therapeutic implications.
    Oncogene. 2021 Feb 9. pii: 10.1038/s41388-021-01651.
    PubMed    


    January 2021
  76. YIN XK, Wang YL, Wang F, Feng WX, et al
    PRMT1 enhances oncogenic arginine methylation of NONO in colorectal cancer.
    Oncogene. 2021 Jan 8. pii: 10.1038/s41388-020-01617.
    PubMed     Abstract available


  77. LI H, Zhao L, Lau YS, Zhang C, et al
    Genome-wide CRISPR screen identifies LGALS2 as an oxidative stress-responsive gene with an inhibitory function on colon tumor growth.
    Oncogene. 2021;40:177-188.
    PubMed     Abstract available


  78. GIRONDEL C, Levesque K, Langlois MJ, Pasquin S, et al
    Loss of interleukin-17 receptor D promotes chronic inflammation-associated tumorigenesis.
    Oncogene. 2021;40:452-464.
    PubMed     Abstract available


  79. SCHMIDT AK, Pudelko K, Boekenkamp JE, Berger K, et al
    The p53/p73 - p21(CIP1) tumor suppressor axis guards against chromosomal instability by restraining CDK1 in human cancer cells.
    Oncogene. 2021;40:436-451.
    PubMed     Abstract available


  80. BALA P, Singh AK, Kavadipula P, Kotapalli V, et al
    Exome sequencing identifies ARID2 as a novel tumor suppressor in early-onset sporadic rectal cancer.
    Oncogene. 2021;40:863-874.
    PubMed     Abstract available


    December 2020
  81. XU H, Liu L, Li W, Zou D, et al
    Transcription factors in colorectal cancer: molecular mechanism and therapeutic implications.
    Oncogene. 2020 Dec 15. pii: 10.1038/s41388-020-01587.
    PubMed     Abstract available


  82. BERGIN CJ, Zouggar A, Haebe JR, Masibag AN, et al
    G9a controls pluripotent-like identity and tumor-initiating function in human colorectal cancer.
    Oncogene. 2020 Dec 15. pii: 10.1038/s41388-020-01591.
    PubMed     Abstract available


  83. SHI C, Yang EJ, Liu Y, Mou PK, et al
    Bromodomain and extra-terminal motif (BET) inhibition is synthetic lethal with loss of SMAD4 in colorectal cancer cells via restoring the loss of MYC repression.
    Oncogene. 2020 Dec 8. pii: 10.1038/s41388-020-01580.
    PubMed     Abstract available


    November 2020
  84. BECK M, Baranger M, Moufok-Sadoun A, Bersuder E, et al
    The atypical cadherin MUCDHL antagonizes colon cancer formation and inhibits oncogenic signaling through multiple mechanisms.
    Oncogene. 2020 Nov 13. pii: 10.1038/s41388-020-01546.
    PubMed     Abstract available


  85. XU L, Huan L, Guo T, Wu Y, et al
    LncRNA SNHG11 facilitates tumor metastasis by interacting with and stabilizing HIF-1alpha.
    Oncogene. 2020;39:7005-7018.
    PubMed     Abstract available


    September 2020
  86. PENG K, Zhuo M, Li M, Chen Q, et al
    Histone demethylase JMJD2D activates HIF1 signaling pathway via multiple mechanisms to promote colorectal cancer glycolysis and progression.
    Oncogene. 2020 Sep 28. pii: 10.1038/s41388-020-01483.
    PubMed     Abstract available


  87. GAN T, Stevens AT, Xiong X, Wen YA, et al
    Inhibition of protein tyrosine phosphatase receptor type F suppresses Wnt signaling in colorectal cancer.
    Oncogene. 2020 Sep 24. pii: 10.1038/s41388-020-01472.
    PubMed     Abstract available


  88. JIN G, Yan M, Liu K, Yao K, et al
    Discovery of a novel dual-target inhibitor against RSK1 and MSK2 to suppress growth of human colon cancer.
    Oncogene. 2020 Sep 22. pii: 10.1038/s41388-020-01467.
    PubMed     Abstract available


  89. REISCHMANN N, Andrieux G, Griffin R, Reinheckel T, et al
    BRAF(V600E) drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation.
    Oncogene. 2020;39:6053-6070.
    PubMed     Abstract available


    August 2020
  90. BRAGGIO D, Zewdu A, Londhe P, Yu P, et al
    beta-catenin S45F mutation results in apoptotic resistance.
    Oncogene. 2020;39:5589-5600.
    PubMed     Abstract available


    May 2020
  91. PARK SM, Hwang CY, Choi J, Joung CY, et al
    Feedback analysis identifies a combination target for overcoming adaptive resistance to targeted cancer therapy.
    Oncogene. 2020;39:3803-3820.
    PubMed     Abstract available


  92. YU L, Dong L, Li H, Liu Z, et al
    Ubiquitination-mediated degradation of SIRT1 by SMURF2 suppresses CRC cell proliferation and tumorigenesis.
    Oncogene. 2020;39:4450-4464.
    PubMed     Abstract available


    April 2020
  93. LI S, Lavrijsen M, Bakker A, Magierowski M, et al
    Commonly observed RNF43 mutations retain functionality in attenuating Wnt/beta-catenin signaling and unlikely confer Wnt-dependency onto colorectal cancers.
    Oncogene. 2020;39:3458-3472.
    PubMed     Abstract available


  94. ZHUO M, Chen W, Shang S, Guo P, et al
    Inflammation-induced JMJD2D promotes colitis recovery and colon tumorigenesis by activating Hedgehog signaling.
    Oncogene. 2020;39:3336-3353.
    PubMed     Abstract available


  95. KATO H, Asamitsu K, Sun W, Kitajima S, et al
    Cancer-derived UTX TPR mutations G137V and D336G impair interaction with MLL3/4 complexes and affect UTX subcellular localization.
    Oncogene. 2020;39:3322-3335.
    PubMed     Abstract available


    March 2020
  96. LI L, Liu J, Xue H, Li C, et al
    A TGF-beta-MTA1-SOX4-EZH2 signaling axis drives epithelial-mesenchymal transition in tumor metastasis.
    Oncogene. 2020;39:2125-2139.
    PubMed     Abstract available


    February 2020
  97. WANG X, Wang Y, Li L, Xue X, et al
    A lncRNA coordinates with Ezh2 to inhibit HIF-1alpha transcription and suppress cancer cell adaption to hypoxia.
    Oncogene. 2020;39:1860-1874.
    PubMed     Abstract available


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