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Explore this week’s CC Journal Club

90‑sec video • 4‑min audio • paper abstracts

This week, 27 April 2025:

  1. Treatment-resistant hypertension
  2. Influenza transmission
  3. Nanoplastics in human brains
  4. Malaria elimination
  5. Chikungunya vaccine

  Colorectal Neoplasms

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Articles published in Oncogene

Retrieve available abstracts of 28 articles:
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Single Articles


    April 2025
  1. WOUTERS VM, Helderman RFCPA, Cameron K, van der Hooff SR, et al
    CDX2 downregulation regulates intrinsic WNT pathway activation, dictating metastasis in APC and CTNNB1 wildtype colorectal cancer.
    Oncogene. 2025 Apr 6. doi: 10.1038/s41388-025-03365.
    PubMed     Abstract available


    March 2025
  2. TAIRA A, Aavikko M, Katainen R, Kaasinen E, et al
    Comprehensive metabolomic and epigenomic characterization of microsatellite stable BRAF-mutated colorectal cancer.
    Oncogene. 2025 Mar 18. doi: 10.1038/s41388-025-03326.
    PubMed     Abstract available


  3. WANG B, Zhang S, Guo Y, Gao W, et al
    CBX2 as a therapeutic target in colorectal cancer: insights into the altered chromatin accessibility via RUNX1-CBX2-MAP4K1 axis.
    Oncogene. 2025 Mar 13. doi: 10.1038/s41388-025-03331.
    PubMed     Abstract available


    February 2025
  4. SHENG Z, Luo S, Huang L, Deng YN, et al
    SENP1-mediated deSUMOylation of YBX1 promotes colorectal cancer development through the SENP1-YBX1-AKT signaling axis.
    Oncogene. 2025 Feb 23. doi: 10.1038/s41388-025-03302.
    PubMed     Abstract available


  5. YAN Z, He L, Yuan J, Niu Y, et al
    The splicing factor SRRM2 modulates two S6K kinases to promote colorectal cancer growth.
    Oncogene. 2025 Feb 16. doi: 10.1038/s41388-025-03307.
    PubMed     Abstract available


  6. ZHANG J, Zhai J, Wong CC, Chen H, et al
    Correction: A novel amplification gene PCI domain containing 2 (PCID2) promotes colorectal cancer through directly degrading a tumor suppressor promyelocytic leukemia (PML).
    Oncogene. 2025 Feb 12. doi: 10.1038/s41388-025-03304.
    PubMed    


  7. RUAN DY, Li T, Wang YN, Meng Q, et al
    Correction: FTO downregulation mediated by hypoxia facilitates colorectal cancer metastasis.
    Oncogene. 2025 Feb 4. doi: 10.1038/s41388-025-03287.
    PubMed    


    January 2025
  8. REISSLAND M, Hartmann O, Tauch S, Bugter JM, et al
    Correction: USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer.
    Oncogene. 2025 Jan 22. doi: 10.1038/s41388-024-03262.
    PubMed    


    December 2024
  9. LIAO Y, Yang R, Wang B, Ruan Y, et al
    Mevalonate kinase inhibits anti-tumor immunity by impairing the tumor cell-intrinsic interferon response in microsatellite instability colorectal cancer.
    Oncogene. 2024 Dec 26. doi: 10.1038/s41388-024-03255.
    PubMed     Abstract available


    November 2024
  10. ZHUANG M, Liu J, Li Y, Zhang J, et al
    PD-L1 promotes tumor metastasis by regulating the infiltration of FGFBP2(+)Tm cells in colorectal cancer.
    Oncogene. 2024 Nov 18. doi: 10.1038/s41388-024-03223.
    PubMed     Abstract available


  11. WEN M, Qiu Y, Wang M, Tang F, et al
    Enhancing low-dose radiotherapy efficacy with PARP inhibitors via FBL-mediated oxidative stress response in colorectal cancer.
    Oncogene. 2024 Nov 8. doi: 10.1038/s41388-024-03207.
    PubMed     Abstract available


  12. DUYSAK T, Kim K, Yun M, Jeong JH, et al
    Enhanced anti-cancer efficacy of arginine deaminase expressed by tumor-seeking Salmonella Gallinarum.
    Oncogene. 2024;43:3378-3387.
    PubMed     Abstract available


  13. BORDONE R, Ivy DM, D'Amico R, Barba M, et al
    MYC upstream region orchestrates resistance to PI3K inhibitors in cancer cells through FOXO3a-mediated autophagic adaptation.
    Oncogene. 2024;43:3349-3365.
    PubMed     Abstract available


    October 2024
  14. BORDING T, Janik T, Bischoff P, Morkel M, et al
    GPA33 expression in colorectal cancer can be induced by WNT inhibition and targeted by cellular therapy.
    Oncogene. 2024 Oct 29. doi: 10.1038/s41388-024-03200.
    PubMed     Abstract available


  15. REISSLAND M, Hartmann O, Tauch S, Bugter JM, et al
    USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer.
    Oncogene. 2024 Oct 23. doi: 10.1038/s41388-024-03141.
    PubMed     Abstract available


  16. LIN W, Xu L, Li Y, Li J, et al
    Aberrant FAM135B attenuates the efficacy of chemotherapy in colorectal cancer by modulating SRSF1-mediated alternative splicing.
    Oncogene. 2024 Oct 13. doi: 10.1038/s41388-024-03189.
    PubMed     Abstract available


  17. HAN F, Zhou X, Liu L, Yang B, et al
    GLTSCR1 deficiency promotes colorectal cancer development through regulating non-homologous end joining.
    Oncogene. 2024 Oct 11. doi: 10.1038/s41388-024-03179.
    PubMed     Abstract available


    September 2024
  18. XU H, Wang T, Nie H, Sun Q, et al
    USP36 promotes colorectal cancer progression through inhibition of p53 signaling pathway via stabilizing RBM28.
    Oncogene. 2024 Sep 29. doi: 10.1038/s41388-024-03178.
    PubMed     Abstract available


  19. SUN Z, Dang P, Guo Y, Liu S, et al
    Targeting CircAURKA prevents colorectal cancer progression via enhancing CTNNB1 protein degradation.
    Oncogene. 2024 Sep 28. doi: 10.1038/s41388-024-03155.
    PubMed     Abstract available


  20. TANG W, Yang Y, Fu Z, Xu W, et al
    The RNA helicase DDX21 activates YAP to promote tumorigenesis and is transcriptionally upregulated by beta-catenin in colorectal cancer.
    Oncogene. 2024 Sep 17. doi: 10.1038/s41388-024-03160.
    PubMed     Abstract available


  21. CHURCHHOUSE AMD, Billard CV, Suzuki T, Pohl SOG, et al
    Loss of DOCK2 potentiates Inflammatory Bowel Disease-associated colorectal cancer via immune dysfunction and IFNgamma induction of IDO1 expression.
    Oncogene. 2024 Sep 7. doi: 10.1038/s41388-024-03135.
    PubMed     Abstract available


    August 2024
  22. GUPTA A, Avadhanula S, Bashyam MD
    Evaluation of the gene fusion landscape in early onset sporadic rectal cancer reveals association with chromatin architecture and genome stability.
    Oncogene. 2024;43:2449-2462.
    PubMed     Abstract available


    July 2024
  23. LI X, Chen Y, Lu R, Hu M, et al
    Correction: Colorectal cancer cells secreting DKK4 transform fibroblasts to promote tumour metastasis.
    Oncogene. 2024 Jul 15. doi: 10.1038/s41388-024-03101.
    PubMed    


    June 2024
  24. GU J, Xu X, Li X, Yue L, et al
    Tumor-resident microbiota contributes to colorectal cancer liver metastasis by lactylation and immune modulation.
    Oncogene. 2024 Jun 18. doi: 10.1038/s41388-024-03080.
    PubMed     Abstract available


  25. FENG M, Chai C, Hao X, Lai X, et al
    Inherited KDM6A(A649T) facilitates tumor-immune escape and exacerbates colorectal signet-ring cell carcinoma outcomes.
    Oncogene. 2024;43:1757-1768.
    PubMed     Abstract available


    April 2024
  26. CAO N, Zhang F, Yin J, Zhang J, et al
    LPCAT2 inhibits colorectal cancer progression via the PRMT1/SLC7A11 axis.
    Oncogene. 2024 Apr 11. doi: 10.1038/s41388-024-02996.
    PubMed     Abstract available


  27. WU Q, Wang Z, Chen S, She X, et al
    USP26 promotes colorectal cancer tumorigenesis by restraining PRKN-mediated mitophagy.
    Oncogene. 2024 Apr 2. doi: 10.1038/s41388-024-03009.
    PubMed     Abstract available


    March 2024
  28. LI X, Chen Y, Lu R, Hu M, et al
    Colorectal cancer cells secreting DKK4 transform fibroblasts to promote tumour metastasis.
    Oncogene. 2024 Mar 22. doi: 10.1038/s41388-024-03008.
    PubMed     Abstract available


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