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Articles published in Oncogene

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    July 2021
  1. KOBELT D, Perez-Hernandez D, Fleuter C, Dahlmann M, et al
    The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis.
    Oncogene. 2021 Jul 10. pii: 10.1038/s41388-021-01917.
    PubMed     Abstract available

  2. RUAN DY, Li T, Wang YN, Meng Q, et al
    FTO downregulation mediated by hypoxia facilitates colorectal cancer metastasis.
    Oncogene. 2021 Jul 3. pii: 10.1038/s41388-021-01916.
    PubMed     Abstract available

    June 2021
  3. SUN L, Patai AV, Hogenson TL, Fernandez-Zapico ME, et al
    Irreversible JNK blockade overcomes PD-L1-mediated resistance to chemotherapy in colorectal cancer.
    Oncogene. 2021 Jun 30. pii: 10.1038/s41388-021-01910.
    PubMed     Abstract available

  4. ZHAO S, Guan B, Mi Y, Shi D, et al
    LncRNA MIR17HG promotes colorectal cancer liver metastasis by mediating a glycolysis-associated positive feedback circuit.
    Oncogene. 2021 Jun 18. pii: 10.1038/s41388-021-01859.
    PubMed     Abstract available

  5. WANG H, Wang X, Zhang H, Deng T, et al
    The HSF1/miR-135b-5p axis induces protective autophagy to promote oxaliplatin resistance through the MUL1/ULK1 pathway in colorectal cancer.
    Oncogene. 2021 Jun 17. pii: 10.1038/s41388-021-01898.
    PubMed     Abstract available

  6. MCANDREWS KM, Vazquez-Arreguin K, Kwak C, Sugimoto H, et al
    alphaSMA(+) fibroblasts suppress Lgr5(+) cancer stem cells and restrain colorectal cancer progression.
    Oncogene. 2021 Jun 9. pii: 10.1038/s41388-021-01866.
    PubMed     Abstract available

  7. MALKOMES P, Lunger I, Oppermann E, Abou-El-Ardat K, et al
    Transglutaminase 2 promotes tumorigenicity of colon cancer cells by inactivation of the tumor suppressor p53.
    Oncogene. 2021 Jun 8. pii: 10.1038/s41388-021-01847.
    PubMed     Abstract available

    May 2021
  8. YOU J, Li J, Ke C, Xiao Y, et al
    Oncogenic long intervening noncoding RNA Linc00284 promotes c-Met expression by sponging miR-27a in colorectal cancer.
    Oncogene. 2021 May 28. pii: 10.1038/s41388-021-01839.
    PubMed     Abstract available

  9. CHEN J, Na R, Xiao C, Wang X, et al
    The loss of SHMT2 mediates 5-fluorouracil chemoresistance in colorectal cancer by upregulating autophagy.
    Oncogene. 2021 May 14. pii: 10.1038/s41388-021-01815.
    PubMed     Abstract available

  10. ZHANG XL, Hu LP, Yang Q, Qin WT, et al
    CTHRC1 promotes liver metastasis by reshaping infiltrated macrophages through physical interactions with TGF-beta receptors in colorectal cancer.
    Oncogene. 2021 May 13. pii: 10.1038/s41388-021-01827.
    PubMed     Abstract available

  11. ZENG K, Chen X, Hu X, Liu X, et al
    Correction: LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation.
    Oncogene. 2021 May 6. pii: 10.1038/s41388-021-01795.

    April 2021
  12. LIU J, Huang Z, Chen HN, Qin S, et al
    ZNF37A promotes tumor metastasis through transcriptional control of THSD4/TGF-beta axis in colorectal cancer.
    Oncogene. 2021 Apr 19. pii: 10.1038/s41388-021-01713.
    PubMed     Abstract available

  13. XIAO Q, Gan Y, Li Y, Fan L, et al
    MEF2A transcriptionally upregulates the expression of ZEB2 and CTNNB1 in colorectal cancer to promote tumor progression.
    Oncogene. 2021 Apr 16. pii: 10.1038/s41388-021-01774.
    PubMed     Abstract available

    March 2021
  14. CHUEH AC, Advani G, Foroutan M, Smith J, et al
    CSK-homologous kinase (CHK/MATK) is a potential colorectal cancer tumour suppressor gene epigenetically silenced by promoter methylation.
    Oncogene. 2021 Mar 25. pii: 10.1038/s41388-021-01755.
    PubMed     Abstract available

    February 2021
  15. CUI K, Yao S, Zhang H, Zhou M, et al
    Identification of an immune overdrive high-risk subpopulation with aberrant expression of FOXP3 and CTLA4 in colorectal cancer.
    Oncogene. 2021 Feb 24. pii: 10.1038/s41388-021-01677.
    PubMed     Abstract available

  16. PENG K, Zhuo M, Li M, Chen Q, et al
    Correction to: Histone demethylase JMJD2D activates HIF1 signaling pathway via multiple mechanisms to promote colorectal cancer glycolysis and progression.
    Oncogene. 2021 Feb 22. pii: 10.1038/s41388-021-01678.

  17. XU H, Liu L, Li W, Zou D, et al
    Correction: Transcription factors in colorectal cancer: molecular mechanism and therapeutic implications.
    Oncogene. 2021 Feb 9. pii: 10.1038/s41388-021-01651.

    January 2021
  18. YIN XK, Wang YL, Wang F, Feng WX, et al
    PRMT1 enhances oncogenic arginine methylation of NONO in colorectal cancer.
    Oncogene. 2021 Jan 8. pii: 10.1038/s41388-020-01617.
    PubMed     Abstract available

  19. LI H, Zhao L, Lau YS, Zhang C, et al
    Genome-wide CRISPR screen identifies LGALS2 as an oxidative stress-responsive gene with an inhibitory function on colon tumor growth.
    Oncogene. 2021;40:177-188.
    PubMed     Abstract available

  20. GIRONDEL C, Levesque K, Langlois MJ, Pasquin S, et al
    Loss of interleukin-17 receptor D promotes chronic inflammation-associated tumorigenesis.
    Oncogene. 2021;40:452-464.
    PubMed     Abstract available

  21. SCHMIDT AK, Pudelko K, Boekenkamp JE, Berger K, et al
    The p53/p73 - p21(CIP1) tumor suppressor axis guards against chromosomal instability by restraining CDK1 in human cancer cells.
    Oncogene. 2021;40:436-451.
    PubMed     Abstract available

    December 2020
  22. XU H, Liu L, Li W, Zou D, et al
    Transcription factors in colorectal cancer: molecular mechanism and therapeutic implications.
    Oncogene. 2020 Dec 15. pii: 10.1038/s41388-020-01587.
    PubMed     Abstract available

  23. BERGIN CJ, Zouggar A, Haebe JR, Masibag AN, et al
    G9a controls pluripotent-like identity and tumor-initiating function in human colorectal cancer.
    Oncogene. 2020 Dec 15. pii: 10.1038/s41388-020-01591.
    PubMed     Abstract available

  24. SHI C, Yang EJ, Liu Y, Mou PK, et al
    Bromodomain and extra-terminal motif (BET) inhibition is synthetic lethal with loss of SMAD4 in colorectal cancer cells via restoring the loss of MYC repression.
    Oncogene. 2020 Dec 8. pii: 10.1038/s41388-020-01580.
    PubMed     Abstract available

    November 2020
  25. BECK M, Baranger M, Moufok-Sadoun A, Bersuder E, et al
    The atypical cadherin MUCDHL antagonizes colon cancer formation and inhibits oncogenic signaling through multiple mechanisms.
    Oncogene. 2020 Nov 13. pii: 10.1038/s41388-020-01546.
    PubMed     Abstract available

  26. XU L, Huan L, Guo T, Wu Y, et al
    LncRNA SNHG11 facilitates tumor metastasis by interacting with and stabilizing HIF-1alpha.
    Oncogene. 2020;39:7005-7018.
    PubMed     Abstract available

    September 2020
  27. PENG K, Zhuo M, Li M, Chen Q, et al
    Histone demethylase JMJD2D activates HIF1 signaling pathway via multiple mechanisms to promote colorectal cancer glycolysis and progression.
    Oncogene. 2020 Sep 28. pii: 10.1038/s41388-020-01483.
    PubMed     Abstract available

  28. GAN T, Stevens AT, Xiong X, Wen YA, et al
    Inhibition of protein tyrosine phosphatase receptor type F suppresses Wnt signaling in colorectal cancer.
    Oncogene. 2020 Sep 24. pii: 10.1038/s41388-020-01472.
    PubMed     Abstract available

  29. JIN G, Yan M, Liu K, Yao K, et al
    Discovery of a novel dual-target inhibitor against RSK1 and MSK2 to suppress growth of human colon cancer.
    Oncogene. 2020 Sep 22. pii: 10.1038/s41388-020-01467.
    PubMed     Abstract available

  30. REISCHMANN N, Andrieux G, Griffin R, Reinheckel T, et al
    BRAF(V600E) drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation.
    Oncogene. 2020;39:6053-6070.
    PubMed     Abstract available

    August 2020
  31. BARTOLOME RA, Pintado-Berninches L, Jaen M, de Los Rios V, et al
    SOSTDC1 promotes invasion and liver metastasis in colorectal cancer via interaction with ALCAM/CD166.
    Oncogene. 2020 Aug 15. pii: 10.1038/s41388-020-01419.
    PubMed     Abstract available

  32. CAI J, Liu W, Wong CW, Zhu W, et al
    Zinc-finger antiviral protein acts as a tumor suppressor in colorectal cancer.
    Oncogene. 2020 Aug 7. pii: 10.1038/s41388-020-01416.
    PubMed     Abstract available

  33. BRAGGIO D, Zewdu A, Londhe P, Yu P, et al
    beta-catenin S45F mutation results in apoptotic resistance.
    Oncogene. 2020;39:5589-5600.
    PubMed     Abstract available

    July 2020
  34. YAN P, Liu J, Zhou R, Lin C, et al
    LASP1 interacts with N-WASP to activate the Arp2/3 complex and facilitate colorectal cancer metastasis by increasing tumour budding and worsening the pattern of invasion.
    Oncogene. 2020 Jul 23. pii: 10.1038/s41388-020-01397.
    PubMed     Abstract available

    June 2020
  35. ZHANG YH, Shi WN, Wu SH, Miao RR, et al
    SphK2 confers 5-fluorouracil resistance to colorectal cancer via upregulating H3K56ac-mediated DPD expression.
    Oncogene. 2020 Jun 16. pii: 10.1038/s41388-020-1352.
    PubMed     Abstract available

  36. YI H, Li G, Long Y, Liang W, et al
    Integrative multi-omics analysis of a colon cancer cell line with heterogeneous Wnt activity revealed RUNX2 as an epigenetic regulator of EMT.
    Oncogene. 2020 Jun 13. pii: 10.1038/s41388-020-1351.
    PubMed     Abstract available

  37. FONG W, Li Q, Yu J
    Gut microbiota modulation: a novel strategy for prevention and treatment of colorectal cancer.
    Oncogene. 2020 Jun 8. pii: 10.1038/s41388-020-1341.
    PubMed     Abstract available

    May 2020
  38. ZHU Z, Song J, Guo Y, Huang Z, et al
    LAMB3 promotes tumour progression through the AKT-FOXO3/4 axis and is transcriptionally regulated by the BRD2/acetylated ELK4 complex in colorectal cancer.
    Oncogene. 2020 May 12. pii: 10.1038/s41388-020-1321.
    PubMed     Abstract available

  39. PARK SM, Hwang CY, Choi J, Joung CY, et al
    Feedback analysis identifies a combination target for overcoming adaptive resistance to targeted cancer therapy.
    Oncogene. 2020;39:3803-3820.
    PubMed     Abstract available

  40. YU L, Dong L, Li H, Liu Z, et al
    Ubiquitination-mediated degradation of SIRT1 by SMURF2 suppresses CRC cell proliferation and tumorigenesis.
    Oncogene. 2020;39:4450-4464.
    PubMed     Abstract available

    April 2020
  41. TIAN Q, Yuan P, Quan C, Li M, et al
    Phosphorylation of BCKDK of BCAA catabolism at Y246 by Src promotes metastasis of colorectal cancer.
    Oncogene. 2020 Apr 1. pii: 10.1038/s41388-020-1262.
    PubMed     Abstract available

  42. LI S, Lavrijsen M, Bakker A, Magierowski M, et al
    Commonly observed RNF43 mutations retain functionality in attenuating Wnt/beta-catenin signaling and unlikely confer Wnt-dependency onto colorectal cancers.
    Oncogene. 2020;39:3458-3472.
    PubMed     Abstract available

  43. ZHUO M, Chen W, Shang S, Guo P, et al
    Inflammation-induced JMJD2D promotes colitis recovery and colon tumorigenesis by activating Hedgehog signaling.
    Oncogene. 2020;39:3336-3353.
    PubMed     Abstract available

  44. KATO H, Asamitsu K, Sun W, Kitajima S, et al
    Cancer-derived UTX TPR mutations G137V and D336G impair interaction with MLL3/4 complexes and affect UTX subcellular localization.
    Oncogene. 2020;39:3322-3335.
    PubMed     Abstract available

    March 2020
  45. GAO Q, Zhou R, Meng Y, Duan R, et al
    Long noncoding RNA CMPK2 promotes colorectal cancer progression by activating the FUBP3-c-Myc axis.
    Oncogene. 2020 Mar 20. pii: 10.1038/s41388-020-1266.
    PubMed     Abstract available

  46. WENZEL J, Rose K, Haghighi EB, Lamprecht C, et al
    Loss of the nuclear Wnt pathway effector TCF7L2 promotes migration and invasion of human colorectal cancer cells.
    Oncogene. 2020 Mar 20. pii: 10.1038/s41388-020-1259.
    PubMed     Abstract available

  47. HE Z, Thorrez L, Siegfried G, Meulemans S, et al
    The proprotein convertase furin is a pro-oncogenic driver in KRAS and BRAF driven colorectal cancer.
    Oncogene. 2020 Mar 6. pii: 10.1038/s41388-020-1238.
    PubMed     Abstract available

  48. LI L, Liu J, Xue H, Li C, et al
    A TGF-beta-MTA1-SOX4-EZH2 signaling axis drives epithelial-mesenchymal transition in tumor metastasis.
    Oncogene. 2020;39:2125-2139.
    PubMed     Abstract available

    February 2020
  49. DU F, Li X, Feng W, Qiao C, et al
    SOX13 promotes colorectal cancer metastasis by transactivating SNAI2 and c-MET.
    Oncogene. 2020 Feb 28. pii: 10.1038/s41388-020-1233.
    PubMed     Abstract available

  50. WANG X, Wang Y, Li L, Xue X, et al
    A lncRNA coordinates with Ezh2 to inhibit HIF-1alpha transcription and suppress cancer cell adaption to hypoxia.
    Oncogene. 2020;39:1860-1874.
    PubMed     Abstract available

    January 2020
  51. OUAHOUD S, Voorneveld PW, van der Burg LRA, de Jonge-Muller ESM, et al
    Bidirectional tumor/stroma crosstalk promotes metastasis in mesenchymal colorectal cancer.
    Oncogene. 2020 Jan 23. pii: 10.1038/s41388-020-1157.
    PubMed     Abstract available

    December 2019
  52. RIPANI P, Delp J, Bode K, Delgado ME, et al
    Thiazolides promote G1 cell cycle arrest in colorectal cancer cells by targeting the mitochondrial respiratory chain.
    Oncogene. 2019 Dec 16. pii: 10.1038/s41388-019-1142.
    PubMed     Abstract available

  53. ZHOU B, Zong S, Zhong W, Tian Y, et al
    Correction: Interaction between laminin-5gamma2 and integrin beta1 promotes the tumor budding of colorectal cancer via the activation of Yes-associated proteins.
    Oncogene. 2019 Dec 4. pii: 10.1038/s41388-019-1113.
    PubMed     Abstract available

  54. KO YS, Bae JA, Kim KY, Kim SJ, et al
    MYO1D binds with kinase domain of the EGFR family to anchor them to plasma membrane before their activation and contributes carcinogenesis.
    Oncogene. 2019;38:7416-7432.
    PubMed     Abstract available

    November 2019
  55. ZHOU B, Zong S, Zhong W, Tian Y, et al
    Interaction between laminin-5gamma2 and integrin beta1 promotes the tumor budding of colorectal cancer via the activation of Yes-associated proteins.
    Oncogene. 2019 Nov 1. pii: 10.1038/s41388-019-1082.
    PubMed     Abstract available

  56. SHENG YH, Wong KY, Seim I, Wang R, et al
    MUC13 promotes the development of colitis-associated colorectal tumors via beta-catenin activity.
    Oncogene. 2019;38:7294-7310.
    PubMed     Abstract available

  57. KOH XY, Koh XH, Hwang LA, Ferrer FJ, et al
    Therapeutic anti-cancer activity of antibodies targeting sulfhydryl bond constrained epitopes on unglycosylated RON receptor tyrosine kinase.
    Oncogene. 2019;38:7342-7356.
    PubMed     Abstract available

    October 2019
  58. YU CY, Han JX, Zhang J, Jiang P, et al
    A 16q22.1 variant confers susceptibility to colorectal cancer as a distal regulator of ZFP90.
    Oncogene. 2019 Oct 22. pii: 10.1038/s41388-019-1055.
    PubMed     Abstract available

  59. LIANG Y, Hou L, Li L, Li L, et al
    Dichloroacetate restores colorectal cancer chemosensitivity through the p53/miR-149-3p/PDK2-mediated glucose metabolic pathway.
    Oncogene. 2019 Oct 9. pii: 10.1038/s41388-019-1035.
    PubMed     Abstract available

  60. YING Y, Wang Y, Huang X, Sun Y, et al
    Oncogenic HOXB8 is driven by MYC-regulated super-enhancer and potentiates colorectal cancer invasiveness via BACH1.
    Oncogene. 2019 Oct 7. pii: 10.1038/s41388-019-1013.
    PubMed     Abstract available

  61. VESCHI V, Mangiapane LR, Nicotra A, Di Franco S, et al
    Targeting chemoresistant colorectal cancer via systemic administration of a BMP7 variant.
    Oncogene. 2019 Oct 7. pii: 10.1038/s41388-019-1047.
    PubMed     Abstract available

  62. TANIUE K, Hayashi T, Kamoshida Y, Kurimoto A, et al
    UHRF1-KAT7-mediated regulation of TUSC3 expression via histone methylation/acetylation is critical for the proliferation of colon cancer cells.
    Oncogene. 2019 Oct 3. pii: 10.1038/s41388-019-1032.
    PubMed     Abstract available

    September 2019
  63. WANG YN, Lu YX, Liu J, Jin Y, et al
    AMPKalpha1 confers survival advantage of colorectal cancer cells under metabolic stress by promoting redox balance through the regulation of glutathione reductase phosphorylation.
    Oncogene. 2019 Sep 17. pii: 10.1038/s41388-019-1004.
    PubMed     Abstract available

  64. WEI TT, Lin YT, Tang SP, Luo CK, et al
    Metabolic targeting of HIF-1alpha potentiates the therapeutic efficacy of oxaliplatin in colorectal cancer.
    Oncogene. 2019 Sep 2. pii: 10.1038/s41388-019-0999.
    PubMed     Abstract available

  65. YANG S, Ren X, Liang Y, Yan Y, et al
    KNK437 restricts the growth and metastasis of colorectal cancer via targeting DNAJA1/CDC45 axis.
    Oncogene. 2019 Sep 2. pii: 10.1038/s41388-019-0978.
    PubMed     Abstract available

    August 2019
  66. HE Y, Davies CM, Harrington BS, Hellmers L, et al
    CDCP1 enhances Wnt signaling in colorectal cancer promoting nuclear localization of beta-catenin and E-cadherin.
    Oncogene. 2019 Aug 30. pii: 10.1038/s41388-019-0983.
    PubMed     Abstract available

  67. HYE PARK S, Jeong S, Ram Kim B, Jeong YA, et al
    Activating CCT2 triggers Gli-1 activation during hypoxic condition in colorectal cancer.
    Oncogene. 2019 Aug 28. pii: 10.1038/s41388-019-0972.
    PubMed     Abstract available

  68. FENG D, Qin B, Pal K, Sun L, et al
    BRAF(V600E)-induced, tumor intrinsic PD-L1 can regulate chemotherapy-induced apoptosis in human colon cancer cells and in tumor xenografts.
    Oncogene. 2019 Aug 12. pii: 10.1038/s41388-019-0919.
    PubMed     Abstract available

  69. BEYES S, Andrieux G, Schrempp M, Aicher D, et al
    Genome-wide mapping of DNA-binding sites identifies stemness-related genes as directly repressed targets of SNAIL1 in colorectal cancer cells.
    Oncogene. 2019 Aug 7. pii: 10.1038/s41388-019-0905.
    PubMed     Abstract available

  70. BERG KCG, Sveen A, Holand M, Alagaratnam S, et al
    Gene expression profiles of CMS2-epithelial/canonical colorectal cancers are largely driven by DNA copy number gains.
    Oncogene. 2019;38:6109-6122.
    PubMed     Abstract available

    July 2019
  71. HU YB, Yan C, Mu L, Mi YL, et al
    Correction: Exosomal Wnt-induced dedifferentiation of colorectal cancer cells contributes to chemotherapy resistance.
    Oncogene. 2019 Jul 31. pii: 10.1038/s41388-019-0863.
    PubMed     Abstract available

  72. CHEN D, Li Y, Zhang X, Wu H, et al
    Ubiquitin ligase TRIM65 promotes colorectal cancer metastasis by targeting ARHGAP35 for protein degradation.
    Oncogene. 2019 Jul 22. pii: 10.1038/s41388-019-0891.
    PubMed     Abstract available

  73. CHEN Z, Ren R, Wan D, Wang Y, et al
    Hsa_circ_101555 functions as a competing endogenous RNA of miR-597-5p to promote colorectal cancer progression.
    Oncogene. 2019 Jul 12. pii: 10.1038/s41388-019-0857.
    PubMed     Abstract available

  74. OHSUGI T, Yamaguchi K, Zhu C, Ikenoue T, et al
    Anti-apoptotic effect by the suppression of IRF1 as a downstream of Wnt/beta-catenin signaling in colorectal cancer cells.
    Oncogene. 2019 Jul 10. pii: 10.1038/s41388-019-0856.
    PubMed     Abstract available

  75. ROHWER N, Jumpertz S, Erdem M, Egners A, et al
    Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis.
    Oncogene. 2019;38:5670-5685.
    PubMed     Abstract available

    June 2019
  76. MISHRA S, Bernal C, Silvano M, Anand S, et al
    The protein secretion modulator TMED9 drives CNIH4/TGFalpha/GLI signaling opposing TMED3-WNT-TCF to promote colon cancer metastases.
    Oncogene. 2019 Jun 28. pii: 10.1038/s41388-019-0845.
    PubMed     Abstract available

  77. JIANG M, Xu B, Li X, Shang Y, et al
    Correction: O-GlcNAcylation promotes colorectal cancer metastasis via the miR-101-O-GlcNAc/EZH2 regulatory feedback circuit.
    Oncogene. 2019 Jun 3. pii: 10.1038/s41388-019-0834.
    PubMed     Abstract available

  78. GOWRIKUMAR S, Ahmad R, Uppada SB, Washington MK, et al
    Upregulated claudin-1 expression promotes colitis-associated cancer by promoting beta-catenin phosphorylation and activation in Notch/p-AKT-dependent manner.
    Oncogene. 2019;38:5321-5337.
    PubMed     Abstract available

  79. SHORT SP, Barrett CW, Stengel KR, Revetta FL, et al
    Kaiso is required for MTG16-dependent effects on colitis-associated carcinoma.
    Oncogene. 2019;38:5091-5106.
    PubMed     Abstract available

  80. SCHWIEBS A, Herrero San Juan M, Schmidt KG, Wiercinska E, et al
    Cancer-induced inflammation and inflammation-induced cancer in colon: a role for S1P lyase.
    Oncogene. 2019;38:4788-4803.
    PubMed     Abstract available

    May 2019
  81. WAGNER S, Vlachogiannis G, De Haven Brandon A, Valenti M, et al
    Correction: Suppression of interferon gene expression overcomes resistance to MEK inhibition in KRAS-mutant colorectal cancer.
    Oncogene. 2019 May 30. pii: 10.1038/s41388-019-0835.
    PubMed     Abstract available

  82. LI M, Tang Y, Li Q, Xiao M, et al
    Mono-ADP-ribosylation of H3R117 traps 5mC hydroxylase TET1 to impair demethylation of tumor suppressor gene TFPI2.
    Oncogene. 2019;38:3488-3503.
    PubMed     Abstract available

  83. YAMAZAKI D, Hasegawa A, Funato Y, Tran HN, et al
    Cnnm4 deficiency suppresses Ca(2+) signaling and promotes cell proliferation in the colon epithelia.
    Oncogene. 2019;38:3962-3969.
    PubMed     Abstract available

    April 2019
  84. HAN Q, Xu L, Lin W, Yao X, et al
    Long noncoding RNA CRCMSL suppresses tumor invasive and metastasis in colorectal carcinoma through nucleocytoplasmic shuttling of HMGB2.
    Oncogene. 2019;38:3019-3032.
    PubMed     Abstract available

    March 2019
  85. CLARKE PA, Roe T, Swabey K, Hobbs SM, et al
    Dissecting mechanisms of resistance to targeted drug combination therapy in human colorectal cancer.
    Oncogene. 2019 Mar 25. pii: 10.1038/s41388-019-0780.
    PubMed     Abstract available

  86. DE OLIVEIRA T, Ramakrishnan M, Diamanti MA, Ziegler PK, et al
    Loss of Stat6 affects chromatin condensation in intestinal epithelial cells causing diverse outcome in murine models of inflammation-associated and sporadic colon carcinogenesis.
    Oncogene. 2019;38:1787-1801.
    PubMed     Abstract available

    February 2019
  87. WANG T, Song P, Zhong T, Wang X, et al
    The inflammatory cytokine IL-6 induces FRA1 deacetylation promoting colorectal cancer stem-like properties.
    Oncogene. 2019 Feb 25. pii: 10.1038/s41388-019-0763.
    PubMed     Abstract available

  88. ZHAO GX, Xu YY, Weng SQ, Zhang S, et al
    CAPS1 promotes colorectal cancer metastasis via Snail mediated epithelial mesenchymal transformation.
    Oncogene. 2019 Feb 11. pii: 10.1038/s41388-019-0740.
    PubMed     Abstract available

  89. SONG ZY, Wang F, Cui SX, Gao ZH, et al
    CXCR7/CXCR4 heterodimer-induced histone demethylation: a new mechanism of colorectal tumorigenesis.
    Oncogene. 2019;38:1560-1575.
    PubMed     Abstract available

  90. HUANG X, Wang XN, Yuan XD, Wu WY, et al
    XIAP facilitates breast and colon carcinoma growth via promotion of p62 depletion through ubiquitination-dependent proteasomal degradation.
    Oncogene. 2019;38:1448-1460.
    PubMed     Abstract available

  91. COBURN LA, Singh K, Asim M, Barry DP, et al
    Loss of solute carrier family 7 member 2 exacerbates inflammation-associated colon tumorigenesis.
    Oncogene. 2019;38:1067-1079.
    PubMed     Abstract available

  92. MUNOZ-GALVAN S, Lucena-Cacace A, Perez M, Otero-Albiol D, et al
    Tumor cell-secreted PLD increases tumor stemness by senescence-mediated communication with microenvironment.
    Oncogene. 2019;38:1309-1323.
    PubMed     Abstract available

    January 2019
  93. KIM BR, Park SH, Jeong YA, Na YJ, et al
    RUNX3 enhances TRAIL-induced apoptosis by upregulating DR5 in colorectal cancer.
    Oncogene. 2019 Jan 28. pii: 10.1038/s41388-019-0693.
    PubMed     Abstract available

  94. GUHA P, Gardell J, Darpolor J, Cunetta M, et al
    STAT3 inhibition induces Bax-dependent apoptosis in liver tumor myeloid-derived suppressor cells.
    Oncogene. 2019;38:533-548.
    PubMed     Abstract available

  95. BAO Y, Guo Y, Yang Y, Wei X, et al
    PRSS8 suppresses colorectal carcinogenesis and metastasis.
    Oncogene. 2019;38:497-517.
    PubMed     Abstract available

    December 2018
  96. WIESWEG M, Kasper S, Worm K, Herold T, et al
    Impact of RAS mutation subtype on clinical outcome-a cross-entity comparison of patients with advanced non-small cell lung cancer and colorectal cancer.
    Oncogene. 2018 Dec 19. pii: 10.1038/s41388-018-0634.
    PubMed     Abstract available

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