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  Diabetes

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27.10.2025

1 Am J Cardiol
1 Am J Epidemiol
3 Ann Intern Med
1 Biochem Biophys Res Commun
1 BMC Pediatr
1 Br J Ophthalmol
1 Circ Cardiovasc Qual Outcomes
1 Circ Genom Precis Med
2 Diabet Med
9 Diabetes
15 Diabetes Care
5 Diabetes Obes Metab
5 Diabetologia
1 Invest Ophthalmol Vis Sci
1 J Autoimmun
3 J Diabetes Complications
2 Kidney Int
1 Metabolism
1 Ophthalmol Retina
1 PLoS Comput Biol
9 PLoS One
2 Retina
2 Transplantation


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Am J Cardiol

  1. HENKIN S, Piazza G
    GLP-1 Receptor Agonists in Patients with Diabetes and Peripheral Artery Disease - In Pursuit of Excellence.
    Am J Cardiol. 2025 Oct 15:S0002-9149(25)00643.
    PubMed        


    Am J Epidemiol

  2. KRASNOV H, Knobel P, Hsu HL, Teitelbaum SL, et al
    The association between long-term exposure to PM2.5 constituents and diabetes incidence and blood glucose levels among World Trade Center Health Program General Responders.
    Am J Epidemiol. 2025 Oct 23:kwaf238. doi: 10.1093.
    PubMed         Abstract available


    Ann Intern Med

  3. SHAHID M, Gandhi GY
    In early T2D inadequately controlled with diet and exercise, once-daily orforglipron reduced HbA(1c) vs. placebo at 40 wk.
    Ann Intern Med. 2025;178:JC114.
    PubMed         Abstract available

  4. TANNER M
    In insulin-naive T2D, fixed-dose weekly efsitora was noninferior to daily glargine for reducing HbA(1c) at 52 wk.
    Ann Intern Med. 2025;178:JC113.
    PubMed         Abstract available

  5. LAU D, Padwal R
    In T2D and hypertension, the lower-sodium DASH4D diet reduced SBP more than a higher-sodium comparison diet at 5 wk.
    Ann Intern Med. 2025;178:JC115.
    PubMed         Abstract available


    Biochem Biophys Res Commun

  6. WANG X, Pan W, Zhang M, Li Y, et al
    Diabetic retinopathy from the perspective of programmed cell death: Focusing on apoptosis, pyroptosis, and necroptosis.
    Biochem Biophys Res Commun. 2025;788:152829.
    PubMed         Abstract available


    BMC Pediatr

  7. AYCAN OK, Aksu SC
    Comparison of postpartum depression, anxiety, sleep quality and neonatal outcomes in mothers with pregestational and gestational diabetes.
    BMC Pediatr. 2025;25:845.
    PubMed         Abstract available


    Br J Ophthalmol

  8. XU X, Zhang J, Song X, Liu X, et al
    Enhancing diabetic retinopathy diagnosis and grading: a retrospective study on AI-assisted decision making and cost analysis.
    Br J Ophthalmol. 2025 Oct 20:bjo-2025-327442. doi: 10.1136/bjo-2025-327442.
    PubMed         Abstract available


    Circ Cardiovasc Qual Outcomes

  9. KENDZERSKA T, Saymeh M, Pugliese M, Povitz M, et al
    Trends in Health Care Services Use and Mortality in Adults With Cardiometabolic Diseases During the First Year of the Pandemic in Ontario, Canada.
    Circ Cardiovasc Qual Outcomes. 2025;18:e011996.
    PubMed         Abstract available


    Circ Genom Precis Med

  10. YADALAM AK, Liu C, Hui Q, Razavi AC, et al
    Large-Scale Proteomics-Based Risk Score for the Prediction of Incident Cardio-Kidney-Metabolic Disease Risk.
    Circ Genom Precis Med. 2025;18:e005125.
    PubMed         Abstract available


    Diabet Med

  11. GARGYA D, Chan V, Thrimawithana T, Ko KKH, et al
    Navigating cultural diversity in diabetes care: Insights from Australian healthcare professionals.
    Diabet Med. 2025 Oct 22:e70149. doi: 10.1111/dme.70149.
    PubMed         Abstract available

  12. STIMSON RH, Strachan MWJ, Forbes S, Wright RJ, et al
    Impact of Omnipod 5 automated insulin delivery on continuous glucose monitoring metrics and predictors of improvement in time in range.
    Diabet Med. 2025;42:e70137.
    PubMed         Abstract available


    Diabetes

  13. SRIRAM A, Wakeling MN, Hattersley AT, Weedon MN, et al
    Rare Variants in NEUROD1 and PDX1 Are Low-Penetrance Causes of MODY, Whereas Those in APPL1 and WFS1 Are Not Associated With MODY.
    Diabetes. 2025;74:2123-2131.
    PubMed         Abstract available

  14. BAI Z, Wang K, Yau T, Lim CKP, et al
    Effects of Dorzagliatin, a Glucokinase Activator, on alpha- and beta-Cell Function in Individuals With Impaired and Normal Glucose Tolerance.
    Diabetes. 2025;74:2111-2122.
    PubMed         Abstract available

  15. BLOM SE, Narsian PR, Behan-Bush RM, Ankrum JA, et al
    Proinflammatory Cytokines Mediate Pancreatic beta-Cell-Specific Alterations to Golgi Integrity via iNOS-Dependent Mitochondrial Inhibition.
    Diabetes. 2025;74:1992-2007.
    PubMed         Abstract available

  16. PAGE B
    Diabetes Spotlight: Kevin Williams, PhD-Mapping the Neural Networks of Metabolic Systems.
    Diabetes. 2025;74:1887-1888.
    PubMed        

  17. BRONS C, Elingaard-Larsen LO, Justesen L, Villumsen SO, et al
    Metabolic Perturbations and Ectopic Fat Deposition in Men With Low Birth Weight: Effects of a 4-Week Carbohydrate Overfeeding Challenge.
    Diabetes. 2025;74:2044-2059.
    PubMed         Abstract available

  18. AYALA JE
    Distributed Control of Muscle Glucose Uptake: A Tribute to the Late Dr. David H. Wasserman by Revisiting a 2004 Diabetes Classic by Fueger et al.
    Diabetes. 2025;74:1889-1891.
    PubMed         Abstract available

  19. CUBAS DIAZ EM, Fernandez Moreno DM, Saravia Paz Soldan CH
    Proteogenomic Insights Into Type 1 Diabetes: Refining Biomarkers and Therapeutic Targets.
    Diabetes. 2025;74:e13.
    PubMed        

  20. HOMANN D
    Sweating the Small Stuff: A Closer Look at the Endocrine Pancreas Throughout Stages of Type 1 Diabetes Progression.
    Diabetes. 2025;74:1895-1898.
    PubMed        

  21. GROEGLER J, Mangold K, Nicholson K, Dang M, et al
    Strategic Reduction of Hybrid Insulin Peptide Formation Significantly Delays Diabetes Onset in NOD Mice.
    Diabetes. 2025 Oct 21:db250324. doi: 10.2337/db25-0324.
    PubMed         Abstract available


    Diabetes Care

  22. TURNER LV, Sherr JL, Zaharieva DP, Baran J, et al
    Erratum. Use of the Omnipod 5 Automated Insulin Delivery System Activity Feature Reduces Insulin Delivery and Attenuates the Drop in Glycemia Associated With Exercise in a Randomized Controlled Trial Diabetes Care 2025;48:1598-1606.
    Diabetes Care. 2025 Oct 20:dc26er01a. doi: 10.2337.
    PubMed         Abstract available

  23. CHIESA ST, Jones S, Hughes AD, Katsoulis M, et al
    Comment on Agbaje et al. Persistent Hyperglycemia and Insulin Resistance With the Risk of Worsening Cardiac Damage in Adolescents: A 7-Year Longitudinal Study of the ALSPAC Birth Cohort. Diabetes Care 2025;48:896-904.
    Diabetes Care. 2025;48:e167-e168.
    PubMed        

  24. HASEBE M, Su CY
    Comment on Kofod et al. The Association Between Hemoglobin A1c and Complications Among Individuals With Diabetes and Severe Chronic Kidney Disease. Diabetes Care 2025;48:1400-1409.
    Diabetes Care. 2025;48:e156-e157.
    PubMed        

  25. SU CY, Hasebe M
    Comment on Gonzalez et al. Diabetes-Related Distress and Glycemic Dysregulation in Everyday Life With Type 1 Diabetes: Which Comes First? Diabetes Care 2025;48:1453-1460.
    Diabetes Care. 2025;48:e160-e161.
    PubMed        

  26. KUMAR A, Kuchay MS, Ghosh A, Gulati S, et al
    India-Specific Consensus on MASLD in Type 2 Diabetes: Bridging Global Guidelines to Local Realities.
    Diabetes Care. 2025;48:e153-e154.
    PubMed        

  27. NOSO S, Ikegami H
    Response to Comment on Noso et al. Rapid and Slow Progressors Toward beta-Cell Depletion and Their Predictors in Type 1 Diabetes: Prospective Longitudinal Study in Japanese Type 1 Diabetes (TIDE-J). Diabetes Care 2025;48:1438-1445.
    Diabetes Care. 2025;48:e165-e166.
    PubMed        

  28. KOFOD DH, Carlson N, Almdal TP, Bomholt T, et al
    Response to Comment on Kofod et al. The Association Between Hemoglobin A1c and Complications Among Individuals With Diabetes and Severe Chronic Kidney Disease. Diabetes Care 2025;48:1400-1409.
    Diabetes Care. 2025;48:e158-e159.
    PubMed        

  29. TAKEUCHI H, Mikamo T, Fukui M, Nagumo K, et al
    Comment on Noso et al. Rapid and Slow Progressors Toward beta-Cell Depletion and Their Predictors in Type 1 Diabetes: Prospective Longitudinal Study in Japanese Type 1 Diabetes (TIDE-J). Diabetes Care 2025;48:1438-1445.
    Diabetes Care. 2025;48:e164.
    PubMed        

  30. GONZALEZ JS, Hoogendoorn CJ, Hernandez R, Schneider S, et al
    Response to Comment on Gonzalez et al. Diabetes-Related Distress and Glycemic Dysregulation in Everyday Life With Type 1 Diabetes: Which Comes First? Diabetes Care 2025;48:1453-1460.
    Diabetes Care. 2025;48:e162-e163.
    PubMed        

  31. AGBAJE AO
    Response to Comment on Agbaje et al. Persistent Hyperglycemia and Insulin Resistance With the Risk of Worsening Cardiac Damage in Adolescents: A 7-Year Longitudinal Study of the ALSPAC Birth Cohort. Diabetes Care 2025;48:896-904.
    Diabetes Care. 2025;48:e169-e170.
    PubMed        

  32. CUSI K
    Our Common Goal to Prevent Cirrhosis in People With Type 2 Diabetes.
    Diabetes Care. 2025;48:e155.
    PubMed        

  33. AGARWAL R
    The FLOW of Progress in Diabetic Kidney Disease: Semaglutide's Role in Combination Therapy.
    Diabetes Care. 2025;48:1875-1877.
    PubMed        

  34. KOEGER M, Winkler C, Hummel S, Weiss A, et al
    Generalizability of Progression Risk in the TN-10 Trial to a European Population With or Without a First-Degree Relative With Type 1 Diabetes.
    Diabetes Care. 2025 Oct 21:dc251021. doi: 10.2337/dc25-1021.
    PubMed         Abstract available

  35. STATHI D, Nirmalakumaran A, Mangelis A, Collins J, et al
    The Impact of African Caribbean Heritage on the Development of Sight-Threatening Diabetic Retinopathy in a Multiethnic Cohort of People With Type 2 Diabetes.
    Diabetes Care. 2025 Oct 22:dc250910. doi: 10.2337/dc25-0910.
    PubMed         Abstract available

  36. BECKER M, Weiskorn J, Wiegand S, Robl M, et al
    Familial Hypercholesterolemia in Pediatric Patients With Type 1 Diabetes: Double Challenge for Diagnosis and Treatment.
    Diabetes Care. 2025 Oct 23:dc251195. doi: 10.2337/dc25-1195.
    PubMed         Abstract available


    Diabetes Obes Metab

  37. YU M
    iGlarLixi: A titrateable fixed-ratio combination of basal insulin + GLP-1 receptor agonist-An effective type 2 diabetes treatment option in China.
    Diabetes Obes Metab. 2025 Oct 20. doi: 10.1111/dom.70192.
    PubMed         Abstract available

  38. HIGHTON PJ, Funnell MP, Tziannou A, Rowlands AV, et al
    Structured group education programme and accompanying mHealth intervention to promote physical activity in women with a history of gestational diabetes (Baby Steps): 4-year follow-up of a randomised controlled trial.
    Diabetes Obes Metab. 2025 Oct 21. doi: 10.1111/dom.70199.
    PubMed        

  39. LIU Q, Guo S, Tong Y, Qiu L, et al
    Renal lipotoxicity in diabetic and obesity-associated kidney diseases: Molecular mechanisms and therapeutic targeting.
    Diabetes Obes Metab. 2025 Oct 22. doi: 10.1111/dom.70220.
    PubMed         Abstract available

  40. KATO S, Ozu N, Yamakage H, Kato H, et al
    Antidiabetic agents and dementia risk in type 2 diabetes: A systematic review and network meta-analysis.
    Diabetes Obes Metab. 2025 Oct 22. doi: 10.1111/dom.70182.
    PubMed         Abstract available

  41. ZHANG J, Wang Y, Lu Z, Yang Y, et al
    Baseline HbA1c and dementia risk at SGLT2i initiation in type 2 diabetes.
    Diabetes Obes Metab. 2025 Oct 20. doi: 10.1111/dom.70223.
    PubMed         Abstract available


    Diabetologia

  42. YUEN L, Hannah W, Hare M, Simmons D, et al
    Hyperglycaemia in pregnancy: the role of ethnicity and geography in risk and outcomes.
    Diabetologia. 2025;68:2340-2361.
    PubMed         Abstract available

  43. MISRA S
    Ethnic diversity in precision medicine: a reality or an aspiration?
    Diabetologia. 2025;68:2449-2464.
    PubMed         Abstract available

  44. DAVOODIAN N, Lotfaliany M, Huxley RR, Lee CMY, et al
    Regression from prediabetes to normoglycaemia and the role of cardiometabolic risk factors on the subsequent risk of developing type 2 diabetes.
    Diabetologia. 2025 Oct 18. doi: 10.1007/s00125-025-06555.
    PubMed         Abstract available

  45. ZHA D, Gamez J, Ebrahimi SM, Wang Y, et al
    Oxidative stress-regulatory role of miR-10b-5p in the diabetic human cornea revealed through integrated multi-omics analysis.
    Diabetologia. 2025 Oct 20. doi: 10.1007/s00125-025-06558.
    PubMed         Abstract available

  46. COLOMBIJN JMT, de Leijer JF, Visseren FLJ, Verhaar MC, et al
    Effectiveness and safety of combining SGLT2 inhibitors and GLP-1 receptor agonists in individuals with type 2 diabetes: a systematic review and meta-analysis of cohort studies.
    Diabetologia. 2025 Oct 21. doi: 10.1007/s00125-025-06565.
    PubMed         Abstract available


    Invest Ophthalmol Vis Sci

  47. VUORI N, Antikainen AA, Haukka JK, Harjutsalo V, et al
    Exome and Genome Sequencing Reveals Novel Variants for Severe Diabetic Retinopathy in Type 1 Diabetes.
    Invest Ophthalmol Vis Sci. 2025;66:36.
    PubMed         Abstract available


    J Autoimmun

  48. YEN FS, Wang SI, Hwu CM, Haung CW, et al
    Comparative risk of rheumatoid arthritis between glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter-2 inhibitors in type 2 diabetes.
    J Autoimmun. 2025;157:103493.
    PubMed         Abstract available


    J Diabetes Complications

  49. WISNIEWSKI A, DeMonte J, Sarteau AC, Fruik A, et al
    Levels of diabetes distress and its sources among older adults with type 1 diabetes and relationships to diabetes duration.
    J Diabetes Complications. 2025;39:109198.
    PubMed         Abstract available

  50. ABDELHAFIZ AH, Siqueira I, Sinclair AJ
    Criteria of frail older people with type 2 diabetes who are suitable for SGLT-2 inhibitors and GLP-1RA therapy.
    J Diabetes Complications. 2025;39:109193.
    PubMed         Abstract available

  51. ZUBIRIA JM, Molina E, Toledo E, Forga L, et al
    Association of matrix metalloproteinase-10 levels and genetic variant rs17860955 with severe vascular complications in patients with type 1 diabetes: prospective cohort.
    J Diabetes Complications. 2025;39:109200.
    PubMed         Abstract available


    Kidney Int

  52. NARONGKIATIKHUN P, Bjornstad P
    Unmasking the hidden burden of prediabetes on kidney function.
    Kidney Int. 2025;108:751-753.
    PubMed         Abstract available

  53. MELSOM T, Brobak KM, Norvik JV, Enoksen IT, et al
    Iohexol clearance, but not estimated GFR, reveals a steeper GFR decline in patients with prediabetes.
    Kidney Int. 2025;108:938-947.
    PubMed         Abstract available


    Metabolism

  54. PAN L, He Y, Xiang Y, Mao B, et al
    Angiopoietin-like protein 8 mediates inflammation and fibrosis of tubular cells in diabetic kidney disease progression by interacting with Akt2.
    Metabolism. 2025 Oct 17:156418. doi: 10.1016/j.metabol.2025.156418.
    PubMed         Abstract available


    Ophthalmol Retina

  55. IP M, Chaudhary V, He F, Bouillaud E, et al
    Brolucizumab for Diabetic Macular Edema in Participants With/Without Prior Anti-VEGF Exposure: KINGFISHER Study Post Hoc Analysis.
    Ophthalmol Retina. 2025 Oct 21:S2468-6530(25)00465.
    PubMed         Abstract available


    PLoS Comput Biol

  56. PATIDAR K, Ford Versypt AN
    Multi-cellular network model predicts alterations in glomerular endothelial structure in diabetic kidney disease.
    PLoS Comput Biol. 2025;21:e1013598.
    PubMed         Abstract available


    PLoS One

  57. LEHMANN A, Meslot C, Roustit M, Bardet JD, et al
    Development of a self-administered questionnaire to identify levers and barriers to adherence to medication regimens for chronic disease: The QUILAM project.
    PLoS One. 2025;20:e0323542.
    PubMed         Abstract available

  58. ZENG Y, Lu L, Zheng W, Chen G, et al
    The association between HbA1c/HDL-C and the incidence of cardiometabolic multimorbidity in middle-aged and elderly adults: Results from the China Health and Retirement Longitudinal Study.
    PLoS One. 2025;20:e0332376.
    PubMed         Abstract available

  59. CHEN K, Tang C, Li Y, Zhu D, et al
    Non-linear associations of a body shape index with diabetes among adults: A cross-sectional study.
    PLoS One. 2025;20:e0333883.
    PubMed         Abstract available

  60. GERARD E, Bugday D, Calafiore M, Baran J, et al
    Development of explicit definitions of potentially inappropriate prescriptions for antidiabetic drugs in people with type 2 diabetes: A Delphi survey and consensus meeting.
    PLoS One. 2025;20:e0334836.
    PubMed         Abstract available

  61. FRAGOZO-RAMOS MC, Schenker G, Hepprich M, Gallo-Villegas J, et al
    GIP/GLP-1RA as adjunctive to automated insulin delivery in adults with Type 1 diabetes (the AID-JUNCT trial): Study protocol for a prospective, randomized, clinical trial.
    PLoS One. 2025;20:e0335060.
    PubMed         Abstract available


  62. Editorial Note: Urinary Exosomal microRNA-451-5p Is a Potential Early Biomarker of Diabetic Nephropathy in Rats.
    PLoS One. 2025;20:e0334987.
    PubMed        

  63. TRIPATHI P, Kadam N, Kathrikolly T, Tiwari D, et al
    Type 2 diabetes remission and its predictors in an Indian cohort: A retrospective analysis of an intensive lifestyle intervention program.
    PLoS One. 2025;20:e0333114.
    PubMed         Abstract available

  64. NOMAN M, Hanif M, Hameed A, Babar M, et al
    Machine learning-driven Diabetes Health Tracer (DHT): Optimizing prognosis using RaSK_GraDe and RaSK_GraDeL models.
    PLoS One. 2025;20:e0327661.
    PubMed         Abstract available

  65. TABUE-TEGUO M, Simo N, Placide-Francil A, Drame M, et al
    Frailty and 12-month mortality among older adults with type 2 diabetes in nursing homes: A longitudinal study.
    PLoS One. 2025;20:e0332330.
    PubMed         Abstract available


    Retina

  66. LIU D, Maguire MG, Jonna G, Jampol LM, et al
    Association of Patient Age with Response to Anti-Vascular Endothelial Growth Factor Agents for Treatment of Diabetic Macular Edema.
    Retina. 2025 Oct 14. doi: 10.1097/IAE.0000000000004707.
    PubMed         Abstract available

  67. LAN T, Huang C, Tao M, Xu X, et al
    The feasibility of Ultra-widefield SS-OCTA to guide laser photocoagulation in retinal vascular diseases.
    Retina. 2025 Jun 24. doi: 10.1097/IAE.0000000000004593.
    PubMed         Abstract available


    Transplantation

  68. PEROSA M, Branez JR, Danziere FR, Zeballos B, et al
    Over 1000 Pancreas Transplants in a Latin American Program.
    Transplantation. 2025;109:e656-e665.
    PubMed         Abstract available

  69. CHAUHAN I, Llore NP, Hirakata A, Ishikawa Y, et al
    Progressive Hyperglycemia in Tolerant Miniature Swine Recipients of Composite Islet-kidney Grafts Is not due to Islet Loss but Rather to Increased Insulin Demand With Growth.
    Transplantation. 2025;109:1744-1753.
    PubMed         Abstract available


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