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Diabetes

Free Subscription Articles published in Proc Natl Acad Sci U S A Retrieve available abstracts of 62 articles: HTML format

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November 2024
1. MOURAD NI, Perota A, Xhema D, Duchi R, et al
   Double transgenic neonatal porcine islets as an alternative source for beta cell replacement therapy.
   Proc Natl Acad Sci U S A. 2024;121:e2409138121.
   PubMed     Abstract available
   
   
   October 2024
2. PATHAK V, Bertelli PM, Pedrini E, Harkin K, et al
   Modulation of diabetes-related retinal pathophysiology by PTX3.
   Proc Natl Acad Sci U S A. 2024;121:e2320034121.
   PubMed     Abstract available
   
   
   September 2024
3. HAN B, Hu J, Yang C, Tang J, et al
   Lactobacillus Firm-5-derived succinate prevents honeybees from having diabetes-like symptoms.
   Proc Natl Acad Sci U S A. 2024;121:e2405410121.
   PubMed     Abstract available
   
   
   August 2024
4. DU W, Jiang S, Yin S, Wang R, et al
   The microbiota-dependent tryptophan metabolite alleviates high-fat diet-induced insulin resistance through the hepatic AhR/TSC2/mTORC1 axis.
   Proc Natl Acad Sci U S A. 2024;121:e2400385121.
   PubMed     Abstract available
   
   
   
5. KITAMURA RA, Hummel D, Ustione A, Piston DW, et al
   Dual role of neuroplastin in pancreatic beta cells: Regulating insulin secretion and promoting islet inflammation.
   Proc Natl Acad Sci U S A. 2024;121:e2411234121.
   PubMed     Abstract available
   
   
   June 2024
6. SULADZE S, Sarkar R, Rodina N, Bokvist K, et al
   Atomic resolution structure of full-length human insulin fibrils.
   Proc Natl Acad Sci U S A. 2024;121:e2401458121.
   PubMed     Abstract available
   
   
   May 2024
7. WANG S, Zhang Y, Zhong Y, Xue Y, et al
   Accelerating diabetic wound healing by ROS-scavenging lipid nanoparticle-mRNA formulation.
   Proc Natl Acad Sci U S A. 2024;121:e2322935121.
   PubMed     Abstract available
   
   
   April 2024
8. WOO JR, Bae SH, Wales TE, Engen JR, et al
   The serine phosphorylations in the IRS-1 PIR domain abrogate IRS-1 and IR interaction.
   Proc Natl Acad Sci U S A. 2024;121:e2401716121.
   PubMed     Abstract available
   
   
   
9. SHAO S, Zhang N, Specht GP, You S, et al
   Pharmacological expansion of type 2 alveolar epithelial cells promotes regenerative lower airway repair.
   Proc Natl Acad Sci U S A. 2024;121:e2400077121.
   PubMed     Abstract available
   
   
   March 2024
10. TASSOULAS LJ, Rankin JA, Elias MH, Wackett LP, et al
    Dinickel enzyme evolved to metabolize the pharmaceutical metformin and its implications for wastewater and human microbiomes.
    Proc Natl Acad Sci U S A. 2024;121:e2312652121.
    PubMed     Abstract available
    
    
    February 2024
11. KULAK K, Kuska K, Colineau L, Mckay M, et al
    Intracellular C3 protects beta-cells from IL-1beta-driven cytotoxicity via interaction with Fyn-related kinase.
    Proc Natl Acad Sci U S A. 2024;121:e2312621121.
    PubMed     Abstract available
    
    
    
12. SELCK C, Jhala G, De George DJ, Kwong CJ, et al
    Extraislet expression of islet antigen boosts T cell exhaustion to partially prevent autoimmune diabetes.
    Proc Natl Acad Sci U S A. 2024;121:e2315419121.
    PubMed     Abstract available
    
    
    January 2024
13. LI Q, Tangry V, Allen DP, Seibert KD, et al
    Surface-mediated spontaneous emulsification of the acylated peptide, semaglutide.
    Proc Natl Acad Sci U S A. 2024;121:e2305770121.
    PubMed     Abstract available
    
    
    December 2023
14. DUTTA DJ, Sasaki J, Bansal A, Sugai K, et al
    Alternative splicing events as peripheral biomarkers for motor learning deficit caused by adverse prenatal environments.
    Proc Natl Acad Sci U S A. 2023;120:e2304074120.
    PubMed     Abstract available
    
    
    
15. YE C, Clements SA, Gu W, Geurts AM, et al
    Deletion of Vbeta3(+)CD4(+) T cells by endogenous mouse mammary tumor virus 3 prevents type 1 diabetes induction by autoreactive CD8(+) T cells.
    Proc Natl Acad Sci U S A. 2023;120:e2312039120.
    PubMed     Abstract available
    
    
    November 2023
16. ZHONG X, Moresco JJ, Keller K, Lazaro DR, et al
    Essential requirement for IER3IP1 in B cell development.
    Proc Natl Acad Sci U S A. 2023;120:e2312810120.
    PubMed     Abstract available
    
    
    
17. PFEIFER CW, Walsh JT, Santeford A, Lin JB, et al
    Dysregulated CD200-CD200R signaling in early diabetes modulates microglia-mediated retinopathy.
    Proc Natl Acad Sci U S A. 2023;120:e2308214120.
    PubMed     Abstract available
    
    
    September 2023
18. GAN T, Wang D
    Picobirnaviruses encode proteins that are functional bacterial lysins.
    Proc Natl Acad Sci U S A. 2023;120:e2309647120.
    PubMed     Abstract available
    
    
    August 2023
19. HUDAIBERDIEV S, Taylor DL, Song W, Narisu N, et al
    Modeling islet enhancers using deep learning identifies candidate causal variants at loci associated with T2D and glycemic traits.
    Proc Natl Acad Sci U S A. 2023;120:e2206612120.
    PubMed     Abstract available
    
    
    
20. EISENBEIS VB, Qiu D, Gorka O, Strotmann L, et al
    beta-lapachone regulates mammalian inositol pyrophosphate levels in an NQO1- and oxygen-dependent manner.
    Proc Natl Acad Sci U S A. 2023;120:e2306868120.
    PubMed     Abstract available
    
    
    
21. ADAM RC, Pryce DS, Lee JS, Zhao Y, et al
    Activin E-ACVR1C cross talk controls energy storage via suppression of adipose lipolysis in mice.
    Proc Natl Acad Sci U S A. 2023;120:e2309967120.
    PubMed     Abstract available
    
    
    
22. HIRAIKE Y, Saito K, Oguchi M, Wada T, et al
    NFIA in adipocytes reciprocally regulates mitochondrial and inflammatory gene program to improve glucose homeostasis.
    Proc Natl Acad Sci U S A. 2023;120:e2308750120.
    PubMed     Abstract available
    
    
    July 2023
23. 
    Correction to Supporting Information for Girdhar et al., A gut microbial peptide and molecular mimicry in the pathogenesis of type 1 diabetes.
    Proc Natl Acad Sci U S A. 2023;120:e2309963120.
    PubMed    
    
    
    
24. MOLLER LLV, Ali MS, Davey J, Raun SH, et al
    The Rho guanine dissociation inhibitor alpha inhibits skeletal muscle Rac1 activity and insulin action.
    Proc Natl Acad Sci U S A. 2023;120:e2211041120.
    PubMed     Abstract available
    
    
    June 2023
25. LOUZADA RA, Blandino-Rosano M, Flores S, Lubaczeuski C, et al
    GRHR agonist MR-409 protects beta-cells from streptozotocin-induced diabetes.
    Proc Natl Acad Sci U S A. 2023;120:e2209810120.
    PubMed     Abstract available
    
    
    
26. XUE Y, Cui A, Wei S, Ma F, et al
    Proline hydroxylation of CREB-regulated transcriptional coactivator 2 controls hepatic glucose metabolism.
    Proc Natl Acad Sci U S A. 2023;120:e2219419120.
    PubMed     Abstract available
    
    
    May 2023
27. CHEN W, Huang Q, Lazdon EK, Gomes A, et al
    Loss of insulin signaling in astrocytes exacerbates Alzheimer-like phenotypes in a 5xFAD mouse model.
    Proc Natl Acad Sci U S A. 2023;120:e2220684120.
    PubMed     Abstract available
    
    
    
28. C LUU J, Saadane A, Leinonen H, H Choi E, et al
    Stress resilience-enhancing drugs preserve tissue structure and function in degenerating retina via phosphodiesterase inhibition.
    Proc Natl Acad Sci U S A. 2023;120:e2221045120.
    PubMed     Abstract available
    
    
    
29. WANG A, Jing Y, Cheng Q, Zhou H, et al
    Loss of function of SSIIIa and SSIIIb coordinately confers high RS content in cooked rice.
    Proc Natl Acad Sci U S A. 2023;120:e2220622120.
    PubMed     Abstract available
    
    
    April 2023
30. SONG Y, Bell DR, Ahmed R, Chan KC, et al
    A mutagenesis study of autoantigen optimization for potential T1D vaccine design.
    Proc Natl Acad Sci U S A. 2023;120:e2214430120.
    PubMed     Abstract available
    
    
    
31. POZO M, Mila-Guasch M, Haddad-Tovolli R, Boudjadja MB, et al
    Negative energy balance hinders prosocial helping behavior.
    Proc Natl Acad Sci U S A. 2023;120:e2218142120.
    PubMed     Abstract available
    
    
    March 2023
32. LIANG W, Huang L, Whelchel A, Yuan T, et al
    Peroxisome proliferator-activated receptor-alpha (PPARalpha) regulates wound healing and mitochondrial metabolism in the cornea.
    Proc Natl Acad Sci U S A. 2023;120:e2217576120.
    PubMed     Abstract available
    
    
    
33. FERRIS ST, Liu T, Chen J, Ohara RA, et al
    WDFY4 deficiency in NOD mice ameliorates autoimmune diabetes and insulitis.
    Proc Natl Acad Sci U S A. 2023;120:e2219956120.
    PubMed     Abstract available
    
    
    
34. 
    Correction for Taylor et al., Human pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysis.
    Proc Natl Acad Sci U S A. 2023;120:e2302726120.
    PubMed    
    
    
    February 2023
35. TAYLOR HJ, Hung YH, Narisu N, Erdos MR, et al
    Human pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysis.
    Proc Natl Acad Sci U S A. 2023;120:e2206797120.
    PubMed     Abstract available
    
    
    January 2023
36. TOBAR N, Rocha GZ, Santos A, Guadagnini D, et al
    Metformin acts in the gut and induces gut-liver crosstalk.
    Proc Natl Acad Sci U S A. 2023;120:e2211933120.
    PubMed     Abstract available
    
    
    
37. SONG W, Postoak JL, Yang G, Guo X, et al
    Lipid kinase PIK3C3 maintains healthy brown and white adipose tissues to prevent metabolic diseases.
    Proc Natl Acad Sci U S A. 2023;120:e2214874120.
    PubMed     Abstract available
    
    
    
38. MEDA VENKATA SP, Li H, Xu L, Koh JY, et al
    Inhibition of GPR39 restores defects in endothelial cell-mediated neovascularization under the duress of chronic hyperglycemia: Evidence for regulatory roles of the sonic hedgehog signaling axis.
    Proc Natl Acad Sci U S A. 2023;120:e2208541120.
    PubMed     Abstract available
    
    
    December 2022
39. NEMETCHEK MD, Chrisman IM, Rayl ML, Voss AH, et al
    A structural mechanism of nuclear receptor biased agonism.
    Proc Natl Acad Sci U S A. 2022;119:e2215333119.
    PubMed     Abstract available
    
    
    
40. LEE HY, Jang HR, Li H, Samuel VT, et al
    Deletion of Jazf1 gene causes early growth retardation and insulin resistance in mice.
    Proc Natl Acad Sci U S A. 2022;119:e2213628119.
    PubMed     Abstract available
    
    
    November 2022
41. RUBIN DE CELIS MF, Garcia-Martin R, Syed I, Lee J, et al
    PAHSAs reduce cellular senescence and protect pancreatic beta cells from metabolic stress through regulation of Mdm2/p53.
    Proc Natl Acad Sci U S A. 2022;119:e2206923119.
    PubMed     Abstract available
    
    
    
42. YANG J, Zhen J, Feng W, Fan Z, et al
    IER3IP1 is critical for maintaining glucose homeostasis through regulating the endoplasmic reticulum function and survival of beta cells.
    Proc Natl Acad Sci U S A. 2022;119:e2204443119.
    PubMed     Abstract available
    
    
    October 2022
43. NIES VJM, Struik D, Liu S, Liu W, et al
    Autocrine FGF1 signaling promotes glucose uptake in adipocytes.
    Proc Natl Acad Sci U S A. 2022;119:e2122382119.
    PubMed     Abstract available
    
    
    
44. DU Q, Wu J, Fischer C, Seki T, et al
    Generation of mega brown adipose tissue in adults by controlling brown adipocyte differentiation in vivo.
    Proc Natl Acad Sci U S A. 2022;119:e2203307119.
    PubMed     Abstract available
    
    
    August 2022
45. GIRDHAR K, Huang Q, Chow IT, Vatanen T, et al
    A gut microbial peptide and molecular mimicry in the pathogenesis of type 1 diabetes.
    Proc Natl Acad Sci U S A. 2022;119:e2120028119.
    PubMed     Abstract available
    
    
    June 2022
46. GOLEC E, Ekstrom A, Noga M, Omar-Hmeadi M, et al
    Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets.
    Proc Natl Acad Sci U S A. 2022;119:e2120083119.
    PubMed     Abstract available
    
    
    April 2022
47. BELAVGENI A, Maremonti F, Stadtmuller M, Bornstein SR, et al
    Schwann cell necroptosis in diabetic neuropathy.
    Proc Natl Acad Sci U S A. 2022;119:e2204049119.
    PubMed    
    
    
    
48. POSTIGO-FERNANDEZ J, Firdessa-Fite R, Creusot RJ
    Preclinical evaluation of a precision medicine approach to DNA vaccination in type 1 diabetes.
    Proc Natl Acad Sci U S A. 2022;119:e2110987119.
    PubMed     Abstract available
    
    
    
49. GUO J, Guo Z, Huang Y, Ma S, et al
    Blockage of MLKL prevents myelin damage in experimental diabetic neuropathy.
    Proc Natl Acad Sci U S A. 2022;119:e2121552119.
    PubMed     Abstract available
    
    
    
50. MADRIGAL-MATUTE J, de Bruijn J, van Kuijk K, Riascos-Bernal DF, et al
    Protective role of chaperone-mediated autophagy against atherosclerosis.
    Proc Natl Acad Sci U S A. 2022;119:e2121133119.
    PubMed     Abstract available
    
    
    March 2022
51. SUN B, Willard FS, Feng D, Alsina-Fernandez J, et al
    Structural determinants of dual incretin receptor agonism by tirzepatide.
    Proc Natl Acad Sci U S A. 2022;119:e2116506119.
    PubMed     Abstract available
    
    
    
52. SHIGEMORI K, Nomura S, Umeda T, Takeda S, et al
    Peripheral Abeta acts as a negative modulator of insulin secretion.
    Proc Natl Acad Sci U S A. 2022;119:e2117723119.
    PubMed     Abstract available
    
    
    
53. ZHENG X, Ho QWC, Chua M, Stelmashenko O, et al
    Destabilization of beta Cell FIT2 by saturated fatty acids alter lipid droplet numbers and contribute to ER stress and diabetes.
    Proc Natl Acad Sci U S A. 2022;119:e2113074119.
    PubMed     Abstract available
    
    
    February 2022
54. QIAO J, Zhang Z, Ji S, Liu T, et al
    A distinct role of STING in regulating glucose homeostasis through insulin sensitivity and insulin secretion.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available
    
    
    December 2021
55. MILLS SA, Jobling AI, Dixon MA, Bui BV, et al
    Fractalkine-induced microglial vasoregulation occurs within the retina and is altered early in diabetic retinopathy.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    November 2021
56. FORAY AP, Candon S, Hildebrand S, Marquet C, et al
    De novo germline mutation in the dual specificity phosphatase 10 gene accelerates autoimmune diabetes.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    
57. YAHIL S, Wozniak DF, Yan Z, Mennerick S, et al
    Cognitive deficits and impaired hippocampal long-term potentiation in KATP-induced DEND syndrome.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    
58. VON HERRATH M, Bonifacio E
    How benign autoimmunity becomes detrimental in type 1 diabetes.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    
    
    
    October 2021
59. ANDERSON AM, Landry LG, Alkanani AA, Pyle L, et al
    Human islet T cells are highly reactive to preproinsulin in type 1 diabetes.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    
60. RAMIREZ DG, Ciccaglione M, Upadhyay AK, Pham VT, et al
    Detecting insulitis in type 1 diabetes with ultrasound phase-change contrast agents.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    September 2021
61. YANG K, O'Cearbhaill ED, Liu SS, Zhou A, et al
    A therapeutic convection-enhanced macroencapsulation device for enhancing beta cell viability and insulin secretion.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    March 2021
62. CAI S, Li H, Zheng F, Kong F, et al
    Artificial intelligence velocimetry and microaneurysm-on-a-chip for three-dimensional analysis of blood flow in physiology and disease.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    

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