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Articles published in J Clin Invest

Retrieve available abstracts of 38 articles:
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Single Articles


    July 2020
  1. DEHNAD A, Fan W, Jiang JX, Fish SR, et al
    AGER1 downregulation associates with fibrosis in nonalcoholic steatohepatitis and type 2 diabetes.
    J Clin Invest. 2020 Jul 13. pii: 133051. doi: 10.1172/JCI133051.
    PubMed     Abstract available


    June 2020
  2. OTTO M, Bucher C, Liu W, Muller M, et al
    12(S)-HETE mediates diabetes induced endothelial dysfunction by activating intracellular endothelial cell TRPV1.
    J Clin Invest. 2020 Jun 25. pii: 136621. doi: 10.1172/JCI136621.
    PubMed     Abstract available


    May 2020
  3. MEAKIN PJ, Coull BM, Tuharska Z, McCaffery C, et al
    Elevated circulating amyloid concentrations in obesity and diabetes promote vascular dysfunction.
    J Clin Invest. 2020 May 14. pii: 122237. doi: 10.1172/JCI122237.
    PubMed     Abstract available


  4. LIU Y, Lin H, Jiang L, Shang Q, et al
    Hepatic Slug epigenetically promotes liver lipogenesis, fatty liver disease, and type 2 diabetes.
    J Clin Invest. 2020 May 4. pii: 128073. doi: 10.1172/JCI128073.
    PubMed     Abstract available


    April 2020
  5. JIANG Q, Liu C, Li C, Xu S, et al
    Circular RNA-ZNF532 regulates diabetes-induced retinal pericyte degeneration and vascular dysfunction.
    J Clin Invest. 2020 Apr 28. pii: 123353. doi: 10.1172/JCI123353.
    PubMed     Abstract available


    January 2020
  6. RICKELS MR, Evans-Molina C, Bahnson HT, Ylescupidez A, et al
    High residual C-peptide likely contributes to glycemic control in type 1 diabetes.
    J Clin Invest. 2020 Jan 2. pii: 134057. doi: 10.1172/JCI134057.
    PubMed     Abstract available


    December 2019
  7. WIEDEMAN AE, Muir VS, Rosasco MG, DeBerg HA, et al
    Autoreactive CD8+ T cell exhaustion distinguishes subjects with slow type 1 diabetes progression.
    J Clin Invest. 2019 Dec 9. pii: 126595. doi: 10.1172/JCI126595.
    PubMed     Abstract available


  8. ELLARD S, Colclough K, Patel KA, Hattersley AT, et al
    Prediction algorithms: pitfalls in interpreting genetic variants of autosomal dominant monogenic diabetes.
    J Clin Invest. 2019 Dec 9. pii: 133516. doi: 10.1172/JCI133516.
    PubMed    


    October 2019
  9. LAM AN, Aksit MA, Vecchio-Pagan B, Shelton CA, et al
    Increased expression of anion transporter SLC26A9 delays diabetes onset in cystic fibrosis.
    J Clin Invest. 2019 Oct 3. pii: 129833. doi: 10.1172/JCI129833.
    PubMed     Abstract available


    September 2019
  10. MEYER MM
    Trials and tribulations of diabetes: a patient's perspective.
    J Clin Invest. 2019 Sep 23. pii: 132144. doi: 10.1172/JCI132144.
    PubMed    


  11. SODHI A, Ma T, Menon D, Deshpande M, et al
    Angiopoietin-like 4 binds neuropilins and cooperates with VEGF to induce diabetic macular edema.
    J Clin Invest. 2019 Sep 23. pii: 120879. doi: 10.1172/JCI120879.
    PubMed     Abstract available


    August 2019
  12. GINSBERG HN, Reyes-Soffer G
    Is APOC3 the driver of cardiovascular disease in people with type I diabetes mellitus?
    J Clin Invest. 2019 Aug 26. pii: 131333. doi: 10.1172/JCI131333.
    PubMed     Abstract available


  13. HUDISH LI, Reusch JE, Sussel L
    beta Cell dysfunction during progression of metabolic syndrome to type 2 diabetes.
    J Clin Invest. 2019 Aug 19. pii: 129188. doi: 10.1172/JCI129188.
    PubMed     Abstract available


  14. HAMAD ARA, Sadasivam M, Rabb H
    Hybrid lipids, peptides, and lymphocytes: new era in type 1 diabetes research.
    J Clin Invest. 2019;130.
    PubMed     Abstract available


  15. SYED I, Rubin de Celis MF, Mohan JF, Moraes-Vieira PM, et al
    PAHSAs attenuate immune responses and promote beta cell survival in autoimmune diabetic mice.
    J Clin Invest. 2019;129.
    PubMed     Abstract available


  16. MOORE PC, Cortez JT, Chamberlain CE, Alba D, et al
    Elastase 3B mutation links to familial pancreatitis with diabetes and pancreatic adenocarcinoma.
    J Clin Invest. 2019;130.
    PubMed     Abstract available


    July 2019
  17. KELLER MP, Rabaglia ME, Schueler KL, Stapleton DS, et al
    Gene loci associated with insulin secretion in islets from non-diabetic mice.
    J Clin Invest. 2019;130.
    PubMed     Abstract available


  18. BROWN JM, Scarlett JM, Schwartz MW
    Rethinking the role of the brain in glucose homeostasis and diabetes pathogenesis.
    J Clin Invest. 2019;130.
    PubMed    


  19. KANTER JE, Shao B, Kramer F, Barnhart S, et al
    Increased apolipoprotein C3 drives cardiovascular risk in type 1 diabetes.
    J Clin Invest. 2019;130.
    PubMed     Abstract available


  20. JAAFAR R, Tran S, Shah A, Sun G, et al
    mTORC1 to AMPK switching underlies beta-cell metabolic plasticity during maturation and diabetes.
    J Clin Invest. 2019;130.
    PubMed     Abstract available


  21. YU MG, Keenan HA, Shah HS, Frodsham SG, et al
    Residual beta cell function and monogenic variants in long-duration type 1 diabetes patients.
    J Clin Invest. 2019;130.
    PubMed     Abstract available


    June 2019
  22. SYED AU, Reddy GR, Ghosh D, Prada MP, et al
    Adenylyl cyclase 5-generated cAMP controls cerebral vascular reactivity during diabetic hyperglycemia.
    J Clin Invest. 2019;130.
    PubMed     Abstract available


    May 2019
  23. GALVAN DL, Long J, Green N, Chang BH, et al
    Drp1S600 phosphorylation regulates mitochondrial fission and progression of nephropathy in diabetic mice.
    J Clin Invest. 2019;130.
    PubMed     Abstract available


    April 2019
  24. COHEN TS, Takahashi V, Bonnell J, Tovchigrechko A, et al
    Staphylococcus aureus drives expansion of low-density neutrophils in diabetic mice.
    J Clin Invest. 2019;130.
    PubMed     Abstract available


    February 2019
  25. LI Y, Hu Q, Li C, Liang K, et al
    PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease.
    J Clin Invest. 2019 Feb 11. pii: 121987. doi: 10.1172/JCI121987.
    PubMed     Abstract available


    January 2019
  26. GUERRA C, Navarro P, Valverde AM, Arribas M, et al
    Brown adipose tissue-specific insulin receptor knockout shows diabetic phenotype without insulin resistance.
    J Clin Invest. 2019;129:437.
    PubMed    


    November 2018
  27. ZASLOFF M
    Why are diabetics prone to kidney infections?
    J Clin Invest. 2018 Nov 12. pii: 124922. doi: 10.1172/JCI124922.
    PubMed     Abstract available


    August 2018
  28. WU H, Rahman HNA, Dong Y, Liu X, et al
    Epsin deficiency promotes lymphangiogenesis through regulation of VEGFR3 degradation in diabetes.
    J Clin Invest. 2018 Aug 13. pii: 96063. doi: 10.1172/JCI96063.
    PubMed     Abstract available


    July 2018
  29. HSU CY, Yeh LT, Fu SH, Chien MW, et al
    SUMO-defective c-Maf preferentially transactivates Il21 to exacerbate autoimmune diabetes.
    J Clin Invest. 2018 Jul 30. pii: 98786. doi: 10.1172/JCI98786.
    PubMed     Abstract available


    May 2018
  30. YEO L, Woodwyk A, Sood S, Lorenc A, et al
    Autoreactive T effector memory differentiation mirrors beta-cell function in type 1 diabetes.
    J Clin Invest. 2018 May 31. pii: 120555. doi: 10.1172/JCI120555.
    PubMed     Abstract available


    March 2018
  31. JAYARAJ ND, Bhattacharyya BJ, Belmadani AA, Ren D, et al
    Reducing CXCR4-mediated nociceptor hyperexcitability reverses painful diabetic neuropathy.
    J Clin Invest. 2018 Mar 13. pii: 92117. doi: 10.1172/JCI92117.
    PubMed     Abstract available


    February 2018
  32. OSTROV DA, Alkanani A, McDaniel KA, Case S, et al
    Methyldopa blocks MHC class II binding to disease-specific antigens in autoimmune diabetes.
    J Clin Invest. 2018 Feb 13. pii: 97739. doi: 10.1172/JCI97739.
    PubMed     Abstract available


  33. TAYLOR SI, Leslie BR
    Cardiovascular outcome trials of diabetes drugs: lessons learned.
    J Clin Invest. 2018 Feb 12. pii: 99820. doi: 10.1172/JCI99820.
    PubMed    


    January 2018
  34. HWANG JJ, Parikh L, Lacadie C, Seo D, et al
    Hypoglycemia unawareness in type 1 diabetes suppresses brain responses to hypoglycemia.
    J Clin Invest. 2018 Jan 30. pii: 97696. doi: 10.1172/JCI97696.
    PubMed     Abstract available


    December 2017
  35. DRUCKER DJ, Habener JF, Holst JJ
    Discovery, characterization, and clinical development of the glucagon-like peptides.
    J Clin Invest. 2017;127:4217-4227.
    PubMed     Abstract available


    October 2017
  36. O'SULLIVAN JF, Morningstar JE, Yang Q, Zheng B, et al
    Dimethylguanidino valeric acid is a marker of liver fat and predicts diabetes.
    J Clin Invest. 2017 Oct 30. pii: 95995. doi: 10.1172/JCI95995.
    PubMed     Abstract available


  37. ZHU W, Shi DS, Winter JM, Rich BE, et al
    Small GTPase ARF6 controls VEGFR2 trafficking and signaling in diabetic retinopathy.
    J Clin Invest. 2017 Oct 23. pii: 91770. doi: 10.1172/JCI91770.
    PubMed     Abstract available


    September 2017
  38. BICHET DG, Lussier Y
    Mice deficient for ERAD machinery component Sel1L develop central diabetes insipidus.
    J Clin Invest. 2017 Sep 18. pii: 96839. doi: 10.1172/JCI96839.
    PubMed     Abstract available


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