Home The Word Brain My Amedeo FAQ Privacy About   


Explore this week’s CC Journal Club

90‑sec video • 4‑min audio • paper abstracts

This week, 27 April 2025:

  1. Treatment-resistant hypertension
  2. Influenza transmission
  3. Nanoplastics in human brains
  4. Malaria elimination
  5. Chikungunya vaccine

  Drug Resistance

  Free Subscription


Articles published in Antimicrob Agents Chemother

Retrieve available abstracts of 170 articles:
HTML format



Single Articles


    April 2025
  1. LEE J, Lee I, Lee K-B, Lee SS, et al
    Comparative effectiveness and safety of colistin-based versus high-dose ampicillin/sulbactam-based combination therapy for nosocomial pneumonia caused by carbapenem-resistant Acinetobacter baumannii.
    Antimicrob Agents Chemother. 2025 Apr 23:e0188024. doi: 10.1128/aac.01880.
    PubMed     Abstract available


  2. ZHANG Y, Zhou B, Kong J, Hu P, et al
    Prevalence and characteristics of tigecycline- and carbapenem-resistant adeN-truncated Acinetobacter baumannii: a genomic epidemiological analysis.
    Antimicrob Agents Chemother. 2025 Apr 23:e0184324. doi: 10.1128/aac.01843.
    PubMed     Abstract available


  3. SZEL V, Phelan JE, Georghiou SB, Dolinger DL, et al
    The ahpC c-54t compensatory mutation is not always a valid surrogate for isoniazid resistance in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2025 Apr 22:e0026525. doi: 10.1128/aac.00265.
    PubMed     Abstract available


  4. SHERRY NL, Lee JYH, Giulieri SG, Connor CH, et al
    Genomics for antimicrobial resistance-progress and future directions.
    Antimicrob Agents Chemother. 2025 Apr 14:e0108224. doi: 10.1128/aac.01082.
    PubMed     Abstract available


  5. SASTRE-FEMENIA MA, Gomis-Font MA, Oliver A
    Mutant prevention concentrations and phenotypic and genomic profiling of first-step resistance mechanisms to classical and novel beta-lactams in Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2025;69:e0194224.
    PubMed     Abstract available


  6. SADER HS, Castanheira M, Arends SJR, Doyle TB, et al
    Antimicrobial susceptibility of Stenotrophomonas maltophilia from United States medical centers (2019-2023).
    Antimicrob Agents Chemother. 2025;69:e0012425.
    PubMed     Abstract available


  7. SAMPER-CATIVIELA C, Torre-Fuentes L, Dieguez-Roda B, Maex M, et al
    Molecular epidemiology of Salmonella Enteritidis in humans and animals in Spain.
    Antimicrob Agents Chemother. 2025;69:e0073824.
    PubMed     Abstract available


  8. MA Y, Pirolo M, Giarratana L, Leth Nielsen K, et al
    Chromosomal genes modulating fosfomycin susceptibility in uropathogenic Escherichia coli: a genome-wide analysis.
    Antimicrob Agents Chemother. 2025;69:e0141724.
    PubMed     Abstract available


  9. PROENCA AM, Rang CU, Chao L
    A link between aging and persistence.
    Antimicrob Agents Chemother. 2025;69:e0131324.
    PubMed     Abstract available


  10. HUSSAIN A, Bhando T, Casius A, Gupta R, et al
    Deciphering meropenem persistence in Acinetobacter baumannii facilitates discovery of anti-persister activity of thymol.
    Antimicrob Agents Chemother. 2025;69:e0138124.
    PubMed     Abstract available


    March 2025
  11. SONG Y, An Q, Chen S, Dai H, et al
    Antimicrobial resistance of pet-derived bacteria in China, 2000-2020.
    Antimicrob Agents Chemother. 2025 Mar 26:e0165724. doi: 10.1128/aac.01657.
    PubMed     Abstract available


  12. MAHE A, Verneuil N, Coupri D, Hartke A, et al
    D-alanylation of lipoteichoic acids inhibitor provides anti-virulence and anti-resistance effects against methicillin-resistant Staphylococcus epidermidis.
    Antimicrob Agents Chemother. 2025 Mar 21:e0182224. doi: 10.1128/aac.01822.
    PubMed     Abstract available


  13. MUNITA JM, Tamma PD
    Fighting resistance with redundancy: a path forward for treating antimicrobial-resistant infections?
    Antimicrob Agents Chemother. 2025 Mar 14:e0012125. doi: 10.1128/aac.00121.
    PubMed     Abstract available


  14. PETERSEN ME, Khamas AB, Ostergaard LJ, Jorgensen NP, et al
    Combination therapy delays antimicrobial resistance after adaptive laboratory evolution of Staphylococcus aureus.
    Antimicrob Agents Chemother. 2025 Mar 14:e0148324. doi: 10.1128/aac.01483.
    PubMed     Abstract available


  15. ZHAO L, Li C, Wang M, Zhou M, et al
    Potent antiviral activity of simnotrelvir against key epidemic SARS-CoV-2 variants with a high resistance barrier.
    Antimicrob Agents Chemother. 2025 Mar 10:e0155624. doi: 10.1128/aac.01556.
    PubMed     Abstract available


  16. YU Z, Hu H, Liu X, Liu J, et al
    Clinical outcomes and pharmacokinetics/pharmacodynamics of intravenous polymyxin B treatment for various site carbapenem-resistant gram-negative bacterial infections: a prospective observational multicenter study.
    Antimicrob Agents Chemother. 2025 Mar 6:e0185924. doi: 10.1128/aac.01859.
    PubMed     Abstract available


  17. LEMAITRE N, Dewitte A, Rakotomanimana F, Gooden D, et al
    Assessing the threat of Yersinia pestis harboring a multi-resistant IncC plasmid and the efficacy of an antibiotic targeting LpxC.
    Antimicrob Agents Chemother. 2025;69:e0149724.
    PubMed     Abstract available


  18. ROJAS LJ, Nielsen TB, Pantapalangkoor P, Taracila MA, et al
    Restoring cefepime activity against multidrug-resistant KPC-producing Klebsiella pneumoniae by combination with boronic acid inhibitors, MB076 and S02030.
    Antimicrob Agents Chemother. 2025;69:e0096424.
    PubMed     Abstract available


  19. DORAZIO AJ, Kline EG, Squires KM, Pogue JM, et al
    Restoring ceftolozane susceptibility: a role for diazabicyclooctane beta-lactamase inhibitors?
    Antimicrob Agents Chemother. 2025;69:e0154324.
    PubMed     Abstract available


  20. CORNISTEIN W, Balasini C, Nuccetelli Y, Rodriguez VM, et al
    Prevalence and mortality associated with multidrug-resistant infections in adult intensive care units in Argentina (PREV-AR).
    Antimicrob Agents Chemother. 2025;69:e0142624.
    PubMed     Abstract available


    February 2025
  21. YU H, Wang L, Liu X, Zheng J, et al
    Mechanistic insights into the multitarget synergistic efficacy of farrerol and beta-lactam antibiotics in combating methicillin-resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 2025 Feb 28:e0155124. doi: 10.1128/aac.01551.
    PubMed     Abstract available


  22. FU S-Y, Chen X-Z, Yi P-C, Gao J, et al
    Optimizing phage therapy for carbapenem-resistant Enterobacter cloacae bacteremia: insights into dose and timing.
    Antimicrob Agents Chemother. 2025 Feb 26:e0168324. doi: 10.1128/aac.01683.
    PubMed     Abstract available


  23. FILE TM JR, Ramirez JA, Wilde AM
    New Perspectives on Antimicrobial Agents: Omadacycline for community-acquired pneumonia, skin and soft tissue infections, and nontuberculous mycobacteria (focus on M. abscessus).
    Antimicrob Agents Chemother. 2025;69:e0108724.
    PubMed     Abstract available


  24. BONCOMPAGNI SR, Riccobono E, Cusi MG, Di Pilato V, et al
    Evidence of dissemination of a clc-type integrative and conjugative element to Stenotrophomonas maltophilia, mediating acquisition of sul1 and other resistance determinants.
    Antimicrob Agents Chemother. 2025;69:e0155424.
    PubMed     Abstract available


  25. ROSON-CALERO N, Gomis Font MA, Ruiz-Soriano A, Just-Baringo X, et al
    In vitro potentiation of tetracyclines in Pseudomonas aeruginosa by RW01, a new cyclic peptide.
    Antimicrob Agents Chemother. 2025;69:e0145924.
    PubMed     Abstract available


  26. RODRIGUEZ L, Lee HW, Li J, Martin R, et al
    SARS-CoV-2 resistance analyses from the Phase 3 PINETREE study of remdesivir treatment in nonhospitalized participants.
    Antimicrob Agents Chemother. 2025;69:e0123824.
    PubMed     Abstract available


  27. GHEBREKRISTOS Y, Ahmed A, Beylis N, Singh S, et al
    Xpert MTB/RIF Ultra-resistant and MTBDRplus-susceptible rifampicin results in people with tuberculosis: utility of FluoroType MTBDR and deep sequencing.
    Antimicrob Agents Chemother. 2025 Feb 7:e0167124. doi: 10.1128/aac.01671.
    PubMed     Abstract available


    January 2025
  28. FORRISTER NM, McCarty TP, Pappas PG
    New Perspectives on Antimicrobial Agents: Rezafungin.
    Antimicrob Agents Chemother. 2025;69:e0064623.
    PubMed     Abstract available


  29. LI T, Zhu Y, Xiang G, Xu Z, et al
    Adaptive evolution of extensive drug resistance and persistence in epidemic ST11 KPC-producing Klebsiella pneumoniae during antimicrobial chemotherapy.
    Antimicrob Agents Chemother. 2025;69:e0123524.
    PubMed     Abstract available


  30. KOENIG C, Monogue ML, Shields RK, Sakon CM, et al
    Cefiderocol pharmacokinetics during acute pulmonary exacerbations in hospitalized adult persons with cystic fibrosis.
    Antimicrob Agents Chemother. 2025;69:e0153924.
    PubMed     Abstract available


  31. HE Z, Huang Y, Li W, Zhang H, et al
    Characterization and genomic analysis of the highly virulent Acinetobacter baumannii ST1791 strain dominating in Anhui, China.
    Antimicrob Agents Chemother. 2025;69:e0126224.
    PubMed     Abstract available


  32. MORITA D, Mukhopadhyay AK, Chowdhury G, Maruyama F, et al
    Genomic epidemiology and genetic characteristics of clinical Campylobacter species cocirculating in West Bengal, India, 2019, using whole genome analysis.
    Antimicrob Agents Chemother. 2025;69:e0110824.
    PubMed     Abstract available


  33. WANG J, Liu X, Song Y, Liu Z, et al
    LC-AMP-I1, a novel venom-derived antimicrobial peptide from the wolf spider Lycosa coelestis.
    Antimicrob Agents Chemother. 2025;69:e0042424.
    PubMed     Abstract available


  34. WIEDERHOLD NP, Patterson HP, Ferrer D, Garcia V, et al
    Olorofim demonstrates in vitro activity against Coccidioides species, including isolates against which fluconazole has reduced activity.
    Antimicrob Agents Chemother. 2025;69:e0098824.
    PubMed     Abstract available


  35. ZHU Q, Wijnants S, Feil R, Van Genechten W, et al
    The stress-protectant molecule trehalose mediates fluconazole tolerance in Candida glabrata.
    Antimicrob Agents Chemother. 2025 Jan 24:e0134924. doi: 10.1128/aac.01349.
    PubMed     Abstract available


  36. VOGENSEN VB, Singh S, Allende CJ, Engelthaler DM, et al
    Fluoroquinolones and rifampin combination in the backdrop of heteroresistant tuberculosis.
    Antimicrob Agents Chemother. 2025 Jan 16:e0108424. doi: 10.1128/aac.01084.
    PubMed     Abstract available


  37. SADER HS, Smart JI, Mendes RE, Castanheira M, et al
    Ceftobiprole activity against multidrug-resistant Staphylococcus aureus clinical isolates collected in the United States from 2016 through 2022.
    Antimicrob Agents Chemother. 2025 Jan 13:e0140224. doi: 10.1128/aac.01402.
    PubMed     Abstract available


    December 2024
  38. JEHANNE Q, Benejat L, Ducournau A, Aptel J, et al
    Increasing rates of erm(B) and erm(N) in human Campylobacter coli and Campylobacter jejuni erythromycin-resistant isolates between 2018 and 2023 in France.
    Antimicrob Agents Chemother. 2024 Dec 31:e0166824. doi: 10.1128/aac.01668.
    PubMed     Abstract available


  39. OLLINGER TL, Zarnowski R, Parker JE, Kelly SL, et al
    Genetic interaction analysis of Candida glabrata transcription factors CST6 and UPC2A in the regulation of respiration and fluconazole susceptibility.
    Antimicrob Agents Chemother. 2024 Dec 23:e0129424. doi: 10.1128/aac.01294.
    PubMed     Abstract available


  40. ZAGALIOTIS P, Michalik-Provasek J, Mavridou E, Naing E, et al
    Bacteriophage treatment is effective against carbapenem-resistant Klebsiella pneumoniae (KPC) in a neutropenic murine model of gastrointestinal translocation and renal infection.
    Antimicrob Agents Chemother. 2024 Dec 20:e0091924. doi: 10.1128/aac.00919.
    PubMed     Abstract available


  41. GHATBALE P, Sah GP, Dunham S, Khong E, et al
    In vitro resensitization of multidrug-resistant clinical isolates of Enterococcus faecium and E. faecalis through phage-antibiotic synergy.
    Antimicrob Agents Chemother. 2024 Dec 19:e0074024. doi: 10.1128/aac.00740.
    PubMed     Abstract available


  42. HIRAYAMA T, Miyazaki T, Tanaka R, Kitahori N, et al
    TAC1b mutation in Candida auris decreases manogepix susceptibility owing to increased CDR1 expression.
    Antimicrob Agents Chemother. 2024 Dec 18:e0150824. doi: 10.1128/aac.01508.
    PubMed     Abstract available


  43. HEINE HS, Purcell BK, Duncan C, Miller L, et al
    Evaluation of a potent LpxC inhibitor for post-exposure prophylaxis treatment of antibiotic-resistant Burkholderia pseudomallei in a murine infection model.
    Antimicrob Agents Chemother. 2024 Dec 13:e0129524. doi: 10.1128/aac.01295.
    PubMed     Abstract available


  44. BLANCO-MARTIN T, Gonzalez-Pinto L, Aja-Macaya P, Rodriguez-Pallares S, et al
    Mutant prevention concentrations, in vitro resistance evolution dynamics, and mechanisms of resistance to imipenem and imipenem/relebactam in carbapenem-susceptible Klebsiella pneumoniae isolates showing ceftazidime/avibactam resistance.
    Antimicrob Agents Chemother. 2024;68:e0112024.
    PubMed     Abstract available


  45. LE TM, Eubank TA, McKelvey AM, Cao X, et al
    Fidaxomicin resistance in Clostridioides difficile: a systematic review and predictive modeling with RNA polymerase binding sites.
    Antimicrob Agents Chemother. 2024;68:e0120624.
    PubMed     Abstract available


  46. ZHAO H, Hu Y, Nie D, Li N, et al
    A peptide targeting outer membrane protein A of Acinetobacter baumannii exhibits antibacterial activity by reducing bacterial pathogenicity.
    Antimicrob Agents Chemother. 2024;68:e0056524.
    PubMed     Abstract available


  47. RODRIGUEZ-PALLARES S, Blanco-Martin T, Lence E, Aja-Macaya P, et al
    In vivo emergence of resistance to ceftazidime/avibactam through modification of chromosomal AmpC beta-lactamase in Klebsiella aerogenes.
    Antimicrob Agents Chemother. 2024;68:e0130724.
    PubMed     Abstract available


  48. XU T, Wu W, Huang L, Liu B, et al
    Novel plasmid-mediated CMY variant (CMY-192) conferring ceftazidime-avibactam resistance in multidrug-resistant Escherichia coli.
    Antimicrob Agents Chemother. 2024;68:e0090624.
    PubMed     Abstract available


  49. WANG L, Li Y, Xiu L, Hu L, et al
    Multigeographic clinical assessment of a molecular diagnostic assay for detection of key codons to predict decreased susceptibility or resistance to cephalosporins in Neisseria gonorrhoeae.
    Antimicrob Agents Chemother. 2024;68:e0116524.
    PubMed     Abstract available


  50. YANG C, Wang L, Lv J, Wen Y, et al
    Effects of different carbapenemase and siderophore production on cefiderocol susceptibility in Klebsiella pneumoniae.
    Antimicrob Agents Chemother. 2024;68:e0101924.
    PubMed     Abstract available


  51. ARAGAW WW, Gebresilase TT, Negatu DA, Dartois V, et al
    Multidrug tolerance conferred by loss-of-function mutations in anti-sigma factor RshA of Mycobacterium abscessus.
    Antimicrob Agents Chemother. 2024;68:e0105124.
    PubMed     Abstract available


  52. MELENDEZ JH, Edwards VL, Muniz Tirado A, Hardick J, et al
    Local emergence and global evolution of Neisseria gonorrhoeae with high-level resistance to azithromycin.
    Antimicrob Agents Chemother. 2024;68:e0092724.
    PubMed     Abstract available


    November 2024
  53. BUSH NG, Diez-Santos I, Sankara Krishna P, Clavijo B, et al
    Insights into antibiotic resistance promoted by quinolone exposure.
    Antimicrob Agents Chemother. 2024 Nov 26:e0099724. doi: 10.1128/aac.00997.
    PubMed     Abstract available


  54. JIA H, Li X, Zhuang Y, Wu Y, et al
    Neural network-based predictions of antimicrobial resistance phenotypes in multidrug-resistant Acinetobacter baumannii from whole genome sequencing and gene expression.
    Antimicrob Agents Chemother. 2024 Nov 14:e0144624. doi: 10.1128/aac.01446.
    PubMed     Abstract available


  55. HERRERA C, Gomis-Font MA, Lopez-Causape C, Diez-Aguilar M, et al
    Mechanisms leading to in vivo ceftazidime/avibactam resistance development during treatment of GES-5-producing Pseudomonas aeruginosa infections.
    Antimicrob Agents Chemother. 2024;68:e0116424.
    PubMed     Abstract available


  56. BLANCO-MARTIN T, Lopez-Hernandez I, Aracil B, Gonzalez-Pinto L, et al
    Assessment of the activity and mechanisms of resistance to cefiderocol and combinations of beta-lactams and the novel beta-lactamase inhibitors avibactam, taniborbactam, zidebactam, nacubactam, xeruborbactam, and ANT3310 in emerging double-carbapenema
    Antimicrob Agents Chemother. 2024;68:e0092424.
    PubMed     Abstract available


  57. SATTLER J, Ernst CM, Zweigner J, Hamprecht A, et al
    High frequency of acquired virulence factors in carbapenemase-producing Klebsiella pneumoniae isolates from a large German university hospital, 2013-2021.
    Antimicrob Agents Chemother. 2024;68:e0060224.
    PubMed     Abstract available


  58. PUUMALA E, Nabeela S, Thornburg CC, Grkovic T, et al
    Naamidine A reveals a promising zinc-binding strategy for topical antifungal therapy.
    Antimicrob Agents Chemother. 2024;68:e0119424.
    PubMed     Abstract available


  59. SEREME Y, Faury H, Gravrand V, Ageron E, et al
    Molecular insights into the evolutionary trajectory of a Klebsiella aerogenes clinical isolate with a complex trade-off between resistance and virulence.
    Antimicrob Agents Chemother. 2024;68:e0103624.
    PubMed     Abstract available


  60. MARTIN MJ, Luo TL, Kovalchuk V, Kondratiuk V, et al
    Detection of cefiderocol and aztreonam/avibactam resistance in epidemic Escherichia coli ST-361 carrying bla(NDM-5) and bla(KPC-3) from foreign fighters evacuated from Ukraine.
    Antimicrob Agents Chemother. 2024;68:e0109024.
    PubMed     Abstract available


  61. OKE MT, Martz K, Mocanita M, Knezevic S, et al
    Analysis of Acinetobacter P-type type IV secretion system-encoding plasmid diversity uncovers extensive secretion system conservation and diverse antibiotic resistance determinants.
    Antimicrob Agents Chemother. 2024 Nov 4:e0103824. doi: 10.1128/aac.01038.
    PubMed     Abstract available


    October 2024
  62. KON H, Lurie-Weinberger MN, Bechor M, Temkin E, et al
    bla(GES)-producing ST654 comprises a quarter of all carbapenem-resistant Pseudomonas aeruginosa in blood isolates from 15 hospitals.
    Antimicrob Agents Chemother. 2024 Oct 31:e0096524. doi: 10.1128/aac.00965.
    PubMed     Abstract available


  63. LI J, Brandalise D, Coste AT, Sanglard D, et al
    Exploration of novel mechanisms of azole resistance in Candida auris.
    Antimicrob Agents Chemother. 2024 Oct 31:e0126524. doi: 10.1128/aac.01265.
    PubMed     Abstract available


  64. MA Z, Zeng W, Liu H, Chen H, et al
    Characterization of novel sequence type 12531 and O8:H7 serotype carbapenem-resistant Escherichia coli with strong swimming and intestinal epithelial cell barrier migration abilities.
    Antimicrob Agents Chemother. 2024 Oct 23:e0080524. doi: 10.1128/aac.00805.
    PubMed     Abstract available


  65. ZARSKE M, Werckenthin C, Golz JC, Stingl K, et al
    The point mutation A1387G in the 16S rRNA gene confers aminoglycoside resistance in Campylobacter jejuni and Campylobacter coli.
    Antimicrob Agents Chemother. 2024 Oct 15:e0083324. doi: 10.1128/aac.00833.
    PubMed     Abstract available


  66. KENT AG, Spicer LM, Campbell D, Breaker E, et al
    Sentinel Surveillance reveals phylogenetic diversity and detection of linear plasmids harboring vanA and optrA among enterococci collected in the United States.
    Antimicrob Agents Chemother. 2024 Oct 15:e0059124. doi: 10.1128/aac.00591.
    PubMed     Abstract available


  67. HONG H, Fan L, Shi W, Zhu Y, et al
    Overexpression of beta-lactamase genes (bla(KPC,) bla(SHV)) and novel CirA deficiencies contribute to decreased cefiderocol susceptibility in carbapenem-resistant Klebsiella pneumoniae before its approval in China.
    Antimicrob Agents Chemother. 2024 Oct 10:e0075424. doi: 10.1128/aac.00754.
    PubMed     Abstract available


  68. SALAMA EA, Elgammal Y, Utturkar SM, Lanman NA, et al
    Overcoming amphotericin B resistance in Candida auris using the antiemetic drug rolapitant.
    Antimicrob Agents Chemother. 2024 Oct 10:e0055624. doi: 10.1128/aac.00556.
    PubMed     Abstract available


  69. KAUR JN, Klem JF, Liu Y, Boissonneault KR, et al
    Maximally precise combinations to overcome metallo-beta-lactamase-producing Klebsiella pneumoniae.
    Antimicrob Agents Chemother. 2024;68:e0077024.
    PubMed     Abstract available


  70. LI H, Oliver A, Shields RK, Kamat S, et al
    Molecular characterization of clinically isolated Pseudomonas aeruginosa with varying resistance to ceftazidime-avibactam and ceftolozane-tazobactam collected as a part of the ATLAS global surveillance program from 2020 to 2021.
    Antimicrob Agents Chemother. 2024;68:e0067024.
    PubMed     Abstract available


  71. STURARO MC, Damaceno NdS, Faccin ID, Silva ON, et al
    Synergistic antimicrobial combination of third-generation cephalosporins and polymyxin B against carbapenem-polymyxin-resistant Klebsiella pneumoniae: an in vitro and in vivo analysis.
    Antimicrob Agents Chemother. 2024;68:e0093024.
    PubMed     Abstract available


  72. HUANG H, Yang H, Feng S, Zhang X, et al
    High salt condition alters LPS synthesis and induces the emergence of drug resistance mutations in Helicobacter pylori.
    Antimicrob Agents Chemother. 2024;68:e0058724.
    PubMed     Abstract available


  73. RUBIO J, Yan J, Miller S, Cheng J, et al
    Polymyxins retain in vitro activity and in vivo efficacy against "resistant" Acinetobacter baumannii strains when tested in physiological conditions.
    Antimicrob Agents Chemother. 2024;68:e0072524.
    PubMed     Abstract available


  74. SINGH V, Nandanwar H
    IMT-P8 potentiates Gram-positive specific antibiotics in intrinsically resistant Gram-negative bacteria.
    Antimicrob Agents Chemother. 2024;68:e0075324.
    PubMed     Abstract available


  75. HAREZA DA, Cosgrove SE, Bonomo RA, Dzintars K, et al
    Clinical outcomes and emergence of resistance of Pseudomonas aeruginosa infections treated with ceftolozane-tazobactam versus ceftazidime-avibactam.
    Antimicrob Agents Chemother. 2024;68:e0090724.
    PubMed     Abstract available


  76. WOOD GE, Lee JW, Peramuna T, Wendt KL, et al
    The fungal natural product fusidic acid demonstrates potent activity against Mycoplasma genitalium.
    Antimicrob Agents Chemother. 2024;68:e0100624.
    PubMed     Abstract available


  77. GAONA M, Corral J, Campoy S, Barbe J, et al
    The novel MFS efflux pump SxtP, regulated by the LysR-type transcriptional activator SxtR, is involved in the susceptibility to sulfamethoxazole/trimethoprim (SXT) and the pathogenesis of Acinetobacter baumannii.
    Antimicrob Agents Chemother. 2024;68:e0071224.
    PubMed     Abstract available


  78. KOLLER BH, Jania LA, Li H, Barker WT, et al
    Adjuvants restore colistin sensitivity in mouse models of highly colistin-resistant isolates, limiting bacterial proliferation and dissemination.
    Antimicrob Agents Chemother. 2024;68:e0067124.
    PubMed     Abstract available


  79. ALLAIN M, Morel-Journel T, Condamine B, Gibeaux B, et al
    IncC plasmid genome rearrangements influence the vertical and horizontal transmission tradeoff in Escherichia coli.
    Antimicrob Agents Chemother. 2024;68:e0055424.
    PubMed     Abstract available


  80. DUBEY V, Farrington N, Harper N, Johnson A, et al
    Acinetobacter baumannii transformants expressing oxacillinases and metallo-beta-lactamases that confer resistance to meropenem: new tools for anti-Acinetobacter drug development and AMR preparedness.
    Antimicrob Agents Chemother. 2024;68:e0022224.
    PubMed     Abstract available


  81. XU J-Y, Dong H-h, Liao L-j, Yang S-x, et al
    Deoxyshikonin: a promising lead drug grass against drug resistance or sensitivity to Helicobacter pylori in an acidic environment.
    Antimicrob Agents Chemother. 2024;68:e0095924.
    PubMed     Abstract available


  82. YASMIN M, Marshall SH, Chen L, Rhoads DD, et al
    A molecular analysis of meropenem-vaborbactam non-susceptible KPC-producing Klebsiella pneumoniae.
    Antimicrob Agents Chemother. 2024;68:e0020824.
    PubMed     Abstract available


  83. FUKUSHIMA K, Matsumoto Y, Abe Y, Hashimoto K, et al
    Variability of macrolide-resistant profile in Mycobacterium avium complex pulmonary disease.
    Antimicrob Agents Chemother. 2024 Oct 8:e0121324. doi: 10.1128/aac.01213.
    PubMed     Abstract available


    September 2024
  84. RHODES J, Jacobs J, Dennis EK, Manjari SR, et al
    What makes Candida auris pan-drug resistant? Integrative insights from genomic, transcriptomic, and phenomic analysis of clinical strains resistant to all four major classes of antifungal drugs.
    Antimicrob Agents Chemother. 2024 Sep 19:e0091124. doi: 10.1128/aac.00911.
    PubMed     Abstract available


  85. CASTANHEIRA M, Deshpande LM, Rhomberg PR, Carvalhaes CG, et al
    Recent increase in Candida auris frequency in the SENTRY surveillance program: antifungal activity and genotypic characterization.
    Antimicrob Agents Chemother. 2024 Sep 12:e0057024. doi: 10.1128/aac.00570.
    PubMed     Abstract available


  86. LE RUN E, Tettelin H, Holland SM, Zelazny AM, et al
    Evolution toward extremely high imipenem resistance in Mycobacterium abscessus outbreak strains.
    Antimicrob Agents Chemother. 2024 Sep 10:e0067324. doi: 10.1128/aac.00673.
    PubMed     Abstract available


  87. KOMORI K, Aoki K, Harada S, Ishii Y, et al
    Plasmid-mediated acquisition and chromosomal integration of bla(CTX-M-14) in a subclade of Escherichia coli ST131-H30 clade C1.
    Antimicrob Agents Chemother. 2024;68:e0081724.
    PubMed     Abstract available


  88. XUE J, Li S, Wang L, Zhao Y, et al
    Enhanced fatty acid biosynthesis by Sigma28 in stringent responses contributes to multidrug resistance and biofilm formation in Helicobacter pylori.
    Antimicrob Agents Chemother. 2024;68:e0085024.
    PubMed     Abstract available


    August 2024
  89. MARTINI MC, Alonso MN, Cafiero JH, Xiao J, et al
    Loss of glycerol catabolism confers carbon-source-dependent artemisinin resistance in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2024 Aug 28:e0064524. doi: 10.1128/aac.00645.
    PubMed     Abstract available


  90. TIAN P, Li Q-Q, Guo M-J, Zhu Y-Z, et al
    Zidovudine in synergistic combination with nitrofurantoin or omadacycline: in vitro and in murine urinary tract or lung infection evaluation against multidrug-resistant Klebsiella pneumoniae.
    Antimicrob Agents Chemother. 2024 Aug 28:e0034424. doi: 10.1128/aac.00344.
    PubMed     Abstract available


  91. TAO L, Dahlquist A, Harris H, Jacobs E, et al
    Multicenter evaluation of activity of aztreonam in combination with avibactam, relebactam, and vaborbactam against metallo-beta-lactamase-producing carbapenem-resistant gram-negative bacilli.
    Antimicrob Agents Chemother. 2024 Aug 19:e0069324. doi: 10.1128/aac.00693.
    PubMed     Abstract available


  92. HEINE HS, Drusano G, Purcell BK, Anastasiou D, et al
    Omadacycline is active in vitro and in vivo against ciprofloxacin-resistant Bacillus anthracis.
    Antimicrob Agents Chemother. 2024 Aug 12:e0059524. doi: 10.1128/aac.00595.
    PubMed     Abstract available


  93. JACOBS MR, Abdelhamed AM, Good CE, Mack AR, et al
    ARGONAUT-III and -V: susceptibility of carbapenem-resistant Klebsiella pneumoniae and multidrug-resistant Pseudomonas aeruginosa to the bicyclic boronate beta-lactamase inhibitor taniborbactam combined with cefepime.
    Antimicrob Agents Chemother. 2024 Aug 12:e0075124. doi: 10.1128/aac.00751.
    PubMed     Abstract available


  94. ROTONDO CM, Wright GD
    Efficacy of aspergillomarasmine A/meropenem combinations with and without avibactam against bacterial strains producing multiple beta-lactamases.
    Antimicrob Agents Chemother. 2024 Aug 12:e0027224. doi: 10.1128/aac.00272.
    PubMed     Abstract available


  95. EISHA S, Morris AJ, Martin I, Yau YCW, et al
    Effect of L-arginine on cystic fibrosis Pseudomonas aeruginosa biofilms.
    Antimicrob Agents Chemother. 2024;68:e0033624.
    PubMed     Abstract available


  96. EGGE SL, Rizvi SA, Simar SR, Alcalde M, et al
    Cefiderocol heteroresistance associated with mutations in TonB-dependent receptor genes in Pseudomonas aeruginosa of clinical origin.
    Antimicrob Agents Chemother. 2024;68:e0012724.
    PubMed     Abstract available


  97. PONTA G, Morena V, Strano M, Molteni C, et al
    Safety of rezafungin as a long-term treatment option in two patients with complicated fungal infections: two cases from Lecco Hospital (Italy).
    Antimicrob Agents Chemother. 2024;68:e0075024.
    PubMed     Abstract available


    July 2024
  98. NELSON ME, Little JL, Kristich CJ
    Pbp4 provides transpeptidase activity to the FtsW-PbpB peptidoglycan synthase to drive cephalosporin resistance in Enterococcus faecalis.
    Antimicrob Agents Chemother. 2024 Jul 26:e0055524. doi: 10.1128/aac.00555.
    PubMed     Abstract available


  99. ADELMAN MW, Andes DR
    Case Commentary: Extending our therapeutic range against multidrug-resistant Candida.
    Antimicrob Agents Chemother. 2024 Jul 22:e0084724. doi: 10.1128/aac.00847.
    PubMed     Abstract available


  100. TRUONG-BOLDUC QC, Wang Y, Lawton BG, Brown Harding H, et al
    Phenazine-1 carboxylic acid of Pseudomonas aeruginosa induces the expression of Staphylococcus aureus Tet38 MDR efflux pump and mediates resistance to phenazines and antibiotics.
    Antimicrob Agents Chemother. 2024 Jul 19:e0063624. doi: 10.1128/aac.00636.
    PubMed     Abstract available


  101. GIGANTE V, Alm RA, Melchiorri D, Rocke T, et al
    Multi-year analysis of the global preclinical antibacterial pipeline: trends and gaps.
    Antimicrob Agents Chemother. 2024 Jul 15:e0053524. doi: 10.1128/aac.00535.
    PubMed     Abstract available


  102. STRAHILEVITZ J, Motro Y, Temper V, Merezhko D, et al
    In vivo selection of carbapenem resistance during persistent Klebsiella pneumoniae sequence type 395 bloodstream infection due to OmpK36 deletion.
    Antimicrob Agents Chemother. 2024 Jul 11:e0066324. doi: 10.1128/aac.00663.
    PubMed     Abstract available


  103. DULYAYANGKUL P, Sealey JE, Lee WWY, Satapoomin N, et al
    Improving nitrofurantoin resistance prediction in Escherichia coli from whole-genome sequence by integrating NfsA/B enzyme assays.
    Antimicrob Agents Chemother. 2024;68:e0024224.
    PubMed     Abstract available


  104. BEREDAKI M-I, Arendrup MC, Pournaras S, Meletiadis J, et al
    Comparative pharmacodynamics and dose optimization of liposomal amphotericin B against Candida species in an in vitro pharmacokinetic/pharmacodynamic model.
    Antimicrob Agents Chemother. 2024 Jul 3:e0022524. doi: 10.1128/aac.00225.
    PubMed     Abstract available


    June 2024
  105. MA Y, Pirolo M, Jana B, Mebus VH, et al
    The intrinsic macrolide resistome of Escherichia coli.
    Antimicrob Agents Chemother. 2024 Jun 28:e0045224. doi: 10.1128/aac.00452.
    PubMed     Abstract available


  106. KURTZHALS ML, Norman A, Svensson E, Lillebaek T, et al
    Applying whole genome sequencing to predict phenotypic drug resistance in Mycobacterium tuberculosis: leveraging 20 years of nationwide data from Denmark.
    Antimicrob Agents Chemother. 2024 Jun 21:e0043024. doi: 10.1128/aac.00430.
    PubMed     Abstract available


  107. PLUMET L, Magnan C, Ahmad-Mansour N, Sotto A, et al
    The zebrafish embryo model: unveiling its potential for investigating phage therapy against methicillin-resistant Staphylococcus aureus infection.
    Antimicrob Agents Chemother. 2024 Jun 20:e0056124. doi: 10.1128/aac.00561.
    PubMed     Abstract available


  108. SON JE, Park SH, Choi U, Lee C-R, et al
    Lytic transglycosylase repertoire diversity enables intrinsic antibiotic resistance and daughter cell separation in Escherichia coli under acidic stress.
    Antimicrob Agents Chemother. 2024 Jun 17:e0037224. doi: 10.1128/aac.00372.
    PubMed     Abstract available


  109. DIAMOND TL, Goh SL, Ngo W, Rodriguez S, et al
    No antagonism or cross-resistance and a high barrier to the emergence of resistance in vitro for the combination of islatravir and lenacapavir.
    Antimicrob Agents Chemother. 2024 Jun 12:e0033424. doi: 10.1128/aac.00334.
    PubMed     Abstract available


  110. PETERSIEL N, Giulieri S, Daniel DS, Fan S-H, et al
    Genomic investigation and clinical correlates of the in vitro beta-lactam: NaHCO(3) responsiveness phenotype among methicillin-resistant Staphylococcus aureus isolates from a randomized clinical trial.
    Antimicrob Agents Chemother. 2024 Jun 5:e0021824. doi: 10.1128/aac.00218.
    PubMed     Abstract available


  111. MINUK LM, Brode SK, Mehrabi M, Sharma MK, et al
    Phenotypic amikacin resistance may not indicate poor response to amikacin in Mycobacterium avium complex pulmonary disease.
    Antimicrob Agents Chemother. 2024;68:e0008424.
    PubMed     Abstract available


    May 2024
  112. HUANG E, Thompson RN, Moon SH, Keck JM, et al
    Treatment-emergent cefiderocol resistance in carbapenem-resistant Acinetobacter baumannii is associated with insertion sequence ISAba36 in the siderophore receptor pirA.
    Antimicrob Agents Chemother. 2024 May 29:e0029024. doi: 10.1128/aac.00290.
    PubMed     Abstract available


  113. ANOY MMI, Kim W-J, Gelston S, Fleming D, et al
    Evaluation of treatment of methicillin-resistant Staphylococcus aureus biofilms with intermittent electrochemically generated H(2)O(2) or HOCl.
    Antimicrob Agents Chemother. 2024 May 21:e0172223. doi: 10.1128/aac.01722.
    PubMed     Abstract available


  114. LUO J, Liu M, Ai W, Zheng X, et al
    Synergy of lytic phage pB23 and meropenem combination against carbapenem-resistant Acinetobacter baumannii.
    Antimicrob Agents Chemother. 2024 May 14:e0044824. doi: 10.1128/aac.00448.
    PubMed     Abstract available


  115. BERGIN S, Doorley LA, Rybak JM, Wolfe KH, et al
    Analysis of clinical Candida parapsilosis isolates reveals copy number variation in key fluconazole resistance genes.
    Antimicrob Agents Chemother. 2024 May 7:e0161923. doi: 10.1128/aac.01619.
    PubMed     Abstract available


  116. TAKEMOTO K, Nakayama R, Fujimoto K, Suzuki Y, et al
    In vitro and in vivo activities of KSP-1007, a broad-spectrum inhibitor of serine- and metallo-beta-lactamases, in combination with meropenem against carbapenem-resistant Gram-negative bacteria.
    Antimicrob Agents Chemother. 2024 May 6:e0160223. doi: 10.1128/aac.01602.
    PubMed     Abstract available


  117. SCHALKWIJK HH, Shewakramani NR, Das K, Andrei G, et al
    Combination of ganciclovir and trifluridine prevents drug-resistance emergence in HSV-1.
    Antimicrob Agents Chemother. 2024;68:e0011024.
    PubMed     Abstract available


  118. VEGA AD, DeRonde K, Jimenez A, Piazza M, et al
    Difficult-to-treat (DTR) Pseudomonas aeruginosa harboring Verona-Integron metallo-beta-lactamase (bla(VIM)): infection management and molecular analysis.
    Antimicrob Agents Chemother. 2024;68:e0147423.
    PubMed     Abstract available


  119. MILLER AA, Moussa SH, McLeod SM
    Characterization of Acinetobacter baumannii-calcoaceticus complex isolates and microbiological outcome for patients treated with sulbactam-durlobactam in a phase 3 trial (ATTACK).
    Antimicrob Agents Chemother. 2024;68:e0169823.
    PubMed     Abstract available


  120. ISHII M, Yamada T, Ishikawa K, Ichinose K, et al
    The Ptk2-Pma1 pathway enhances tolerance to terbinafine in Trichophyton rubrum.
    Antimicrob Agents Chemother. 2024;68:e0160923.
    PubMed     Abstract available


  121. GHOSH S, Orman MA
    Exploring the links between SOS response, mutagenesis, and resistance during the recovery period.
    Antimicrob Agents Chemother. 2024;68:e0146223.
    PubMed     Abstract available


  122. CASTANHEIRA M, Kimbrough JH, Lindley J, Doyle TB, et al
    In vitro development of resistance against antipseudomonal agents: comparison of novel beta-lactam/beta-lactamase inhibitor combinations and other beta-lactam agents.
    Antimicrob Agents Chemother. 2024;68:e0136323.
    PubMed     Abstract available


  123. XIA L, Li Y, Wang Y, Zhou H, et al
    Quorum-sensing regulation of phenazine production heightens Pseudomonas aeruginosa resistance to ciprofloxacin.
    Antimicrob Agents Chemother. 2024;68:e0011824.
    PubMed     Abstract available


  124. SUZUKI D, Sakurai A, Wakuda M, Suzuki M, et al
    Clinical and genomic characteristics of IMP-producing Enterobacter cloacae complex and Klebsiella pneumoniae.
    Antimicrob Agents Chemother. 2024;68:e0167223.
    PubMed     Abstract available


  125. NIELSEN TK, Petersen IB, Xu L, Barbuti MD, et al
    The Spx stress regulator confers high-level beta-lactam resistance and decreases susceptibility to last-line antibiotics in methicillin-resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 2024 May 1:e0033524. doi: 10.1128/aac.00335.
    PubMed     Abstract available


    April 2024
  126. PETRAITIS V, Petraitiene R, Kavaliauskas P, Naing E, et al
    Development of rabbit models of ventilator-associated bacterial pneumonia produced by carbapenem-resistant Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2024 Apr 30:e0020524. doi: 10.1128/aac.00205.
    PubMed     Abstract available


  127. SHAFER WM, Conn GL
    Ensuring a sustained workforce to combat antibiotic resistance in the 21st century: the critical need for training the next-gen of scientists at the pre-doctoral level.
    Antimicrob Agents Chemother. 2024 Apr 19:e0024424. doi: 10.1128/aac.00244.
    PubMed     Abstract available


  128. LYU Z, Ling Y, van Hoof A, Ling J, et al
    Inactivation of the ribosome assembly factor RimP causes streptomycin resistance and impairs motility in Salmonella.
    Antimicrob Agents Chemother. 2024 Apr 17:e0000224. doi: 10.1128/aac.00002.
    PubMed     Abstract available


  129. HARTUIS S, Ourliac-Garnier I, Robert E, Albassier M, et al
    Precise genome editing underlines the distinct contributions of mutations in ERG11, ERG3, MRR1, and TAC1 genes to antifungal resistance in Candida parapsilosis.
    Antimicrob Agents Chemother. 2024 Apr 16:e0002224. doi: 10.1128/aac.00022.
    PubMed     Abstract available


  130. LOSSOUARN J, Beurrier E, Bouteau A, Moncaut E, et al
    The virtue of training: extending phage host spectra against vancomycin-resistant Enterococcus faecium strains using the Appelmans method.
    Antimicrob Agents Chemother. 2024 Apr 9:e0143923. doi: 10.1128/aac.01439.
    PubMed     Abstract available


  131. TENG T, Chen S, Huo F, Jia J, et al
    Efflux pump effects on levofloxacin resistance in Mycobacterium abscessus.
    Antimicrob Agents Chemother. 2024 Apr 4:e0134823. doi: 10.1128/aac.01348.
    PubMed     Abstract available


  132. SHANG Y, Zhang Y, Wang R, Peng Y, et al
    Deciphering the molecular and functional basis of TMexCD1: the plasmid-encoded efflux pump of resistance-nodulation-division superfamily.
    Antimicrob Agents Chemother. 2024;68:e0167823.
    PubMed     Abstract available


  133. RIBEIRO DOS SANTOS A, Gade L, Misas E, Litvintseva AP, et al
    Bimodal distribution of azole susceptibility in Sporothrix brasiliensis isolates in Brazil.
    Antimicrob Agents Chemother. 2024;68:e0162023.
    PubMed     Abstract available


  134. TAIT JR, Anderson D, Nation RL, Creek DJ, et al
    Identifying and mathematically modeling the time-course of extracellular metabolic markers associated with resistance to ceftolozane/tazobactam in Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2024;68:e0108123.
    PubMed     Abstract available


  135. YANO H, Hayashi W, Kawakami S, Aoki S, et al
    Nationwide genome surveillance of carbapenem-resistant Pseudomonas aeruginosa in Japan.
    Antimicrob Agents Chemother. 2024 Apr 2:e0166923. doi: 10.1128/aac.01669.
    PubMed     Abstract available


    March 2024
  136. MAIA AR, Cezard A, Fouquenet D, Vasseur V, et al
    Preventive nasal administration of flagellin restores antimicrobial effect of gentamicin and protects against a multidrug-resistant strain of Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2024 Mar 25:e0136123. doi: 10.1128/aac.01361.
    PubMed     Abstract available


  137. SEGAWA T, Masuda K, Hisatsune J, Ishida-Kuroki K, et al
    Genomic analysis of inter-hospital transmission of vancomycin-resistant Enterococcus faecium sequence type 80 isolated during an outbreak in Hiroshima, Japan.
    Antimicrob Agents Chemother. 2024 Mar 20:e0171623. doi: 10.1128/aac.01716.
    PubMed     Abstract available


  138. SUN L, Zhuang H, Chen M, Chen Y, et al
    Vancomycin heteroresistance caused by unstable tandem amplifications of the vanM gene cluster on linear conjugative plasmids in a clinical Enterococcus faecium.
    Antimicrob Agents Chemother. 2024 Mar 20:e0115923. doi: 10.1128/aac.01159.
    PubMed     Abstract available


  139. LI W, He Z, Di W, Xu W, et al
    Transposition mechanism of ISApl1-the determinant of colistin resistance dissemination.
    Antimicrob Agents Chemother. 2024;68:e0123123.
    PubMed     Abstract available


  140. ANDRE C, Van Camp AG, Ung L, Gilmore MS, et al
    Characterization of the resistome and predominant genetic lineages of Gram-positive bacteria causing keratitis.
    Antimicrob Agents Chemother. 2024;68:e0124723.
    PubMed     Abstract available


  141. CARUSO L, Mellini M, Catalano Gonzaga O, Astegno A, et al
    Hydrogen sulfide production does not affect antibiotic resistance in Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2024 Mar 6:e0007524. doi: 10.1128/aac.00075.
    PubMed     Abstract available


    February 2024
  142. ZHANG M, Yang B, Shi J, Wang Z, et al
    Host defense peptides mitigate the spread of antibiotic resistance in physiologically relevant condition.
    Antimicrob Agents Chemother. 2024 Feb 28:e0126123. doi: 10.1128/aac.01261.
    PubMed     Abstract available


  143. MULATO A, Lansdon E, Aoyama R, Voigt J, et al
    Preclinical characterization of a non-peptidomimetic HIV protease inhibitor with improved metabolic stability.
    Antimicrob Agents Chemother. 2024 Feb 21:e0137323. doi: 10.1128/aac.01373.
    PubMed     Abstract available


  144. FREIBERG JA, Tao L, Manuel C, Mike LA, et al
    A multi-species outbreak of VIM-producing carbapenem-resistant bacteria in a burn unit and subsequent investigation of rapid development of cefiderocol resistance.
    Antimicrob Agents Chemother. 2024 Feb 20:e0150723. doi: 10.1128/aac.01507.
    PubMed     Abstract available


  145. BASSERES E, Eubank TA, Begum K, Alam MJ, et al
    Antibacterial activity of ibezapolstat against antimicrobial-resistant clinical strains of Clostridioides difficile.
    Antimicrob Agents Chemother. 2024 Feb 16:e0162123. doi: 10.1128/aac.01621.
    PubMed     Abstract available


  146. ERSOY SC, Proctor RA, Rose WE, Abdelhady W, et al
    Sensitizing methicillin-resistant Staphylococcus aureus (MRSA) to cefuroxime: the synergic effect of bicarbonate and the wall teichoic acid inhibitor ticlopidine.
    Antimicrob Agents Chemother. 2024 Feb 13:e0162723. doi: 10.1128/aac.01627.
    PubMed     Abstract available


  147. PITOUT JDD, Peirano G, Matsumura Y, DeVinney R, et al
    Escherichia coli sequence type 410 with carbapenemases: a paradigm shift within E. coli toward multidrug resistance.
    Antimicrob Agents Chemother. 2024;68:e0133923.
    PubMed     Abstract available


  148. DRUSIN SI, Le Terrier C, Poirel L, Bonomo RA, et al
    Structural basis of metallo-beta-lactamase resistance to taniborbactam.
    Antimicrob Agents Chemother. 2024;68:e0116823.
    PubMed     Abstract available


    January 2024
  149. JIANG X, Li D, Sun Z, Lu Y, et al
    Type I BREX system defends against antibiotic-resistant plasmids in Escherichia coli.
    Antimicrob Agents Chemother. 2024 Jan 30:e0112823. doi: 10.1128/aac.01128.
    PubMed     Abstract available


  150. IOVLEVA A, McElheny CL, Fowler EL, Cober E, et al
    In vitro activity of sulbactam-durlobactam against colistin-resistant and/or cefiderocol-non-susceptible, carbapenem-resistant Acinetobacter baumannii collected in U.S. hospitals.
    Antimicrob Agents Chemother. 2024 Jan 30:e0125823. doi: 10.1128/aac.01258.
    PubMed     Abstract available


  151. ZALACAIN M, Achard P, Llanos A, Morrissey I, et al
    Meropenem-ANT3310, a unique beta-lactam-beta-lactamase inhibitor combination with expanded antibacterial spectrum against Gram-negative pathogens including carbapenem-resistant Acinetobacter baumannii.
    Antimicrob Agents Chemother. 2024 Jan 30:e0112023. doi: 10.1128/aac.01120.
    PubMed     Abstract available


  152. AXELL-HOUSE DB, Simar SR, Panesso D, Rincon S, et al
    LiaX is a surrogate marker for cell envelope stress and daptomycin non-susceptibility in Enterococcus faecium.
    Antimicrob Agents Chemother. 2024 Jan 30:e0106923. doi: 10.1128/aac.01069.
    PubMed     Abstract available


  153. ALDEJOHANN AM, Menner C, Thielemann N, Martin R, et al
    In vitro activity of ibrexafungerp against clinically relevant echinocandin-resistant Candida strains.
    Antimicrob Agents Chemother. 2024 Jan 11:e0132423. doi: 10.1128/aac.01324.
    PubMed     Abstract available


  154. TERAN N, Egge SL, Phe K, Baptista RP, et al
    The emergence of cefiderocol resistance in Pseudomonas aeruginosa from a heteroresistant isolate during prolonged therapy.
    Antimicrob Agents Chemother. 2024;68:e0100923.
    PubMed     Abstract available


  155. CHEN T, Yao J, Quan K, Xu J, et al
    Repurposing a human acetyl-CoA carboxylase inhibitor firsocostat to treat fungal candidiasis alone and in combination.
    Antimicrob Agents Chemother. 2024;68:e0113123.
    PubMed     Abstract available


    December 2023
  156. TAKEMURA M, Nakamura R, Ota M, Nakai R, et al
    In vitro and in vivo activity of cefiderocol against Achromobacter spp. and Burkholderia cepacia complex, including carbapenem-non-susceptible isolates.
    Antimicrob Agents Chemother. 2023;67:e0034623.
    PubMed     Abstract available


    November 2023
  157. ZHAO J, Pu D, Li Z, Liu X, et al
    In vitro activity of cefiderocol, a siderophore cephalosporin, against carbapenem-resistant hypervirulent Klebsiella pneumoniae in China.
    Antimicrob Agents Chemother. 2023 Nov 28:e0073523. doi: 10.1128/aac.00735.
    PubMed     Abstract available


  158. JIAO F, Bao Y, Li M, Zhang Y, et al
    Unraveling the mechanism of ceftaroline-induced allosteric regulation in penicillin-binding protein 2a: insights for novel antibiotic development against methicillin-resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 2023 Nov 16:e0089523. doi: 10.1128/aac.00895.
    PubMed     Abstract available


  159. DIAZ-GARCIA J, Machado M, Alcala L, Reigadas E, et al
    Trends in antifungal resistance in Candida from a multicenter study conducted in Madrid (CANDIMAD study): fluconazole-resistant C. parapsilosis spreading has gained traction in 2022.
    Antimicrob Agents Chemother. 2023;67:e0098623.
    PubMed     Abstract available


  160. BOSCH A, Macha ME, Ren Q, Kohler P, et al
    Resistance development in Escherichia coli to delafloxacin at pHs 6.0 and 7.3 compared to ciprofloxacin.
    Antimicrob Agents Chemother. 2023;67:e0162522.
    PubMed     Abstract available


  161. SCHILDKRAUT JA, Raaijmakers J, Aarnoutse R, Hoefsloot W, et al
    The role of rifampicin within the treatment of Mycobacterium avium pulmonary disease.
    Antimicrob Agents Chemother. 2023;67:e0087423.
    PubMed     Abstract available


  162. YAMADA T, Maeda M, Nagai H, Salamin K, et al
    Two different types of tandem sequences mediate the overexpression of TinCYP51B in azole-resistant Trichophyton indotineae.
    Antimicrob Agents Chemother. 2023;67:e0093323.
    PubMed     Abstract available


    October 2023
  163. JIANG S, Chen M, Zhang J, Ba X, et al
    Profiling daptomycin resistance among diverse methicillin-resistant Staphylococcus aureus lineages in China.
    Antimicrob Agents Chemother. 2023 Oct 30:e0056323. doi: 10.1128/aac.00563.
    PubMed     Abstract available


  164. ZHANG S-P, Ye Y-P, Hou J, Ye Z-R, et al
    Antitoxin MqsA decreases antibiotic susceptibility through the global regulator AgtR in Pseudomonas fluorescens.
    Antimicrob Agents Chemother. 2023 Oct 25:e0081223. doi: 10.1128/aac.00812.
    PubMed     Abstract available


  165. TAKAHASHI H, Morita M, Kamiya H, Fukusumi M, et al
    Emergence of ciprofloxacin- and penicillin-resistant Neisseria meningitidis isolates in Japan between 2003 and 2020 and its genetic features.
    Antimicrob Agents Chemother. 2023 Oct 24:e0074423. doi: 10.1128/aac.00744.
    PubMed     Abstract available


  166. LAU JZ, Kuo SH, Belo Y, Malach E, et al
    Antibacterial efficacy of an ultra-short palmitoylated random peptide mixture in mouse models of infection by carbapenem-resistant Klebsiella pneumoniae.
    Antimicrob Agents Chemother. 2023 Oct 11:e0057423. doi: 10.1128/aac.00574.
    PubMed     Abstract available


  167. KUHBACHER A, Merschak P, Haas H, Liebl M, et al
    The cytochrome P450 reductase CprA is a rate-limiting factor for Cyp51A-mediated azole resistance in Aspergillus fumigatus.
    Antimicrob Agents Chemother. 2023 Oct 10:e0091823. doi: 10.1128/aac.00918.
    PubMed     Abstract available


  168. LOMOVSKAYA O, Castanheira M, Lindley J, Rubio-Aparicio D, et al
    In vitro potency of xeruborbactam in combination with multiple beta-lactam antibiotics in comparison with other beta-lactam/beta-lactamase inhibitor (BLI) combinations against carbapenem-resistant and extended-spectrum beta-lactamase-producing Enterob
    Antimicrob Agents Chemother. 2023 Oct 6:e0044023. doi: 10.1128/aac.00440.
    PubMed     Abstract available


    September 2023
  169. MIRON-OCAMPO A, Beattie SR, Guin S, Conway T, et al
    CWHM-974 is a fluphenazine derivative with improved antifungal activity against Candida albicans due to reduced susceptibility to multidrug transporter-mediated resistance mechanisms.
    Antimicrob Agents Chemother. 2023 Sep 13:e0056723. doi: 10.1128/aac.00567.
    PubMed     Abstract available


  170. PODOLL JD, Rosen E, Wang W, Gao Y, et al
    A small-molecule membrane fluidizer re-sensitizes methicillin-resistant Staphylococcus aureus (MRSA) to beta-lactam antibiotics.
    Antimicrob Agents Chemother. 2023 Sep 8:e0005123. doi: 10.1128/aac.00051.
    PubMed     Abstract available


Thank you for your interest in scientific medicine.


AMEDEO Drug Resistance is free of charge.