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Articles published in Antimicrob Agents Chemother

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    May 2020
  1. THAPA E, Knauss HM, Colvin BA, Fischer BA, et al
    Persistence Dynamics of Antimicrobial Resistant Neisseria in the Pharynx of Rhesus Macaques.
    Antimicrob Agents Chemother. 2020 May 18. pii: AAC.02232.
    PubMed     Abstract available


  2. KEBRIAEI R, Lev K, Morrisette T, Stamper K, et al
    Bacteriophage-Antibiotic Combination Strategy: An Alternative against Methicillin-resistant Phenotypes of Staphylococcus aureus.
    Antimicrob Agents Chemother. 2020 May 11. pii: AAC.00461.
    PubMed     Abstract available


  3. SFEIR MM
    Methicillin-resistant Staphylococcus aureus (MRSA) nasal screening: Clinical use for excluding diabetic foot infection with MRSA.
    Antimicrob Agents Chemother. 2020 May 11. pii: AAC.00635.
    PubMed     Abstract available


  4. MERGENHAGEN KA, Croix M, Starr KE, Sellick JA, et al
    Reply to Sfeir, "Methicillin-Resistant Staphylococcus aureus (MRSA) Nasal Screening: Clinical Use for Excluding Diabetic Foot Infection with MRSA".
    Antimicrob Agents Chemother. 2020 May 11. pii: AAC.00803.
    PubMed     Abstract available


  5. WILSEY HA, Burgess DR, Burgess DS
    Focusing the lens on the CAMERA concepts: Early combination beta-lactam and vancomycin therapy in methicillin-resistant Staphylococcus aureus bacteremia.
    Antimicrob Agents Chemother. 2020 May 4. pii: AAC.00360.
    PubMed     Abstract available


  6. SHIRAKAWA T, Sekizuka T, Kuroda M, Suzuki S, et al
    Comparative Genomic Analysis of Third Generation Cephalosporin-Resistant Escherichia coli Harboring bla CMY-2-Positive IncI1 group, IncB/O/K/Z, and IncC Plasmids Isolated from Healthy Broilers in Japan.
    Antimicrob Agents Chemother. 2020 May 4. pii: AAC.02385.
    PubMed     Abstract available


    April 2020
  7. SHAH SU, Xiong YQ, Abdelhady W, Iwaz J, et al
    Effect of the Lysin, Exebacase, on Cardiac Vegetation Progression in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus (MRSA) Endocarditis as Determined by Echocardiography.
    Antimicrob Agents Chemother. 2020 Apr 27. pii: AAC.00482.
    PubMed     Abstract available


  8. MOLINA KC, Morrisette T, Miller MA, Huang V, et al
    The Emerging Role of beta-lactams in the Treatment of Methicillin-Resistant Staphylococcus aureus Bloodstream Infections.
    Antimicrob Agents Chemother. 2020 Apr 20. pii: AAC.00468.
    PubMed     Abstract available


  9. NARMANDAKH E, Tumenbayar O, Borolzoi T, Erkhembayar B, et al
    Genetic Mutations Associated with Isoniazid Resistance in Mycobacterium tuberculosis in Mongolia.
    Antimicrob Agents Chemother. 2020 Apr 20. pii: AAC.00537.
    PubMed     Abstract available


  10. HEBERT C, Gao Y, Rahman P, Dewart C, et al
    Prediction of antibiotic susceptibility for urinary tract infection in a hospital setting.
    Antimicrob Agents Chemother. 2020 Apr 20. pii: AAC.02236.
    PubMed     Abstract available


  11. WANG CH, Siu LK, Chang FY, Tsai YK, et al
    A novel deletion mutation in pmrB contributes to concurrent colistin resistance in carbapenem resistant E. coli ST 405 of clinical origin.
    Antimicrob Agents Chemother. 2020 Apr 13. pii: AAC.00220.
    PubMed     Abstract available


    March 2020
  12. YANG T, Pan L, Wu N, Wang L, et al
    Antimicrobial resistance in clinical Ureaplasma spp. and Mycoplasma hominis and structural mechanisms underlying the quinolone resistance.
    Antimicrob Agents Chemother. 2020 Mar 30. pii: AAC.02560.
    PubMed     Abstract available


  13. MASI M, Pinet E, Pages JM
    Complex response of the CpxAR two-component system to beta-lactams on antibiotic resistance and envelop homeostasis in Enterobacteriaceae.
    Antimicrob Agents Chemother. 2020 Mar 30. pii: AAC.00291.
    PubMed     Abstract available


  14. CABRERA NL, Malek AE, Aitken SL, Arias CA, et al
    Outcomes of Patients with Bloodstream Infections Caused by Ampicillin-Susceptible but Penicillin-Resistant Enterococcus faecalis: Caution in Interpreting the Results.
    Antimicrob Agents Chemother. 2020;64.
    PubMed    


  15. FELDGARDEN M, Brover V, Haft DH, Prasad AB, et al
    Erratum for Feldgarden et al., "Validating the AMRFinder Tool and Resistance Gene Database by Using Antimicrobial Resistance Genotype-Phenotype Correlations in a Collection of Isolates".
    Antimicrob Agents Chemother. 2020;64.
    PubMed    


  16. CASTANHEIRA M, Doyle TB, Kantro V, Mendes RE, et al
    Correction for Castanheira et al., "Meropenem-Vaborbactam Activity against Carbapenem-Resistant Enterobacterales Isolates Collected in U.S. Hospitals during 2016 to 2018".
    Antimicrob Agents Chemother. 2020;64.
    PubMed    


  17. KIM D, Lee H, Yoon EJ, Hong JS, et al
    Reply to Cabrera et al., "Outcomes of Patients with Bloodstream Infections Caused by Ampicillin-Susceptible but Penicillin-Resistant Enterococcus faecalis: Caution in Interpreting the Results".
    Antimicrob Agents Chemother. 2020;64.
    PubMed    


  18. CHATTERJEE A, Poon R, Chatterjee SS
    Stp1 loss of function promotes beta-lactam resistance in S. aureus that is independent of classical genes.
    Antimicrob Agents Chemother. 2020 Mar 16. pii: AAC.02222.
    PubMed     Abstract available


  19. SAMUELSEN O, Astrand OAH, Frohlich C, Heikal A, et al
    ZN148 - a modular synthetic metallo-beta-lactamase inhibitor reverses carbapenem-resistance in Gram-negative pathogens in vivo.
    Antimicrob Agents Chemother. 2020 Mar 16. pii: AAC.02415.
    PubMed     Abstract available


  20. MACFADDEN DR, Coburn B, Brinda K, Corbeil A, et al
    Using Genetic Distance from Archived Samples for the Prediction of Antibiotic Resistance in Escherichia coli.
    Antimicrob Agents Chemother. 2020 Mar 9. pii: AAC.02417.
    PubMed     Abstract available


  21. JOHNSTON BD, Thuras P, Porter SB, Anacker M, et al
    Activity of imipenem/relebactam against carbapenem-resistant Escherichia coli isolates from the United States in relation to clonal background, resistance genes, co-resistance, and region.
    Antimicrob Agents Chemother. 2020 Mar 9. pii: AAC.02408.
    PubMed     Abstract available


  22. SCHWENDENER S, Dona V, Perreten V
    The novel macrolide resistance genes mef(D), msr(F) and msr(H) are present on resistance islands in Macrococcus canis, Macrococcus caseolyticus and Staphylococcus aureus.
    Antimicrob Agents Chemother. 2020 Mar 2. pii: AAC.00160.
    PubMed     Abstract available


  23. CUI CY, Chen C, Liu BT, He Q, et al
    Co-occurrence of plasmid-mediated tigecycline and carbapenem resistance in Acinetobacter spp. from waterfowls and their neighboring environment.
    Antimicrob Agents Chemother. 2020 Mar 2. pii: AAC.02502.
    PubMed     Abstract available


    February 2020
  24. JAHANBAKHSH S, Singh NB, Yim J, Kebriaei R, et al
    Impact of Daptomycin Dose Exposure Alone or in Combination with beta- lactams or Rifampin against Vancomycin-Resistant Enterococci (VRE) in an In vitro Biofilm Model.
    Antimicrob Agents Chemother. 2020 Feb 24. pii: AAC.02074.
    PubMed     Abstract available


  25. ACKLEY R, Roshdy D, Meredith J, Minor S, et al
    Meropenem/Vaborbactam versus Ceftazidime/Avibactam for Treatment of Carbapenem-Resistant Enterobacteriaceae Infections.
    Antimicrob Agents Chemother. 2020 Feb 24. pii: AAC.02313.
    PubMed     Abstract available


  26. ERSOY SC, Otmishi M, Milan VT, Li L, et al
    Scope and Predictive Genetic/Phenotypic Signatures of 'Bicarbonate [NaHCO3]-Responsiveness' and beta-Lactam Sensitization Among Methicillin-Resistant Staphylococcus aureus (MRSA).
    Antimicrob Agents Chemother. 2020 Feb 10. pii: AAC.02445.
    PubMed     Abstract available


  27. CHOI S, Moon SM, Park SJ, Lee SC, et al
    Antagonistic effect of colistin on vancomycin activity against methicillin-resistant Staphylococcus aureus in in vitro and in vivo studies.
    Antimicrob Agents Chemother. 2020 Feb 10. pii: AAC.01925.
    PubMed     Abstract available


  28. DJORIC D, Little JL, Kristich CJ
    Multiple low-reactivity class B penicillin-binding proteins are required for cephalosporin resistance in enterococci.
    Antimicrob Agents Chemother. 2020 Feb 10. pii: AAC.02273.
    PubMed     Abstract available


    January 2020
  29. MERGENHAGEN KA, Croix M, Starr KE, Sellick JA, et al
    The utility of methicillin-resistant Staphylococcus aureus nares screening for patients with a diabetic foot infection.
    Antimicrob Agents Chemother. 2020 Jan 27. pii: AAC.02213.
    PubMed     Abstract available


  30. WATERER G, Lord J, Hofmann T, Jouhikainen T, et al
    A Phase I, dose-escalating study of safety and pharmacokinetics of inhaled dry powder vancomycin (AeroVanc) in volunteers and patients with cystic fibrosis: a new approach to therapy for methicillin-resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 2020 Jan 21. pii: AAC.01776.
    PubMed     Abstract available


  31. MILLER CR, Dey S, Smolenski PD, Kulkarni PS, et al
    Distinct Subpopulations of Intravalvular Methicillin-Resistant Staphylococcus aureus With Variable Susceptibility to Daptomycin in Tricuspid Valve Endocarditis.
    Antimicrob Agents Chemother. 2020 Jan 13. pii: AAC.01593.
    PubMed     Abstract available


  32. BIAGI M, Shajee A, Vialichka A, Jurkovic M, et al
    Activity of imipenem-relebactam and meropenem-vaborbactam against carbapenem-resistant SME-producing Serratia marcescens.
    Antimicrob Agents Chemother. 2020 Jan 13. pii: AAC.02255.
    PubMed     Abstract available


  33. ROTONDO CM, Sychantha D, Koteva K, Wright GD, et al
    Suppression of beta-Lactam Resistance by Aspergillomarasmine A is Influenced by Both the Metallo-beta-Lactamase Target and the Antibiotic Partner.
    Antimicrob Agents Chemother. 2020 Jan 13. pii: AAC.01386.
    PubMed     Abstract available


    December 2019
  34. KOBRAS CM, Piepenbreier H, Emenegger J, Sim A, et al
    BceAB-type antibiotic resistance transporters appear to act by target protection of cell wall synthesis.
    Antimicrob Agents Chemother. 2019 Dec 23. pii: AAC.02241.
    PubMed     Abstract available


  35. DEMCZUK W, Martin I, Sawatzky P, Allen V, et al
    Equations to predict antimicrobial minimum inhibitory concentrations in Neisseria gonorrhoeae using molecular antimicrobial resistance determinants.
    Antimicrob Agents Chemother. 2019 Dec 23. pii: AAC.02005.
    PubMed     Abstract available


  36. QIN T
    Reply to Edelstein, "Azithromycin Phenotypic versus Clinical Resistance".
    Antimicrob Agents Chemother. 2019;64.
    PubMed    


  37. EDELSTEIN PH
    Azithromycin Phenotypic versus Clinical Resistance.
    Antimicrob Agents Chemother. 2019;64.
    PubMed    


  38. ASLAM S, Schooley RT
    What's Old Is New Again: Bacteriophage Therapy in the 21st Century.
    Antimicrob Agents Chemother. 2019;64.
    PubMed     Abstract available


  39. ROSE WE, Bienvenida AM, Xiong YQ, Chambers HF, et al
    Ability of Bicarbonate Supplementation to Sensitize Selected Methicillin-Resistant Staphylococcus aureus (MRSA) Strains to beta-Lactam Antibiotics in an Ex Vivo Simulated Endocardial Vegetation Model.
    Antimicrob Agents Chemother. 2019 Dec 16. pii: AAC.02072.
    PubMed     Abstract available


  40. AOKI S, Nakase K, Nakaminami H, Wajima T, et al
    Transferable multidrug resistance plasmid carrying a novel macrolides-clindamycin resistance gene erm(50) in Cutibacterium acnes.
    Antimicrob Agents Chemother. 2019 Dec 16. pii: AAC.01810.
    PubMed     Abstract available


  41. AGUILERA-ALONSO D, Escosa-Garcia L, Saavedra-Lozano J, Cercenado E, et al
    Carbapenem-Resistant Gram-Negative Infections in Children.
    Antimicrob Agents Chemother. 2019 Dec 16. pii: AAC.02183.
    PubMed     Abstract available


  42. MULLANE EM, Avery LM, Nicolau DP
    Comparative evaluation of the in vitro activities of WCK 5222 (cefepime/zidebactam) and combination antibiotic therapies against carbapenem-resistant Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2019 Dec 16. pii: AAC.01669.
    PubMed     Abstract available


  43. TSOLAKI V, Mantzarlis K, Mpakalis A, Malli E, et al
    Ceftazidime-avibactam to treat life-threatening infections from carbapenem resistant pathogens in critically ill mechanically ventilated patients.
    Antimicrob Agents Chemother. 2019 Dec 9. pii: AAC.02320.
    PubMed     Abstract available


    November 2019
  44. RECIO R, Mancheno M, Viedma E, Villa J, et al
    Predictors of Mortality in Bloodstream Infections Caused by Pseudomonas aeruginosa: Impact of Antimicrobial Resistance and Bacterial Virulence.
    Antimicrob Agents Chemother. 2019 Nov 25. pii: AAC.01759.
    PubMed     Abstract available


  45. ALBAC S, Labrousse D, Hayez D, Anzala N, et al
    Activity of different anti-staphylococcal therapies, alone or combined, in a rat model of methicillin-resistant Staphylococcus epidermidis osteitis without implant.
    Antimicrob Agents Chemother. 2019 Nov 18. pii: AAC.01865.
    PubMed     Abstract available


  46. GHOSH D, Veeraraghavan B, Elangovan R, Vivekanandan P, et al
    Antibiotic resistance and epigenetics: more to it than meets the eye.
    Antimicrob Agents Chemother. 2019 Nov 18. pii: AAC.02225.
    PubMed     Abstract available


  47. FRAILE-RIBOT P, Zamorano L, Orellana R, Barrio-Tofino ED, et al
    Activity of imipenem/relebactam against a large collection of Pseudomonas aeruginosa clinical isolates and isogenic beta-lactam resistant mutants.
    Antimicrob Agents Chemother. 2019 Nov 18. pii: AAC.02165.
    PubMed     Abstract available


  48. CHEN M, Zhang C, Zhang X, Chen M, et al
    Meningococcal quinolone resistance originated from several commensal Neisseria species.
    Antimicrob Agents Chemother. 2019 Nov 18. pii: AAC.01494.
    PubMed     Abstract available


  49. HONDA H, Sato T, Shinagawa M, Fukushima Y, et al
    In vitro Derivation of Fluoroquinolone-resistant Mutants from Multiple Lineages of Haemophilus influenzae and Identification of Mutations Associated with Fluoroquinolone Resistance.
    Antimicrob Agents Chemother. 2019 Nov 18. pii: AAC.01500.
    PubMed     Abstract available


  50. WATSON A, Sauve K, Cassino C, Schuch R, et al
    Exebacase demonstrates in vitro synergy with a broad range of antibiotics against both methicillin-resistant and methicillin-susceptible Staphylococcus aureus.
    Antimicrob Agents Chemother. 2019 Nov 11. pii: AAC.01885.
    PubMed     Abstract available


  51. CASTANHEIRA M, Doyle TB, Kantro V, Mendes RE, et al
    Meropenem-Vaborbactam Activity against Carbapenem-Resistant Enterobacterales Isolates Collected in U.S. Hospitals During 2016-2018.
    Antimicrob Agents Chemother. 2019 Nov 11. pii: AAC.01951.
    PubMed     Abstract available


  52. THALSO-MADSEN I, Torrubia FR, Xu L, Petersen A, et al
    The Sle1 Cell Wall Amidase is essential for beta-Lactam Resistance in Community Acquired Methicillin Resistant Staphylococcus aureus USA300.
    Antimicrob Agents Chemother. 2019 Nov 4. pii: AAC.01931.
    PubMed     Abstract available


  53. KAYE KS, Patel T, Drusano G
    Is Daptomycin plus Ceftaroline the Way To Go for Methicillin-Resistant Staphylococcus aureus Bacteremia?
    Antimicrob Agents Chemother. 2019;63.
    PubMed    


    October 2019
  54. LOOSE M, Link I, Naber KG, Wagenlehner FME, et al
    Carbapenem-containing combination antibiotic therapy against carbapenem-resistant uropathogenic Enterobacteriaceae.
    Antimicrob Agents Chemother. 2019 Oct 21. pii: AAC.01839.
    PubMed     Abstract available


  55. IOVLEVA A, Mettus RT, McElheny CL, Griffifth MP, et al
    High-level carbapenem resistance triggered by ertapenem therapy in OXA-232-producing Raoultella ornithinolytica.
    Antimicrob Agents Chemother. 2019 Oct 21. pii: AAC.01335.
    PubMed     Abstract available


  56. YADAV R, Bergen PJ, Rogers KE, Kirkpatrick CMJ, et al
    Meropenem-tobramycin combination regimens combat carbapenem-resistant Pseudomonas aeruginosa in the hollow-fiber infection model simulating augmented renal clearance in critically ill patients.
    Antimicrob Agents Chemother. 2019 Oct 21. pii: AAC.01679.
    PubMed     Abstract available


  57. CEBALLOS S, Kim C, Qian Y, Mobashery S, et al
    Susceptibility of methicillin-resistant Staphylococcus aureus to five quinazolinone antibacterials.
    Antimicrob Agents Chemother. 2019 Oct 14. pii: AAC.01344.
    PubMed     Abstract available


  58. GUITOR AK, Raphenya AR, Klunk J, Kuch M, et al
    Capturing the Resistome: A targeted capture method to reveal antibiotic resistance determinants in metagenomes.
    Antimicrob Agents Chemother. 2019 Oct 14. pii: AAC.01324.
    PubMed     Abstract available


  59. CLANCY CJ, Nguyen MH
    Estimating the size of the United States market for new antibiotics with activity against carbapenem-resistant Enterobacteriaceae.
    Antimicrob Agents Chemother. 2019 Oct 7. pii: AAC.01733.
    PubMed     Abstract available


    September 2019
  60. LOPES AA, Yoshii Y, Yamada S, Nagakura M, et al
    Roles of lytic transglycosylases in biofilm formation and beta-lactam resistance in methicillin-resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 2019 Sep 30. pii: AAC.01277.
    PubMed     Abstract available


  61. YU X, Zheng B, Zhang J, Xu H, et al
    Comprehensive Genome Analysis of Carbapenem-Resistant Raoultella spp. strains, an Emerging Multidrug-Resistant Bacteria in Hospitals.
    Antimicrob Agents Chemother. 2019 Sep 30. pii: AAC.01367.
    PubMed     Abstract available


  62. SIMON MS, Sfeir MM, Calfee DP, Satlin MJ, et al
    Cost-effectiveness of ceftazidime-avibactam for treatment of carbapenem-resistant Enterobacteriaceae bacteremia and pneumonia.
    Antimicrob Agents Chemother. 2019 Sep 23. pii: AAC.00897.
    PubMed     Abstract available


  63. WATKINS RR, Holubar M, David MZ
    Antimicrobial resistance in methicillin-resistant Staphylococcus aureus to newer antimicrobial agents.
    Antimicrob Agents Chemother. 2019 Sep 16. pii: AAC.01216.
    PubMed     Abstract available


  64. KAWALEK A, Modrzejewska M, Zieniuk B, Bartosik AA, et al
    Interaction of ArmZ with the DNA-binding domain of MexZ induces expression of mexXY multidrug efflux pump genes and antimicrobial resistance in Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2019 Sep 16. pii: AAC.01199.
    PubMed     Abstract available


  65. RODRIGUES M, McBride SW, Hullahalli K, Palmer KL, et al
    Conjugative delivery of CRISPR-Cas9 for the selective depletion of antibiotic-resistant enterococci.
    Antimicrob Agents Chemother. 2019 Sep 16. pii: AAC.01454.
    PubMed     Abstract available


  66. WEBB HE, Tagg KA, Chen JC, Kim J, et al
    Novel quinolone resistance determinant, qepA8, in Shigella flexneri isolated in the United States, 2016.
    Antimicrob Agents Chemother. 2019 Sep 16. pii: AAC.01458.
    PubMed     Abstract available


  67. KIM D, Hong JS, Yoon EJ, Lee H, et al
    Toxic shock syndrome toxin 1-producing methicillin-resistant Staphylococcus aureus of clonal complex 5, the New York/Japan epidemic clone, causing a high early mortality rate in patients with bloodstream infections.
    Antimicrob Agents Chemother. 2019 Sep 9. pii: AAC.01362.
    PubMed     Abstract available


  68. YUI ETO K, Firth N, Davis AM, Kwong SM, et al
    Evolution of a 72-kb cointegrant, conjugative multiresistance plasmid from early community-associated methicillin-resistant Staphylococcus aureus isolates.
    Antimicrob Agents Chemother. 2019 Sep 9. pii: AAC.01560.
    PubMed     Abstract available


  69. LABORDA P, Alcalde-Rico M, Blanco P, Martinez JL, et al
    Novel inducers of the expression of multidrug efflux pumps that trigger Pseudomonas aeruginosa transient antibiotic resistance.
    Antimicrob Agents Chemother. 2019 Sep 9. pii: AAC.01095.
    PubMed     Abstract available


    August 2019
  70. HAN JH, Lapp Z, Bushman F, Lautenbach E, et al
    Whole Genome Sequencing to Identify Drivers of Carbapenem-Resistant Klebsiella pneumoniae Transmission Within and Between Regional Long-Term Acute Care Hospitals.
    Antimicrob Agents Chemother. 2019 Aug 26. pii: AAC.01622.
    PubMed     Abstract available


  71. FELDGARDEN M, Brover V, Haft DH, Prasad AB, et al
    Validating the NCBI AMRFinder Tool and Resistance Gene Database Using Antimicrobial Resistance Genotype-Phenotype Correlations in a Collection of NARMS Isolates.
    Antimicrob Agents Chemother. 2019 Aug 19. pii: AAC.00483.
    PubMed     Abstract available


  72. JIA X, Ren H, Nie X, Li Y, et al
    Antibiotic resistance and azithromycin resistance mechanism of Legionella pneumophila serogroup 1 in China.
    Antimicrob Agents Chemother. 2019 Aug 12. pii: AAC.00768.
    PubMed     Abstract available


  73. MARIMUTHU K, Ng OT, Cherng BPZ, Fong RKC, et al
    Antecedent Carbapenem Exposure as a Risk Factor for Non-Carbapenemase-Producing Carbapenem-Resistant Enterobacteriaceae (NCPCRE) and Carbapenemase-Producing Enterobacteriaceae (CPE).
    Antimicrob Agents Chemother. 2019 Aug 5. pii: AAC.00845.
    PubMed     Abstract available


  74. BOLARD A, Schniederjans M, Haussler S, Triponney P, et al
    Production of norspermidine contributes to aminoglycoside resistance in pmrAB mutants of Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2019 Aug 5. pii: AAC.01044.
    PubMed     Abstract available


  75. VAZQUEZ-UCHA JC, Martinez-Guitian M, Maneiro M, Conde-Perez K, et al
    Therapeutic efficacy of LN-1-255 in combination with imipenem in severe infection caused by carbapenem-resistant Acinetobacter baumannii.
    Antimicrob Agents Chemother. 2019 Aug 5. pii: AAC.01092.
    PubMed     Abstract available


  76. WILLIAMSON DA, Fairley CK, Howden BP, Chen MY, et al
    Trends and risk factors for antimicrobial-resistant Neisseria gonorrhoeae, Melbourne, Australia, 2007 - 2018.
    Antimicrob Agents Chemother. 2019 Aug 5. pii: AAC.01221.
    PubMed     Abstract available


  77. WRIGHT WF, Bejou N, Shields RK, Marr K, et al
    Amphotericin B Induction with Voriconazole Consolidation as Salvage Therapy for FKS-Associated Echinocandin Resistance in Candida glabrata Septic Arthritis and Osteomyelitis.
    Antimicrob Agents Chemother. 2019;63.
    PubMed     Abstract available


    July 2019
  78. KARAU MJ, Schmidt-Malan SM, Yan Q, Greenwood-Quaintance KE, et al
    Exebacase in Addition to Daptomycin is More Active than Daptomycin or Exebacase Alone in Methicillin-Resistant Staphylococcus aureus Osteomyelitis in Rats.
    Antimicrob Agents Chemother. 2019 Jul 29. pii: AAC.01235.
    PubMed     Abstract available


  79. XU Q, Chen T, Yan B, Zhang L, et al
    Dual role of gnaA in antibiotic resistance and virulence in Acinetobacter baumannii.
    Antimicrob Agents Chemother. 2019 Jul 29. pii: AAC.00694.
    PubMed     Abstract available


  80. G C B, Sahukhal GS, Elasri MO
    Role of the msaABCR operon in cell wall biosynthesis, autolysis, integrity, and antibiotic resistance in Staphylococcus aureus.
    Antimicrob Agents Chemother. 2019 Jul 15. pii: AAC.00680.
    PubMed     Abstract available


  81. AHMED MN, Porse A, Abdelsamad A, Sommer M, et al
    Lack of the major multifunctional catalase KatA in P.aeruginosa accelerates evolution of antibiotic resistance in ciprofloxacin-treated biofilms.
    Antimicrob Agents Chemother. 2019 Jul 15. pii: AAC.00766.
    PubMed     Abstract available


  82. DONG N, Sun Q, Huang Y, Shu L, et al
    Evolution of carbapenem-resistant serotype K1 hypervirulent Klebsiella pneumoniae by acquisition of bla VIM-1-bearing plasmid.
    Antimicrob Agents Chemother. 2019 Jul 15. pii: AAC.01056.
    PubMed     Abstract available


  83. DAHESH S, Wong B, Nizet V, Sakoulas G, et al
    Treatment of Multidrug-Resistant Vancomycin-Resistant Enterococcus faecium Hardware-Associated Vertebral Osteomyelitis with Oritavancin plus Ampicillin.
    Antimicrob Agents Chemother. 2019;63.
    PubMed     Abstract available


  84. CANVER MC, Satlin MJ, Westblade LF, Kreiswirth BN, et al
    Activity of imipenem-relebactam and comparator agents against genetically characterized isolates of carbapenem-resistant Enterobacteriaceae.
    Antimicrob Agents Chemother. 2019 Jul 1. pii: AAC.00672.
    PubMed     Abstract available


    June 2019
  85. YAMASHITA Y, Nagaoka K, Kimura H, Suzuki M, et al
    Efficacy of azithromycin in a mouse pneumonia model against hospital-acquired methicillin-resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 2019 Jun 24. pii: AAC.00149.
    PubMed     Abstract available


  86. PAULSHUS E, Thorell K, Guzman-Otazo J, Joffre E, et al
    Repeated isolation of ESBL positive Escherichia coli ST648 and ST131 from community wastewater - are sewage systems important sources of emerging clones of antibiotic resistant bacteria?
    Antimicrob Agents Chemother. 2019 Jun 24. pii: AAC.00823.
    PubMed     Abstract available


  87. LAM SW, Athans V
    Clinical and Microbiological Outcomes in Obese Patients Receiving Colistin for Carbapenem-Resistant Gram-negative Bloodstream Infection.
    Antimicrob Agents Chemother. 2019 Jun 24. pii: AAC.00531.
    PubMed     Abstract available


  88. NAKANO S, Fujisawa T, Ito Y, Chang B, et al
    Penicillin-binding protein typing, antibiotic resistance gene identification and molecular phylogenetic analysis of meropenem-resistant Streptococcus pneumoniae serotype 19A-CC3111 strains in Japan.
    Antimicrob Agents Chemother. 2019 Jun 24. pii: AAC.00711.
    PubMed     Abstract available


  89. LEE H, Boyle-Vavra S, Ren J, Jarusiewicz J, et al
    Identification of small molecules exhibiting oxacillin synergy through a novel assay for inhibition of vraTSR expression in methicillin resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 2019 Jun 17. pii: AAC.02593.
    PubMed     Abstract available


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    Antibiotic resistance plasmids cointegrated into a megaplasmid harbouring the blaOXA-427 carbapenemase gene.
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    Investigation of multiple resistance mechanisms in voriconazole resistant Aspergillus flavus clinical isolates from a chest hospital surveillance in Delhi, India.
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    Aspergillus fumigatus Afssn3-Afssn8 Pair Reverse regulates Azole Resistance by Conferring Extracellular Polysaccharide, Sphingolipid Pathway Intermediates and Efflux Pumps to Biofilm.
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  361. YU SJ, Chang YL, Chen YL
    Deletion of ADA2 increases antifungal drug susceptibility and virulence in Candida glabrata.
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  363. BHATTACHARYA S, Fries BC
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  364. VILCHEZE C, Kim J, Jacobs WR Jr
    Vitamin C potentiates the killing of Mycobacterium tuberculosis by the first-line tuberculosis drugs isoniazid and rifampicin in mice.
    Antimicrob Agents Chemother. 2018 Jan 3. pii: AAC.02165.
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    December 2017
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    Topical antibiotic use co-selects for the carriage of mobile genetic elements conferring resistance to unrelated antimicrobials in Staphylococcus aureus.
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    Mutations in Genes Encoding Penicillin-Binding Proteins and Efflux Pumps Play a Role in beta-Lactam Resistance in Helicobacter cinaedi.
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    Role of smeU1VWU2X Operon in the Alleviation of Oxidative Stresses and the Occurrence of Sulfamethoxazole/trimethoprim-resistant Mutants in Stenotrophomonas maltophilia.
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    Limited Effect of Later-generation Fluoroquinolones in the Treatment of Ofloxacin-resistant and Moxifloxacin-susceptible Multidrug-resistant Tuberculosis.
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    The comparative in vitro activity of relebactam, imipenem and the combination of the two, plus six comparator antimicrobial agents against 432 strains of anaerobic organisms including imipenem-resistant strains.
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    Outcomes of vancomycin plus a beta-lactam versus vancomycin only for the treatment of methicillin-resistant Staphylococcus aureus bacteremia.
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    Mutations in gene fusA1 as a novel mechanism of aminoglycoside resistance in clinical strains of Pseudomonas aeruginosa.
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  384. CHANDRA J, Ghannoum MA
    CD101, a Novel Echinocandin Possesses Potent Anti-biofilm Activity Against Early and Mature Candida albicans Biofilms.
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    Evaluation of Oritavancin Dosing Strategies against Vancomycin-Resistant Enterococcus faecium Isolates with or without Reduced Susceptibility to Daptomycin in an in vitro Pharmacokinetic/Pharmacodynamic Model.
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    Metabolic Mitigation of Staphylococcus aureus Vancomycin Intermediate-Level Susceptibility.
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    Detection of Mycobacterium tuberculosis pncA mutations by the NIPRO GenoscholarPZA-TB II as compared to conventional sequencing.
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  395. SAPUTO S, Faustoferri RC, Quivey RG Jr
    Vitamin D compounds are bactericidal against Streptococcus mutans and target the bacitracin-associated efflux system.
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    The gastrointestinal tract is a major source of echinocandin drug resistance in a murine model of Candida glabrata colonization and systemic dissemination.
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    Co-location of the multiresistance gene cfr and the fosfomycin resistance gene fosD on a novel plasmid in Staphylococcus arlettae from chicken farm.
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    Antiviral Activity of Bictegravir and Cabotegravir Against Integrase Inhibitor Resistant SIVmac239 and HIV-1.
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    AGAR-BASED SCREENING FOR AZOLE RESISTANCE IN ASPERGILLUS FUMIGATUS USING VIPcheck: A SINGLE CENTRE EVALUATION.
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    Chemical genomic interaction profiling reveals determinants of intrinsic antibiotic resistance in Mycobacterium tuberculosis.
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    Evolution of antibiotic resistance without antibiotic exposure.
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  420. HURST-HESS K, Rudra P, Ghosh P
    Mycobacterium abscessus WhiB7 regulates a species -specific repertoire of genes to confer extreme antibiotic resistance.
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    Immunodeficiency and Intermittent Dosing Promote Acquired Rifamycin Monoresistance in Murine Tuberculosis.
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    When Good Bugs Go Bad: Epidemiology and Antimicrobial Resistance Profiles of Corynebacterium striatum, an Emerging Multidrug Resistant, Opportunistic Pathogen.
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    Induction of mitochondrial ROS production by itraconazole, terbinafine and amphotericin B as a mode of action against Aspergillus fumigatus.
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    In Vitro Interactions of Echinocandins with Triazoles Against Multidrug-Resistant Candida auris.
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  426. VALENTINE-KING MA, Brown MB
    Antibacterial Resistance in Ureaplasma species and Mycoplasma hominis Isolates from Urine Cultures in College-aged Females.
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    Comparison of Cytomegalovirus Terminase Gene Mutations Selected after Exposure to Three Distinct Inhibitor Compounds.
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  430. CHEUNG YY, Hui M
    Effects of Echinocandins in combination with Nikkomycin Z against invasive Candida albicans bloodstream isolates and the fks mutants.
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    Both 14-day hybrid and bismuth quadruple therapies cure most patients with Helicobacter pylori infection in populations with moderate antibiotic resistance: a randomized controlled trial.
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    Candida albicans Swi/Snf and Mediator Complexes Differentially Regulate Mrr1-induced MDR1 Expression and Fluconazole Resistance.
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    Drug Susceptibility and Replicative Capacity of Multi-Drug Resistant Recombinant Human Cytomegalovirus Harboring Mutations in UL56 and UL54 Genes.
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    Identification of Plasmid-Mediated Quinolone Resistance in Salmonella Isolated from Swine Ceca and Retail Pork Chops in the United States.
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    July 2017
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    In vitro drug susceptibility of bedaquiline, delamanid, linezolid, clofazimine, moxifloxacin, and gatifloxacin against extensively drug -resistant tuberculosis from Beijing, China.
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    Tandem amplification of SCCmec can drive high level methicillin resistance in MRSA.
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    Evaluation of Combination Drug Therapy for Treatment of Antibiotic Resistant Inhalation Anthrax in a Murine Model.
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    Characterization of a large antibiotic resistance plasmid found in enteropathogenic Escherichia coli strain B171 and its relatedness to plasmids of diverse E. coli and Shigella.
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    In Vitro Antibiotic Susceptibilities of Francisella tularensis by Broth Micro-Dilution Following CLSI Methods.
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    A novel 6-benzyl ether benzoxaborole is active against Mycobacterium tuberculosis in vitro.
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    Meropenem-Vaborbactam Tested against Contemporary Gram-Negative Isolates Collected Worldwide During 2014, Including Carbapenem-Resistant, KPC-Producing, Multidrug-Resistant, and Extensively Drug-Resistant Enterobacteriaceae.
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    beta-Lactam Antibiotics with a High Affinity for PBP2 Act Synergistically with the FtsZ-Targeting Agent TXA707 against Methicillin-Resistant Staphylococcus aureus.
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    Ceftazidime-Avibactam and Aztreonam an interesting strategy to Overcome beta-Lactam Resistance Conferred by Metallo-beta-Lactamases in Enterobacteriaceae and Pseudomonas aeruginosa.
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    PA3225 is a transcriptional repressor of antibiotic resistance mechanisms in Pseudomonas aeruginosa.
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    Molecular Characterization of Escherichia coli Isolates Carrying mcr-1, fosA3, and Extended-Spectrum-beta-Lactamase Genes from Food Samples in China.
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    Characterizing the Antimicrobial Activity of N(2),N(4)-Disubstituted Quinazoline-2,4-Diamines toward Multidrug-Resistant Acinetobacter baumannii.
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    A Case-Control Study of Molecular Epidemiology in Relation to Azithromycin Resistance in Neisseria gonorrhoeae Isolates Collected in Amsterdam, the Netherlands, between 2008 and 2015.
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    ERG11 gene mutations and MDR1 up-regulation confer pan-azole-resistance in Candida tropicalis causing disseminated candidiasis while on posaconazole prophylaxis in an acute lymphoblastic leukemia patient.
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    In Vitro Cross-Resistance Profiles of Rilpivirine, Dapivirine and MIV-150: NNRTI Microbicides in Clinical Development for the Prevention of HIV-1 Infection.
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    New aspects of the interplay between penicillin binding proteins, murM and the two component system CiaRH of penicillin-resistant Streptococcus pneumoniae serotype 19A isolates from Hungary.
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    MCR-1.6, a New MCR Variant Carried by an IncP Plasmid in a Colistin-Resistant Salmonella enterica Serovar Typhimurium Isolate from a Healthy Individual.
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    Evolutionary origin of the staphylococcal cassette chromosome mec (SCCmec).
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    High-Level Resistance of Staphylococcus aureus to beta-Lactam Antibiotics Mediated by Penicillin-Binding Protein 4 (PBP4).
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    A Clostridium difficile Lineage Endemic to Costa Rican Hospitals Is Multidrug Resistant by Acquisition of Chromosomal Mutations and Novel Mobile Genetic Elements.
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    A Whole-Genome Sequencing Approach To Study Cefoxitin-Resistant Salmonella enterica Serovar Heidelberg Isolates from Various Sources.
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    Phenotypic and Molecular Antimicrobial Susceptibility of Helicobacter pylori.
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    Nasal Methicillin-Resistant Staphylococcus aureus (MRSA) PCR Testing Reduces the Duration of MRSA-Targeted Therapy in Patients with Suspected MRSA Pneumonia.
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  549. HARTL R, Kerschner H, Lepuschitz S, Ruppitsch W, et al
    Detection of the mcr-1 Gene in a Multidrug-Resistant Escherichia coli Isolate from an Austrian Patient.
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    Evolution of the Sterol Biosynthetic Pathway of Pythium insidiosum and Related Oomycetes Contributes to Antifungal Drug Resistance.
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    In Vitro Activity of Ceftolozane-Tazobactam against Multidrug-Resistant Nonfermenting Gram-Negative Bacilli Isolated from Patients with Cystic Fibrosis.
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    Determinants of Antibacterial Spectrum and Resistance Potential of the Elongation Factor G Inhibitor Argyrin B in Key Gram-Negative Pathogens.
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    Resistance to Thiacetazone Derivatives Active against Mycobacterium abscessus Involves Mutations in the MmpL5 Transcriptional Repressor MAB_4384.
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  555. MARTIN-GUTIERREZ G, Rodriguez-Martinez JM, Pascual A, Rodriguez-Beltran J, et al
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    Antimicrobial Activity of Ceftazidime-Avibactam against Gram-Negative Bacteria Isolated from Patients Hospitalized with Pneumonia in U.S. Medical Centers, 2011 to 2015.
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    March 2017
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    Antibiotic Effects on Methicillin Resistant Staphylococcus aureus Cytoplasmic Peptidoglycan Intermediate Levels; Evidence for Potential Metabolite Level Regulatory Loops.
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    Occurrence of acquired 16s methyltransferase mediated aminoglycoside resistance in clinical isolates of enterobacteriaceae within a tertiary referral hospital of northeast India.
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  562. MANGAT CS, Bekal S, Irwin RJ, Mulvey MR, et al
    A novel hybrid plasmid carrying multiple antimicrobial resistance and virulence genes in Salmonella Dublin.
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  563. MOYA B, Barcelo IM, Bhagwat S, Patel M, et al
    WCK 5107 (Zidebactam) & WCK 5153: Novel inhibitors of PBP2 showing potent "beta-lactam enhancer" activity against Pseudomonas aeruginosa, including multidrug-resistant metallo-beta-lactamase-producing high-risk clones.
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  564. PAUL S, Diekema D, Moye-Rowley WS
    Contributions of both ATP-binding cassette transporter and Cyp51A proteins are essential for azole resistance in Aspergillus fumigatus.
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  565. GARCIA-DE-LA-MARIA C, Xiong YQ, Pericas JM, Armero Y, et al
    Impact of High-Level Daptomycin-Resistance in Streptococcus mitis group on Virulence and Survivability during Daptomycin Treatment in Experimental Infective Endocarditis.
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  566. MILHEIRICO C, de Lencastre H, Tomasz A
    Full-Genome Sequencing Identifies in the Genetic Background Several Determinants That Modulate the Resistance Phenotype in Methicillin-Resistant Staphylococcus aureus Strains Carrying the Novel mecC Gene.
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  567. DORTET L, Girlich D, Virlouvet AL, Poirel L, et al
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    High Incidence of Escherichia coli Strains Coharboring mcr-1 and blaNDM from Chickens.
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    PER-8, a Novel Extended-Spectrum beta-Lactamase PER Variant, from an Acinetobacter baumannii Clinical Isolate in Nepal.
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    Low Frequency of Ceftazidime-Avibactam Resistance among Enterobacteriaceae Isolates Carrying blaKPC Collected in U.S. Hospitals from 2012 to 2015.
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  573. VARGHESE FS, Rausalu K, Hakanen M, Saul S, et al
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    Various Sequence Types of Escherichia coli Isolates Coharboring blaNDM-5 and mcr-1 Genes from a Commercial Swine Farm in China.
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    In Vitro Activities of MCB3681 and Eight Comparators against Clostridium difficile Isolates with Known Ribotypes and Diverse Geographical Spread.
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    Molecular confirmation of the relationship between Candida guilliermondii Fks1p naturally occurring amino acid substitutions and its intrinsic reduced echinocandin susceptibility.
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    The Emerging Candida auris: Characterization of Growth Phenotype, Virulence Factors, Antifungal Activity, and Effect of SCY-078, a Novel Glucan Synthesis Inhibitor, on Growth Morphology and Biofilm Formation.
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    Carbapenemase-Producing Enterobacteriaceae in Swine Production in the United States: Impact and Opportunities.
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  602. KAMATH D, Gregory ST, O'Connor M
    The Loop 2 Region of Ribosomal Protein uS5 Influences Spectinomycin Sensitivity, Translational Fidelity, and Ribosome Biogenesis.
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    Using In Vitro Dynamic Models To Evaluate Fluoroquinolone Activity against Emergence of Resistant Salmonella enterica Serovar Typhimurium.
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    January 2017
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    Effects of tedizolid phosphate on survival outcomes and suppression of production of staphylococcal toxins in a rabbit model of MRSA necrotizing pneumonia.
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    Some synonymous and non-synonymous gyrA mutations in Mycobacterium tuberculosis lead to systematic false-resistance results to fluoroquinolones with the Hain GenoType MTBDRsl assays.
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  612. GELDART K, Kaznessis YN
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    A Novel Phosphodiesterase of the GdpP Family Modulates Cyclic di-AMP Levels in Response to Cell Membrane Stress in Daptomycin-Resistant Enterococci.
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    December 2016
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    November 2016
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    De Novo Emergence of Genetically Resistant Mutants of Mycobacterium tuberculosis from the Persistence Phase Cells formed against Antituberculosis Drugs In Vitro.
    Antimicrob Agents Chemother. 2016 Nov 28. pii: AAC.01343.
    PubMed     Abstract available


  633. PENROSE KJ, Wallis CL, Brumme CJ, Hamanishi KA, et al
    Frequent Cross-Resistance to Dapivirine in HIV-1 Subtype C-Infected Individuals on Failing First-Line Antiretroviral Therapy in South Africa.
    Antimicrob Agents Chemother. 2016 Nov 28. pii: AAC.01805.
    PubMed     Abstract available


  634. BORDALLO-CARDONA MA, Escribano P, Gomez G de la Pedrosa E, Marcos-Zambrano LJ, et al
    In vitro exposure to increasing micafungin concentrations easily promotes echinocandin resistance in Candida glabrata isolates.
    Antimicrob Agents Chemother. 2016 Nov 21. pii: AAC.01542.
    PubMed     Abstract available


  635. PRIGENT G, Ait-Ammar N, Levesque E, Fekkar A, et al
    Echinocandin resistance in Candida spp. isolated from liver transplant recipients.
    Antimicrob Agents Chemother. 2016 Nov 14. pii: AAC.01229.
    PubMed     Abstract available


  636. SINGH M, Matsuo M, Sasaki T, Morimoto Y, et al
    In Vitro Tolerance of A Drug-Naive Staphylococcus aureus FDA209P towards Vancomycin.
    Antimicrob Agents Chemother. 2016 Nov 14. pii: AAC.01154.
    PubMed     Abstract available


  637. RUDRAMURTHY SM, Seyedmousavi S, Dhaliwal M, Chakrabarti A, et al
    Pharmacodynamics of voriconazole against wild-type and azole-resistant Aspergillus flavus isolates in a non-neutropenic murine model of disseminated aspergillosis.
    Antimicrob Agents Chemother. 2016 Nov 7. pii: AAC.01491.
    PubMed     Abstract available


  638. REIS DE SA LF, Toledo FT, Goncalves AC, Sousa BA, et al
    Synthetic organotellurium compounds sensitize drug resistant Candida albicans clinical isolates to fluconazole.
    Antimicrob Agents Chemother. 2016 Nov 7. pii: AAC.01231.
    PubMed     Abstract available


    October 2016
  639. WEI X, Chen P, Gao R, Li Y, et al
    Screening and characterization of the non-cyp51A mutation Afcox10 conferring azole resistance in Aspergillus fumigatus.
    Antimicrob Agents Chemother. 2016 Oct 31. pii: AAC.02101.
    PubMed     Abstract available


  640. STRAUSS C, Hu Y, Coates A, Perreten V, et al
    A novel erm(44) gene variant from a human Staphylococcus saprophyticus confers resistance to macrolides, lincosamides but not streptogramins.
    Antimicrob Agents Chemother. 2016 Oct 31. pii: AAC.01655.
    PubMed     Abstract available


  641. ESPINEL-INGROFF A, Arendrup M, Canton E, Cordoba S, et al
    A multi-center study of method-dependent epidemiological cutoff values (ECVs) for resistance detection in Candida spp. and Aspergillus spp. to amphotericin B and echinocandins for the Etest agar diffusion method.
    Antimicrob Agents Chemother. 2016 Oct 31. pii: AAC.01792.
    PubMed     Abstract available


  642. FAKHIM H, Emami S, Vaezi A, Hashemi SM, et al
    In Vitro Activities of Novel Azole Compounds (ATTAF-1 and ATTAF-2) Against Fluconazole-Susceptible and -Resistant Isolates of Candida species.
    Antimicrob Agents Chemother. 2016 Oct 24. pii: AAC.01106.
    PubMed     Abstract available


  643. SUWUNNAKORN S, Wakabayashi H, Rustchenko E
    Chromosome 5 of human pathogen Candida albicans carries multiple genes for negative control of caspofungin and anidulafungin susceptibility.
    Antimicrob Agents Chemother. 2016 Oct 10. pii: AAC.01888.
    PubMed     Abstract available


  644. HAYS C, Louis M, Plainvert C, Dmytruk N, et al
    Changing epidemiology of Group B Streptococcus susceptibility to fluoroquinolones and aminoglycosides in France.
    Antimicrob Agents Chemother. 2016 Oct 10. pii: AAC.01374.
    PubMed     Abstract available


    September 2016
  645. LI Y, Wang Y, Zhang Z, Gao H, et al
    Association between embB Codon 306 Mutations, Phenotypic Resistance Profiles and Genotypic Characterization in Clinical Mycobacterium tuberculosis Isolates from Hebei, China.
    Antimicrob Agents Chemother. 2016 Sep 26. pii: AAC.00532.
    PubMed     Abstract available


  646. CUI L, Wang Y, Lv Y, Wang S, et al
    Nationwide Surveillance of Novel Oxazolidinone Resistance Gene optrA in Enterococcus spp. Isolates in China from 2004-2014.
    Antimicrob Agents Chemother. 2016 Sep 19. pii: AAC.01256.
    PubMed     Abstract available


  647. TSIANG M, Jones GS, Goldsmith J, Mulato A, et al
    Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile.
    Antimicrob Agents Chemother. 2016 Sep 19. pii: AAC.01474.
    PubMed     Abstract available


  648. AMANO M, Salcedo-Gomez PM, Zhao R, Yedidi RS, et al
    A Modified P1 Moiety Enhances in vitro Antiviral Activity against Various Multi-Drug-Resistant HIV-1 Variants and in vitro CNS Penetration Properties of a Novel Nonpeptidic Protease Inhibitor, GRL-10413.
    Antimicrob Agents Chemother. 2016 Sep 12. pii: AAC.01428.
    PubMed     Abstract available


    August 2016
  649. ABASTABAR M, Rahimi N, Meis JF, Aslani N, et al
    Potent Activities of Novel Imidazoles (lanoconazole and luliconazole) Against a Collection of Azole Resistant and Susceptible Aspergillus fumigatus strains.
    Antimicrob Agents Chemother. 2016 Aug 29. pii: AAC.01193.
    PubMed     Abstract available


  650. ZHAO Y, Nagasaki Y, Kordalewska M, Press EG, et al
    Rapid detection of FKS-associated echinocandin resistance in Candida glabrata.
    Antimicrob Agents Chemother. 2016 Aug 22. pii: AAC.01574.
    PubMed     Abstract available


  651. DIEP BA, Le VT, Visram ZC, Rouha H, et al
    Improved protection in a rabbit model of CA-MRSA necrotizing pneumonia upon neutralization of leukocidins in addition to alpha-hemolysin.
    Antimicrob Agents Chemother. 2016 Aug 15. pii: AAC.01213.
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  652. CHUANG YM, Dutta NK, Hung CF, Wu TC, et al
    The stringent response factors PPX1 and PPK2 play an important role in Mycobacterium tuberculosis metabolism, biofilm formation, and sensitivity to isoniazid in vivo.
    Antimicrob Agents Chemother. 2016 Aug 15. pii: AAC.01139.
    PubMed     Abstract available


  653. FOO CS, Lechartier B, Kolly GS, Boy-Rottger S, et al
    Characterization of DprE1-mediated benzothiazinone resistance in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2016 Aug 15. pii: AAC.01523.
    PubMed     Abstract available


  654. NIKONENKO BV, Kornienko A, Majorov K, Ivanov P, et al
    In vitro activity of 3-triazenoindoles against Mycobacterium tuberculosis and Mycobacterium avium.
    Antimicrob Agents Chemother. 2016 Aug 8. pii: AAC.00998.
    PubMed     Abstract available


  655. HO PL, Liu MC, Chow KH, Tse CW, et al
    Emergence of ileS2-carrying, multidrug-resistant plasmids in Staphylococcus lugdunensis.
    Antimicrob Agents Chemother. 2016 Aug 8. pii: AAC.00948.
    PubMed     Abstract available


  656. PABST B, Pitts B, Lauchnor E, Stewart PS, et al
    Gel-entrapped Staphylococcus aureus as Models of Biofilm Infection Exhibit Growth in Dense Aggregates, Oxygen Limitation, Antibiotic Tolerance, and Heterogeneous Gene Expression.
    Antimicrob Agents Chemother. 2016 Aug 8. pii: AAC.01336.
    PubMed     Abstract available


  657. GU W, Guo D, Zhang L, Xu D, et al
    Synergistic Effect of Azoles and Fluoxetine against Resistant Candida albicans Attributed to Attenuating Fungal Virulence.
    Antimicrob Agents Chemother. 2016 Aug 8. pii: AAC.03046.
    PubMed     Abstract available


  658. WHALEY SG, Tsao S, Weber S, Zhang Q, et al
    The RTA3 gene, encoding a putative lipid translocase, influences the susceptibility of Candida albicans to fluconazole.
    Antimicrob Agents Chemother. 2016 Aug 1. pii: AAC.00732.
    PubMed     Abstract available


  659. WAN TW, Hung WC, Tsai JC, Lin YT, et al
    Novel structure of Enterococcus faecium-originated ermB positive Tn1546-like in Staphylococcus aureus.
    Antimicrob Agents Chemother. 2016 Aug 1. pii: AAC.01096.
    PubMed     Abstract available


  660. LOCKE JB, Almaguer AL, Zuill DE, Bartizal K, et al
    Characterization of in vitro resistance development to the novel echinocandin, CD101, in Candida species.
    Antimicrob Agents Chemother. 2016 Aug 1. pii: AAC.00620.
    PubMed     Abstract available


    July 2016
  661. HUANG K, Zhang Q, Song Y, Zhang Z, et al
    Characterization of spectinomycin resistance in Streptococcus suis: two novel insights into the drug-resistance formation and dissemination mechanism.
    Antimicrob Agents Chemother. 2016 Jul 25. pii: AAC.01157.
    PubMed     Abstract available


  662. MARTINEZ ZS, Castro E, Seong CS, Ceron MR, et al
    Fullerene Derivatives Strongly Inhibit HIV-1 Replication by Affecting Virus Maturation without Impairing Protease Activity.
    Antimicrob Agents Chemother. 2016 Jul 18. pii: AAC.00341.
    PubMed     Abstract available


  663. CHEN Y, Lu Z, Zhao J, Zou Z, et al
    Epidemiology and Molecular Characterizations of Azole Resistance in Clinical and Environmental Aspergillus fumigatus from China.
    Antimicrob Agents Chemother. 2016 Jul 18. pii: AAC.01005.
    PubMed     Abstract available


  664. BHATTACHARYA S, Sobel JD, White TC
    A Combination fluorescent assay demonstrates increased in Efflux Pump Activity as a resistance mechanism in Azole-Resistant Vaginal Candida albicans.
    Antimicrob Agents Chemother. 2016 Jul 18. pii: AAC.01252.
    PubMed     Abstract available


  665. CHONG J, Quach C, Blanchard AC, Poliquin PG, et al
    Molecular epidemiology of vancomycin-intermediate heteroresistant Staphylococcus epidermidis outbreak in the neonatal intensive care unit.
    Antimicrob Agents Chemother. 2016 Jul 11. pii: AAC.00726.
    PubMed     Abstract available


  666. BURNHAM JP, Burnham CA, Warren DK, Kollef MH, et al
    IMPACT OF TIME TO APPROPRIATE THERAPY ON MORTALITY IN PATIENTS WITH VANCOMYCIN INTERMEDIATE STAPHYLOCOCCUS AUREUS INFECTION.
    Antimicrob Agents Chemother. 2016 Jul 11. pii: AAC.00925.
    PubMed     Abstract available


  667. JONES JC, Marathe BM, Lerner C, Kreis L, et al
    A novel endonuclease inhibitor exhibits broad-spectrum anti-influenza activity in vitro.
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  668. LEONARDELLI F, Macedo D, Dudiuk C, Cabeza MS, et al
    Aspergillus fumigatus intrinsic fluconazole resistance is due to the naturally occurring T301I substitution in Cyp51Ap.
    Antimicrob Agents Chemother. 2016 Jul 5. pii: AAC.00905.
    PubMed     Abstract available


    May 2016
  669. LEPAK AJ, Andes DR
    In vivo Pharmacodynamic Target Assessment of Delafloxacin against Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumoniae in the Murine Lung Infection Model.
    Antimicrob Agents Chemother. 2016 May 23. pii: AAC.00647.
    PubMed     Abstract available


  670. CHIEN JY, Chien ST, Chiu WY, Yu CJ, et al
    Moxifloxacin Improves Treatment Outcomes in Patients with Ofloxacin-resistant Multidrug-resistant Tuberculosis.
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    PubMed     Abstract available


  671. BERGLUND B, Claesson C, Nilsson LE, Hanberger H, et al
    High prevalence of heterogeneously glycopeptide intermediate coagulase-negative staphylococci in sternal wounds.
    Antimicrob Agents Chemother. 2016 May 23. pii: AAC.00217.
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  672. CHEN H, Li C, Zemlicka J, Gentry BG, et al
    Potency and Stereoselectivity of Cyclopropavir Triphosphate Action on Human Cytomegalovirus DNA Polymerase.
    Antimicrob Agents Chemother. 2016 May 2. pii: AAC.00449.
    PubMed     Abstract available


  673. LINGARAJU S, Rigouts L, Gupta A, Lee J, et al
    Geographic differences in the contribution of ubiA mutations to high-level Ethambutol Resistance in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2016 May 2. pii: AAC.03002.
    PubMed     Abstract available


    April 2016
  674. GEORGHIOU SB, Seifert M, Catanzaro D, Garfein RS, et al
    Frequency and Distribution of Tuberculosis Resistance-Associated Mutations between Mumbai, Moldova, and Eastern Cape.
    Antimicrob Agents Chemother. 2016 Apr 18. pii: AAC.00222.
    PubMed     Abstract available


  675. NOWICKA-SANS B, Protack T, Lin Z, Li Z, et al
    BMS-955176: Identification and Characterization of a Second-Generation HIV-1 Maturation Inhibitor with Improved Potency, Anti-viral Spectrum and Gag Polymorphic Coverage.
    Antimicrob Agents Chemother. 2016 Apr 18. pii: AAC.02560.
    PubMed     Abstract available


  676. CHOU S, Ercolani RJ, Lanier ER
    Novel Cytomegalovirus UL54 DNA Polymerase Gene Mutations Selected in Vitro that Confer Brincidofovir Resistance.
    Antimicrob Agents Chemother. 2016 Apr 4. pii: AAC.00214.
    PubMed     Abstract available


    March 2016
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    DfrA-thyA double deletion in para-aminosalicylic acid resistant Mycobacterium tuberculosis Beijing strains.
    Antimicrob Agents Chemother. 2016 Mar 28. pii: AAC.00253.
    PubMed     Abstract available


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