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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 44 articles:
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Single Articles


    October 2022
  1. NYE TM, Tukenmez H, Singh P, Flores-Mireles AL, et al
    Ring-fused 2-pyridones effective against multidrug-resistant Gram-positive pathogens and synergistic with standard-of-care antibiotics.
    Proc Natl Acad Sci U S A. 2022;119:e2210912119.
    PubMed     Abstract available


  2. LI L, Chai Y, Peng W, Li D, et al
    Structural and inhibitor sensitivity analysis of influenza B-like viral neuraminidases derived from Asiatic toad and spiny eel.
    Proc Natl Acad Sci U S A. 2022;119:e2210724119.
    PubMed     Abstract available


  3. LI HZ, Yang K, Liao H, Lassen SB, et al
    Active antibiotic resistome in soils unraveled by single-cell isotope probing and targeted metagenomics.
    Proc Natl Acad Sci U S A. 2022;119:e2201473119.
    PubMed     Abstract available


    September 2022
  4. DAS SG, Krug J
    Unpredictable repeatability in molecular evolution.
    Proc Natl Acad Sci U S A. 2022;119:e2209373119.
    PubMed     Abstract available


  5. HUANG KJ, Pantua H, Diao J, Skippington E, et al
    Deletion of a previously uncharacterized lipoprotein lirL confers resistance to an inhibitor of type II signal peptidase in Acinetobacter baumannii.
    Proc Natl Acad Sci U S A. 2022;119:e2123117119.
    PubMed     Abstract available


  6. WONG JLC, David S, Sanchez-Garrido J, Woo JZ, et al
    Recurrent emergence of Klebsiella pneumoniae carbapenem resistance mediated by an inhibitory ompK36 mRNA secondary structure.
    Proc Natl Acad Sci U S A. 2022;119:e2203593119.
    PubMed     Abstract available


  7. ZARNOWSKI R, Sanchez H, Jaromin A, Zarnowska UJ, et al
    A common vesicle proteome drives fungal biofilm development.
    Proc Natl Acad Sci U S A. 2022;119:e2211424119.
    PubMed     Abstract available


  8. ROGAWSKI MCQUADE ET, Brennhofer SA, Elwood SE, McMurry TL, et al
    Frequency of bystander exposure to antibiotics for enteropathogenic bacteria among young children in low-resource settings.
    Proc Natl Acad Sci U S A. 2022;119:e2208972119.
    PubMed     Abstract available


  9. WILLIS JA, Cheburkanov V, Chen S, Soares JM, et al
    Breaking down antibiotic resistance in methicillin-resistant Staphylococcus aureus: Combining antimicrobial photodynamic and antibiotic treatments.
    Proc Natl Acad Sci U S A. 2022;119:e2208378119.
    PubMed     Abstract available


  10. TOBA S, Sato A, Kawai M, Taoda Y, et al
    Identification of cap-dependent endonuclease inhibitors with broad-spectrum activity against bunyaviruses.
    Proc Natl Acad Sci U S A. 2022;119:e2206104119.
    PubMed     Abstract available


    July 2022
  11. SINGH AK, De Wijngaert B, Bijnens M, Uyttersprot K, et al
    Cryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine.
    Proc Natl Acad Sci U S A. 2022;119:e2203660119.
    PubMed     Abstract available


  12. FAIT A, Seif Y, Mikkelsen K, Poudel S, et al
    Adaptive laboratory evolution and independent component analysis disentangle complex vancomycin adaptation trajectories.
    Proc Natl Acad Sci U S A. 2022;119:e2118262119.
    PubMed     Abstract available


  13. RASOULY A, Nudler E
    The very hungry bactericidal antibiotics.
    Proc Natl Acad Sci U S A. 2022;119:e2208035119.
    PubMed    


    May 2022
  14. NEWBURY A, Dawson B, Klumper U, Hesse E, et al
    Fitness effects of plasmids shape the structure of bacteria-plasmid interaction networks.
    Proc Natl Acad Sci U S A. 2022;119:e2118361119.
    PubMed     Abstract available


  15. LIAKOPOULOS A, Aulin LBS, Buffoni M, Fragkiskou E, et al
    Allele-specific collateral and fitness effects determine the dynamics of fluoroquinolone resistance evolution.
    Proc Natl Acad Sci U S A. 2022;119:e2121768119.
    PubMed     Abstract available


    April 2022
  16. HERNANDO-AMADO S, Laborda P, Valverde JR, Martinez JL, et al
    Mutational background influences P. aeruginosa ciprofloxacin resistance evolution but preserves collateral sensitivity robustness.
    Proc Natl Acad Sci U S A. 2022;119:e2109370119.
    PubMed     Abstract available


  17. LAUGHLIN ZT, Nandi S, Dey D, Zelinskaya N, et al
    50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA.
    Proc Natl Acad Sci U S A. 2022;119:e2120352119.
    PubMed     Abstract available


  18. GEORGE NL, Schilmiller AL, Orlando BJ
    Conformational snapshots of the bacitracin sensing and resistance transporter BceAB.
    Proc Natl Acad Sci U S A. 2022;119:e2123268119.
    PubMed     Abstract available


    March 2022
  19. ZHANG Q, Wang R, Wang M, Liu C, et al
    Re-sensitization of mcr carrying multidrug resistant bacteria to colistin by silver.
    Proc Natl Acad Sci U S A. 2022;119:e2119417119.
    PubMed     Abstract available


    February 2022
  20. VASAN AK, Haloi N, Ulrich RJ, Metcalf ME, et al
    Role of internal loop dynamics in antibiotic permeability of outer membrane porins.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  21. KARITA Y, Limmer DT, Hallatschek O
    Scale-dependent tipping points of bacterial colonization resistance.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    November 2021
  22. MARTIN MJ, Corey BW, Sannio F, Hall LR, et al
    Anatomy of an extensively drug-resistant Klebsiella pneumoniae outbreak in Tuscany, Italy.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  23. REITHUBER E, Wixe T, Ludwig KC, Muller A, et al
    THCz: Small molecules with antimicrobial activity that block cell wall lipid intermediates.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  24. KONIG G, Sokkar P, Pryk N, Heinrich S, et al
    Rational prioritization strategy allows the design of macrolide derivatives that overcome antibiotic resistance.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    October 2021
  25. DAN L, Li Y, Chen S, Liu J, et al
    A rapidly reversible mutation generates subclonal genetic diversity and unstable drug resistance.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  26. LI J, Sae Her A, Traaseth NJ
    Asymmetric protonation of glutamate residues drives a preferred transport pathway in EmrE.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    September 2021
  27. ADKINS-JABLONSKY SJ, Clark CM, Papoulis SE, Kuhl MD, et al
    Market forces determine the distribution of a leaky function in a simple microbial community.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    August 2021
  28. LIM J, Lee JJ, Lee SK, Kim S, et al
    Phosphoenolpyruvate depletion mediates both growth arrest and drug tolerance of Mycobacterium tuberculosis in hypoxia.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  29. CHAHAL J, Gebert LFR, Camargo C, MacRae IJ, et al
    miR-122-based therapies select for three distinct resistance mechanisms based on alterations in RNA structure.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  30. OTTONI C, Boric D, Cheronet O, Sparacello V, et al
    Tracking the transition to agriculture in Southern Europe through ancient DNA analysis of dental calculus.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  31. DIMITRIU T, Matthews AC, Buckling A
    Increased copy number couples the evolution of plasmid horizontal transmission and plasmid-encoded antibiotic resistance.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    July 2021
  32. GRASS LM, Wollenhaupt J, Barthel T, Parfentev I, et al
    Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  33. ZHANG J, Zhao X, Cappiello JR, Yang Y, et al
    Identification of simple arylfluorosulfates as potent agents against resistant bacteria.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    June 2021
  34. ARAGAW WW, Lee BM, Yang X, Zimmerman MD, et al
    Potency boost of a Mycobacterium tuberculosis dihydrofolate reductase inhibitor by multienzyme F420H2-dependent reduction.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  35. QIAN X, Gunturu S, Sun W, Cole JR, et al
    Long-read sequencing revealed cooccurrence, host range, and potential mobility of antibiotic resistome in cow feces.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    May 2021
  36. CHE Y, Yang Y, Xu X, Brinda K, et al
    Reply to Shaw: Challenges for enrichment analysis of AMR gene-bearing plasmids.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  37. SCHUBERT MG, Goodman DB, Wannier TM, Kaur D, et al
    High-throughput functional variant screens via in vivo production of single-stranded DNA.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    April 2021
  38. JO WK, Schadenhofer A, Habierski A, Kaiser FK, et al
    Reverse genetics systems for contemporary isolates of respiratory syncytial virus enable rapid evaluation of antibody escape mutants.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    March 2021
  39. ANGST DC, Tepekule B, Sun L, Bogos B, et al
    Comparing treatment strategies to reduce antibiotic resistance in an in vitro epidemiological setting.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    February 2021
  40. HUEMER M, Mairpady Shambat S, Bergada-Pijuan J, Soderholm S, et al
    Molecular reprogramming and phenotype switching in Staphylococcus aureus lead to high antibiotic persistence and affect therapy success.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  41. CHE Y, Yang Y, Xu X, Brinda K, et al
    Conjugative plasmids interact with insertion sequences to shape the horizontal transfer of antimicrobial resistance genes.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  42. CARD KJ, Thomas MD, Graves JL Jr, Barrick JE, et al
    Genomic evolution of antibiotic resistance is contingent on genetic background following a long-term experiment with Escherichia coli.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    January 2021
  43. GIRGIS HS, DuPai CD, Lund J, Reeder J, et al
    Single-molecule nanopore sequencing reveals extreme target copy number heterogeneity in arylomycin-resistant mutants.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  44. OLDENKAMP R, Schultsz C, Mancini E, Cappuccio A, et al
    Filling the gaps in the global prevalence map of clinical antimicrobial resistance.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


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