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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 34 articles:
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Single Articles


    May 2026
  1. WANG Y, Zhang Q, Wang Y, Chen Z, et al
    Reply to Huang and Dong: Circuit insights unlock translational potential of peripheral electroacupuncture for epilepsy.
    Proc Natl Acad Sci U S A. 2026;123:e2611095123.
    PubMed    


    March 2026
  2. ZHANG C, Hu L, Zhang H, Yang M, et al
    DIRAS2 modulates MAPK pathway-mediated ferroptosis to regulate excitation/inhibition balance and seizure susceptibility.
    Proc Natl Acad Sci U S A. 2026;123:e2516011123.
    PubMed     Abstract available


  3. WOLOSKER H, Liebl DJ
    A mitochondrial-neuroinflammation-D-serine connection in epilepsy.
    Proc Natl Acad Sci U S A. 2026;123:e2604050123.
    PubMed    


  4. WANG Y, Zhang Q, Wu S, Hu K, et al
    Electroacupuncture-based vagal stimulation attenuates epileptic seizures through a body-brain circuit.
    Proc Natl Acad Sci U S A. 2026;123:e2517600123.
    PubMed     Abstract available


  5. DONNEGER F, Zanin A, Besson J, Roussel D, et al
    Enhancing KCC2 function reduces interictal activity and prevents seizures in temporal lobe epilepsy.
    Proc Natl Acad Sci U S A. 2026;123:e2522722123.
    PubMed     Abstract available


  6. JIANG J, Zuo M, Zhao K, Ling Z, et al
    mtDNA leakage promotes neuron-glia crosstalk to induce epilepsy by cGAS-STING-driven neuroinflammation and serine metabolic reprogramming.
    Proc Natl Acad Sci U S A. 2026;123:e2522313123.
    PubMed     Abstract available


    February 2026
  7. LI M, Zhu Z, Li D, Wang J, et al
    CDKL5 modulates the plasticity of excitatory synapses via liquid-liquid phase separation.
    Proc Natl Acad Sci U S A. 2026;123:e2511123123.
    PubMed     Abstract available


    December 2025
  8. JIANG X, Cai Z, Gonsisko C, Worrell GA, et al
    Mapping epileptogenic brain using a unified spatial-temporal-spectral source imaging framework.
    Proc Natl Acad Sci U S A. 2025;122:e2510015122.
    PubMed     Abstract available


    August 2025
  9. JANG SS, Agranonik N, Huguenard JR
    Actions of the antiseizure drug carbamazepine in the thalamic reticular nucleus: Potential mechanism of aggravating absence seizures.
    Proc Natl Acad Sci U S A. 2025;122:e2500644122.
    PubMed     Abstract available


    July 2025
  10. BIZZOTTO S, Talukdar M, Stronge EA, Ramirez RB, et al
    Cell-type-informed genotyping of mosaic focal epilepsies reveals cell-autonomous and non-cell-autonomous disease-associated transcriptional programs.
    Proc Natl Acad Sci U S A. 2025;122:e2509622122.
    PubMed     Abstract available


  11. STASENKO A, Kaestner E, Schadler AJ, Reyes A, et al
    Dynamic neuroplasticity of language networks: The intersection of bilingualism and epilepsy.
    Proc Natl Acad Sci U S A. 2025;122:e2422742122.
    PubMed     Abstract available


    June 2025
  12. TABIKH M, Quetu T, Maillard L, Colnat-Coulbois S, et al
    Transcranial direct current stimulation neuromodulates intracranial cognitive evoked activity in humans.
    Proc Natl Acad Sci U S A. 2025;122:e2416541122.
    PubMed     Abstract available


    April 2025
  13. MULLER PM, Miron G, Holtkamp M, Meisel C, et al
    Critical dynamics predicts cognitive performance and provides a common framework for heterogeneous mechanisms impacting cognition.
    Proc Natl Acad Sci U S A. 2025;122:e2417117122.
    PubMed     Abstract available


  14. HYDER SK, Lazarini-Lopes W, Toib J, Williams G, et al
    Optogenetic stimulation of the dorsal striatum bidirectionally controls seizures.
    Proc Natl Acad Sci U S A. 2025;122:e2419178122.
    PubMed     Abstract available


    February 2025
  15. MAHER C, Tortolero L, Jun S, Cummins DD, et al
    Intracranial substrates of meditation-induced neuromodulation in the amygdala and hippocampus.
    Proc Natl Acad Sci U S A. 2025;122:e2409423122.
    PubMed     Abstract available


    December 2024
  16. RAMIREZ JG, Vanhoyland M, Ratan Murty NA, Decramer T, et al
    Intracortical recordings reveal the neuronal selectivity for bodies and body parts in the human visual cortex.
    Proc Natl Acad Sci U S A. 2024;121:e2408871121.
    PubMed     Abstract available


  17. KAN ASH, Kusay AS, Mohammadi NA, Lin SXN, et al
    Understanding paralogous epilepsy-associated GABA(A) receptor variants: Clinical implications, mechanisms, and potential pitfalls.
    Proc Natl Acad Sci U S A. 2024;121:e2413011121.
    PubMed     Abstract available


  18. CHOI JM, Acharya R, Cha HL, Lee KW, et al
    CB1R activates the epilepsy-associated protein Go to regulate neurotransmitter release and synaptic plasticity in the cerebellum.
    Proc Natl Acad Sci U S A. 2024;121:e2409773121.
    PubMed     Abstract available


  19. PATEL A, Pauzuolyte V, Ingham NJ, Leong YC, et al
    Rescue of cochlear vascular pathology prevents sensory hair cell loss in Norrie disease.
    Proc Natl Acad Sci U S A. 2024;121:e2322124121.
    PubMed     Abstract available


    October 2024
  20. WANG W, Williams DJ, Teoh JJ, Soundararajan D, et al
    Impaired axon initial segment structure and function in a model of ARHGEF9 developmental and epileptic encephalopathy.
    Proc Natl Acad Sci U S A. 2024;121:e2400709121.
    PubMed     Abstract available


    July 2024

  21. Correction for Veno et al., A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy.
    Proc Natl Acad Sci U S A. 2024;121:e2411972121.
    PubMed    


  22. DONG P, Bakhurin K, Li Y, Mikati MA, et al
    Attenuating midline thalamus bursting to mitigate absence epilepsy.
    Proc Natl Acad Sci U S A. 2024;121:e2403763121.
    PubMed     Abstract available


  23. ROBERT S, Granovetter MC, Patterson C, Behrmann M, et al
    Hemispheric functional organization, as revealed by naturalistic neuroimaging, in pediatric epilepsy patients with cortical resections.
    Proc Natl Acad Sci U S A. 2024;121:e2317458121.
    PubMed     Abstract available


    June 2024
  24. CAPITANO F, Kuchenbuch M, Lavigne J, Chaptoukaev H, et al
    Preictal dysfunctions of inhibitory interneurons paradoxically lead to their rebound hyperactivity and to low-voltage-fast onset seizures in Dravet syndrome.
    Proc Natl Acad Sci U S A. 2024;121:e2316364121.
    PubMed     Abstract available


    May 2024
  25. PARK J, Lee E, Kim CH, Ohk J, et al
    Mosaicism-independent mechanisms contribute to Pcdh19-related epilepsy and repetitive behaviors in Xenopus.
    Proc Natl Acad Sci U S A. 2024;121:e2321388121.
    PubMed     Abstract available


    April 2024
  26. XU N, Cao R, Chen SY, Gou XZ, et al
    Structural and functional reorganization of inhibitory synapses by activity-dependent cleavage of neuroligin-2.
    Proc Natl Acad Sci U S A. 2024;121:e2314541121.
    PubMed     Abstract available


  27. COSTANZA M, Ciotti A, Consonni A, Cipelletti B, et al
    CNS autoimmune response in the MAM/pilocarpine rat model of epileptogenic cortical malformation.
    Proc Natl Acad Sci U S A. 2024;121:e2319607121.
    PubMed     Abstract available


    February 2024
  28. ZITO A, Lee JT
    Variable expression of MECP2, CDKL5, and FMR1 in the human brain: Implications for gene restorative therapies.
    Proc Natl Acad Sci U S A. 2024;121:e2312757121.
    PubMed     Abstract available


  29. YANG YC, Wang GH, Chou P, Hsueh SW, et al
    Dynamic electrical synapses rewire brain networks for persistent oscillations and epileptogenesis.
    Proc Natl Acad Sci U S A. 2024;121:e2313042121.
    PubMed     Abstract available


    January 2024
  30. CLATOT J, Currin CB, Liang Q, Pipatpolkai T, et al
    A structurally precise mechanism links an epilepsy-associated KCNC2 potassium channel mutation to interneuron dysfunction.
    Proc Natl Acad Sci U S A. 2024;121:e2307776121.
    PubMed     Abstract available


    December 2023
  31. GULFO MC, Lebowitz JJ, Ramos C, Hwang DW, et al
    Dopamine D2 receptors in hilar mossy cells regulate excitatory transmission and hippocampal function.
    Proc Natl Acad Sci U S A. 2023;120:e2307509120.
    PubMed     Abstract available


    November 2023
  32. ZHONG X, Moresco JJ, Keller K, Lazaro DR, et al
    Essential requirement for IER3IP1 in B cell development.
    Proc Natl Acad Sci U S A. 2023;120:e2312810120.
    PubMed     Abstract available


    September 2023
  33. MOHAMED MS, Klann E
    Autism- and epilepsy-associated EEF1A2 mutations lead to translational dysfunction and altered actin bundling.
    Proc Natl Acad Sci U S A. 2023;120:e2307704120.
    PubMed     Abstract available


  34. ARAKI Y, Gerber EE, Rajkovich KE, Hong I, et al
    Mouse models of SYNGAP1-related intellectual disability.
    Proc Natl Acad Sci U S A. 2023;120:e2308891120.
    PubMed     Abstract available


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