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Ophthalmology

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Articles published in Invest Ophthalmol Vis Sci
Retrieve available abstracts of 1339 articles:
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April 2026

QUAGRAINE IM, Shi S, Cakir GB, Murray J, et al
"Look Versus See": Does Varying Fellow Eye Contrast Affect Perception of the Amblyopic Eye?
Invest Ophthalmol Vis Sci. 2026;67:6.
PubMed Abstract available

WYSOCKA A, Jaskiewicz-Rajewicz K, Wozniak J, Rydzanicz M, et al
"Eye-Conic" Spatial Transcriptomics Reveals the Layer-Specific Molecular Alterations in Corneas of Patients With Keratoconus.
Invest Ophthalmol Vis Sci. 2026;67:7.
PubMed Abstract available

XU Z, Zhou Y, Pang Y, He Y, et al
Effects of Monocular Perceptual Learning on Eye-Specific Cortical Activity in Residual Anisometropic Amblyopia: Evidence From EEG Asymmetry.
Invest Ophthalmol Vis Sci. 2026;67:8.
PubMed Abstract available

KOLZ C, Neul C, Hofmann U, Dressler JC, et al
Identification of Brimonidine as a Novel Substrate of Organic Cation Transporters OCT2 and MATE1 Expressed in Human Eye.
Invest Ophthalmol Vis Sci. 2026;67:4.
PubMed Abstract available

HSU YR, Gao CM, Chin WY, Miaw SC, et al
Cytomegalovirus-Specific T Cell Immunity and Clinical Associations in Patients With CMV Anterior Uveitis.
Invest Ophthalmol Vis Sci. 2026;67:5.
PubMed Abstract available

DU R, Yang E, Ayyala R, Du Y, et al
Hepatocyte Growth Factor Confers Trabecular Meshwork Stem Cell Resilience and Paracrine Protection of Trabecular Meshwork Cells in Glaucoma.
Invest Ophthalmol Vis Sci. 2026;67:1.
PubMed Abstract available

HAN F, Wang L, Wu J, Ma H, et al
PIM1 Inhibition Alleviates Aspergillus fumigatus Keratitis by Regulating DDX41-Mediated STING Signaling Pathway.
Invest Ophthalmol Vis Sci. 2026;67:2.
PubMed Abstract available

GIRKIN CA, Walker E, Gardiner SK, Hallaj S, et al
Glaucomatous Remodeling of the Lamina Cribrosa: Association With Visual Field Progression.
Invest Ophthalmol Vis Sci. 2026;67:3.
PubMed Abstract available

March 2026

OU L, Cui B, Zhou L, Liu K, et al
Neuropilin-2 Deficiency Promotes Mitochondrial Dysfunction and NAD(+)-Dependent Cellular Senescence in Retinal Degeneration.
Invest Ophthalmol Vis Sci. 2026;67:11.
PubMed Abstract available

CLERIN E, Yang Y, Pagan D, Achiedo S, et al
Combined Expression of hRdCVF and hRdCVFL Through AAV-Mediated Delivery for the Treatment of Retinitis Pigmentosa.
Invest Ophthalmol Vis Sci. 2026;67:2.
PubMed Abstract available

LEE BJ, Agarwal D, Huang JH, Ivanova A, et al
A Cross-Species Hydroquinone Model Replicates Smoking-Related Corneal Endothelial Oxidative Injury and Enables Therapeutic Screening of FGF10.
Invest Ophthalmol Vis Sci. 2026;67:12.
PubMed Abstract available

CAI M, Wang X, Sun S, Yuan Z, et al
Tannic Acid Achieves Rapid Scar-Free Corneal Healing by Chelating Excess Copper to Suppress Aberrant LOX-Mediated Fibrosis.
Invest Ophthalmol Vis Sci. 2026;67:13.
PubMed Abstract available

ZHAO Y, Wu J, Li C, Cheng Y, et al
Plasma Proteomic Dynamics Preceding Glaucoma Reveal a 15-Year Pre-Diagnostic Window: Causal Insights and Predictive Utility in 45,850 Participants.
Invest Ophthalmol Vis Sci. 2026;67:14.
PubMed Abstract available

CHEN C, Razavi R, Romano F, Niessen H, et al
Hyperspectral Imaging for the Classification and Analysis of Drusen in Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2026;67:10.
PubMed Abstract available

TRIPATHI R, Sinha NR, Sood S, Gupta S, et al
Myogenic Differentiation (MyoD) Gene Expression in Cornea and Role in Corneal Myofibroblast Dedifferentiation.
Invest Ophthalmol Vis Sci. 2026;67:7.
PubMed Abstract available

TAO S, Hu W, Hu Y, Cheng Q, et al
Sfrp2 in Microglia Inhibited S100a8-Mediated Neuroinflammation and Protected Neural Damage Following Retinal Ischemia-Reperfusion.
Invest Ophthalmol Vis Sci. 2026;67:8.
PubMed Abstract available

SUANNO G, Fonteyne P, De Micheli M, Bandello F, et al
The Impact of Aging and Sex on Corneal Nerve Density and Function.
Invest Ophthalmol Vis Sci. 2026;67:3.
PubMed Abstract available

FU M, Peng D, Xu Y, Zhang Y, et al
CL-EVLPs Promote Corneal Repair in a BAC-Induced Corneal Injury Model via Ocular Microenvironment Reconstruction.
Invest Ophthalmol Vis Sci. 2026;67:4.
PubMed Abstract available

CHEN TR, Zhou JX, Hou YR, Zhang YN, et al
Neddylation-Mediated hnRNPA2B1 Degradation Aggravates Retinal Endothelial Cell Dysfunction in Diabetic Retinopathy by Regulating miR-93-5p/VEGFA.
Invest Ophthalmol Vis Sci. 2026;67:5.
PubMed Abstract available

LIN X, Deng S, Li W, Vendra VPR, et al
betaA4-Crystallin Mutations Disrupt Structural Stability and Crystallin Interactions in Congenital Cataract Pathogenesis.
Invest Ophthalmol Vis Sci. 2026;67:29.
PubMed Abstract available

CHEN B, Xu Y, Xie S, Zhou X, et al
Identification of COL4A2 as a Biomarker of Extracellular Matrix Remodeling and Vascular Scaffold in Choroid for Myopia.
Invest Ophthalmol Vis Sci. 2026;67:31.
PubMed Abstract available

BLAIR NP, Leahy S, Matei N, Shahidi M, et al
Retinal Hypoxia: Relation to Blood Flow and Oxygen Metabolic Biomarkers.
Invest Ophthalmol Vis Sci. 2026;67:32.
PubMed Abstract available

GAZANCHIAN M, Nejad A, Crabb DP, Montesano G, et al
Archetypes of Binocular Visual Field Loss and Their Impact on Vision-Related Quality of Life in Glaucoma Patients.
Invest Ophthalmol Vis Sci. 2026;67:28.
PubMed Abstract available

LIN S, Tan WD, Robson AG, Arno G, et al
Characterizing a Unique Retinal Phenotype in INTS11-Associated Neurodevelopmental Disorder.
Invest Ophthalmol Vis Sci. 2026;67:21.
PubMed Abstract available

WILLIAMS G, Lee J, Zangirolani G, Reynaud J, et al
Optic Nerve Head Spatial Transcriptomic Change in Nonhuman Primate Early Experimental Glaucoma.
Invest Ophthalmol Vis Sci. 2026;67:22.
PubMed Abstract available

JASKIEWICZ-RAJEWICZ K, Wysocka A, Matuszewska-Mach E, Rzetecka N, et al
Common and Distinct Features in Serum Proteomic Profiles in Keratoconus, Post-Laser Vision Correction Ectasia, and Pellucid Marginal Degeneration.
Invest Ophthalmol Vis Sci. 2026;67:23.
PubMed Abstract available

MCLEOD DS, Bhutto IA, Messinger JD, Berlin A, et al
Choroidal Vascular Findings in a Case of Multifocal Geographic Atrophy: A Clinicopathologic Correlation.
Invest Ophthalmol Vis Sci. 2026;67:19.
PubMed Abstract available

KOLGE H, Ahmad Z, Singh S, Yu M, et al
Chitosan-Coated Silver-Vancomycin Nanoparticles for Treatment of Bacterial Endophthalmitis.
Invest Ophthalmol Vis Sci. 2026;67:20.
PubMed Abstract available

ATTAWAY CA, Brown TC, McCall MA, McGee AW, et al
Enhancing Experience-Dependent Plasticity Accelerates Vision Loss in a Murine Model of Retinitis Pigmentosa.
Invest Ophthalmol Vis Sci. 2026;67:15.
PubMed Abstract available

YOUNGBLOOD HA, Cai J, Sun J, Elsayed OA, et al
Pro-Homeostatic Effects of Estrogen on Intraocular Pressure and the Trabecular Meshwork.
Invest Ophthalmol Vis Sci. 2026;67:16.
PubMed Abstract available

BENOIT J, Adel Y, Lam K, Medina-Cornejo J, et al
Unraveling the Heritability of Ocular Rigidity and Myopia-Related Traits: A Siblings-Based Study.
Invest Ophthalmol Vis Sci. 2026;67:17.
PubMed Abstract available

SLENTER IJM, Smit AAG, Schipper BW, Broekhuizen-Stins MJ, et al
The In Vitro Antibacterial Effects of Genipin Against Pathogens Commonly Associated With Infected Ulcerative Keratitis: A Canine Preliminary Study.
Invest Ophthalmol Vis Sci. 2026;67:18.
PubMed Abstract available

IBUKUN F, Strauss RW, Rustam Z, Khan MJ, et al
Longitudinal Changes of Fundus Autofluorescence and Correlation With Visual Acuity in ABCA4-Associated Stargardt Disease.
Invest Ophthalmol Vis Sci. 2026;67:6.
PubMed Abstract available

LIU C, Liao X
On the Limited Predictive Value of Prior Myopia Progression: Methodological Considerations for Clinical Prediction.
Invest Ophthalmol Vis Sci. 2026;67:24.
PubMed

SASAMOTO Y, Suzuki K, Sato S, Lee CAA, et al
Essential Role of CD63 in Maintaining Corneal Epithelial Identity in the Human Limbus.
Invest Ophthalmol Vis Sci. 2026;67:25.
PubMed Abstract available

LEE DI, Kim SY, Ji YW, Yeo A, et al
Immune Regulatory Role of Parasympathetic Nervous System in Murine Corneal Allografts via Inhibition of Dendritic Cell Activation and T Cell Polarization.
Invest Ophthalmol Vis Sci. 2026;67:26.
PubMed Abstract available

ZHAO Y, Ma Y, Li Y, Jiang C, et al
Growth Trajectories During Early Childhood and Ocular Development in High-Risk Infants.
Invest Ophthalmol Vis Sci. 2026;67:27.
PubMed Abstract available

YAN C, Fu Q, Wang J, Fan Q, et al
An APE1 Redox Inhibitor Attenuates Pathological Retinal Vascularization by Suppressing FGF2 Angiogenic Signaling.
Invest Ophthalmol Vis Sci. 2026;67:47.
PubMed Abstract available

WANG L, Li H, Xiong L, Sun C, et al
Targeting CRBN With Thalidomide Suppresses Fibrosis After Glaucoma Drainage Surgery Through NF-kappaB Pathway Inhibition.
Invest Ophthalmol Vis Sci. 2026;67:48.
PubMed Abstract available

LI J, Zhang G, Li J, Liu R, et al
Nintedanib Eye Drops Inhibit Alkali Burn-Induced Corneal Neovascularization Via RAP1/MEK/ERK Signaling Pathway.
Invest Ophthalmol Vis Sci. 2026;67:44.
PubMed Abstract available

IBY J, Kreminger J, Stino H, Niederleithner M, et al
Retinal Characteristics in Eyes With Retinal Vein Occlusion Using Widefield Swept-Source Optical Coherence Tomography Angiography.
Invest Ophthalmol Vis Sci. 2026;67:45.
PubMed Abstract available

WANG CX, Wang J, Hormel TT, Hwang TS, et al
Volumetric and En Face Hyper-Reflective Henle Fiber Layer in Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2026;67:41.
PubMed Abstract available

WEN Y, Feng L, Xu S, Zhang T, et al
Targeted Ferroptosis Improves RPE Phagocytosis via MERTK/NFE2L2/HMOX1 Axis to Alleviate Retinitis Pigmentosa.
Invest Ophthalmol Vis Sci. 2026;67:42.
PubMed Abstract available

NODECKER KN, Romano F, Stettler I, Shah S, et al
Reduced Macular Pigment Optical Volume Is Linked to High-Risk OCT Biomarkers and Lower Contrast Sensitivity Function in iAMD.
Invest Ophthalmol Vis Sci. 2026;67:36.
PubMed Abstract available

CHEN CH, Lin CW, Wu SH, Yang ZW, et al
NOTCH3 Pathogenic Variant and Risk of Age-Related Macular Degeneration: Findings From the Taiwan Biobank and Small Vessel Disease Registry.
Invest Ophthalmol Vis Sci. 2026;67:37.
PubMed Abstract available

VERA-DIAZ FA, Kerber KL
Effect of Binocularity and Depth on Static and Dynamic Accommodation Responses in Young Children.
Invest Ophthalmol Vis Sci. 2026;67:38.
PubMed Abstract available

MENG Z, Zhang J, Luo Z, Ma J, et al
Biphasic Change in Retinal Arterial Hemodynamics Amidst Systematic Perfusion Decline With Increasing Degree of Myopia.
Invest Ophthalmol Vis Sci. 2026;67:39.
PubMed Abstract available

SHARMA A, Kizy S, Singh NK
Understanding the Molecular Basis of Pathological Retinal Angiogenesis: Roles of Lipids, Non-Coding RNAs, and Cellular Crosstalk.
Invest Ophthalmol Vis Sci. 2026;67:33.
PubMed Abstract available

CURCIO CA, Owsley C
The Science of Rod-Mediated Dark Adaptation, an Outcome Measure for Age-Related Macular Degeneration: The 2025 Proctor Medal Lecture.
Invest Ophthalmol Vis Sci. 2026;67:34.
PubMed Abstract available

PFAU M
Introducing Christine A. Curcio and Cynthia Owsley, the 2025 Recipients of the Proctor Medal.
Invest Ophthalmol Vis Sci. 2026;67:35.
PubMed Abstract available

FOSHE S, Shi S, Bell BA, Lee S, et al
A Remarkable Tale: Increased Retinal Fluorescence Following Application of Permanent Marker Ink to Mouse Tails.
Invest Ophthalmol Vis Sci. 2026;67:40.
PubMed Abstract available

MICHAUD C, Faurite C, Guenot J, Gallice M, et al
Perceptual Learning as a Rehabilitation Approach to Enhance Motion Processing in Maculopathy Patients.
Invest Ophthalmol Vis Sci. 2026;67:52.
PubMed Abstract available

LEE EJ, Kim H, Yoon J, Lee SJ, et al
Long-Term Clinical Course and Progression Patterns of Normal-Tension Glaucoma Following Disc Hemorrhage.
Invest Ophthalmol Vis Sci. 2026;67:53.
PubMed Abstract available

PU J, Gao L, Thomas TN, Goerdt L, et al
Choriocapillaris Flow Signal Deficits Are Associated With AMD Onset and Early Progression Over Three Years: ALSTAR2 Follow-Up.
Invest Ophthalmol Vis Sci. 2026;67:51.
PubMed Abstract available

AN Q, Qin X, Zhong L, Cui L, et al
Ocular Surface Microbiota-Derived Lipoteichoic Acid Promotes Dry Eye Disease by Inducing Corneal Inflammation.
Invest Ophthalmol Vis Sci. 2026;67:50.
PubMed Abstract available

LEE SH, Lee SJ, Yun YI, Koh A, et al
Interferon Regulatory Factor 3 as a Mediator and Therapeutic Target in Innate Immune-Driven Corneal Stromal Inflammation and Opacity.
Invest Ophthalmol Vis Sci. 2026;67:49.
PubMed Abstract available

TRINH M, Nguyen J, Lee M, Wang J, et al
Eccentricity-Dependent Reflectivity Rates-of-Change Across the Retina in Intermediate Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2026;67:62.
PubMed Abstract available

ZHANG X, Liu L, Li Y, Han S, et al
Neurovascular Coupling Disruption and Glymphatic Dysfunction Are Associated With Visual Impairment in Pediatric Monocular Anisometropic Amblyopia.
Invest Ophthalmol Vis Sci. 2026;67:63.
PubMed Abstract available

LIN H, Wu H, Liu C, Zhong Y, et al
Terahertz Photons Promote Corneal Injury Repair via Epithelial Proliferation, Migration, and Inflammation Reduction.
Invest Ophthalmol Vis Sci. 2026;67:56.
PubMed Abstract available

HAN Z, Guo H, Wang B, Zhu Y, et al
Acute Inflammation Drives Corneal Pathological Regeneration.
Invest Ophthalmol Vis Sci. 2026;67:58.
PubMed Abstract available

MACHANE D, Shaji MS, Borchman D, Jaeger V, et al
Meibum Lipid Saturation Related to Dry Eye, Age, and Sex Using Nuclear Magnetic Resonance Spectroscopy.
Invest Ophthalmol Vis Sci. 2026;67:60.
PubMed Abstract available

LIU Y, Siegfried CJ, Wu H, Shui YB, et al
Tissue-Specific Antioxidant Capacity in Primary Open-Angle Glaucoma Patients.
Invest Ophthalmol Vis Sci. 2026;67:55.
PubMed Abstract available

Erratum in: Inner Retina Changes in ABCA4-Related Retinopathy: Structure-Function Relationship.
Invest Ophthalmol Vis Sci. 2026;67:65.
PubMed

IGNATOVA I, Koskelainen A
Carbon Dioxide Euthanasia Selectively Affects Physiology of Murine Retinal Cells, Implicating Carbonic Anhydrase-Expressing Cell Populations.
Invest Ophthalmol Vis Sci. 2026;67:61.
PubMed Abstract available

LIN J, Lee PY, Tran KKN, Finkelstein DI, et al
Detailed Outer Retinal Assessment in Parkinson's Disease Using Directional OCT.
Invest Ophthalmol Vis Sci. 2026;67:59.
PubMed Abstract available

KINANE C, Panchal M, Tsoulfas P, Talla V, et al
AAV2-Retro-Mediated Gene Transfer Selectively Targets Outer Retinal Cells Following Intravitreal Injection.
Invest Ophthalmol Vis Sci. 2026;67:54.
PubMed Abstract available

February 2026

APPELBAUM T, Smith DA, Takahashi K, Sudharsan R, et al
Crosstalk Between R-Loops, RNA/DNA Modifications, and Cell Death Dynamics in Canine Models of Retinitis Pigmentosa.
Invest Ophthalmol Vis Sci. 2026;67:20.
PubMed Abstract available

YUAN J, Cui X, Yu-Wai-Man P, Xiao X, et al
Integrative Proteogenomic Analysis Identifies Genetically Supported Plasma Proteins, Metabolites, and Pathways in Glaucoma.
Invest Ophthalmol Vis Sci. 2026;67:21.
PubMed Abstract available

LI Q, Bao Q, Wei C, Xie Y, et al
AIF-1 Drives Corneal Neovascularization by Promoting Inflammatory Macrophage Activation via the MAPK and PI3K/AKT/mTOR Signaling Pathways.
Invest Ophthalmol Vis Sci. 2026;67:22.
PubMed Abstract available

QIAO Y, Zhao C, Yao S, Dou S, et al
Taurochenodeoxycholic Acid Activates Calcium Signaling to Protect Against Fuchs' Endothelial Corneal Dystrophy.
Invest Ophthalmol Vis Sci. 2026;67:16.
PubMed Abstract available

JONAS JB, Jonas RA, Bikbov MM, Kazakbaeva GM, et al
Ocular and General Determinants of Intraocular Pressure: The Two-Continent Eye Study.
Invest Ophthalmol Vis Sci. 2026;67:17.
PubMed Abstract available

LIN Y, Luo W, Zhu X, Yu J, et al
The Molecular Mechanisms and Therapeutic Potentials of Engrailed-1 in Fibrotic Scar Formation Post Glaucoma Filtration Surgery.
Invest Ophthalmol Vis Sci. 2026;67:18.
PubMed Abstract available

COBOS E, Catala-Mora J, Aguilera C, Biarnes M, et al
Genotype-Phenotype Correlations in ABCA4-Associated Retinopathy: Insights From a Spanish Cohort of 245 Patients.
Invest Ophthalmol Vis Sci. 2026;67:19.
PubMed Abstract available

MEHROTRA S, Jeanneret H, Perkumas K, Liu R, et al
Time-Dependent Glucocorticoid-Induced Transcriptomic Changes in Human Trabecular Meshwork and Schlemm's Canal Cells.
Invest Ophthalmol Vis Sci. 2026;67:13.
PubMed Abstract available

TAN S, Yang D, Yang Y, Hou J, et al
Motor Skill Deficits and Associated Factors in Childhood Intermittent Exotropia: A Cross-Sectional Study.
Invest Ophthalmol Vis Sci. 2026;67:14.
PubMed Abstract available

QI D, Ba M, Xuan S, Huang D, et al
beta-Adrenergic Signaling Contributes to Circadian and Lipid Dysregulation in Meibomian Glands During Chronic Psychological Stress.
Invest Ophthalmol Vis Sci. 2026;67:15.
PubMed Abstract available

SUTTER DA, Igelman A, Coyner AS, Stratis G, et al
Computational Vascular Development Model Explaining Incidence of Notch in Retinopathy of Prematurity With Ultra-Widefield Optical Coherence Tomography.
Invest Ophthalmol Vis Sci. 2026;67:10.
PubMed Abstract available

QUARTA A, Alhelaly M, Romano F, Soylu C, et al
High-Resolution OCT Profiling of Bruch's Membrane in Extensive Macular Atrophy With Pseudodrusen-Like Appearance and Geographic Atrophy.
Invest Ophthalmol Vis Sci. 2026;67:12.
PubMed Abstract available

BROEKEMA NM, Larsen IV, Griese C, Naruzawa ES, et al
The Use of Free-Living Amoeba in Treating Bacterial Infections: Thermotolerant Dictyostelids Are Avirulent and Do Not Cause Keratitis in Mice.
Invest Ophthalmol Vis Sci. 2026;67:7.
PubMed Abstract available

LESSIEUR EM, Saadane A, Du Y, Kiser J, et al
Theophylline Inhibits Capillary Degeneration in Early Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2026;67:8.
PubMed Abstract available

NAVNEET S, Rohrer B
CR2-fH, A Targeted Inhibitor of Alternative Complement Pathway Reduces Dry AMD-Like Phenotype in AMD Patient iPSC-derived RPE Cells.
Invest Ophthalmol Vis Sci. 2026;67:9.
PubMed Abstract available

HASSAN S, Stanley ST, Brandauer E, Hsu Y, et al
Profound Effect of Light on Cysts in X-Linked Retinoschisis.
Invest Ophthalmol Vis Sci. 2026;67:1.
PubMed Abstract available

KUMAR M, Karnam S, Maurya S, Nagireddy R, et al
Lipoxin B4 Mitigates TRPV4-Activated Muller Cell Gliosis During Ocular Hypertension.
Invest Ophthalmol Vis Sci. 2026;67:2.
PubMed Abstract available

NSOUR G, Misawa MAM, Adamuccio J, Goldsmith M, et al
Correction of Abnormal Head Position in Pediatric Nystagmus Using Yoked Low-Value Prism Glasses: A Retrospective Study.
Invest Ophthalmol Vis Sci. 2026;67:3.
PubMed Abstract available

XU J, Gao Y, Yu J, Xu Z, et al
Large-Scaled Proteomics Analysis for Glaucoma: Integrated Genetics, Multi-Omics, UK Biobank and Therapeutic Analysis.
Invest Ophthalmol Vis Sci. 2026;67:4.
PubMed Abstract available

OKRENT SMOLAR AL, Viswanath R, Bomze HM, Hao Y, et al
Pharmacological Depletion of Retinal Mononuclear Phagocytes Is Neuroprotective in a Mouse Model of Mitochondrial Optic Neuropathy.
Invest Ophthalmol Vis Sci. 2026;67:6.
PubMed Abstract available

RAI M, Choi K, Chan HH
Acute Ocular Hypertension Diminishes Flicker-Induced Enhancement in Retinal Blood Flow and Full-Field Electroretinogram in a Mouse Model.
Invest Ophthalmol Vis Sci. 2026;67:33.
PubMed Abstract available

ZHANG Y, Min D, Wang Y, Yu W, et al
MTG2 as a Causal and Druggable Target in Uveal Melanoma via Mitochondrial DNA Dynamics: Evidence From Functional Validation and DMSA Identification.
Invest Ophthalmol Vis Sci. 2026;67:30.
PubMed Abstract available

PAS JAAH, Kunzel SH, Ansari G, Pfau K, et al
Genetic Correlates of Phenotypic Variability in c.5882G>A p.(Gly1961Glu)-Associated Stargardt Disease.
Invest Ophthalmol Vis Sci. 2026;67:32.
PubMed Abstract available

HASEGAWA T, Iwai S, Ikeda HO, Miyaoka D, et al
Increased Gut Microbiota Diversity in Patients With Retinitis Pigmentosa and Implications for Disease Phenotypes and Progression.
Invest Ophthalmol Vis Sci. 2026;67:27.
PubMed Abstract available

SANZ E, Aivar MP, Tejedor J
Differences in Smooth Pursuit and Associated Saccades in Children With Two Common Types of Strabismus.
Invest Ophthalmol Vis Sci. 2026;67:28.
PubMed Abstract available

CHUANGSUWANICH T, Nongpiur ME, Braeu FA, Prasad SC, et al
AI to Identify Strain-Sensitive Regions of the Optic Nerve Head Linked to Functional Loss in Glaucoma.
Invest Ophthalmol Vis Sci. 2026;67:29.
PubMed Abstract available

DUNN M, Cull G, Reynaud J, Gardiner SK, et al
Microvascular Volume Loss Exceeds Nerve Fiber Layer but Not Neuroretinal Rim Tissue Loss During Progression of Nonhuman Primate Experimental Glaucoma.
Invest Ophthalmol Vis Sci. 2026;67:24.
PubMed Abstract available

MOUHAMMAD ZA, Tribble JR, Nicol A, Andreopoulou E, et al
Semaglutide Protects Retinal Ganglion Cells Against Rotenone-Induced Degeneration via Improved Glucose Metabolism.
Invest Ophthalmol Vis Sci. 2026;67:25.
PubMed Abstract available

KREBS AK, Diaz D, Sassani JW, Zagon IS, et al
Mitigation of Oxidative Stress Pathways in the Diabetic Cornea and Lacrimal Glands Contributes to the Rapid Reversal of Diabetic Dry Eye by Naltrexone.
Invest Ophthalmol Vis Sci. 2026;67:23.
PubMed Abstract available

MANDAL S, Sucharita S, Garg N, Priyadarshini SR, et al
Host Response and Pathogen Load in Acanthamoeba Keratitis: A Histopathological Analysis.
Invest Ophthalmol Vis Sci. 2026;67:36.
PubMed Abstract available

BAGGA DK, Padmanabhan AAG, Jayaraman D, Raghuram A, et al
Contrast Sensitivity and Low-Contrast Visual Acuity in Children With Low Vision.
Invest Ophthalmol Vis Sci. 2026;67:38.
PubMed Abstract available

KONTOH-TWUMASI R, Aliste A, Scheid A, Lax K, et al
Altered Carnitine Homeostasis Modulates Hyperosmolarity-Induced Mitochondrial Dysfunction and Lipotoxicity in Human Corneal Epithelial Cells.
Invest Ophthalmol Vis Sci. 2026;67:39.
PubMed Abstract available

WANG L, Yan H, Shen Y, Xin S, et al
The Intracellular C5a-mtC5aR1 Axis Promotes Necroptosis in Dry Eye Through DRP1-Mediated Mitochondrial Dysfunction.
Invest Ophthalmol Vis Sci. 2026;67:35.
PubMed Abstract available

TRINH M, Borrelli E, Reibaldi M, Foti C, et al
Inner Retinal Reflectivity Loss and Concurrent Thickening Predict Short-Term Conversion to Neovascular AMD.
Invest Ophthalmol Vis Sci. 2026;67:34.
PubMed Abstract available

HAMMER M, Geisweid L, Junker N, Wohlfart S, et al
In-Depth Analysis of the Intravitreal Biocompatibility of Polyethylene Glycol of Different Molecular Weight in an In Vivo Porcine Model.
Invest Ophthalmol Vis Sci. 2026;67:37.
PubMed Abstract available

GUEVARA MONTOYA PA, Carrillo Y, Verma S, You H, et al
Applied Anatomical and Morphological Characterization of the Ocular Surface of the African Spiny Mice: Acomys cahirinus.
Invest Ophthalmol Vis Sci. 2026;67:26.
PubMed Abstract available

Erratum in: Relative Myopic Defocus in the Superior Retina as an Indicator of Myopia Development in Children.
Invest Ophthalmol Vis Sci. 2026;67:11.
PubMed

CHENG XR, Meng ZY, Feng WT, Tang XL, et al
Ophthalmic Artery Morphology and Hemodynamics in Ocular Ischemic Syndrome: A Computational Fluid Dynamics and Particle Image Velocimetry Study.
Invest Ophthalmol Vis Sci. 2026;67:5.
PubMed Abstract available

YANG Y, Yan K, Tang Y, Liu Z, et al
AMPK Deficiency Induces Corneal Epithelial Barrier Dysfunction by Modulating Energy Homeostasis.
Invest Ophthalmol Vis Sci. 2026;67:47.
PubMed Abstract available

JAGGI U, Wang S, Hirose S, Arya D, et al
Macrophages From Latently Infected Mice Have Trained Immunity to HSV-1.
Invest Ophthalmol Vis Sci. 2026;67:49.
PubMed Abstract available

YANG Z, Yan Y, Deng Q, Gao Y, et al
YBX1 Modulated Corneal Neovascularization Induced by Alkali Burn via m5C-Dependent Regulation of the STAT3/HIF-1alpha/VEGFA Axis.
Invest Ophthalmol Vis Sci. 2026;67:42.
PubMed Abstract available

MESTRE C, Candy TR
The Impact of Simulated Anisometropia and Bilateral Defocus on Reflex Vergence Responses of Children and Adults.
Invest Ophthalmol Vis Sci. 2026;67:43.
PubMed Abstract available

STETTLER I, Romano F, Ding X, Garg I, et al
Optical Coherence Tomography Angiography Characterization of Vascular Alterations in Macular Telangiectasia Type 2.
Invest Ophthalmol Vis Sci. 2026;67:44.
PubMed Abstract available

LIN Y, Wang J, Zhang S, Xu T, et al
Histone Acetylation Landscape and the Role of HAT1 in Regulating Corneal Epithelial Wound Healing.
Invest Ophthalmol Vis Sci. 2026;67:45.
PubMed Abstract available

YU Y, Zhang Y, Tang Y, Ma L, et al
Advanced Glycation End-Products Contribute to Delayed Diabetic Corneal Epithelial Wound Healing via the TLR4 Signaling.
Invest Ophthalmol Vis Sci. 2026;67:40.
PubMed Abstract available

HUANG L, Liang W, Huma T, Clayton JM, et al
Ferroptosis: A Novel Mechanism in Diabetic Keratopathy.
Invest Ophthalmol Vis Sci. 2026;67:41.
PubMed Abstract available

CHEN Q, Wei Y, Wang L, Liang J, et al
Ly93 Inhibits Sphingomyelin Synthesis and Attenuates Inflammation and Injury in Dry Eye Conjunctival Organoids.
Invest Ophthalmol Vis Sci. 2026;67:58.
PubMed Abstract available

SHAH SV, Brant AR, Zhao CS, Wang SK, et al
P-Score Variability as a Function of Retinopathy of Prematurity Severity.
Invest Ophthalmol Vis Sci. 2026;67:59.
PubMed Abstract available

CHEN J, Davison CW, Ellis J, Blevins B, et al
CRISPR Base Editing Correction of TGFBI Mutations in Autosomal Dominant Corneal Dystrophies.
Invest Ophthalmol Vis Sci. 2026;67:60.
PubMed Abstract available

SUN Y, Cao D, Meng J, Wang L, et al
A Murine Model of HSV-1-Induced Corneal Endotheliitis: Primary Infection, Latency, and Recurrence.
Invest Ophthalmol Vis Sci. 2026;67:61.
PubMed Abstract available

Erratum in: Apicobasal Polarity Protein PARD3 Plays an Essential Role in Human Corneal Epithelial Cells.
Invest Ophthalmol Vis Sci. 2026;67:57.
PubMed

DE COSTER E, De Clerck K, De Clercq C, Li W, et al
Photodisruption of the Inner Limiting Membrane Promotes Retinal Engraftment of Stem-Cell Derived Retinal Ganglion Cells.
Invest Ophthalmol Vis Sci. 2026;67:56.
PubMed Abstract available

WALL K, Fritsch S, Vaisband M, Hasenauer J, et al
Near-Infrared Fluorescence Lifetime Imaging Microscopy Reveals Loss of RPE Cell Body Polarity in Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2026;67:55.
PubMed Abstract available

YU H, Zeng F, Qu J, Liu X, et al
METTL3 Potentiates Corneal Allograft Rejection via Increased Pro-Inflammatory Cytokine Production and Aerobic Glycolysis.
Invest Ophthalmol Vis Sci. 2026;67:48.
PubMed Abstract available

Erratum in: Abnormal Splicing in the Final Intron of PRX Results in Dominant Congenital Cataract Without Neurological Phenotype.
Invest Ophthalmol Vis Sci. 2026;67:52.
PubMed

January 2026

SINHA NR, Hofmann AC, Suleiman LA, Jeffrey MT, et al
Alterations in Mitochondrial DNA in Corneal Fibroblast and Myofibroblast Post Injury.
Invest Ophthalmol Vis Sci. 2026;67:36.
PubMed Abstract available

BEAULIEU WT, Repka MX, Pineles SL, Chandler DL, et al
Does Past Myopia Progression Predict Future Progression?
Invest Ophthalmol Vis Sci. 2026;67:38.
PubMed Abstract available

JAVIDJAM D, Moustardas P, Dashti A, Aberdam D, et al
Transcriptomic Analysis in a Model of Aniridia-Associated Keratopathy for Target Discovery and Evaluation of Duloxetine Therapy.
Invest Ophthalmol Vis Sci. 2026;67:37.
PubMed Abstract available

CHEUNG R, Trinh M, Duong A, Chen S, et al
Prognostic Ability of Automated RPE Sinuosity for Late AMD Supersedes Qualitative Outer Retinal Band Assessment.
Invest Ophthalmol Vis Sci. 2026;67:33.
PubMed Abstract available

SUBCZYNSKI WK, Mainali L, Collery RF, Pasenkiewicz-Gierula M, et al
Preventing Age-Related Nuclear Cataract Development - Is Cholesterol the Key?
Invest Ophthalmol Vis Sci. 2026;67:34.
PubMed Abstract available

FOROOZANDEH P, Kaplan N, Xu D, Qi X, et al
Losartan Alleviates Chemical Burn-Induced Limbal Stem Cell Deficiency: Repurposing a Venerable Anti-Hypertension Drug.
Invest Ophthalmol Vis Sci. 2026;67:35.
PubMed Abstract available

SUN X, Liang Y, Liang Y, Li W, et al
PRPF8 Mutation-Induced Defects in Human iPSC-Derived RPE Are Rescued by Adenine Base Editing.
Invest Ophthalmol Vis Sci. 2026;67:21.
PubMed Abstract available

BIRNER K, Mai J, Boryshchuk D, Frommlet F, et al
Exploring Trial Endpoints in Geographic Atrophy Based on Localized Functional Changes in Microperimetry and AI-Quantified OCT Biomarkers.
Invest Ophthalmol Vis Sci. 2026;67:22.
PubMed Abstract available

LIU S, Guan Z, Yang X, Li W, et al
Inhibition of Retinal AdoRA2a Activity Attenuates Myopia Progression.
Invest Ophthalmol Vis Sci. 2026;67:15.
PubMed Abstract available

LYU A, Mungalsingh MA, Silva AE, Khan S, et al
Transcranial Direct Current Stimulation Does Not Enhance Perceptual Learning of Chinese Character Reading in Adults With Macular Degeneration.
Invest Ophthalmol Vis Sci. 2026;67:16.
PubMed Abstract available

PANG J, Wei Z, Zhang Z, Xu X, et al
Genomic Landscape Reveals Correlation of Endosymbiont Ralstonia With Acanthamoeba Keratitis Severity.
Invest Ophthalmol Vis Sci. 2026;67:17.
PubMed Abstract available

ZHU J, Feng Y, Huang X, Zuo M, et al
Spatiotemporal Dynamics of Binocular Interaction in Anisometropic Amblyopia Revealed by Classification Image.
Invest Ophthalmol Vis Sci. 2026;67:18.
PubMed Abstract available

GE H, Zhang Y, Guo Q, Li Y, et al
CGRP/TSP1 Signaling Dampens Corneal Inflammation and Fibrosis by Targeting A2M During Corneal Stromal Wound Healing.
Invest Ophthalmol Vis Sci. 2026;67:10.
PubMed Abstract available

KRISHNA K, Chou B, Gonzalez L, Durkee H, et al
Evaluating Photochemical Interactions Between Rose Bengal Photodynamic Antimicrobial Therapy and Topical Antifungals in Fungal Keratitis Isolates.
Invest Ophthalmol Vis Sci. 2026;67:11.
PubMed Abstract available

SZANTO D, Erekat A, Woods B, Wang JK, et al
Multimodal Deep Learning Differentiates Papilledema and Non-Arteritic Anterior Ischemic Optic Neuropathy From Healthy Eyes.
Invest Ophthalmol Vis Sci. 2026;67:12.
PubMed Abstract available

XIONG J, Lu H, Zhou N, Wu Y, et al
Possible Extension of Inner Scleral Fibers Into the Peripapillary Sclera Detected by Polarization-Sensitive OCT.
Invest Ophthalmol Vis Sci. 2026;67:13.
PubMed Abstract available

ZHU L, Rodrigues-Braz D, Gelize E, Crepin M, et al
A Novel Rat Model for Human Meibomian Gland Dysfunction and Ocular Rosacea.
Invest Ophthalmol Vis Sci. 2026;67:14.
PubMed Abstract available

VEERNALA I, Cuamatzi-Castelan AS, Rajesh A, Gong J, et al
Levodopa Suppresses Choroidal Neovascularization Through a Tyrosinase-Dependent Dual Mechanism.
Invest Ophthalmol Vis Sci. 2026;67:8.
PubMed Abstract available

GUO Y, Luo S, Li W, Wang X, et al
Ferroptosis in Meibomian Gland Progenitor Cells Contributes to Pathogenesis of Meibomian Gland Dysfunction.
Invest Ophthalmol Vis Sci. 2026;67:9.
PubMed Abstract available

BABA S, Meguro A, Kanemaki N, Maeda A, et al
Genetic Link Across Species: SIX6, a Major Human Glaucoma Gene, Confers Susceptibility to Glaucoma in Shiba-Inu Dogs.
Invest Ophthalmol Vis Sci. 2026;67:5.
PubMed Abstract available

QU J, Yang L, Wang X, Zhao L, et al
Establishment of Mouse Meibomian Gland Organoids for In Vitro Modeling of Meibomian Gland Dysfunction.
Invest Ophthalmol Vis Sci. 2026;67:6.
PubMed Abstract available

OSHIRO A, Imanaga N, Terao N, Yamanari M, et al
Evaluation of Melanin Changes in Acute Vogt-Koyanagi-Harada Disease Using Polarization-Sensitive Optical Coherence Tomography.
Invest Ophthalmol Vis Sci. 2026;67:7.
PubMed Abstract available

ZHANG B, Sun Y, Jiang X, Hu Z, et al
METTL16 Inhibits Lens Epithelial Cells Function in Diabetic Cataract via m6A-Modified DKK1-Mediated Wnt/beta-Catenin Signaling.
Invest Ophthalmol Vis Sci. 2026;67:1.
PubMed Abstract available

SEE A, Rojas-Carabali W, Cifuentes-Gonzalez C, Arora A, et al
Are the SUN Criteria Sufficient for Tubercular Uveitis? Findings From a Multinational Registry Study.
Invest Ophthalmol Vis Sci. 2026;67:2.
PubMed Abstract available

YASUDA H, Nakamura S, Shirakawa A, Kuse Y, et al
Inhibition of Pathological Mitochondrial Fission in Retinal Pigment Epithelium Mitigates Choroidal Neovascularization.
Invest Ophthalmol Vis Sci. 2026;67:4.
PubMed Abstract available

LIU S, Li S, Wang Y, Sun W, et al
Genetic Landscape and Clinical Characterization of FRMD7-Related Infantile Nystagmus Based on Large In-House Datasets and Literature Review.
Invest Ophthalmol Vis Sci. 2026;67:30.
PubMed Abstract available

ZHOU T, Sun J, Shi W, Zhou Y, et al
Integrated Transcriptomics and Experimental Validation Reveal That Ellagic Acid Alleviates Fuchs Endothelial Corneal Dystrophy via PLAU/NF-kappaB Signaling.
Invest Ophthalmol Vis Sci. 2026;67:31.
PubMed Abstract available

MANOHARAN MK, Ostrin LA
Interaction Between Near Work and Narrowband Light on Choroidal Thickness.
Invest Ophthalmol Vis Sci. 2026;67:27.
PubMed Abstract available

WU YH, Yu D, Goldstein J, Kwon M, et al
Screening Questions to Identify Low Vision and Acuity-Defined Legal Blindness.
Invest Ophthalmol Vis Sci. 2026;67:28.
PubMed Abstract available

SHIMIZU S, Nemoto H, Ohata S, Aihara M, et al
Effects of Micropulse Laser Trabeculoplasty on Intraocular Pressure and Aqueous Humor Outflow in Pigmented Rabbits.
Invest Ophthalmol Vis Sci. 2026;67:29.
PubMed Abstract available

AKEPOGU J, Shikha D, Kumar BK, Senthil S, et al
Characterization of the Functional Transient Receptor Potential Vanilloid Channels 1 to 4 in Human Corneal Endothelial Cells.
Invest Ophthalmol Vis Sci. 2026;67:20.
PubMed Abstract available

KUMAR S, Sohnen P, Kaur S, Vohra M, et al
Apicobasal Polarity Protein PARD3 Plays an Essential Role in Human Corneal Epithelial Cells.
Invest Ophthalmol Vis Sci. 2026;67:3.
PubMed Abstract available

SHENG W, Wang Q, Huang Y, Gu J, et al
Retinal Amyloid Clearance Enhanced by 40-Hz Light Flicker via MHC-II+ Microglia Regulation in Mice.
Invest Ophthalmol Vis Sci. 2026;67:32.
PubMed Abstract available

LOELIGER J, Gelfman S, Stahl EA, Moscati A, et al
The Impact of ERAP1 and ERAP2 Haplotype Combinations on Susceptibility and Severity of Birdshot Chorioretinitis.
Invest Ophthalmol Vis Sci. 2026;67:51.
PubMed Abstract available

ZHAO X, Duan H, Dou S, Li X, et al
Early Transcriptomic and Pathologic Changes of Col8a2 Mutant Fuchs Endothelial Corneal Dystrophy.
Invest Ophthalmol Vis Sci. 2026;67:53.
PubMed Abstract available

WAN Y, Liu X, Yan X, Wu S, et al
AAV-DJ-Mediated MYOC Silencing as a Gene Therapy Approach for Myocilin-Associated Glaucoma.
Invest Ophthalmol Vis Sci. 2026;67:48.
PubMed Abstract available

ADANI E, Villa Vasquez SS, Lovino M, Bighinati A, et al
Modulation of Aerobic Glycolysis Genes During the Progression of Retinitis Pigmentosa.
Invest Ophthalmol Vis Sci. 2026;67:49.
PubMed Abstract available

ZHANG M, Bai X, Li X, Liu M, et al
Engineered CGRP Eye Drops Restore Tear Secretion via TRPM8-SSN Circuitry in a Postrefractive Surgery Mouse Model.
Invest Ophthalmol Vis Sci. 2026;67:45.
PubMed Abstract available

ZHOU X, Li Z, Zhang X, Xu J, et al
Digoxin Attenuates Ocular Hypertension and Protects Trabecular Meshwork Cells via Ferroptosis Inhibition.
Invest Ophthalmol Vis Sci. 2026;67:46.
PubMed Abstract available

LV K, Peng J, Wang H, Li Y, et al
Olink Proteomic Profiling of Vitreous Humor and Plasma From Proliferative Diabetic Retinopathy Patients Identifies a Novel Inflammatory Molecular Endotype.
Invest Ophthalmol Vis Sci. 2026;67:47.
PubMed Abstract available

JO HC, Pijewska EA, Meleppat RK, Jonnal RS, et al
Combined Mouse Retinal Optoretinography/Electroretinography System to Study Light-Evoked Responses in Animal Models of Retinal Degeneration.
Invest Ophthalmol Vis Sci. 2026;67:39.
PubMed Abstract available

HAMA Y, Muraoka Y, Kogo T, Nishigori N, et al
Cellular-Scale Photoreceptor Remodeling After Macular Hole Surgery Examined by Adaptive Optics Optical Coherence Tomography.
Invest Ophthalmol Vis Sci. 2026;67:40.
PubMed Abstract available

CHO SD, Lee EJ, Kim TW
Microvascular Dropout Within the Lamina Cribrosa in Myopic Eyes With a Parapapillary gamma-Zone and Primary Open-Angle Glaucoma.
Invest Ophthalmol Vis Sci. 2026;67:41.
PubMed Abstract available

SCHWEBLER J, Verma-Fuehring R, Kalantari N, Berger C, et al
Effects of a Novel Dexamethasone Hydrogel Drug Delivery System on Cytokine and Mucin Expression in a Three-Dimensional In Vitro Conjunctival Inflammation Model.
Invest Ophthalmol Vis Sci. 2026;67:42.
PubMed Abstract available

QUARTA A, Feo A, Romano F, Borrelli E, et al
Localized Choriocapillaris Flow Deficits at Perforating Vessel Sites in Myopic Eyes.
Invest Ophthalmol Vis Sci. 2026;67:43.
PubMed Abstract available

SONG QQ, Xu W, Li SM, Wang N, et al
Effect of Repeated Medium-Dose Red Laser Irradiation on Ocular Tissues in Guinea Pigs.
Invest Ophthalmol Vis Sci. 2026;67:52.
PubMed Abstract available

BUSIN M, Yu AC, Scorcia V, Ruzza A, et al
Longitudinal In Vitro Assessment of the Optical Transparency of Preserved Pre-Descemet Layer in the Absence of Corneal Endothelium.
Invest Ophthalmol Vis Sci. 2026;67:54.
PubMed Abstract available

SCHADWINKEL HM, Nissen P, Moritz M, Linke SJ, et al
Layer-Specific Proteomic Profiling of the Human Cornea Reveals Insights Into Structure and Biological Function.
Invest Ophthalmol Vis Sci. 2026;67:44.
PubMed Abstract available

SARRASIN E, Lalys E, Nardou K, Celik E, et al
Downregulation of Cyclin Kinase Inhibitors p16INK4a and p27 in Conjunctival Melanomas.
Invest Ophthalmol Vis Sci. 2026;67:59.
PubMed Abstract available

OWSLEY C, Gao L, Gooden L, Thomas TN, et al
Preserved Contrast Sensitivity in Early and Intermediate Age-Related Macular Degeneration and Marked Loss in Late Stage: ALSTAR2.
Invest Ophthalmol Vis Sci. 2026;67:58.
PubMed Abstract available

DE BRUYN DP, Bassil FL, Wu M, Beasley AB, et al
Circulating Tumor Cells in Uveal Melanoma: Multi-Marker Detection and Association With Disease State.
Invest Ophthalmol Vis Sci. 2026;67:55.
PubMed Abstract available

FOROOZANDEH P, Kaplan N, Qi X, Yang W, et al
PAX6 Deficiency Compromises the Ability of Limbal Epithelial Stem Cells to Properly Differentiate Into Mature Corneal Epithelial Cells.
Invest Ophthalmol Vis Sci. 2026;67:56.
PubMed Abstract available

ZHOU L, Cao Y, Ibukun FA, Yi W, et al
Retinal and Choriocapillaris Thickness and Age in Macaques in Development and Aging.
Invest Ophthalmol Vis Sci. 2026;67:60.
PubMed Abstract available

STAVROPOULOS D, Liu CC, Chen CY, Mirzaliyeva L, et al
Enzymatic Disruption of the Internal Limiting Membrane Enhances Transplanted Retinal Ganglion Cell Survival.
Invest Ophthalmol Vis Sci. 2026;67:57.
PubMed Abstract available

MARTINS PM, Figueiredo I, Cruz N, Gaspar BR, et al
Enhancing Molecular Diagnostic Accuracy in Genetic Eye Disorders Through a Personalized Re-Evaluation Strategy.
Invest Ophthalmol Vis Sci. 2026;67:62.
PubMed Abstract available

SOUNDARARAJAN A, Jayasankar K, Doud EH, Pasteurin RP, et al
Loss of Cathepsin K Impairs Collagen Biogenesis and Enhances Actin Polymerization in Trabecular Meshwork.
Invest Ophthalmol Vis Sci. 2026;67:63.
PubMed Abstract available

BUSZA AM, Kakihara S, Zhuang K, Yamaguchi TC, et al
Baseline Nonperfusion and Deep Capillary Plexus Ischemia Predict Two-Year Retinal Nonperfusion Progression in Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2026;67:64.
PubMed Abstract available

YU JN, Wang SM, Liu JR, Xue F, et al
Crocin Protects Against Retinal Ischemia-Reperfusion Injury via Regulating Sirt6-Mediated Nrf2/HO-1 Pathway in Rats.
Invest Ophthalmol Vis Sci. 2026;67:23.
PubMed Abstract available

WANG E, Feng B, Chen S, Wang H, et al
Silencing of lncRNA HOTAIR Using Eyedrops as a Potential Treatment for Diabetes-Associated Retinal Dysregulation and Dysfunction.
Invest Ophthalmol Vis Sci. 2026;67:24.
PubMed Abstract available

ZOU R, Cai J, Fan L, Liu L, et al
Rod-Cone Dystrophy Related WDR34 Is Essential for Ciliary Integrity and Survival of Mammalian Photoreceptor Cells.
Invest Ophthalmol Vis Sci. 2026;67:26.
PubMed Abstract available

BLACKBURN BJ, Hammoud B, Asroui L, Tarib I, et al
In Vivo Biomechanical Characteristics of Human Corneas With Phase-Decorrelation OCT.
Invest Ophthalmol Vis Sci. 2026;67:25.
PubMed Abstract available

December 2025

JOHNSON M, Overby DR, Stamer WD, Ethier CR, et al
Scientific Concerns About Recent Fluid-Structure Interaction Models of the Aqueous Humor Outflow Pathway.
Invest Ophthalmol Vis Sci. 2025;66:18.
PubMed Abstract available

ZASLAVSKY K, Tumber A, Millar E, Boginskaia O, et al
Genetic Spectrum of Negative Electroretinograms in a Predominantly Pediatric Cohort of 177 Patients.
Invest Ophthalmol Vis Sci. 2025;66:19.
PubMed Abstract available

WANG M, Tang J, Li J, Lv J, et al
Targeting MCM6 Enhances Melphalan Chemosensitivity in Retinoblastoma by Modulating DNA Damage Response.
Invest Ophthalmol Vis Sci. 2025;66:14.
PubMed Abstract available

LAI CC, Wu CJ, Tseng SH, Hsu SM, et al
U1 RNA Detected by Toll-Like Receptor 3 Plays a Role in the Pathogenesis of Pterygium.
Invest Ophthalmol Vis Sci. 2025;66:15.
PubMed Abstract available

CHEN B, Huang Z, Chen J, Wu Y, et al
Effect of Dipyridamole on Experimental Autoimmune Uveitis: Reprogrammed Immune Cell Landscape and Reduced Th17 Pathogenicity.
Invest Ophthalmol Vis Sci. 2025;66:16.
PubMed Abstract available

LIU W, Guo R, Wang S, Chen Z, et al
Association Between Chronic Kidney Disease and Glaucoma: Results From the Lifelines Cohort Study and UK Biobank.
Invest Ophthalmol Vis Sci. 2025;66:17.
PubMed Abstract available

TURA A, Sonntag SR, von Bubnoff NCC, Spielmann M, et al
Missegregation of Chromosome 3 and Generation of Monosomy 3 in the Proliferating Uveal Melanoma Cells Under Hyperglycemia.
Invest Ophthalmol Vis Sci. 2025;66:10.
PubMed Abstract available

AMAN AM, MacGregor S, Diaz-Torres S, Gharahkhani P, et al
Exploring the Shared Genetic Architectures Between Primary Open-Angle Glaucoma and Visual Pathway Regions in the Brain.
Invest Ophthalmol Vis Sci. 2025;66:11.
PubMed Abstract available

GULATI K, Saxena H, Manukonda R, Malpotra S, et al
Metabolic Reprogramming in Retinoblastoma Patients: Treatment Naive Active Retinoblastoma Versus Regressed Tumors Post-Treatment.
Invest Ophthalmol Vis Sci. 2025;66:12.
PubMed Abstract available

WANG X, Liu T, Tan C, Liu L, et al
Regaining Visual Acuity Does Not Restore Motion Extrapolation Deficits in Amblyopia.
Invest Ophthalmol Vis Sci. 2025;66:13.
PubMed Abstract available

ASHBY R, Harb EN, Ostrin LA, Flitcroft DI, et al
IMI: The Role of Light in Refractive Development and Myopia: Evidence from Animal and Human Studies.
Invest Ophthalmol Vis Sci. 2025;66:5.
PubMed Abstract available

HAN M, Shen T, Chang S, Pan L, et al
Perceptual Learning Based on Adaptive Contrast Detection Training for Intermittent Exotropia: A Pilot Double-Masked Randomized Controlled Study.
Invest Ophthalmol Vis Sci. 2025;66:6.
PubMed Abstract available

PAN SY, Weng CH, Tien PT, Lu YA, et al
Association Between Statin Use and Glaucoma Risk: A Population-Based Study.
Invest Ophthalmol Vis Sci. 2025;66:7.
PubMed Abstract available

JARKUM T, Devi P, Solomon JA, Tyler CW, et al
The Impact of Induced Optical Blur on Monocular and Binocular Depth-Related Visuomotor Task Performance.
Invest Ophthalmol Vis Sci. 2025;66:8.
PubMed Abstract available

LOEWEN AD, Tam BM, Chiu CN, Scharbach RT, et al
A Survey of Opsin Localization, Glycosylation, and Light/Chromophore Influence on Degeneration in 26 Rhodopsin-Associated RP Models.
Invest Ophthalmol Vis Sci. 2025;66:9.
PubMed Abstract available

ZHANG H, Liu ZY, Wu L, Yuan J, et al
Retinal Pigment Epithelium Extracellular Vesicles Induce Microglia Polarization in MERTK-Associated Retinal Degeneration.
Invest Ophthalmol Vis Sci. 2025;66:1.
PubMed Abstract available

KAKIHARA S, Zhuang K, Busza A, Fawzi AA, et al
Macular Microaneurysms Are Associated With Chronic Kidney Disease and Deep Capillary Plexus Ischemia in Referable Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:3.
PubMed Abstract available

ROIHUVUO E, Sturgis L, Montaser AB, Tabaka M, et al
Presynaptic Changes in Mouse Rod Photoreceptors During Early Retinitis Pigmentosa.
Invest Ophthalmol Vis Sci. 2025;66:4.
PubMed Abstract available

WANG S, Esquivel Herrera A, Elbasiony E, Lee S, et al
Corneal Myofibroblasts Suppress T-Cell Immunity in Corneal Transplantation.
Invest Ophthalmol Vis Sci. 2025;66:2.
PubMed Abstract available

JONAS JB, Panda-Jonas S, Xu J, Jonas RA, et al
Changes of the Optic Nerve Head and Macula in High Myopia in a 10-Year Follow-Up: The Beijing Eye Study.
Invest Ophthalmol Vis Sci. 2025;66:39.
PubMed Abstract available

LI Z, Harichane I, Cronin T, Sahel JA, et al
Retinal Impairments in Mice Lacking Both Nxnl1 and Nxnl2 Genes.
Invest Ophthalmol Vis Sci. 2025;66:42.
PubMed Abstract available

KUANG L, Ross AE, Chen L, Kanu LN, et al
Overcoming Antimicrobial Resistance in Bacterial Keratitis With an Antibiotic-Eluting Contact Lens.
Invest Ophthalmol Vis Sci. 2025;66:38.
PubMed Abstract available

WANG Y, Zhang S, Zheng Y, Guo D, et al
Ubap1l Knockout Mice Model Recapitulates Retinal Degeneration Phenotype Observed in Patients and Exhibits Irregular Photoreceptor Morphology.
Invest Ophthalmol Vis Sci. 2025;66:35.
PubMed Abstract available

YEO S, Na Y, Lee Y, Park J, et al
Association of 10-2 Visual Field Cluster Patterns With Visual Acuity in Normal-Tension Glaucoma Patients With Central Visual Field Defects.
Invest Ophthalmol Vis Sci. 2025;66:36.
PubMed Abstract available

PARISI V, Ziccardi L, Dell'Aquila C, Barbano L, et al
Functional Assessment of Inner and Outer Macular Layers in Idiopathic Epiretinal Membrane.
Invest Ophthalmol Vis Sci. 2025;66:29.
PubMed Abstract available

FLITCROFT DI, Lingham G, Ying GS, Cui H, et al
Refractive Error Centile Curves for Asian and Western Children and Adolescents: An Individual Level Meta-Analysis.
Invest Ophthalmol Vis Sci. 2025;66:30.
PubMed Abstract available

ZOU X, Fang S, Liu Y, Li H, et al
Detailed Comparison Between Two Main Phenotypes of CRB1-Related Retinal Dystrophy, Pan-retinopathy and Maculopathy.
Invest Ophthalmol Vis Sci. 2025;66:27.
PubMed Abstract available

HU W, Yang H, Zhu Q, Zheng G, et al
KLF10-IN-1 Attenuates RPE Cell Apoptosis and Experimental Diabetic Retinopathy Via the KLF10/PERK/eIF2alpha/ATF4/CHOP Pathway.
Invest Ophthalmol Vis Sci. 2025;66:25.
PubMed Abstract available

LU Y, Wan X, Ye H, Wu Y, et al
Sphingomyelin Synthase 2 Deletion Mitigates Oxidative Stress-Induced NF-kappaB Activation via Lipid Metabolic Reprogramming in Dry Eye Disease.
Invest Ophthalmol Vis Sci. 2025;66:22.
PubMed Abstract available

ZHU P, Chang H, Yang Q, Chen W, et al
Conformational Dynamics of PKM2 Regulate Hypoxia-Induced Pathological Retinal Angiogenesis.
Invest Ophthalmol Vis Sci. 2025;66:23.
PubMed Abstract available

TRIVIZKI O, Wykoff CC, Smoor MA, Rabinovitch D, et al
Effect of Pegcetacoplan on Aqueous Humor Proteome in Geographic Atrophy: A Prospective Exploration.
Invest Ophthalmol Vis Sci. 2025;66:24.
PubMed Abstract available

LI Y, Tang Y, Fu Y, Cui J, et al
A Signature of Typical MRI Features and Time-Intensity Curve Achieves Accurate Diagnosis of Distensible Orbital Venous Malformation.
Invest Ophthalmol Vis Sci. 2025;66:40.
PubMed Abstract available

Erratum in: Acceleration of Myopic Shifts in Refraction and Axial Elongation Begins in the Premyopia Stage.
Invest Ophthalmol Vis Sci. 2025;66:33.
PubMed

ENZENDORFER ML, Mai J, Riedl S, Bogunovic H, et al
Functional Outcomes Across High-Risk OCT-Based Phenotypes in Intermediate Age-Related Macular Degeneration-PINNACLE Study Report 11.
Invest Ophthalmol Vis Sci. 2025;66:54.
PubMed Abstract available

SUZUKI T, Terao R, Nagahara M, Hayashi K, et al
iPLA2beta Protects Retinal Pigment Epithelium From Ferroptosis in a Sodium Iodate-Induced Model of Dry AMD.
Invest Ophthalmol Vis Sci. 2025;66:55.
PubMed Abstract available

ZUO S, Ho SI, Li L, Tang J, et al
Erianin Abrogates Cancerous Vasculogenic Mimicry Through Targeting m5C Methylase NSUN2 in Uveal Melanoma.
Invest Ophthalmol Vis Sci. 2025;66:47.
PubMed Abstract available

HAN X, Zhang J, Chen C, Zhang S, et al
Cyclosporine A Ameliorates Inflammatory Responses in Dry Eye by Inactivating cGAS-STING Signaling Via the Initiation of Autophagy.
Invest Ophthalmol Vis Sci. 2025;66:48.
PubMed Abstract available

YOKOTA H, Hayashi H, Nakagami H, Kushiyama A, et al
Evidence Supporting Autotaxin as a Potential New Drug Treatment Target in Patients With Advanced Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:49.
PubMed Abstract available

KE S, Liang J, Chu WK, Tong Y, et al
Autophagy-Induced Microglial Death Contributes to Neuroinflammation in Acute Optic Nerve Injury.
Invest Ophthalmol Vis Sci. 2025;66:51.
PubMed Abstract available

DING X, Hu J, Ma Y, Yu Y, et al
Characteristics of Retinal Oxygen Kinetics and Blood Flow in Myopia of Different Degrees.
Invest Ophthalmol Vis Sci. 2025;66:52.
PubMed Abstract available

BA M, Huang D, Yang T, Xuan S, et al
Stress-Induced Disruption of Circadian and Neuroimmune Networks in Lacrimal Glands Drives Dry Eye Pathogenesis.
Invest Ophthalmol Vis Sci. 2025;66:53.
PubMed Abstract available

KARACA I, Wei Y, Nelson R, Sassen SH, et al
Association of Mesopic and Dark-Adapted Retinal Sensitivity With Type 1 Macular Neovascularization in Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2025;66:45.
PubMed Abstract available

XUAN S, Yang T, Ba M, Zhang W, et al
Chronic Restraint Stress Misaligns Corneal Clock via beta-Adrenergic and Glucocorticoid Signaling, Altering Epithelial, Neural, Immune, Metabolic States.
Invest Ophthalmol Vis Sci. 2025;66:50.
PubMed Abstract available

VUKMIROVIC A, Morgan WH, Obreschkow D, Abdul-Rahman A, et al
Evidence for the Existence of Two Opposing Pulse Waves in Retinal Vein Segments Within the Optic Disc.
Invest Ophthalmol Vis Sci. 2025;66:43.
PubMed Abstract available

O'CALLAGHAN J, Hudson N, Hanley N, Reddy A, et al
Automated Assessment of Retinal Vascular Integrity Across Species.
Invest Ophthalmol Vis Sci. 2025;66:46.
PubMed Abstract available

YOSHIDA Y, Fujino Y, Michihata N, Akagi A, et al
Effects of Daily Ambient Temperature on Intraocular Pressure: A Time-Series Analysis Using Generalized Additive and Distributed Lag Nonlinear Models.
Invest Ophthalmol Vis Sci. 2025;66:76.
PubMed Abstract available

KRAMER A, Rinsky B, Elbaz-Hayoun S, Khateb S, et al
Altered High-Density Lipoprotein Expression Pattern in the Aqueous Humor From Eyes With Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2025;66:73.
PubMed Abstract available

WELZEL AM, Brandl C, Herold JM, Stingl JV, et al
The Association of Polygenic Risk Score With Glaucoma and Its Related Traits: Results From Two German Population-Based Studies.
Invest Ophthalmol Vis Sci. 2025;66:70.
PubMed Abstract available

PETRACKOVA A, Schovanek J, Karhanova M, Savara J, et al
Transcriptomic Profiling of Orbital Fat Tissue and Ocular Surface Wash in Active Thyroid Eye Disease Requiring Urgent Orbital Decompression.
Invest Ophthalmol Vis Sci. 2025;66:71.
PubMed Abstract available

LI Y, Feng ZX, Cui Y, Sun J, et al
FGF10/IGSF3 Variants in Bony Congenital Nasolacrimal Duct Obstruction: A Genotype-Phenotype Study of Syndromic Versus Isolated Disease.
Invest Ophthalmol Vis Sci. 2025;66:69.
PubMed Abstract available

MACNEIL MA, Mentor W, Birk A
Mitochondrial-Targeted HDAP2 Preserves Retinal Ganglion Cells and Increases Pressure Tolerance in DBA/2J Mice.
Invest Ophthalmol Vis Sci. 2025;66:66.
PubMed Abstract available

AKOTO T, Hao C, Chen Z, Lu X, et al
Proteomic Analysis Provides Insights Into PPIP5K2 Function and Its Impact on Corneal Energy Metabolism.
Invest Ophthalmol Vis Sci. 2025;66:67.
PubMed Abstract available

XIAO B, Hu L, Zhang X, Liu L, et al
Degradation of Elastic Fiber Triggers Lacrimal Gland Dysfunction in Marfan Syndrome Mice.
Invest Ophthalmol Vis Sci. 2025;66:63.
PubMed Abstract available

OKA I, Fujimoto S, Fukui T, Mayumi K, et al
Protective Effects of Estradiol on Disease Progression in a Murine Model of Fuchs Endothelial Corneal Dystrophy.
Invest Ophthalmol Vis Sci. 2025;66:64.
PubMed Abstract available

MOLAEI H, Abbas Farishta R, Farivar R
Letter Distortion Mapping in Amblyopia: Spatial Patterns, Stability, and Relationship to Visual Acuity.
Invest Ophthalmol Vis Sci. 2025;66:65.
PubMed Abstract available

ZHU Y, Yan W, Bian M, Xia X, et al
HDAC4 Promotes Neuroprotection of Retinal Ganglion Cells After Optic Nerve Injury.
Invest Ophthalmol Vis Sci. 2025;66:60.
PubMed Abstract available

BYRNE K, Hudson N, O'Callaghan J, Nevrov D, et al
Dynamic Inner Blood Retina Barrier Disruption in Retinitis Pigmentosa.
Invest Ophthalmol Vis Sci. 2025;66:61.
PubMed Abstract available

KATO N, Haruta M, Arai R, Nagae A, et al
Association of Molar Dose and Early Retinochoroidal Blood Flow Changes After Intravitreal Anti-Vascular Endothelial Growth Factor Therapy.
Invest Ophthalmol Vis Sci. 2025;66:56.
PubMed Abstract available

ZHANG Y, Cao J, Zhang S, Wang S, et al
Extracellular Matrix Stiffness Regulates Cancer Stemness in Uveal Melanoma via the PIEZO1-DOT1L Axis.
Invest Ophthalmol Vis Sci. 2025;66:57.
PubMed Abstract available

LI X, Guo Z, Li C, Zhang S, et al
Glutaredoxin 2 Protects Lens Epithelial Cells From Ferroptosis by Preventing HNRNPA2B1 S-Glutathionylation in Diabetes-Mediated Cataractogenesis.
Invest Ophthalmol Vis Sci. 2025;66:58.
PubMed Abstract available

LI Q, Liu D, Zhang M
Obstructive Sleep Apnea Accelerates Progression of Intermediate Age-Related Macular Degeneration: A Three-Year Prospective Cohort Study.
Invest Ophthalmol Vis Sci. 2025;66:59.
PubMed Abstract available

Erratum in: SIRT1 Inhibits High Glucose-Induced TXNIP/NLRP3 Inflammasome Activation and Cataract Formation.
Invest Ophthalmol Vis Sci. 2025;66:74.
PubMed

Erratum in: Choroidal Mast Cells and Their Degranulation Are a Pivotal Trigger for Myopia Development.
Invest Ophthalmol Vis Sci. 2025;66:75.
PubMed

KOUNTOURAS J, Zavos C, Polyzos SA, Vardaka E, et al
Potential Influence of Helicobacter Pylori on Glaucoma-Related Alterations of Ocular Surface Microbiota and Dry Eye Disease Pathophysiology.
Invest Ophthalmol Vis Sci. 2025;66:72.
PubMed

GAMEIRO GR, Moarefi M, Nguyen B, Hoover A, et al
Retinal Neurovascular and Mitochondrial Function Signatures in Response to a 24-Week Yoga Intervention in Healthy Adults.
Invest Ophthalmol Vis Sci. 2025;66:62.
PubMed Abstract available

November 2025

ZHU X, Ye H, Lu Y, Zhang Q, et al
Somatostatin Ameliorates Corneal Nerve Abnormalities and Inflammation Through Regulation of Macrophage Activities in Dry Eye Disease.
Invest Ophthalmol Vis Sci. 2025;66:18.
PubMed Abstract available

LI R, Zhang H, Yang L, Pan Y, et al
High-Throughput Tear Proteomics Reveals Multi-Faceted Signatures of Thyroid Eye Disease.
Invest Ophthalmol Vis Sci. 2025;66:11.
PubMed Abstract available

FIDANCI A, Flowers CS, Larson C, Engel SA, et al
The Preferred Retinal Locus for Reading in Central Vision Loss.
Invest Ophthalmol Vis Sci. 2025;66:12.
PubMed Abstract available

CAO Q, Wang J, Xu W, Reinach PS, et al
Targeting miR-184 to Enhance Corneal Epithelial Wound Healing: In Vivo Knockout, Antisense Inhibition, and Exosome-Mediated Delivery.
Invest Ophthalmol Vis Sci. 2025;66:13.
PubMed Abstract available

GAO Y, Wang Y, Zhang Y, Yu J, et al
Accelerated Biological Aging and Genetic Pleiotropy in Age-Related Eye Diseases: A Population-Based Cohort and Integrative Genetic Analysis.
Invest Ophthalmol Vis Sci. 2025;66:14.
PubMed Abstract available

CHEN Y, Chen Y, Hess RF, Zhou J, et al
Dynamic Stereopsis Is Abnormal in Treated Anisometropic Amblyopia.
Invest Ophthalmol Vis Sci. 2025;66:10.
PubMed Abstract available

HAN W, Liu Y, Song P, Gu Y, et al
AQP5 Regulates Corneal Nerve Distribution Through NETRIN-1 and SLIT3.
Invest Ophthalmol Vis Sci. 2025;66:6.
PubMed Abstract available

NAM MH, Nahomi RB, Suk J, Panja S, et al
DJ-1 Protects Human Retinal Endothelial Cells From Diabetes-Related Conditions and Prevents Ischemic Damage in Mouse Retinal Capillaries.
Invest Ophthalmol Vis Sci. 2025;66:8.
PubMed Abstract available

KOO D, Kim M, Yang HS, Kim J, et al
Therapeutic Potential of Graphene Quantum Dots on Pterygium Cells.
Invest Ophthalmol Vis Sci. 2025;66:9.
PubMed Abstract available

PAREKH M, Price MO, Price FW, Jurkunas UV, et al
Permanent Senescence Via p16 Leads to Guttae Formation in an In Vitro Human Corneal Endothelial Cell Model.
Invest Ophthalmol Vis Sci. 2025;66:1.
PubMed Abstract available

ASHWORTH KE, Zhang J, D'Amata C, Heon E, et al
USH2A-Mutated Human Retinal Organoids Model Rod-Cone Dystrophy.
Invest Ophthalmol Vis Sci. 2025;66:2.
PubMed Abstract available

TAN R, Shahidzadeh A, Collazo A, Jiang X, et al
The Association of Retinal Capillary Density and Retinal Thickness in Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:3.
PubMed Abstract available

OMAE T, Ono S, Kamiya T, Otani S, et al
Dipeptidyl Peptidase 4, a Novel Adipokine, Impairs Retinal Microcirculation in Patients With Type 2 Diabetes Mellitus.
Invest Ophthalmol Vis Sci. 2025;66:4.
PubMed Abstract available

Retraction of: Agonism of beta3-Adrenoceptors Inhibits Pathological Retinal Angiogenesis in the Model of Oxygen-Induced Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:16.
PubMed

Retraction of: VEGF as a Survival Factor in Ex Vivo Models of Early Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:17.
PubMed

LIU J, Jing Y, Wu J, Lu D, et al
Hypoxia Alters Corneal Circadian Rhythms and Disrupts Epithelial, Neural, and Immune Balance.
Invest Ophthalmol Vis Sci. 2025;66:5.
PubMed Abstract available

FUKUDA Y, Zhang C, Ksander BR, Jo VY, et al
MYEOV Is a Novel Marker of Differentiated Corneal Epithelium.
Invest Ophthalmol Vis Sci. 2025;66:7.
PubMed Abstract available

MENG Z, Liu D, Hu Y, Shi W, et al
PRRX1 Orchestrates Pericyte-Myofibroblast Transition in Pathological Retinal Fibrosis.
Invest Ophthalmol Vis Sci. 2025;66:24.
PubMed Abstract available

XU J, Gao Y, Wang J, Lyv M, et al
GD2-CAR-Engineered Microglia Exhibit Antitumor Effects in Organoids and Animal Models of Retinoblastoma.
Invest Ophthalmol Vis Sci. 2025;66:26.
PubMed Abstract available

REIS LM, Bellingham J, Motta FL, Jurkute N, et al
Abnormal Splicing in the Final Intron of PRX Results in Dominant Congenital Cataract Without Neurological Phenotype.
Invest Ophthalmol Vis Sci. 2025;66:28.
PubMed Abstract available

ROMANOWSKI EG, Schilling BM, Young EK, Mumper SM, et al
Cefiderocol and Moxifloxacin Have Additive and Synergistic Activity Against Pseudomonas aeruginosa Including an Isolate of the 2023 Keratitis Outbreak.
Invest Ophthalmol Vis Sci. 2025;66:19.
PubMed Abstract available

BEQIRI S, Pan H, Kumar BS, Berni A, et al
Changes in Choriocapillaris Flow Deficits Before and After the Onset of Large Choroidal Hypertransmission Defects in AMD.
Invest Ophthalmol Vis Sci. 2025;66:20.
PubMed Abstract available

SHI J, Ikeda SI, Fukuchi T, Chen J, et al
Choroidal Mast Cells and Their Degranulation Are a Pivotal Trigger for Myopia Development.
Invest Ophthalmol Vis Sci. 2025;66:22.
PubMed Abstract available

CINQUE F, de Breuk A, Mhmud H, De Jong S, et al
Disease Progression in Age-Related Macular Degeneration Patients Carrying Rare Variants in the Complement Factor H or Complement Factor I Genes.
Invest Ophthalmol Vis Sci. 2025;66:23.
PubMed Abstract available

WU Q, Dolui S, Taso M, Jiang H, et al
Associations Between Retinal Microvasculature, Orbital Blood Flow, and Cerebral Blood Flow in Healthy Adults.
Invest Ophthalmol Vis Sci. 2025;66:25.
PubMed Abstract available

SEITZ IP, Nyshchuk R, Ellederova Z, Ardan T, et al
Subretinal Injection Volume Correlates to Persistent Outer Retinal Thinning in the Pig Eye.
Invest Ophthalmol Vis Sci. 2025;66:27.
PubMed Abstract available

DEMER JL, Clark RA
Ocular Translation Due to Gravitational Acceleration.
Invest Ophthalmol Vis Sci. 2025;66:21.
PubMed Abstract available

CHEN KY, Chan HC, Chan CM
Can Immune Checkpoint Modulation Redefine Ocular Immunotherapy? Emerging Mechanisms, Challenges, and Translational Opportunities-A Comprehensive Review.
Invest Ophthalmol Vis Sci. 2025;66:53.
PubMed Abstract available

SCHUMAN DM, Suarez MF, Grimsrud AO, Kuhn M, et al
Intracameral Puncture Lowers Intraocular Pressure and Triggers an Immune Response in the Conventional Outflow Tract.
Invest Ophthalmol Vis Sci. 2025;66:54.
PubMed Abstract available

COPPE AM, Iarossi G, Cappelli A, Placidi G, et al
Inner Retina Changes in ABCA4-Related Retinopathy: Structure-Function Relationship.
Invest Ophthalmol Vis Sci. 2025;66:55.
PubMed Abstract available

THOMAS N, Acton JH, Erichsen JT, Fergusson J, et al
The Human Fovea Is Relatively Horizontally Elongated in Infantile Nystagmus.
Invest Ophthalmol Vis Sci. 2025;66:56.
PubMed Abstract available

REDMON SN, Yarishkin O, Rudzitis CN, Lakk M, et al
Mechano- and Glucocorticoid-Sensitive TREK-1 Channels Regulate Conventional Outflow and Intraocular Pressure.
Invest Ophthalmol Vis Sci. 2025;66:57.
PubMed Abstract available

CHEN Z, Tang Y, Jiang J, Zhang D, et al
Inhibition of Histone Methyltransferase G9a Activates Autophagy and Provides Protection in Dry Eye Disease.
Invest Ophthalmol Vis Sci. 2025;66:52.
PubMed Abstract available

KERBER KL, Dhungel D, Flores K, Beri S, et al
Longitudinal Evaluation of Static and Dynamic Accommodation in Young Children.
Invest Ophthalmol Vis Sci. 2025;66:47.
PubMed Abstract available

RAKSHIT A, Schmid KL, Majhi D, Webber AL, et al
Visuo-Cognitive Executive Functions in Amblyopia and Strabismus: Associations With Function and Quality of Life.
Invest Ophthalmol Vis Sci. 2025;66:48.
PubMed Abstract available

JURKOVICOVA L, Palenik J, Ruzickova A, Roman R, et al
The Pattern Glare Test: Further Exploration of Methodological and Demographic Factors.
Invest Ophthalmol Vis Sci. 2025;66:49.
PubMed Abstract available

WIN KY, Ng YBZ, Hu Q, Mohammad Naim SRB, et al
Three-Dimensional Morphometric Analysis of Exfoliative Material Using Ultrahigh-Resolution OCT in Exfoliation Syndrome.
Invest Ophthalmol Vis Sci. 2025;66:50.
PubMed Abstract available

SU JZ, Wang J, Gao ZL, Ding L, et al
Scutellarin Protects Retinal Ganglion Cells in Glaucoma by Targeting the Hsp90aa1-MAPK Pathway to Inhibit Apoptosis.
Invest Ophthalmol Vis Sci. 2025;66:44.
PubMed Abstract available

KAKIHARA S, Zhuang K, Fawzi AA
Macular Deep Capillary Plexus Ischemia as a Biomarker for Identifying Referable Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:45.
PubMed Abstract available

FLEURIET J, Belloir T, Walton MMG
Saccade-Related Activity in Superior Colliculus Predicts Eye Choice for Goal-Directed Saccades in Monkeys With Strabismus.
Invest Ophthalmol Vis Sci. 2025;66:46.
PubMed Abstract available

LUO J, Zeng J, Wang H, Qian Q, et al
Characterization of Early Metastatic Subpopulations in Uveal Melanoma: Single-Cell Insights Into SPP1+ Cells and Their Interactions With Macrophages.
Invest Ophthalmol Vis Sci. 2025;66:37.
PubMed Abstract available

LI Z, Zhao Z, Zhang K, Jiang F, et al
Predictive Utility of Genetic Risk for Myopic Maculopathy Presence and Progression in a Chinese High Myopia Cohort.
Invest Ophthalmol Vis Sci. 2025;66:38.
PubMed Abstract available

STERK M, Thaler E, Fajmut A, Hawlina M, et al
Gap Junctional Versus Paracrine Signaling in the Human Lens Epithelium: Analysis Based on Multicellular Ca(2)(+) Imaging and Computational Modeling.
Invest Ophthalmol Vis Sci. 2025;66:39.
PubMed Abstract available

WANG Y, Liu S, Huang Q, Cheng Y, et al
Mfn2 Regulates Scleral Remodeling in Myopia by Maintaining Endoplasmic Reticulum Homeostasis in Scleral Fibroblasts.
Invest Ophthalmol Vis Sci. 2025;66:40.
PubMed Abstract available

MAO Z, Yang W, Chao Y, Chen Z, et al
Palmitic Acid Induces Ferroptosis in Retinal Microvascular Endothelial Cells by Palmitoylation of Keap1 to Affect Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:41.
PubMed Abstract available

XIA F, Shi S, Palacios E, Ju WK, et al
CXCR3 Deficiency Alleviates Retinal Ganglion Cell Loss by Regulating Neuron-Astrocyte Communication in a Mouse Model of Glaucoma.
Invest Ophthalmol Vis Sci. 2025;66:42.
PubMed Abstract available

YAN X, Huang Y, Yang S, Chen G, et al
Optimization and Application of Seahorse Glycolytic Stress Test in Mouse Corneal Tissues: Revealing Metabolic Profiles in Injury Models.
Invest Ophthalmol Vis Sci. 2025;66:43.
PubMed Abstract available

JONAS JB, Bikbov MM, Kazakbaeva GM, Wang YX, et al
Glaucomatous, Glaucoma-Like, and Non-Glaucomatous Optic Neuropathy in High Myopia: The Two-Continent Study.
Invest Ophthalmol Vis Sci. 2025;66:30.
PubMed Abstract available

NGUYEN J, Verma S, Vuong VT, Queener H, et al
Engineered Tandem Thymosin Peptide Promotes Corneal Wound Healing.
Invest Ophthalmol Vis Sci. 2025;66:31.
PubMed Abstract available

HOTTE GJ, Kolijn PM, de Bie M, Swagemakers SMA, et al
Serum Biomarkers Linked to Disease Activity, Severity, and Methylprednisolone Response in Graves' Orbitopathy: A Proteomic Study.
Invest Ophthalmol Vis Sci. 2025;66:32.
PubMed Abstract available

RAUTAVAARA Y, Sefawi I, Vattulainen M, Moustardas P, et al
Central Corneal Epithelial Wounding Accelerates Aniridia-Associated Keratopathy in PAX6-Deficient Mice.
Invest Ophthalmol Vis Sci. 2025;66:33.
PubMed Abstract available

ZOBOR D, Knezy K, Besztercei B, Szigeti A, et al
Applicability of Electroretinography Measurements in Congenital PAX6-Related Aniridia.
Invest Ophthalmol Vis Sci. 2025;66:36.
PubMed Abstract available

LADURNER G, Harper DJ, May L, Worm S, et al
Comparative Investigation of the Retinal Phenotype of Three Mouse Models of Alzheimer's Disease With Optical Coherence Tomography.
Invest Ophthalmol Vis Sci. 2025;66:35.
PubMed Abstract available

BIKBOV MM, Kazakbaeva GM, Panda-Jonas S, Iakupova EM, et al
Retinal Nerve Fiber Layer Thickness in Children: The Ural Children Eye Study.
Invest Ophthalmol Vis Sci. 2025;66:34.
PubMed Abstract available

QUARTA A, Corradetti G, Romano F, Trinco A, et al
Distinct Profiles of Choriocapillaris Involvement in Extensive Macular Atrophy With Pseudodrusen-Like Appearance and Geographic Atrophy.
Invest Ophthalmol Vis Sci. 2025;66:64.
PubMed Abstract available

REN M, Chen X, Gao P, Huang Y, et al
RPGRORF15 Mutations Disrupt Lysosomal Lipid Metabolism in Retinal Pigment Epithelium Cells and Cause Retinitis Pigmentosa.
Invest Ophthalmol Vis Sci. 2025;66:61.
PubMed Abstract available

DONG Y, Hao Z, Liu Y, Chang A, et al
Preclinical Assessment of Mitochondrial-Targeted ND4 Gene Therapy for Leber Hereditary Optic Neuropathy.
Invest Ophthalmol Vis Sci. 2025;66:58.
PubMed Abstract available

SOOD S, Sinha NR, Tiwari A, Ruterschmidt E, et al
Epigenetic Reprogramming Via Sodium Butyrate Induces Corneal Myofibroblast Dedifferentiation In Vitro and Inhibits Fibrosis In Vivo.
Invest Ophthalmol Vis Sci. 2025;66:59.
PubMed Abstract available

ZHENG X, Zhao F, Chen H, Lin H, et al
A Novel Rabbit Model of Angle-Closure Glaucoma Via Ciliary Block and Elevated Trans-Lens Pressure Difference.
Invest Ophthalmol Vis Sci. 2025;66:60.
PubMed Abstract available

October 2025

WANG YA, Alur RP, Kalaskar V, George A, et al
Transgene-Induced Chromosomal Rearrangement With Aberrant Human Vascular Endothelial Growth Factor at the Optic Fissure Leads to Uveal Coloboma in Mice.
Invest Ophthalmol Vis Sci. 2025;66:7.
PubMed Abstract available

WANG N, Yao F, Xu W, Feng T, et al
The Transcription Factor Islet-1 Regulates Diabetes-Induced Inner Blood-Retinal Barrier Disruption.
Invest Ophthalmol Vis Sci. 2025;66:8.
PubMed Abstract available

CHEN R, Zhao Z, Yusufu M, Shang X, et al
Choroidal Vascular Fingerprints From Indocyanine Green Angiography Unveil Chorioretinal Disease State.
Invest Ophthalmol Vis Sci. 2025;66:3.
PubMed Abstract available

GEORGE A, Pfister T, DeYoung C, Sharma R, et al
TYROSINASE-Deficient Human Retinal Pigment Epithelium Exhibits Melanosome Maturation Defects.
Invest Ophthalmol Vis Sci. 2025;66:4.
PubMed Abstract available

RUZAFA N, Pereiro X, Prieto-Lopez L, Urcola A, et al
Characterization of the Most Resistant and Vulnerable Retinal Ganglion Cell Subtypes in a Chronic Model of Glaucoma in Rat.
Invest Ophthalmol Vis Sci. 2025;66:5.
PubMed Abstract available

VOOGELAAR M, Tedja MS, Guggenheim JA, Saw SM, et al
IMI-Myopia Genetics Report.
Invest Ophthalmol Vis Sci. 2025;66:22.
PubMed Abstract available

CHOU HD, Eleuteri A, Kalirai H, Hussain RN, et al
Monosomy 3 Prediction by Clinical Features and BAP1 Staining and Its Value When Integrated in Liverpool Uveal Melanoma Prognosticator Online (LUMPO3).
Invest Ophthalmol Vis Sci. 2025;66:17.
PubMed Abstract available

WANG X, Liu T, Tan C, Song Y, et al
Integration of Visual Motion Signals in Reduced Visual Conditions.
Invest Ophthalmol Vis Sci. 2025;66:18.
PubMed Abstract available

XIE R, Mao T, Su N, Yuan S, et al
Mapping Macrophage Diversity in Coats' Disease: A Lipid-Associated Subset in the Pathogenesis of Exudative Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:19.
PubMed Abstract available

FIESS A, Gissler S, Grabitz S, Mildenberger E, et al
Optic Disc Characteristics in Children Born Preterm With and Without ROP: Results From the Gutenberg Prematurity Eye Study Young (GPESY).
Invest Ophthalmol Vis Sci. 2025;66:21.
PubMed Abstract available

HUANG YS, Lu WT, Chiu IH, Chien PM, et al
Hidden Splicing Variants in Inherited Retinal Degeneration: Discovery and Functional Insight.
Invest Ophthalmol Vis Sci. 2025;66:12.
PubMed Abstract available

KOLLER AF, Kasmann-Kellner B, Benseler F, Tschernig T, et al
Alterations of Photoreceptor Synaptic Ribbons in the Retina of a Human Patient With Oculocutaneous Albinism Type 1 (OCA1).
Invest Ophthalmol Vis Sci. 2025;66:14.
PubMed Abstract available

SHIMOKAWA S, Fukushima M, Shimokawa S, Hisai T, et al
Preclinical Evaluation of Pitavastatin Nanoparticles for Preserving Cone Photoreceptors in Mouse Models of RP.
Invest Ophthalmol Vis Sci. 2025;66:15.
PubMed Abstract available

MOLBECH CR, Boegh MM, Nielsen MK, Subhi Y, et al
Impaired Vagal Tone Function-Based Regulation of Systemic Inflammation in Patients With Neovascular Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2025;66:16.
PubMed Abstract available

AZIZZADEH PORMEHR L, Manian KV, Cho HE, Redmond TM, et al
Higher Throughput Assays for Understanding the Pathogenicity of Variants of Unknown Significance in the RPE65 Gene.
Invest Ophthalmol Vis Sci. 2025;66:10.
PubMed Abstract available

Erratum in: IMI-Nonpathological Human Ocular Tissue Changes With Axial Myopia.
Invest Ophthalmol Vis Sci. 2025;66:13.
PubMed

ZHAO H, Li X, Zhang X, Zhou Q, et al
Comparative Transcriptomic Profiling of Corneal Compartments Using Single-Cell and Single-Nucleus Sequencing.
Invest Ophthalmol Vis Sci. 2025;66:11.
PubMed Abstract available

YU C, Rupasinghe N, Robman L, Hodgson LAB, et al
Development and Validation of Polygenic Scores for Retinal Vessel Calibers.
Invest Ophthalmol Vis Sci. 2025;66:9.
PubMed Abstract available

WU M, He HL, Wang C, Wang B, et al
Maresin 1 Ameliorates Blue Light Overexposure-Induced Meibomian Gland Dysfunction via Inhibition of NLRP3/Caspase-1/GSDMD-Mediated Pyroptosis.
Invest Ophthalmol Vis Sci. 2025;66:29.
PubMed Abstract available

DAI J, Wang X, Han Y, Xue C, et al
High Myopia-Induced Optic Nerve Head Deformation and Glaucoma Progression: A Three-Year Follow-Up Study.
Invest Ophthalmol Vis Sci. 2025;66:30.
PubMed Abstract available

WU V, Roman AJ, Galsterer EL, Ansari G, et al
Measuring Rod- and Cone-Photoreceptor-Specific Vision in Inherited Retinal Diseases Using a Commercial Perimeter.
Invest Ophthalmol Vis Sci. 2025;66:31.
PubMed Abstract available

SHA X, Yu G, Wu C, Teng X, et al
Fusarium solani Activates PANoptosis and Modulates Immune Response in Fungal Keratitis.
Invest Ophthalmol Vis Sci. 2025;66:27.
PubMed Abstract available

NAIR AP, Tejwani S, Dinakaran S, Shetty N, et al
Elevated Neurodegeneration Markers in the Aqueous Humor of Primary Open Angle and Normal Tension Glaucoma Patients Correlate With Disease Severity.
Invest Ophthalmol Vis Sci. 2025;66:24.
PubMed Abstract available

MONTOYA SA, Hillstrom AJ, Allison KD, Mulder CB, et al
Visual Snow Is Susceptible to the Motion Aftereffect.
Invest Ophthalmol Vis Sci. 2025;66:23.
PubMed Abstract available

Erratum in: MicroRNA-124 Dysregulation Is Associated With Retinal Inflammation and Photoreceptor Death in the Degenerating Retina.
Invest Ophthalmol Vis Sci. 2025;66:28.
PubMed

DEGUCHI H, Tanioka H, Koga Y, Yamashita T, et al
The Role of ARL13B in Mitochondrial Homeostasis in Cultured Human Corneal Endothelial Cells.
Invest Ophthalmol Vis Sci. 2025;66:25.
PubMed Abstract available

ZHANG H, Liu K, Sun M, Rong T, et al
Impact of Aging and Light Stimulation Parameters on Retinal Hyperemia Responses in Functional Optical Coherence Tomography Angiography.
Invest Ophthalmol Vis Sci. 2025;66:26.
PubMed Abstract available

LI X, Yuan J, Chen Z, Zhang Y, et al
Development of Two In Vitro ND1-LHON Models for Evaluating Gene Therapy Efficacy.
Invest Ophthalmol Vis Sci. 2025;66:34.
PubMed Abstract available

LIAO N, Jiang H, Qin Y, Wan M, et al
Binocular Contrast Sensitivity Function in Children With Anisometropic Amblyopia.
Invest Ophthalmol Vis Sci. 2025;66:35.
PubMed Abstract available

VUORI N, Antikainen AA, Haukka JK, Harjutsalo V, et al
Exome and Genome Sequencing Reveals Novel Variants for Severe Diabetic Retinopathy in Type 1 Diabetes.
Invest Ophthalmol Vis Sci. 2025;66:36.
PubMed Abstract available

ZHU T, Yang J, Xu M, He M, et al
Spatial Proteomic Analysis Highlights Molecular Reprogramming in Optic Nerve Invasive Retinoblastoma.
Invest Ophthalmol Vis Sci. 2025;66:37.
PubMed Abstract available

ZHANG L, Li H, Duan C, Ju Y, et al
Axial Length Profiles in Inherited Retinal Diseases-A Genotypic and Phenotypic Analysis.
Invest Ophthalmol Vis Sci. 2025;66:32.
PubMed Abstract available

CAI W, Hu Y, Chen X, Morgan IG, et al
Acceleration of Myopic Shifts in Refraction and Axial Elongation Begins in the Premyopia Stage.
Invest Ophthalmol Vis Sci. 2025;66:33.
PubMed Abstract available

HAN L, Mupparapu R, Chrysostomou V, Bell KC, et al
Longitudinal Structural and Microvascular Imaging of Mouse Retina After Optic Nerve Crush Using Temporal Speckle-Averaging Visible Light OCT.
Invest Ophthalmol Vis Sci. 2025;66:56.
PubMed Abstract available

NGUYEN TN, Terry L, Guggenheim JA
Mendelian Randomization Studies of Myopia: Choosing the Right Summary Statistics.
Invest Ophthalmol Vis Sci. 2025;66:57.
PubMed Abstract available

SAH RP, Meyer D, Kollbaum P
Dynamics of Accommodative Behavior Under Prolonged Viewing of Electronic Devices in Young Adults.
Invest Ophthalmol Vis Sci. 2025;66:53.
PubMed Abstract available

FAURITE C, Michaud C, Cousin E, Olivier P, et al
Neurobehavioral Changes in Macular Degeneration: Spatial Frequency Use in Scene Recognition.
Invest Ophthalmol Vis Sci. 2025;66:54.
PubMed Abstract available

KOSOVICHEVA A, Ahmed Z, Chaudhry N, Lim B, et al
Intact Perceptual Interactions of Interocular Temporal Phase and Contrast Disparities in Amblyopia.
Invest Ophthalmol Vis Sci. 2025;66:55.
PubMed Abstract available

GORSKI M, Grunin M, Herold JM, Frohlich B, et al
Diverse-Ancestry GWAS of Age-Related Macular Degeneration on 16,108 Examined Cases and 18,038 Controls.
Invest Ophthalmol Vis Sci. 2025;66:51.
PubMed Abstract available

JASKIEWICZ-RAJEWICZ K, Wysocka A, Maleszka-Kurpiel M, Matuszewska-Mach E, et al
Inter-Eye Molecular Discrepancies in the Corneal Epithelium Point to TFRC in the Keratoconus Severity Signature and Mechanism of Cone Formation.
Invest Ophthalmol Vis Sci. 2025;66:52.
PubMed Abstract available

PILCH J, Krzyzinski M, Markiewicz A, Biecek P, et al
Dualistic Role of MITF in Uveal Melanoma: Defining Two Distinct Cellular Subpopulations With Prognostic and Therapeutic Implications.
Invest Ophthalmol Vis Sci. 2025;66:45.
PubMed Abstract available

CIDECIYAN AV, Neuhauser H, Roman AJ, Aleman TS, et al
Location and Identity of Photoreceptors Contributing to the Full-Field Stimulus Test (FST).
Invest Ophthalmol Vis Sci. 2025;66:46.
PubMed Abstract available

PRASAD D, Siddiqui MG, Dar MAA, Sonar R, et al
Assessing the Independent and Combined Effects of Hyperosmolarity and Inflammatory Stress on Human Corneal Epithelial Cells.
Invest Ophthalmol Vis Sci. 2025;66:47.
PubMed Abstract available

KUMAR R, Sinha NR, Jeffrey MT, Hofmann AC, et al
Single-Cell Transcriptomics Shows Cellular Heterogeneity, Intercellular Communication, and Extracellular Matrix Remodeling in Corneal Fibrosis In Vivo.
Invest Ophthalmol Vis Sci. 2025;66:48.
PubMed Abstract available

AHN SJ, He J, Tai V, Winter KP, et al
Comparison of Retinal and Choroidal OCT Measures and Features at Term Equivalent Age in Preterm and Term Infants.
Invest Ophthalmol Vis Sci. 2025;66:40.
PubMed Abstract available

GUO Y, Lin J, Wu H, Li H, et al
Helicobacter pylori Infection's Dual Impact on the Ocular Surface: Tear Secretion Disruption and Ocular Surface Microbiome Alteration.
Invest Ophthalmol Vis Sci. 2025;66:41.
PubMed Abstract available

HABIBI A, Ashrafkhorasani M, Emamverdi M, Chinasigari PR, et al
Total Retinal Pigment Epithelium Thickness and Reflectivity, in Relation to Histology and Vision, at the Aging-AMD Transition: ALSTAR2 Baseline.
Invest Ophthalmol Vis Sci. 2025;66:42.
PubMed Abstract available

AYERAKWAH PA, Kang BS, Liang Y, Chan HH, et al
Astigmatic Blur in Partial Visual Field Exposure Induces Astigmatism Compensation in Developing Chick Eyes.
Invest Ophthalmol Vis Sci. 2025;66:43.
PubMed Abstract available

JOSHI MR, Subedi A, Basnet GB, Zahidi AAA, et al
Deficits in Motion and Form Perception in Infantile Nystagmus Syndrome.
Invest Ophthalmol Vis Sci. 2025;66:44.
PubMed Abstract available

SHAH J, Zhuang K, Kakihara S, Fawzi AA, et al
Understanding How Low Luminance Visual Deficit Progresses With Advancing Diabetic Macular Ischemia and Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:38.
PubMed Abstract available

TANG J, Feng Z, Jiang N, Zhao G, et al
CD40-CD154 Interactions Induced Progressive Neurodegeneration in Acute Ocular Hypertension Mice.
Invest Ophthalmol Vis Sci. 2025;66:39.
PubMed Abstract available

JAUCH AS, Schwenzer N, von der Emde L, Wall K, et al
Super-Resolution Near-Infrared Autofluorescence Microscopy Depicts Melanin Containing Organelles of the Retinal Pigment Epithelium in Human Donor Eyes.
Invest Ophthalmol Vis Sci. 2025;66:50.
PubMed Abstract available

FERET N, Ter Schiphorst S, Kindermans J, Crowdy H, et al
Temporal Analysis of Tear Fluid Proteome Reveals Critical Corneal Repair Events After Photorefractive Surgery.
Invest Ophthalmol Vis Sci. 2025;66:49.
PubMed Abstract available

September 2025

PATIL CD, Naqvi RA, Borase H, Valverde A, et al
Antagonizing Viral MicroRNAs Reduces Ocular HSV-1 Pathogenesis and Enhances Mucosal Immune Homeostasis.
Invest Ophthalmol Vis Sci. 2025;66:16.
PubMed Abstract available

WANG J, Hormel T, Park DW, Haq S, et al
Quantifying Choriocapillaris Flow Deficits in Diabetic Retinopathy Using Projection-Resolved OCT Angiography.
Invest Ophthalmol Vis Sci. 2025;66:13.
PubMed Abstract available

PARSSINEN O, Franssila ML, Nordhausen K, Mattinen M, et al
The Prevalence of Myopia in Finnish Conscripts Has not Increased in Recent Decades and Is Lower Than in Many East and Southeast Asian Countries.
Invest Ophthalmol Vis Sci. 2025;66:10.
PubMed Abstract available

YANG J, Bernardo-Colon A, Becerra SP
Lack of Pnpla2 Accelerates Progression of AMD-Like Features in Mice.
Invest Ophthalmol Vis Sci. 2025;66:11.
PubMed Abstract available

TESTA F, Karali M, Boccia R, Pisani D, et al
Cystoid Macular Edema in Non-Syndromic Retinitis Pigmentosa: Associations With Causative Genes in a Large Cohort.
Invest Ophthalmol Vis Sci. 2025;66:5.
PubMed Abstract available

DEMER JL, Clark RA
Functional Anatomy of Ocular Counter-Rolling in Superior Oblique Palsy.
Invest Ophthalmol Vis Sci. 2025;66:6.
PubMed Abstract available

YU Y, Zhang Z, Zhai Z, Sun B, et al
A Novel Mouse Model of Granular Corneal Dystrophy Type II Reveals Impaired Autophagy and Recapitulates Human Pathogenesis.
Invest Ophthalmol Vis Sci. 2025;66:7.
PubMed Abstract available

KHADKA NK, Hazen P, Akinola O, Pu X, et al
Lipid and Cholesterol Peroxidation Leads to alpha-Crystallin Membrane Aggregation and Cataract Formation.
Invest Ophthalmol Vis Sci. 2025;66:8.
PubMed Abstract available

PARK M, Choi SW, Jeong DU, Shin HS, et al
Nkx3.2 Inhibits Retinal Degeneration by Modulating Inflammation and Cell Death in RPE.
Invest Ophthalmol Vis Sci. 2025;66:2.
PubMed Abstract available

KAI JY, Dong XX, Li DL, Hu DN, et al
Association of Plasma Omega-3 Fatty Acids With POAG.
Invest Ophthalmol Vis Sci. 2025;66:3.
PubMed Abstract available

BITAN J, Poncet AF, Lecigne C, Devos A, et al
Novel BEST1 Variant Characterization in a Large French Cohort in Light of Updated Bestrophin-1 Structure-Function Correlation.
Invest Ophthalmol Vis Sci. 2025;66:4.
PubMed Abstract available

Erratum in: Isolated Mitochondrial Transplantation as a Novel Treatment for Corneal Chemical Burns.
Invest Ophthalmol Vis Sci. 2025;66:14.
PubMed

Erratum in: Characterization of the Retinal Circulation of the Mouse.
Invest Ophthalmol Vis Sci. 2025;66:15.
PubMed

TAHHAN N, Bullimore MA, He X, Ostrin LA, et al
IMI-2025 Digest.
Invest Ophthalmol Vis Sci. 2025;66:27.
PubMed Abstract available

CHEN C, Xie T, Zhang H, Chang L, et al
Na-Cl Cotransporter (SLC12A3) Inhibition Exacerbates Age-Related Macular Degeneration Via the Nrf2/HO-1 Ferroptosis Pathway.
Invest Ophthalmol Vis Sci. 2025;66:24.
PubMed Abstract available

LIN PH, Kang EY, Makrides N, Lee W, et al
Novel Grm6 Variant in a no b-wave (nob) Mouse Model: Phenotype Characterization and Gene Therapy.
Invest Ophthalmol Vis Sci. 2025;66:20.
PubMed Abstract available

SRENG S, Chung J, Toh A, Zhen YNB, et al
Structure-Function Associations of Choroidal Thickness With Retinal Sensitivity in Myopia.
Invest Ophthalmol Vis Sci. 2025;66:21.
PubMed Abstract available

HUNT C, Yoon HJ, Lirio A, Coley K, et al
Genome-Wide Insights Into the Genes and Pathways Shaping Human Foveal Development: Redefining the Genetic Landscape of Foveal Hypoplasia.
Invest Ophthalmol Vis Sci. 2025;66:22.
PubMed Abstract available

HE Y, Zhou J, Wang J, Huang S, et al
Novel Visceral Obesity Indicators and Associated Metabolic Fingerprint in Incident Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:17.
PubMed Abstract available

OSKAN EE, Agin A, Ozturk M, Onder F, et al
Evaluation of Reflectivities of RPE, ELM, EZ, and Their Relationship With Subretinal Fluid Properties in Central Serous Chorioretinopathy.
Invest Ophthalmol Vis Sci. 2025;66:19.
PubMed Abstract available

LIU F, Li Q, Su J, Fu J, et al
RP1 Dual-AAV Gene Therapy Preserves Retinal Structure and Ameliorates Photoreceptor Degeneration in a Murine Model of Retinitis Pigmentosa.
Invest Ophthalmol Vis Sci. 2025;66:29.
PubMed Abstract available

KARUNARATNE S, Wu M, Yu X, Kent SJ, et al
Altered Corneal T-Cell Motility and Sensory Nerve Features in Older Adults With Human Immunodeficiency Virus Infection.
Invest Ophthalmol Vis Sci. 2025;66:23.
PubMed Abstract available

BAEZ HC, LaPorta JM, Walker AD, Fischer WS, et al
Inner Limiting Membrane Peel Extends In Vivo Calcium Imaging of Retinal Ganglion Cell Activity Beyond the Fovea in Non-Human Primate.
Invest Ophthalmol Vis Sci. 2025;66:25.
PubMed Abstract available

WU W, McRae J, Brown A, Agbaga MP, et al
Tropism and Retinal Transduction Efficiency of Adeno-Associated Virus Serotypes in Mice.
Invest Ophthalmol Vis Sci. 2025;66:18.
PubMed Abstract available

TOLMAN NG, Simon M, Juarez FA, Zhang C, et al
Absence of Glaucoma in Tg-MYOCY437H Mice of Diverse Genetic Backgrounds.
Invest Ophthalmol Vis Sci. 2025;66:40.
PubMed Abstract available

VILLAFUERTE-TRISOLINI C, Le SM, Sin TN, Huynh L, et al
Systemic and Local Lipids in Nonhuman Primates With Drusen and Age-Related Maculopathies.
Invest Ophthalmol Vis Sci. 2025;66:41.
PubMed Abstract available

HE Z, Peng X, Feng Y, Li Z, et al
LINC02099 Promotes Retinal Extracellular Matrix Deposition in Diabetic Mice Via the miRNA-214-3p/CTSS Axis.
Invest Ophthalmol Vis Sci. 2025;66:42.
PubMed Abstract available

HAJ NAJEEB B, Gerendas BS, Sacu S, Leingang O, et al
Reshaping the Burden of nAMD: National, Regional, and Global Prevalence of MNV3 and Its Correlation With Life Expectancy-The RAP Study, Report 7.
Invest Ophthalmol Vis Sci. 2025;66:37.
PubMed Abstract available

ZHAO X, Ren Z, Cao D, Shao Z, et al
Pre-Colonization of Bacillus siamensis on Ocular Surface Mitigates Fusarium keratitis Through Direct Antifungal Activity and Pre-Activation of NF-kappaB Pathway.
Invest Ophthalmol Vis Sci. 2025;66:38.
PubMed Abstract available

BULLIMORE MA, Saunders KJ, Baraas RC, Berntsen DA, et al
IMI-Interventions for Controlling Myopia Onset and Progression 2025.
Invest Ophthalmol Vis Sci. 2025;66:39.
PubMed Abstract available

GARDINER SK, Reynaud J, Cull G, Yang H, et al
Relations Between Pulsatility in the Optic Nerve Head or Peripapillary Retinal Vessels and the Rate of Progression in Glaucoma.
Invest Ophthalmol Vis Sci. 2025;66:34.
PubMed Abstract available

SHEN RY, Zhang Y, Chen LJ, Cheung CY, et al
Ocular and Systemic Risk Factors and Biomarkers for Primary Glaucoma: An Umbrella Review of Systematic Reviews With Meta-Analyses.
Invest Ophthalmol Vis Sci. 2025;66:35.
PubMed Abstract available

LI C, Zhou L, Luo T, Sun H, et al
Integrative Multiomics Identifies CD64(+) Monocytes as Potential Contributors to Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2025;66:32.
PubMed Abstract available

MARGETTS M, Rufus-Toye R, Jiang X, Leo SM, et al
Selective Impairment of Rod-Driven Vision in Vitamin A Deficiency: Insights From Examining the Effect of Desensitizing Backgrounds.
Invest Ophthalmol Vis Sci. 2025;66:30.
PubMed Abstract available

QIU C, Zhang T, Wang Q, Yang K, et al
The Role of Connexin 36 Gap Junctions in Retinal Ganglion Cell Death After Corneal Alkali Burns.
Invest Ophthalmol Vis Sci. 2025;66:43.
PubMed Abstract available

Erratum in: Cellular-Level Visualization of Retinal Pathology in Multiple Sclerosis With Adaptive Optics.
Invest Ophthalmol Vis Sci. 2025;66:36.
PubMed

WANG F, Sun X, Dong Y, Cheng F, et al
Zeb1 Facilitates Nitrogen Mustard-Induced Corneal Epithelial Wound Healing by Maintaining Epithelial Renewability.
Invest Ophthalmol Vis Sci. 2025;66:33.
PubMed Abstract available

ZHANG R, Yu C, Li Y, Dong J, et al
Topical Application of Everolimus Attenuates Lens-Induced Myopia Through mTORC1 Suppression.
Invest Ophthalmol Vis Sci. 2025;66:55.
PubMed Abstract available

GU X, Truong T, Heaster-Ford T, Kim TH, et al
Evaluating the Optic Nerve Crush Model to Understand the Function of Microglia in Glaucoma Neuroprotection.
Invest Ophthalmol Vis Sci. 2025;66:56.
PubMed Abstract available

HUA X, Hormel TT, Wang J, Choi D, et al
Characterizing Long-Chain 3-Hydroxy-Acyl-CoA Dehydrogenase Deficiency (LCHADD) Chorioretinopathy Using OCT and OCTA.
Invest Ophthalmol Vis Sci. 2025;66:57.
PubMed Abstract available

FRIGELLI M, Ariza Gracia MA, Aydemir ME, Torres-Netto EA, et al
Predicting the Effects of Customized Corneal Cross-Linking on Corneal Geometry.
Invest Ophthalmol Vis Sci. 2025;66:51.
PubMed Abstract available

KAROUTA C, Thomson K, Morgan I, Booth L, et al
Methylphenidate Inhibits the Development of Myopia by Altering Dopamine and Norepinephrine Reuptake.
Invest Ophthalmol Vis Sci. 2025;66:52.
PubMed Abstract available

VAN VOOREN E, Van Den Broeck F, Mahieu Q, Geens E, et al
RPE65 Variant p.(E519K) Causes a Novel Dominant Adult-Onset Maculopathy in 83 Affected Individuals.
Invest Ophthalmol Vis Sci. 2025;66:53.
PubMed Abstract available

TAN C, Wang X, Liu T, Liu L, et al
Ebbinghaus Illusion Distortions in Amblyopia: Impairments of Visual Size Processing and Interocular Integration.
Invest Ophthalmol Vis Sci. 2025;66:54.
PubMed Abstract available

WONG MW, Chong C, Sharma S, Phang LC, et al
Independent Effects of Axial Length and Intraocular Pressure on the Highly Myopic Optic Nerve Head.
Invest Ophthalmol Vis Sci. 2025;66:49.
PubMed Abstract available

ZHANG S, Sha Y, Xie Y, Hong J, et al
Kaempferol Alleviates Dry Eye Disease Via Modulation of the IDH3B/CCAR2/IKBKB Axis.
Invest Ophthalmol Vis Sci. 2025;66:50.
PubMed Abstract available

ZHOU T, Yang Z, Ni B, Zhou H, et al
Targeting RPE Senescence Via Suppressing IL-6/IL-6R Signaling for Treating Retinal Degenerative Diseases.
Invest Ophthalmol Vis Sci. 2025;66:44.
PubMed Abstract available

LIN YY, Warren E, Macklin BL, Ramirez L, et al
Endothelial-Pericyte Interactions Regulate Angiogenesis Via VEGFR2 Signaling During Retinal Development and Disease.
Invest Ophthalmol Vis Sci. 2025;66:45.
PubMed Abstract available

LI W, Li Y, Zhou Y, Liu Y, et al
Exon Skipping Therapy Restores Ciliary Function in USH2A-Related Retinal Degeneration.
Invest Ophthalmol Vis Sci. 2025;66:46.
PubMed Abstract available

JIANG L, Dan YS, Myles WE, Seah SHY, et al
Association Between Pigmentation Heritage and Susceptibility to Experimentally Induced Myopia: Crossbreeding Insights From Albino and Pigmented Guinea Pigs.
Invest Ophthalmol Vis Sci. 2025;66:47.
PubMed Abstract available

JIANG Y, Che Y, Zhang Y, Zhu X, et al
Small Extracellular Vesicle Treatment of Trabecular Meshwork Fibrosis: 2D/3D In Vitro and In Vivo Analyses.
Invest Ophthalmol Vis Sci. 2025;66:48.
PubMed Abstract available

CHEN M, Jiang Y, Yu H, Qi H, et al
Hydrogen Sulfide-Preconditioned Mesenchymal Stem Cells Attenuate Ferroptosis in Corneal Alkali Burn via the AMPK/Nrf2/HO-1 Pathway in an IL-10-Dependent Manner.
Invest Ophthalmol Vis Sci. 2025;66:58.
PubMed Abstract available

REITER GS, Birner K, Schrittwieser J, Hinterhuber L, et al
Deep-Learning-Based Analysis of Disease-Specific Structural Biomarkers on Retinal Sensitivity in Neovascular Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2025;66:68.
PubMed Abstract available

CHEN S, Yi Z, Zheng Y, Jiang Y, et al
Pigmentation Pattern of Iris and Fundus in 75 Chinese Families With GPR143-Associated Ocular Albinism.
Invest Ophthalmol Vis Sci. 2025;66:69.
PubMed Abstract available

YAMAMOTO M, Ash D, Sudhahar V, Zaidi SAH, et al
Novel Role of Copper Transporter CTR1 and Therapeutic Potential of Copper Chelators in Retinal Ischemia-Reperfusion Injury.
Invest Ophthalmol Vis Sci. 2025;66:70.
PubMed Abstract available

BLERSCH PR, Hoyer T, Alexiou C, Heindl LM, et al
Exploring the Interplay Between Hyperthermia and Cytotoxic Drugs in Ocular Melanoma Cell Lines: Implications and Variability in Treatment Efficiency.
Invest Ophthalmol Vis Sci. 2025;66:71.
PubMed Abstract available

DING X, Wang Y, Wan N, Wu X, et al
Elevated Nasal-Temporal Asymmetry of the Choroidal Vascular Index in Pathologically Myopic Eyes.
Invest Ophthalmol Vis Sci. 2025;66:66.
PubMed Abstract available

HUANG J, Jiang P, Chen B, Huang M, et al
PGC1A Restores Mitochondrial Health to Attenuate EMT During Lens Epithelial Fibrosis via Regulating TFAM.
Invest Ophthalmol Vis Sci. 2025;66:67.
PubMed Abstract available

CICINELLI MV, Pepe EM, Ramtohul P, Tombolini B, et al
Central Bouquet Hemorrhages in Retinal Vein Occlusion: A Distinct Pathway to Macular Atrophy.
Invest Ophthalmol Vis Sci. 2025;66:62.
PubMed Abstract available

CHEN M, Zhang X, Zeng Z, Fan C, et al
Targeting Bcl3/NF-kappaB p50 Pathway for Neuroinflammation Attenuation and RGCs Protection in Retinal Ischemia/Reperfusion Injury.
Invest Ophthalmol Vis Sci. 2025;66:63.
PubMed Abstract available

PATTAN HF, Murugan S, Shyam R, Tankam P, et al
Enabling In Vivo Longitudinal Evaluation of Descemet's Membrane Thickness in Wild-type and FECD Mice Using Self-Referenced Optical Coherence Microscopy.
Invest Ophthalmol Vis Sci. 2025;66:60.
PubMed Abstract available

PULASANI S, Zenkel M, Lammer R, Junemann A, et al
Establishment of an Advanced In Vitro Model for Pseudoexfoliation Syndrome and Glaucoma.
Invest Ophthalmol Vis Sci. 2025;66:61.
PubMed Abstract available

LING X, Zhang Y, Bui CHT, Chan HN, et al
Association Between Ocular Microbiomes of Children and Their Siblings and Parents.
Invest Ophthalmol Vis Sci. 2025;66:59.
PubMed Abstract available

August 2025

ZHANG XJ, Li Y, Zhang Y, Li X, et al
Association of Optic Nerve Head Metrics and Parapapillary Gamma Zone With Myopia Onset and Progression in Children: The Hong Kong Children Eye Study.
Invest Ophthalmol Vis Sci. 2025;66:1.
PubMed Abstract available

CHEN CY, Jhang JP, Lai YJ, Lin CW, et al
Clinical Manifestations and Ophthalmic Outcomes of Leukemic Retinopathy and Optic Neuropathy in Patients With Acute Leukemia.
Invest Ophthalmol Vis Sci. 2025;66:2.
PubMed Abstract available

BORA K, Liu CH, Kushwah N, Maurya M, et al
Genetic Loss of RORalpha Impairs Visual Function With Rod Bipolar Cell Degeneration In Mice.
Invest Ophthalmol Vis Sci. 2025;66:20.
PubMed Abstract available

GAO Y, Zhang Y, Gao Y, Mou K, et al
Adaptive Optics and Multimodal Retinal Imaging for Postoperative Evaluation in Patients With Epiretinal Membrane.
Invest Ophthalmol Vis Sci. 2025;66:22.
PubMed Abstract available

HUANG Z, Zhu T, Chen J, Qiu M, et al
CXCR4-Mediated Chemokine Signaling Orchestrates the Progression of Conjunctival Melanocytic Lesions.
Invest Ophthalmol Vis Sci. 2025;66:23.
PubMed Abstract available

SHAH SV, Brant AR, Ahmed A, Wireko Brobby NA, et al
Foveal Identification and Development in Prematurity-Implications on Zone Localization and Nutritional Supplementation.
Invest Ophthalmol Vis Sci. 2025;66:17.
PubMed Abstract available

ZHANG Q, Liu Z, Chen S, Wang Q, et al
Matrine Reduces Intraocular Pressure in Corticosteroid-Induced Ocular Hypertensive Mouse Eyes.
Invest Ophthalmol Vis Sci. 2025;66:18.
PubMed Abstract available

LIU Y, Tian X, Li C, Lin J, et al
Artesunate Treats Aspergillus fumigatus Keratitis by Inhibiting Fungal Activity and Activating Autophagy Pathway to Reduce Corneal Inflammation.
Invest Ophthalmol Vis Sci. 2025;66:19.
PubMed Abstract available

KHALAFALLAH MT, El Hamdaoui M, Fuchs PA, Samuels BC, et al
Early Peripapillary Choroidal Thinning during Myopia Development: A Potential Biomarker for Progressive Myopia Identified in Tree Shrews.
Invest Ophthalmol Vis Sci. 2025;66:11.
PubMed Abstract available

MERLE DA, Cuevas Villanueva V, Righetti G, Jung R, et al
Flavoprotein Fluorescence Imaging in Stargardt Disease: Linking Metabolic Stress to Structural Damage.
Invest Ophthalmol Vis Sci. 2025;66:12.
PubMed Abstract available

MAENO S, Yamashita A, Oie Y, Koto R, et al
Repeat Expansion and Somatic Instability in TCF4 in Patients With Fuchs Endothelial Corneal Dystrophy Identified by Small Pool PCR.
Invest Ophthalmol Vis Sci. 2025;66:14.
PubMed Abstract available

HUANG Z, Chen C, Meng J, Liu S, et al
Associations Among Sleep Duration, Sleep Quality, and Age-Related Ocular Diseases: Insights From Longitudinal and Mediation Analyses.
Invest Ophthalmol Vis Sci. 2025;66:15.
PubMed Abstract available

FRAGIOTTA S, Parravano M, Sacconi R, Polito MS, et al
Progression Patterns in Foveal-Sparing Geographic Atrophy With Double-Layer Sign Due to Neovascularization or Basal Laminar Deposits.
Invest Ophthalmol Vis Sci. 2025;66:16.
PubMed Abstract available

WU Y, Lu H, Chen C, Xiong J, et al
Polarization-Sensitive Optical Coherence Tomography Imaging of Posterior Staphyloma Edges in Eyes With High Myopia.
Invest Ophthalmol Vis Sci. 2025;66:6.
PubMed Abstract available

LIANG W, Huang L, Clayton JM, Nicholas SE, et al
Exploring the Therapeutic Potential of Salivary Exosomes in Corneal Epithelial Wound Healing.
Invest Ophthalmol Vis Sci. 2025;66:8.
PubMed Abstract available

REN Z, Li Z, Dou S, Zhao H, et al
Effects of Cholesterol Metabolism on Corneal Endothelial Dysfunction in Patients With Type 1 Diabetes.
Invest Ophthalmol Vis Sci. 2025;66:9.
PubMed Abstract available

KAUPER K, Nystuen A, Orecchio L, Gonzalez-Lopez E, et al
Long-Term Durability of Ciliary Neurotrophic Factor-Releasing Revakinagene Taroretcel-lwey in Individuals With Retinal Degenerative Disorders.
Invest Ophthalmol Vis Sci. 2025;66:3.
PubMed Abstract available

ZHU W, Hoover A, Wan L, Dai Y, et al
Retinal Neurovascular Signatures in Parkinson's Disease.
Invest Ophthalmol Vis Sci. 2025;66:10.
PubMed Abstract available

ALIO JL, Gauthier BR, Gomez Rosado JC, Alio Del Barrio JL, et al
Human Omental Mesothelial Cells Exhibit a Corneal Endothelial-Like Cell Phenotype for Tissue Engineering of a Corneal Endothelium Biomimetic.
Invest Ophthalmol Vis Sci. 2025;66:7.
PubMed Abstract available

Erratum in: Vps35 Deficiency Impairs Cdk5/p35 Degradation and Promotes the Hyperphosphorylation of Tau Protein in Retinal Ganglion Cells.
Invest Ophthalmol Vis Sci. 2025;66:4.
PubMed

Erratum in: Endothelial Yes-Associated Protein 1 Promotes Astrocyte Proliferation and Maturation via Cytoplasmic Leukemia Inhibitory Factor Secretion in Oxygen-Induced Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:5.
PubMed

ZHANG W, Zhang P, Pu Y, Chen Z, et al
DNA 5-Hydroxymethylcytosine Landscape and Transcriptional Profile Highlight the TUBB4B-Mediated Th17/Th1/Treg Imbalance in Behcet's Uveitis.
Invest Ophthalmol Vis Sci. 2025;66:28.
PubMed Abstract available

AMATO R, Canovai A, Melecchi A, De Fenza M, et al
Inhibiting The uPA/uPAR Pathway Affords Photoreceptor Resilience and Preserves Retinal Function in a Mouse Model of Retinitis Pigmentosa.
Invest Ophthalmol Vis Sci. 2025;66:29.
PubMed Abstract available

YIN S, Xu L, Yang K, Fan Q, et al
Genetic Epidemiological Analysis of the Keratoconus Genetic Model in the Chinese Keratoconus Cohort Study.
Invest Ophthalmol Vis Sci. 2025;66:30.
PubMed Abstract available

BIRCH DG, Duncan JL, Samarakoon L, Melia M, et al
Progression of Dark-Adapted Visual Fields Over 3 Years in the Rate of Progression in USH2A-Related Retinal Degeneration (RUSH2A) Study.
Invest Ophthalmol Vis Sci. 2025;66:27.
PubMed Abstract available

SHERMAN J, Burgstaler L, Li Y, Roehrich H, et al
The Role of Retinal Antigen-Presenting Cells in Spontaneous Retinal Autoimmunity.
Invest Ophthalmol Vis Sci. 2025;66:26.
PubMed Abstract available

MIAO H, Qu T, Huang Y, Fan S, et al
The Impact of Helicobacter pylori Infection on Retinal Nerve Fiber Layer and Macula.
Invest Ophthalmol Vis Sci. 2025;66:35.
PubMed Abstract available

CHEN C, Yang X, Jiang Z, Wang M, et al
Dual VEGF-Targeting Strategy Via AAV2-Delivered sFLT-1 and shVEGF for Retinal Neovascularization Therapy.
Invest Ophthalmol Vis Sci. 2025;66:37.
PubMed Abstract available

MATSUMURA N, Asaoka R, Fujino Y, Obana A, et al
The Relationship Between Macular Pigment Optical Volume and Visual Function in Glaucoma Patients.
Invest Ophthalmol Vis Sci. 2025;66:31.
PubMed Abstract available

CHAAR DL, Jiang C, Coomson SY, Duot M, et al
Whole Exome Sequencing Study Uncovers Novel Candidate Genes and Protein-Coding Variants for Cataract.
Invest Ophthalmol Vis Sci. 2025;66:32.
PubMed Abstract available

ANSARI G, Scharer N, Pfau K, Valmaggia P, et al
Evaluating the Progression of Retinal Sensitivity Loss in Geographic Atrophy Using Machine-Learning-Based Structure-Function Correlation (OMEGA 2).
Invest Ophthalmol Vis Sci. 2025;66:34.
PubMed Abstract available

RAMING K, Saltenberger I, Meinke J, Risseeuw S, et al
Intraocular Pressure After Anti-Vascular Endothelial Growth Factor Injection in Eyes With a Mineralized Bruch's Membrane Caused by Pseudoxanthoma Elasticum.
Invest Ophthalmol Vis Sci. 2025;66:25.
PubMed Abstract available

KAKIHARA S, Zhuang K, AbdelSalam M, Yamaguchi TC, et al
The Importance of Matching Optical Coherence Tomography Angiography Metrics to Diabetic Retinopathy Severity for Detecting Progression.
Invest Ophthalmol Vis Sci. 2025;66:49.
PubMed Abstract available

ROBERTS PA, Thomas CN, Bellamy Plaice G, Roberts JA, et al
Mathematical Models of Topically and Intravitreally Applied Ranibizumab.
Invest Ophthalmol Vis Sci. 2025;66:45.
PubMed Abstract available

UNLU EK, Marx-Rattner R, Klein KA, Dawson VL, et al
Differential Expression of the Synapse Regulatory Proteins Neurexins in Early Diabetic Retinal Disease.
Invest Ophthalmol Vis Sci. 2025;66:46.
PubMed Abstract available

PLAISANCIE J, Angee C, Erjavec E, Raymond-Letron I, et al
Insights Into the FOXE3 Transcriptional Network and Disease Mechanisms From the Investigation of a Regulatory Variant Driving Complex Microphthalmia.
Invest Ophthalmol Vis Sci. 2025;66:47.
PubMed Abstract available

MAI J, Reiter GS, Riedl S, Vogl WD, et al
Dynamics of the EZ/RPE Loss Ratio on OCT Over Time During Geographic Atrophy Progression and Treatment With Pegcetacoplan.
Invest Ophthalmol Vis Sci. 2025;66:48.
PubMed Abstract available

NETTESHEIM ER, Rowe AA, Yee T, Alshaikhsalama A, et al
Elevated PRDM13 Disrupts Photoreceptor Function and Survival in the Mammalian Retina.
Invest Ophthalmol Vis Sci. 2025;66:38.
PubMed Abstract available

YANG HS, Jo YH, Kim D, Choi S, et al
Yes-Associated Protein (YAP) Is Associated With Disease Severity and Visual Prognosis in Epiretinal Membrane.
Invest Ophthalmol Vis Sci. 2025;66:39.
PubMed Abstract available

SHEN LL, Zhang Y, Wong J, Foote KG, et al
Longitudinal Assessment of Cone Structure, Choriocapillaris, and Retinal Sensitivity in Choroideremia.
Invest Ophthalmol Vis Sci. 2025;66:40.
PubMed Abstract available

ZHANG X, Sun D, Liu T, Wang N, et al
Single-Cell Transcriptomics Reveals Effects of Long-Term Contact Lens Wearing on the Human Corneal Epithelium.
Invest Ophthalmol Vis Sci. 2025;66:59.
PubMed Abstract available

ZHANG Y, Wang R, Li Y, Zhu W, et al
Hyperglycemia-Reduced Platelet-Derived Growth Factor-BB Expression Impairs Corneal Wound Healing in Diabetic Mice.
Invest Ophthalmol Vis Sci. 2025;66:61.
PubMed Abstract available

ONISHI T, Yuasa T, Ueda N, Miyadai K, et al
The PERK-p38 MAPK Axis Drives Endoplasmic Reticulum Stress-Induced Apoptosis in Fuchs Endothelial Corneal Dystrophy.
Invest Ophthalmol Vis Sci. 2025;66:63.
PubMed Abstract available

GUPTA SK, Carkeet A, Read SA, Vincent SJ, et al
Contribution and Compensation Effects of Refracting Components to Ocular Aberrations in Keratoconus.
Invest Ophthalmol Vis Sci. 2025;66:64.
PubMed Abstract available

HAUPT HB, Nickerson JM, Boatright JH, Pardue MT, et al
Effects of Treadmill Exercise on Retinal Vascular Morphology, Function, and Circulating Immune Factors in a Mouse Model of Retinal Degeneration.
Invest Ophthalmol Vis Sci. 2025;66:65.
PubMed Abstract available

Erratum in: Calcitonin Gene-Related Peptide Regulates Specific Interferon-Stimulating Genes to Inhibit Apoptosis of Corneal Epithelial Cells in Dry Eye Disease.
Invest Ophthalmol Vis Sci. 2025;66:55.
PubMed

Retraction of: UBE2T/STAT3 Signaling Promotes the Proliferation and Tumorigenesis in Retinoblastoma.
Invest Ophthalmol Vis Sci. 2025;66:56.
PubMed

LUO Y, Yin J, Cao J, Xie B, et al
Targeted Delivery of CD34 Aptamer-Coupled Tocilizumab Microspheres for Effective Treatment of Thyroid-Associated Ophthalmopathy.
Invest Ophthalmol Vis Sci. 2025;66:57.
PubMed Abstract available

KAZEMI A, Roy Chowdhury U, Fautsch MP, Htoo TM, et al
Relationship Between Diurnal Variations of Episcleral Venous Pressure and Intraocular Pressure.
Invest Ophthalmol Vis Sci. 2025;66:44.
PubMed Abstract available

MAHROO OA
Expansion of The ABCA4-Associated Retinopathy Spectrum: Might Vitamin A Supplementation Have Contributed to a More Severe Phenotype?
Invest Ophthalmol Vis Sci. 2025;66:41.
PubMed

ABDUL R, Liu X, Choi K, Huang M, et al
Determination of the Population Frequency of Monoallelic and Biallelic Predicted Pathogenic RPE65 Variants in a Normal Database.
Invest Ophthalmol Vis Sci. 2025;66:73.
PubMed Abstract available

BRADLEY C, Yohannan J
Predicting the Structure-Function Relationship in Glaucoma Using a Physiological Model.
Invest Ophthalmol Vis Sci. 2025;66:75.
PubMed Abstract available

ZHANG K, Zhang Y, Wan X, Mou Y, et al
PFKFB3-Mediated Glycolytic Metabolic Reprogramming Regulates Inflammatory Response in Dry Eye Disease.
Invest Ophthalmol Vis Sci. 2025;66:76.
PubMed Abstract available

HUGHES MJ, Lamey T, Schiff ER, Lin S, et al
Sex Distributions in the Most Frequent Autosomal Genetic Causes of Retinitis Pigmentosa.
Invest Ophthalmol Vis Sci. 2025;66:77.
PubMed Abstract available

OLIVIERI C, Fai A, Bhutto IA, McLeod DS, et al
Retinal Vessel Changes in Geographic Atrophy in AMD: Insights From Imaging and Histology.
Invest Ophthalmol Vis Sci. 2025;66:69.
PubMed Abstract available

GUO Z, Feng H, Sun X, Yang L, et al
Celastrol Activates SIRT1/PGC-1alpha/Nrf2 Axis to Inhibit Oxidative Damage for Subconjunctival Fibrosis Alleviation.
Invest Ophthalmol Vis Sci. 2025;66:70.
PubMed Abstract available

YANG Y, Lou J, Tan S, Hou J, et al
Surgical Realignment Reverses Contrast Sensitivity Deficits in Children With Intermittent Exotropia: One-Year Results of a Cohort Study.
Invest Ophthalmol Vis Sci. 2025;66:71.
PubMed Abstract available

PENG Y, Wang Q, Xu J, Li Y, et al
P300 Promotes RUNX1 Transcription to Regulate Autophagy and Drive Corneal Neovascularization.
Invest Ophthalmol Vis Sci. 2025;66:66.
PubMed Abstract available

ROJAS-CARABALI W, Cifuentes-Gonzalez C, Utami A, Agarwal M, et al
Machine Learning for Predicting Recurrent Course in Uveitis Using Baseline Clinical Characteristics.
Invest Ophthalmol Vis Sci. 2025;66:67.
PubMed Abstract available

KUMAR R, Sinha NR, Gupta S, Tripathi R, et al
Open-Field Blast Injury Disrupts Corneal Gene Expression Linked to Ion Transport, Sensory Perception, and Neural Signaling.
Invest Ophthalmol Vis Sci. 2025;66:68.
PubMed Abstract available

LIN Z, Verma B, Zhu S, Zidan AA, et al
Calcitonin Gene-Related Peptide Ameliorates Experimental Dry Eye Disease.
Invest Ophthalmol Vis Sci. 2025;66:58.
PubMed Abstract available

CLARK R, He X, Nguyen TN, Bui TH, et al
Revisiting the Trans-Ancestry Genetic Correlation of Refractive Error.
Invest Ophthalmol Vis Sci. 2025;66:60.
PubMed Abstract available

MYLES WE, McFadden SA, Hoang QV
The Distribution of Spatial Contrast in Manmade Environments Produces Regional Visual Form Deprivation.
Invest Ophthalmol Vis Sci. 2025;66:42.
PubMed Abstract available

HSU CC, Lee LC, Chang HC, Lai CY, et al
Short-term Structural and Microvascular Ocular Changes Induced by Hypergravity Exposure During Human Centrifuge Training.
Invest Ophthalmol Vis Sci. 2025;66:72.
PubMed Abstract available

July 2025

MITAMURA M, Kase S, Endo H, Saito M, et al
Diabetes-Induced Dysregulation of Peripapillary and Macular Neurovascular Units.
Invest Ophthalmol Vis Sci. 2025;66:10.
PubMed Abstract available

STEPHENSON KAJ, Tse T, Hwang J, Kavetskyi A, et al
Quantitative Choroidal Analysis of Molecularly Characterized Retinitis Pigmentosa.
Invest Ophthalmol Vis Sci. 2025;66:11.
PubMed Abstract available

YU W, He Y, Qiu X, Yao Y, et al
Axial Length Dynamics and Safety of Occlusion Therapy in Pediatric Amblyopia: A Longitudinal Analysis.
Invest Ophthalmol Vis Sci. 2025;66:12.
PubMed Abstract available

ZHOU H, Zhou G, Yang Q, Niu J, et al
Evidence for M2 Muscarinic Receptor Antagonist Delay of Myopia Development Through Activation of Kir3.4 Channel in the Retina of Guinea Pigs.
Invest Ophthalmol Vis Sci. 2025;66:5.
PubMed Abstract available

JONES D, Chow A, Fadel D, Gonzalez Meijome JM, et al
IMI-Instrumentation for Myopia Management.
Invest Ophthalmol Vis Sci. 2025;66:7.
PubMed Abstract available

LEE M, Wood BJ, Jeong HH, Nam HW, et al
Retinal Angiogenesis in Methamphetamine Self-Administration Rats.
Invest Ophthalmol Vis Sci. 2025;66:8.
PubMed Abstract available

DE VRIES VA, van Garderen KA, Klaver CCW, Bos D, et al
The Effect of Carotid Atherosclerosis on the Risk for Open-Angle Glaucoma.
Invest Ophthalmol Vis Sci. 2025;66:9.
PubMed Abstract available

YII F, MacCormick IJC, Strang N, Bernabeu MO, et al
Fundus Refraction Offset as a Personalized Biomarker for 12-Year Risk of Retinal Detachment.
Invest Ophthalmol Vis Sci. 2025;66:1.
PubMed Abstract available

CLUTTER ED, Yang W, Han J, Kaplan N, et al
Inhibitor of DNA-Binding 3 Is a Novel Regulator of Limbal Epithelial Cell Migration Via the EphA2/Akt Signaling Pathway.
Invest Ophthalmol Vis Sci. 2025;66:2.
PubMed Abstract available

WONG WM, Robson AG, Baker RA, Arno G, et al
A Phenotypic Study of CRB1 Retinopathy Secondary to the Variant p.(Pro836Thr) Prevalent in Those of Black African Ancestry.
Invest Ophthalmol Vis Sci. 2025;66:3.
PubMed Abstract available

MARZBAN M, Diaz Torres S, Yu R, He W, et al
Polygenic Risk Prediction for Normal-Tension Glaucoma.
Invest Ophthalmol Vis Sci. 2025;66:4.
PubMed Abstract available

CUI X, Yi C, Liu J, Qi J, et al
The Gut Microbial System Responds to Retinal Injury and Modulates the Outcomes by Regulating Innate Immune Activation.
Invest Ophthalmol Vis Sci. 2025;66:6.
PubMed Abstract available

HOSEINI-YAZDI H, Carkeet A, Ahmed R, Ali F, et al
Relative Role of ON/OFF Pathways in Resolving and Adapting to Blur in Myopes and Emmetropes.
Invest Ophthalmol Vis Sci. 2025;66:29.
PubMed Abstract available

CHOMPOOWONG R, Wongphoom J, Kitkumthorn N, Saonanon P, et al
Elastin as a Novel Extracellular Matrix From Aberrant HDAC4 Expression in PDGF-BB-Induced Orbital Fibroblasts From Graves' Ophthalmopathy Patients.
Invest Ophthalmol Vis Sci. 2025;66:30.
PubMed Abstract available

SUN G, Emu M, Lin R, Gong J, et al
Interocular Differences in Retinal Curvature in Anisometropic Patients and Their Association With Myopic Degree Differences.
Invest Ophthalmol Vis Sci. 2025;66:31.
PubMed Abstract available

SASSEN SH, Sassen J, Sassmannshausen M, Goerdt L, et al
Early Photoreceptor Alterations After Retinal Detachment Repair.
Invest Ophthalmol Vis Sci. 2025;66:32.
PubMed Abstract available

PRESLEY W, Wang SQ, Guan B, Jeong SH, et al
FOXP4 Variants Are Associated With Plateau Iris and Angle Closure Glaucoma.
Invest Ophthalmol Vis Sci. 2025;66:23.
PubMed Abstract available

YAN B, Qiu J, Yang Y, Luo J, et al
Exosomal miRNA Profiling in Liquid Biopsy of Vitreous in Proliferative Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:24.
PubMed Abstract available

VEMULA S, Osman A, Yang X, Aronchik G, et al
Disrupted Motor Neuron and Neuromuscular Junction Development in an Albino Mice Model of Infantile Nystagmus.
Invest Ophthalmol Vis Sci. 2025;66:25.
PubMed Abstract available

YE G, Zhang Y, Huang S, Zhan J, et al
Choroidal Features of Cynomolgus Macaques in Relation to Age and Axial Length.
Invest Ophthalmol Vis Sci. 2025;66:17.
PubMed Abstract available

NOTOMI S, Wu G, Nagaoka T, Yotsumoto N, et al
Intravenous Sodium Iodate Administration Induces Macula-Specific RPE Damage and Rod-Dominant Apoptosis in the Cynomolgus Monkey.
Invest Ophthalmol Vis Sci. 2025;66:18.
PubMed Abstract available

ALHELALY M, Soylu C, Corradetti G, Corvi F, et al
In Vivo Characterization of Bruch's Membrane Breaks in Neovascular Age-Related Macular Degeneration Using High-Resolution Optical Coherence Tomography.
Invest Ophthalmol Vis Sci. 2025;66:19.
PubMed Abstract available

LI H, Peng H, Ma B, Sun X, et al
DJ-1 Promotes Diabetic Corneal Epithelial Wound Healing by Attenuating Hyperglycemia-Induced Oxidative Stress Through Inhibiting PTEN.
Invest Ophthalmol Vis Sci. 2025;66:20.
PubMed Abstract available

LIU T, Wang YX, Jonas JB, Hoang QV, et al
Gaze-Induced Optic Nerve Head Deformations Are Greater in High Myopia and Strains Increase With Axial Length.
Invest Ophthalmol Vis Sci. 2025;66:21.
PubMed Abstract available

DE VRIES VA, Szabo A, Vergroesen JE, Liu S, et al
Decoding the Cornea-Glaucoma Association: Evidence From Mendelian Randomization.
Invest Ophthalmol Vis Sci. 2025;66:22.
PubMed Abstract available

WANG J, Xu Z, Caldwell R
Activation of Sigma 1 Receptor Preserves Visual Function After Optic Nerve Injury.
Invest Ophthalmol Vis Sci. 2025;66:13.
PubMed Abstract available

VALSECCHI N, Mete M, Rapezzi G, Elifani M, et al
Hyperreflective Foci in the Ectopic Inner Foveal Layer of Advanced Idiopathic Epiretinal Membranes.
Invest Ophthalmol Vis Sci. 2025;66:14.
PubMed Abstract available

LEE T, Leung M, van Boxtel JJA, Boon MY, et al
The Effects of Refractive Imbalance on Binocular Vision Status, Reading Performance, and Vision-Related Reading Difficulty Symptoms in Expert Readers.
Invest Ophthalmol Vis Sci. 2025;66:15.
PubMed Abstract available

LEE EJ, Park DY, Kee C, Han JC, et al
Natural Course and Risk Factors of Glaucoma Development in the Untreated Fellow Eye in Unilateral Normal-Tension Glaucoma.
Invest Ophthalmol Vis Sci. 2025;66:16.
PubMed Abstract available

Erratum in: Assessment of Neuroprotective Effects of Glutamate Modulation on Glaucoma-Related Retinal Ganglion Cell Apoptosis In Vivo.
Invest Ophthalmol Vis Sci. 2025;66:33.
PubMed

Expression of Concern for: Assessment of Neuroprotective Effects of Glutamate Modulation on Glaucoma-Related Retinal Ganglion Cell Apoptosis In Vivo.
Invest Ophthalmol Vis Sci. 2025;66:34.
PubMed

Expression of Concern for: Retinal Ganglion Cell Apoptosis in Glaucoma Is Related to Intraocular Pressure and IOP-Induced Effects on Extracellular Matrix.
Invest Ophthalmol Vis Sci. 2025;66:35.
PubMed

HAO C, Li K, Wei Z, Radeen KR, et al
Transcriptomic Analysis of Human Lens Epithelium Tissue With and Without Cataract Surgery: Uncovering Novel Pathways of Post-Surgical Lens Epithelium Remodeling.
Invest Ophthalmol Vis Sci. 2025;66:28.
PubMed Abstract available

JEREMIC N, Esengonul M, Zarghami A, Pawloff M, et al
Superficial Retinal Intercapillary Oxygen Diffusion and Perfusion Deficit Alterations in Patients With Coronary Artery Disease.
Invest Ophthalmol Vis Sci. 2025;66:27.
PubMed Abstract available

LEE SH, Lee SJ, Koh A, Kim KH, et al
Efferocytosis by Macrophages Attenuates Inflammatory Responses Following Ultraviolet B-Induced Apoptosis in Corneal Stromal Cells.
Invest Ophthalmol Vis Sci. 2025;66:49.
PubMed Abstract available

CURCIO CA, Mullins RF, Stone EM, Goerdt L, et al
Genetic Associations of Rod- and Cone-Mediated Vision in Aging and Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2025;66:50.
PubMed Abstract available

GAO N, Me R, Singh S, Kumar A, et al
Hyperglycemia-Suppressed Acod1 Expression Contributes to Innate Immune Deficiency in Pseudomonas aeruginosa Keratitis.
Invest Ophthalmol Vis Sci. 2025;66:51.
PubMed Abstract available

YANG F, Lin J, Yang B, Hu A, et al
Inhibition of Endothelial HIF-1alpha by IDF-11774 Attenuates Retinal Neovascularization and Vascular Leakage.
Invest Ophthalmol Vis Sci. 2025;66:47.
PubMed Abstract available

PUTERA I, Swagemakers SMA, Nagtzaam NMA, van Holten-Neelen C, et al
Mycobacterium tuberculosis Infection of Retinal Endothelial Cells Induces Interferon Signaling Activation: Insights Into Tubercular Retinal Vasculitis.
Invest Ophthalmol Vis Sci. 2025;66:48.
PubMed Abstract available

SERGOTT RC, Carelli V, Newman NJ, Biousse V, et al
Predictors of Final Visual Outcome in Patients With Leber Hereditary Optic Neuropathy Treated With Lenadogene Nolparvovec Gene Therapy.
Invest Ophthalmol Vis Sci. 2025;66:42.
PubMed Abstract available

YI W, Wang H, Liu S, Zhang J, et al
6-Shogaol Alleviates Endotoxin-Induced Uveitis via Activation of HIF-1alpha to Regulate Inflammatory Responses and Endoplasmic Reticulum Stress.
Invest Ophthalmol Vis Sci. 2025;66:43.
PubMed Abstract available

DU Y, Feng L, Tang J, Qin X, et al
C5a-Induced Autophagy Dysfunction Promotes Choroidal Neovascularization Through the ROS-Inflammatory Pathway.
Invest Ophthalmol Vis Sci. 2025;66:44.
PubMed Abstract available

HU L, Ma J, Guo J, Liang H, et al
Mettl3 Regulates Lens Development by Promoting the Differentiation Processes of Secondary Fiber Cells.
Invest Ophthalmol Vis Sci. 2025;66:45.
PubMed Abstract available

CHEN XN, Zhang XJ, Zhang Y, Tang F, et al
Association of Attention-Deficit Hyperactivity Disorder With Myopia Among School Children.
Invest Ophthalmol Vis Sci. 2025;66:36.
PubMed Abstract available

WU Y, Liu X, Qian W, Yu Y, et al
Longitudinal Study of Changes in Retinal Curvature and its Relationship With Myopia Shift in Chinese Children.
Invest Ophthalmol Vis Sci. 2025;66:37.
PubMed Abstract available

BRUNT D, Legge GE, Fletcher DC, Xiong Y, et al
Perception of Straight Ahead With Vision, Hearing, and Proprioception by Individuals With Low Vision.
Invest Ophthalmol Vis Sci. 2025;66:38.
PubMed Abstract available

SHI S, Quagraine IM, Cakir GB, Murray J, et al
Dichoptic Visual Search at Varied Fellow Eye Contrasts and Visual Function Deficits in Amblyopia.
Invest Ophthalmol Vis Sci. 2025;66:39.
PubMed Abstract available

LIU S, Yi J, Lu S, Cao J, et al
The miR-320a/PRDX3 Axis Alleviates the Oxidative Stress and Fibrotic Alterations in Fibroblasts in Thyroid Eye Disease.
Invest Ophthalmol Vis Sci. 2025;66:41.
PubMed Abstract available

Erratum in: Childhood Myopia Part I: Contemporary Treatment Options.
Invest Ophthalmol Vis Sci. 2025;66:46.
PubMed

MORANDI SC, Uldry AC, Eldridge N, Kreuzer M, et al
Toward the Characterization of the Human Core Ocular Surface Microbiome.
Invest Ophthalmol Vis Sci. 2025;66:40.
PubMed Abstract available

GUPTA P, Thakur S, Wong CMJ, Man REK, et al
Glaucoma in Older Asians Aged 60 to 100 Years: Prevalence, Factors, Trends, and Projections (2024-2040).
Invest Ophthalmol Vis Sci. 2025;66:62.
PubMed Abstract available

KAAD SG, Korecki AJ, Simpson EM
Establishing Preclinical Quantitative Parameters for Future Assessment of Corneal and Retinal Therapeutics for Aniridia.
Invest Ophthalmol Vis Sci. 2025;66:60.
PubMed Abstract available

FLANDRIN O, Yang Y, Abboud S, Kumar NG, et al
TRPV1 Defends the Healthy Murine Cornea Against Staphylococcus aureus Adhesion Independently of Sensory Nerve Firing.
Invest Ophthalmol Vis Sci. 2025;66:61.
PubMed Abstract available

CHEN Z, Jiang D, Zheng Q, Xing S, et al
Association of Human Leukocyte Antigen Polymorphisms With Moderate-to-Severe Dry Eye With and Without Sjogren's Syndrome.
Invest Ophthalmol Vis Sci. 2025;66:57.
PubMed Abstract available

PICCOLO D, Sladen P, Guarascio R, Ziaka K, et al
Investigation of ABCA4 Missense Variants and Potential Small Molecule Rescue in Retinal Organoids.
Invest Ophthalmol Vis Sci. 2025;66:58.
PubMed Abstract available

SHEN R, Chan PP, Ling A, Chan NCY, et al
Risk Factors for Visual Field Progression in Primary Angle Closure Disease Over 10 Years: The CUPAL Study.
Invest Ophthalmol Vis Sci. 2025;66:59.
PubMed Abstract available

NERI G, Rebecchi C, Oakley JD, Olivieri C, et al
Deep Learning Model for Automated Classification of Macular Neovascularization Subtypes in AMD.
Invest Ophthalmol Vis Sci. 2025;66:55.
PubMed Abstract available

VOICHANSKI S, Bousquet E, Abraham N, Mafi M, et al
En Face OCT and the Phenotype Characterization of Drusen.
Invest Ophthalmol Vis Sci. 2025;66:52.
PubMed Abstract available

GORAI S, Faranda AP, Shihan MH, Wang Y, et al
LIRTS Viewer: A Web-Based Resource to View the Transcriptional Response of Lens Epithelial Cells to Injury.
Invest Ophthalmol Vis Sci. 2025;66:53.
PubMed Abstract available

KEMENES G, Rebenku I, Bajdik B, Vereb G, et al
Correlation of Multimodal Clinical Imaging With the Whole-Slide- and Superresolution-Based Immunohistological Structure of the Corneal Limbal Stroma.
Invest Ophthalmol Vis Sci. 2025;66:54.
PubMed Abstract available

SUGIOKA K, Nishida T, Yunoki M, Mukai N, et al
Interactive Effects of IL-1beta and TGF-beta on Urokinase-Type Plasminogen Activator and alpha-Smooth Muscle Actin Expression by Corneal Fibroblasts.
Invest Ophthalmol Vis Sci. 2025;66:56.
PubMed Abstract available

LIU R, Xin X, Ma S, Guo J, et al
Epac1 Inhibits Orbital Fibroblast Activation to Ameliorate Thyroid-Associated Orbitopathy-Like Features Through the JAK/STAT Signaling Pathway.
Invest Ophthalmol Vis Sci. 2025;66:68.
PubMed Abstract available

DAICH VARELA M, Romo-Aguas JC, Guarascio R, Ziaka K, et al
RHO-Associated Retinitis Pigmentosa: Genetics, Phenotype, Natural History, Functional Assays, and Animal Model - In Preparation for Clinical Trials.
Invest Ophthalmol Vis Sci. 2025;66:69.
PubMed Abstract available

YANG Y, Sze YH, Zhou H, Ko WWM, et al
Bidirectional Phosphorylation Changes in Opsins Associated With Early Myopia and Hyperopia Signal Regulation by Phosphoproteomics.
Invest Ophthalmol Vis Sci. 2025;66:70.
PubMed Abstract available

SHI Q, Wei Z, Pang J, Qudsi AI, et al
Achromobacter in the Conjunctival Sac Microbiota: Potential Association With Acanthamoeba Keratitis Related to Orthokeratology Lenses.
Invest Ophthalmol Vis Sci. 2025;66:71.
PubMed Abstract available

VERMA S, Montoya PAG, Sun M, Puri S, et al
Comparative Analysis of Age-Associated Changes in Meibum Composition, Distribution, and Function in Mice With Altered Hyaluronan Expression.
Invest Ophthalmol Vis Sci. 2025;66:72.
PubMed Abstract available

HONG X, Ding F, Zhang L, Lv R, et al
Calcitonin Gene-Related Peptide Regulates Specific Interferon-Stimulating Genes to Inhibit Apoptosis of Corneal Epithelial Cells in Dry Eye Disease.
Invest Ophthalmol Vis Sci. 2025;66:65.
PubMed Abstract available

SADEGHI E, Valsecchi N, Du K, Davis E, et al
Three-Dimensional Choroidal Vessel Analysis in Asymmetric Bilateral Age-Related Macular Degeneration: A Comparison of Active Neovascular AMD and Dry AMD Fellow Eyes.
Invest Ophthalmol Vis Sci. 2025;66:64.
PubMed Abstract available

SCHIKORA J, Nickel A, Bergert J, Hahnel R, et al
Complement C3 Activation in the Human Retinal Pigment Epithelium.
Invest Ophthalmol Vis Sci. 2025;66:67.
PubMed Abstract available

TAKAHASHI N, Tawarayama H, Chida Y, Takeda M, et al
ENO1 Dysfunction-Mediated Glycolytic Attenuation Exacerbates Oxidative Stress-Induced Retinal Ganglion Cell Death via Altered ATP Synthesis Pathway.
Invest Ophthalmol Vis Sci. 2025;66:63.
PubMed Abstract available

June 2025

BULLIMORE MA
How Have Animal Models Increased our Understanding of Human Myopia?
Invest Ophthalmol Vis Sci. 2025;66:2.
PubMed Abstract available

MARCOS S
Optical and Visual Diet in Myopia.
Invest Ophthalmol Vis Sci. 2025;66:3.
PubMed Abstract available

WILLIAMS KM, Hammond CJ
Perspectives on Genetic and Environmental Factors in Myopia, Its Prediction, and the Future Direction of Research.
Invest Ophthalmol Vis Sci. 2025;66:4.
PubMed Abstract available

HAREWOOD J, Contreras M, Huang K, Johnson S, et al
Access to Myopia Care in the United States-A Narrative Review.
Invest Ophthalmol Vis Sci. 2025;66:5.
PubMed Abstract available

KHANAL S, Tomiyama ES, Harrington SC
Childhood Myopia Part I: Contemporary Treatment Options.
Invest Ophthalmol Vis Sci. 2025;66:6.
PubMed Abstract available

KHANAL S, Tomiyama ES, Harrington SC
Childhood Myopia Part II: Treatment Mechanisms, Emerging Options, and Considerations.
Invest Ophthalmol Vis Sci. 2025;66:7.
PubMed Abstract available

WINTERS TM, Dorries MC
The Multifaceted Landscape of Myopia: Exploring Animal Models, the Optical and Visual Diet, Genetic and Environmental Factors, Access to Care, and Treatment Approaches.
Invest Ophthalmol Vis Sci. 2025;66:1.
PubMed

BA-ABBAD R, Peshenko IV, Varela MD, Lin S, et al
Clinical and Biochemical Characterization of Specific GUCY2D Alleles Associated With a Rare Form of Night Blindness.
Invest Ophthalmol Vis Sci. 2025;66:22.
PubMed Abstract available

QIN X, Sun J, Xu Y, Lu L, et al
Short-Chain Fatty Acids Are Potential Biomarkers of Immune Regulation in Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:23.
PubMed Abstract available

PFAFF A, Hubal A, Vos S, Bonilha V, et al
Disruption of Epidermal Growth Factor Receptor Signaling in RPE Cells Increases Resistance to Ocular Toxoplasmosis.
Invest Ophthalmol Vis Sci. 2025;66:11.
PubMed Abstract available

MATSUDA Y, Tanaka M, Zhao Y, Kakihara S, et al
Adrenomedullin-RAMP2 System Modulates Inflammation and Tissue Repair in Experimental Autoimmune Uveitis Via T-Cell and M2 Macrophage Regulation.
Invest Ophthalmol Vis Sci. 2025;66:12.
PubMed Abstract available

QU M, Bai X, Zhang M, Wu J, et al
Activation of Sympathetic Nervous System Drives Dry Eye Onset Via Norepinephrine-beta2-Adrenergic Receptor Signaling in Mice.
Invest Ophthalmol Vis Sci. 2025;66:13.
PubMed Abstract available

LIU M, Geng J, Jin S, Hu P, et al
Alterations of the Enteric Virome in Vogt-Koyanagi-Harada Disease.
Invest Ophthalmol Vis Sci. 2025;66:15.
PubMed Abstract available

JURKUTE N, Brennenstuhl H, Kustermann M, Van Haute L, et al
Biallelic NSUN3 Variants Cause Diverse Phenotypic Spectrum Disease: From Isolated Optic Atrophy to Severe Early-Onset Mitochondrial Disorder.
Invest Ophthalmol Vis Sci. 2025;66:17.
PubMed Abstract available

OYAMA Y, Ito S, Yuasa T, Ueda M, et al
Generation of a Mouse Model of Fuchs Endothelial Corneal Dystrophy by Knock-in of CTG Trinucleotide Repeat Expansion in the TCF4 Gene.
Invest Ophthalmol Vis Sci. 2025;66:18.
PubMed Abstract available

PANNEMAN DM, Hitti-Malin RJ, McKibbin M, de Bruijn SE, et al
Expansion of the ABCA4-Associated Retinopathy Spectrum: Severe Variants Can be Associated With Early-Onset Severe Retinal Dystrophy.
Invest Ophthalmol Vis Sci. 2025;66:19.
PubMed Abstract available

CHEN J, Zhuo X, Li Y, Zhu Y, et al
Cross-Tissue Transcriptome-Wide Association Study Identifies Novel Genes Associated With POAG.
Invest Ophthalmol Vis Sci. 2025;66:7.
PubMed Abstract available

ZHANG Y, Huang H, Zhong H, Zhang Y, et al
PRMT5 Regulates Senescence in Retinal Ganglion Cells by Targeting the Wnt/beta-Catenin Signaling Cascade.
Invest Ophthalmol Vis Sci. 2025;66:8.
PubMed Abstract available

YU X, Zhao H, Gao Y, Zhou T, et al
Genetic Spectrum and Genotype-Phenotype Correlations in a Chinese Cohort With Nanophthalmos With Secondary Angle-Closure Glaucoma.
Invest Ophthalmol Vis Sci. 2025;66:9.
PubMed Abstract available

BEN-ARZI A, Spector I, Keshet Y, Gal-Or O, et al
Anti-VEGF Agents Clearance Through the Aqueous Outflow Pathway in a Rat Model.
Invest Ophthalmol Vis Sci. 2025;66:1.
PubMed Abstract available

KLAASSEN I, Vader MJC, Aissa K, Tanck MWT, et al
Several Common Genetic Variations Associate With Functional or Anatomic Effects of Anti-VEGF Treatment in Conditions With Macular Edema.
Invest Ophthalmol Vis Sci. 2025;66:2.
PubMed Abstract available

GUPTA P, Man REK, Wong CMJ, Thakur S, et al
Prevalence and Patient-Centered, Health-Related, and Economic Impact of Under-Corrected Refractive Error in Community-Based Older Singaporean Adults: A Population-Based Study.
Invest Ophthalmol Vis Sci. 2025;66:3.
PubMed Abstract available

CHIANG CYN, Wang X, Gardiner SK, Buist M, et al
Impact of Optic Nerve Tortuosity, Globe Proptosis, and Size on Retinal Ganglion Cell Thickness Across General, Glaucoma, and Myopic Populations.
Invest Ophthalmol Vis Sci. 2025;66:4.
PubMed Abstract available

KAKIHARA S, Busza A, Yamaguchi TC, Fawzi AA, et al
Posterior Retinal Ischemia Correlates With Vision in Patients With Diabetes.
Invest Ophthalmol Vis Sci. 2025;66:5.
PubMed Abstract available

CRAWSHAW JR, Gaffney EA, Gertz M, Maini PK, et al
Modeling the Ocular Pharmacokinetics and Pharmacodynamics of Ranibizumab for Improved Understanding and Data Collection Strategies in Ocular Diseases.
Invest Ophthalmol Vis Sci. 2025;66:20.
PubMed Abstract available

LI D, Zhang X, Yang F, Jin X, et al
Cornea Nerves Can Identify Different Types of Parkinson's Disease.
Invest Ophthalmol Vis Sci. 2025;66:21.
PubMed Abstract available

LI Y, Xie F, Yang L, Wang X, et al
SLC6A6-Mediated Taurine Uptake Sustains Corneal Epithelial Stem/Progenitor Cell Function to Counteract Age-Related Dysfunction.
Invest Ophthalmol Vis Sci. 2025;66:25.
PubMed Abstract available

Erratum in: The Mechanosensitive Piezo1 Channel Mediates Mechanochemical Transmission in Myopic Eyes.
Invest Ophthalmol Vis Sci. 2025;66:16.
PubMed

SAEID S, Vinberg F, Koskelainen A
Impact of Second-Generation PDE 5 Inhibitor, Avanafil, on Retinal Function: Studies From Ex Vivo ERG.
Invest Ophthalmol Vis Sci. 2025;66:14.
PubMed Abstract available

ZHAO Y, Dong Y, Zheng Q, Zhao Y, et al
Fatty Acid Desaturase 1 Knockdown Promotes Wound Healing and Functional Recovery of the Corneal Epithelium in Diabetes.
Invest Ophthalmol Vis Sci. 2025;66:6.
PubMed Abstract available

ULLA L, Foti C, Arrigo A, Battaglia Parodi M, et al
Choroidal Hyperreflective Foci Represent a Common Finding Across Different Types of Macular Atrophy.
Invest Ophthalmol Vis Sci. 2025;66:42.
PubMed Abstract available

LEE SH, Koh A, Lee SJ, Lee H, et al
M2a Macrophage-Dominant Microenvironment in Inflammation Attenuation and Wound Healing of Human Corneal Endothelial Cells.
Invest Ophthalmol Vis Sci. 2025;66:35.
PubMed Abstract available

SASAKI M, Cheong KX, Chong CCY, Yu M, et al
Relationship of Choroidal Thickness With Age-Related Macular Degeneration in Asians: An Asian Eye Epidemiology Consortium Meta-Analysis.
Invest Ophthalmol Vis Sci. 2025;66:36.
PubMed Abstract available

MOLAEI H, Abbas Farishta R, Farivar R
Multi-Feature Mapping of Distortions in Amblyopia With Localized Sampling.
Invest Ophthalmol Vis Sci. 2025;66:37.
PubMed Abstract available

YANG H, Liu M, Song S, Xu Q, et al
HIF-1alpha Promotes Inflammatory Responses in Aspergillus Fumigatus Keratitis by Activating Pyroptosis Through Caspase-8/GSDMD Pathway.
Invest Ophthalmol Vis Sci. 2025;66:32.
PubMed Abstract available

DONG L, Zhou WD, Hu YB, Wei L, et al
Prevalence of Myopia and Axial Length Distribution in China: The Wuhu Children and Adolescents Eye Study.
Invest Ophthalmol Vis Sci. 2025;66:33.
PubMed Abstract available

WANG N, Li Y, Wang X, Yang L, et al
Corneal Sensory Denervation Causes Epithelial Ferroptosis and Delayed Healing in Mice.
Invest Ophthalmol Vis Sci. 2025;66:28.
PubMed Abstract available

SREEKUMAR PG, Nam MH, Hong E, Kannan R, et al
RAGE Is Essential for Subretinal Fibrosis in Laser-Induced Choroidal Neovascularization: Therapeutic Implications.
Invest Ophthalmol Vis Sci. 2025;66:30.
PubMed Abstract available

JOHNS KL, Faralli JA, Filla MS, Shah NS, et al
Age-Related Dysregulation of alpha5beta1 and alphavbeta3 Integrin Activity Alters Contractile Properties of Trabecular Meshwork Cells.
Invest Ophthalmol Vis Sci. 2025;66:31.
PubMed Abstract available

Erratum in: Ferroptosis Contributes to Retinal Ganglion Cell Loss in GLAST Knockout Mouse Model of Normal Tension Glaucoma.
Invest Ophthalmol Vis Sci. 2025;66:44.
PubMed

Erratum in: Behind the Scenes at Investigative Ophthalmology & Visual Science.
Invest Ophthalmol Vis Sci. 2025;66:45.
PubMed

DRACHMANN J, Petersen L, Jeppesen SK, Bek T, et al
Systemic Hypoxia Increases Retinal Blood Flow but Reduces the Oxygen Saturation Less in Peripheral Than in Macular Vessels in Normal Persons.
Invest Ophthalmol Vis Sci. 2025;66:43.
PubMed Abstract available

FLITCROFT I, Bullimore MA, Gifford KL, Jonas JB, et al
Myopia Correction, Myopia Control and Myopia Management: Definitions and Recommended Usage.
Invest Ophthalmol Vis Sci. 2025;66:41.
PubMed

Erratum in: Ocular Surface Involvements in the Development of Sjogren's Syndrome-Associated Dry Eye in the IL14alpha Transgenic Mouse.
Invest Ophthalmol Vis Sci. 2025;66:39.
PubMed

LANNING EP, Branch MJ, Harding P, Margari M, et al
Characterization of Bruch's Membrane Formation in Human Fetal Retina and De Novo Membrane Synthesis by hPSC-Derived Retinal Pigment Epithelium.
Invest Ophthalmol Vis Sci. 2025;66:40.
PubMed Abstract available

Erratum in: A Novel AAV Capsid-Mediated RS1 Gene Therapy Restored Retinal Function to Wild-Type Levels in Rs1R213W Mouse Model.
Invest Ophthalmol Vis Sci. 2025;66:29.
PubMed

WEI ZHANG S, Guo J, Chen Y, Liu J, et al
Associations Between Myopia and Brain Volumes: An Observational and Genetic Analysis.
Invest Ophthalmol Vis Sci. 2025;66:57.
PubMed Abstract available

MIRANDA SW, Andre C, Bispo PJM, Gilmore MS, et al
Whole Genome Analysis of Ocular Pseudomonas aeruginosa Isolates Reveals Genetic Diversity.
Invest Ophthalmol Vis Sci. 2025;66:58.
PubMed Abstract available

WANG J, Yin Z, Yang J, Sun S, et al
BCAT1 Activation Reprograms Branched-Chain Amino Acid Metabolism and Epigenetically Promotes Inflammation in Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:59.
PubMed Abstract available

KAN J, Song S, Liu M, Xu Q, et al
Pyroptosis Mediated by ROS/Caspase-3/GSDME Pathway in Aspergillus fumigatus-Induced Fungal Keratitis.
Invest Ophthalmol Vis Sci. 2025;66:52.
PubMed Abstract available

LI Y, Yang B, Chen Q, Zhou Y, et al
RIPK3-Mediated Necroptosis Drives Macrophage Infiltration and Corneal Neovascularization After Alkali Burn.
Invest Ophthalmol Vis Sci. 2025;66:54.
PubMed Abstract available

KERMANY DS, Poon W, Bawiskar A, Nehra N, et al
Identifying Retinal Features Using a Self-Configuring CNN for Clinical Intervention.
Invest Ophthalmol Vis Sci. 2025;66:55.
PubMed Abstract available

JI R, Ishikawa K, Tan W, Mori K, et al
Liposome Encapsulation Enhances Ripasudil Therapeutic Efficacy Against Proliferative Vitreoretinal Diseases: Implications in Advanced Ocular Treatment.
Invest Ophthalmol Vis Sci. 2025;66:56.
PubMed Abstract available

YANG R, Zong T, Wang N, Wang F, et al
NR4A1 Alleviates Subretinal Fibrosis by Inhibiting Macrophage to Myofibroblast Transition.
Invest Ophthalmol Vis Sci. 2025;66:47.
PubMed Abstract available

YANG YC, Tsai DC, Fang SY, Yang HY, et al
Myopia Development During Transition From Kindergarten to Early Grades in Elementary School: Population-Based Evidence From an Epidemic Area in Taiwan.
Invest Ophthalmol Vis Sci. 2025;66:48.
PubMed Abstract available

GARREIS F, Adelung S, Schicht M, Hampel U, et al
Calcium-Dependent Regulation of Desmosomal Proteins in Human Meibomian Gland Epithelial Cells.
Invest Ophthalmol Vis Sci. 2025;66:49.
PubMed Abstract available

UWACU TDF, Bhattacharyya S, Saunders KJ, Little JA, et al
Hyperopic Eyes Are Structurally More Dynamic Than Myopic Eyes During Accommodation: An In Vivo Investigation.
Invest Ophthalmol Vis Sci. 2025;66:51.
PubMed Abstract available

SWAN J, Toomey CB, Bergstrand M, Cuello HA, et al
The Sialome of the Retina, Alteration in Age-Related Macular Degeneration Pathology, and Potential Impacts on Complement Factor H.
Invest Ophthalmol Vis Sci. 2025;66:81.
PubMed Abstract available

MARTINS MELO I, Messinger JD, Curcio CA, Muni RH, et al
Histological Assessment of Foveal Mechanical Instability and Potential Implications for Macular Diseases.
Invest Ophthalmol Vis Sci. 2025;66:82.
PubMed Abstract available

PEI X, Xuan S, Yang J, Ba M, et al
Plin2 Coordinates Immune and Metabolic Reprogramming in Lacrimal Gland Aging.
Invest Ophthalmol Vis Sci. 2025;66:79.
PubMed Abstract available

BANDE MF, Pineiro C, Lago-Baameiro N, Silva-Rodriguez P, et al
Serum gp100 as an Independent Prognostic Biomarker in Early-Stage Uveal Melanoma.
Invest Ophthalmol Vis Sci. 2025;66:80.
PubMed Abstract available

IKEDA SI, Lee D, Chen J, Fukuda S, et al
Antibiotics-Induced Gut Microbiome Dysbiosis Affects Susceptibility to Minus Lens-Induced Myopia in Mice.
Invest Ophthalmol Vis Sci. 2025;66:76.
PubMed Abstract available

HUANG J, Chang Z, Liu L, Lai C, et al
Maraviroc Prevents Optic Nerve Injury-Induced Retinal Ganglion Cell Apoptosis by Modulating the CCL5/CCR5/CTSS Axis.
Invest Ophthalmol Vis Sci. 2025;66:77.
PubMed Abstract available

HYDE RA, Park JC, McAnany JJ
Increment Thresholds in Retinitis Pigmentosa: Association With Retinal Thickness.
Invest Ophthalmol Vis Sci. 2025;66:78.
PubMed Abstract available

ZHA Z, Li J, Xie S, Shang X, et al
FGF10 Protects the Corneal Epithelium From Dry Eye-Induced Oxidative and ER Stress Via Upregulation of SLC7A11.
Invest Ophthalmol Vis Sci. 2025;66:72.
PubMed Abstract available

TSAI CY, Huang WL, Yang SC, Huang BD, et al
Human Platelet Lysate Treatment for Exposure Keratopathy: An In Vivo Confocal Microscopy and Anterior Segment OCT Study.
Invest Ophthalmol Vis Sci. 2025;66:73.
PubMed Abstract available

ZHOU N, Yoshida T, Sugisawa K, Yoshimoto S, et al
Interplay Between gamma-Zone Peripapillary Atrophy and Optic Disc Parameters in Central Visual Field Impairment in Highly Myopic Eyes.
Invest Ophthalmol Vis Sci. 2025;66:74.
PubMed Abstract available

HANG A, Shao A, Shea M, Roux MJ, et al
Ocular Phenotyping of Knockout Mice Identifies Genes Associated With Late Adult Retinal Phenotypes.
Invest Ophthalmol Vis Sci. 2025;66:64.
PubMed Abstract available

FENG ZX, Zhao J, D'Souza D, Zhang N, et al
Optic Nerve Invasion in Retinoblastoma: Impact of Eye Salvage and Adjuvant Chemotherapy.
Invest Ophthalmol Vis Sci. 2025;66:65.
PubMed Abstract available

MADJEDI KM, Stuart KV, Yin GS, Luben RN, et al
The Association of Muscle-Related Factors With Glaucoma and Related Traits in a Large United Kingdom Population.
Invest Ophthalmol Vis Sci. 2025;66:66.
PubMed Abstract available

BAO X, Xu Z, Wang X, Zhang T, et al
Three-Dimensional Culture of Orbital Fibroblasts From Thyroid Eye Disease Induce In Vivo-Like Tissue Remodeling and Fibrosis.
Invest Ophthalmol Vis Sci. 2025;66:67.
PubMed Abstract available

SOUVEREIN EA, Oak S, Fouladian Z, Reid MW, et al
Small-Molecule Inhibition of the Hippo Pathway Induces Regeneration of Retinal Pigment Epithelium.
Invest Ophthalmol Vis Sci. 2025;66:69.
PubMed Abstract available

OSADA H, Nishimura T, Mitsunaga M, Saruta M, et al
Evaluation of Anti-VEGFR2 Specific Photoimmunotherapy for Targeted Regression of Neovascularization in an AMD Model.
Invest Ophthalmol Vis Sci. 2025;66:70.
PubMed Abstract available

TRAN E, Rakesh M, Li G, Freeman EE, et al
Does the Association Between Eye Disease and Cognitive Function Vary by Genetic Risk of Cognitive Decline? An Analysis of Hospital Data With Replication in the Canadian Longitudinal Study on Aging.
Invest Ophthalmol Vis Sci. 2025;66:71.
PubMed Abstract available

FAN Z, Yang S, Lu X, Zhang S, et al
Alteration of Tear Metabolomics Profiling in Infants With Retinopathy of Prematurity.
Invest Ophthalmol Vis Sci. 2025;66:61.
PubMed Abstract available

JONAS JB, Panda-Jonas S, Milea D, Lamirel C, et al
Peripapillary Hyperreflective Ovoid Mass-Like Structures: Prevalence and Associations in the Adult Population of the Beijing Eye Study.
Invest Ophthalmol Vis Sci. 2025;66:63.
PubMed Abstract available

Erratum in: Dysregulation of Autophagy Occurs During Congenital Cataract Development in betaA3DeltaG91 Mice.
Invest Ophthalmol Vis Sci. 2025;66:75.
PubMed

MILICEVIC N, Sandu C, Challet E, Ihalainen TO, et al
Circadian Rhythms in Murine Ocular Tissues Including Sclera Are Affected by Neurobasal A Medium Preincubation and Mouse Strain, but Not Sex.
Invest Ophthalmol Vis Sci. 2025;66:62.
PubMed Abstract available

DE ABREU J, Paillisser A, Berquet F, Hogg S, et al
Changes in Retinal Vasculature Phenotype and Choroidal Blood Flow at High Altitude in Healthy Lowlanders.
Invest Ophthalmol Vis Sci. 2025;66:50.
PubMed Abstract available

May 2025

FEI C, Dong MR, Byars S, Shah JS, et al
RNA-Seq Study of Human Lens Epithelial Cells: Differentially Expressed Genes and Pathways in Steroid, Uveitic, Post-Vitrectomy, and Senile Cataracts.
Invest Ophthalmol Vis Sci. 2025;66:4.
PubMed Abstract available

WALKER MK, Berntsen DA, Robich ML, Fenton RL, et al
Three-Year Change in Subfoveal Choroidal Thickness and Area With Multifocal Contact Lens Wear in the Bifocal Lenses in Nearsighted Kids (BLINK) Study.
Invest Ophthalmol Vis Sci. 2025;66:5.
PubMed Abstract available

ZHAO Y, Ge Z, Guo T, Liu H, et al
Complement C3/C3aR Signaling Pathway Inhibition Ameliorates Retinal Damage in Experimental Retinal Vein Occlusion.
Invest Ophthalmol Vis Sci. 2025;66:2.
PubMed Abstract available

CHO D, Choi SH, Yoon JS, Ko J, et al
Nicotinamide N-Methyltransferase in the Inflammatory Pathogenesis of Graves' Orbitopathy.
Invest Ophthalmol Vis Sci. 2025;66:3.
PubMed Abstract available

YOSHIOKA H, Ueta M, Yokoo S, Yokoi N, et al
Retinoic Acid Receptor Alpha- and Beta-Mediated Signaling Regulates Conjunctival Epithelial Cell Keratinization.
Invest Ophthalmol Vis Sci. 2025;66:6.
PubMed Abstract available

KOLAWOLE OU, Bensinger E, Wong J, Rinella N, et al
High Resolution Imaging and Fixation Analysis of Eccentric Preferred Retinal Loci in Macular Diseases.
Invest Ophthalmol Vis Sci. 2025;66:18.
PubMed Abstract available

WEN B, Li H, Tao H, Ren H, et al
Regulatory Effects of the Wnt7b/beta-Catenin/MMP-2 Signaling Pathway on Scleral Stiffness in Guinea Pigs With Form-Deprivation Myopia.
Invest Ophthalmol Vis Sci. 2025;66:19.
PubMed Abstract available

MACHIDA A, Suzuki K, Nakayama T, Miyagi S, et al
Glucagon-Like Peptide 1 Receptor Agonist Stimulation Inhibits Laser-Induced Choroidal Neovascularization by Suppressing Intraocular Inflammation.
Invest Ophthalmol Vis Sci. 2025;66:15.
PubMed Abstract available

HUANG W, Liu Y, Li J, Gao Y, et al
Endoplasmic Reticulum Stress Drives Neuroinflammation Through Lipocalin 2 Upregulation in Retinal Microglia After Optic Nerve Injury.
Invest Ophthalmol Vis Sci. 2025;66:12.
PubMed Abstract available

ZHOU X, Wu Y, Zhang Y, Chu B, et al
Targeting alpha7 Nicotinic Acetylcholine Receptor for Modulating the Neuroinflammation of Dry Eye Disease Via Macrophages.
Invest Ophthalmol Vis Sci. 2025;66:13.
PubMed Abstract available

THOMSEN AK, Steffensen MA, Nielsen AT, Vorum H, et al
Chemokine System Changes Drive Age-Related Macular Degeneration and Influence Treatment Outcomes.
Invest Ophthalmol Vis Sci. 2025;66:14.
PubMed Abstract available

YOON EG, Nam KT, Choi M, Choi KE, et al
Aqueous Humor Levels of Vascular Endothelial Growth Factor in Patients With Dry Age-Related Macular Degeneration and Subretinal Drusenoid Deposits.
Invest Ophthalmol Vis Sci. 2025;66:10.
PubMed Abstract available

LONGORIA-GONZALEZ L, Coburn PS, Astley R, Chen Y, et al
Contribution of Leukocidin ED to the Pathogenesis of Staphylococcus aureus Endophthalmitis.
Invest Ophthalmol Vis Sci. 2025;66:11.
PubMed Abstract available

BRIERE A, Vo P, Yang B, Adams D, et al
Systematic Ocular Phenotyping of Knockout Mouse Lines Identifies Genes Associated With Age-Related Corneal Dystrophies.
Invest Ophthalmol Vis Sci. 2025;66:7.
PubMed Abstract available

HAZEN P, Khadka NK, Mainali L
Cholesterol and Q147E Deamidation Modulates alphaA-Crystallin Membrane Binding Elucidating Protective Role of Lens Membrane Composition Changes With Aging.
Invest Ophthalmol Vis Sci. 2025;66:8.
PubMed Abstract available

ZHU Q, Shayan M, Huckfeldt RM, Chen Y, et al
Comparative Efficacy of Interleukin-7 and -15 Blockade in Alleviating Experimental Chronic Uveitis and Suppressing Pathogenic Memory CD4+ T Cells.
Invest Ophthalmol Vis Sci. 2025;66:9.
PubMed Abstract available

LIU X, Zuo H, Wu C, Li N, et al
Muscone Attenuates Uveitis Through the PI3K/AKT Signaling Pathway.
Invest Ophthalmol Vis Sci. 2025;66:21.
PubMed Abstract available

Erratum in: Enlarged Blind Spot Linked to Gamma Zone and Peripapillary Hyperreflective Ovoid Mass-Like Structures in Non-Pathological Highly Myopic Eyes.
Invest Ophthalmol Vis Sci. 2025;66:16.
PubMed

BAO X, Xu Z, Wang X, Zhang T, et al
Canonical and Truncated Transglutaminase-2 Drive TGF-beta1 Autocrine Loop to Induce Fibrosis in Graves' Orbitopathy.
Invest Ophthalmol Vis Sci. 2025;66:22.
PubMed Abstract available

ZHANG R, Liang L, Liao K, Zeng H, et al
Autophagy Impairment-Derived SQSTM1 Accumulation Promotes Ferroptosis in Corneal Epithelial Cells Through ACSL4 in Dry Eye.
Invest Ophthalmol Vis Sci. 2025;66:23.
PubMed Abstract available

CHEN X, Li C, Li J, Guo Z, et al
LncRNA HOTAIR Interaction With WTAP Promotes m6A Methyltransferase Complex Assembly and Posterior Capsule Opacification Formation by Increasing THBS1.
Invest Ophthalmol Vis Sci. 2025;66:20.
PubMed Abstract available

LI D, Zou B, Hu Q, Zhang X, et al
Single-Cell RNA Sequencing of the Primary Visual Cortex in Mice With Optic Nerve Injury.
Invest Ophthalmol Vis Sci. 2025;66:31.
PubMed Abstract available

RODRIGUEZ-MARTINEZ AC, Tailor-Hamblin VK, Higgins BE, Jones PR, et al
Elevated Visual Crowding in CRB1-Associated Retinopathies: Understanding Functional Visual Deficits Using Child-Friendly Computerized Testing.
Invest Ophthalmol Vis Sci. 2025;66:32.
PubMed Abstract available

LI D, Duan H, Wang X, Lin Z, et al
Assessment of Corneal Endothelial Barrier Function Based on "Y-Junctions": A Finite Element Analysis.
Invest Ophthalmol Vis Sci. 2025;66:33.
PubMed Abstract available

WANG Z, Friedrich MG, Truscott RJW, Schey KL, et al
Identification of Age- and Cataract-Related Changes in High-Density Lens Protein Aggregates.
Invest Ophthalmol Vis Sci. 2025;66:34.
PubMed Abstract available

WANG X, Chen B, Chen J, Huang M, et al
PERK Regulates Epithelial-Mesenchymal Transition Through Autophagy and Lipid Metabolism in Lens Epithelial Cells.
Invest Ophthalmol Vis Sci. 2025;66:35.
PubMed Abstract available

MONU M, Kumar B, Asfiya R, Nassiri N, et al
Metabolomic Profiling of Aqueous Humor From Glaucoma Patients Identifies Metabolites With Anti-Inflammatory and Neuroprotective Potential in Mice.
Invest Ophthalmol Vis Sci. 2025;66:28.
PubMed Abstract available

LUO T, Li C, Zhou L, Sun H, et al
Protein Acetylation in Age-Related Macular Degeneration: Mechanisms, Roles, and Therapeutic Perspectives.
Invest Ophthalmol Vis Sci. 2025;66:30.
PubMed Abstract available

NIE J, Tang J, Zhang Z, Sun H, et al
SOX4 as a Key Oncogene Driving Tumor Invasion in Retinoblastoma.
Invest Ophthalmol Vis Sci. 2025;66:24.
PubMed Abstract available

LIN W, He Z, Zhou S, Weng L, et al
Monocular Contrast Sensitivity Visual Perceptual Learning Rebalances Adult Amblyopes' Two Eyes.
Invest Ophthalmol Vis Sci. 2025;66:25.
PubMed Abstract available

YE H, Feng Y, Xiang W, Lin Z, et al
Ferroptosis Contributes to Retinal Ganglion Cell Loss in GLAST Knockout Mouse Model of Normal Tension Glaucoma.
Invest Ophthalmol Vis Sci. 2025;66:26.
PubMed Abstract available

SHETTY N, Mahendradas P, Kannan R, Das S, et al
Metabolomic Profiling of Ocular Fluid Identifies Host Response Factors for Risk Stratification in Bacterial Endophthalmitis.
Invest Ophthalmol Vis Sci. 2025;66:27.
PubMed Abstract available

LI Y, Liu Y
Recent Advances in Stem Cells of Corneal Epithelia.
Invest Ophthalmol Vis Sci. 2025;66:45.
PubMed Abstract available

GUAN Z, Jiao S, Yang X, Liu S, et al
Potential Application of Bendazac L-Lysine for Controlling Myopia Progression, as Demonstrated in Two Experimental Guinea Pig Myopia Models.
Invest Ophthalmol Vis Sci. 2025;66:46.
PubMed Abstract available

DHUNGEL D, Bex PJ, McCullough A, Marin-Franch I, et al
Peripheral Blur Perception in Young Children at Low Risk or High Risk of Myopia: Longitudinal Data.
Invest Ophthalmol Vis Sci. 2025;66:40.
PubMed Abstract available

LOPEZ-LOPEZ M, Regueiro U, Bravo S, Pena C, et al
Tear Proteomic Analysis From Offspring of Keratoconus Patients: New Insights Into Corneal Biomechanical Weakness and Disease Risk Stages.
Invest Ophthalmol Vis Sci. 2025;66:41.
PubMed Abstract available

GONG J, Chan KS, Rajesh A, Droho S, et al
Adrb2 Expression in Ocular-Infiltrating Macrophages Is Necessary for Interleukin-6 Expression and Choroidal Neovascularization.
Invest Ophthalmol Vis Sci. 2025;66:43.
PubMed Abstract available

OWUSU-ANSAH K, Pham DL, Strong BC, Liberoni L, et al
Peptide Lv Deficiency Adversely Impacts the Structural and Functional Integrity of the Neural Retina.
Invest Ophthalmol Vis Sci. 2025;66:37.
PubMed Abstract available

TAN RKY, Tun TA, Braeu FA, Perera SA, et al
Iris Crypts Could Reduce the Chance of Angle Closure: A Computational Biomechanics Study Derived From Clinical and Human Iris Data.
Invest Ophthalmol Vis Sci. 2025;66:36.
PubMed Abstract available

HINDSO TG, Bjerrum CW, Nissen K, Sjol MB, et al
Validation of Four Prognostic Models for Metastatic Posterior Uveal Melanoma in a Danish Cohort.
Invest Ophthalmol Vis Sci. 2025;66:38.
PubMed Abstract available

PAREKH B, Peck-Dimit N, Duncan JL, Samarakoon L, et al
Functional Vision Assessment Over 4 Years in USH2A Using the Veteran Affairs Low-Vision Visual Functioning Questionnaire.
Invest Ophthalmol Vis Sci. 2025;66:39.
PubMed Abstract available

April 2025

HAO C, Fan E, Wei Z, Radeen KR, et al
Elevated Inflammatory Cytokines Persist in the Aqueous Humor Years After Cataract Surgery.
Invest Ophthalmol Vis Sci. 2025;66:12.
PubMed Abstract available

MANDAL S, Sucharita S, Deshmukh V, Priyadarshini SR, et al
Histopathological Evaluation of Corneal Tissues in Microsporidia Stromal Keratitis.
Invest Ophthalmol Vis Sci. 2025;66:9.
PubMed Abstract available

CHANG L, Song F, Qu S, Cao H, et al
In Vivo Brillouin Analysis of Lens Nucleus and Cortex in Adult Myopic Eyes and Their Correlation With Accommodation.
Invest Ophthalmol Vis Sci. 2025;66:6.
PubMed Abstract available

ANTROPOLI A, Bianco L, Zanlonghi X, Benadji A, et al
Phenotypic and Genotypic Characterization of RP1L1-Associated Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:7.
PubMed Abstract available

ZHOU C, Zhou J, Min SH
Temporal Frequency Modulation of Binocular Balance in Normal and Amblyopic Vision.
Invest Ophthalmol Vis Sci. 2025;66:8.
PubMed Abstract available

KOMAI S, Quiroga-Garza ME, Ruiz-Lozano RE, Azar NS, et al
Deep Corneal Nerve Plexus Selective Damage in Persistent Neurotrophic Corneal Epithelial Defects Detected by In Vivo Multiphoton Confocal Microscopy.
Invest Ophthalmol Vis Sci. 2025;66:1.
PubMed Abstract available

ONG JX, Lee HJ, Decker NL, Castellanos-Canales D, et al
Volumetric Measures of Capillary Nonperfusion on Optical Coherence Tomography Angiography Detect Early Ischemia in Diabetes Without Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:2.
PubMed Abstract available

ALABDULKADER B, Almustanyir A, Alsalem N, Almutleb E, et al
Arabic Reading Performance With a Chromatic Acuity Chart.
Invest Ophthalmol Vis Sci. 2025;66:3.
PubMed Abstract available

WU Q, Hu R, Liu Q, Li F, et al
Enlarged Blind Spot Linked to Gamma Zone and Peripapillary Hyperreflective Ovoid Mass-Like Structures in Non-Pathological Highly Myopic Eyes.
Invest Ophthalmol Vis Sci. 2025;66:5.
PubMed Abstract available

Erratum in: Dioleoylphosphatidylglycerol Accelerates Corneal Epithelial Wound Healing.
Invest Ophthalmol Vis Sci. 2025;66:11.
PubMed

Erratum in: Porcine Sub-Retinal Pigment Epithelium Deposits: A Model for Dry Age-Related Macular Degeneration With Comparison to Human Drusen.
Invest Ophthalmol Vis Sci. 2025;66:10.
PubMed

GIALLONGO S, Bellia F, Russo A, Fallico M, et al
Comparative Evaluation of Cigarette Smoke and a Heated Tobacco Product on Corneal Oxidative Stress in an Air/Liquid Interface Model.
Invest Ophthalmol Vis Sci. 2025;66:4.
PubMed Abstract available

CHEN YR, Jiang SQ, Liu XY, Zhang JY, et al
Temporal Contour Integration Deficits in Children With Amblyopia.
Invest Ophthalmol Vis Sci. 2025;66:27.
PubMed Abstract available

OBUKHOVA TS, Stroganova TA, Artemenko AR, Petrokovskaia AV, et al
Directional Motion Sensitivity in Visual Snow Syndrome and Its Relation to Trailing-Type Palinopsia.
Invest Ophthalmol Vis Sci. 2025;66:24.
PubMed Abstract available

HUCHZERMEYER C, Stingl K, Kremers J
Multidimensional Functional Phenotyping Based on Photoreceptor-Directed Temporal Contrast Sensitivity Defects in Inherited Retinal Diseases.
Invest Ophthalmol Vis Sci. 2025;66:25.
PubMed Abstract available

KIM MS, Choi SH, Park HY, Jang SY, et al
Role of SerpinA3 in the Pathogenesis of Graves' Orbitopathy in Orbital Fibroblasts.
Invest Ophthalmol Vis Sci. 2025;66:20.
PubMed Abstract available

PAREKH Z, Xiao J, Mani A, Evans Q, et al
Fecal Microbial Profiles and Short-Chain Fatty Acid/Bile Acid Metabolomics in Patients With Age-Related Macular Degeneration: A Pilot Study.
Invest Ophthalmol Vis Sci. 2025;66:21.
PubMed Abstract available

GAO M, Guo Y, Hormel TT, Wang J, et al
Nonperfused Retinal Capillaries-A New Method Developed on OCT and OCTA.
Invest Ophthalmol Vis Sci. 2025;66:22.
PubMed Abstract available

HARTNESS EM, Shevalye H, Skeie JM, Eggleston T, et al
Iron-Sulfur Clusters and Iron Responsive Element Binding Proteins Mediate Iron Accumulation in Corneal Endothelial Cells in Fuchs Dystrophy.
Invest Ophthalmol Vis Sci. 2025;66:23.
PubMed Abstract available

YANG J, Li Y, Zhang Q, Zeng S, et al
Optic Nerve Morphology Influences Structure-Function Relationship in Early Glaucoma With and Without High Myopia.
Invest Ophthalmol Vis Sci. 2025;66:18.
PubMed Abstract available

ITO S, Oyama Y, Yuasa T, Amano K, et al
Heterozygous Tcf4 Deficiency Mitigates Fuchs Endothelial Corneal Dystrophy Progression in a Mouse Model.
Invest Ophthalmol Vis Sci. 2025;66:19.
PubMed Abstract available

TAKAHASHI T, Yokoi-Igarashi T, Takahashi H, Nakao N, et al
Evaluating the Volume of Eyes With Pathologic Myopia Using 3D MRI.
Invest Ophthalmol Vis Sci. 2025;66:13.
PubMed Abstract available

ZHU S, Zhang L, Tong P, Chen J, et al
Nicotinamide Riboside Mitigates Retinal Degeneration by Suppressing Damaged DNA-Stimulated Microglial Activation and STING-Mediated Pyroptosis.
Invest Ophthalmol Vis Sci. 2025;66:14.
PubMed Abstract available

LIN Y, Yang L, Li Y, Dou S, et al
CD4+CD25- T-Cell-Secreted IFN-gamma Promotes Corneal Nerve Degeneration in Diabetic Mice.
Invest Ophthalmol Vis Sci. 2025;66:15.
PubMed Abstract available

CHEN L, Yu Z, Zhu S, Song S, et al
Astrocyte-Derived Extracellular Vesicles Alleviate Optic Nerve Injury Through Remodeling of Retinal Microenvironmental Homeostasis.
Invest Ophthalmol Vis Sci. 2025;66:16.
PubMed Abstract available

LIU S, Du N, Ge K, Hu J, et al
NMN Supplementation Inhibits Endothelial Cell ROS-Mediated Src/Pi3k/Akt Signaling Pathway to Protect High-Altitude Blood-Retinal Barrier.
Invest Ophthalmol Vis Sci. 2025;66:51.
PubMed Abstract available

XIAO H, Hu L, Lin X, Liu L, et al
Pax6 Directly Regulates the Raver2/sFlt-1 Expression in Corneal Epithelial Cells to Maintain the Cornea's Avascular Privilege.
Invest Ophthalmol Vis Sci. 2025;66:52.
PubMed Abstract available

RUDRAPRASAD D, Nirmal J, Mishra DK, Joseph J, et al
RNA-Sequencing Reveals the Modulation of the NLRP3 Inflammasome by miR-223-3p in Extracellular Vesicles in Bacterial Endophthalmitis.
Invest Ophthalmol Vis Sci. 2025;66:53.
PubMed Abstract available

TORIBIO D, Morokuma J, Pellino D, Hardt M, et al
Quantitative Changes in the Proteome of Chronically Inflamed Lacrimal Glands From a Sjogren's Disease Animal Model.
Invest Ophthalmol Vis Sci. 2025;66:44.
PubMed Abstract available

CHEN X, Rong Y, Jiang Y, Zhang Q, et al
Vitamin K1 Alleviates Retinal Inflammation Following Acute Ocular Hypertension by Modulating Microglial Ferroptosis.
Invest Ophthalmol Vis Sci. 2025;66:46.
PubMed Abstract available

SONG WQ, Zhong WF, Li ZH, Liu D, et al
Biological Age Acceleration, Genetic Susceptibility, and Incident Glaucoma Risk.
Invest Ophthalmol Vis Sci. 2025;66:47.
PubMed Abstract available

ZHU X, Qi B, Ren Z, Cong L, et al
Targeted Neuroprotection of Retinal Ganglion Cells Via AAV2-hSyn-NGF Gene Therapy in Glaucoma Models.
Invest Ophthalmol Vis Sci. 2025;66:48.
PubMed Abstract available

SIM R, Riau AK, Shahinda Humaira Binte Halim N, Mehta JS, et al
Quantitative Stain-Free Conjunctival Collagen Imaging in Cicatrizing Conjunctivitis Using Second Harmonic Generation-Two Photon Excitation Technology.
Invest Ophthalmol Vis Sci. 2025;66:49.
PubMed Abstract available

KOYANAGI Y, Sajiki AF, Yuki K, Ushida H, et al
Application of Metagenomic Long-Read Sequencing for the Diagnosis of Herpetic Uveitis.
Invest Ophthalmol Vis Sci. 2025;66:50.
PubMed Abstract available

LI S, Xie J, Xiang J, Yan R, et al
Corneal Sensory Nerve Injury Disrupts Lacrimal Gland Function by Altering Circadian Rhythms in Mice.
Invest Ophthalmol Vis Sci. 2025;66:40.
PubMed Abstract available

LI J, Ji H, Xu Y, Zhang W, et al
TUT7-Mediated Uridine Degradation of MCPIP1 in the Pterygium to Regulate TRAF6-Mediated Autophagy.
Invest Ophthalmol Vis Sci. 2025;66:41.
PubMed Abstract available

DUOT M, Coomson SY, Shrestha SK, Nagulla MVMK, et al
Transcriptome Meta-Analysis Uncovers Cell-Specific Regulatory Relationships in Embryonic, Juvenile, Adult, and Aged Mouse Lens Epithelium and Fibers.
Invest Ophthalmol Vis Sci. 2025;66:42.
PubMed Abstract available

WANG B, Liang L, Zeng H, Yang X, et al
Single-Cell RNA Sequencing Revealed Functional Conjunctival Keratinocytes Loss via TGF-beta-Wnt/beta-Catenin Signaling in Sjogren's Syndrome Related Dry Eye.
Invest Ophthalmol Vis Sci. 2025;66:43.
PubMed Abstract available

SEKIRYU T, Sugano Y, Itagaki K, Honjo J, et al
Three-Dimensional Characteristics of Choroidal Vasculature Associated With Filling Delay in Central Serous Chorioretinopathy.
Invest Ophthalmol Vis Sci. 2025;66:33.
PubMed Abstract available

ZHUANG X, Gao F, Xuan Y, Sun Z, et al
Novel OCT Angiography Features, von Hippel-Lindau Disease Association, and Genetic Characterization of Juxtapapillary Retinal Capillary Hemangiomas.
Invest Ophthalmol Vis Sci. 2025;66:34.
PubMed Abstract available

LI X, Liu A, Zhou Y, Qi H, et al
Proliferator-Activated Receptor Alpha Inhibits Abnormal Extracellular Matrix Accumulation and Maintains Energy Metabolism in Late-Onset Fuchs Endothelial Corneal Dystrophy.
Invest Ophthalmol Vis Sci. 2025;66:36.
PubMed Abstract available

WEI X, Ma S, Zhou Y, Cui H, et al
A Novel AAV Capsid-Mediated RS1 Gene Therapy Restored Retinal Function to Wild-Type Levels in Rs1R213W Mouse Model.
Invest Ophthalmol Vis Sci. 2025;66:37.
PubMed Abstract available

GONG X, Boydstun IP, Lawhon WT, Hanna NN, et al
Clinical Spectrum and Molecular Characteristics of Inherited Ocular Diseases in a Cohort of Pediatric Patients With Infantile Nystagmus Syndrome.
Invest Ophthalmol Vis Sci. 2025;66:39.
PubMed Abstract available

WANG Y, Xu Z, Wei L, Lu Y, et al
KGF-2 Alleviates Dry Eye Disease by Regulating the HMGB1/TLR4 Pathway.
Invest Ophthalmol Vis Sci. 2025;66:28.
PubMed Abstract available

ZHANG P, Manna SK, Goswami M, Zawadzki RJ, et al
A Narrowband 635 nm Autofluorescence Peak in Albino Mouse Eyes Found With Multi-Modal Imaging Reveals the Presence of Protoporphyrin IX in the Choroid.
Invest Ophthalmol Vis Sci. 2025;66:29.
PubMed Abstract available

LI X, Wang S, Wang Y, Chen R, et al
Clinical and Molecular Landscape of GLRA2 in X-Linked Early-Onset High Myopia.
Invest Ophthalmol Vis Sci. 2025;66:30.
PubMed Abstract available

DEVI P, Bhengra CM, Kumar D, Deshmukh R, et al
Depth-Related Visuomotor Performance in Keratoconus and Its Relationship to Stereopsis.
Invest Ophthalmol Vis Sci. 2025;66:31.
PubMed Abstract available

HUANG K, Xia M, Gong Q, Li K, et al
The Relationship Between Binocular Imbalance and Myopic Shift in Unoperated Eyes After Unilateral SMILE and tPRK.
Invest Ophthalmol Vis Sci. 2025;66:32.
PubMed Abstract available

SHIMIZU T, Hayashi T, Kurita J, Yuda K, et al
Antigen Presentation by Extracellular Vesicles in the Acute Phase of Corneal Transplantation.
Invest Ophthalmol Vis Sci. 2025;66:38.
PubMed Abstract available

CHEN M, Li J, Jiang N, Zhou J, et al
Motion Misperception in Anisomyopia Before and After Optical Correction.
Invest Ophthalmol Vis Sci. 2025;66:71.
PubMed Abstract available

XIAO X, Zhao J, Lin S, Yang Y, et al
Relationships Between Retinal Vascular Characteristics and Systemic Indicators in Patients With Diabetes Mellitus.
Invest Ophthalmol Vis Sci. 2025;66:72.
PubMed Abstract available

ZHANG D, Qu J, Ke C, Kong X, et al
Macrophage-Hosted Porphyromonas gingivalis Is a Risk Factor for Cataract Development.
Invest Ophthalmol Vis Sci. 2025;66:68.
PubMed Abstract available

HA SK, Ding X, Romano F, Overbey KM, et al
Structure-Function Associations Between Quantitative Contrast Sensitivity Function And Peripapillary Optical Coherence Tomography Angiography in Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:69.
PubMed Abstract available

BIANCO L, Antropoli A, Benadji A, Atia R, et al
PCARE-Associated Retinopathy - Genetics, Clinical Characteristics, and Natural History.
Invest Ophthalmol Vis Sci. 2025;66:61.
PubMed Abstract available

BOLDU-ROIG J, Sorli-Clemente E, Kuljuh-Causevic A, Loras A, et al
Iris Pigmented Lesions: Unraveling the Genetic Basis of Iris Freckles and Nevi.
Invest Ophthalmol Vis Sci. 2025;66:62.
PubMed Abstract available

PENG Y, Zhang Y, Kam KW, Wong G, et al
Associations of Cardiovascular Health and New-Onset Age-Related Macular Diseases From UK Biobank.
Invest Ophthalmol Vis Sci. 2025;66:63.
PubMed Abstract available

LIN ZX, Zhang XJ, Tang FY, Zhang Y, et al
Association of Retinal Microvasculature With Myopia Progression in Children: The Hong Kong Children Eye Study.
Invest Ophthalmol Vis Sci. 2025;66:64.
PubMed Abstract available

FRANK-PUBLIG S, Bogunovic H, Birner K, Gumpinger M, et al
Quantifications of Outer Retinal Bands in Geographic Atrophy by Comparing Superior Axial Resolution and Conventional OCT.
Invest Ophthalmol Vis Sci. 2025;66:65.
PubMed Abstract available

ZHAO L, Li N, Shi X, Zhang J, et al
Enhanced Therapeutic Effect of IL-10-ADSCs on Rabbit Autoimmune Dacryoadenitis By Suppressing T Follicular Helper Cell Responses Via miR-142-5p/RC3H1 Axis.
Invest Ophthalmol Vis Sci. 2025;66:66.
PubMed Abstract available

WANG W, Ren R, Liu Y, Ye X, et al
Life's Essential 8, Genetic Susceptibility, and the Risk of Age-Related Macular Degeneration: A Prospective Cohort Study.
Invest Ophthalmol Vis Sci. 2025;66:54.
PubMed Abstract available

WANG M, Chen R, Wang Y, Li Y, et al
Expression Distribution of Keratins in Normal and Pathological Corneas and the Regulatory Role of Krt17 on Limbal Stem Cells.
Invest Ophthalmol Vis Sci. 2025;66:55.
PubMed Abstract available

GOERDT L, Clark ME, Thomas TN, Gao L, et al
Fluorescence Lifetime Imaging Ophthalmoscopy, Vision, and Chorioretinal Asymmetries in Aging and Age-Related Macular Degeneration: ALSTAR2.
Invest Ophthalmol Vis Sci. 2025;66:56.
PubMed Abstract available

ERMIS S, Ozal E, Simsek E, Tastan O, et al
Assessment of Ocular Magnification in Relation to Biometric Parameters and Measurement Techniques: A Prospective Study.
Invest Ophthalmol Vis Sci. 2025;66:57.
PubMed Abstract available

PAN SY, Weng CH, Tsai SF, Lin HJ, et al
Use of SGLT2 Inhibitors Versus DPP-4 Inhibitors and Age-Related Macular Degeneration in Patients WithType 2 Diabetes: A Multinational Cohort Study.
Invest Ophthalmol Vis Sci. 2025;66:58.
PubMed Abstract available

HUANG YH, Huang YS, Lin CY, Lai YJ, et al
The Exponential Constriction Model of the Ellipsoid Zone in Taiwanese Individuals With RPGR-Related X-Linked Retinitis Pigmentosa.
Invest Ophthalmol Vis Sci. 2025;66:59.
PubMed Abstract available

ROMO-AGUAS JC, de Guimaraes TAC, Kalitzeos A, Aychoua N, et al
Detailed Clinical, Ophthalmic, and Genetic Characterization of MYO7A-Associated Usher Syndrome.
Invest Ophthalmol Vis Sci. 2025;66:60.
PubMed Abstract available

ABE T, Daigaku R, Yuting X, Daigaku Y, et al
Retinal Pigment Epithelium Specific Metabolic Phenotypes Are Regulated by High-Mobility Group Protein N1.
Invest Ophthalmol Vis Sci. 2025;66:70.
PubMed Abstract available

LI YJ, Zhang ZY, Liu TY, Liu HY, et al
Retinal Structure and Microcirculation Alterations in Patients With Papillary Thyroid Carcinoma: An Optical Coherence Tomography and Angiography Study.
Invest Ophthalmol Vis Sci. 2025;66:73.
PubMed Abstract available

DOW E, Kearney S, Day M
Absolute Risks and Decision Tools for Communicating the Risks of Visual Impairment From Myopia-Related Diseases.
Invest Ophthalmol Vis Sci. 2025;66:82.
PubMed Abstract available

GIOVANNETTI F, Pontecorvi P, Megiorni F, Armentano M, et al
Conjunctival MicroRNA Expression Signature in Primary Sjogren's Syndrome Dry Eye: A NanoString-Based Bioinformatic Analysis.
Invest Ophthalmol Vis Sci. 2025;66:80.
PubMed Abstract available

WANG A, Li Z, Jiang Y, Chen M, et al
Prox1 Protein in Corneal Limbal Lymphatic Vessels Maintains Limbal Stem Cell Stemness and Regulates Corneal Injury Repair.
Invest Ophthalmol Vis Sci. 2025;66:81.
PubMed Abstract available

PAS JAAH, Li CHZ, Van den Broeck F, Dhooge PPA, et al
Progression of Atrophy as a Function of ABCA4 Variants and Age of Onset in Stargardt Disease.
Invest Ophthalmol Vis Sci. 2025;66:76.
PubMed Abstract available

CHEN B, Qiu J, Meng Y, Liang Y, et al
Radiomics Analysis Based on Optical Coherence Tomography to Prognose the Efficacy of Anti-VEGF Therapy of Retinal Vein Occlusion-Related Macular Edema.
Invest Ophthalmol Vis Sci. 2025;66:74.
PubMed Abstract available

FAHIM AT, Carroll J
Supporting Effective Peer Review at Investigative Ophthalmology & Visual Science.
Invest Ophthalmol Vis Sci. 2025;66:79.
PubMed

March 2025

LI J, Ma Y, Xie L, Zhuo K, et al
Comprehensive Proteomic Profiling of Exfoliation Glaucoma Via Mass Spectrometry Reveals SVEP1 as a Potential Biomarker.
Invest Ophthalmol Vis Sci. 2025;66:19.
PubMed Abstract available

JIANG D, Yu J, Wu X, Yu X, et al
Isolated Mitochondrial Transplantation as a Novel Treatment for Corneal Chemical Burns.
Invest Ophthalmol Vis Sci. 2025;66:14.
PubMed Abstract available

LEE A, Law DTW, Kan AHS, Cruz FFP, et al
The Epidemiology of Eye Cancer, Eyelid Cancer, and Ophthalmic Lymphoma in a Chinese Population in Hong Kong: A Population-Based Registry Study 2005-2018.
Invest Ophthalmol Vis Sci. 2025;66:15.
PubMed Abstract available

NAKAGAWA T, Honda T, Yuasa T, Nishiuchi G, et al
The TCF4 Gene Regulates Apoptosis of Corneal Endothelial Cells in Fuchs Endothelial Corneal Dystrophy.
Invest Ophthalmol Vis Sci. 2025;66:16.
PubMed Abstract available

GUO X, Gao M, Qi Y, Shi Q, et al
Magnetic Resonance Dacryocystography for Precise Diagnosis of Lacrimal and Perilacrimal Lesions.
Invest Ophthalmol Vis Sci. 2025;66:17.
PubMed Abstract available

SHAW EM, Anderson DM, Periasamy R, Schey KL, et al
Porcine Sub-Retinal Pigment Epithelium Deposits: A Model for Dry Age-Related Macular Degeneration With Comparison to Human Drusen.
Invest Ophthalmol Vis Sci. 2025;66:18.
PubMed Abstract available

LIU D, Meng Z, Jin C, Chen F, et al
Fibronectin Mediates Endothelial-to-Mesenchymal Transition in Retina Angiogenesis.
Invest Ophthalmol Vis Sci. 2025;66:10.
PubMed Abstract available

HYSI PG, Hammond CJ
An Ocular Gene-Set Expression Library for Heritability Partition and Cell Line Enrichment Analyses.
Invest Ophthalmol Vis Sci. 2025;66:11.
PubMed Abstract available

LOU J, Huang H, Peng Y, Wang C, et al
One-Month-Old Rabbits Exhibit a Longer Postoperative Remodeling in Extraocular Muscles Compared to 3-Month-Old Rabbits.
Invest Ophthalmol Vis Sci. 2025;66:12.
PubMed Abstract available

LI Z, Liu X, Li Z, Xiao Z, et al
STING Deficiency Promotes Th17-Like Tfh to Aggravate the Experimental Autoimmune Uveitis.
Invest Ophthalmol Vis Sci. 2025;66:8.
PubMed Abstract available

LU ZJ, Ye JG, Li JN, Liang JB, et al
Single-Cell Multiomics Analysis of Early Wound Response Programs in the Mouse Corneal Epithelium.
Invest Ophthalmol Vis Sci. 2025;66:9.
PubMed Abstract available

CAO M, Zhang Y, Li Y, Zhang X, et al
Ameboid Microglia as a Scavenger Role in Phagocytosis of Photoreceptor Outer Segment in an Experimental Retinal Detachment Model.
Invest Ophthalmol Vis Sci. 2025;66:4.
PubMed Abstract available

OUYANG P, Qi J, Tong B, Li Y, et al
Butyrate Ameliorates Graves' Orbitopathy Through Regulating Orbital Fibroblast Phenotypes and Gut Microbiota.
Invest Ophthalmol Vis Sci. 2025;66:5.
PubMed Abstract available

LARBI D, Rief AM, Kang S, Chen S, et al
Dicer Loss in Muller Glia Leads to a Defined Sequence of Pathological Events Beginning With Cone Dysfunction.
Invest Ophthalmol Vis Sci. 2025;66:7.
PubMed Abstract available

WAXMAN S, Schilpp H, Linton A, Jakobs TC, et al
Morphological Comparison of Astrocytes in the Lamina Cribrosa and Glial Lamina.
Invest Ophthalmol Vis Sci. 2025;66:1.
PubMed Abstract available

ZHANG M, Liang Y, Wu H, Zong R, et al
Ocular Surface Involvements in the Development of Sjogren's Syndrome-Associated Dry Eye in the IL14alpha Transgenic Mouse.
Invest Ophthalmol Vis Sci. 2025;66:2.
PubMed Abstract available

O'NEIL A, Welikala RA, Barman S, Owen CG, et al
Factors Associated With Retinal Vessel Traits in the Canadian Longitudinal Study on Aging.
Invest Ophthalmol Vis Sci. 2025;66:13.
PubMed Abstract available

BARRETO P, Farinha C, Coimbra R, Silva R, et al
Author Response: Unveiling Statins and Genetics in Age-Related Macular Degeneration Progression: What Is the Appropriate Modeling Strategy?
Invest Ophthalmol Vis Sci. 2025;66:3.
PubMed

WANG T, Chen X, Li M, Bi H, et al
A Novel Model for Cornea Power Shift in Eyes Wearing Orthokeratology Lenses With Different Back Optic Zone Diameters for Myopia Control.
Invest Ophthalmol Vis Sci. 2025;66:29.
PubMed Abstract available

BIRNER K, Reiter GS, Steiner I, Zarghami A, et al
Structure-Function Correlation of Deep-Learning Quantified Ellipsoid Zone and Retinal Pigment Epithelium Loss and Microperimetry in Geographic Atrophy.
Invest Ophthalmol Vis Sci. 2025;66:26.
PubMed Abstract available

TANG H, Lin Y, Hu J
Long Non-Coding RNA Osr2 Promotes Fusarium solani Keratitis Inflammation via the miR-30a-3p/ Xcr1 Axis.
Invest Ophthalmol Vis Sci. 2025;66:27.
PubMed Abstract available

LIU F, Wang Y, Niu L, Zhao J, et al
Characteristics of Retina, Choroid, and Retrobulbar Blood Flow in Myopes With Posterior Staphyloma Using Ultra-Widefield OCTA and CDI.
Invest Ophthalmol Vis Sci. 2025;66:21.
PubMed Abstract available

HORMEL TT, Beaulieu WT, Wang J, Sun JK, et al
Artificial Intelligence Versus Rules-Based Approach for Segmenting NonPerfusion Area in a DRCR Retina Network Optical Coherence Tomography Angiography Dataset.
Invest Ophthalmol Vis Sci. 2025;66:22.
PubMed Abstract available

HUO QY, Zhang RZ, Jia WN, Wang YL, et al
Corneal Biomechanics Are Associated With FBN1 Mutations in Patients With Marfan Syndrome and Ectopia Lentis.
Invest Ophthalmol Vis Sci. 2025;66:23.
PubMed Abstract available

DIAZ D, Sassani JW, Zagon IS, McLaughlin PJ, et al
Reversal of Diabetic Dry Eye by Topical Opioid Receptor Blockade Follows Dual Pathways.
Invest Ophthalmol Vis Sci. 2025;66:24.
PubMed Abstract available

POOLE K, Iyer KS, Schmidtke DW, Petroll WM, et al
Corneal Keratocytes, Fibroblasts, and Myofibroblasts Exhibit Distinct Transcriptional Profiles In Vitro.
Invest Ophthalmol Vis Sci. 2025;66:28.
PubMed Abstract available

HANNA J, Touahri Y, Pak A, David LA, et al
Pten Loss Triggers Progressive Photoreceptor Degeneration in an mTORC1-Independent Manner.
Invest Ophthalmol Vis Sci. 2025;66:45.
PubMed Abstract available

SHI M, Zhou R, Shen W, Liang Y, et al
LncRNA ENST00000581911 Regulates Extraocular Muscle Remodeling by Interacting With KHSRP in Thyroid Eye Disease.
Invest Ophthalmol Vis Sci. 2025;66:46.
PubMed Abstract available

SZCZEPAN M, Llorian-Salvador M, Yi C, Hughes D, et al
Differential Roles of Macrophages and Microglia in Subretinal Fibrosis Secondary to Neovascular Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2025;66:41.
PubMed Abstract available

MIAO A, Yang F, Chen T, Qian D, et al
Lens Thickness-to-Anterior Chamber Depth Ratio: A Biometric Determinant of Chamber Angle Width in Han Chinese Cataract Patients.
Invest Ophthalmol Vis Sci. 2025;66:42.
PubMed Abstract available

SHI WQ, Li B, Shao Y, Han W, et al
EFEMP1-Mediated Regulation of Choroidal Vascular Dysfunction in Myopia: Insights Into the FOXO3/VEGFA Pathway as a Therapeutic Target.
Invest Ophthalmol Vis Sci. 2025;66:43.
PubMed Abstract available

LI B, Liu J, Zhang D, Chu Y, et al
Evodiamine Promotes Autophagy and Alleviates Oxidative Stress in Dry Eye Disease Through the p53/mTOR Pathway.
Invest Ophthalmol Vis Sci. 2025;66:44.
PubMed Abstract available

SUGAWARA R, Usui Y, Saito A, Nezu N, et al
An Approach to Predict Intraocular Diseases by Machine Learning Based on Vitreous Humor Immune Mediator Profile.
Invest Ophthalmol Vis Sci. 2025;66:38.
PubMed Abstract available

ZHOU X, Xu X, Wang Q, Lai Y, et al
Targeted siRNA Delivery Against RUNX1 Via tFNA: Inhibiting Retinal Neovascularization and Restoring Vessels Through Dll4/Notch1 Signaling.
Invest Ophthalmol Vis Sci. 2025;66:39.
PubMed Abstract available

LI Y, Tang J, Jing G, Li Y, et al
Orbital Clinicopathological Differences in Thyroid Eye Disease: An Analysis of Cytokines With Histopathological and Clinical Correlation.
Invest Ophthalmol Vis Sci. 2025;66:33.
PubMed Abstract available

ZHANG J, Jin L, Chen Q, Wang D, et al
Changes in Lens Thickness and Power Before and After Myopia Onset.
Invest Ophthalmol Vis Sci. 2025;66:36.
PubMed Abstract available

TALWAR S, Mazade R, Bentley-Ford M, Yu J, et al
Modulation of All-Trans Retinoic Acid by Light and Dopamine in the Murine Eye.
Invest Ophthalmol Vis Sci. 2025;66:37.
PubMed Abstract available

SUEMATSU N, Sato AY, Kimura A, Shimegi S, et al
Perceptual Visual Acuity Declines With Age in a Rat Model of Retinitis Pigmentosa While Light Perception is Maintained.
Invest Ophthalmol Vis Sci. 2025;66:31.
PubMed Abstract available

MAGAGNOLI J, Cummings T, Hardin JW, Sutton SS, et al
NLRP3 Activation With Bisphosphonate Use and the Risk of Incident Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2025;66:32.
PubMed Abstract available

KAUR S, Sohnen P, Kumar S, Vohra M, et al
The Secreted Ly6/uPAR-Related Protein-1 (SLURP1) Protects the Cornea From Oxidative Stress.
Invest Ophthalmol Vis Sci. 2025;66:30.
PubMed Abstract available

MARMALIDOU A, Siddiqui H, Jamil MU, Woo KM, et al
Comparison Between MAIA and MP-3 In Healthy Subjects and Patients With Diabetes, Diabetic Retinopathy, and Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2025;66:59.
PubMed Abstract available

XU K, Xu Y, Qin Y, Zhang Y, et al
The Effect of Partial Sleep Deprivation on Retinal Microvasculature in Myopia With Different Axial Lengths.
Invest Ophthalmol Vis Sci. 2025;66:57.
PubMed Abstract available

ANTONY M, Maldoddi R, Atchison DA, Verkicharla PK, et al
Diversity of Peripheral Refraction Patterns-Have These Been Oversimplified?
Invest Ophthalmol Vis Sci. 2025;66:58.
PubMed Abstract available

GURUNG RL, Nangia C, Cai T, FitzGerald LM, et al
Genome-Wide Association Study to Identify Genetic Variants Associated With Diabetic Maculopathy.
Invest Ophthalmol Vis Sci. 2025;66:55.
PubMed Abstract available

LARA-LOPEZ A, Gonzalez-Imaz K, Rodriguez-Hidalgo M, Sarasola-Gastesi M, et al
Topical Administration of Novel FKBP12 Ligand MP-004 Improves Retinal Function and Structure in Retinitis Pigmentosa Models.
Invest Ophthalmol Vis Sci. 2025;66:56.
PubMed Abstract available

SADEGHI E, Du K, Ajayi O, Davis E, et al
Three-Dimensional Choroidal Vessels Assessment in Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:50.
PubMed Abstract available

SOLTYSOVA A, Dvorska D, Ficek A, Pecimonova M, et al
Clinical Value of MLPA for Prognostic Assessment of Chromosomal Rearrangements and DNA Methylation in Uveal Melanoma.
Invest Ophthalmol Vis Sci. 2025;66:51.
PubMed Abstract available

ALBERTOS-ARRANZ H, Martinez-Gil N, Sanchez-Saez X, Molina-Martin JC, et al
Neuronal Degeneration and Glial Activation in the Absence of Vascular Changes in Human Retinas of Patients With Diabetes.
Invest Ophthalmol Vis Sci. 2025;66:53.
PubMed Abstract available

ZHANG H, Lan S, Ren D, Chen X, et al
Epigenetic ALYREF/UHRF1/RHOB Axis in Corneal Wound Healing and Implications for Epithelial Tumorigenesis.
Invest Ophthalmol Vis Sci. 2025;66:54.
PubMed Abstract available

YANG YF, Holden P, Sun YY, Faralli JA, et al
Fibrosis-Related Gene and Protein Expression in Normal and Glaucomatous Trabecular Meshwork Cells.
Invest Ophthalmol Vis Sci. 2025;66:48.
PubMed Abstract available

SCHOOT UITERKAMP FE, Maes ME, Alamalhoda MA, Firoozi A, et al
Optic Nerve Crush Does Not Induce Retinal Ganglion Cell Loss in the Contralateral Eye.
Invest Ophthalmol Vis Sci. 2025;66:49.
PubMed Abstract available

GOERDT L, Berlin A, Gao L, Swain TA, et al
Topographic Analysis of Two-Wavelength Autofluorescence Supports Higher Macular Xanthophyll Pigment in AMD Than Aging: ALSTAR2 Baseline.
Invest Ophthalmol Vis Sci. 2025;66:61.
PubMed Abstract available

JURGENS JA, Matos Ruiz PM, King J, Foster EE, et al
Gene Identification for Ocular Congenital Cranial Motor Neuron Disorders Using Human Sequencing, Zebrafish Screening, and Protein Binding Microarrays.
Invest Ophthalmol Vis Sci. 2025;66:62.
PubMed Abstract available

February 2025

LIAO Q, Yang J, Shi H, Mengjiang R, et al
Aurora A Kinase Inhibition Is Synthetic Lethal With the Activation of MYCN in Retinoblastoma.
Invest Ophthalmol Vis Sci. 2025;66:20.
PubMed Abstract available

NAIK P, McLeod DS, Bhutto IA, Edwards MM, et al
Regional Alterations in Muller Cell Protein Expression in Human and a Rat Model of Geographic Atrophy.
Invest Ophthalmol Vis Sci. 2025;66:21.
PubMed Abstract available

LIU X, Yuan Y, Wu Y, Zhu C, et al
Extracellular Matrix Stiffness Modulates Myopia Scleral Remodeling Through Integrin/F-Actin/YAP Axis.
Invest Ophthalmol Vis Sci. 2025;66:22.
PubMed Abstract available

VAN DER ENDE S, Bedard K, Wallace K, Mackley MP, et al
Gene Variant Spectrum in Probands With Familial Exudative Vitreoretinopathy Using an Expanded Panel.
Invest Ophthalmol Vis Sci. 2025;66:23.
PubMed Abstract available

BOL KF, Sweep MWD, Crowther MD, Gorris MAJ, et al
Transvitreal Retinochoroidal Biopsies of Primary Uveal Melanoma Reveal an Association of Low HLA Class I and High NK Cell Abundance in Low-Risk Disease.
Invest Ophthalmol Vis Sci. 2025;66:24.
PubMed Abstract available

GUPTA P, Vu TA, Wong CMJ, Thakur S, et al
Single and Multiple Visual Function Impairments and Associated- Vision-Related Quality of Life Impact in Older Adults Aged 60 to 100 Years.
Invest Ophthalmol Vis Sci. 2025;66:18.
PubMed Abstract available

ZHOU L, Fan S, Lu H, Zhang W, et al
Retinal and Choriocapillaris Thickness Changes in Spontaneously Diabetic Macaques.
Invest Ophthalmol Vis Sci. 2025;66:11.
PubMed Abstract available

BRANHAM K, Samarakoon L, Audo I, Ayala AR, et al
Characterizing the Genetic Basis for Inherited Retinal Disease: Lessons Learned From the Foundation Fighting Blindness Clinical Consortium's Gene Poll.
Invest Ophthalmol Vis Sci. 2025;66:12.
PubMed Abstract available

HAN F, Wang L, Wu J, Shen L, et al
Inhibition of LRRK2 Ameliorates Aspergillus fumigatus Keratitis by Regulating STING Signaling Pathways.
Invest Ophthalmol Vis Sci. 2025;66:13.
PubMed Abstract available

LI Y, Luo Z, Liu Z, Zhu X, et al
IL-23 Promotes gammadeltaT Cell Activity in Dry Eye Disease Progression.
Invest Ophthalmol Vis Sci. 2025;66:10.
PubMed Abstract available

HU X, Feng J, Pan C, Sun Z, et al
HMGB1 Promotes Lysosome-Dependent Cell Death Induced Via Dry Eye by Disrupting Lysosomal Homeostasis.
Invest Ophthalmol Vis Sci. 2025;66:5.
PubMed Abstract available

FUTTERKNECHT S, Anders P, Mai J, Riedl S, et al
Targeted Microperimetry Grids for Focal Lesions in Intermediate AMD: PINNACLE Study Report 7.
Invest Ophthalmol Vis Sci. 2025;66:6.
PubMed Abstract available

CHANG MC, Lin DP, Chang HH
Hepatic Satellite Cell Activation and Alteration of Vitamin A Status Are Relevant to the Aggravation of Retinopathy by T2DM.
Invest Ophthalmol Vis Sci. 2025;66:7.
PubMed Abstract available

JONAS JB, Panda-Jonas S, Mehta JS, Jonas RA, et al
Anatomic Relationship Among Descemet's Membrane, Trabecular Meshwork, Scleral Spur, and Ciliary Muscle.
Invest Ophthalmol Vis Sci. 2025;66:8.
PubMed Abstract available

YAYLACIOGLU TUNCAY F, Reeves MJ, Yousaf S, Ullah E, et al
Genotype-Phenotype Spectrum of eyeGENE Patients With Familial Exudative Vitreoretinopathy: Novel Variants in Norrin/beta-Catenin Signaling Pathway Genes.
Invest Ophthalmol Vis Sci. 2025;66:9.
PubMed Abstract available

WU G, Notomi S, Xu Z, Fukuda Y, et al
Lamp2 Deficiency Enhances Susceptibility to Oxidative Stress-Induced RPE Degeneration.
Invest Ophthalmol Vis Sci. 2025;66:2.
PubMed Abstract available

JIANG Z, Zhang B, Jia S, Yuan X, et al
Molecular Subtype Identification and Potential Drug Prediction Based on Anoikis-Related Genes Expression in Keratoconus.
Invest Ophthalmol Vis Sci. 2025;66:3.
PubMed Abstract available

NAVIA JC, Alfonso A, Miller D, Maestre-Mesa J, et al
Prevalence of HSV Genomic Signatures Among Acanthamoeba Hosts and Contaminated Lens Cases: A Molecular and Clinical Study.
Invest Ophthalmol Vis Sci. 2025;66:4.
PubMed Abstract available

CHI H, Ma L, Zeng F, Wang X, et al
Senolytic Treatment Alleviates Corneal Allograft Rejection Through Upregulation of Angiotensin-Converting Enzyme 2 (ACE2).
Invest Ophthalmol Vis Sci. 2025;66:15.
PubMed Abstract available

CARROLL J
Behind the Scenes at Investigative Ophthalmology & Visual Science.
Invest Ophthalmol Vis Sci. 2025;66:19.
PubMed

KINDER L, Lindner M
Expression of Osteopontin in M2 and M4 Intrinsically Photosensitive Retinal Ganglion Cells in the Mouse Retina.
Invest Ophthalmol Vis Sci. 2025;66:14.
PubMed Abstract available

LIU J, Kang M, Wei Y, Zhang Z, et al
kexB Gene Correlates With Aspergillus flavus Keratitis Severity: A Whole-Genome Analysis.
Invest Ophthalmol Vis Sci. 2025;66:42.
PubMed Abstract available

RATEAUX M, Hadj-Rabia S, Barrois R, Zambrowski O, et al
Chiasmal Decussation in Oculo-Cutaneous Albinism Type 8.
Invest Ophthalmol Vis Sci. 2025;66:44.
PubMed Abstract available

ZHOU X, Cao J, Xie J, Tong W, et al
Effect of Dync1h1 on Phototransduction Protein Transport and the Development and Maintenance of Photoreceptor Cells in Zebrafish.
Invest Ophthalmol Vis Sci. 2025;66:38.
PubMed Abstract available

STOLOWY N, Gutmann L, Lupke M, David T, et al
OCT-Based Retina Assessment Reflects Visual Impairment in Multiple Sclerosis.
Invest Ophthalmol Vis Sci. 2025;66:39.
PubMed Abstract available

DING X, Zhou X, Liu X, Lai Y, et al
Targeting Runx1 in Pathological Retinal Angiogenesis: A Potential Therapeutic Approach.
Invest Ophthalmol Vis Sci. 2025;66:40.
PubMed Abstract available

GOTFREDSEN K, Abou-Taha A, Liisborg C, Krogh Nielsen M, et al
High Levels of C5a Are Associated With Reduced Macular Sensitivity in Patients With Myeloproliferative Neoplasms.
Invest Ophthalmol Vis Sci. 2025;66:41.
PubMed Abstract available

DU Q, Zhang Y, Huang Y
Peripheral Refraction and Axial Growth Rate After Multifocal or Monofocal Intraocular Lens Implantation in Chinese Pediatric Cataract Patients.
Invest Ophthalmol Vis Sci. 2025;66:33.
PubMed Abstract available

SCAVUZZI BM, Shanmugam S, Yang M, Yao J, et al
Remote Preconditioning Provides Protection Against Retinal Cell Death From Retinal Detachment.
Invest Ophthalmol Vis Sci. 2025;66:34.
PubMed Abstract available

KHAN MA, Fatima G, Emmanuel A, Kim SS, et al
Modeling Neuropathic Corneal Pain: Pulled Nerve Approach With Elevated Krt16 Gene Expression.
Invest Ophthalmol Vis Sci. 2025;66:35.
PubMed Abstract available

CHEN Y, Zhang X, Zhang Y, Zhang S, et al
Metabolomic Characteristics of Aqueous Humor in Wet Age-Related Macular Degeneration and the Impact of Anti-VEGF Treatment.
Invest Ophthalmol Vis Sci. 2025;66:37.
PubMed Abstract available

CHEN YY, Yang CM, Yang CH, Ho TC, et al
Elevated Very-Long-Chain Ceramides in the Vitreous Humor of Patients With Proliferative Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:28.
PubMed Abstract available

SHABANI H, De Ridder J, Asaad MA, Bramer WM, et al
Climate Determinants of Keratoconus: Insights From a Systematic Review of Prevalence.
Invest Ophthalmol Vis Sci. 2025;66:30.
PubMed Abstract available

KUMAR NG, Grosser MR, Wan S, Schator D, et al
Contact Lens Wear Alters Transcriptional Responses to Pseudomonas aeruginosa in Both the Corneal Epithelium and the Bacteria.
Invest Ophthalmol Vis Sci. 2025;66:31.
PubMed Abstract available

TANG Z, Yang D, Nguyen TX, Zhang S, et al
Relationship of OCT-Based Diabetic Retinal Neurodegeneration to the Development and Progression of Diabetic Retinopathy: A Cohort Study.
Invest Ophthalmol Vis Sci. 2025;66:32.
PubMed Abstract available

WANG Y, Rao T, Zhou J, You D, et al
Comprehensive Visualization of Choroidal Alterations in Thyroid Eye Disease With Ultra-Widefield OCT Angiography.
Invest Ophthalmol Vis Sci. 2025;66:25.
PubMed Abstract available

YUE Y, Patel SP, Nie J, Andrews CA, et al
Anthropometric Measures and Fuchs' Endothelial Corneal Dystrophy: The Women's Health Initiative Observational Study.
Invest Ophthalmol Vis Sci. 2025;66:26.
PubMed Abstract available

WANG X, Hoshi S, Liu R, Corradetti G, et al
Photoreceptor Function and Structure in Retinal Areas With Intraretinal Hyperreflective Foci in Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2025;66:27.
PubMed Abstract available

HE Y, Heumann P, Weilin Song M, Kadomoto S, et al
Changes in Optical Coherence Tomography Angiography Precede Clinical Onset of Placental Insufficiency.
Invest Ophthalmol Vis Sci. 2025;66:36.
PubMed Abstract available

ZHU F, Feng J, Pan Y, Ouyang L, et al
Mettl3-Mediated N6-Methyladenosine Modification Mitigates Ganglion Cell Loss and Retinal Dysfunction in Retinal Ischemia-Reperfusion Injury by Inhibiting FoxO1-Mediated Autophagy.
Invest Ophthalmol Vis Sci. 2025;66:58.
PubMed Abstract available

MOEKOTTE L, de Boer JH, Hiddingh S, de Ligt A, et al
Elevated Plasma Complement Factors in CRB1-Associated Inherited Retinal Dystrophies.
Invest Ophthalmol Vis Sci. 2025;66:55.
PubMed Abstract available

ZHU J, Ding D, Sun T, Zhang Y, et al
Oridonin Preserves Retinal Pigmented Epithelial Cell Tight Junctions and Ameliorates Choroidal Neovascularization.
Invest Ophthalmol Vis Sci. 2025;66:56.
PubMed Abstract available

KIM J, Kang JH, Wiggs JL, Zhao H, et al
Does Age Modify the Relation Between Genetic Predisposition to Glaucoma and Various Glaucoma Traits in the UK Biobank?
Invest Ophthalmol Vis Sci. 2025;66:57.
PubMed Abstract available

WANG C, Li YZ, Guo H, Zhou SR, et al
Melatonin Alleviates Age-Related Lacrimal Gland Dysfunction Via SIRT-1/NLRP3 Pathway.
Invest Ophthalmol Vis Sci. 2025;66:51.
PubMed Abstract available

ALIFF HL, Crockett AB, Chrenek MA, Nickerson JM, et al
Accessible LED Lightbox for Light-induced Retinal Damage in Pigmented Mice.
Invest Ophthalmol Vis Sci. 2025;66:49.
PubMed Abstract available

ALLON G, Lin S, Robson AG, Arno G, et al
Clinical, Genetic, Imaging and Electrophysiological Findings in a Cohort of Patients With GUCA1A-Associated Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:50.
PubMed Abstract available

YU J, Zhang Y, Kam KW, Ho M, et al
Lung Function as a Biomarker for Glaucoma: The UK Biobank Study.
Invest Ophthalmol Vis Sci. 2025;66:48.
PubMed Abstract available

Erratum in: Characterizing the Genetic Basis for Inherited Retinal Disease: Lessons Learned From the Foundation Fighting Blindness Clinical Consortium's Gene Poll.
Invest Ophthalmol Vis Sci. 2025;66:54.
PubMed

OKAWA H, Sampath AP
Temporal Transformation of the Rod Single-Photon Response in the Retinal Circuitry.
Invest Ophthalmol Vis Sci. 2025;66:52.
PubMed Abstract available

MA Q, Riau AK, Young RD, Bell JS, et al
Ultrastructural Aspects of Corneal Functional Recovery in Rats Following Intrastromal Keratocyte Injection.
Invest Ophthalmol Vis Sci. 2025;66:45.
PubMed Abstract available

FANG R, Zhang P, Kim D, Kweon J, et al
Robotic Visible-Light Optical Coherence Tomography Visualizes Segmental Schlemm's Canal Anatomy and Segmental Pilocarpine Response.
Invest Ophthalmol Vis Sci. 2025;66:47.
PubMed Abstract available

KOGO T, Muraoka Y, Hata M, Ishikura M, et al
Preferential Locations of Polypoidal Lesions and Adjacent Pigment Epithelium Detachments in Polypoidal Choroidal Vasculopathy in a Japanese Population.
Invest Ophthalmol Vis Sci. 2025;66:70.
PubMed Abstract available

BOURDIN A, Ranque B, Flamarion E, Charlier J, et al
Correlations Between Visual Field Defects and Macular Thinning in Sickle Cell Disease.
Invest Ophthalmol Vis Sci. 2025;66:67.
PubMed Abstract available

ZHOU H, Hu Y, Qin G, Kong J, et al
The Signature of Serum Modified Nucleosides in Uveitis.
Invest Ophthalmol Vis Sci. 2025;66:68.
PubMed Abstract available

KAIDO M, Arita R, Mitsukura Y, Sumali B, et al
Disruption in Autonomic Nervous Activity Is Associated With Central and Peripheral-Level in Dry Eye With Unstable Tear Film.
Invest Ophthalmol Vis Sci. 2025;66:69.
PubMed Abstract available

LI H, Harvey DH, Dai J, Swingle SP, et al
Characterization, Enrichment, and Computational Modeling of Cross-Linked Actin Networks in Transformed Trabecular Meshwork Cells.
Invest Ophthalmol Vis Sci. 2025;66:65.
PubMed Abstract available

WAGNER S, Settele A, Strasser T
Retinal Responses to Short- and Longer-Term Predominant ON or OFF Stimulation in Emmetropes and Myopes.
Invest Ophthalmol Vis Sci. 2025;66:66.
PubMed Abstract available

SHAH R, Amador C, Poe AJ, Spektor TM, et al
Identification of Wnt-5a Receptors Important in Diabetic and Non-Diabetic Corneal Epithelial Wound Healing.
Invest Ophthalmol Vis Sci. 2025;66:64.
PubMed Abstract available

KANNAN R, Shetty R, Panigrahi T, Koh SK, et al
Untargeted Tear Proteomics in a Large South-Asian Cohort Reveals Inflammatory Signaling, ECM Remodeling, and Altered Metabolism in Keratoconus.
Invest Ophthalmol Vis Sci. 2025;66:60.
PubMed Abstract available

SHARMA P, Naqvi RA, Borase H, Kapoor D, et al
Global MicroRNA Profiling of HSV-1 Infected Cornea Identifies miR-329 as a Novel Regulator of Virus Infection.
Invest Ophthalmol Vis Sci. 2025;66:61.
PubMed Abstract available

CHUNG STL, Legge GE
Is the Normal Periphery in Young Adults a Good Model for Reading in the Presence of Central Vision Loss?
Invest Ophthalmol Vis Sci. 2025;66:62.
PubMed Abstract available

SAITO M, Mitamura M, Fukutsu K, Zhenyu D, et al
Retinal Arteriovenous Information Improves the Prediction Accuracy of Deep Learning-Based baPWV Index From Color Fundus Photographs.
Invest Ophthalmol Vis Sci. 2025;66:63.
PubMed Abstract available

January 2025

QIU AW, Wang NY, Yin WJ, Zhu ZQ, et al
Retinal Muller Cell-Released Exosomal MiR-92a-3p Delivers Interleukin-17A Signal by Targeting Notch-1 to Promote Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:1.
PubMed Abstract available

CHEN Y, Xiong R, Zhang J, Yang S, et al
Ten-Year Change in Visual Function and Incidence of Visual Impairment in Highly Myopic Children and Adults.
Invest Ophthalmol Vis Sci. 2025;66:2.
PubMed Abstract available

WU R, Manny RE, Holmes JM, Melia BM, et al
Validating Rules for Defining No Improvement of Visual Acuity in Childhood Amblyopia.
Invest Ophthalmol Vis Sci. 2025;66:4.
PubMed Abstract available

PINEDO-DIAZ G, Lorenz B, Kunzel SH, Thiele S, et al
Deep Learning-Based SD-OCT Layer Segmentation Quantifies Outer Retina Changes in Patients With Biallelic RPE65 Mutations Undergoing Gene Therapy.
Invest Ophthalmol Vis Sci. 2025;66:5.
PubMed Abstract available

HE X, Fu Y, Xu Y, Ma L, et al
A Penetrable AAV2 Capsid Variant for Efficient Intravitreal Gene Delivery to the Retina.
Invest Ophthalmol Vis Sci. 2025;66:6.
PubMed Abstract available

PAN D, Hu G, Li J, Wang Z, et al
Blue Light Damages Retinal Ganglion Cells Via Endoplasmic Reticulum Stress and Autophagy in Chickens.
Invest Ophthalmol Vis Sci. 2025;66:3.
PubMed Abstract available

SINHA NR, Hofmann AC, Suleiman LA, Jeffrey MT, et al
Mustard Gas Induced Corneal Injury Involves Ferroptosis and p38 MAPK Signaling.
Invest Ophthalmol Vis Sci. 2025;66:23.
PubMed Abstract available

WANG L, Tian Y, Zhang H, Dong Y, et al
Caspase 3/GSDME-Mediated Corneal Epithelial Pyroptosis Promotes Dry Eye Disease.
Invest Ophthalmol Vis Sci. 2025;66:24.
PubMed Abstract available

DE GUIMARAES TAC, de Guimaraes IMC, Muthiah MN, Kalitzeos A, et al
Retinal Sensitivity in KCNV2-Associated Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:26.
PubMed Abstract available

NASTARANPOUR M, Suiwal S, Stachon T, Fries FN, et al
miRNA Expression Profile in Primary Limbal Epithelial Cells of Aniridia Patients.
Invest Ophthalmol Vis Sci. 2025;66:20.
PubMed Abstract available

CHANG CH, Peng IC, Huang YH
Recombinant Thrombomodulin Domain 1 Modulates Macrophage Polarization and Enhances Healing in Corneal Alkali Burns.
Invest Ophthalmol Vis Sci. 2025;66:21.
PubMed Abstract available

HUANG Y, He C, Hu Q, Liu Z, et al
Metabolic Atlas of Human Eyelid Infiltrative Basal Cell Carcinoma.
Invest Ophthalmol Vis Sci. 2025;66:11.
PubMed Abstract available

MERZBACH S, Schumacher-Klinger A, Klazas M, Hoffman A, et al
Anti-Inflammatory Effects of Clarstatin, a Shared-Epitope-Antagonistic Cyclic Peptide, on Experimental Autoimmune Uveitis in Mice.
Invest Ophthalmol Vis Sci. 2025;66:13.
PubMed Abstract available

ZHOU Y, Yu W, Ye Q, Xu Z, et al
Fixation Stability Deficits in Anisometropic Amblyopia.
Invest Ophthalmol Vis Sci. 2025;66:14.
PubMed Abstract available

BEHNKE V, Wolf A, Hector M, Langmann T, et al
C3aR1-Deletion Delays Retinal Degeneration in a White-Light Damage Mouse Model.
Invest Ophthalmol Vis Sci. 2025;66:15.
PubMed Abstract available

WANG L, Zou G, Yan Y, Shi R, et al
Idebenone Protects Photoreceptors Impaired by Oxidative Phosphorylation Disorder in Retinal Detachment.
Invest Ophthalmol Vis Sci. 2025;66:17.
PubMed Abstract available

PEI X, Ba M, Yang T, Xuan S, et al
Leptin Receptor Deficiency-Associated Diabetes Disrupts Lacrimal Gland Circadian Rhythms and Contributes to Dry Eye Syndrome.
Invest Ophthalmol Vis Sci. 2025;66:19.
PubMed Abstract available

OLIVEIRA S, Guimaraes P, Campos EJ, Fernandes R, et al
Retinal OCT-Derived Texture Features as Potential Biomarkers for Early Diagnosis and Progression of Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2025;66:7.
PubMed Abstract available

WONGCHAISUWAT N, Wang J, Hormel TT, Jia Y, et al
Slab-Specific Projection-Resolved Optical Coherence Tomography Angiography for Enhancing En Face Polyp Detection in Polypoidal Choroidal Vasculopathy.
Invest Ophthalmol Vis Sci. 2025;66:9.
PubMed Abstract available

KAYEMBE MULUMBA B, Leffondre K, Joly P, Delyfer MN, et al
Unveiling Statins and Genetics in Age-Related Macular Degeneration Progression: What Is the Appropriate Modeling Strategy?
Invest Ophthalmol Vis Sci. 2025;66:25.
PubMed

CAO Q, Xu W, Chen X, Luo G, et al
PRMT1-Mediated Arginine Methylation Promotes Corneal Epithelial Wound Healing via Epigenetic Regulation of ANXA3.
Invest Ophthalmol Vis Sci. 2025;66:22.
PubMed Abstract available

LIU C, Wang X, Ong HS, Ang M, et al
Aqueous Proteomic and Metabolomic Profiles in Low-Energy vs High-Energy Femtosecond Laser-Assisted Cataract Surgery.
Invest Ophthalmol Vis Sci. 2025;66:10.
PubMed Abstract available

CHEN J, Zhu T, Huang Z, Jia R, et al
The Value of Orbital Exenteration for Eyelid Sebaceous Carcinoma in Stages II to IV: A Cohort Study of 78 Patients.
Invest Ophthalmol Vis Sci. 2025;66:40.
PubMed Abstract available

CHATILA A, Ea V, Izuagbe S, Hoang LQ, et al
Influence of Lens Power on IOL/Posterior Lens Capsule Interactions and IOL's PCO Potential.
Invest Ophthalmol Vis Sci. 2025;66:41.
PubMed Abstract available

FRY BC, Arciero JC, Gyurek C, Albright A, et al
Using a Theoretical Model to Assess the Impact of Vascular Risk Factors on Autoregulation in the Retina.
Invest Ophthalmol Vis Sci. 2025;66:42.
PubMed Abstract available

SU CC, Desikan V, Betsch K, Shim MS, et al
Tubulin Acetylation Enhances Microtubule Stability in Trabecular Meshwork Cells Under Mechanical Stress.
Invest Ophthalmol Vis Sci. 2025;66:43.
PubMed Abstract available

BENEDETTO MM, Malcolm M, Bruera MG, Penazzi LG, et al
Stress Granule Induction in Rat Retinas Damaged by Constant LED Light.
Invest Ophthalmol Vis Sci. 2025;66:38.
PubMed Abstract available

MURSALIN MH, Coburn PS, Longoria-Gonzalez L, Astley R, et al
Novel Anti-Microbial/Anti-Inflammatory Combination Improves Clinical Outcome of Bacillus cereus Endophthalmitis.
Invest Ophthalmol Vis Sci. 2025;66:39.
PubMed Abstract available

MONTESANO G, Rabiolo A, Ometto G, Crabb DP, et al
Relationship Between Intraocular Pressure and the True Rate of Functional and Structural Progression in the United Kingdom Glaucoma Treatment Study.
Invest Ophthalmol Vis Sci. 2025;66:32.
PubMed Abstract available

YANG J, Zhong J, Fu Z, He D, et al
Piezo1 Enhances Macrophage Phagocytosis and Pyrin Activation to Ameliorate Fungal Keratitis.
Invest Ophthalmol Vis Sci. 2025;66:33.
PubMed Abstract available

WEI Y, Sun M, Zhang X, Zhang C, et al
S100A8/A9 Promotes Dendritic Cell-Mediated Th17 Cell Response in Sjogren's Dry Eye Disease by Regulating the Acod1/STAT3 Pathway.
Invest Ophthalmol Vis Sci. 2025;66:35.
PubMed Abstract available

LIU H, Zhang X, Wang Q, Li B, et al
A Comprehensive Analysis of Sex-Biased Gene Expression in the Aging Human Retina Through a Combination of Single-Cell and Bulk RNA Sequencing.
Invest Ophthalmol Vis Sci. 2025;66:28.
PubMed Abstract available

GENG W, Li P, Zhang G, Zhong R, et al
Targeted Activation of OGG1 Inhibits Paraptosis in Lens Epithelial Cells of Early Age-Related Cortical Cataract.
Invest Ophthalmol Vis Sci. 2025;66:29.
PubMed Abstract available

RIDDELL N, Murphy MJ, Zahra S, Robertson-Dixon I, et al
Broadband Long Wavelength Light Promotes Myopic Eye Growth and Alters Retinal Responses to Light Offset in Chick.
Invest Ophthalmol Vis Sci. 2025;66:30.
PubMed Abstract available

GELORMINI F, Ricardi F, Parisi G, Vallino V, et al
Visual Performance and Predictive OCT Biomarkers in Epiretinal Membrane Assessment: Beyond Distance Visual Acuity.
Invest Ophthalmol Vis Sci. 2025;66:31.
PubMed Abstract available

Erratum in: Glaucoma Patients Have a Lower Abundance of Butyrate-Producing Taxa in the Gut.
Invest Ophthalmol Vis Sci. 2025;66:45.
PubMed

XIAO Y, McGhee CNJ, Zhang J
Posterior Limbal Mesenchymal Stromal Cells Promote Proliferation and Stemness of Transition Zone Cells: A Novel Insight Into Corneal Endothelial Rejuvenation.
Invest Ophthalmol Vis Sci. 2025;66:44.
PubMed Abstract available

Erratum in: Levels of the HtrA1 Protein in Serum and Vitreous Humor Are Independent of Genetic Risk for Age-Related Macular Degeneration at the 10q26 Locus.
Invest Ophthalmol Vis Sci. 2025;66:37.
PubMed

Erratum in: Inflammatory Cytokines Induce Apoptosis of Corneal Endothelium through Nitric Oxide.
Invest Ophthalmol Vis Sci. 2025;66:34.
PubMed

MOON L, Kaur P, Wang J, Sodhi A, et al
Mechanical Strain of Corneal Epithelium Influences the Expression of Genes Implicated in Keratoconus.
Invest Ophthalmol Vis Sci. 2025;66:52.
PubMed Abstract available

DEMER JL, Clark RA, Suh SY, Giaconi JA, et al
Eye Movements and the Intraorbital Subarachnoid Space: Potential Contribution of Altered Cerebrospinal Fluid Pumping in Optic Neuropathies.
Invest Ophthalmol Vis Sci. 2025;66:53.
PubMed Abstract available

LIN JB, Apte RS
The Landscape of Vascular Endothelial Growth Factor Inhibition in Retinal Diseases.
Invest Ophthalmol Vis Sci. 2025;66:47.
PubMed Abstract available

CURCIO CA, Messinger JD, Berlin A, Sloan KR, et al
Fundus Autofluorescence Variation in Geographic Atrophy of Age-Related Macular Degeneration: A Clinicopathologic Correlation.
Invest Ophthalmol Vis Sci. 2025;66:49.
PubMed Abstract available

HO WT, Chang JS, Lei CJ, Chen TC, et al
ROCK Inhibitor Enhances Resilience Against Metabolic Stress Through Increasing Bioenergetic Capacity in Corneal Endothelial Cells.
Invest Ophthalmol Vis Sci. 2025;66:51.
PubMed Abstract available

WANG X, Wang X, Zhao Z, Wang Q, et al
DNA-Dependent Protein Kinase Catalytic Subunit Prevents Ferroptosis in Retinal Pigment Epithelial Cells.
Invest Ophthalmol Vis Sci. 2025;66:50.
PubMed Abstract available

FJAERVOLL KA, Fjaervoll HK, Yang M, Bair J, et al
Pyrimidinergic P2Y1-Like Nucleotide Receptors Are Functional in Rat Conjunctival Goblet Cells.
Invest Ophthalmol Vis Sci. 2025;66:46.
PubMed Abstract available

LIU Q, Xia LX, Yi WZ, Wu YN, et al
Inhibition of Retinal Neovascularization by BEZ235: Targeting the Akt/4EBP1/Cyclin D1 Pathway in Endothelial Cells.
Invest Ophthalmol Vis Sci. 2025;66:66.
PubMed Abstract available

VOGELS DHJ, Brekelmans J, Mohren R, Vos NRN, et al
Proteomics Reveals Mechanisms of Delayed Keratoconus Progression: A Study of Corneas Following Two Light-Activated Crosslinking Treatments.
Invest Ophthalmol Vis Sci. 2025;66:64.
PubMed Abstract available

WANG Y, Wang P, Yi Z, Ouyang J, et al
ABCA4 Deep Intronic Variants Contributed to Nearly Half of Unsolved Stargardt Cases With a Milder Phenotype.
Invest Ophthalmol Vis Sci. 2025;66:65.
PubMed Abstract available

YING Q, Luo H, Xie Z, Huang Y, et al
SIRT4 Protects Retina Against Excitotoxic Injury by Promoting OPA1-Mediated Muller Glial Cell Mitochondrial Fusion and GLAST Expression.
Invest Ophthalmol Vis Sci. 2025;66:62.
PubMed Abstract available

XU W, Cao L, Liu H
CAMK2D and Complement Factor I-Involved Calcium/Calmodulin Signaling Modulates Sodium Iodate-Induced Mouse Retinal Degeneration.
Invest Ophthalmol Vis Sci. 2025;66:63.
PubMed Abstract available

NISHIDA T, Shoji T, Weinreb RN, Yamaguchi S, et al
Horizontal Gaze Tolerance and Its Effects on Visual Sensitivity in Glaucoma.
Invest Ophthalmol Vis Sci. 2025;66:59.
PubMed Abstract available

KUMAR NR, Khamar P, Kannan R, Padmanabhan A, et al
Distinct Ocular Surface Microbiome in Keratoconus Patients Correlate With Local Immune Dysregulation.
Invest Ophthalmol Vis Sci. 2025;66:60.
PubMed Abstract available

KIM MS, Kim H, Lee HK, Kim CY, et al
Artificial Intelligence in Predicting Ocular Hypertension After Descemet Membrane Endothelial Keratoplasty.
Invest Ophthalmol Vis Sci. 2025;66:61.
PubMed Abstract available

LIN Z, Christaras D, Duarte-Toledo R, Yang Z, et al
Dynamic Accommodation Responses in Subjects Wearing Myopia Control Spectacles Modifying Peripheral Refraction.
Invest Ophthalmol Vis Sci. 2025;66:55.
PubMed Abstract available

WANG L, Li Y, Niu T, Deng J, et al
Simvastatin-Induced Ferroptosis in Orbital Fibroblasts in Graves' Ophthalmopathy.
Invest Ophthalmol Vis Sci. 2025;66:56.
PubMed Abstract available

OTERO-MARQUEZ O, Haq A, Muncharaz Duran L, Bellis J, et al
Preferential Sites of Retinal Capillary Occlusion in Sickle Cell Disease.
Invest Ophthalmol Vis Sci. 2025;66:57.
PubMed Abstract available

LIAO D, Wang J, Zhang X, Li R, et al
ENO2-Regulated Glycolysis in Endothelial Cells Contributes to FGF2-Induced Retinal Neovascularization.
Invest Ophthalmol Vis Sci. 2025;66:58.
PubMed Abstract available

December 2024

MULFAUL K, Khan AH, Schwarte SG, Voigt AP, et al
Elevation of Granulocyte Colony Stimulating Factor in Human AMD Donor RPE-Choroid.
Invest Ophthalmol Vis Sci. 2024;65:15.
PubMed Abstract available

ARDON M, Nguyen L, Chen R, Rogers J, et al
Onset and Progression of Disease in Nonhuman Primates With PDE6C Cone Disorder.
Invest Ophthalmol Vis Sci. 2024;65:16.
PubMed Abstract available

ZUO X, Zeng H, Yang X, He D, et al
Atg5-Mediated Lipophagy Induces Ferroptosis in Corneal Epithelial Cells in Dry Eye Disease.
Invest Ophthalmol Vis Sci. 2024;65:12.
PubMed Abstract available

SAEED A, Guymer RH, Hadoux X, Jannaud M, et al
Longitudinal Changes of Visual Sensitivity With Geographic Atrophy Progression Assessed by Defect-Mapping Microperimetry.
Invest Ophthalmol Vis Sci. 2024;65:13.
PubMed Abstract available

CANCELA MB, Winter U, Zugbi S, Dinardi M, et al
Mimicking Retinoblastoma Treatment With Repeated Topotecan or Melphalan Develops Cross-Resistance to Classic Agents But Not to Repurposed Drugs.
Invest Ophthalmol Vis Sci. 2024;65:14.
PubMed Abstract available

QUAGRAINE IM, Murray J, Cakir GB, Beylergil SB, et al
Evaluating Eye Tracking During Dichoptic Video Viewing With Varied Fellow Eye Contrasts in Amblyopia.
Invest Ophthalmol Vis Sci. 2024;65:11.
PubMed Abstract available

WYNNE N, Jiang YY, Aleman TS, Morgan JIW, et al
Retinal Sensitivity in Comparison to Cone Density in Choroideremia.
Invest Ophthalmol Vis Sci. 2024;65:6.
PubMed Abstract available

TOMITA R, Smith CA, Dyachok OM, Sharpe GP, et al
Sequence and Detectability of Changes in Macular Ganglion Cell Layer Thickness and Perfusion Density in Early Glaucoma.
Invest Ophthalmol Vis Sci. 2024;65:8.
PubMed Abstract available

POELS MMF, de Wit GC, Bijveld MMC, van Genderen MM, et al
Natural Course of Refractive Error in Congenital Stationary Night Blindness: Implications for Myopia Treatment.
Invest Ophthalmol Vis Sci. 2024;65:9.
PubMed Abstract available

CALTON MA, Croze RH, Burns C, Beliakoff G, et al
Design and Characterization of a Novel Intravitreal Dual-Transgene Genetic Medicine for Neovascular Retinopathies.
Invest Ophthalmol Vis Sci. 2024;65:1.
PubMed Abstract available

BORRELLI E, Cappellani F, Pulido JS, Pauleikhoff D, et al
The Umbra and the Penumbra: Longitudinal Effects of Geographic Atrophy in AMD on the Outer Choroid by Imaging Analysis and Histopathological Correlation.
Invest Ophthalmol Vis Sci. 2024;65:2.
PubMed Abstract available

LASPAS P, Hartmann A, Scholz I, Hoffmann EM, et al
Change in Systemic Medication and its Influence on Intraocular Pressure - Results From the Gutenberg Health Study.
Invest Ophthalmol Vis Sci. 2024;65:4.
PubMed Abstract available

SHANG F, Schallek J
Characterization of the Retinal Circulation of the Mouse.
Invest Ophthalmol Vis Sci. 2024;65:3.
PubMed Abstract available

ZHA Z, Xiao D, Liu Z, Peng F, et al
Endoplasmic Reticulum Stress Induces ROS Production and Activates NLRP3 Inflammasome Via the PERK-CHOP Signaling Pathway in Dry Eye Disease.
Invest Ophthalmol Vis Sci. 2024;65:34.
PubMed Abstract available

SEDDON JM, De D, Grunenkovaite L, Ferrara D, et al
Clinical and Imaging Characteristics of PRPH2 Retinopathies in a Longitudinal Cohort and Diagnostic Implications.
Invest Ophthalmol Vis Sci. 2024;65:31.
PubMed Abstract available

ALEMAN TS, Roman AJ, Uyhazi KE, Jiang YY, et al
Retinal Degeneration Associated With Biallelic RDH12 Variants: Longitudinal Evaluation of Retinal Structure and Visual Function in Pediatric Patients.
Invest Ophthalmol Vis Sci. 2024;65:30.
PubMed Abstract available

ACOTT TS, Fautsch MP, Mao W, Ethier CR, et al
Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches.
Invest Ophthalmol Vis Sci. 2024;65:32.
PubMed Abstract available

VAUGHAN M, Tay N, Kalitzeos A, Kane T, et al
Changes in Waveguiding Cone Photoreceptors and Color Vision in Patients With Diabetes Mellitus.
Invest Ophthalmol Vis Sci. 2024;65:28.
PubMed Abstract available

RAHMAN B, Anderson DMG, Chen C, Liu J, et al
Sphingolipid Levels and Processing of the Retinyl Chromophore in the Retina of a Mouse Model of Niemann-Pick Disease.
Invest Ophthalmol Vis Sci. 2024;65:24.
PubMed Abstract available

YANG HS, Choi S, Kim S, Min CH, et al
Epiretinal Membrane: Correlations Among Clinical, Immunohistochemical, and Biochemical Features and Their Prognostic Implications.
Invest Ophthalmol Vis Sci. 2024;65:25.
PubMed Abstract available

JIANG Q, Li Z, Huang Y, Huang Z, et al
Itaconate Ameliorates Experimental Autoimmune Uveitis by Modulating Teff/Treg Cell Imbalance Via the DNAJA1/CDC45 Axis.
Invest Ophthalmol Vis Sci. 2024;65:23.
PubMed Abstract available

YANG Y, Fan C, Zhang Y, Kang T, et al
Untargeted Metabolomics Reveals the Role of Lipocalin-2 in the Pathological Changes of Lens and Retina in Diabetic Mice.
Invest Ophthalmol Vis Sci. 2024;65:19.
PubMed Abstract available

LAI C, Su T, Cao J, Li Q, et al
Retinal Neurovascular Impairment in Full-Course Diabetic Retinopathy: The Guangdong Diabetic Retinopathy Multiple-Omics Study.
Invest Ophthalmol Vis Sci. 2024;65:20.
PubMed Abstract available

YU Y, Cui S, He Y, Zhang J, et al
Early Diabetic Retinopathy Evaluation With OCTA: A Study on Vascular Branching and Fragmentation.
Invest Ophthalmol Vis Sci. 2024;65:21.
PubMed Abstract available

BISWAS S, Busoy JMF, Barathi VA, Muralidharan AR, et al
Interactions Between High-Intensity Light and Unrestricted Vision in the Drive for Hyperopia.
Invest Ophthalmol Vis Sci. 2024;65:22.
PubMed Abstract available

FAN C, Yang Y, You M, Chen Z, et al
Mefunidone Inhibits Inflammation, Oxidative Stress, and Epithelial-Mesenchymal Transition in Lens Epithelial Cells.
Invest Ophthalmol Vis Sci. 2024;65:17.
PubMed Abstract available

LI J, Chen Y, Wang W, Zhang Y, et al
Linking Iris Cis-Regulatory Variants to Primary Angle-Closure Glaucoma Via Clinical Imaging and Multiomics.
Invest Ophthalmol Vis Sci. 2024;65:18.
PubMed Abstract available

GLASS J, Robinson R, Edupuganti N, Altman J, et al
Proteomic Alterations in Retinal Muller Glial Cells Lacking Interleukin-6 Receptor: A Comprehensive Analysis.
Invest Ophthalmol Vis Sci. 2024;65:33.
PubMed Abstract available

BELAMKAR A, Luo Q, Mahajan N, Abhyankar S, et al
Characterization of the Ocular Phenotype in a Col4a3 Knockout Mouse Model of Alport Syndrome.
Invest Ophthalmol Vis Sci. 2024;65:29.
PubMed Abstract available

WILLIAMS BL, Zouache MA, Hageman GS
Author Response: Levels of the HtrA1 Protein in Serum and Vitreous Humor Are Independent of Genetic Risk for Age-Related Macular Degeneration at the 10q26 Locus.
Invest Ophthalmol Vis Sci. 2024;65:26.
PubMed

PAN Y, Iwata T
Letter to the Editor: Levels of the HtrA1 Protein in Serum and Vitreous Humor Are Independent of Genetic Risk for Age-Related Macular Degeneration at the 10q26 Locus.
Invest Ophthalmol Vis Sci. 2024;65:27.
PubMed

COHEN-DAVIDI E, Feinstein V, Knyazer B, Beit-Yannai E, et al
Integrated Profiling of Extracellular Vesicle microRNA Impact on Trabecular Meshwork mRNA Expression: Insights From Microarray Analysis.
Invest Ophthalmol Vis Sci. 2024;65:38.
PubMed Abstract available

SUGASINI D, Yalagala PCR, Park JC, Ma G, et al
Retinal Docosahexaenoic Acid Is Significantly Reduced in Diabetic Humans and Mice: Possible Relationship to Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2024;65:39.
PubMed Abstract available

JIANG X, Sun K, Fan Y, Xiang Q, et al
Mettl3-Mediated m6A Modification is Essential for Visual Function and Retinal Photoreceptor Survival.
Invest Ophthalmol Vis Sci. 2024;65:40.
PubMed Abstract available

JAKOBSEN TS, Adsersen RL, Askou AL, Corydon TJ, et al
Functional Roles of Pigment Epithelium-Derived Factor in Retinal Degenerative and Vascular Disorders: A Scoping Review.
Invest Ophthalmol Vis Sci. 2024;65:41.
PubMed Abstract available

GOERDT L, Rodriguez Garcia JL, Kunzel SH, Pfau K, et al
Prognostic Relevance of Relative Ellipsoid Zone Reflectivity for Ellipsoid Zone Loss in Macular Telangiectasia Type 2.
Invest Ophthalmol Vis Sci. 2024;65:36.
PubMed Abstract available

PETERSEN L, Bek T
Systemic Hypoxia and Interventions on Nitric Oxide Metabolism Affect Retinal Vasomotion in Healthy Subjects.
Invest Ophthalmol Vis Sci. 2024;65:35.
PubMed Abstract available

YU J, Zhang Y, Ho M, Zhang XJ, et al
Association of Metabolomics With Incidence of Age-Related Macular Degeneration: The UK Biobank Study.
Invest Ophthalmol Vis Sci. 2024;65:43.
PubMed Abstract available

VIGGIANO P, Boscia G, Giannaccare G, Santoro M, et al
Topographical Quantification of Hyper-Reflective Foci May Predict the Development of Macular Atrophy in Patients With Neovascular Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2024;65:45.
PubMed Abstract available

HUBER KL, Stino H, Steiner I, Fuchs P, et al
Real-World Outcomes After Switch From Aflibercept to Faricimab in Eyes With Diabetic Macular Edema.
Invest Ophthalmol Vis Sci. 2024;65:46.
PubMed Abstract available

Erratum in: Influencing Factors on Pupillary Light Responses as a Biomarker for Local Retinal Function in a Large Normative Cohort.
Invest Ophthalmol Vis Sci. 2024;65:44.
PubMed

November 2024

ZHANG M, Zhang R, Hao J, Zhao X, et al
Quercetin Alleviates Scleral Remodeling Through Inhibiting the PERK-EIF2alpha Axis in Experiment Myopia.
Invest Ophthalmol Vis Sci. 2024;65:11.
PubMed Abstract available

PAPP FR, Katko M, Csiki R, Galgoczi E, et al
Characteristics of Hyaluronan Metabolism During Myofibroblast Differentiation in Orbital Fibroblasts.
Invest Ophthalmol Vis Sci. 2024;65:13.
PubMed Abstract available

AWAD AM, Seetharaman ATM, Hossain MS, Elshaer SL, et al
Cysteine Leukotriene Receptor Antagonist-Montelukast Effects on Diabetic Retinal Microvascular Endothelial Cells Curtail Autophagy.
Invest Ophthalmol Vis Sci. 2024;65:15.
PubMed Abstract available

RODENBERG RR, Spadafora D, Fitzpatrick S, Daly G, et al
gammadelta T17 Cells Regulate the Acute Antiviral Response of NK Cells in HSV-1-Infected Corneas.
Invest Ophthalmol Vis Sci. 2024;65:16.
PubMed Abstract available

EPARDO D, Balderas-Marquez JE, Rodriguez-Arzate CA, Thebault SC, et al
Growth Hormone Neuroprotective Effects After an Optic Nerve Crush in the Male Rat.
Invest Ophthalmol Vis Sci. 2024;65:17.
PubMed Abstract available

YAO X, Li Z, Lei Y, Liu Q, et al
Single-Cell Multiomics Profiling Reveals Heterogeneity of Muller Cells in the Oxygen-Induced Retinopathy Model.
Invest Ophthalmol Vis Sci. 2024;65:8.
PubMed Abstract available

WU M, Zhao X, Peng S, Zhang X, et al
Progressive Optic Neuropathy in Hydrocephalic Ccdc13 Mutant Mice Caused by Impaired Axoplasmic Transport at the Optic Nerve Head.
Invest Ophthalmol Vis Sci. 2024;65:5.
PubMed Abstract available

MAITI S, Gowtham L, Rudraprasad D, Dave VP, et al
Age-Associated Alterations in the Metabolome of Human Vitreous in Bacterial Endophthalmitis.
Invest Ophthalmol Vis Sci. 2024;65:6.
PubMed Abstract available

ZHANG X, Li T, Zhang R, Li J, et al
Downregulation of SARM1 Protects Retinal Ganglion Cell Axonal and Somal Degeneration Via JNK Activation in a Glaucomatous Model of Ocular Hypertension.
Invest Ophthalmol Vis Sci. 2024;65:7.
PubMed Abstract available

BANSAL M, Wang B, Waxman S, Zhong F, et al
Proposing a Methodology for Axon-Centric Analysis of IOP-Induced Mechanical Insult.
Invest Ophthalmol Vis Sci. 2024;65:1.
PubMed Abstract available

HANSON JVM, Single S, Eberle RB, Kana V, et al
Retinal Function in Advanced Multiple Sclerosis.
Invest Ophthalmol Vis Sci. 2024;65:2.
PubMed Abstract available

MA S, Huis In't Veld RV, de Los Pinos E, Ossendorp FA, et al
Treatment of Conjunctival Melanoma Cell Lines With a Light-Activated Virus-Like Drug Conjugate Induces Immunogenic Cell Death.
Invest Ophthalmol Vis Sci. 2024;65:3.
PubMed Abstract available

ZHANG J, Ruan L, Jiang C, Yang Q, et al
Midperipheral Microvascular Defects and Their Associations With Vitreoretinal Abnormalities in Early-Stage Familial Exudative Vitreoretinopathy.
Invest Ophthalmol Vis Sci. 2024;65:4.
PubMed Abstract available

PAL-GHOSH S, Karpinski BA, Datta-Majumdar H, Datta S, et al
Mechanisms Regulating Mitochondrial Transfer in Human Corneal Epithelial Cells.
Invest Ophthalmol Vis Sci. 2024;65:10.
PubMed Abstract available

RODRIGUEZ-LOPEZ R, Webb JN, Erdi M, Kofinas P, et al
Determining the Relationship Between Corneal Stiffening and Tissue Dehydration After Corneal Cross-Linking.
Invest Ophthalmol Vis Sci. 2024;65:14.
PubMed Abstract available

YU Y, Chen H, Wang Z, Ye Y, et al
Exploring the Relationship Between Refractive Errors and Common Chronic Diseases Via Blood Biochemistry Tests: A Large Prospective Cohort Study.
Invest Ophthalmol Vis Sci. 2024;65:26.
PubMed Abstract available

XU Y, Liu X, Wu N, Long Y, et al
Investigating Microperimetric Features in Bietti Crystalline Dystrophy Patients: A Cross-Sectional Longitudinal Study in a Large Cohort.
Invest Ophthalmol Vis Sci. 2024;65:27.
PubMed Abstract available

RODRIGUEZ-MARTINEZ L, Rodriguez-Fernandez CA, Rodriguez Lemos O, de Domingo B, et al
Potential Prognostic Protein Biomarkers in Tears From Noninfectious Uveitis Patients Under Biologic Treatment as a Prelude to Personalized Medicine.
Invest Ophthalmol Vis Sci. 2024;65:29.
PubMed Abstract available

TAN B, Shah JN, McNabb RP, Jayaraman S, et al
Distortion-Corrected Posterior Ocular Shape in Myopic Eyes Assessed by Ultrawide OCT Detects Deformations Associated With Vision-Threatening Changes.
Invest Ophthalmol Vis Sci. 2024;65:22.
PubMed Abstract available

HAN J, Chear S, Talbot J, Swier V, et al
Genetic and Cellular Basis of Impaired Phagocytosis and Photoreceptor Degeneration in CLN3 Disease.
Invest Ophthalmol Vis Sci. 2024;65:23.
PubMed Abstract available

XU Z, Tan JK, Vetrivel K, Jiang X, et al
The Electroretinogram I-Wave, a Component Originating in the Retinal OFF-Pathway, Associates With a Myopia Genetic Risk Polymorphism.
Invest Ophthalmol Vis Sci. 2024;65:21.
PubMed Abstract available

GIESSER SD, Turgut F, Saad A, Zoellin JR, et al
Evaluating the Impact of Retinal Vessel Segmentation Metrics on Retest Reliability in a Clinical Setting: A Comparative Analysis Using AutoMorph.
Invest Ophthalmol Vis Sci. 2024;65:24.
PubMed Abstract available

Erratum in: Smoking, Corneal Biomechanics, and Glaucoma: Results From Two Large Population-Based Cohorts.
Invest Ophthalmol Vis Sci. 2024;65:18.
PubMed

Erratum in: IMI - Defining and Classifying Myopia: A Proposed Set of Standards for Clinical and Epidemiologic Studies.
Invest Ophthalmol Vis Sci. 2024;65:19.
PubMed

RAKSHIT A, Majhi D, Schmid KL, Warkad V, et al
Fine Motor Skills, Reading Speed, and Self-Reported Quality of Life in Adults With Amblyopia and/or Strabismus.
Invest Ophthalmol Vis Sci. 2024;65:48.
PubMed Abstract available

BRENNAN NA, Cheng X, Bullimore MA
Adult Myopia Progression.
Invest Ophthalmol Vis Sci. 2024;65:49.
PubMed Abstract available

ANTONETTI DA, Lin CM, Shanmugam S, Hager H, et al
Diabetes Renders Photoreceptors Susceptible to Retinal Ischemia-Reperfusion Injury.
Invest Ophthalmol Vis Sci. 2024;65:46.
PubMed Abstract available

LOELIGER J, Lhotte R, Gelfman S, Stahl EA, et al
The Impact of HLA-A29 Homozygosity and of the Second HLA-A Allele on Susceptibility and Severity of Birdshot Chorioretinitis.
Invest Ophthalmol Vis Sci. 2024;65:47.
PubMed Abstract available

HAMMER J, Roppenack P, Yousuf S, Machate A, et al
Blind But Alive - Congenital Loss of atoh7 Disrupts the Visual System of Adult Zebrafish.
Invest Ophthalmol Vis Sci. 2024;65:42.
PubMed Abstract available

QUILLEN SE, Kimball EC, Ritter-Gordy KA, Du L, et al
The Mechanisms of Neuroprotection by Topical Rho Kinase Inhibition in Experimental Mouse Glaucoma and Optic Neuropathy.
Invest Ophthalmol Vis Sci. 2024;65:43.
PubMed Abstract available

HANYUDA A, Raita Y, Ninomiya T, Hashimoto K, et al
Metabolomic Profiling of Open-Angle Glaucoma Etiologic Endotypes: Tohoku Multi-Omics Glaucoma Study.
Invest Ophthalmol Vis Sci. 2024;65:44.
PubMed Abstract available

LIANG D, Du B, Leung TW, Liu Z, et al
Impact of Astigmatism on Axial Elongation in School-Age Children: A Five-Year Population-Based Study in Tianjin, China.
Invest Ophthalmol Vis Sci. 2024;65:45.
PubMed Abstract available

SADEGHI E, Valsecchi N, Ibrahim MN, Du K, et al
Three-Dimensional Choroidal Vessels Assessment in Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2024;65:39.
PubMed Abstract available

PATRICK CC, Roztocil E, Husain F, Feldon SE, et al
Tapinarof, an Aryl Hydrocarbon Receptor Ligand, Mitigates Fibroblast Activation in Thyroid Eye Disease: Implications for Novel Therapy.
Invest Ophthalmol Vis Sci. 2024;65:40.
PubMed Abstract available

ONISHI A, Tsunekawa Y, Mandai M, Ishimaru A, et al
Optimization of HITI-Mediated Gene Insertion for Rhodopsin and Peripherin-2 in Mouse Rod Photoreceptors: Targeting Dominant Retinitis Pigmentosa.
Invest Ophthalmol Vis Sci. 2024;65:38.
PubMed Abstract available

LIUKKONEN M, Helotera H, Siintamo L, Ghimire B, et al
Oxidative Stress and Inflammation-Related mRNAs Are Elevated in Serum of a Finnish Wet AMD Cohort.
Invest Ophthalmol Vis Sci. 2024;65:30.
PubMed Abstract available

MA DJ, Kim SM, Choi JM
Associations of Retinal Vessel Geometry and Optical Coherence Tomography Angiography Metrics With Choroidal Metrics in Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2024;65:31.
PubMed Abstract available

PARK SH, Choi SH, Park HY, Ko J, et al
Role of Lysyl Oxidase-Like Protein 3 in the Pathogenesis of Graves' Orbitopathy in Orbital Fibroblasts.
Invest Ophthalmol Vis Sci. 2024;65:33.
PubMed Abstract available

SOTANI Y, Imai H, Yamada H, Miki A, et al
High Intraocular Concentration of Fibrinogen Regulates Retinal Function Via the ICAM-1 Pathway.
Invest Ophthalmol Vis Sci. 2024;65:34.
PubMed Abstract available

YANG X, Zhong X, Lin H, Huang AJW, et al
Deletion of Fgfr2 in Ductal Basal Epithelium With Tamoxifen Induces Obstructive Meibomian Gland Dysfunction.
Invest Ophthalmol Vis Sci. 2024;65:36.
PubMed Abstract available

LI Y, Ge L, Ren B, Zhang X, et al
De-Differentiation of Corneal Epithelial Cells Into Functional Limbal Epithelial Stem Cells After the Ablation of Innate Stem Cells.
Invest Ophthalmol Vis Sci. 2024;65:32.
PubMed Abstract available

ZHENG X, Wang C, Fan Y, Hong Y, et al
Restoration of Corneal Stiffness in Rabbits Following Withdrawal of Travoprost.
Invest Ophthalmol Vis Sci. 2024;65:35.
PubMed Abstract available

EBRAHIMI S, Bedggood P, Ding Y, Metha A, et al
A High-Fidelity Computational Model for Predicting Blood Cell Trafficking and 3D Capillary Hemodynamics in Retinal Microvascular Networks.
Invest Ophthalmol Vis Sci. 2024;65:37.
PubMed Abstract available

JOSAN AS, Taylor LJ, Xue K, Cehajic-Kapetanovic J, et al
Ranked Importance of Visual Function Outcome Measures in Choroideremia Clinical Trials.
Invest Ophthalmol Vis Sci. 2024;65:58.
PubMed Abstract available

OBIED B, Richard S, Zahavi A, Kreizman-Shefer H, et al
Cobalt Toxicity Induces Retinopathy and Optic Neuropathy in Mice.
Invest Ophthalmol Vis Sci. 2024;65:59.
PubMed Abstract available

DALVIN LA, Andrews-Pfannkoch CM, Miley DR, Hogenson TL, et al
Novel Uveal Melanoma Patient-Derived Organoid Models Recapitulate Human Disease to Support Translational Research.
Invest Ophthalmol Vis Sci. 2024;65:60.
PubMed Abstract available

HUANG Y, Wang L, Jin H
cRGD-Conjugated Bilirubin Nanoparticles Alleviate Dry Eye Disease Via Activating the PINK1-Mediated Mitophagy.
Invest Ophthalmol Vis Sci. 2024;65:55.
PubMed Abstract available

LIN X, Zheng C, Cong J, Feng Q, et al
Metabolic Characteristics of Sclera in Lens-Induced Myopic Guinea Pigs.
Invest Ophthalmol Vis Sci. 2024;65:51.
PubMed Abstract available

OLUFSEN ME, Hannibal J, Sorensen NB, Christiansen AT, et al
Subretinal Amniotic Membrane Transplantation in a Porcine Model of Retinal Hole.
Invest Ophthalmol Vis Sci. 2024;65:52.
PubMed Abstract available

JASKOLL S, Kramer A, Elbaz-Hayoun S, Rinsky B, et al
Adult Onset Foveomacular Vitelliform Dystrophy Shows Genetic Overlap With Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2024;65:53.
PubMed Abstract available

CHUANGSUWANICH T, Tun TA, Braeu FA, Chong RS, et al
Comparing IOP-Induced Scleral Deformations in the Myopic and Myopic Glaucoma Spectrums.
Invest Ophthalmol Vis Sci. 2024;65:54.
PubMed Abstract available

HERNANDEZ BJ, Strain M, Suarez MF, Stamer WD, et al
Small Extracellular Vesicle-Associated MiRNAs in Polarized Retinal Pigmented Epithelium.
Invest Ophthalmol Vis Sci. 2024;65:57.
PubMed Abstract available

October 2024

HEDSTROM J, Nilsson M, Engvall M, Williams PA, et al
Ganglion Cell Complex Thickness and Visual Function in Chronic Leber Hereditary Optic Neuropathy.
Invest Ophthalmol Vis Sci. 2024;65:4.
PubMed Abstract available

ZHONG X, Li H, Tan S, Yang S, et al
Initial Retinal Nerve Fiber Layer Loss and Risk of Diabetic Retinopathy Over a Four-Year Period.
Invest Ophthalmol Vis Sci. 2024;65:5.
PubMed Abstract available

CHEUNG R, Trinh M, Nivison-Smith L
Retinal Pigment Epithelium Curvature Can Predict Late Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2024;65:7.
PubMed Abstract available

CURRO KR, van Nispen RMA, den Braber A, van de Giessen EM, et al
Longitudinal Assessment of Retinal Microvasculature in Preclinical Alzheimer's Disease.
Invest Ophthalmol Vis Sci. 2024;65:2.
PubMed Abstract available

WANG G, Zhu Y, Liu Y, Yang M, et al
Mesenchymal Stem Cells-Derived Exosomal miR-223-3p Alleviates Ocular Surface Damage and Inflammation by Downregulating Fbxw7 in Dry Eye Models.
Invest Ophthalmol Vis Sci. 2024;65:1.
PubMed Abstract available

APPELBAUM T, Santana E, Smith DA, Beltran WA, et al
Glial Cell Responses and Gene Expression Dynamics in Retinas of Treated and Untreated RPE65 Mutant Dogs.
Invest Ophthalmol Vis Sci. 2024;65:18.
PubMed Abstract available

GEIDUSCHEK EK, Bricco EK, McDowell CM
DAMPs Drive Fibroinflammatory Changes in the Glaucomatous ONH.
Invest Ophthalmol Vis Sci. 2024;65:13.
PubMed Abstract available

ZHANG W, Wang X, Tian S, Wang J, et al
Fetuin-B Interacts With Insulin Receptor-beta and Promotes Insulin Resistance in Retina Cells.
Invest Ophthalmol Vis Sci. 2024;65:16.
PubMed Abstract available

YANG H, Reynaud J, Sharpe GP, Jennings D, et al
Diagnostic Performance for Detection of Glaucomatous Structural Damage Using Pixelwise Analysis of Retinal Thickness Measurements.
Invest Ophthalmol Vis Sci. 2024;65:17.
PubMed Abstract available

MECHO-GARCIA M, Arcas-Carbonell M, Orduna-Hospital E, Sanchez-Cano A, et al
Statistical Model of Ocular Wavefronts With Accommodation.
Invest Ophthalmol Vis Sci. 2024;65:12.
PubMed Abstract available

NGUYEN JQN, Drabarek W, Leeflang AMCHJ, Brands T, et al
The Impact of Spliceosome Inhibition in SF3B1-Mutated Uveal Melanoma.
Invest Ophthalmol Vis Sci. 2024;65:11.
PubMed Abstract available

AKIBA R, Tu HY, Hashiguchi T, Takahashi Y, et al
Host-Graft Synapses Form Functional Microstructures and Shape the Host Light Responses After Stem Cell-Derived Retinal Sheet Transplantation.
Invest Ophthalmol Vis Sci. 2024;65:8.
PubMed Abstract available

XIONG F, Arnold BF, Lietman TM, Gonzales JA, et al
Predictors of Discordance Between Dry Eye Symptoms and Signs: Insights From the Sjogren's International Collaborative Clinical Alliance.
Invest Ophthalmol Vis Sci. 2024;65:3.
PubMed Abstract available

KATTA M, Georgiou M, Singh N, Kalitzeos A, et al
Longitudinal Imaging of the Foveal Cone Mosaic in CNGA3-Associated Achromatopsia.
Invest Ophthalmol Vis Sci. 2024;65:6.
PubMed Abstract available

GAO ML, Wang TY, Lin X, Tang C, et al
Retinal Organoid Microenvironment Enhanced Bioactivities of Microglia-Like Cells Derived From HiPSCs.
Invest Ophthalmol Vis Sci. 2024;65:19.
PubMed Abstract available

KIM YW, Sharpe GP, Siber J, Kessler R, et al
Critical Impact of Working Distance on OCT Imaging: Correction of Optical Distortion and Its Effects on Measuring Retinal Curvature.
Invest Ophthalmol Vis Sci. 2024;65:10.
PubMed Abstract available

LI Y, Chang P, Xu L, Zhu Z, et al
TiO2-Nanoparticle-Enhanced Sonodynamic Therapy for Prevention of Posterior Capsular Opacification and Ferroptosis Exploration of Its Mechanism.
Invest Ophthalmol Vis Sci. 2024;65:24.
PubMed Abstract available

KITAHATA S, Inoue T, Tanaka S, Chin JYH, et al
Temporal Changes in the Retinal Pigment Epithelium-Bruch's Membrane Complex Thickness After Autologous Retinal Transplantation in Myopic Eyes.
Invest Ophthalmol Vis Sci. 2024;65:25.
PubMed Abstract available

SUN Z, Stuart KV, Luben RN, Auld AL, et al
Association of Ambient Air Pollution Exposure With Incident Glaucoma: 12-Year Evidence From the UK Biobank Cohort.
Invest Ophthalmol Vis Sci. 2024;65:22.
PubMed Abstract available

BROOKS CJ, Fielding J, White OB, Badcock DR, et al
Exploring the Phenotype and Possible Mechanisms of Palinopsia in Visual Snow Syndrome.
Invest Ophthalmol Vis Sci. 2024;65:23.
PubMed Abstract available

TANG S, Yang J, Xiao B, Wang Y, et al
Aberrant Lipid Metabolism and Complement Activation in Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2024;65:20.
PubMed Abstract available

TANG T, Ren C, Cai Y, Li Y, et al
Lifelong Changes in the Choroidal Thickness, Refractive Status, and Ocular Dimensions in C57BL/6J Mouse.
Invest Ophthalmol Vis Sci. 2024;65:26.
PubMed Abstract available

LAMIRANDE P, Gaffney EA, Gertz M, Maini PK, et al
A First-Passage Model of Intravitreal Drug Delivery and Residence Time-Influence of Ocular Geometry, Individual Variability, and Injection Location.
Invest Ophthalmol Vis Sci. 2024;65:21.
PubMed Abstract available

LECLERCQ B, Mejlachowicz D, Zhu L, Jonet L, et al
Differential Effect of Aldosterone or Mineralocorticoid Receptor Overexpression on Retinal Inflammation.
Invest Ophthalmol Vis Sci. 2024;65:39.
PubMed Abstract available

OU C, Lin Y, Wen J, Zhang H, et al
Roflumilast Attenuates Microglial Senescence and Retinal Inflammatory Neurodegeneration Post Retinal Ischemia Reperfusion Injury Through Inhibiting NLRP3 Inflammasome.
Invest Ophthalmol Vis Sci. 2024;65:38.
PubMed Abstract available

WANG W, Li H, Qian Y, Li M, et al
ALKBH5 Regulates Corneal Neovascularization by Mediating FOXM1 M6A Demethylation.
Invest Ophthalmol Vis Sci. 2024;65:34.
PubMed Abstract available

DANG JN, Wu J, Zheng Y, Bunk JJ, et al
Semi-Automated Analysis of Dome-Shaped Macula in Preterm and Full-Term Infants Using Handheld Swept-Source Optical Coherence Tomography.
Invest Ophthalmol Vis Sci. 2024;65:35.
PubMed Abstract available

GIESSER SD, Turgut F, Saad A, Sommer C, et al
A New Retest-Stable Tortuosity Metric for Retinal Vessel Analyses.
Invest Ophthalmol Vis Sci. 2024;65:30.
PubMed Abstract available

KARPINSKI BA, Pal-Ghosh S, Datta-Majumdar H, Dimri S, et al
ROCK Inhibitor Enhances Neurite Outgrowth In Vitro and Corneal Sensory Nerve Reinnervation In Vivo.
Invest Ophthalmol Vis Sci. 2024;65:31.
PubMed Abstract available

CERVAN-MARTIN M, Higueras-Serrano I, Gonzalez-Munoz S, Guzman-Jimenez A, et al
Comprehensive Evaluation of the Genetic Basis of Keratoconus: New Perspectives for Clinical Translation.
Invest Ophthalmol Vis Sci. 2024;65:32.
PubMed Abstract available

LU ZL, Zhao Y, Lesmes LA, Dorr M, et al
Quantifying the Functional Relationship Between Visual Acuity and Contrast Sensitivity Function.
Invest Ophthalmol Vis Sci. 2024;65:33.
PubMed Abstract available

TORNE O, Oikawa K, Teixeira LBC, Kiland JA, et al
Trabecular Meshwork Abnormalities in a Model of Congenital Glaucoma Due to LTBP2 Mutation.
Invest Ophthalmol Vis Sci. 2024;65:28.
PubMed Abstract available

ZHU L, Chen C, Wu S, Guo H, et al
PAX6-WNK2 Axis Governs Corneal Epithelial Homeostasis.
Invest Ophthalmol Vis Sci. 2024;65:40.
PubMed Abstract available

KURIBAYASHI H, Iwagawa T, Murakami A, Kawamura T, et al
NMNAT1 Is Essential for Human iPS Cell Differentiation to the Retinal Lineage.
Invest Ophthalmol Vis Sci. 2024;65:37.
PubMed Abstract available

YAMAN E, Heyer N, de Paiva CS, Stepp MA, et al
Mouse Corneal Immune Cell Heterogeneity Revealed by Single-Cell RNA Sequencing.
Invest Ophthalmol Vis Sci. 2024;65:29.
PubMed Abstract available

SEITZ IP, Peters T, Reichel F, Bahr A, et al
Optimizing Subretinal Bleb Formation for Visual Streak Involvement in a Porcine Model for Retinal Gene Therapy.
Invest Ophthalmol Vis Sci. 2024;65:41.
PubMed Abstract available

September 2024

CHOI YJ, Kim HM, Na TY, Park KH, et al
Intraocular Concentration of Stem Cell Factor/c-KIT and Galectin-1 in Retinal Diseases.
Invest Ophthalmol Vis Sci. 2024;65:11.
PubMed Abstract available

KUMAR R, Tripathi R, Sinha NR, Mohan RR, et al
RNA-Seq Analysis Unraveling Novel Genes and Pathways Influencing Corneal Wound Healing.
Invest Ophthalmol Vis Sci. 2024;65:13.
PubMed Abstract available

SHANG X, Haner NU, Lincke JB, Pfeiffer V, et al
Long-Term Changes in Lamina Cribrosa Curvature Index After Trabeculectomy in Glaucomatous Eyes.
Invest Ophthalmol Vis Sci. 2024;65:3.
PubMed Abstract available

ZHAO J, Williams MD, Hernandez M, Kuang G, et al
Prognostic Impact of Notch1 Intracellular Domain, P63, and c-MYC in Lacrimal Gland Adenoid Cystic Carcinoma.
Invest Ophthalmol Vis Sci. 2024;65:4.
PubMed Abstract available

TAN RKY, Ng GY, Tun TA, Braeu FA, et al
Iris Morphological and Biomechanical Factors Influencing Angle Closure During Pupil Dilation.
Invest Ophthalmol Vis Sci. 2024;65:7.
PubMed Abstract available

LING Y, Wang Y, Ye J, Luan C, et al
Changes in Intrinsically Photosensitive Retinal Ganglion Cells, Dopaminergic Amacrine Cells, and Their Connectivity in the Retinas of Lid Suture Myopia.
Invest Ophthalmol Vis Sci. 2024;65:8.
PubMed Abstract available

EL EMRANI S, Jansen EJS, Goeman JJ, Termote JUM, et al
Enhancing the Retinopathy Of Prematurity Risk Profile Through Placental Evaluation of Maternal and Fetal Vascular Malperfusion.
Invest Ophthalmol Vis Sci. 2024;65:9.
PubMed Abstract available

GAO F, Li M, Zhu L, Li J, et al
Knockdown of HSPA13 Inhibits TGFbeta1-Induced Epithelial-Mesenchymal Transition of RPE by Suppressing the PI3K/Akt Signaling Pathway.
Invest Ophthalmol Vis Sci. 2024;65:1.
PubMed Abstract available

MA Y, Wu Y, Jin L, Hu L, et al
Association of Retinal Nerve Fiber Layer Thinning With Elevated High Density Lipoprotein Cholesterol in UK Biobank.
Invest Ophthalmol Vis Sci. 2024;65:12.
PubMed Abstract available

Erratum in: Molecular Responses of Anti-VEGF Therapy in Neovascular Age-Related Macular Degeneration: Integrative Insights From Multi-Omics and Clinical Imaging.
Invest Ophthalmol Vis Sci. 2024;65:6.
PubMed

MARTE ME, Kurokawa K, Jung H, Liu Y, et al
Characterizing Presumed Displaced Retinal Ganglion Cells in the Living Human Retina of Healthy and Glaucomatous Eyes.
Invest Ophthalmol Vis Sci. 2024;65:20.
PubMed Abstract available

RUFFINI A, Dvoriashyna M, Govetto A, Romano MR, et al
A Mathematical Model of Interstitial Fluid Flow and Retinal Tissue Deformation in Macular Edema.
Invest Ophthalmol Vis Sci. 2024;65:19.
PubMed Abstract available

ZHANG Y, Ye G, Chen K, Huang S, et al
Peripapillary Retinal Nerve Fiber Layer and Macular Ganglion Cell-Inner Plexiform Layer Parameters and Their Associated Factors in Cynomolgus Macaques.
Invest Ophthalmol Vis Sci. 2024;65:14.
PubMed Abstract available

TODOROKI T, Takeuchi J, Ota H, Nakano Y, et al
Aqueous Humor Cytokine Analysis in Age-Related Macular Degeneration After Switching From Aflibercept to Faricimab.
Invest Ophthalmol Vis Sci. 2024;65:15.
PubMed Abstract available

RIINA N, Harris A, Siesky BA, Ritzer L, et al
Using Multi-Layer Perceptron Driven Diagnosis to Compare Biomarkers for Primary Open Angle Glaucoma.
Invest Ophthalmol Vis Sci. 2024;65:16.
PubMed Abstract available

KLAASSEN L, Jaarsma-Coes MG, Marinkovic M, Luyten GPM, et al
Quantitative Perfusion-Weighted Magnetic Resonance Imaging in Uveal Melanoma.
Invest Ophthalmol Vis Sci. 2024;65:17.
PubMed Abstract available

WILMET B, Michiels C, Zhang J, Callebert J, et al
Loss of ON-Pathway Function in Mice Lacking Lrit3 Decreases Recovery From Lens-Induced Myopia.
Invest Ophthalmol Vis Sci. 2024;65:18.
PubMed Abstract available

TSUBOI K, You QS, Wang J, Guo Y, et al
Quantitative Evaluation of Type 1 and Type 2 Choroidal Neovascularization Components Under Treatment With Projection-Resolved OCT Angiography.
Invest Ophthalmol Vis Sci. 2024;65:32.
PubMed Abstract available

THOMSON K, Karouta C, Ashby R
Administration of Nicotine Can Inhibit Myopic Growth in Animal Models.
Invest Ophthalmol Vis Sci. 2024;65:29.
PubMed Abstract available

LATZ C, Licht A, Mirshahi A, Latz E, et al
Prospective Cytokine Profiling in Aqueous Humor Reveals a Proinflammatory Microenvironment in Highly Dense Nuclear Cataracts.
Invest Ophthalmol Vis Sci. 2024;65:25.
PubMed Abstract available

XIA CH, Lin W, Li R, Xing X, et al
Altered Cell Clusters and Upregulated Aqp1 in Connexin 50 Knockout Lens Epithelium.
Invest Ophthalmol Vis Sci. 2024;65:27.
PubMed Abstract available

SADEGHI A, Subrizi A, Del Amo EM, Urtti A, et al
Mathematical Models of Ocular Drug Delivery.
Invest Ophthalmol Vis Sci. 2024;65:28.
PubMed Abstract available

KRIVOSIC V, Dobbels Z, Duliere C, Zureik A, et al
Multilayer Retinal Correspondence of the Structural and Vascular Anomalies in Eyes With Early Macular Telangiectasia Type 2.
Invest Ophthalmol Vis Sci. 2024;65:24.
PubMed Abstract available

YANG Y, Zhang S, Su S, Yang X, et al
The Effects of STRA6 Regulation of the Circadian Rhythm on Choroidal Neovascularization.
Invest Ophthalmol Vis Sci. 2024;65:21.
PubMed Abstract available

CHEN VY, Pottenburgh JA, Chen SE, Kim S, et al
Plexus-Specific Retinal Capillary Blood Flow Analysis Using Erythrocyte Mediated Angiography and Optical Coherence Tomography Angiography.
Invest Ophthalmol Vis Sci. 2024;65:33.
PubMed Abstract available

HIROTA M, Sasaki K, Kato K, Nakagomi R, et al
Ocular Accommodative and Pupillary Responses During Fixation on Augmented Reality With a Maxwellian Display.
Invest Ophthalmol Vis Sci. 2024;65:30.
PubMed Abstract available

Erratum in: Frequency and Genetic Spectrum of Inherited Retinal Dystrophies in a Large Dutch Pediatric Cohort: The RD5000 Consortium.
Invest Ophthalmol Vis Sci. 2024;65:26.
PubMed

DEVINE T, Elizondo G, Gaston G, Babcock SJ, et al
iPSC-Derived LCHADD Retinal Pigment Epithelial Cells Are Susceptible to Lipid Peroxidation and Rescued by Transfection of a Wildtype AAV-HADHA Vector.
Invest Ophthalmol Vis Sci. 2024;65:22.
PubMed Abstract available

RUDELL JC, McLoon LK
Effects of Short-Term Treatment of Rabbit Extraocular Muscle With Ciliary Neurotrophic Factor.
Invest Ophthalmol Vis Sci. 2024;65:41.
PubMed Abstract available

ZHOU M, Shi ZX, Liu Z, Ke SR, et al
Single-Cell Transcriptomic Analysis Reveals Dynamic Cellular Processes in Corneal Epithelium During Wound Healing in Cynomolgus Monkeys.
Invest Ophthalmol Vis Sci. 2024;65:43.
PubMed Abstract available

NGUYEN BN, Park ASY, McKendrick AM
Eccentricity Dependency of Retinal Electrophysiological Deficits in People With Episodic Migraine.
Invest Ophthalmol Vis Sci. 2024;65:44.
PubMed Abstract available

CONNOLLY E, El-Farouki G, Brennan K, Cahill M, et al
Poor Response to Bevacizumab Correlates With Higher IL-6 and IL-8 Aqueous Cytokines in AMD.
Invest Ophthalmol Vis Sci. 2024;65:37.
PubMed Abstract available

KATO N, Haruta M, Arai R, Sato K, et al
Relationship Between Fluoroquinolone Resistance and Mutations in the Quinolone Resistance-Determining Region in Corynebacterium macginleyi.
Invest Ophthalmol Vis Sci. 2024;65:38.
PubMed Abstract available

KAUR B, Miglioranza Scavuzzi B, Yang M, Yao J, et al
ER Stress and Mitochondrial Perturbations Regulate Cell Death in Retinal Detachment: Exploring the Role of HIF1alpha.
Invest Ophthalmol Vis Sci. 2024;65:39.
PubMed Abstract available

JIANG X, Xu B, Yao S, Wang Z, et al
Delayed Surgical Reversal of Optic Nerve Compression Leads to Exponential Degeneration of Optic Nerve Fibers and Selective Sparing of the Small Fibers.
Invest Ophthalmol Vis Sci. 2024;65:40.
PubMed Abstract available

SKERSWETAT J, Ross NC, Idman-Rait C, Sun K, et al
Visual Performance of People With Albinism Assessed With Generalizable and Adaptive AIM and FInD Methods.
Invest Ophthalmol Vis Sci. 2024;65:34.
PubMed Abstract available

DAI Y, Mao S, Zang X, Ge H, et al
RTP4 Enhances Corneal HSV-1 Infection in Mice With Type 2 Diabetes Mellitus.
Invest Ophthalmol Vis Sci. 2024;65:36.
PubMed Abstract available

August 2024

XU Y, Huang S, Zhou S, Wang X, et al
Iron Chelator Deferiprone Restores Iron Homeostasis and Inhibits Retinal Neovascularization in Experimental Neovascular Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2024;65:5.
PubMed Abstract available

BOSCIA G, Bacherini D, Vujosevic S, Grassi MO, et al
Long-Term Impact of Diabetic Retinopathy on Response to Anti-VEGF Treatment in Neovascular AMD.
Invest Ophthalmol Vis Sci. 2024;65:6.
PubMed Abstract available

ASLAKSEN S, Aukrust I, Molday L, Holtan JP, et al
Functional Characterization of ABCA4 Missense Variants Aids Variant Interpretation and Phenotype Prediction in Patients With ABCA4-Retinal Dystrophies.
Invest Ophthalmol Vis Sci. 2024;65:2.
PubMed Abstract available

SUGALI CK, Rayana NP, Dai J, Harvey DH, et al
GSK3beta Inhibitors Inhibit TGFbeta Signaling in the Human Trabecular Meshwork.
Invest Ophthalmol Vis Sci. 2024;65:3.
PubMed Abstract available

XU M, Chen Q, Luo Y, Chai P, et al
Recurrence in Eyelid Sebaceous Carcinoma: A Multicentric Study of 418 Patients.
Invest Ophthalmol Vis Sci. 2024;65:4.
PubMed Abstract available

CHAN MF
Peer Review in Ophthalmology: A Collaborative Approach to Training the Next Generation of Reviewers.
Invest Ophthalmol Vis Sci. 2024;65:1.
PubMed

WON J, Takahashi H, Ploner SB, Karbole W, et al
Topographic Measurement of the Subretinal Pigment Epithelium Space in Normal Aging and Age-Related Macular Degeneration Using High-Resolution OCT.
Invest Ophthalmol Vis Sci. 2024;65:18.
PubMed Abstract available

HSU CC, Lin FP, Tseng HC, Ho PK, et al
Activation of the ROCK/MYLK Pathway Affects Complex Molecular and Morphological Changes of the Trabecular Meshwork Associated With Ocular Hypertension.
Invest Ophthalmol Vis Sci. 2024;65:17.
PubMed Abstract available

QIN Y, Lei C, Lin T, Han X, et al
Identification of Potential Drug Targets for Myopia Through Mendelian Randomization.
Invest Ophthalmol Vis Sci. 2024;65:13.
PubMed Abstract available

ERDMAN ME, Ch S, Mohiuddin A, Al-Kirwi K, et al
Fabry Disease Rat Model Develops Age- and Sex-Dependent Anterior Segment Ocular Abnormalities.
Invest Ophthalmol Vis Sci. 2024;65:14.
PubMed Abstract available

XUAN M, Wang D, Xiao O, Guo X, et al
Choroidal Vascularity and Axial Length Elongation in Highly Myopic Children: A 2-Year Longitudinal Investigation.
Invest Ophthalmol Vis Sci. 2024;65:7.
PubMed Abstract available

ZHOU H, Liu Y, Zhou T, Yang Z, et al
IL-23 Priming Enhances the Neuroprotective Effects of MSC-Derived Exosomes in Treating Retinal Degeneration.
Invest Ophthalmol Vis Sci. 2024;65:8.
PubMed Abstract available

NUBILE M, Alio Del Barrio JL, Cerino L, Salgari N, et al
Ex Vivo Lenticule Customization for Stromal Lenticule Addition Keratoplasty.
Invest Ophthalmol Vis Sci. 2024;65:9.
PubMed Abstract available

NICOU CM, Passaglia CL
Effect of Ambient Lighting on Intraocular Pressure Rhythms in Rats.
Invest Ophthalmol Vis Sci. 2024;65:16.
PubMed Abstract available

KIM YH, Lee J, Yi SM, Lin MC, et al
Localized Evaporative Cooling Explains Observed Ocular Surface-Temperature Patterns.
Invest Ophthalmol Vis Sci. 2024;65:15.
PubMed Abstract available

FREITAG ST, Lengle MC, Klee S, Heinrich SP, et al
Human Electroretinography Shows Little Polarity Specificity Following Full-Field Ramp Adaptation.
Invest Ophthalmol Vis Sci. 2024;65:11.
PubMed Abstract available

LIU Y, Liu X, Dorizas CA, Hao Z, et al
Macrophages Modulate Optic Nerve Crush Injury Scar Formation and Retinal Ganglion Cell Function.
Invest Ophthalmol Vis Sci. 2024;65:22.
PubMed Abstract available

LIU Y, Li T
Causal Association Between Lipid-Lowering Drugs and Glaucoma: A Drug-Targeted Mendelian Randomization Study.
Invest Ophthalmol Vis Sci. 2024;65:23.
PubMed

ZHUANG X, Li M, Mi L, Zhang X, et al
Molecular Responses of Anti-VEGF Therapy in Neovascular Age-Related Macular Degeneration: Integrative Insights From Multi-Omics and Clinical Imaging.
Invest Ophthalmol Vis Sci. 2024;65:24.
PubMed Abstract available

LEE SS, Lingham G, Clark A, Read SA, et al
Choroidal Changes During and After Discontinuing Long-Term 0.01% Atropine Treatment for Myopia Control.
Invest Ophthalmol Vis Sci. 2024;65:21.
PubMed Abstract available

YANG Y, Han C, Sun Y, Zhao X, et al
Effects of Acute High-Altitude Exposure on Morphology and Function of Retinal Ganglion Cell in Mice.
Invest Ophthalmol Vis Sci. 2024;65:19.
PubMed Abstract available

ABTAHI M, Le D, Ebrahimi B, Dadzie AK, et al
Differential Capillary and Large Vessel Analysis Improves OCTA Classification of Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2024;65:20.
PubMed Abstract available

WAUGH SJ, Fronius M
Landolt C-Tests With "Fixed" Arcmin Separations Detect Amblyopia But Underestimate Crowding in Moderate-to-Severe Amblyopic Children and Adults.
Invest Ophthalmol Vis Sci. 2024;65:33.
PubMed Abstract available

HOGAN K, Cui X, Giangiacomo A, Feola AJ, et al
Postmenopausal Hormone Therapy Was Associated With Later Age of Onset Among Glaucoma Cases.
Invest Ophthalmol Vis Sci. 2024;65:31.
PubMed Abstract available

HOGAN K, Cui X, Giangiacomo A, Feola AJ, et al
Association of Age of Menopause and Glaucoma Diagnosis in Female Veterans.
Invest Ophthalmol Vis Sci. 2024;65:32.
PubMed Abstract available

BORELLA Y, Danielsen N, Markle EM, Snyder VC, et al
Are the Hypo-Reflective Clumps Associated With Age-Related Macular Degeneration in Adaptive Optics Ophthalmoscopy Autofluorescent?
Invest Ophthalmol Vis Sci. 2024;65:28.
PubMed Abstract available

TERAO R, Sohn BS, Yamamoto T, Lee TJ, et al
Cholesterol Accumulation Promotes Photoreceptor Senescence and Retinal Degeneration.
Invest Ophthalmol Vis Sci. 2024;65:29.
PubMed Abstract available

VAN DEN BOSCH QCC, Kilic E, Brosens E
Uveal Melanoma Zebrafish Xenograft Models Illustrate the Mutation Status-Dependent Effect of Compound Synergism or Antagonism.
Invest Ophthalmol Vis Sci. 2024;65:26.
PubMed Abstract available

GOERDT L, Amjad M, Swain TA, McGwin G, et al
Extent and Topography of Subretinal Drusenoid Deposits Associate With Rod-Mediated Vision in Aging and AMD: ALSTAR2 Baseline.
Invest Ophthalmol Vis Sci. 2024;65:25.
PubMed Abstract available

KUMAR B, Mishra M, Cashman S, Kumar-Singh R, et al
Retinal Penetrating Adeno-Associated Virus.
Invest Ophthalmol Vis Sci. 2024;65:30.
PubMed Abstract available

MENG J, Yang XM, Scheer O, Lange J, et al
Pigment Epithelium-Derived Factor Binding to VEGFR-1 (Flt-1) Increases the Survival of Retinal Neurons.
Invest Ophthalmol Vis Sci. 2024;65:27.
PubMed Abstract available

JIANG Y, Yi Z, Zheng Y, Ouyang J, et al
The Systemic Genotype-Phenotype Characterization of PAX6-Related Eye Disease in 164 Chinese Families.
Invest Ophthalmol Vis Sci. 2024;65:46.
PubMed Abstract available

WENDEL BJ, Pandiyan VP, Liu T, Jiang X, et al
Multimodal High-Resolution Imaging in Retinitis Pigmentosa: A Comparison Between Optoretinography, Cone Density, and Visual Sensitivity.
Invest Ophthalmol Vis Sci. 2024;65:45.
PubMed Abstract available

HU Y, Liao L, Morgan IG, Jin L, et al
The Onset and Progression of Myopia Slows in Chinese 15-Year-Old Adolescents Following Vocational Rather Than Academic School Pathways.
Invest Ophthalmol Vis Sci. 2024;65:42.
PubMed Abstract available

LI C, Chen Y, Yang S, Xiong R, et al
Long-Term Prediction and Risk Factors for Incident Visual Field Defect in Nonpathologic High Myopia.
Invest Ophthalmol Vis Sci. 2024;65:43.
PubMed Abstract available

CHOTARD V, Trapani F, Glaziou G, Sermet BS, et al
Altered Functional Responses of the Retina in B6 Albino Tyrc/c Mice.
Invest Ophthalmol Vis Sci. 2024;65:39.
PubMed Abstract available

HEUTINCK PAT, van den Born LI, Vermeer M, Iglesias Gonzales AI, et al
Frequency and Genetic Spectrum of Inherited Retinal Dystrophies in a Large Dutch Pediatric Cohort: The RD5000 Consortium.
Invest Ophthalmol Vis Sci. 2024;65:40.
PubMed Abstract available

YU X, Wei L, Chen Y, Zhang H, et al
Binocular Visual Deficits at Low to High Spatial Frequency in Intermittent Exotropia After Surgery.
Invest Ophthalmol Vis Sci. 2024;65:41.
PubMed Abstract available

MELECCHI A, Canovai A, Amato R, Dal Monte M, et al
Agonism of beta3-Adrenoceptors Inhibits Pathological Retinal Angiogenesis in the Model of Oxygen-Induced Retinopathy.
Invest Ophthalmol Vis Sci. 2024;65:34.
PubMed Abstract available

OLUFSEN ME, Hannibal J, Sorensen NB, Christiansen AT, et al
Wound Healing in a Porcine Model of Retinal Holes.
Invest Ophthalmol Vis Sci. 2024;65:35.
PubMed Abstract available

YIN S, Xu L, Yang K, Fan Q, et al
Gene?Environment Interaction Between CAST Gene and Eye-Rubbing in the Chinese Keratoconus Cohort Study: A Case-Only Study.
Invest Ophthalmol Vis Sci. 2024;65:36.
PubMed Abstract available

HOU C, Wan Q, Xiao L, Xiao Q, et al
Inhibition of Heme Oxygenase 1 Suppresses Growth, Migration, and Invasion, and Regulates Tumor-Infiltrating CD8+ T Cells and in Uveal Melanoma.
Invest Ophthalmol Vis Sci. 2024;65:37.
PubMed Abstract available

ASAI K, Lee HK, Sato S, Shimizu E, et al
The Necroptosis Pathway Is Upregulated in the Cornea in Mice With Ocular Graft-Versus-Host Disease.
Invest Ophthalmol Vis Sci. 2024;65:38.
PubMed Abstract available

July 2024

CHEN X, Huang R, Zhang Z, Song X, et al
BET Bromodomain Inhibition Potentiates Ocular Melanoma Therapy by Inducing Cell Cycle Arrest.
Invest Ophthalmol Vis Sci. 2024;65:11.
PubMed Abstract available

TARALLO V, Magliacane Trotta S, Panico S, D'Orsi L, et al
PlGF and VEGF-A/PlGF Heterodimer are Crucial for Recruitment and Activation of Immune Cells During Choroid Neovascularization.
Invest Ophthalmol Vis Sci. 2024;65:12.
PubMed Abstract available

AGUIRRE B, Lin MC, Araujo E, Lu CH, et al
Epithelial Membrane Protein 2 (EMP2) Blockade Attenuates Pathological Neovascularization in Murine Oxygen-Induced Retinopathy.
Invest Ophthalmol Vis Sci. 2024;65:10.
PubMed Abstract available

GALUH S, Meijer OC, Brinks J, Schlingemann RO, et al
Differential Expression of Sex-Steroid Receptors in the Choroid Aligns With Central Serous Chorioretinopathy Sex Prevalence Across Different Ages.
Invest Ophthalmol Vis Sci. 2024;65:5.
PubMed Abstract available

BARBONI MTS, Szell N, Sohajda Z, Feher T, et al
Pupillary Light Reflex Reveals Melanopsin System Alteration in the Background of Myopia-26, the Female Limited Form of Early-Onset High Myopia.
Invest Ophthalmol Vis Sci. 2024;65:6.
PubMed Abstract available

YING GS, Glynn RJ, Rosner B
Tutorial on Biostatistics: Sample Size and Power Calculation for Ophthalmic Studies With Correlated Binary Eye Outcomes.
Invest Ophthalmol Vis Sci. 2024;65:7.
PubMed Abstract available

ZHENG Y, Tang Y, Yao Y, Ge T, et al
Correlation Analysis of Apparent Diffusion Coefficient Histogram Parameters and Clinicopathologic Features for Prognosis Prediction in Uveal Melanoma.
Invest Ophthalmol Vis Sci. 2024;65:3.
PubMed Abstract available

LUAN J, Zhang Z, Wang Q, Li C, et al
The Role of LC3-Associated Phagocytosis Inhibits the Inflammatory Response in Aspergillus fumigatus Keratitis.
Invest Ophthalmol Vis Sci. 2024;65:4.
PubMed Abstract available

ZHANG N, Zhang P, Deng X, Zhu M, et al
Protective Effect of Nicotinamide Riboside on Glucocorticoid-Induced Glaucoma: Mitigating Mitochondrial Damage and Extracellular Matrix Deposition.
Invest Ophthalmol Vis Sci. 2024;65:1.
PubMed Abstract available

VENKATA SRINIVASAN V, Carter-Dawson L, Patel NB
Retinal Ganglion Cell Content Underlying Standard Automated Perimetry Size I to V Visual Sensitivities in the Non-Human Primate Experimental Glaucoma Model.
Invest Ophthalmol Vis Sci. 2024;65:22.
PubMed Abstract available

YANG H, Cull G, Yang M, Wang L, et al
Differences in Systemic Pulse Waveform Between Individuals With Glaucoma, Glaucoma Suspects, and Healthy Controls.
Invest Ophthalmol Vis Sci. 2024;65:20.
PubMed Abstract available

ROMANO F, Ding X, Yuan M, Vingopoulos F, et al
Progressive Choriocapillaris Changes on Optical Coherence Tomography Angiography Correlate With Stage Progression in AMD.
Invest Ophthalmol Vis Sci. 2024;65:21.
PubMed Abstract available

TANAKA M, Yasuda H, Nakamura S, Shimazawa M, et al
H-151, a Selective STING Inhibitor, Has Potential as a Treatment for Neovascular Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2024;65:16.
PubMed Abstract available

GUYMER RH, Silva R, Ghadessi M, Leal S, et al
ANO2 Genetic Variants and Anti-VEGF Treatment Response in Neovascular AMD: A Pharmacogenetic Substudy of VIEW 1 and VIEW 2.
Invest Ophthalmol Vis Sci. 2024;65:17.
PubMed Abstract available

BOWD C, Belghith A, Rezapour J, Jonas JB, et al
Wide-Field Optical Coherence Tomography Imaging Improves Rate of Change Detection in Progressing Glaucomatous Eyes Compared With Standard-Field Imaging.
Invest Ophthalmol Vis Sci. 2024;65:18.
PubMed Abstract available

MURARI J, Gautier J, Daout J, Krafft L, et al
Foveolar Drusen Decrease Fixation Stability in Pre-Symptomatic AMD.
Invest Ophthalmol Vis Sci. 2024;65:13.
PubMed Abstract available

PANG Y, Bang JW, Kasi A, Li J, et al
Contributions of Brain Microstructures and Metabolism to Visual Field Loss Patterns in Glaucoma Using Archetypal and Information Gain Analyses.
Invest Ophthalmol Vis Sci. 2024;65:15.
PubMed Abstract available

WILKERSON A, Yuksel S, Acharya R, Butovich IA, et al
Physiological Effects of Soat1 Inactivation on Homeostasis of the Mouse Ocular Surface.
Invest Ophthalmol Vis Sci. 2024;65:2.
PubMed Abstract available

ZHU M, Liang J, Wang W, Deng H, et al
Deficits of the "Good" Eye in Amblyopia: Processing Geometric Properties.
Invest Ophthalmol Vis Sci. 2024;65:33.
PubMed Abstract available

NAVNEET S, Ishii M, Rohrer B
Altered Elastin Turnover, Immune Response, and Age-Related Retinal Thinning in a Transgenic Mouse Model With RPE-Specific HTRA1 Overexpression.
Invest Ophthalmol Vis Sci. 2024;65:34.
PubMed Abstract available

RAJASUNDARAM S, Segre AV, Gill D, Woolf B, et al
Independent Effects of Blood Pressure on Intraocular Pressure and Retinal Ganglion Cell Degeneration: A Mendelian Randomization Study.
Invest Ophthalmol Vis Sci. 2024;65:35.
PubMed Abstract available

WU L, Foo LL, Hu Z, Pan W, et al
Bruch's Membrane Opening Changes in Eyes With Myopic Macular Degeneration: AIER-SERI Adult High Myopia Study.
Invest Ophthalmol Vis Sci. 2024;65:36.
PubMed Abstract available

RIEDL S, Schmidt-Erfurth U, Rivail A, Birner K, et al
Sequence of Morphological Changes Preceding Atrophy in Intermediate AMD Using Deep Learning.
Invest Ophthalmol Vis Sci. 2024;65:30.
PubMed Abstract available

HAN Y, Wang X, Xue CC, Jonas JB, et al
Lamina Cribrosa Configurations in Highly Myopic and Non-Highly Myopic Eyes: The Beijing Eye Study.
Invest Ophthalmol Vis Sci. 2024;65:28.
PubMed Abstract available

DING X, Romano F, Garg I, Gan J, et al
Longitudinal Assessment of Intraretinal Microvascular Abnormalities in Diabetic Retinopathy Using Swept-Source Optical Coherence Tomography Angiography.
Invest Ophthalmol Vis Sci. 2024;65:29.
PubMed Abstract available

GE H, Di G, Li B, Han W, et al
Reticulated Retinoic Acid Synthesis is Implicated in the Pathogenesis of Dry Eye in Aqp5 Deficiency Mice.
Invest Ophthalmol Vis Sci. 2024;65:25.
PubMed Abstract available

SCHOLAND KK, Galletti J, Haap W, Santos-Ferreira T, et al
Inhibition of Cathepsin S in Autoimmune CD25KO Mouse Improves Sjogren Disease-Like Lacrimal Gland Pathology.
Invest Ophthalmol Vis Sci. 2024;65:26.
PubMed Abstract available

DE GUIMARAES TAC, Robson AG, de Guimaraes IMC, Laich Y, et al
CDH23-Associated Usher Syndrome: Clinical Features, Retinal Imaging, and Natural History.
Invest Ophthalmol Vis Sci. 2024;65:27.
PubMed Abstract available

COZZI M, Casaluci M, Ruggi G, Airaldi M, et al
In Vivo Correlation Between Macular Pigment Optical Volume and Retinal Layers Thickness.
Invest Ophthalmol Vis Sci. 2024;65:23.
PubMed Abstract available

KUMAR B, Mishra M, Talreja D, Cashman S, et al
Cell-Penetrating Chaperone Nuc1 for Small- and Large-Molecule Delivery Into Retinal Cells and Tissues.
Invest Ophthalmol Vis Sci. 2024;65:31.
PubMed Abstract available

KING-SMITH PE, Begley CG, Braun RJ
High Resolution Images of Human Meibum Spread on Saline.
Invest Ophthalmol Vis Sci. 2024;65:41.
PubMed Abstract available

SAFAI A, Froines C, Slater R, Linderman RE, et al
Quantifying Geographic Atrophy in Age-Related Macular Degeneration: A Comparative Analysis Across 12 Deep Learning Models.
Invest Ophthalmol Vis Sci. 2024;65:42.
PubMed Abstract available

GELMI MC, de Ru AH, van Veelen PA, Tjokrodirijo RTN, et al
Protein and mRNA Expression in Uveal Melanoma Cell Lines Are Related to GNA and BAP1 Mutation Status.
Invest Ophthalmol Vis Sci. 2024;65:37.
PubMed Abstract available

JONAS JB, Bikbov MM, Kazakbaeva GM, Wang YX, et al
Myopic Macular Atrophy in the Two-Continent Population-Based Study.
Invest Ophthalmol Vis Sci. 2024;65:38.
PubMed Abstract available

HE L, Wang W, Ma L, Huang T, et al
Optimization-Based Pairwise Interaction Point Process (O-PIPP): A Precise and Universal Retinal Mosaic Modeling Approach.
Invest Ophthalmol Vis Sci. 2024;65:39.
PubMed Abstract available

KAR D, Amjad M, Corradetti G, Swain TA, et al
Choriocapillaris Impairment, Visual Function, and Distance to Fovea in Aging and Age-Related Macular Degeneration: ALSTAR2 Baseline.
Invest Ophthalmol Vis Sci. 2024;65:40.
PubMed Abstract available

LIU T, Hung PT, Wang X, Girard MJA, et al
Effect of Eye Globe and Optic Nerve Morphologies on Gaze-Induced Optic Nerve Head Deformations.
Invest Ophthalmol Vis Sci. 2024;65:48.
PubMed Abstract available

IQBAL F, Stapleton F, Masoudi S, Papas EB, et al
Meibomian Gland Shortening Is Associated With Altered Meibum Composition.
Invest Ophthalmol Vis Sci. 2024;65:49.
PubMed Abstract available

LI Q, Pu L, Cheng S, Tang S, et al
Pigment Dispersion Contributes to Ocular Immune Privilege in a DBA/2J Mouse Model of Pigmentary Glaucoma.
Invest Ophthalmol Vis Sci. 2024;65:51.
PubMed Abstract available

WU Z, Pfau M, Fleckenstein M, Guymer RH, et al
Microperimetry Characteristics of Regions With a Truly Nonresponding Location: Implications for Atrophic Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2024;65:44.
PubMed Abstract available

PUNDLIK S, Tomasi M, Houston KE, Kumar A, et al
Gaze Scanning on Mid-Block Sidewalks by Pedestrians With Homonymous Hemianopia With or Without Spatial Neglect.
Invest Ophthalmol Vis Sci. 2024;65:46.
PubMed Abstract available

LEE EJ, Han DK, Roh YJ, Kim TW, et al
Underlying Microstructure of the Lamina Cribrosa at the Site of Microvasculature Dropout.
Invest Ophthalmol Vis Sci. 2024;65:47.
PubMed Abstract available

XIONG Z, Kwapong WR, Liu S, Chen T, et al
Association of Retinal Biomarkers With the Subtypes of Ischemic Stroke and an Automated Classification Model.
Invest Ophthalmol Vis Sci. 2024;65:50.
PubMed Abstract available

Erratum in: Multi-Contrast Magnetic Resonance Imaging of Visual White Matter Pathways in Patients With Glaucoma.
Invest Ophthalmol Vis Sci. 2024;65:43.
PubMed

HUANG WC, Ohnsman CM, Atiskova Y, Falabella P, et al
OCT Biomarkers in Ocular CLN2 Disease in Patients Treated With Intraventricular Enzyme Replacement Therapy.
Invest Ophthalmol Vis Sci. 2024;65:45.
PubMed Abstract available

June 2024

LYU S, Zhang T, Peng P, Cao D, et al
Involvement of cGAS/STING Signaling in the Pathogenesis of Candida albicans Keratitis: Insights From Genetic and Pharmacological Approaches.
Invest Ophthalmol Vis Sci. 2024;65:13.
PubMed Abstract available

RAZ D, Ben-Yaakov K, Levi M, Bertolin M, et al
Mitochondria Transplantation Promotes Corneal Epithelial Wound Healing.
Invest Ophthalmol Vis Sci. 2024;65:14.
PubMed Abstract available

KAI C, Oie Y, Nishida N, Doi S, et al
Associations Between Visual Functions and Severity Gradings, Corneal Scatter, or Higher-Order Aberrations in Fuchs Endothelial Corneal Dystrophy.
Invest Ophthalmol Vis Sci. 2024;65:15.
PubMed Abstract available

ENGELMANN J, Moukaddem D, Gago L, Strang N, et al
Applicability of Oculomics for Individual Risk Prediction: Repeatability and Robustness of Retinal Fractal Dimension Using DART and AutoMorph.
Invest Ophthalmol Vis Sci. 2024;65:10.
PubMed Abstract available

STINO H, Huber KL, Kunze L, Steiner I, et al
Intereye Microvascular Differences in Patients With Same-Stage Diabetic Retinopathy Revealed by OCTA.
Invest Ophthalmol Vis Sci. 2024;65:11.
PubMed Abstract available

PARROTT AC, Coburn PS, Miller FC, LaGrow AL, et al
The Role of CCL Chemokines in Experimental Staphylococcus aureus Endophthalmitis.
Invest Ophthalmol Vis Sci. 2024;65:12.
PubMed Abstract available

CHEN Y, Yu J, Ge S, Jia R, et al
An Overview of Optic Pathway Glioma With Neurofibromatosis Type 1: Pathogenesis, Risk Factors, and Therapeutic Strategies.
Invest Ophthalmol Vis Sci. 2024;65:8.
PubMed Abstract available

PAREKH B, Duncan JL, Samarakoon L, Melia M, et al
Self-Reported Functional Vision in USH2A-Associated Retinal Degeneration as Measured by the Michigan Retinal Degeneration Questionnaire.
Invest Ophthalmol Vis Sci. 2024;65:5.
PubMed Abstract available

TURA A, Zhu Y, Vardanyan S, Prasuhn M, et al
Radiation-Induced DNA Damage in Uveal Melanoma Is Influenced by Dose Delivery and Chromosome 3 Status.
Invest Ophthalmol Vis Sci. 2024;65:7.
PubMed Abstract available

CHOI M, Toscano C, Edman MC, de Paiva CS, et al
The Aging Lacrimal Gland of Female C57BL/6J Mice Exhibits Multinucleate Macrophage Infiltration Associated With Lipid Dysregulation.
Invest Ophthalmol Vis Sci. 2024;65:1.
PubMed Abstract available

JIANG K, Zhang F, Chen Y, Li X, et al
Fosfenopril Attenuates Inflammatory Response in Diabetic Dry Eye Models by Inhibiting the TLR4/NF-kappaB/NLRP3 Signaling Pathway.
Invest Ophthalmol Vis Sci. 2024;65:2.
PubMed Abstract available

VALMAGGIA P, Cattin PC, Sandkuhler R, Inglin N, et al
Time-Resolved Dynamic Optical Coherence Tomography for Retinal Blood Flow Analysis.
Invest Ophthalmol Vis Sci. 2024;65:9.
PubMed Abstract available

ENGELMANN J, Burke J, Hamid C, Reid-Schachter M, et al
Choroidalyzer: An Open-Source, End-to-End Pipeline for Choroidal Analysis in Optical Coherence Tomography.
Invest Ophthalmol Vis Sci. 2024;65:6.
PubMed Abstract available

JENDRITZA R, Stingl K, Strasser T, Jung R, et al
Influencing Factors on Pupillary Light Responses as a Biomarker for Local Retinal Function in a Large Normative Cohort.
Invest Ophthalmol Vis Sci. 2024;65:3.
PubMed Abstract available

CONNOLLY E, Knight SP, Duggan E, Scarlett S, et al
Cardiovascular Autonomic Function and Progression of Age-Related Macular Degeneration in The Irish Longitudinal Study of Ageing (TILDA).
Invest Ophthalmol Vis Sci. 2024;65:24.
PubMed Abstract available

AKOTO T, Hadvina R, Jones S, Cai J, et al
Identification of Keratoconus-Related Phenotypes in Three Ppip5k2 Mouse Models.
Invest Ophthalmol Vis Sci. 2024;65:22.
PubMed Abstract available

TSAI HR, Lin YJ, Yeh JI, Lin SM, et al
Use of Sodium-Glucose Co-Transporter 2 Inhibitors in Patients With Type 2 Diabetes and the Incidence of Retinal Vein Occlusion in Taiwan.
Invest Ophthalmol Vis Sci. 2024;65:19.
PubMed Abstract available

DANIELS AB, Sishtla KL, Bogan CM, Pierce JM, et al
Aqueous VEGF-A Levels as a Liquid Biopsy Biomarker of Retinoblastoma Vitreous Seed Response to Therapy.
Invest Ophthalmol Vis Sci. 2024;65:18.
PubMed Abstract available

LIU J, Gao J, Lu P, Wang Y, et al
Mesenchymal Stem Cell-Derived Exosomes as Drug Carriers for Delivering miRNA-29b to Ameliorate Inflammation in Corneal Injury Via Activating Autophagy.
Invest Ophthalmol Vis Sci. 2024;65:16.
PubMed Abstract available

FIESS A, Hartmann A, Mildenberger E, Urschitz MS, et al
Sex-Specific Differences in the Relationship Between Prematurity and Ocular Geometry.
Invest Ophthalmol Vis Sci. 2024;65:23.
PubMed Abstract available

SUN Y, Zhang Y, Shen J, Shi F, et al
A Novel Murine Model for Lupus-Like Ocular Chronic Graft-Versus-Host Disease.
Invest Ophthalmol Vis Sci. 2024;65:20.
PubMed Abstract available

GIM N, Wu Y, Blazes M, Lee CS, et al
A Clinician's Guide to Sharing Data for AI in Ophthalmology.
Invest Ophthalmol Vis Sci. 2024;65:21.
PubMed Abstract available

WU S, Li F, Mo K, Huang H, et al
IGF2BP2 Maintains Retinal Pigment Epithelium Homeostasis by Stabilizing PAX6 and OTX2.
Invest Ophthalmol Vis Sci. 2024;65:17.
PubMed Abstract available

GETZ TE, Chrenek MA, Papania JT, Shelton DA, et al
Conditional Knockouts of Interphotoreceptor Retinoid Binding Protein Suggest Two Independent Mechanisms for Retinal Degeneration and Myopia.
Invest Ophthalmol Vis Sci. 2024;65:32.
PubMed Abstract available

BABCOCK SJ, Curtis AG, Gaston G, Elizondo G, et al
The LCHADD Mouse Model Recapitulates Early-Stage Chorioretinopathy in LCHADD Patients.
Invest Ophthalmol Vis Sci. 2024;65:33.
PubMed Abstract available

ARRIGO A, Aragona E, Del Fabbro S, Balduzzi E, et al
Quantitative Optical Coherence Tomography Detection of New Neovascular Branches and Association With Exudation Recurrence in Neovascular Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2024;65:30.
PubMed Abstract available

DE GUIMARAES TAC, Kalitzeos A, Mahroo OA, van der Spuy J, et al
A Long-Term Retrospective Natural History Study of EFEMP1-Associated Autosomal Dominant Drusen.
Invest Ophthalmol Vis Sci. 2024;65:31.
PubMed Abstract available

SINGH S, Maity M, Shanbhag S, Arunasri K, et al
Lid Margin Microbiome in Stevens-Johnson Syndrome Patients With Lid Margin Keratinization and Severe Dry Eye Disease.
Invest Ophthalmol Vis Sci. 2024;65:28.
PubMed Abstract available

TESTA F, Carreno E, van den Born LI, Melillo P, et al
Multicentric Longitudinal Prospective Study in a European Cohort of MYO7A Patients: Disease Course and Implications for Gene Therapy.
Invest Ophthalmol Vis Sci. 2024;65:25.
PubMed Abstract available

CHENG Y, Hiya F, Li J, Shen M, et al
Calcified Drusen Prevent the Detection of Underlying Choriocapillaris Using Swept-Source Optical Coherence Tomography Angiography.
Invest Ophthalmol Vis Sci. 2024;65:26.
PubMed Abstract available

HONDA T, Nakagawa T, Yuasa T, Tokuda Y, et al
Dysregulation of the TCF4 Isoform in Corneal Endothelial Cells of Patients With Fuchs Endothelial Corneal Dystrophy.
Invest Ophthalmol Vis Sci. 2024;65:27.
PubMed Abstract available

LING X, Xu W, Tang J, Cao Q, et al
The Role of Ubiquitination and the E3 Ligase Nedd4 in Regulating Corneal Epithelial Wound Healing.
Invest Ophthalmol Vis Sci. 2024;65:29.
PubMed Abstract available

GARCIA-PEDRENO C, Tabernero J, Benito A, Artal P, et al
Impact of Peripheral Refractive Errors in Mobility Performance.
Invest Ophthalmol Vis Sci. 2024;65:42.
PubMed Abstract available

LIN N, Chen X, Liu H, Gao N, et al
Ectoine Enhances Mucin Production Via Restoring IL-13/IFN-gamma Balance in a Murine Dry Eye Model.
Invest Ophthalmol Vis Sci. 2024;65:39.
PubMed Abstract available

CHEN Y, Yang S, Liu R, Xiong R, et al
Forecasting Myopic Maculopathy Risk Over a Decade: Development and Validation of an Interpretable Machine Learning Algorithm.
Invest Ophthalmol Vis Sci. 2024;65:40.
PubMed Abstract available

YOSHIOKA H, Ueta M, Fukuoka H, Yokoi N, et al
Alteration of Gene Expression in Pathological Keratinization of the Ocular Surface.
Invest Ophthalmol Vis Sci. 2024;65:37.
PubMed Abstract available

BARRETO P, Farinha C, Coimbra R, Cachulo ML, et al
Unveiling Statins and Genetics in Age-Related Macular Degeneration: The Coimbra Eye Study-Report 9.
Invest Ophthalmol Vis Sci. 2024;65:38.
PubMed Abstract available

YU M, Hao W, Wang M, Ruan Z, et al
Characterizing Retinal Sensitivity and Structure in Congenital Stationary Night Blindness: A Combined Microperimetry and OCT Study.
Invest Ophthalmol Vis Sci. 2024;65:35.
PubMed Abstract available

PATIL CD, Borase H, Gagan S, Sharma P, et al
Rapid NETosis Is an Effector Mechanism to Combat Ocular Herpes Infection.
Invest Ophthalmol Vis Sci. 2024;65:36.
PubMed Abstract available

CUI K, Tang X, Yang B, Fan M, et al
Sema4D Knockout Attenuates Choroidal Neovascularization by Inhibiting M2 Macrophage Polarization Via Regulation of the RhoA/ROCK Pathway.
Invest Ophthalmol Vis Sci. 2024;65:34.
PubMed Abstract available

ZHANG K, Zhang T, He Q, Liang H, et al
Shootin1 Regulates Retinal Ganglion Cell Neurite Development: Insights From an RGC Direct Somatic Cell Reprogramming Model.
Invest Ophthalmol Vis Sci. 2024;65:41.
PubMed Abstract available

May 2024

LI C, Yang Y, Zhu J, Han Y, et al
Visual Tracking in Amblyopia: A Continuous Psychophysical Approach.
Invest Ophthalmol Vis Sci. 2024;65:7.
PubMed Abstract available

MISHRA AV, Vermeirsch S, Lin S, Martin-Gutierrez MP, et al
Sex Distributions in Non-ABCA4 Autosomal Macular Dystrophies.
Invest Ophthalmol Vis Sci. 2024;65:9.
PubMed Abstract available

RAVICHANDRAN S, Snyder PJ, Alber J, Kenny MR, et al
Quantifying Putative Retinal Gliosis in Preclinical Alzheimer's Disease.
Invest Ophthalmol Vis Sci. 2024;65:5.
PubMed Abstract available

ALKHADRAWI AM, Lin LY, Langarica SA, Kim K, et al
Deep-Learning Based Automated Segmentation and Quantitative Volumetric Analysis of Orbital Muscle and Fat for Diagnosis of Thyroid Eye Disease.
Invest Ophthalmol Vis Sci. 2024;65:6.
PubMed Abstract available

LU Y, Hua Y, Wang B, Zhong F, et al
The Robust Lamina Cribrosa Vasculature: Perfusion and Oxygenation Under Elevated Intraocular Pressure.
Invest Ophthalmol Vis Sci. 2024;65:1.
PubMed Abstract available

OMAR WEW, Singh G, McBain AJ, Cruickshank F, et al
Gut Microbiota Profiles in Myopes and Nonmyopes.
Invest Ophthalmol Vis Sci. 2024;65:2.
PubMed Abstract available

HU H, Pang Y, Luo H, Tong B, et al
Noninvasive Light Flicker Stimulation Promotes Optic Nerve Regeneration by Activating Microglia and Enhancing Neural Plasticity in Zebrafish.
Invest Ophthalmol Vis Sci. 2024;65:3.
PubMed Abstract available

CHEN R, Wang Y, Zhang Z, Wang X, et al
The Role of SLIT3-ROBO4 Signaling in Endoplasmic Reticulum Stress-Induced Delayed Corneal Epithelial and Nerve Regeneration.
Invest Ophthalmol Vis Sci. 2024;65:8.
PubMed Abstract available

PANIAGUA-DIAZ AM, Nguyen JH, Artal P, Gui W, et al
Light Scattering by Vitreous of Humans With Vision Degrading Myodesopsia From Floaters.
Invest Ophthalmol Vis Sci. 2024;65:20.
PubMed Abstract available

MAO M, Kuo YM, Yu AK, Labelle-Dumais C, et al
TGFbeta Signaling Dysregulation May Contribute to COL4A1-Related Glaucomatous Optic Nerve Damage.
Invest Ophthalmol Vis Sci. 2024;65:15.
PubMed Abstract available

OWSLEY C, McGwin G Jr, Swain TA, Clark ME, et al
Outer Retinal Thickness Is Associated With Cognitive Function in Normal Aging to Intermediate Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2024;65:16.
PubMed Abstract available

EMAMVERDI M, Vatanatham C, Fasih-Ahmad S, Wang Z, et al
Probing Deposit-Driven Age-Related Macular Degeneration Via Thicknesses of Outer Retinal Bands and Choroid: ALSTAR2 Baseline.
Invest Ophthalmol Vis Sci. 2024;65:17.
PubMed Abstract available

WOSTYN P
Deficient Optic Nerve Sheath Occlusion in NTG Patients: Optic Nerve Damage Due to Translaminar Pressure Imbalance, Glymphatic Failure, or Both?
Invest Ophthalmol Vis Sci. 2024;65:18.
PubMed

KRISTIANSEN M, Holmlund P, Linden C, Eklund A, et al
Author Response: Deficient Optic Nerve Sheath Occlusion in NTG Patients: Optic Nerve Damage Due to Translaminar Pressure Imbalance, Glymphatic Failure, or Both?
Invest Ophthalmol Vis Sci. 2024;65:19.
PubMed

CICINELLI MV, Barlocci E, Giuffre C, Rissotto F, et al
Integrating Machine Learning and Traditional Survival Analysis to Identify Key Predictors of Foveal Involvement in Geographic Atrophy.
Invest Ophthalmol Vis Sci. 2024;65:10.
PubMed Abstract available

DE FRANCESCO T, Mikula E, Lummis W, Sangalang N, et al
Intraocular Pressure While Using Gonioscopy, SLT, and Laser Iridotomy Lenses: An Ex Vivo Study.
Invest Ophthalmol Vis Sci. 2024;65:13.
PubMed Abstract available

HUANG Y, Chen T, Chen X, Wan L, et al
Corneal Stroma Analysis and Related Ocular Manifestations in Recovered COVID-19 Patients.
Invest Ophthalmol Vis Sci. 2024;65:14.
PubMed Abstract available

Erratum in: Transthyretin-Regulated Diabetic Retinopathy Through the VEGFA/PI3K/AKT Pathway.
Invest Ophthalmol Vis Sci. 2024;65:12.
PubMed

COURSON JA, Rumbaut RE, Burns AR
Impact of Obesity and Age on Mouse Corneal Innervation at the Epithelial-Stromal Interface.
Invest Ophthalmol Vis Sci. 2024;65:11.
PubMed Abstract available

YII F, Bernabeu MO, Dhillon B, Strang N, et al
Retinal Changes From Hyperopia to Myopia: Not All Diopters Are Created Equal.
Invest Ophthalmol Vis Sci. 2024;65:25.
PubMed Abstract available

VON SCHULTHESS EL, Maunz A, Chakravarthy U, Holekamp N, et al
Intraretinal Hyper-Reflective Foci Are Almost Universally Present and Co-Localize With Intraretinal Fluid in Diabetic Macular Edema.
Invest Ophthalmol Vis Sci. 2024;65:26.
PubMed Abstract available

HEATH JEFFERY RC, Thompson JA, Lo J, Chelva ES, et al
Retinal Dystrophies Associated With Peripherin-2: Genetic Spectrum and Novel Clinical Observations in 241 Patients.
Invest Ophthalmol Vis Sci. 2024;65:22.
PubMed Abstract available

ABU-ROMMAN A, Scholand KK, Govindarajan G, Yu Z, et al
Age-Related Differences in the Mouse Corneal Epithelial Transcriptome and Their Impact on Corneal Wound Healing.
Invest Ophthalmol Vis Sci. 2024;65:21.
PubMed Abstract available

KUNALA K, Tang JAH, Bowles Johnson KE, Huynh KT, et al
Near Infrared Autofluorescence Lifetime Imaging of Human Retinal Pigment Epithelium Using Adaptive Optics Scanning Light Ophthalmoscopy.
Invest Ophthalmol Vis Sci. 2024;65:27.
PubMed Abstract available

Erratum in: Age-Related Macular Degeneration Choroidal Vascular Distribution Characteristics Based on Indocyanine Green Angiography.
Invest Ophthalmol Vis Sci. 2024;65:23.
PubMed

BROOKS CJ, Chan YM, Fielding J, White OB, et al
Improving Understanding of Visual Snow by Quantifying its Appearance and Effect on Vision.
Invest Ophthalmol Vis Sci. 2024;65:38.
PubMed Abstract available

GUADRON L, Titchener SA, Abbott CJ, Ayton LN, et al
Post-Saccadic Oscillations of the Pupil and Lens Reduce Fixation Stability in Retinitis Pigmentosa and Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2024;65:39.
PubMed Abstract available

CHEN HC, Yang SF, Lee CY, Huang JY, et al
Corneal Endothelial Morphology and Ocular Biometric Indexes in Premature Children With and Without Retinopathy of Prematurity.
Invest Ophthalmol Vis Sci. 2024;65:37.
PubMed Abstract available

PAN M, Kwok S, Pan X, Liu J, et al
Biomechanical Correlations Between the Cornea and the Optic Nerve Head.
Invest Ophthalmol Vis Sci. 2024;65:34.
PubMed Abstract available

FARINHA C, Barreto P, Coimbra R, Machado MB, et al
Age-Related Macular Degeneration and Extramacular Drusen: Genetic Associations in the Coimbra Eye Study.
Invest Ophthalmol Vis Sci. 2024;65:35.
PubMed Abstract available

PANG Y, Hu H, Xu K, Cao T, et al
CD38 Deficiency Protects Mouse Retinal Ganglion Cells Through Activating the NAD+/Sirt1 Pathway in Ischemia-Reperfusion and Optic Nerve Crush Models.
Invest Ophthalmol Vis Sci. 2024;65:36.
PubMed Abstract available

LIU J, Huang C, Cotter SA, Chan LYL, et al
Novel Quantitative Contrast Sensitivity Function Enhances the Prediction of Treatment Outcome and Recurrence in Amblyopia.
Invest Ophthalmol Vis Sci. 2024;65:31.
PubMed Abstract available

WU J, Zhou L, Liu Y, Zhang X, et al
VEGF-C and 5-Fluorouracil Improve Bleb Survival in a Rabbit Glaucoma Surgery Trabeculectomy Model.
Invest Ophthalmol Vis Sci. 2024;65:32.
PubMed Abstract available

KARTHIKEYAN SK, McKendrick AM, Pai VH, Kuzhuppilly NIR, et al
Contrast Discrimination and Global Form Perception in Primary Open-Angle Glaucoma and Primary Angle-Closure Glaucoma.
Invest Ophthalmol Vis Sci. 2024;65:33.
PubMed Abstract available

XU L, Zheng X, Yin S, Yang K, et al
Association of Novel Loci With Keratoconus Susceptibility in a Chinese Genome-Wide Association Study.
Invest Ophthalmol Vis Sci. 2024;65:29.
PubMed Abstract available

LOZANO DC, Yang YF, Cepurna WO, Smoody BF, et al
Profiling IOP-Responsive Genes in the Trabecular Meshwork and Optic Nerve Head in a Rat Model of Controlled Elevation of Intraocular Pressure.
Invest Ophthalmol Vis Sci. 2024;65:41.
PubMed Abstract available

Erratum in: Comparison of Ophthalmic Artery Morphological Characteristics and Retinal Vessel Diameter for Identifying Ocular Ischemic Syndrome.
Invest Ophthalmol Vis Sci. 2024;65:40.
PubMed

April 2024

TU Z, Degg C, Bach M, McLean R, et al
ERG Responses in Albinism, Idiopathic Infantile Nystagmus, and Controls.
Invest Ophthalmol Vis Sci. 2024;65:11.
PubMed Abstract available

VAN POPPELEN NM, Cassoux N, Turunen JA, Naus NC, et al
The Pediatric and Young Adult Choroidal and Ciliary Body Melanoma Genetic Study, A Survey by the European Ophthalmic Oncology Group.
Invest Ophthalmol Vis Sci. 2024;65:12.
PubMed Abstract available

GIASCHI DE, Asare AK, Jost RM, Kelly KR, et al
Motion-Defined Form Perception in Deprivation Amblyopia.
Invest Ophthalmol Vis Sci. 2024;65:13.
PubMed Abstract available

IEZZI R, Scruggs BA, Gandhi J, Zenti FN, et al
Early Choriocapillaris Loss in a Porcine Model of RPE Cell Debridement Precedes Pathology That Simulates Advanced Macular Degeneration.
Invest Ophthalmol Vis Sci. 2024;65:8.
PubMed Abstract available

NORMAN O, Vornanen T, Franssila H, Liinamaa J, et al
Expression of Collagen XIII in Tissues of the Thyroid and Orbit With Relevance to Thyroid-Associated Ophthalmopathy.
Invest Ophthalmol Vis Sci. 2024;65:6.
PubMed Abstract available

HIGGINS BE, Cull G, Gardiner SK
Assessment of Time Lag Between Blood Flow, Retinal Nerve Fiber Layer Thickness and Visual Field Sensitivity Changes in Glaucoma.
Invest Ophthalmol Vis Sci. 2024;65:7.
PubMed Abstract available

DAI E, Liu M, Li S, Zhang X, et al
Identification of Novel FZD4 Mutations in Familial Exudative Vitreoretinopathy and Investigating the Pathogenic Mechanisms of FZD4 Mutations.
Invest Ophthalmol Vis Sci. 2024;65:1.
PubMed Abstract available

XU L, Liu L, Yu B, Yang N, et al
Quantifying the Relationship Between Unilateral Induced Metamorphopsia and Stereopsis Impairment.
Invest Ophthalmol Vis Sci. 2024;65:2.
PubMed Abstract available

FADDA A, Martelli F, Zein WM, Jeffrey B, et al
Statistical Evaluation of ERG Responses: A New Method to Validate Cycle-by-Cycle Recordings in Advanced Retinal Degenerations.
Invest Ophthalmol Vis Sci. 2024;65:3.
PubMed Abstract available

BOATENG AK, Joseph R, Srivastava OP
Dysregulation of Autophagy Occurs During Congenital Cataract Development in betaA3DeltaG91 Mice.
Invest Ophthalmol Vis Sci. 2024;65:4.
PubMed Abstract available

KUNZEL SE, Pompos IM, Flesch LTM, Frentzel DP, et al
Exploring the Impact of Saccharin on Neovascular Age-Related Macular Degeneration: A Comprehensive Study in Patients and Mice.
Invest Ophthalmol Vis Sci. 2024;65:5.
PubMed Abstract available

PUSTI D, Patel NB, Ostrin LA, Nti AN, et al
Peripheral Choroidal Response to Localized Defocus Blur: Influence of Native Peripheral Aberrations.
Invest Ophthalmol Vis Sci. 2024;65:14.
PubMed Abstract available

MARTINEZ-VACAS A, Di Pierdomenico J, Gomez-Ramirez AM, Vidal-Sanz M, et al
Dose-Related Side Effects of Intravitreal Injections of Humanized Anti-Vascular Endothelial Growth Factor in Rats: Glial Cell Reactivity and Retinal Ganglion Cell Loss.
Invest Ophthalmol Vis Sci. 2024;65:10.
PubMed Abstract available

RUFFINI A, Casalucci A, Cara C, Ethier CR, et al
Drug Distribution After Intravitreal Injection: A Mathematical Model.
Invest Ophthalmol Vis Sci. 2024;65:9.
PubMed Abstract available

OSTRIN LA, Sah RP, Queener HM, Patel NB, et al
Short-Term Myopic Defocus and Choroidal Thickness in Children and Adults.
Invest Ophthalmol Vis Sci. 2024;65:22.
PubMed Abstract available

LEONARDI A, Donato A, Rosani U, Di Stefano A, et al
Endoplasmic Reticulum Stress and Unfolded Protein Response in Vernal Keratoconjunctivitis.
Invest Ophthalmol Vis Sci. 2024;65:23.
PubMed Abstract available

CHEN X, Mangalesh S, He J, Winter KP, et al
Early Single-Examination Optical Coherence Tomography Biomarkers for Treatment-Requiring Retinopathy of Prematurity.
Invest Ophthalmol Vis Sci. 2024;65:21.
PubMed Abstract available

ZHOU S, Weng L, Zhou C, Zhou J, et al
Reduced Monocular Luminance Promotes Fusion But Not Mixed Perception in Amblyopia.
Invest Ophthalmol Vis Sci. 2024;65:15.
PubMed Abstract available

GRISSIM G, Walesa A, Follett HM, Higgins BP, et al
Longitudinal Assessment of OCT-Based Measures of Foveal Cone Structure in Achromatopsia.
Invest Ophthalmol Vis Sci. 2024;65:16.
PubMed Abstract available

MURUGAN S, de Campos VS, Ghag SA, Ng M, et al
Characterization of a Novel Mouse Model for Fuchs Endothelial Corneal Dystrophy.
Invest Ophthalmol Vis Sci. 2024;65:18.
PubMed Abstract available

MENG M, Chaqour B, O'Neill N, Dine K, et al
Comparison of Brn3a and RBPMS Labeling to Assess Retinal Ganglion Cell Loss During Aging and in a Model of Optic Neuropathy.
Invest Ophthalmol Vis Sci. 2024;65:19.
PubMed Abstract available

UNTAROIU A, Reis LM, Higgins BP, Walesa A, et al
In Vivo Assessment of Retinal Phenotypes in Axenfeld-Rieger Syndrome.
Invest Ophthalmol Vis Sci. 2024;65:20.
PubMed Abstract available

GLEBER-NETTO FO, Nagarajan P, Sagiv O, Pickering CR, et al
Histologic and Genomic Analysis of Conjunctival SCC in African and American Cohorts Reveal UV Light and HPV Signatures and High Tumor Mutation Burden.
Invest Ophthalmol Vis Sci. 2024;65:24.
PubMed Abstract available

Erratum in: Clinical Significance of Recurrent Disc Hemorrhage and Choroidal Microvasculature Dropout on Optical Coherence Tomography Angiography in Glaucoma.
Invest Ophthalmol Vis Sci. 2024;65:17.
PubMed

LIGHTFOOT JD, Adams EM, Kamath MM, Wells BL, et al
Aspergillus fumigatus Hypoxia Adaptation Is Critical for the Establishment of Fungal Keratitis.
Invest Ophthalmol Vis Sci. 2024;65:31.
PubMed Abstract available

BOWLES JOHNSON KE, Tang JAH, Kunala K, Huynh KT, et al
Fluorescence Lifetime Imaging of Human Retinal Pigment Epithelium in Pentosan Polysulfate Toxicity Using Adaptive Optics Scanning Light Ophthalmoscopy.
Invest Ophthalmol Vis Sci. 2024;65:27.
PubMed Abstract available

CICINELLI MV, Montesano G, Berni A, Scandale P, et al
Photoreceptor Integrity in MEWDS: Longitudinal Structure-Function Correlations.
Invest Ophthalmol Vis Sci. 2024;65:28.
PubMed Abstract available

HAN X, Li H, Zhang D, Li H, et al
Longitudinal Natural History Study of Visual Function in Bietti Crystalline Dystrophy: Implications for Early Intervention.
Invest Ophthalmol Vis Sci. 2024;65:25.
PubMed Abstract available

FAHRENTHOLD BK, Cavanaugh MR, Tamhankar M, Lam BL, et al
Training in Cortically Blinded Fields Appears to Confer Patient-Specific Benefit Against Retinal Thinning.
Invest Ophthalmol Vis Sci. 2024;65:29.
PubMed Abstract available

MA L, Yang L, Wang X, Zhao L, et al
CGRP Released by Corneal Sensory Nerve Maintains Tear Secretion of the Lacrimal Gland.
Invest Ophthalmol Vis Sci. 2024;65:30.
PubMed Abstract available

HICKS RM, Ji X, Zou Y, Sultana S, et al
Differences in Childhood Growth Parameters Between Patients With Somatic and Heritable Retinoblastoma.
Invest Ophthalmol Vis Sci. 2024;65:39.
PubMed Abstract available

TCHATCHOUANG A, Brunette I, Rochette PJ, Proulx S, et al
Expression and Impact of Fibronectin, Tenascin-C, Osteopontin, and Type XIV Collagen in Fuchs Endothelial Corneal Dystrophy.
Invest Ophthalmol Vis Sci. 2024;65:38.
PubMed Abstract available

WIECEK E, Kosovicheva A, Ahmed Z, Nabasaliza A, et al
Peripheral Binocular Imbalance in Anisometropic and Strabismic Amblyopia.
Invest Ophthalmol Vis Sci. 2024;65:36.
PubMed Abstract available

FADAKAR K, Rahmani S, Tedeschi T, Lavine JA, et al
Short Term Effect of Pre-Operative Anti-VEGF on Angiogenic and Fibrotic Profile of Fibrovascular Membranes of Proliferative Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2024;65:37.
PubMed Abstract available

SHAHHOSSEIN-DASTJERDI S, Koina ME, Fatseas G, Arfuso F, et al
Autophagy and Exocytosis of Lipofuscin Into the Basolateral Extracellular Space of Human Retinal Pigment Epithelium From Fetal Development to Adolescence.
Invest Ophthalmol Vis Sci. 2024;65:32.
PubMed Abstract available

WILLIAMS BL, Zouache MA, Seager NA, Pappas CM, et al
Levels of the HtrA1 Protein in Serum and Vitreous Humor Are Independent of Genetic Risk for Age-Related Macular Degeneration at the 10q26 Locus.
Invest Ophthalmol Vis Sci. 2024;65:34.
PubMed Abstract available

KHAPUINAMAI A, Rudraprasad D, Pandey S, Gandhi J, et al
Global Transcriptomic Profiling of Innate and Adaptive Immunity During Aspergillus flavus Endophthalmitis in a Murine Model.
Invest Ophthalmol Vis Sci. 2024;65:44.
PubMed Abstract available

SASSMANNSHAUSEN M, Dongelci S, Vaisband M, von der Emde L, et al
Spatially Resolved Association of Structural Biomarkers on Retinal Function in Non-Exudative Age-Related Macular Degeneration Over 4 Years.
Invest Ophthalmol Vis Sci. 2024;65:45.
PubMed Abstract available

TANG Y, Dou S, Wei C, Sun Z, et al
Single-Nuclei Characterization of Lacrimal Gland in Scopolamine-Induced Dry Eye Disease.
Invest Ophthalmol Vis Sci. 2024;65:46.
PubMed Abstract available

UPRETI A, Hoang TV, Li M, Tangeman JA, et al
miR-26 Deficiency Causes Alterations in Lens Transcriptome and Results in Adult-Onset Cataract.
Invest Ophthalmol Vis Sci. 2024;65:42.
PubMed Abstract available

LIM RR, Shirali S, Rowlan J, Engel AL, et al
CFH Haploinsufficiency and Complement Alterations in Early-Onset Macular Degeneration.
Invest Ophthalmol Vis Sci. 2024;65:43.
PubMed Abstract available

TAN X, Chen Q, Chen Z, Sun Z, et al
Mitochondrial DNA-Activated cGAS-STING Signaling in Environmental Dry Eye.
Invest Ophthalmol Vis Sci. 2024;65:33.
PubMed Abstract available

March 2024

HAO J, Wang M, Liu J, Yusufu M, et al
Alteration of Neurotrophic Factors and Innervation in Extraocular Muscles of Individuals With Concomitant Esotropia.
Invest Ophthalmol Vis Sci. 2024;65:1.
PubMed Abstract available

WOERTZ EN, Ayala GD, Wynne N, Tarima S, et al
Quantitative Foveal Structural Metrics as Predictors of Visual Acuity in Human Albinism.
Invest Ophthalmol Vis Sci. 2024;65:3.
PubMed Abstract available

SACHDEVA MM, Lee Y, Unlu EK, Koseoglu ND, et al
Tandem Mass Tag LC-MS/MS of Aqueous Humor From Individuals With Type 2 Diabetes Without Retinopathy Reveals Early Dysregulation of Synaptic Proteins.
Invest Ophthalmol Vis Sci. 2024;65:16.
PubMed Abstract available

SHEN M, Han X, Yang Y, Huang H, et al
Longitudinal Changes in Choroidal Thickness Varied With Refractive Progression in Myopic and Non-Myopic Children: A Two-Year Cohort Study.
Invest Ophthalmol Vis Sci. 2024;65:17.
PubMed Abstract available

BORRELLI E, Barresi C, Ricardi F, Berni A, et al
Distinct Pathways of Macular Atrophy in Type 3 Macular Neovascularization Associated With AMD.
Invest Ophthalmol Vis Sci. 2024;65:18.
PubMed Abstract available

CAKIR GB, Murray J, Dulaney C, Ghasia F, et al
Multifaceted Interactions of Stereoacuity, Inter-Ocular Suppression, and Fixation Eye Movement Abnormalities in Amblyopia and Strabismus.
Invest Ophthalmol Vis Sci. 2024;65:19.
PubMed Abstract available

SANG T, Wang Y, Wang Z, Sun D, et al
NEAT1 Deficiency Promotes Corneal Epithelial Wound Healing by Activating cAMP Signaling Pathway.
Invest Ophthalmol Vis Sci. 2024;65:10.
PubMed Abstract available

JIN Y, Li S, Jiang Z, Sun L, et al
Genotype-Phenotype of CRB1-Associated Early-Onset Retinal Dystrophy: Novel Insights on Retinal Architecture and Therapeutic Window for Clinical Trials.
Invest Ophthalmol Vis Sci. 2024;65:11.
PubMed Abstract available

ZHANG X, Liang Y, Huang Y, Liu S, et al
Evaluation of the Observational Associations and Shared Genetics Between Glaucoma With Depression and Anxiety.
Invest Ophthalmol Vis Sci. 2024;65:12.
PubMed Abstract available

VON DER EMDE L, Rennen GC, Vaisband M, Hasenauer J, et al
Personalized Lens Correction Improves Quantitative Fundus Autofluorescence Analysis.
Invest Ophthalmol Vis Sci. 2024;65:13.
PubMed Abstract available

LIU F, Ye Y, Yang W, Wang J, et al
Quantitative Evaluation of the Topographical Maps of Three-Dimensional Choroidal Vascularity Index in Children With Different Degrees of Myopia.
Invest Ophthalmol Vis Sci. 2024;65:14.
PubMed Abstract available

GAGAN S, Khapuinamai A, Kapoor D, Sharma P, et al
Exploring Heparanase Levels in Tears: Insights From Herpes Simplex Virus-1 Keratitis Patients and Animal Studies.
Invest Ophthalmol Vis Sci. 2024;65:7.
PubMed Abstract available

DAICH VARELA M, Dixit M, Kalitzeos A, Michaelides M, et al
Adaptive Optics Retinal Imaging in RDH12-Associated Early Onset Severe Retinal Dystrophy.
Invest Ophthalmol Vis Sci. 2024;65:9.
PubMed Abstract available

CURCIO CA, Kar D, Owsley C, Sloan KR, et al
Age-Related Macular Degeneration, a Mathematically Tractable Disease.
Invest Ophthalmol Vis Sci. 2024;65:4.
PubMed Abstract available

OH SE, Shin HJ, Park CK, Park HL, et al
Clinical Significance of Recurrent Disc Hemorrhage and Choroidal Microvasculature Dropout on Optical Coherence Tomography Angiography in Glaucoma.
Invest Ophthalmol Vis Sci. 2024;65:5.
PubMed Abstract available

BIKBOV MM, Gilmanshin TR, Kazakbaeva GM, Panda-Jonas S, et al
Prevalence of Myopic Maculopathy Among the Very Old: The Ural Very Old Study.
Invest Ophthalmol Vis Sci. 2024;65:29.
PubMed Abstract available

QIN S, Ma L, Ferreira F, Brown C, et al
Diabetic Ocular Surface Has Defects in Oxygen Uptake Revealed by Optic Fiber Microsensor.
Invest Ophthalmol Vis Sci. 2024;65:27.
PubMed Abstract available

CHEN DF, Wang C, Si Y, Lu X, et al
Natural History and Risk Factors for Glaucoma Progression in Chinese Patients With Normal-Tension Glaucoma.
Invest Ophthalmol Vis Sci. 2024;65:28.
PubMed Abstract available

KUNISETTY B, Martin-Giacalone BA, Zhao X, Luna PN, et al
High Clinical Exome Sequencing Diagnostic Rates and Novel Phenotypic Expansions for Nonisolated Microphthalmia, Anophthalmia, and Coloboma.
Invest Ophthalmol Vis Sci. 2024;65:25.
PubMed Abstract available

GUO X, Zhang Z, Chen Q, Wang L, et al
Whole Genome Sequencing Highlights the Pathogenic Profile in Nocardia Keratitis.
Invest Ophthalmol Vis Sci. 2024;65:26.
PubMed Abstract available

BROWN SF, Nguyen H, Mzyk P, De Ieso ML, et al
ANGPTL7 and Its Role in IOP and Glaucoma.
Invest Ophthalmol Vis Sci. 2024;65:22.
PubMed Abstract available

MOIR J, Hyman MJ, Gonnah R, Flores A, et al
The Association Between Metformin Use and New-Onset ICD Coding of Geographic Atrophy.
Invest Ophthalmol Vis Sci. 2024;65:23.
PubMed Abstract available

SEO S, Sonn SK, Kweon HY, Jin J, et al
Primary Cilium in Neural Crest Cells Crucial for Anterior Segment Development and Corneal Avascularity.
Invest Ophthalmol Vis Sci. 2024;65:30.
PubMed Abstract available

NIU J, Zhu W, Jin X, Teng X, et al
Novel Splicing Variants in the ARR3 Gene Cause the Female-Limited Early-Onset High Myopia.
Invest Ophthalmol Vis Sci. 2024;65:32.
PubMed Abstract available

ZHENG F, Su J, Wang J, Zhan Q, et al
Expression of ATP-Binding Cassette Transporter A1 (ABCA1) in Eyelid Tissues and Meibomian Gland Epithelial Cells.
Invest Ophthalmol Vis Sci. 2024;65:24.
PubMed Abstract available

MESSNER A, Aranha Dos Santos V, Puchner S, Stegmann H, et al
The Impact of Photopigment Bleaching on the Human Rod Photoreceptor Subretinal Space Measured Via Optical Coherence Tomography.
Invest Ophthalmol Vis Sci. 2024;65:20.
PubMed Abstract available

LIU S, Chen H, Xie H, Liu X, et al
Substrate Stiffness Modulates Stemness and Differentiation of Rabbit Corneal Endothelium Through the Paxillin-YAP Pathway.
Invest Ophthalmol Vis Sci. 2024;65:15.
PubMed Abstract available

LEUNG J, Pollalis D, Nair GKG, Bailey JK, et al
Isolation and Characterization of Extracellular Vesicles Through Orthogonal Approaches for the Development of Intraocular EV Therapy.
Invest Ophthalmol Vis Sci. 2024;65:6.
PubMed Abstract available

DATTA A, Lee JH, Truong T, Flandrin O, et al
Persistence of Contact Lens-Induced Corneal Parainflammation Following Lens Removal.
Invest Ophthalmol Vis Sci. 2024;65:8.
PubMed Abstract available

GAO N, Yu FS
Lack of Elevated Expression of TGFbeta3 Contributes to the Delay of Epithelial Wound Healing in Diabetic Corneas.
Invest Ophthalmol Vis Sci. 2024;65:35.
PubMed Abstract available

LU Y, Zou L, Wang W, Chen R, et al
Effects of Monocular Flicker on Binocular Imbalance in Amblyopic and Nonamblyopic Adults.
Invest Ophthalmol Vis Sci. 2024;65:33.
PubMed Abstract available

LIU M, Dai E, Yang M, Li S, et al
Investigating the Impact of Dimer Interface Mutations on Norrin's Secretion and Norrin/beta-Catenin Pathway Activation.
Invest Ophthalmol Vis Sci. 2024;65:31.
PubMed Abstract available

GONG C, Yang M, Long H, Liu X, et al
IL-6-Derived Autocrine Lactate Promotes Immune Escape of Uveal Melanoma.
Invest Ophthalmol Vis Sci. 2024;65:37.
PubMed Abstract available

ZHANG W, Huang H, Liu X, Zhang L, et al
scRNA-Seq: First Atlas and Cellular Landscape of Lacrimal Sac: Implications in Primary Acquired Nasolacrimal Duct Obstruction Pathogenesis.
Invest Ophthalmol Vis Sci. 2024;65:38.
PubMed Abstract available

FIESS A, Volmering C, Gissler S, Mildenberger E, et al
Macular Curvature in Adults Born Preterm With and Without ROP: Results from the Gutenberg Prematurity Eye Study.
Invest Ophthalmol Vis Sci. 2024;65:39.
PubMed Abstract available

February 2024

SAINT-AMOUR D, Lefebvre L, Bertrand Pilon C, Hess RF, et al
Flash Suppression Reveals an Additional Nonvisual Extrastriate Contribution for Amblyopic Suppression.
Invest Ophthalmol Vis Sci. 2024;65:41.
PubMed Abstract available

NAVNEET S, Wilson K, Rohrer B
Muller Glial Cells in the Macula: Their Activation and Cell-Cell Interactions in Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci. 2024;65:42.
PubMed Abstract available

DAICH VARELA M, Schiff E, Malka S, Wright G, et al
PHYH c.678+5G>T Leads to In-Frame Exon Skipping and Is Associated With Attenuated Refsum Disease.
Invest Ophthalmol Vis Sci. 2024;65:38.
PubMed Abstract available

BERYOZKIN A, Sher I, Ehrenberg M, Zur D, et al
Best Disease: Global Mutations Review, Genotype-Phenotype Correlation, and Prevalence Analysis in the Israeli Population.
Invest Ophthalmol Vis Sci. 2024;65:39.
PubMed Abstract available

CHAUDHARY P, Lockwood H, Stowell C, Bushong E, et al
Retrolaminar Demyelination of Structurally Intact Axons in Nonhuman Primate Experimental Glaucoma.
Invest Ophthalmol Vis Sci. 2024;65:36.
PubMed Abstract available

Erratum in: Familial Whole Exome Sequencing Study of 30 Families With Early-Onset High Myopia.
Invest Ophthalmol Vis Sci. 2024;65:40.
PubMed

ZHANG J, Sabarinathan R, Bubel T, Jia W, et al
Spectral Dependence of Light Exposure on Retinal Pigment Epithelium Disruption in Living Primate Retina.
Invest Ophthalmol Vis Sci. 2024;65:43.
PubMed Abstract available

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